Detailed information for compound 1793113

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 292.413 | Formula: C18H28O3
  • H donors: 2 H acceptors: 3 LogP: 2.05 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CC(C)(C)[C@H](C2=C1[C@]1(O)C[C@@](C2)(C)CC(C1)(C)C)O
  • InChi: 1S/C18H28O3/c1-15(2)8-17(5)6-11-13(18(21,9-15)10-17)12(19)7-16(3,4)14(11)20/h14,20-21H,6-10H2,1-5H3/t14-,17+,18+/m0/s1
  • InChiKey: CUIHZTAQXSGFRY-BMGDILEWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.004 0.0401 0.068
Schistosoma mansoni chromobox protein 0.0137 0.2343 0.2354
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0337 0.0339
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Brugia malayi Animal haem peroxidase family protein 0.004 0.0402 0.125
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0297 0.0298
Echinococcus granulosus protein kinase c iota type 0.0035 0.0297 0.0297
Loa Loa (eye worm) blistered cuticle protein 3 0.004 0.0402 0.0683
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0579 0.0579
Leishmania major cathepsin L-like protease 0.0064 0.0876 0.3809
Onchocerca volvulus Putative organic anion transporter 0.0059 0.0776 0.2307
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0177 0.0343
Schistosoma mansoni hypothetical protein 0.0298 0.5584 0.5611
Trichomonas vaginalis AGC family protein kinase 0.0105 0.1705 0.7226
Loa Loa (eye worm) hypothetical protein 0.0037 0.0337 0.0573
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0035 0.0297 0.0297
Loa Loa (eye worm) CHromoDomain protein family member 0.0022 0.0044 0.0075
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0067 0.0948 0.4313
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0579 0.0579
Brugia malayi Heterochromatin protein 1 0.0137 0.2343 0.7282
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0058 0.0756 0.2955
Chlamydia trachomatis glycogen phosphorylase 0.0109 0.1781 1
Schistosoma mansoni serine/threonine-protein kinase 0.0071 0.1028 0.1032
Entamoeba histolytica glycogen phosphorylase, putative 0.0109 0.1781 1
Onchocerca volvulus Chorion peroxidase homolog 0.004 0.0402 0.1129
Brugia malayi Protein kinase domain containing protein 0.0035 0.0297 0.0923
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.1736 0.8342
Trichomonas vaginalis AGC family protein kinase 0.0039 0.0377 0.1448
Onchocerca volvulus 0.004 0.0402 0.1129
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1752 0.7431
Loa Loa (eye worm) hypothetical protein 0.0059 0.0776 0.1317
Brugia malayi protein kinase C II. 0.0035 0.0297 0.0923
Echinococcus granulosus protein kinase c epsilon type 0.0035 0.0297 0.0297
Leishmania major cathepsin L-like protease 0.0064 0.0876 0.3809
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0035 0.0297 0.0297
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0337 0.0339
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0337 0.1276
Loa Loa (eye worm) hypothetical protein 0.0035 0.0297 0.0504
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0061 0.0812 0.3356
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0177 0.0579
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0579 0.0582
Brugia malayi sodium-independent organic anion transporter family protein 0.0059 0.0776 0.2412
Trypanosoma cruzi histone deacetylase, putative 0.0061 0.0828 0.3468
Echinococcus multilocularis histone deacetylase 7 0.0061 0.0828 0.0828
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0533 0.1382
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0401 0.0919
Echinococcus multilocularis rac serine:threonine kinase 0.0071 0.1028 0.1028
Echinococcus multilocularis histone deacetylase 0.0061 0.0828 0.0828
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0193 0.3477 0.3477
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1752 1
Trypanosoma cruzi Protein kinase B 0.0071 0.1028 0.4877
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0075
Echinococcus granulosus nervana 2 0.0066 0.0922 0.0922
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0756 0.2955
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0177 0.0579
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0177 0.0579
Echinococcus multilocularis serine threonine protein kinase 0.0035 0.0297 0.0297
Brugia malayi Associated with TFs and helicases family protein 0.0022 0.0044 0.0137
