Detailed information for compound 1719182

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 253.224 | Formula: C9H11FN6O2
  • H donors: 0 H acceptors: 5 LogP: 0.25 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: [18F]CCn1nnc(c1)Cn1c(C)cnc1[N+](=O)[O-]
  • InChi: 1S/C9H11FN6O2/c1-7-4-11-9(16(17)18)15(7)6-8-5-14(3-2-10)13-12-8/h4-5H,2-3,6H2,1H3/i10-1
  • InChiKey: YSZBTBOQNVASGA-LMANFOLPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0676 0.1434
Loa Loa (eye worm) hypothetical protein 0.0038 0.0269 0.0542
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0052 0.0466 0.3515
Onchocerca volvulus 0.0038 0.0269 0.0184
Loa Loa (eye worm) hypothetical protein 0.0052 0.0466 0.0974
Brugia malayi glutathione reductase 0.005 0.0437 0.081
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.004 0.0293 0.0293
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.004 0.0293 0.2081
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0113 0.1326 1
Loa Loa (eye worm) RNA binding protein 0.0067 0.0676 0.1434
Trichomonas vaginalis esterase, putative 0.0038 0.0269 0.0826
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0113 0.1326 0.4069
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0676 0.0676
Brugia malayi Peptidase family M1 containing protein 0.004 0.0293 0.053
Mycobacterium ulcerans beta-lactamase 0.0038 0.0269 0.2029
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0283 0.0868
Giardia lamblia CCR4-NOT transcription complex, subunit 7 0.002 0.0022 0.5
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0251 0.0795
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0073 0.0766 0.0766
Mycobacterium ulcerans aminopeptidase N PepN 0.004 0.0293 0.2211
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0269 0.0852
Leishmania major trypanothione reductase 0.005 0.0437 0.3183
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0676 0.1434
Onchocerca volvulus 0.0052 0.0466 0.0581
Brugia malayi RNA binding protein 0.0067 0.0676 0.1277
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0177 0.375
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.004 0.0293 0.2081
Brugia malayi Pre-SET motif family protein 0.0219 0.283 0.5483
Plasmodium falciparum M1-family alanyl aminopeptidase 0.004 0.0293 0.0797
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0269 0.1896
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0469 0.0469
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0113 0.1326 0.4069
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0078 0.0842 0.0842
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0437 0.1384
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0177 0.0177
Loa Loa (eye worm) leukotriene A4 hydrolase 0.004 0.0293 0.0595
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0283 0.0868
Echinococcus multilocularis CCR4 NOT transcription complex subunit 7 0.002 0.0022 0.0022
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0113 0.1326 0.1326
Loa Loa (eye worm) hypothetical protein 0.0052 0.0469 0.0981
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0676 0.0676
Brugia malayi hypothetical protein 0.004 0.0293 0.053
Loa Loa (eye worm) hypothetical protein 0.0052 0.0466 0.0974
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0269 0.0852
Brugia malayi hypothetical protein 0.0159 0.1981 0.3827
Echinococcus granulosus tumor protein p63 0.0355 0.476 0.476
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0269 0.5956
Loa Loa (eye worm) hypothetical protein 0.0038 0.0269 0.0542
Mycobacterium leprae Probable lipase LipE 0.0038 0.0269 0.1773
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0283 0.2002
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0113 0.1326 0.1326
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0251 0.0795
Trypanosoma cruzi Aminopeptidase M1, putative 0.0113 0.1326 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0052 0.0466 0.3071
Treponema pallidum bacterioferrin (TpF1) 0.0019 0 0.5
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.004 0.0293 0.2081
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0073 0.0766 0.5706
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0113 0.1326 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0269 0.0542
Echinococcus granulosus aminopeptidase N 0.0382 0.5143 0.5143
Loa Loa (eye worm) hypothetical protein 0.0038 0.0269 0.0542
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0225 0.0714
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.004 0.0293 0.2081
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0437 0.0437
Trypanosoma brucei Aminopeptidase M1, putative 0.0113 0.1326 1
Schistosoma mansoni hypothetical protein 0.0078 0.0842 0.0842
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0113 0.1326 1
Entamoeba histolytica hypothetical protein 0.0078 0.0842 0.6289
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.004 0.0293 0.6538
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0269 0.0826
Onchocerca volvulus 0.0159 0.1981 0.3633
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0281 0.2117
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.1338 0.424
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0113 0.1326 0.1326
Schistosoma mansoni transcription factor LCR-F1 0.0078 0.0842 0.0842
Trypanosoma cruzi aminopeptidase, putative 0.0113 0.1326 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.1517 1
Trypanosoma cruzi aminopeptidase, putative 0.004 0.0293 0.2081
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0269 0.0483
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0113 0.1326 0.1326
Loa Loa (eye worm) beta-lactamase 0.0038 0.0269 0.0542
Brugia malayi Inositol-1 0.0039 0.0283 0.051
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0113 0.1326 0.1326
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0052 0.0466 0.3515
