Detailed information for compound 1663006

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 4509.37 | Formula: C204H404N6O98
  • H donors: 4 H acceptors: 4 LogP: -12.71 Rotable bonds: 296
    Rule of 5 violations (Lipinski): 2
  • SMILES: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCCNc1nc(C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)c(nc1C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)NCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
  • InChi: 1S/C204H404N6O98/c1-213-15-19-221-31-35-229-47-51-237-63-67-245-79-83-253-95-99-261-111-115-269-127-131-277-143-147-285-159-163-293-175-179-301-191-195-305-187-183-297-171-167-289-155-151-281-139-135-273-123-119-265-107-103-257-91-87-249-75-71-241-59-55-233-43-39-225-27-23-217-11-5-7-205-201-199(203(211)207-9-13-219-25-29-227-41-45-235-57-61-243-73-77-251-89-93-259-105-109-267-121-125-275-137-141-283-153-157-291-169-173-299-185-189-307-197-193-303-181-177-295-165-161-287-149-145-279-133-129-271-117-113-263-101-97-255-85-81-247-69-65-239-53-49-231-37-33-223-21-17-215-3)210-202(206-8-6-12-218-24-28-226-40-44-234-56-60-242-72-76-250-88-92-258-104-108-266-120-124-274-136-140-282-152-156-290-168-172-298-184-188-306-196-192-302-180-176-294-164-160-286-148-144-278-132-128-270-116-112-262-100-96-254-84-80-246-68-64-238-52-48-230-36-32-222-20-16-214-2)200(209-201)204(212)208-10-14-220-26-30-228-42-46-236-58-62-244-74-78-252-90-94-260-106-110-268-122-126-276-138-142-284-154-158-292-170-174-300-186-190-308-198-194-304-182-178-296-166-162-288-150-146-280-134-130-272-118-114-264-102-98-256-86-82-248-70-66-240-54-50-232-38-34-224-22-18-216-4/h5-198H2,1-4H3,(H,205,209)(H,206,210)(H,207,211)(H,208,212)
  • InChiKey: KSYWWHHISYSCSK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0066 0.0307 0.0307
Schistosoma mansoni hypothetical protein 0.0079 0.0388 0.0388
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0079 0.0388 0.0388
Echinococcus granulosus somatostatin receptor 0.0079 0.0388 0.0388
Schistosoma mansoni nAChR subunit 0.0066 0.0307 0.0307
Brugia malayi sulfakinin receptor protein 0.0079 0.0388 0.043
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0066 0.0307 0.0738
Trypanosoma cruzi cardiolipin synthetase, putative 0.0245 0.1408 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0079 0.0388 0.043
Echinococcus granulosus sorting nexin 0.003 0.0091 0.0091
Brugia malayi hypothetical protein 0.0079 0.0388 0.043
Loa Loa (eye worm) hypothetical protein 0.003 0.0091 0.0219
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0694 0.4164 0.4612
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.003 0.009 0.01
Loa Loa (eye worm) PX domain-containing protein 0.003 0.0091 0.0219
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Brugia malayi beta-lactamase 0.0036 0.0123 0.0136
Schistosoma mansoni neurotransmitter gated ion channel 0.003 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0036 0.0123 0.0295
Schistosoma mansoni neuropeptide receptor 0.0079 0.0388 0.0388
Onchocerca volvulus 0.0079 0.0388 0.2628
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0066 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0066 0.0307 0.0738
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Entamoeba histolytica phospholipase D, putative 0.0702 0.4215 1
Brugia malayi Variant SH3 domain containing protein 0.003 0.0091 0.0101
Onchocerca volvulus 0.0036 0.0123 0.0289
Echinococcus granulosus nAChR subunit 0.0066 0.0307 0.0307
Echinococcus granulosus neuropeptides capa receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Brugia malayi PX domain containing protein 0.003 0.0091 0.0101
Echinococcus multilocularis sorting nexin 2 0.003 0.0091 0.0091
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.02 0.02
Schistosoma mansoni biogenic amine receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0634 0.1522
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Loa Loa (eye worm) G-protein coupled receptor 0.0079 0.0388 0.0931
Schistosoma mansoni biogenic amine receptor 0.0079 0.0388 0.0388
Echinococcus granulosus neuropeptides capa receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.003 0.009 0.0217
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0123 0.5
Onchocerca volvulus 0.0079 0.0388 0.2628
Schistosoma mansoni sorting nexin 0.003 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0079 0.0388 0.0388
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0123 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.1301 1
