Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.027 | 0.027 |
Schistosoma mansoni | hypothetical protein | 0.0089 | 0.0455 | 0.0455 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.02 | 0.1392 | 0.4803 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0378 | 0.2897 | 1 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0069 | 0.0284 | 0.0981 |
Onchocerca volvulus | 0.0178 | 0.1211 | 0.3689 | |
Onchocerca volvulus | 0.0069 | 0.0284 | 0.0221 | |
Schistosoma mansoni | notch | 0.0089 | 0.0455 | 0.0455 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0178 | 0.1211 | 0.1211 |
Brugia malayi | Trypsin family protein | 0.0069 | 0.0284 | 0.0981 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.027 | 0.0931 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0378 | 0.2897 | 0.2897 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0378 | 0.2897 | 0.2897 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0062 | 0.0225 | 0.0778 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0089 | 0.0455 | 0.1571 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | EGF-like domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Brugia malayi | EGF-like domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | nuclear hormone receptor | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | ecdysone receptor | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0378 | 0.2897 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.0339 | 0.0339 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0097 | 0.0334 |
Onchocerca volvulus | Slit protein homolog | 0.0089 | 0.0455 | 0.086 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0378 | 0.2897 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0378 | 0.2897 | 1 |
Leishmania major | cathepsin L-like protease | 0.0125 | 0.0757 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0378 | 0.2897 | 1 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0089 | 0.0455 | 0.086 |
Echinococcus multilocularis | neural cadherin | 0.0089 | 0.0455 | 0.1571 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0125 | 0.0757 | 1 |
Schistosoma mansoni | cell polarity protein | 0.0089 | 0.0455 | 0.0455 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0358 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0378 | 0.2897 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.2897 | 1 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0062 | 0.0225 | 0.0778 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0378 | 0.2897 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0089 | 0.0455 | 0.1571 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0378 | 0.2897 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0358 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0284 | 0.0284 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.027 | 0.0931 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0077 | 0.0358 | 0.3982 |
Loa Loa (eye worm) | trypsin family protein | 0.0069 | 0.0284 | 0.0981 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0378 | 0.2897 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Brugia malayi | hypothetical protein | 0.02 | 0.1392 | 0.4803 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | ecdysteroid receptor | 0.0378 | 0.2897 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0178 | 0.1211 | 0.3689 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0178 | 0.1211 | 0.418 |
Schistosoma mansoni | hypothetical protein | 0.0089 | 0.0455 | 0.0455 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0051 | 0.0133 | 0.0606 |
Echinococcus multilocularis | protein jagged 1 | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0178 | 0.1211 | 0.1211 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0284 | 0.0981 |
Brugia malayi | Fibulin-1 precursor | 0.0062 | 0.0225 | 0.0778 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.0133 | 0.046 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0284 | 0.0981 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0069 | 0.0284 | 0.0981 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0125 | 0.0757 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0106 | 0.0598 | 0.8342 |
Echinococcus granulosus | FTZ F1 alpha | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0062 | 0.0225 | 0.0778 |
Echinococcus granulosus | Mastin | 0.0069 | 0.0284 | 0.0981 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0378 | 0.2897 | 0.2897 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0069 | 0.0284 | 0.0981 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Schistosoma mansoni | nuclear hormone receptor | 0.0178 | 0.1211 | 0.1211 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0097 | 0.0334 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0378 | 0.2897 | 0.2897 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0089 | 0.0455 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1392 | 0.4803 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0378 | 0.2897 | 1 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0062 | 0.0225 | 0.0225 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0062 | 0.0225 | 0.0778 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0069 | 0.0284 | 0.0981 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Toxoplasma gondii | PAN domain-containing protein | 0.0337 | 0.2552 | 1 |
