Detailed information for compound 1802838

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 404.915 | Formula: C22H17ClN4S
  • H donors: 0 H acceptors: 0 LogP: 5.83 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: C/N=C(\c1ccccc1)/N=c/1\snc(n1c1ccc(cc1)Cl)c1ccccc1
  • InChi: 1S/C22H17ClN4S/c1-24-20(16-8-4-2-5-9-16)25-22-27(19-14-12-18(23)13-15-19)21(26-28-22)17-10-6-3-7-11-17/h2-15H,1H3/b24-20+,25-22-
  • InChiKey: FKFYVSISXYWMCG-SXTKCNFBSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0028 0.0074
Giardia lamblia Kinase, CMGC MAPK 0.0103 0.0816 0.2668
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0288
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0009 0.0038 0.0049
Schistosoma mansoni RAR-like nuclear receptor 0.0009 0.0038 0.0101
Echinococcus multilocularis thyroid hormone receptor alpha 0.0009 0.0038 0.0048
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0009 0.0038 0.0096
Loa Loa (eye worm) hypothetical protein 0.0009 0.0038 0.044
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0168 0.0548
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0009 0.0038 0.0101
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0905 0.7465 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0014 0.008 0.0218
Echinococcus multilocularis cpg binding protein 0.0034 0.0243 0.0323
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0103 0.0816 0.2964
Brugia malayi Telomerase reverse transcriptase 0.088 0.7258 1
Echinococcus granulosus ecdysone induced protein 78C 0.0009 0.0038 0.0096
Echinococcus granulosus phd:f box containing protein 0.0014 0.008 0.0208
Echinococcus granulosus dnaJ subfamily B 0.0457 0.3747 1
Echinococcus multilocularis jumonji domain containing 1A 0.0014 0.008 0.0104
Echinococcus multilocularis dnaJ subfamily B 0.0457 0.3747 0.5017
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.0573 0.0786
Loa Loa (eye worm) ABC transporter 0.0017 0.0106 0.1272
Trypanosoma brucei protein kinase, putative 0.0103 0.0816 0.2964
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0524 0.1398
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.002 0.0131 0.0411
Loa Loa (eye worm) jmjC domain-containing protein 0.0014 0.008 0.0955
Loa Loa (eye worm) hypothetical protein 0.0018 0.0108 0.1299
Echinococcus multilocularis FTZ F1 alpha 0.0009 0.0038 0.0048
Plasmodium vivax ABC transporter G family member 2, putative 0.002 0.0131 0.0197
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.0021 0.0236
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0816 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0014 0.008 0.0955
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0044 0.0056
Brugia malayi Cytochrome P450 family protein 0.0025 0.0168 0.0229
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0524 0.1398
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0009 0.0038 0.0048
Schistosoma mansoni jumonji/arid domain-containing protein 0.0055 0.0419 0.1119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0009 0.0038 0.044
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0108 0.0283
Loa Loa (eye worm) hypothetical protein 0.0014 0.008 0.0955
Echinococcus multilocularis JmjC domain containing protein 4 0.0014 0.008 0.0104
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0168 0.0548
Schistosoma mansoni phd/f-box containing protein 0.0014 0.008 0.0213
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0009 0.0038 0.0048
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0816 1
Echinococcus multilocularis GPCR, family 2 0.0018 0.0108 0.0142
Schistosoma mansoni cpg binding protein 0.0032 0.0228 0.0608
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0465 0.1656
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0131 0.0346
Leishmania major cytochrome p450-like protein 0.0025 0.0168 0.0548
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0038 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0816 1
Schistosoma mansoni phosphatidylserine receptor 0.0014 0.008 0.0213
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0043 0.0057
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0009 0.0038 0.044
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.0573 0.1524
Schistosoma mansoni jumonji domain containing protein 0.0014 0.008 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0009 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.0009 0.0038 0.044
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0103 0.0816 0.2964
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0009 0.0038 0.0049
Echinococcus multilocularis mitogen activated protein kinase 3 0.0103 0.0816 0.1091
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0053 0.0404 0.1073
Brugia malayi cytochrome P450 0.0007 0.0021 0.0026
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0108 0.0142
Trypanosoma cruzi ABC transporter, putative 0.002 0.0131 0.0411
Mycobacterium leprae Conserved hypothetical protein 0.0007 0.0021 0.5
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0103 0.0816 0.2964
Echinococcus granulosus cpg binding protein 0.0034 0.0243 0.0643
Loa Loa (eye worm) hypothetical protein 0.0009 0.0038 0.044
Echinococcus multilocularis 0.0007 0.0021 0.0026
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0288
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0288
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0038 0.0096
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0028 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0038 0.0049
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0038 0.0049
Loa Loa (eye worm) jmjC domain-containing protein 0.0055 0.0419 0.5122
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0277 0.0379
Trypanosoma brucei ABC transporter, putative 0.002 0.0131 0.0411
Schistosoma mansoni hypothetical protein 0.0017 0.0104 0.0277
Echinococcus granulosus jumonji domain containing 1A 0.0014 0.008 0.0208
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.002 0.0131 0.0411
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0315 0.0837
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0131 0.2193
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0573 0.2056
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.0573 0.0765
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0573 0.2056
Schistosoma mansoni steroid hormone receptor ad4bp 0.0009 0.0038 0.0101
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0524 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0038 0.0049
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0168 0.204
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0009 0.0038 0.044
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0009 0.0038 0.0096
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0108 0.0146
Brugia malayi nuclear hormone receptor 0.0009 0.0038 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0009 0.0038 0.0049
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0103 0.0816 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0524 1
Schistosoma mansoni hypothetical protein 0.0007 0.0021 0.0057
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0014 0.008 0.0213