Echinococcus multilocularis geminin 0.0169 0.094 0.094
Schistosoma mansoni amine GPCR 0.0079 0.0388 0.0388
Onchocerca volvulus 0.0079 0.0388 0.2628
Echinococcus granulosus glycine receptor subunit alpha 1 0.0066 0.0307 0.0307
Trichomonas vaginalis esterase, putative 0.0036 0.0123 1
Brugia malayi hypothetical protein 0.0079 0.0388 0.043
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0079 0.0388 0.043
Echinococcus granulosus neuropeptide s receptor 0.0566 0.3377 0.3377
Brugia malayi MH2 domain containing protein 0.0119 0.0634 0.0702
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0123 0.0123
Echinococcus multilocularis ribosomal protein S6 kinase delta 1 0.003 0.0091 0.0091
Leishmania major hypothetical protein, conserved 0.0036 0.0123 0.0503
Echinococcus granulosus dro:myosuppressin receptor 0.0079 0.0388 0.0388
Brugia malayi Protein K4 0.0112 0.0594 0.0658
Brugia malayi G-protein coupled receptor 0.0079 0.0388 0.043
Schistosoma mansoni cpg binding protein 0.0032 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Schistosoma mansoni mucolipin 0.0059 0.0269 0.0269
Schistosoma mansoni biogenic amine receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0036 0.0123 0.0295
Echinococcus multilocularis fmrfamide receptor 0.0079 0.0388 0.0388
Schistosoma mansoni nAChR subunit 0.0066 0.0307 0.0307
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0079 0.0388 0.0931
Schistosoma mansoni amine GPCR 0.0079 0.0388 0.0388
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.02 0.02
Echinococcus multilocularis sex peptide receptor 0.0079 0.0388 0.0388
Schistosoma mansoni nAChR subunit 0.0066 0.0307 0.0307
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0035 0.0121 0.0134
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0123 0.0295
Echinococcus multilocularis nAChR subunit 0.0066 0.0307 0.0307
Brugia malayi AKH receptor 0.0079 0.0388 0.043
Brugia malayi PX domain containing protein 0.003 0.0091 0.0101
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0091 0.0101
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0066 0.0307 0.034
Schistosoma mansoni opsin-like receptor 0.0079 0.0388 0.0388
Echinococcus granulosus glycine receptor subunit alpha 1 0.0066 0.0307 0.0307
Echinococcus granulosus glycine receptor subunit beta 0.0066 0.0307 0.0307
Brugia malayi Tachykinin-like peptides receptor 99D 0.0079 0.0388 0.043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0388 0.0388
Brugia malayi follicle stimulating hormone receptor 0.0079 0.0388 0.043
Wolbachia endosymbiont of Brugia malayi cardiolipin synthase 0.0112 0.0594 0.5
Brugia malayi hypothetical protein 0.0079 0.0388 0.043
Loa Loa (eye worm) hypothetical protein 0.0035 0.0121 0.0291
Loa Loa (eye worm) hypothetical protein 0.003 0.0091 0.0219
Brugia malayi ORL1-like opioid receptor 0.0079 0.0388 0.043
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0215 0.1223 0.1223
Schistosoma mansoni amine GPCR 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0036 0.0123 0.0295
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0112 0.0594 0.5
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0066 0.0307 0.0307
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0215 0.1223 0.2937
Loa Loa (eye worm) hypothetical protein 0.0332 0.1943 0.4665
Loa Loa (eye worm) hypothetical protein 0.0035 0.0121 0.0291
Schistosoma mansoni hypothetical protein 0.0079 0.0388 0.0388
Onchocerca volvulus Neuropeptide F receptor homolog 0.0079 0.0388 0.2628
Onchocerca volvulus 0.0079 0.0388 0.2628
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Onchocerca volvulus 0.0079 0.0388 0.2628
Echinococcus multilocularis serotonin receptor 0.0332 0.1943 0.1943
Brugia malayi PXA domain containing protein 0.003 0.0091 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Onchocerca volvulus 0.0079 0.0388 0.2628
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.02 0.0222
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0066 0.0307 0.0307
Echinococcus multilocularis mucolipin 3 0.0065 0.0303 0.0303
Echinococcus granulosus serotonin receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Echinococcus granulosus Phox 0.003 0.0091 0.0091
Echinococcus granulosus neuropeptide Y receptor 0.0079 0.0388 0.0388
Mycobacterium ulcerans beta-lactamase 0.0036 0.0123 0.5
Echinococcus granulosus sex peptide receptor 0.0079 0.0388 0.0388
Echinococcus multilocularis neuropeptide receptor A26 0.0566 0.3377 0.3377