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0283 0.0283
Toxoplasma gondii ABC1 family protein 0.0038 0.0269 0.5956
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0177 0.0177
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0466 0.3515
Mycobacterium ulcerans aminopeptidase N PepN 0.0113 0.1326 1
Giardia lamblia CCR4-NOT transcription complex, subunit 7 0.002 0.0022 0.5
Echinococcus multilocularis microtubule associated protein 2 0.0725 1 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0177 0.0177
Echinococcus multilocularis tumor protein p63 0.0355 0.476 0.476
Brugia malayi Peptidase family M1 containing protein 0.0382 0.5143 1
Entamoeba histolytica hypothetical protein 0.0078 0.0842 0.6289
Onchocerca volvulus 0.0038 0.0269 0.0184
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.004 0.0293 0.09
Plasmodium vivax SET domain protein, putative 0.0031 0.0177 0.375
Mycobacterium ulcerans hypothetical protein 0.0052 0.0466 0.3515
Loa Loa (eye worm) hypothetical protein 0.0343 0.4583 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0225 0.1485
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0219 0.283 0.6156
Plasmodium vivax acyl-CoA synthetase, putative 0.0039 0.0281 0.6238
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.1338 0.424
Echinococcus multilocularis aminopeptidase N 0.0382 0.5143 0.5143
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0113 0.1326 1
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0676 0.1277
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0269 0.1896
Echinococcus granulosus puromycin sensitive aminopeptidase 0.004 0.0293 0.0293
Entamoeba histolytica aminopeptidase, putative 0.0113 0.1326 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.1338 0.882
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.1432 0.3092
Onchocerca volvulus 0.0382 0.5143 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0113 0.1326 0.1326
Toxoplasma gondii aminopeptidase n, putative 0.004 0.0293 0.6538
Entamoeba histolytica acyl-coA synthetase, putative 0.0052 0.0466 0.3406
Trichomonas vaginalis CCR4-associated factor, putative 0.002 0.0022 0.0067
Echinococcus granulosus tar DNA binding protein 0.0067 0.0676 0.0676
Schistosoma mansoni ccr4-associated factor 0.002 0.0022 0.0022
Loa Loa (eye worm) aminopeptidase N 0.0113 0.1326 0.2859
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0251 0.0795
Loa Loa (eye worm) hypothetical protein 0.0039 0.0281 0.0568
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0177 0.0177
Brugia malayi beta-lactamase family protein 0.0038 0.0269 0.0483
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0161 0.0161
Mycobacterium tuberculosis Conserved protein 0.0038 0.0269 0.0852
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0269 0.0852
Loa Loa (eye worm) glutathione reductase 0.005 0.0437 0.091
Plasmodium vivax glutathione reductase, putative 0.005 0.0437 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0283 0.2002
Brugia malayi beta-lactamase family protein 0.0038 0.0269 0.0483
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0466 0.0867
Loa Loa (eye worm) hypothetical protein 0.0039 0.0281 0.0568
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0283 0.2002
Plasmodium falciparum glutathione reductase 0.005 0.0437 1
Onchocerca volvulus 0.0249 0.3257 0.6203
Loa Loa (eye worm) hypothetical protein 0.0039 0.0281 0.0568
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0113 0.1326 0.1326
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0466 0.3406
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0039 0.0281 0.5
Trichomonas vaginalis CCR4-associated factor, putative 0.002 0.0022 0.0067
Loa Loa (eye worm) hypothetical protein 0.027 0.355 0.7736
Plasmodium falciparum thioredoxin reductase 0.005 0.0437 1
Toxoplasma gondii aminopeptidase N protein 0.004 0.0293 0.6538
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0251 0.0795
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0466 0.0867
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0113 0.1326 0.1326
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0437 0.0437
Schistosoma mansoni aminopeptidase A (M01 family) 0.004 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.004 0.0293 0.0595
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0466 0.0867
Loa Loa (eye worm) hypothetical protein 0.0039 0.0281 0.0568
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.0341
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0269 0.0852
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0283 0.2002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0281 0.0568
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0113 0.1326 0.1326
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0466 0.3406
Brugia malayi Peptidase family M1 containing protein 0.0113 0.1326 0.2546
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.1432 0.3092
Loa Loa (eye worm) hypothetical protein 0.0052 0.0466 0.0974
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0242 0.3156 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0052 0.0466 0.3515
Onchocerca volvulus 0.0038 0.0269 0.0184
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0283 1
Trichomonas vaginalis set domain proteins, putative 0.0249 0.3257 1
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0113 0.1326 0.1326
Echinococcus granulosus CCR4 NOT transcription complex subunit 7 0.002 0.0022 0.0022
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0113 0.1326 0.1326
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0177 0.0177
Schistosoma mansoni inositol monophosphatase 0.0039 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0073 0.0766 0.1631
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0052 0.0466 0.3071
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.1338 0.424
