Detailed information for compound 1802583

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 620.686 | Formula: C35H40O10
  • H donors: 1 H acceptors: 6 LogP: 3.85 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)O[C@@H]1[C@H]2C[C@@H]([C@]3([C@@]1(OC2(C)C)[C@@](C)(O)[C@H]([C@H]([C@@H]3OC(=O)c1ccccc1)C(=O)C)C(=O)C)C)OC(=O)c1ccccc1
  • InChi: 1S/C35H40O10/c1-19(36)26-27(20(2)37)34(7,41)35-28(42-21(3)38)24(32(4,5)45-35)18-25(43-30(39)22-14-10-8-11-15-22)33(35,6)29(26)44-31(40)23-16-12-9-13-17-23/h8-17,24-29,41H,18H2,1-7H3/t24-,25+,26-,27+,28-,29+,33-,34+,35-/m1/s1
  • InChiKey: CDRGBGYYKCRJAA-ADTUCRFWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0038 0.044
Leishmania major hypothetical protein, conserved 0.0015 0.008 0.0218
Schistosoma mansoni nuclear hormone receptor 0.001 0.0038 0.0101
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0573 0.2056
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0816 0.2964
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0038 0.0096
Echinococcus granulosus lysine specific demethylase 5A 0.0057 0.0419 0.1114
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0021 0.0131 0.0351
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0955
Echinococcus multilocularis transcription factor Dp 1 0.0044 0.0315 0.042
Echinococcus multilocularis ATP binding cassette sub family G 0.0021 0.0131 0.0173
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0028 0.0035
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0038 0.0048
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0038 0.0048
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0038 0.0049
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0071 0.0524 0.1873
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0071 0.0524 1
Brugia malayi cytochrome P450 0.0007 0.0021 0.0026
Schistosoma mansoni hypothetical protein 0.004 0.0277 0.074
Onchocerca volvulus 0.0033 0.0228 0.019
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0002 0.0005
Echinococcus granulosus ATP binding cassette sub family G 0.0021 0.0131 0.0346
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0038 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0038 0.0049
Brugia malayi jmjC domain containing protein 0.0015 0.008 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0816 0.2179
Schistosoma mansoni cpg binding protein 0.0035 0.0243 0.0648
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0021 0.0131 0.2193
Echinococcus multilocularis 0.0007 0.0021 0.0026
Plasmodium falciparum telomerase reverse transcriptase 0.0344 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0038 0.044
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0071 0.0524 0.1393
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0816 0.2964
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0816 1
Echinococcus granulosus cytochrome P450 2K1 0.0007 0.0021 0.0051
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.008 0.0218
Schistosoma mansoni jumonji/arid domain-containing protein 0.0057 0.0419 0.1119
Mycobacterium leprae putative cytochrome p450 0.0007 0.0021 0.5
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0108 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0038 0.0049
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0038 0.0101
Giardia lamblia Telomerase catalytic subunit 0.0344 0.2704 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0038 0.0096
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.008 0.0218
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0423 0.5172
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0095 0.0124
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.008 0.0208
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.008 0.0104
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0344 0.2704 1
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0021 0.0131 0.0411
Schistosoma mansoni hypothetical protein 0.0475 0.3747 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0021 0.0131 0.2193
Schistosoma mansoni cytochrome P450 0.0007 0.0021 0.0057
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0038 0.0101
Schistosoma mansoni coup transcription factor 0.001 0.0038 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0038 0.044
Toxoplasma gondii RNA-directed DNA polymerase 0.0344 0.2704 1
Loa Loa (eye worm) histone methyltransferase 0.001 0.0044 0.0517
Loa Loa (eye worm) hypothetical protein 0.0058 0.0423 0.5172
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0028 0.0074
Schistosoma mansoni protein phosphatase 2C 0.0015 0.008 0.0213
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0021 0.0131 0.0411
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0526 0.1403
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.0002 0.0005
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.008 0.0213
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0077 0.0573 0.7008
Echinococcus multilocularis mitogen activated protein kinase 0.0107 0.0816 0.1091
Mycobacterium leprae Conserved hypothetical protein 0.0007 0.0021 0.5
Brugia malayi ABC transporter family protein 0.0018 0.0106 0.0143
Schistosoma mansoni hypothetical protein 0.0018 0.0104 0.0277
Plasmodium vivax telomerase reverse transcriptase, putative 0.0344 0.2704 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0168 0.204
Brugia malayi nuclear receptor NHR-88 0.001 0.0038 0.0049
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0038 0.0049
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.008 0.0218
Brugia malayi jmjC domain containing protein 0.0057 0.0419 0.0575
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0108 0.0283
Brugia malayi MAP kinase sur-1 0.0107 0.0816 0.1122