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0066 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Onchocerca volvulus 0.0066 0.0307 0.1917
Brugia malayi Dopamine receptor protein 1 0.0079 0.0388 0.043
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0066 0.0307 0.034
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.02 0.048
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.0049 0.0207 0.0497
Loa Loa (eye worm) ACC-1 protein 0.0066 0.0307 0.0738
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0079 0.0388 0.043
Brugia malayi Dopamine receptor protein 2 0.0079 0.0388 0.043
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0207 0.0229
Loa Loa (eye worm) hypothetical protein 0.0457 0.2712 0.6512
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Echinococcus multilocularis nAChR subunit 0.0035 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0079 0.0388 0.0388
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0066 0.0307 0.0307
Onchocerca volvulus 0.0079 0.0388 0.2628
Schistosoma mansoni neuropeptide f receptor 76f 0.0079 0.0388 0.0388
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0066 0.0307 0.034
Brugia malayi Sorting nexin 12 0.003 0.0091 0.0101
Brugia malayi hypothetical protein 0.003 0.009 0.01
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0066 0.0307 0.0307
Giardia lamblia Hypothetical protein 0.003 0.0091 0.5
Loa Loa (eye worm) hypothetical protein 0.0102 0.0528 0.1268
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Trypanosoma cruzi cardiolipin synthetase, putative 0.0245 0.1408 1
Schistosoma mansoni hypothetical protein 0.0079 0.0388 0.0388
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0123 0.0239
Echinococcus granulosus 7TM GPCR rhodopsin 0.0079 0.0388 0.0388
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0079 0.0388 0.0388
Brugia malayi CXXC zinc finger family protein 0.003 0.0091 0.0101
Echinococcus multilocularis sorting nexin 4 0.003 0.0091 0.0091
Schistosoma mansoni sorting nexin 0.003 0.0091 0.0091
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0066 0.0307 0.034
Loa Loa (eye worm) hypothetical protein 0.0035 0.0121 0.0291
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0079 0.0388 0.0388
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Schistosoma mansoni opsin-like receptor 0.0079 0.0388 0.0388
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.003 0.009 0.01
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Schistosoma mansoni neuropeptide receptor 0.0079 0.0388 0.0388
Onchocerca volvulus 0.0035 0.0121 0.0276
Echinococcus granulosus orexin receptor type 2 0.0079 0.0388 0.0388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Loa Loa (eye worm) hypothetical protein 0.003 0.0091 0.0219
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Onchocerca volvulus 0.0079 0.0388 0.2628
Onchocerca volvulus 0.0215 0.1223 1
Loa Loa (eye worm) TRAF4-associated factor 2 0.003 0.0091 0.0219
Echinococcus granulosus g protein coupled receptor 0.0079 0.0388 0.0388
Echinococcus granulosus peptide allatostatin:somatostatin 0.0079 0.0388 0.0388
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0066 0.0307 0.0738
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0079 0.0388 0.0388
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0066 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Schistosoma mansoni sortingnexin-related 0.003 0.0091 0.0091
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Echinococcus multilocularis neuropeptides capa receptor 0.0079 0.0388 0.0388
Echinococcus multilocularis fmrfamide receptor 0.0079 0.0388 0.0388
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0066 0.0307 0.034
Loa Loa (eye worm) sorting nexin 12 0.003 0.0091 0.0219
Echinococcus granulosus glycine receptor subunit alpha 1 0.0066 0.0307 0.0307
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0066 0.0307 0.0307
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0123 0.0123
Echinococcus multilocularis phospholipase D 0.062 0.3712 0.3712
Brugia malayi hypothetical protein 0.003 0.009 0.01
Loa Loa (eye worm) mucolipin 1 0.0065 0.0303 0.0727
Schistosoma mansoni nAChR subunit 0.003 0.009 0.009
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0079 0.0388 0.0931
Echinococcus granulosus alpha 1A adrenergic receptor 0.0079 0.0388 0.0388
Echinococcus multilocularis cpg binding protein 0.0032 0.0101 0.0101
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0079 0.0388 0.0388
