Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | opsin-like receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | amine GPCR | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | amine GPCR | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | serotonin receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.2931 | 0.2931 |
Schistosoma mansoni | biogenic amine receptor | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | allatostatin A receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0046 | 0.823 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0023 | 0.2931 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Brugia malayi | Dopamine receptor protein 1 | 0.0046 | 0.823 | 0.823 |
Brugia malayi | AKH receptor | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | opsin-like receptor | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | amine GPCR | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | amine GPCR | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | fmrfamide receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0046 | 0.823 | 0.5 |
Echinococcus multilocularis | somatostatin receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Brugia malayi | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | fmrfamide receptor | 0.0046 | 0.823 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0046 | 0.823 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0014 | 0.0891 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0034 | 0.5535 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0014 | 0.0891 | 0.5 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0014 | 0.0891 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0014 | 0.0891 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.823 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0023 | 0.2931 | 1 |
Schistosoma mansoni | cytochrome P450 | 0.0014 | 0.0891 | 0.1082 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0037 | 0.61 | 0.61 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0046 | 0.823 | 1 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0046 | 0.823 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | somatostatin receptor | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0014 | 0.0891 | 0.1082 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0046 | 0.823 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.2931 | 0.2931 |
Schistosoma mansoni | adenoreceptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | cytochrome P450 | 0.0014 | 0.0891 | 0.0891 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | Serotonin receptor | 0.0046 | 0.823 | 0.823 |
Brugia malayi | ORL1-like opioid receptor | 0.0046 | 0.823 | 0.823 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0014 | 0.0891 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0014 | 0.0891 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0046 | 0.823 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0014 | 0.0891 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0046 | 0.823 | 1 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Brugia malayi | G protein-coupled receptor | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0014 | 0.0891 | 0.5 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0014 | 0.0891 | 0.5 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.2931 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | myosin xvIII | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | serotonin receptor | 0.0046 | 0.823 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.2931 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Brugia malayi | neuropeptide F receptor | 0.0046 | 0.823 | 0.823 |
Brugia malayi | Serotonin receptor | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0046 | 0.823 | 0.823 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0046 | 0.823 | 0.823 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Brugia malayi | putative neuropeptide receptor | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0891 | 0.1082 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.823 | 1 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0037 | 0.61 | 0.7413 |
Brugia malayi | G-protein coupled receptor | 0.0046 | 0.823 | 0.823 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0014 | 0.0891 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.2931 | 0.2931 |
Schistosoma mansoni | neuropeptide receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Brugia malayi | sulfakinin receptor protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Mycobacterium leprae | putative cytochrome p450 | 0.0014 | 0.0891 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.004 | 0.6889 | 0.8371 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0014 | 0.0891 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0046 | 0.823 | 1 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Echinococcus multilocularis | sex peptide receptor | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0023 | 0.2931 | 0.2931 |
Echinococcus multilocularis | serotonin receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0046 | 0.823 | 0.823 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0014 | 0.0891 | 0.5 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Echinococcus multilocularis | neuropeptide receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0014 | 0.0891 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0046 | 0.823 | 0.823 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0014 | 0.0891 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | amine GPCR | 0.0046 | 0.823 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0023 | 0.2931 | 1 |
Echinococcus granulosus | allatostatin A receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Brugia malayi | larval opioid receptor | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | voltage-gated potassium channel | 0.004 | 0.6889 | 0.8371 |
Echinococcus multilocularis | fmrfamide receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.0046 | 0.823 | 0.823 |
Brugia malayi | neuropeptide F receptor | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0046 | 0.823 | 1 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0037 | 0.61 | 0.61 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0014 | 0.0891 | 0.5 |
Brugia malayi | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.4966 | 0.4966 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0046 | 0.823 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0014 | 0.0891 | 0.5 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0014 | 0.0891 | 0.0891 |
Schistosoma mansoni | neuropeptide receptor | 0.0046 | 0.823 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0014 | 0.0891 | 0.5 |
Echinococcus multilocularis | 0.0014 | 0.0891 | 0.1082 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0046 | 0.823 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0046 | 0.823 | 0.823 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0046 | 0.823 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0046 | 0.823 | 0.823 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0014 | 0.0891 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0046 | 0.823 | 1 |
Brugia malayi | RE15519p | 0.0046 | 0.823 | 0.823 |
Brugia malayi | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus granulosus | neuropeptide s receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0037 | 0.61 | 0.7413 |
Brugia malayi | Dopamine receptor | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0014 | 0.0891 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | cytochrome P450 | 0.0014 | 0.0891 | 0.0891 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | g protein coupled receptor | 0.0046 | 0.823 | 1 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0046 | 0.823 | 0.823 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0046 | 0.823 | 0.823 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0014 | 0.0891 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.823 | 1 |
Onchocerca volvulus | 0.0046 | 0.823 | 0.5 | |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0014 | 0.0891 | 0.5 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0014 | 0.0891 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | GnHR receptor homolog | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0046 | 0.823 | 1 |
Brugia malayi | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0046 | 0.823 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0046 | 0.823 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0034 | 0.5535 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.823 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.2931 | 0.2931 |
Echinococcus granulosus | orexin receptor type 2 | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0046 | 0.823 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Brugia malayi | hypothetical protein | 0.0046 | 0.823 | 0.823 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 0.42 mM | Inhibition of human recombinant soluble His-tagged beta3-GalT1 expressed in insect cells using GlcNAcbeta-Bn as substrate after 1 hr | ChEMBL. | 23375091 |
Inhibition (binding) | < 1 % | Inhibition of human GNT2 GalNAc-transferase using GnMan3-octyl as substrate at 0.5 mM after 1 hr in presence of phosphatidylcholine | ChEMBL. | 23375091 |
Inhibition (binding) | < 1 % | Inhibition of human GNT1 using Man3-octyl as substrate at 0.5 mM after 1 hr in presence of phosphatidylcholine | ChEMBL. | 23375091 |
Inhibition (binding) | < 1 % | Inhibition of human C1GalT GlcNAc-transferase using GlcNAcalpha-Bn as substrate at 0.5 mM after 1 hr in presence of phosphatidylcholine | ChEMBL. | 23375091 |
Inhibition (binding) | = 40.7 % | Inhibition of bovine milk beta4-GalT1 using GlcNAcbeta-Bn as substrate at 0.5 mM after 1 hr relative to control | ChEMBL. | 23375091 |
Inhibition (binding) | = 40.7 % | Inhibition of human recombinant soluble His-tagged beta4-GalT1 expressed in Escherichia coli BL21 using GlcNAcbeta-Bn as substrate at 0.5 mM after 1 hr relative to control | ChEMBL. | 23375091 |
Inhibition (binding) | = 79.2 % | Inhibition of human recombinant soluble His-tagged beta3-GalT5 expressed in insect cells using GlcNAcbeta-Bn as substrate at 0.5 mM after 1 hr relative to control | ChEMBL. | 23375091 |
Inhibition (binding) | = 80 % | Inhibition of human B3GnT6 using GalNAcalpha-Bn as substrate at 0.5 mM after 1 hr in presence of phosphatidylcholine | ChEMBL. | 23375091 |
Inhibition (binding) | = 100 % | Inhibition of human C2GnT1 using Galbeta3GalNAcalpha-Bn as substrate at 0.5 mM after 1 hr in presence of phosphatidylcholine | ChEMBL. | 23375091 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.