Schistosoma mansoni phd/f-box containing protein 0.0015 0.008 0.0213
Echinococcus granulosus mitogen activated protein kinase 3 0.0107 0.0816 0.2175
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.008 0.0955
Leishmania major telomerase reverse transcriptase, putative 0.0344 0.2704 1
Brugia malayi jmjC domain containing protein 0.0015 0.008 0.0107
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0077 0.0573 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0077 0.0573 0.1529
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0021 0.0131 0.2193
Echinococcus multilocularis lysine specific demethylase 5A 0.0056 0.0404 0.0539
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0038 0.044
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0038 0.044
Trypanosoma brucei ABC transporter, putative 0.0021 0.0131 0.0411
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0423 0.058
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0038 0.0049
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0038 0.0101
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0071 0.0524 0.0699
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0168 0.2924
Brugia malayi CXXC zinc finger family protein 0.0033 0.0228 0.0311
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.008 0.0213
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0108 0.1299
Toxoplasma gondii aldehyde dehydrogenase 0.0071 0.0524 0.1873
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.008 0.0218
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0043 0.0057
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0038 0.0101
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0038 0.0049
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0038 0.0048
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0107 0.0816 0.2964
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0038 0.0096
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0228 0.277
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0168 0.204
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0344 0.2704 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0038 0.0048
Schistosoma mansoni thyroid hormone receptor 0.001 0.0038 0.0101
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0028 0.0069
Loa Loa (eye worm) hypothetical protein 0.001 0.0038 0.044
Loa Loa (eye worm) hypothetical protein 0.001 0.0038 0.044
Trypanosoma brucei ATP-binding cassette protein, putative 0.0021 0.0131 0.0411
Schistosoma mansoni jumonji domain containing protein 0.0056 0.0404 0.1078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0038 0.044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0038 0.044
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0108 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0038 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0038 0.0096
Loa Loa (eye worm) hypothetical protein 0.004 0.0277 0.3379
Loa Loa (eye worm) hypothetical protein 0.0018 0.0108 0.1299
Schistosoma mansoni cpg binding protein 0.0035 0.0243 0.0648
Trypanosoma brucei telomerase reverse transcriptase 0.0344 0.2704 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0095 0.0248
Echinococcus granulosus ATP binding cassette sub family G 0.0021 0.0131 0.0346
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0955
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0288
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0038 0.044
Schistosoma mansoni jumonji/arid domain-containing protein 0.0057 0.0419 0.1119
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0038 0.0048
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0524 0.1398
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0168 0.0548
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0816 1
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0108 0.0146
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.008 0.0208
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0038 0.0049
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.008 0.0955
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0168 0.0548
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.008 0.0104
Leishmania major cytochrome p450-like protein 0.0026 0.0168 0.0548
Loa Loa (eye worm) hypothetical protein 0.001 0.0038 0.044
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0465 0.1656
Echinococcus granulosus ATP binding cassette sub family G 0.0021 0.0131 0.0346
Schistosoma mansoni cpg binding protein 0.0033 0.0228 0.0608
Brugia malayi jmjC domain containing protein 0.0015 0.008 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0038 0.0049
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0077 0.0573 0.1524
Brugia malayi steroid hormone receptor 0.001 0.0038 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0816 1
Brugia malayi jmjC domain containing protein 0.0015 0.008 0.0107
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0038 0.0101
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0038 0.0101
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0288
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0038 0.0049
Giardia lamblia Kinase, CMGC MAPK 0.0107 0.0816 0.2668
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0028 0.0035
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0038 0.0096
Brugia malayi Telomerase reverse transcriptase 0.0916 0.7258 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0107 0.0816 0.2964
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.008 0.0955
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0038 0.0049
Brugia malayi Cytochrome P450 family protein 0.0026 0.0168 0.0229
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0942 0.7465 1