Schistosoma mansoni | septate junction protein | 0.0089 | 0.0455 | 0.0455 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0062 | 0.0225 | 0.0523 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.2897 | 1 |
Echinococcus granulosus | laminin | 0.0062 | 0.0225 | 0.0778 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0378 | 0.2897 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0094 | 0.0502 | 0.1734 |
Brugia malayi | nuclear receptor NHR-67 | 0.0178 | 0.1211 | 0.418 |
Echinococcus multilocularis | protein jagged 1 | 0.0089 | 0.0455 | 0.1571 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Echinococcus granulosus | enteropeptidase | 0.0069 | 0.0284 | 0.0981 |
Echinococcus granulosus | protein jagged 2 | 0.0089 | 0.0455 | 0.1571 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0125 | 0.0757 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0069 | 0.0284 | 0.0284 |
Onchocerca volvulus | 0.0089 | 0.0455 | 0.086 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0378 | 0.2897 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0123 | 0.0423 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0358 | 0.5 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0358 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0378 | 0.2897 | 0.2897 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0378 | 0.2897 | 1 |
Onchocerca volvulus | 0.0069 | 0.0284 | 0.0221 | |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0378 | 0.2897 | 0.2897 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.2897 | 1 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0077 | 0.0358 | 0.1064 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0378 | 0.2897 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0378 | 0.2897 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | notch | 0.0089 | 0.0455 | 0.0455 |
Loa Loa (eye worm) | notch protein | 0.0089 | 0.0455 | 0.1571 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0097 | 0.0334 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0178 | 0.1211 | 0.418 |
Onchocerca volvulus | 0.037 | 0.2834 | 0.9766 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0378 | 0.2897 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Echinococcus multilocularis | laminin | 0.0062 | 0.0225 | 0.0778 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0062 | 0.0225 | 0.0778 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0178 | 0.1211 | 0.418 |
Giardia lamblia | High cysteine protein | 0.0089 | 0.0455 | 0.5 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0089 | 0.0455 | 0.1571 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0069 | 0.0284 | 0.0981 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0098 | 0.0531 | 0.1832 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0358 | 1 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | Trypsin family protein | 0.0069 | 0.0284 | 0.0981 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1392 | 0.4803 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.2897 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0125 | 0.0757 | 1 |
Leishmania major | cathepsin L-like protease | 0.0125 | 0.0757 | 1 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0069 | 0.0284 | 0.0981 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.02 | 0.1392 | 0.4803 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0225 | 0.0778 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Schistosoma mansoni | hypothetical protein | 0.0089 | 0.0455 | 0.0455 |
Brugia malayi | nuclear receptor RXR | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0284 | 0.0981 |
Onchocerca volvulus | 0.0089 | 0.0455 | 0.086 | |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Schistosoma mansoni | nuclear receptor | 0.0178 | 0.1211 | 0.1211 |
Onchocerca volvulus | 0.0089 | 0.0455 | 0.086 | |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0178 | 0.1211 | 0.418 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0051 | 0.0133 | 0.0606 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0378 | 0.2897 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0114 | 0.0666 | 0.8618 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0178 | 0.1211 | 0.418 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0358 | 1 |
Toxoplasma gondii | PAN domain-containing protein | 0.0337 | 0.2552 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.037 | 0.2834 | 0.2834 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | nuclear receptor NHR-88 | 0.0178 | 0.1211 | 0.418 |
Echinococcus multilocularis | notch | 0.0089 | 0.0455 | 0.1571 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0378 | 0.2897 | 1 |
Echinococcus multilocularis | protein jagged 2 | 0.0089 | 0.0455 | 0.1571 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0069 | 0.0284 | 0.0981 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0378 | 0.2897 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0094 | 0.0502 | 0.1734 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0284 | 0.0284 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | Trypsin family protein | 0.037 | 0.2834 | 0.9784 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0378 | 0.2897 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Leishmania major | cathepsin L-like protease | 0.0125 | 0.0757 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0378 | 0.2897 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Echinococcus granulosus | neural cadherin | 0.0089 | 0.0455 | 0.1571 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1392 | 0.4803 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0069 | 0.0284 | 0.0981 |