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0123 0.5
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0066 0.0307 0.0307
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0066 0.0307 0.0307
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0112 0.0594 0.1427
Mycobacterium leprae Probable lipase LipE 0.0036 0.0123 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0388 0.0388
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0079 0.0388 0.0388
Brugia malayi hypothetical protein 0.0079 0.0388 0.043
Schistosoma mansoni amine GPCR 0.0079 0.0388 0.0388
Echinococcus multilocularis orexin receptor type 2 0.0079 0.0388 0.0388
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0066 0.0307 0.034
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0123 0.0239
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0035 0.0121 0.0134
Echinococcus granulosus phospholipase D 0.062 0.3712 0.3712
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0066 0.0307 0.034
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Brugia malayi PX domain containing protein 0.003 0.0091 0.0101
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.003 0.009 0.009
Onchocerca volvulus 0.0036 0.0123 0.0289
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0035 0.0121 0.0134
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0035 0.0121 0.0121
Brugia malayi neuropeptide F receptor 0.0079 0.0388 0.043
Brugia malayi TRAF4-associated factor 2 0.003 0.0091 0.0101
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0066 0.0307 0.034
Giardia lamblia Hypothetical protein 0.003 0.0091 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.02 0.02
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0079 0.0388 0.0388
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.003 0.009 0.009
Echinococcus granulosus nAChR subunit 0.0035 0.0121 0.0121
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0132 0.0717 1
Loa Loa (eye worm) G-protein coupled receptor 0.0079 0.0388 0.0931
Echinococcus granulosus geminin 0.0169 0.094 0.094
Loa Loa (eye worm) hypothetical protein 0.0184 0.1037 0.249
Echinococcus multilocularis g protein coupled receptor 0.0079 0.0388 0.0388
Brugia malayi Cation transporter family protein 0.0066 0.0307 0.034
Echinococcus multilocularis neuropeptide receptor 0.0079 0.0388 0.0388
Onchocerca volvulus 0.0079 0.0388 0.2628
Onchocerca volvulus 0.0079 0.0388 0.2628
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0388 0.0388
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0035 0.0121 0.0134
Echinococcus granulosus mucolipin 3 0.0065 0.0303 0.0303
Onchocerca volvulus 0.0079 0.0388 0.2628
Echinococcus granulosus nischarin 0.003 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) PX domain-containing protein 0.003 0.0091 0.0219
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Echinococcus granulosus ribosomal protein S6 kinase delta 1 0.003 0.0091 0.0091
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0912 0.5504 0.5504
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0066 0.0307 0.034
Loa Loa (eye worm) TYRA-2 protein 0.0079 0.0388 0.0931
Brugia malayi hypothetical protein 0.0079 0.0388 0.043
Loa Loa (eye worm) acetylcholine receptor protein 0.003 0.009 0.0217
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0112 0.0594 0.5
Brugia malayi PXA domain containing protein 0.003 0.0091 0.0101
Brugia malayi larval opioid receptor 0.0079 0.0388 0.043
Loa Loa (eye worm) neuropeptide F receptor 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Onchocerca volvulus 0.0079 0.0388 0.2628
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0066 0.0307 0.034
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0123 0.0626
Loa Loa (eye worm) hypothetical protein 0.0036 0.0123 0.0295
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0066 0.0307 0.034
Loa Loa (eye worm) hypothetical protein 0.0036 0.0123 0.0295
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0066 0.0307 0.0738
Brugia malayi beta-lactamase family protein 0.0036 0.0123 0.0136
Brugia malayi PX domain containing protein 0.003 0.0091 0.0101
Brugia malayi hypothetical protein 0.003 0.009 0.01
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0034 0.0111 0.0267
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.02 0.02
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0066 0.0307 0.0307
Entamoeba histolytica phospholipase D, putative 0.0702 0.4215 1
Loa Loa (eye worm) hypothetical protein 0.0132 0.0717 0.1723