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0466 0.1476
Leishmania major hypothetical protein, conserved 0.0038 0.0269 0.1896
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0283 0.2133
Brugia malayi hypothetical protein 0.0113 0.1326 0.2546
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0283 0.0283
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.004 0.0293 0.6538
Echinococcus multilocularis leukotriene A 4 hydrolase 0.004 0.0293 0.0293
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0269 0.0826
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.0466 0.3515
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0177 0.0177
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0676 0.0676
Mycobacterium tuberculosis Conserved protein 0.0038 0.0269 0.0852
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0073 0.0766 0.0766
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.004 0.0293 0.2081
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.004 0.0293 0.0797
Loa Loa (eye worm) hypothetical protein 0.0038 0.0269 0.0542
Onchocerca volvulus 0.0052 0.0469 0.0587
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0466 0.3406
Brugia malayi TATA binding protein associated factor 0.004 0.0293 0.053
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0269 0.0826
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0676 0.0676
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0269 0.1773
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.004 0.0293 0.2081
Mycobacterium ulcerans lipase LipD 0.0038 0.0269 0.2029
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.1338 0.424
Mycobacterium ulcerans hypothetical protein 0.0038 0.0269 0.2029
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0437 0.091
Loa Loa (eye worm) TATA binding protein associated factor 0.004 0.0293 0.0595
Toxoplasma gondii aminopeptidase N, putative 0.004 0.0293 0.6538
Schistosoma mansoni inositol monophosphatase 0.0039 0.0283 0.0283
Entamoeba histolytica hypothetical protein 0.0078 0.0842 0.6289
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0269 0.0269
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0269 0.2029
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.1338 0.424
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.1517 0.4808
Brugia malayi hypothetical protein 0.0078 0.0842 0.1601
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0177 0.0177
Schistosoma mansoni microtubule-associated protein tau 0.0725 1 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0293 0.0595
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0269 0.0269
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.1517 0.4808
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0466 0.3406
Brugia malayi beta-lactamase 0.0038 0.0269 0.0483
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0052 0.0466 0.1476
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0676 0.0676
Mycobacterium tuberculosis Probable reductase 0.0113 0.1338 0.424
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0073 0.0766 0.1631
Loa Loa (eye worm) hypothetical protein 0.0038 0.0269 0.0542
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0078 0.0842 0.0842
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0676 0.0676
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0269 0.0852
Echinococcus granulosus puromycin sensitive aminopeptidase 0.004 0.0293 0.0293
Brugia malayi Thioredoxin reductase 0.005 0.0437 0.081
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0437 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0269 0.0852
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0269 0.1896
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0437 0.3183
Loa Loa (eye worm) inositol-1 0.0039 0.0283 0.0572
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0269 0.2029
Echinococcus granulosus leukotriene A 4 hydrolase 0.004 0.0293 0.0293
Trypanosoma brucei trypanothione reductase 0.005 0.0437 0.3183
Toxoplasma gondii thioredoxin reductase 0.005 0.0437 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0269 0.0826
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0283 0.0868
Entamoeba histolytica hypothetical protein 0.0078 0.0842 0.6289
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0466 0.3515
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0113 0.1326 0.1326
Brugia malayi TAR-binding protein 0.0067 0.0676 0.1277
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0283 0.2002
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0466 0.3406
Brugia malayi Pre-SET motif family protein 0.0031 0.0177 0.0304
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.1517 0.4808
Trypanosoma brucei aminopeptidase, putative 0.004 0.0293 0.2081
Onchocerca volvulus 0.0113 0.1326 0.2312
Mycobacterium tuberculosis Conserved protein 0.0038 0.0269 0.0852
Loa Loa (eye worm) hypothetical protein 0.004 0.0293 0.0595
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0269 0.0542
Loa Loa (eye worm) peptidase family M1 containing protein 0.0309 0.411 0.8964
Loa Loa (eye worm) hypothetical protein 0.0159 0.1981 0.4296
Onchocerca volvulus 0.004 0.0293 0.0233
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.004 0.0293 0.0293
Trypanosoma brucei Aminopeptidase M1, putative 0.0113 0.1326 1
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0269 0.0826
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0283 0.6289
Brugia malayi MH2 domain containing protein 0.012 0.1432 0.2754
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0466 0.3515
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0269 0.0269
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0269 0.0852
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0039 0.0281 0.089

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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