Onchocerca volvulus | 0.0378 | 0.2897 | 1 | |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0358 | 1 |
Brugia malayi | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0178 | 0.1211 | 0.418 |
Schistosoma mansoni | hypothetical protein | 0.0089 | 0.0455 | 0.0455 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0378 | 0.2897 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.02 | 0.1392 | 0.4803 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.02 | 0.1392 | 0.1392 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0069 | 0.0284 | 0.0981 |
Onchocerca volvulus | 0.0302 | 0.2256 | 0.76 | |
Echinococcus granulosus | delta-like protein 1 | 0.0089 | 0.0455 | 0.1571 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0069 | 0.0284 | 0.0981 |
Schistosoma mansoni | thyroid hormone receptor | 0.0378 | 0.2897 | 0.2897 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | notch | 0.0089 | 0.0455 | 0.0455 |
Mycobacterium tuberculosis | Probable reductase | 0.0106 | 0.0598 | 0.8342 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0378 | 0.2897 | 1 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0062 | 0.0225 | 0.0523 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0117 | 0.0698 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0117 | 0.0698 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0378 | 0.2897 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0178 | 0.1211 | 0.3689 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.02 | 0.1392 | 0.4803 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0106 | 0.0598 | 0.8342 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0077 | 0.0358 | 0.1236 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0106 | 0.0598 | 0.8342 |
Brugia malayi | jmjC domain containing protein | 0.0094 | 0.0502 | 0.1734 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0378 | 0.2897 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0106 | 0.0598 | 0.8342 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0106 | 0.0598 | 0.8236 |
Brugia malayi | steroid hormone receptor | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0531 | 0.1832 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0097 | 0.0334 |
Brugia malayi | Delta serrate ligand family protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | Trypsin family protein | 0.0069 | 0.0284 | 0.0981 |
Onchocerca volvulus | Putative cubilin | 0.0089 | 0.0455 | 0.086 |
Brugia malayi | EGF-like domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0077 | 0.0358 | 1 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0062 | 0.0225 | 0.0778 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.2897 | 1 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0044 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.2834 | 0.9784 |
Brugia malayi | tailless protein | 0.0178 | 0.1211 | 0.418 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0117 | 0.0698 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0358 | 0.1236 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0089 | 0.0455 | 0.1458 |
Echinococcus granulosus | protein jagged 2 | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0089 | 0.0455 | 0.0455 |
Onchocerca volvulus | 0.0089 | 0.0455 | 0.086 | |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0077 | 0.0358 | 0.0358 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0378 | 0.2897 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0178 | 0.1211 | 0.1211 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0378 | 0.2897 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0378 | 0.2897 | 1 |
Echinococcus multilocularis | enteropeptidase | 0.0069 | 0.0284 | 0.0981 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0089 | 0.0455 | 0.0455 |
Schistosoma mansoni | notch | 0.0089 | 0.0455 | 0.0455 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0378 | 0.2897 | 1 |
Echinococcus multilocularis | slit 2 protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | hypothetical protein | 0.0089 | 0.0455 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Schistosoma mansoni | egf-like domain protein | 0.0062 | 0.0225 | 0.0225 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0178 | 0.1211 | 0.418 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0077 | 0.0358 | 0.1064 |
Schistosoma mansoni | slit | 0.0089 | 0.0455 | 0.0455 |
Onchocerca volvulus | 0.0069 | 0.0284 | 0.0221 | |
Loa Loa (eye worm) | DR-78 | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0098 | 0.0531 | 0.1832 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0178 | 0.1211 | 0.418 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0077 | 0.0358 | 0.1236 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.2897 | 1 |