Echinococcus granulosus g-protein coupled receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0079 0.0388 0.0388
Echinococcus granulosus biogenic amine 5HT receptor 0.0332 0.1943 0.1943
Onchocerca volvulus 0.0215 0.1223 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0079 0.0388 0.0388
Brugia malayi Phospholipase D. Active site motif family protein 0.0132 0.0717 0.0795
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Echinococcus granulosus hypothetical protein 0.1514 0.9199 0.9199
Loa Loa (eye worm) hypothetical protein 0.0332 0.1943 0.4665
Schistosoma mansoni growth hormone secretagogue receptor 0.0079 0.0388 0.0388
Schistosoma mansoni nAChR subunit 0.003 0.009 0.009
Entamoeba histolytica hypothetical protein 0.0035 0.0121 0.0073
Echinococcus multilocularis 0.003 0.0091 0.0091
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.003 0.0091 0.0091
Toxoplasma gondii ABC1 family protein 0.0036 0.0123 0.0239
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.02 0.02
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Onchocerca volvulus 0.0079 0.0388 0.2628
Schistosoma mansoni nAChR subunit 0.0066 0.0307 0.0307
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Brugia malayi Cation transporter family protein 0.0066 0.0307 0.034
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0066 0.0307 0.034
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0066 0.0307 0.0307
Schistosoma mansoni histamine h1 receptor 0.0079 0.0388 0.0388
Onchocerca volvulus 0.0036 0.0123 0.0289
Schistosoma mansoni cpg binding protein 0.003 0.0091 0.0091
Brugia malayi PX domain containing protein 0.003 0.0091 0.0101
Schistosoma mansoni cpg binding protein 0.0032 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Onchocerca volvulus Putative phospholipase D 0.0132 0.0717 0.5538
Schistosoma mansoni nAChR subunit 0.0066 0.0307 0.0307
Brugia malayi hypothetical protein 0.0079 0.0388 0.043
Echinococcus granulosus G protein coupled receptor 139 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0617 0.3692 0.8866
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0388 0.0388
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0634 0.1522
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0123 1
Loa Loa (eye worm) hypothetical protein 0.059 0.3525 0.8465
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Echinococcus multilocularis sorting nexin 0.003 0.0091 0.0091
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0111 0.0123
Echinococcus multilocularis serotonin receptor 0.0332 0.1943 0.1943
Entamoeba histolytica hypothetical protein 0.0042 0.016 0.0167
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.03 0.03
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0066 0.0307 0.0738
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0066 0.0307 0.034
Onchocerca volvulus 0.0079 0.0388 0.2628
Schistosoma mansoni hypothetical protein 0.0169 0.094 0.094
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0091 0.0218
Echinococcus granulosus tm gpcr rhodopsin 0.0912 0.5504 0.5504
Loa Loa (eye worm) hypothetical protein 0.0035 0.0121 0.0291
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0123 0.0136
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Brugia malayi Serotonin receptor 0.1486 0.9028 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Schistosoma mansoni neurotransmitter gated ion channel 0.0035 0.0121 0.0121
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0079 0.0388 0.0388
Loa Loa (eye worm) neuropeptide F receptor 0.0079 0.0388 0.0931
Onchocerca volvulus 0.0102 0.0528 0.3864
Schistosoma mansoni mucolipin 0.0065 0.0303 0.0303
Brugia malayi beta-lactamase family protein 0.0036 0.0123 0.0136
Echinococcus multilocularis g protein coupled receptor 0.0079 0.0388 0.0388
Brugia malayi excitatory GABA receptor EXP-1A 0.0066 0.0307 0.034
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.0457 0.2712 0.6512
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0079 0.0388 0.0388
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0066 0.0307 0.0307
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0215 0.1223 0.1223
Mycobacterium ulcerans lipase LipD 0.0036 0.0123 0.5
Echinococcus multilocularis sorting nexin 0.003 0.0091 0.0091
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0123 0.0123
Echinococcus multilocularis neuropeptide s receptor 0.0566 0.3377 0.3377
Chlamydia trachomatis phospholipase D superfamily protein 0.0112 0.0594 0.5