Toxoplasma gondii histone deacetylase HDAC1 0.0061 0.0828 0.2019
Echinococcus granulosus peroxidasin 0.004 0.0402 0.0402
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0022 0.0044 0.0044
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0716 0.0716
Loa Loa (eye worm) hypothetical protein 0.0046 0.0525 0.0891
Entamoeba histolytica protein kinase, putative 0.0035 0.0297 0.1457
Echinococcus multilocularis glycogen phosphorylase 0.0109 0.1781 0.1781
Brugia malayi hypothetical protein 0.004 0.0402 0.125
Trypanosoma brucei trypanothione reductase 0.0047 0.0533 0.1382
Schistosoma mansoni hypothetical protein 0.0022 0.0044 0.0044
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0022 0.0044 0.0137
Brugia malayi glutathione reductase 0.0047 0.0533 0.1657
Echinococcus granulosus Solute carrier organic anion transporter family 0.0059 0.0776 0.0776
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0059 0.0776 0.0776
Brugia malayi chromobox protein homolog 3 0.0077 0.1135 0.3528
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0297 0.11
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1752 0.9838
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0297 0.11
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.1135 0.4746
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0297 0.0298
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0401 0.1246
Echinococcus multilocularis follistatin 0.004 0.0401 0.0401
Echinococcus multilocularis glycogen phosphorylase 0.0109 0.1781 0.1781
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0876 0.3809
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0035 0.0297 0.0504
Brugia malayi sodium-independent organic anion transporter family protein 0.0059 0.0776 0.2412
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0337 0.0337
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0716 0.2225
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.006 0.0802 0.1361
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0602 0.187
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0579 0.0579
Schistosoma mansoni peroxidasin 0.004 0.0402 0.0404
Echinococcus granulosus Protein kinase C brain isozyme 0.0035 0.0297 0.0297
Echinococcus granulosus follistatin 0.004 0.0401 0.0401
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0716 0.0719
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.1975 1
Brugia malayi CHD4 protein 0.0022 0.0044 0.0137
Echinococcus multilocularis histone deacetylase 6 0.0061 0.0828 0.0828
Echinococcus granulosus protein kinase C gamma type 0.0035 0.0297 0.0297
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0177 0.1474
Loa Loa (eye worm) agrin synaptic family protein 0.004 0.0401 0.068
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Brugia malayi p70 ribosomal S6 kinase beta 0.0101 0.1625 0.5052
Schistosoma mansoni hypothetical protein 0.0515 0.9952 1
Brugia malayi SPARC precursor 0.004 0.0401 0.1246
Brugia malayi Peroxidasin 0.004 0.0402 0.125
Loa Loa (eye worm) AGC/PKN protein kinase 0.0035 0.0297 0.0504
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0337 0.0999
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0401 0.1246
Loa Loa (eye worm) MBCTL1 0.0056 0.0716 0.1215
Echinococcus multilocularis histone deacetylase 6 0.0061 0.0828 0.0828
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0337 0.1276
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0022 0.0044 0.0044
Onchocerca volvulus 0.006 0.0802 0.2389
Plasmodium vivax histone deacetylase, putative 0.0061 0.0828 0.8676
Toxoplasma gondii protease inhibitor PI2 0.004 0.0401 0.0919
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0071 0.1028 0.4877
Brugia malayi hypothetical protein 0.0059 0.0776 0.2412
Schistosoma mansoni glycogen phosphorylase 0.0109 0.1781 0.1789
Brugia malayi prolyl oligopeptidase family protein 0.018 0.3217 1
Schistosoma mansoni histone deacetylase 4 5 0.0061 0.0828 0.0832
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0058 0.0756 0.1282
Brugia malayi Histone deacetylase family protein 0.0061 0.0828 0.2574
Echinococcus multilocularis peroxidasin 0.004 0.0402 0.0402
Trichomonas vaginalis glycogen phosphorylase, putative 0.0109 0.1781 0.7554
Brugia malayi Protein kinase domain containing protein 0.0035 0.0297 0.0923
Schistosoma mansoni chromobox protein 0.0022 0.0044 0.0044