Echinococcus multilocularis cpg binding protein 0.0035 0.0243 0.0323
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0038 0.0049
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0044 0.0112
Echinococcus multilocularis dnaJ subfamily B 0.0475 0.3747 0.5017
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.008 0.0104
Echinococcus granulosus phd:f box containing protein 0.0015 0.008 0.0208
Echinococcus granulosus dnaJ subfamily B 0.0475 0.3747 1
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0038 0.0101
Echinococcus multilocularis phd:f box containing protein 0.0015 0.008 0.0104
Echinococcus multilocularis ATP binding cassette sub family G 0.0021 0.0131 0.0173
Schistosoma mansoni hypothetical protein 0.0007 0.0021 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0816 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0038 0.0048
Loa Loa (eye worm) hypothetical protein 0.0018 0.0109 0.1311
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0108 0.0142
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0077 0.0573 0.0786
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0021 0.0131 0.0411
Trypanosoma brucei protein kinase, putative 0.0107 0.0816 0.2964
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0524 0.1398
Loa Loa (eye worm) hypothetical protein 0.0015 0.008 0.0955
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0107 0.0816 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0038 0.0048
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0524 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0038 0.0096
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0108 0.0146
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0038 0.0096
Loa Loa (eye worm) hypothetical protein 0.001 0.0038 0.044
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0038 0.0049
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.008 0.0218
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0038 0.0101
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0044 0.0056
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0168 0.204
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.008 0.0208
Brugia malayi Cytochrome P450 family protein 0.0007 0.0021 0.0026
Brugia malayi jmjC domain containing protein 0.0056 0.0404 0.0554
Echinococcus multilocularis ATP binding cassette sub family G 0.0021 0.0131 0.0173
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0107 0.0816 0.2964
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0056 0.0404 0.0539
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0107 0.0816 0.2964
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0168 0.0548
Echinococcus granulosus mitogen activated protein kinase 0.0107 0.0816 0.2175
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0524 1
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0018 0.0104 0.164
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0288
Loa Loa (eye worm) hypothetical protein 0.001 0.0038 0.044
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0038 0.0048
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0077 0.0573 0.2056
Echinococcus granulosus GPCR family 2 0.0018 0.0108 0.0283
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0423 0.058
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.001 0.0038 0.044
Echinococcus granulosus FTZ F1 alpha 0.001 0.0038 0.0096
Echinococcus multilocularis mitogen activated protein kinase 3 0.0107 0.0816 0.1091
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0288
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0056 0.0404 0.1073
Loa Loa (eye worm) cytochrome P450 0.0007 0.0021 0.0236
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0038 0.0048
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0107 0.0816 0.2964
Schistosoma mansoni thyroid hormone receptor 0.001 0.0038 0.0101
Brugia malayi nuclear hormone receptor 0.001 0.0038 0.0049
Brugia malayi ecdysteroid receptor 0.001 0.0038 0.0049
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0028 0.0069
Loa Loa (eye worm) ABC transporter 0.0018 0.0106 0.1272
Echinococcus multilocularis GPCR, family 2 0.0018 0.0108 0.0142
Echinococcus granulosus cpg binding protein 0.0035 0.0243 0.0643
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0038 0.044
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.0021 0.0236
Trypanosoma cruzi ABC transporter, putative 0.0021 0.0131 0.0411
Brugia malayi Cytochrome P450 family protein 0.0007 0.0021 0.0026
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0107 0.0816 0.2964
Plasmodium vivax ABC transporter G family member 2, putative 0.0021 0.0131 0.0197
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0573 0.2056
Plasmodium falciparum ABC transporter G family member 2 0.0021 0.0131 0.0197
Echinococcus granulosus transcription factor Dp 1 0.0044 0.0315 0.0837
Schistosoma mansoni jumonji domain containing protein 0.0015 0.008 0.0213
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0277 0.0379
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0021 0.0131 0.0411
Schistosoma mansoni ABC transporter 0.0018 0.0106 0.0282
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.001 0.0038 0.044
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.0419 0.5122
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0038 0.0096
Brugia malayi Cytochrome P450 family protein 0.0026 0.0168 0.0229
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0573 0.2056
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0038 0.0101
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0524 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0077 0.0573 0.0765

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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