Schistosoma mansoni neuropeptide receptor 0.0079 0.0388 0.0388
Brugia malayi G-protein coupled receptor 0.0079 0.0388 0.043
Onchocerca volvulus 0.0066 0.0307 0.1917
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.003 0.009 0.009
Giardia lamblia hypothetical protein 0.003 0.0091 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Loa Loa (eye worm) PXA domain-containing protein 0.003 0.0091 0.0219
Onchocerca volvulus 0.003 0.0091 0.0011
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Echinococcus granulosus cpg binding protein 0.0032 0.0101 0.0101
Echinococcus multilocularis tumor protein p63 0.0694 0.4165 0.4165
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0079 0.0388 0.0388
Echinococcus granulosus tachykinin peptides receptor 99D 0.0079 0.0388 0.0388
Echinococcus granulosus g protein coupled receptor 0.0079 0.0388 0.0388
Echinococcus multilocularis neuropeptide FF receptor 2 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.003 0.0091 0.0219
Schistosoma mansoni neuropeptide F-like receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Echinococcus multilocularis G-protein coupled receptor, putative 0.0079 0.0388 0.0388
Leishmania major cardiolipin synthetase, putative 0.0112 0.0594 0.8035
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0079 0.0388 0.0388
Brugia malayi hypothetical protein 0.0079 0.0388 0.043
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Echinococcus granulosus sorting nexin 6 0.003 0.0091 0.0091
Echinococcus multilocularis neuropeptide receptor 0.0079 0.0388 0.0388
Echinococcus multilocularis neuropeptide Y receptor 0.0079 0.0388 0.0388
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0079 0.0388 0.0388
Brugia malayi GnHR receptor homolog 0.0079 0.0388 0.043
Echinococcus multilocularis glycine receptor subunit beta 0.0066 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) melatonin receptor type 1A 0.0079 0.0388 0.0931
Brugia malayi hypothetical protein 0.0112 0.0594 0.0658
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0245 0.1408 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0123 0.0239
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Echinococcus granulosus neuropeptide receptor 0.0079 0.0388 0.0388
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0112 0.0594 1
Brugia malayi neuropeptide F receptor 0.0079 0.0388 0.043
Brugia malayi putative neuropeptide receptor NPR1 0.0079 0.0388 0.043
Onchocerca volvulus 0.0079 0.0388 0.2628
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0112 0.0594 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Echinococcus multilocularis phospholipase D1 0.0702 0.4215 0.4215
Loa Loa (eye worm) hypothetical protein 0.059 0.3525 0.8465
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0112 0.0594 0.3822
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0079 0.0388 0.0388
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0112 0.0594 0.5
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.003 0.009 0.01
Schistosoma mansoni adenoreceptor 0.0079 0.0388 0.0388
Echinococcus multilocularis somatostatin receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Echinococcus multilocularis nischarin 0.003 0.0091 0.0091
Giardia lamblia Liver stage antigen-like protein 0.003 0.0091 0.5
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0066 0.0307 0.0307
Echinococcus multilocularis glycine receptor subunit beta 0.0066 0.0307 0.0307
Echinococcus multilocularis sorting nexin 6 0.003 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) variant SH3 domain-containing protein 0.003 0.0091 0.0219
Loa Loa (eye worm) beta-lactamase 0.0036 0.0123 0.0295
Schistosoma mansoni hypothetical protein 0.0169 0.094 0.094
Echinococcus granulosus g protein coupled receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) phospholipase D 0.0132 0.0717 0.1723
Echinococcus granulosus sorting nexin 0.003 0.0091 0.0091
Loa Loa (eye worm) PX domain-containing protein 0.003 0.0091 0.0219
Echinococcus granulosus phospholipase D1 0.0702 0.4215 0.4215
Echinococcus granulosus neuropeptide FF receptor 2 0.0079 0.0388 0.0388
Onchocerca volvulus 0.003 0.0091 0.0011
Mycobacterium ulcerans hypothetical protein 0.0036 0.0123 0.5
Schistosoma mansoni neurotransmitter gated ion channel 0.003 0.009 0.009
Loa Loa (eye worm) LGC-31 protein 0.0066 0.0307 0.0738
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Echinococcus multilocularis g-protein coupled receptor 0.0079 0.0388 0.0388