Onchocerca volvulus Peroxidase homolog 0.004 0.0402 0.1129
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0177 0.1474
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0579 0.0582
Entamoeba histolytica protein kinase, putative 0.0105 0.1705 0.9565
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0022 0.0044 0.0044
Echinococcus granulosus chromobox protein 1 0.0137 0.2343 0.2343
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1752 0.9838
Schistosoma mansoni chromobox protein 0.0137 0.2343 0.2354
Onchocerca volvulus 0.004 0.0402 0.1129
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0058 0.0756 0.2955
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0035 0.0297 0.0297
Schistosoma mansoni glycogen phosphorylase 0.0047 0.0539 0.0542
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0035 0.0297 0.0504
Onchocerca volvulus Peroxidasin homolog 0.004 0.0402 0.1129
Echinococcus multilocularis mitogen activated protein kinase 3 0.0058 0.0756 0.0756
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0297 0.0298
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0402 0.0683
Toxoplasma gondii transporter, major facilitator family protein 0.0059 0.0776 0.1884
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0337 0.1276
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0075
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0067 0.0948 0.0948
Echinococcus granulosus chromobox protein 1 0.0137 0.2343 0.2343
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0177 0.0343
Loa Loa (eye worm) hypothetical protein 0.004 0.0401 0.068
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0075
Echinococcus multilocularis serine:threonine protein kinase 38 0.0035 0.0297 0.0297
Brugia malayi Animal haem peroxidase family protein 0.004 0.0402 0.125
Trypanosoma cruzi MFS transporter, putative 0.0059 0.0776 0.3099
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0066 0.0922 0.0922
Brugia malayi M-phase phosphoprotein, mpp8 0.0022 0.0044 0.0137
Schistosoma mansoni histone deacetylase hda2 0.0061 0.0828 0.0832
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0337 0.169
Trypanosoma brucei rac serine-threonine kinase, putative 0.0105 0.1705 0.9666
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.1736 0.8342
Plasmodium falciparum histone deacetylase, putative 0.0061 0.0828 0.8676
Entamoeba histolytica protein kinase 2, putative 0.0067 0.0948 0.5204
Schistosoma mansoni agrin 0.004 0.0401 0.0403
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.004 0.0401 0.068
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Trichomonas vaginalis AGC family protein kinase 0.0105 0.1705 0.7226
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0579 0.0579
Brugia malayi carbohydrate phosphorylase 0.0109 0.1781 0.5534
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0044 0.0044
Loa Loa (eye worm) phosphofructokinase 0.0107 0.1752 0.2974
Brugia malayi Histone deacetylase family protein 0.0061 0.0828 0.2574
Schistosoma mansoni histone deacetylase 4 5 0.0061 0.0828 0.0832
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0177 0.0579
Loa Loa (eye worm) histone deacetylase 7A 0.0061 0.0828 0.1405
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0061 0.0812 0.0812
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.1975 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Onchocerca volvulus 0.0049 0.0579 0.1687
Brugia malayi Protein cec-1. 0.0022 0.0044 0.0137
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0061 0.0812 0.3356
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Loa Loa (eye worm) hypothetical protein 0.0077 0.1135 0.1926
Loa Loa (eye worm) hypothetical protein 0.0043 0.0457 0.0776
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0177 0.0343
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0716 0.0716
Echinococcus granulosus Chromobox protein 3 0.0022 0.0044 0.0044
Mycobacterium tuberculosis Probable reductase 0.0106 0.1736 0.8342
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0756 0.3095
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0061 0.0812 0.1978
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0533 0.5411
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Trichomonas vaginalis chromobox protein, putative 0.0137 0.2343 1
Echinococcus multilocularis Chromobox protein 3 0.0022 0.0044 0.0044
