Detailed information for compound 1697470

Basic information

Technical information
  • TDR Targets ID: 1697470
  • Name: [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltride cyl)chroman-6-yl] (2E,4E,6E,8E)-3,7-dimethyl- 9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6, 8-tetraenoate
  • MW: 713.126 | Formula: C49H76O3
  • H donors: 0 H acceptors: 1 LogP: 16.95 Rotable bonds: 19
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(CCCC1(C)CCc2c(O1)c(C)c(c(c2C)OC(=O)/C=C(/C=C/C=C(/C=C/C1=C(C)CCCC1(C)C)\C)\C)C)CCCC(CCCC(C)C)C
  • InChi: 1S/C49H76O3/c1-34(2)19-14-20-35(3)21-15-22-36(4)25-17-31-49(13)32-29-43-42(10)46(40(8)41(9)47(43)52-49)51-45(50)33-38(6)24-16-23-37(5)27-28-44-39(7)26-18-30-48(44,11)12/h16,23-24,27-28,33-36H,14-15,17-22,25-26,29-32H2,1-13H3/b24-16+,28-27+,37-23+,38-33+
  • InChiKey: RIQIJXOWVAHQES-BUXFCOQUSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl] 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoate
  • 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] ester
  • (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] ester
  • 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl] ester
  • (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl] ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.019 0.0106
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0024 0.002
Schistosoma mansoni cpg binding protein 0.0058 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0444 0.5318 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.019 0.0106
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0024 0.002
Brugia malayi CXXC zinc finger family protein 0.0058 0.0608 0.2099
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0059 0.0888
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0118 0.0114
Echinococcus granulosus cpg binding protein 0.0061 0.0648 0.0645
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0059 0.0888
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0059 0.0888
Plasmodium falciparum cysteine protease ATG4, putative 0.0023 0.0183 0.3121
Echinococcus multilocularis GPCR, family 2 0.0016 0.0092 0.0089
Echinococcus granulosus geminin 0.0172 0.1999 0.1997
Brugia malayi beta-NAC-like protein 0.0036 0.0332 0.1108
Echinococcus multilocularis transcription factor btf3 0.0036 0.0332 0.0329
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.006 0.063 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.1028 0.1025
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0525 0.0522
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0525 0.8329
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.019 0.1502
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0024 0.002
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0787 0.0787
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0787 0.0784
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0525 0.7654
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.006 0.063 1
Loa Loa (eye worm) hypothetical protein 0.006 0.063 0.1145
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0059 0.0888
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0525 0.7654
Schistosoma mansoni survival motor neuron protein 0.0049 0.0491 0.0491
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0525 0.0522
Loa Loa (eye worm) hypothetical protein 0.0124 0.1417 0.2633
Schistosoma mansoni thyroid hormone receptor 0.001 0.0024 0.0024
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0024 0.002
Entamoeba histolytica hypothetical protein 0.0073 0.0787 1
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.006 0.063 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.019 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0024 0.002
Echinococcus multilocularis geminin 0.0172 0.1999 0.1997
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0059 0.0888
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0525 0.7654
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0608 0.1103
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0059 0.0888
Schistosoma mansoni thyroid hormone receptor 0.001 0.0024 0.0024
Echinococcus granulosus FTZ F1 alpha 0.001 0.0024 0.002
Onchocerca volvulus Phospholipase A2 homolog 0.0093 0.1039 0.1918
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0024 0.002
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0525 0.0522
Loa Loa (eye worm) ICD-1 protein 0.0036 0.0332 0.0582
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0175
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0525 0.0522
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.1403 0.1403
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0092 0.0089
Echinococcus granulosus transcription factor btf3 0.0036 0.0332 0.0329
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.019 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1028 0.1028
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.006 0.063 1
Echinococcus granulosus GPCR family 2 0.0016 0.0092 0.0089
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Brugia malayi hypothetical protein 0.0238 0.2806 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.005 0.0511 0.0921
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0332 0.3326
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0525 0.7654
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0092 0.0089
Entamoeba histolytica hypothetical protein 0.0073 0.0787 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0175
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0317 0.1056
Echinococcus multilocularis cpg binding protein 0.0061 0.0648 0.0645
Treponema pallidum bacterioferrin (TpF1) 0.0009 0.0003 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0332 0.5245
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0059 0.0888
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0092 0.013
Onchocerca volvulus 0.0049 0.0491 0.0884
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.2806 0.2804
Onchocerca volvulus Huntingtin homolog 0.0124 0.1417 0.2633
Echinococcus multilocularis cysteine protease atg4b 0.006 0.063 0.0626
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0116 0.5
Echinococcus granulosus tm gpcr rhodopsin 0.0827 0.9987 0.9987
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0092 0.0089
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0024 0.002
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0118 0.0178
Trichomonas vaginalis helicase, putative 0.0013 0.0059 0.0888
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0175
Schistosoma mansoni apoferritin-2 0.0009 0.0003 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1028 0.1028
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0024 0.002
Echinococcus granulosus Peptidase C54 0.006 0.063 0.0626
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0525 0.0947
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0059 0.0888
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0525 0.7654
Loa Loa (eye worm) hypothetical protein 0.0124 0.1417 0.2633
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0059 0.0888
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.1028 0.1897
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0059 0.0888
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0024 0.002
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.006 0.063 0.063
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.019 0.0143
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0525 0.0525
Loa Loa (eye worm) hypothetical protein 0.0024 0.019 0.0314
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0116 0.0908
Brugia malayi hypothetical protein 0.0073 0.0787 0.2743
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0024 0.0024
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0116 0.6047
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0491 0.1681
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0024 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.019 0.0314
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.1028 0.1025