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.003 0.009 0.009
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0123 0.5
Brugia malayi putative neuropeptide receptor 0.0079 0.0388 0.043
Echinococcus multilocularis conserved hypothetical protein 0.1435 0.8715 0.8715
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0123 0.0123
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0112 0.0594 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Brugia malayi Phospholipase d protein 1 0.0702 0.4215 0.4668
Schistosoma mansoni acetylcholine receptor-related 0.003 0.009 0.009
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0079 0.0388 0.0388
Brugia malayi RE15519p 0.0079 0.0388 0.043
Echinococcus granulosus neuropeptide receptor A26 0.0566 0.3377 0.3377
Brugia malayi PX domain containing protein 0.003 0.0091 0.0101
Echinococcus granulosus fmrfamide receptor 0.0079 0.0388 0.0388
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0123 1
Echinococcus multilocularis g protein coupled receptor 0.0079 0.0388 0.0388
Brugia malayi hypothetical protein 0.003 0.009 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0388 0.0388
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0079 0.0388 0.0388
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0035 0.0121 0.0291
Schistosoma mansoni opsin-like receptor 0.0079 0.0388 0.0388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0388 0.0388
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0079 0.0388 0.0931
Entamoeba histolytica phospholipase D active site domain-containing protein 0.059 0.3525 0.8326
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0035 0.0121 0.0121
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.003 0.0091 0.0219
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0066 0.0307 0.0307
Echinococcus granulosus tm gpcr rhodopsin 0.0079 0.0388 0.0388
Onchocerca volvulus Putative nachr subunit 0.0066 0.0307 0.1917
Brugia malayi G protein-coupled receptor 0.0079 0.0388 0.043
Schistosoma mansoni biogenic amine (5HT) receptor 0.1644 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0066 0.0307 0.0307
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0066 0.0307 0.0307
Echinococcus multilocularis allatostatin A receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0035 0.0121 0.0291
Chlamydia trachomatis phospholipase D endonuclease family protein 0.0112 0.0594 0.5
Loa Loa (eye worm) hypothetical protein 0.0215 0.1223 0.2937
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0066 0.0307 0.0307
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.003 0.009 0.009
Echinococcus multilocularis Phox 0.003 0.0091 0.0091
Echinococcus granulosus tm gpcr rhodopsin 0.0079 0.0388 0.0388
Schistosoma mansoni hypothetical protein 0.0034 0.0111 0.0111
Brugia malayi hypothetical protein 0.0079 0.0388 0.043
Echinococcus multilocularis dro:myosuppressin receptor 0.0079 0.0388 0.0388
Trypanosoma brucei cardiolipin synthetase 0.0245 0.1408 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0388 0.0388
Brugia malayi Dopamine receptor 0.0079 0.0388 0.043
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0079 0.0388 0.0931
Echinococcus granulosus glycine receptor subunit beta 0.0066 0.0307 0.0307
Echinococcus granulosus neuropeptide receptor 0.0079 0.0388 0.0388
Schistosoma mansoni biogenic amine (5HT) receptor 0.0332 0.1943 0.1943
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0066 0.0307 0.0738
Loa Loa (eye worm) hypothetical protein 0.0036 0.0123 0.0295
Schistosoma mansoni cellular tumor antigen P53 0.0102 0.0528 0.0528
Schistosoma mansoni phospholipase D 0.0702 0.4215 0.4215
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0694 0.4164 0.4164
Onchocerca volvulus 0.0079 0.0388 0.2628
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.003 0.009 0.01
Plasmodium vivax cardiolipin synthetase, putative 0.0112 0.0594 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Trypanosoma brucei cardiolipin synthetase, putative 0.0245 0.1408 1
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0112 0.0594 0.0594
Echinococcus granulosus allatostatin A receptor 0.0079 0.0388 0.0388
Brugia malayi hypothetical protein 0.0079 0.0388 0.043
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Brugia malayi Melatonin receptor type 1A 0.0079 0.0388 0.043
Echinococcus multilocularis phospholipase d3 0.0132 0.0717 0.0717
Brugia malayi hypothetical protein 0.0079 0.0388 0.043
Echinococcus multilocularis G protein coupled receptor 139 0.0079 0.0388 0.0388