Onchocerca volvulus 0.0059 0.0776 0.2307
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.018 0.3217 0.3233
Brugia malayi hypothetical protein 0.0022 0.0044 0.0137
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0067 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Loa Loa (eye worm) hypothetical protein 0.0059 0.0776 0.1317
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0047 0.0539 0.0045
Loa Loa (eye worm) glycogen phosphorylase 0.0109 0.1781 0.3021
Trichomonas vaginalis chromobox protein, putative 0.0137 0.2343 1
Trichomonas vaginalis AGC family protein kinase 0.0105 0.1705 0.7226
Brugia malayi MH2 domain containing protein 0.0116 0.1934 0.6011
Entamoeba histolytica PH domain containing protein kinase, putative 0.0071 0.1028 0.5664
Leishmania major histone deacetylase, putative 0.0061 0.0828 0.3468
Loa Loa (eye worm) hypothetical protein 0.004 0.0401 0.068
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.018 0.3217 1
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0297 0.0298
Trichomonas vaginalis chromobox protein, putative 0.0082 0.1252 0.5254
Echinococcus multilocularis Chromo domain 0.0022 0.0044 0.0044
Echinococcus multilocularis expressed protein 0.004 0.0401 0.0401
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0177 0.1474
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0876 0.3809
Echinococcus multilocularis neuropeptide receptor A26 0.0517 1 1
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0716 0.0716
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0297 0.11
Echinococcus granulosus agrin 0.004 0.0401 0.0401
Brugia malayi Hr1 repeat family protein 0.0035 0.0297 0.0923
Echinococcus granulosus geminin 0.0515 0.9952 0.9952
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Loa Loa (eye worm) prolyl oligopeptidase 0.018 0.3217 0.5459
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1752 0.1761
Echinococcus granulosus nervana 2 0.0066 0.0922 0.0922
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0035 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0059 0.0776 0.1317
Entamoeba histolytica PH domain containing protein kinase, putative 0.0071 0.1028 0.5664
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0533 0.0904
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0716 0.0716
Plasmodium falciparum histone deacetylase 2 0.0061 0.0828 0.8676
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.1736 0.8342
Echinococcus granulosus glycogen phosphorylase 0.0109 0.1781 0.1781
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0177 0.0579
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.1752 0.1752
Echinococcus granulosus histone deacetylase 0.0061 0.0828 0.0828
Brugia malayi mbt repeat family protein 0.0049 0.0579 0.1801
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0402 0.0683
Trichomonas vaginalis AGC family protein kinase 0.0105 0.1705 0.7226
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0756 0.3095
Loa Loa (eye worm) hypothetical protein 0.0059 0.0776 0.1317
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0101 0.1625 0.2758
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.1975 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.1975 1
Toxoplasma gondii thioredoxin reductase 0.0047 0.0533 0.1259
Echinococcus multilocularis expressed protein 0.0368 0.7006 0.7006
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0177 0.1474
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0579 0.0983
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0035 0.0297 0.0504
Echinococcus granulosus histone deacetylase 7 0.0061 0.0828 0.0828
Brugia malayi Protein kinase domain containing protein 0.0105 0.1705 0.53
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.0215 0.3929 1
Brugia malayi hypothetical protein 0.0059 0.0776 0.2412
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.1736 0.8342
Loa Loa (eye worm) STAT protein 0.0152 0.2663 0.4518
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0539 0.2853
Brugia malayi Valyl-tRNA synthetase 0.0022 0.0044 0.0137
Trypanosoma cruzi histone deacetylase, putative 0.0061 0.0828 0.3468
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0685 0.2789
Entamoeba histolytica glycogen phosphorylase, putative 0.0109 0.1781 1
Echinococcus granulosus serine:threonine protein kinase N2 0.0035 0.0297 0.0297