Brugia malayi | conserved hypotetical protein | 0.0178 | 0.1211 | 0.418 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Echinococcus granulosus | notch | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0378 | 0.2897 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0378 | 0.2897 | 1 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0097 | 0.0334 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0378 | 0.2897 | 0.2897 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1392 | 0.4803 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0089 | 0.0455 | 0.1571 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0378 | 0.2897 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0098 | 0.0532 | 0.6591 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0178 | 0.1211 | 0.418 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0178 | 0.1211 | 0.418 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0225 | 0.0778 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0225 | 0.0778 |
Schistosoma mansoni | notch | 0.0089 | 0.0455 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0284 | 0.0981 |
Brugia malayi | EGF-like domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | zinc finger protein | 0.0178 | 0.1211 | 0.1211 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0378 | 0.2897 | 1 |
Echinococcus multilocularis | fibropellin Ia | 0.0089 | 0.0455 | 0.1571 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0378 | 0.2897 | 1 |
Onchocerca volvulus | 0.0089 | 0.0455 | 0.086 | |
Echinococcus granulosus | Tolloid protein 1 | 0.0062 | 0.0225 | 0.0778 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0378 | 0.2897 | 0.2897 |
Echinococcus granulosus | slit 2 protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0098 | 0.0531 | 0.1832 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.037 | 0.2834 | 0.2834 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0378 | 0.2897 | 0.2897 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0044 | 0.0152 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1392 | 0.4803 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0284 | 0.0981 |
Schistosoma mansoni | hypothetical protein | 0.0089 | 0.0455 | 0.0455 |
Loa Loa (eye worm) | Notch2 | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | thyroid hormone receptor | 0.0378 | 0.2897 | 0.2897 |
Brugia malayi | Muscle positioning protein 4 | 0.0089 | 0.0455 | 0.1571 |
Onchocerca volvulus | 0.0069 | 0.0284 | 0.0221 | |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0208 | 0.0717 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.02 | 0.1392 | 0.4803 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | EGF-like domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0225 | 0.0778 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0378 | 0.2897 | 0.2897 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0378 | 0.2897 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.02 | 0.1392 | 0.1392 |
Brugia malayi | notch-like transmembrane receptor | 0.0089 | 0.0455 | 0.1571 |
Echinococcus granulosus | protein jagged 1 | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | nuclear hormone receptor | 0.0378 | 0.2897 | 0.2897 |
Brugia malayi | hypothetical protein | 0.0069 | 0.0284 | 0.0981 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0225 | 0.0778 |
Echinococcus multilocularis | Mastin | 0.0069 | 0.0284 | 0.0981 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0378 | 0.2897 | 1 |
Onchocerca volvulus | 0.0069 | 0.0284 | 0.0221 | |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.2897 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0117 | 0.0698 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Echinococcus granulosus | fibropellin Ia | 0.0089 | 0.0455 | 0.1571 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0097 | 0.0334 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0089 | 0.0455 | 0.1571 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.0133 | 0.046 |
Onchocerca volvulus | 0.0178 | 0.1211 | 0.3689 | |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.2834 | 0.9784 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0106 | 0.0598 | 0.8342 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | hypothetical protein | 0.0089 | 0.0455 | 0.0455 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0125 | 0.0757 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0069 | 0.0284 | 0.0284 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0178 | 0.1211 | 0.418 |
Brugia malayi | nuclear receptor RXR | 0.02 | 0.1392 | 0.4803 |
Brugia malayi | hypothetical protein | 0.02 | 0.1392 | 0.4803 |
Brugia malayi | Probable ClpP-like protease | 0.0077 | 0.0358 | 0.1236 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0378 | 0.2897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0455 | 0.1571 |
Schistosoma mansoni | nuclear hormone receptor | 0.0178 | 0.1211 | 0.1211 |
Schistosoma mansoni | notch | 0.0089 | 0.0455 | 0.0455 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0378 | 0.2897 | 1 |
Echinococcus multilocularis | fibrillin 1 | 0.0062 | 0.0225 | 0.0778 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.798 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.745 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.666 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.609 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.497 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.421 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.394 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.334 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.315 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.296 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.006 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.