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0123 1
Schistosoma mansoni nAChR subunit 0.0066 0.0307 0.0307
Schistosoma mansoni acetylcholine receptor subunit beta 0.003 0.009 0.009
Echinococcus multilocularis neuropeptide Y receptor 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Echinococcus granulosus sorting nexin 13 0.003 0.0091 0.0091
Onchocerca volvulus 0.0079 0.0388 0.2628
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0066 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Brugia malayi G protein-coupled receptor F59B2.13 0.0079 0.0388 0.043
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Onchocerca volvulus 0.0035 0.0121 0.0276
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0079 0.0388 0.0388
Echinococcus granulosus tumor protein p63 0.0694 0.4165 0.4165
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Brugia malayi Serotonin receptor 0.0079 0.0388 0.043
Onchocerca volvulus 0.0215 0.1223 1
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0123 1
Loa Loa (eye worm) hypothetical protein 0.0694 0.4164 1
Onchocerca volvulus 0.003 0.0091 0.0006
Brugia malayi Coelomocyte uptake defective protein 5 0.0065 0.0303 0.0335
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0694 0.4164 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Echinococcus granulosus 7tm_1 domain containing protein 0.0079 0.0388 0.0388
Giardia lamblia Hypothetical protein 0.003 0.0091 0.5
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0258 0.1264
Schistosoma mansoni neuropeptide receptor 0.0079 0.0388 0.0388
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0079 0.0388 0.043
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1644 1 1
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0066 0.0307 0.034
Brugia malayi Cation transporter family protein 0.0215 0.1223 0.1354
Loa Loa (eye worm) GABA receptor subunit 0.0035 0.0121 0.0291
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0207 0.0229
Chlamydia trachomatis phospholipase D superfamily protein 0.0112 0.0594 0.5
Onchocerca volvulus 0.0066 0.0307 0.1917
Schistosoma mansoni nAChR subunit 0.0066 0.0307 0.0307
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0066 0.0307 0.034
Echinococcus granulosus phospholipase d3 0.0132 0.0717 0.0717
Brugia malayi hypothetical protein 0.003 0.009 0.01
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.003 0.009 0.0217
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0388 0.0388
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0079 0.0388 0.2628
Loa Loa (eye worm) hypothetical protein 0.0079 0.0388 0.0931
Echinococcus granulosus neuropeptide Y receptor 0.0079 0.0388 0.0388
Echinococcus granulosus sorting nexin 2 0.003 0.0091 0.0091
Brugia malayi Phospholipase D. Active site motif family protein 0.0245 0.1408 0.1559
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0066 0.0307 0.0307
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0207 0.0497
Schistosoma mansoni amine GPCR 0.0423 0.2502 0.2502
Loa Loa (eye worm) hypothetical protein 0.0035 0.0121 0.0291
Loa Loa (eye worm) hypothetical protein 0.0035 0.0121 0.0291
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0079 0.0388 0.0388
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0066 0.0307 0.0307
Echinococcus multilocularis sorting nexin 14 0.003 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Loa Loa (eye worm) ACC-1 protein 0.0066 0.0307 0.0738
Schistosoma mansoni neuropeptide F-like receptor 0.0079 0.0388 0.0388
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0079 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0066 0.0307 0.0738
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0066 0.0307 0.034
Schistosoma mansoni sorting nexin 0.003 0.0091 0.0091
Schistosoma mansoni sorting nexin 0.003 0.0091 0.0091
Giardia lamblia Hypothetical protein 0.003 0.0091 0.5
Echinococcus granulosus sorting nexin 4 0.003 0.0091 0.0091
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.003 0.009 0.01
Schistosoma mansoni myosin xvIII 0.0079 0.0388 0.0388
Echinococcus multilocularis neuropeptides capa receptor 0.0079 0.0388 0.0388
Echinococcus granulosus sorting nexin 14 0.003 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0217
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.003 0.009 0.01
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0079 0.0388 0.0388

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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