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0077 0.1135 0.3438
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0044 0.0044
Plasmodium vivax glutathione reductase, putative 0.0047 0.0533 0.5411
Echinococcus multilocularis nervana 2 0.0066 0.0922 0.0922
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0337 0.0337
Brugia malayi hypothetical protein 0.0046 0.0525 0.1632
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0177 0.0767
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1752 0.7431
Onchocerca volvulus Putative organic anion transporter 0.0059 0.0776 0.2307
Onchocerca volvulus 0.0059 0.0776 0.2307
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.1752 0.0695
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0756 0.3095
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.1135 0.4746
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0401 0.0919
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0337 0.0337
Trypanosoma cruzi histone deacetylase, putative 0.0061 0.0828 0.3468
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0401 0.0919
Trypanosoma brucei protein kinase, putative 0.0058 0.0756 0.2955
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.1752 0.8458
Schistosoma mansoni serine/threonine kinase 0.0035 0.0297 0.0298
Brugia malayi 6-phosphofructokinase 0.0107 0.1752 0.5447
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0756 0.0759
Echinococcus granulosus glycogen phosphorylase 0.0109 0.1781 0.1781
Brugia malayi SET domain containing protein 0.0022 0.0044 0.0137
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0337 0.0337
Echinococcus granulosus Dipeptidyl peptidase 9 0.0061 0.0812 0.0812
Giardia lamblia Kinase, CMGC MAPK 0.0058 0.0756 0.3607
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0337 0.0337
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Loa Loa (eye worm) hypothetical protein 0.0056 0.0716 0.1215
Brugia malayi 6-phosphofructokinase 0.0107 0.1752 0.5447
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Onchocerca volvulus 0.0059 0.0776 0.2307
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.018 0.3217 0.3217
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0061 0.0812 0.3356
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0034 0.0272 0.099
Brugia malayi MAP kinase sur-1 0.0058 0.0756 0.2349
Echinococcus granulosus Glycosyl transferase family 35 0.0109 0.1781 0.1781
Echinococcus multilocularis agrin 0.004 0.0401 0.0401
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0075
Plasmodium falciparum thioredoxin reductase 0.0047 0.0533 0.5411
Onchocerca volvulus Peroxidase homolog 0.004 0.0402 0.1129
Schistosoma mansoni hypothetical protein 0.0515 0.9952 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0075
Echinococcus multilocularis chromobox protein 2 0.0022 0.0044 0.0044
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0035 0.0297 0.0297
Trichomonas vaginalis chromobox protein, putative 0.0082 0.1252 0.5254
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.1752 1
Echinococcus multilocularis chromobox protein 1 0.0137 0.2343 0.2343
Leishmania major cathepsin L-like protease 0.0064 0.0876 0.3809
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0035 0.0297 0.0504
Onchocerca volvulus Putative organic anion transporter 0.0059 0.0776 0.2307
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0044 0.0044
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0401 0.1246
Trichomonas vaginalis AGC family protein kinase 0.0105 0.1705 0.7226
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0066 0.0922 0.0922
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1752 0.1761
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0058 0.0756 0.1832
Echinococcus multilocularis geminin 0.0515 0.9952 0.9952
Plasmodium vivax histone deacetylase 2, putative 0.0061 0.0828 0.8676
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0058 0.0756 0.2955
Onchocerca volvulus Dual oxidase homolog 0.004 0.0402 0.1129
Schistosoma mansoni serine/threonine-protein kinase 0.0071 0.1028 0.1032
Loa Loa (eye worm) hypothetical protein 0.0043 0.0457 0.0776
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.1752 1
Schistosoma mansoni atypical protein kinase C 0.0035 0.0297 0.0298
Echinococcus granulosus mitogen activated protein kinase 3 0.0058 0.0756 0.0756