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0511 0.1753
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.1028 0.1025
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0024 0.0024
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.019 0.0143
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0525 0.3225
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0787 0.0784
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0024 0.002
Schistosoma mansoni ferritin 0.0009 0.0003 0.0003
Schistosoma mansoni ferritin 0.0009 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0175
Schistosoma mansoni hypothetical protein 0.0828 1 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.0074 0.0071
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0059 0.0888
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0525 0.8329
Schistosoma mansoni cpg binding protein 0.0061 0.0648 0.0648
Trypanosoma brucei protein kinase, putative 0.0051 0.0525 0.7654
Onchocerca volvulus Huntingtin homolog 0.0124 0.1417 0.2633
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.019 0.1502
Schistosoma mansoni coup transcription factor 0.001 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0093 0.1039 0.1918
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.1028 0.3609
Schistosoma mansoni hypothetical protein 0.0073 0.0787 0.0787
Trypanosoma brucei transcription factor BTF3, putative 0.0036 0.0332 0.3326
Entamoeba histolytica transcription factor BTF3, putative 0.0036 0.0332 0.2459
Entamoeba histolytica hypothetical protein 0.0073 0.0787 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0059 0.0888
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0024 0.002
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0024 0.002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0511 0.0921
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.006 0.063 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.011 0.1242 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0525 0.7654
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0009 0.0003 0.5
Schistosoma mansoni ferritin 0.0009 0.0003 0.0003
Mycobacterium ulcerans hypothetical protein 0.0024 0.019 0.1502
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.019 0.1502
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.006 0.063 1
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0332 0.3326
Loa Loa (eye worm) hypothetical protein 0.0024 0.019 0.0314
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0024 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0059 0.0888
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0024 0.0024
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.019 0.1502
Entamoeba histolytica peptidase, C54 family 0.006 0.063 0.7394
Schistosoma mansoni transcription factor btf3 0.0036 0.0332 0.0332
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.006 0.063 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.019 0.1502
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0104 0.5408
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.019 0.0143
Onchocerca volvulus 0.0024 0.019 0.0314
Echinococcus multilocularis Peptidase C54 0.006 0.063 0.0626
Brugia malayi AMP-binding enzyme family protein 0.0024 0.019 0.0597
Toxoplasma gondii NAC domain-containing protein 0.0036 0.0332 0.1401
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0024 0.0024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0024 0.0024
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.019 0.1502
Loa Loa (eye worm) hypothetical protein 0.0018 0.0116 0.0175
Schistosoma mansoni ferritin 0.0009 0.0003 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0024 0.002
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.006 0.063 1
Onchocerca volvulus Phospholipase A2 homolog 0.0444 0.5318 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0317 0.0555
Entamoeba histolytica hypothetical protein 0.0073 0.0787 1
Schistosoma mansoni hypothetical protein 0.0049 0.0491 0.0491
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0827 0.9987 0.9987
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0059 0.0888
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0525 0.8329
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0332 0.5245
Echinococcus multilocularis dnaJ subfamily B 0.0828 1 1
Echinococcus granulosus cysteine protease atg4b 0.006 0.063 0.0626
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.019 0.0106
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0118 0.0114
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0525 0.7654
Brugia malayi Phospholipase A2 family protein 0.0093 0.1039 0.365
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0059 0.0888
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0092 0.0247
Schistosoma mansoni nuclear hormone receptor 0.001 0.0024 0.0024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.019 1
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0092 0.0247
Schistosoma mansoni ferritin light chain 0.0009 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0036 0.0332 0.2459
Brugia malayi AMP-binding enzyme family protein 0.0024 0.019 0.0597
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.0074 0.0071
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.2806 0.2804
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.019 1
Plasmodium vivax basic transcription factor 3b, putative 0.0036 0.0332 1
Brugia malayi MAP kinase sur-1 0.0051 0.0525 0.1801
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0525 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0332 0.5245
Loa Loa (eye worm) hypothetical protein 0.0016 0.0092 0.013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0104 0.5408
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0525 0.8329
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.019 0.1502
Schistosoma mansoni cpg binding protein 0.0061 0.0648 0.0648
Brugia malayi AMP-binding enzyme family protein 0.0024 0.019 0.0597
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0092 0.0089
Onchocerca volvulus 0.0058 0.0608 0.1103
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0104 0.5408
Schistosoma mansoni apoferritin-2 0.0009 0.0003 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0024 0.002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0059 0.0888
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.1028 0.1025
Brugia malayi hypothetical protein 0.0124 0.1417 0.5009
Plasmodium falciparum basic transcription factor 3b, putative 0.0036 0.0332 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0059 0.0888
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0024 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1028 0.1028
Schistosoma mansoni hypothetical protein 0.0172 0.1999 0.1999
Mycobacterium ulcerans hypothetical protein 0.011 0.1245 1
Loa Loa (eye worm) hypothetical protein 0.0238 0.2806 0.5256
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0511 0.1753
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0024 0.0024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0104 0.5408
Schistosoma mansoni hypothetical protein 0.0034 0.0317 0.0317
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0074 0.0071
Schistosoma mansoni ferritin light chain 0.0009 0.0003 0.0003
Schistosoma mansoni autophagin-1 (C54 family) 0.006 0.063 0.063
Leishmania major basic transcription factor 3a, putative 0.0036 0.0332 0.3326
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0024 0.002
Schistosoma mansoni hypothetical protein 0.0172 0.1999 0.1999
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0074 0.0074
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0074 0.0071
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0115 0.0328
Brugia malayi Peptidase family C54 containing protein 0.006 0.063 0.2178
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.006 0.063 0.063
Schistosoma mansoni hypothetical protein 0.0062 0.066 0.066

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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