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Brugia malayi STAT protein, DNA binding domain containing protein 0.0152 0.2663 0.8276
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0402 0.0683
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0058 0.0756 0.2955
Brugia malayi phosphofructokinase 0.0107 0.1752 0.5447
Onchocerca volvulus 0.0059 0.0776 0.2307
Loa Loa (eye worm) hypothetical protein 0.0313 0.5894 1
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0061 0.0812 0.3356
Schistosoma mansoni follistatin 0.004 0.0401 0.0403
Leishmania major histone deacetylase, putative 0.0061 0.0828 0.3468
Echinococcus granulosus histone deacetylase 6 0.0061 0.0828 0.0828
Echinococcus granulosus mitogen activated protein kinase 0.0058 0.0756 0.0756
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0337 0.1049
Brugia malayi Animal haem peroxidase family protein 0.004 0.0402 0.125
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0297 0.0298
Entamoeba histolytica protein kinase, putative 0.0105 0.1705 0.9565
Echinococcus granulosus expressed protein 0.0368 0.7006 0.7006
Echinococcus multilocularis nervana 2 0.0066 0.0922 0.0922
Loa Loa (eye worm) histone deacetylase 0.0061 0.0828 0.1405
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0539 0.2853
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.004 0.0401 0.1246
Brugia malayi Animal haem peroxidase family protein 0.004 0.0402 0.125
Loa Loa (eye worm) AGC/AKT protein kinase 0.0105 0.1705 0.2893
Brugia malayi secreted modular calcium-binding protein 1 0.004 0.0401 0.1246
Trypanosoma brucei histone deacetylase, putative 0.0061 0.0828 0.3468
Echinococcus multilocularis histone deacetylase 6 0.0061 0.0828 0.0828
Loa Loa (eye worm) hypothetical protein 0.0059 0.0776 0.1317
Schistosoma mansoni organic anion transporter 0.0059 0.0776 0.078
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0075
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0579 0.0582
Echinococcus multilocularis protein kinase c iota type 0.0035 0.0297 0.0297
Brugia malayi sodium-independent organic anion transporter family protein 0.0059 0.0776 0.2412
Loa Loa (eye worm) hypothetical protein 0.0049 0.0579 0.0983
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0337 0.0337
Echinococcus multilocularis Glycosyl transferase, family 35 0.0109 0.1781 0.1781
Echinococcus granulosus serine/threonine protein kinase 0.0071 0.1028 0.1028
Echinococcus granulosus NDR protein kinase 0.0035 0.0297 0.0297
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0059 0.0776 0.1317
Trypanosoma brucei histone deacetylase 4 0.0061 0.0828 0.3468
Entamoeba histolytica glycogenphosphorylase, putative 0.0047 0.0539 0.2853
Echinococcus multilocularis Glutaredoxin protein 5 0.0066 0.0922 0.0922
Giardia lamblia Kinase, AGC PKA 0.0067 0.0948 0.4806
Onchocerca volvulus Glycogen phosphorylase homolog 0.0109 0.1781 0.5472
Brugia malayi hypothetical protein 0.012 0.2011 0.6251
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0193 0.3477 0.3477
Echinococcus granulosus Chromo domain 0.0022 0.0044 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1752 0.7431
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0022 0.0044 0.0044
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0082 0.1252 0.3807
Entamoeba histolytica protein kinase, putative 0.0101 0.1625 0.9106
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0765 0.3023
Loa Loa (eye worm) hypothetical protein 0.004 0.0402 0.0683
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0756 0.3095
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1752 1
Loa Loa (eye worm) helicase 0.0022 0.0044 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0297 0.0298
Leishmania major trypanothione reductase 0.0047 0.0533 0.1382
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0067 0.0948 1
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0067 0.0948 1
Echinococcus multilocularis protein kinase c epsilon type 0.0035 0.0297 0.0297
Onchocerca volvulus Peroxidasin homolog 0.004 0.0402 0.1129
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0059 0.0776 0.0776
Loa Loa (eye worm) hypothetical protein 0.004 0.0401 0.068
Onchocerca volvulus 0.0059 0.0776 0.2307
Brugia malayi mbt repeat family protein 0.0049 0.0579 0.1801
Echinococcus granulosus chromobox protein 2 0.0022 0.0044 0.0044
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0533 0.0533
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0402 0.0683
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0061 0.0812 0.0816
Loa Loa (eye worm) heterochromatin protein 1 0.0137 0.2343 0.3976
Schistosoma mansoni peroxidasin 0.004 0.0402 0.0404
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1752 0.7431
Echinococcus multilocularis mitogen activated protein kinase 0.0058 0.0756 0.0756
Brugia malayi Blistered cuticle protein 3 0.004 0.0402 0.125
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1934 0.3281
Schistosoma mansoni glycogen phosphorylase 0.0109 0.1781 0.1789
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1934 0.3281
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0061 0.0812 0.3356
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0579 0.1687
Trichomonas vaginalis AGC family protein kinase 0.0105 0.1705 0.7226
Brugia malayi prostaglandin transporter 0.0059 0.0776 0.2412
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1752 0.2974
Plasmodium falciparum glutathione reductase 0.0047 0.0533 0.5411
Schistosoma mansoni organic anion transporter 0.0059 0.0776 0.078
Toxoplasma gondii AGC kinase 0.0101 0.1625 0.4071
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1752 0.2974
Trichomonas vaginalis glycogen phosphorylase, putative 0.0109 0.1781 0.7554
Trichomonas vaginalis AGC family protein kinase 0.0105 0.1705 0.7226
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1752 0.9838
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0876 0.3809
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0876 0.3809
Trypanosoma brucei histone deacetylase 3 0.0061 0.0828 0.3468
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.018 0.3217 0.3217
Schistosoma mansoni chromobox protein 0.0022 0.0044 0.0044
Echinococcus granulosus serine threonine protein kinase nrc 0.0067 0.0948 0.0948
Loa Loa (eye worm) AGC/NDR protein kinase 0.0035 0.0297 0.0504
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.004 0.0401 0.0919
Echinococcus multilocularis chromobox protein 1 0.0137 0.2343 0.2343
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0059 0.0776 0.0776
Brugia malayi Animal haem peroxidase family protein 0.004 0.0402 0.125
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.1752 1
Giardia lamblia Glycogen phosphorylase 0.0109 0.1781 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0177 0.0579
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0297 0.0298
Loa Loa (eye worm) hypothetical protein 0.0059 0.0776 0.1317
Loa Loa (eye worm) hypothetical protein 0.0059 0.0776 0.1317
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.1752 0.1752
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.1736 0.8342
Echinococcus granulosus neuropeptide receptor A26 0.0517 1 1
Brugia malayi Thioredoxin reductase 0.0047 0.0533 0.1657
Echinococcus multilocularis neuropeptide s receptor 0.0517 1 1
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0035 0.0297 0.0297
Onchocerca volvulus 0.004 0.0402 0.1129
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0756 0.2955
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0177 0.0579
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0075
Echinococcus granulosus histone deacetylase 6 0.0061 0.0828 0.0828
Brugia malayi prolyl oligopeptidase family protein 0.0061 0.0812 0.2525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Echinococcus granulosus Glutaredoxin protein 5 0.0066 0.0922 0.0922
Echinococcus multilocularis serine:threonine protein kinase N2 0.0035 0.0297 0.0297
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0533 0.0533
Echinococcus multilocularis serine:threonine protein kinase N2 0.0035 0.0297 0.0297
Loa Loa (eye worm) glutathione reductase 0.0047 0.0533 0.0904
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0058 0.0756 0.2955
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Echinococcus granulosus histone deacetylase 6 0.0061 0.0828 0.0828
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0035 0.0297 0.0297
Onchocerca volvulus 0.004 0.0401 0.1125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0876 0.3809
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0022 0.0044 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0685 0.2789

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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