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0168 0.2924
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0009 0.0038 0.0101
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0009 0.0038 0.0101
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0014 0.008 0.0218
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0038 0.0048
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0524 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0103 0.0816 0.2964
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0168 0.204
Echinococcus granulosus mitogen activated protein kinase 0.0103 0.0816 0.2175
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0131 0.0173
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0103 0.0816 0.2964
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0053 0.0404 0.0539
Brugia malayi jmjC domain containing protein 0.0053 0.0404 0.0554
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0009 0.0038 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0009 0.0038 0.044
Brugia malayi ecdysteroid receptor 0.0009 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0109 0.1311
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.0573 0.2056
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0423 0.058
Brugia malayi nuclear receptor NHR-88 0.0009 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.0009 0.0038 0.044
Schistosoma mansoni hypothetical protein 0.0018 0.0108 0.0288
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0017 0.0104 0.164
Echinococcus granulosus FTZ F1 alpha 0.0009 0.0038 0.0096
Echinococcus granulosus GPCR family 2 0.0018 0.0108 0.0283
Echinococcus granulosus cytochrome P450 2K1 0.0007 0.0021 0.0051
Loa Loa (eye worm) hypothetical protein 0.0014 0.008 0.0955
Brugia malayi Cytochrome P450 family protein 0.0007 0.0021 0.0026
Schistosoma mansoni jumonji/arid domain-containing protein 0.0055 0.0419 0.1119
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0816 0.2964
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0816 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0423 0.5172
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0.0095 0.0248
Brugia malayi jmjC domain containing protein 0.0014 0.008 0.0107
Schistosoma mansoni coup transcription factor 0.0009 0.0038 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0009 0.0038 0.0049
Giardia lamblia Telomerase catalytic subunit 0.0331 0.2704 1
Schistosoma mansoni hypothetical protein 0.0457 0.3747 1
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0331 0.2704 1
Leishmania major hypothetical protein, conserved 0.0014 0.008 0.0218
Trypanosoma cruzi ATP-binding cassette protein, putative 0.002 0.0131 0.0411
Brugia malayi jmjC domain containing protein 0.0014 0.008 0.0107
Echinococcus granulosus lysine specific demethylase 6a 0.0014 0.008 0.0208
Loa Loa (eye worm) hypothetical protein 0.0056 0.0423 0.5172
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0028 0.0069
Schistosoma mansoni retinoic acid receptor RXR 0.0009 0.0038 0.0101
Toxoplasma gondii RNA-directed DNA polymerase 0.0331 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0038 0.044
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0131 0.0346
Brugia malayi Steroid receptor seven-up type 2 0.0009 0.0038 0.0049
Schistosoma mansoni cytochrome P450 0.0007 0.0021 0.0057
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0009 0.0038 0.0101
Brugia malayi jmjC domain containing protein 0.0014 0.008 0.0107
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0315 0.042
Trypanosoma brucei ATP-binding cassette protein, putative 0.002 0.0131 0.0411
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0028 0.0035
Brugia malayi Nuclear hormone receptor-like 1 0.0009 0.0038 0.0049
Echinococcus granulosus lysine specific demethylase 5A 0.0055 0.0419 0.1114
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0131 0.0173
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0816 0.2964
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0009 0.0038 0.044
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0038 0.0049
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0573 0.2056
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0038 0.0048
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0014 0.008 0.0218
Onchocerca volvulus 0.0032 0.0228 0.019
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0002 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.0524 1
Brugia malayi Cytochrome P450 family protein 0.0007 0.0021 0.0026
Schistosoma mansoni hypothetical protein 0.0038 0.0277 0.074
Echinococcus multilocularis ecdysone induced protein 78C 0.0009 0.0038 0.0048
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0044 0.0112
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.0524 0.1873
Echinococcus multilocularis phd:f box containing protein 0.0014 0.008 0.0104
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0816 0.2179
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0009 0.0038 0.0049
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0009 0.0038 0.0096
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0131 0.2193
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.0524 0.1393
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0009 0.0038 0.0096
Loa Loa (eye worm) cytochrome P450 0.0007 0.0021 0.0236
Plasmodium falciparum telomerase reverse transcriptase 0.0331 0.2704 1
Plasmodium falciparum ABC transporter G family member 2 0.002 0.0131 0.0197
Schistosoma mansoni cpg binding protein 0.0034 0.0243 0.0648
Brugia malayi steroid hormone receptor 0.0009 0.0038 0.0049
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0009 0.0038 0.0101
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0014 0.008 0.0218
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.0524 0.1873
Schistosoma mansoni protein phosphatase 2C 0.0014 0.008 0.0213
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0108 0.0146
Loa Loa (eye worm) histone methyltransferase 0.001 0.0044 0.0517
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0331 0.2704 1
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0168 0.0548
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0009 0.0038 0.0048
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0103 0.0816 0.2964
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0038 0.0049
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0228 0.277
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0038 0.0049
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0038 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0009 0.0038 0.044
Schistosoma mansoni jumonji domain containing protein 0.0053 0.0404 0.1078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0009 0.0038 0.044
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0009 0.0038 0.0101
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0131 0.0346
Loa Loa (eye worm) hypothetical protein 0.0009 0.0038 0.044
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0028 0.0069
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0131 0.2193
Echinococcus multilocularis lysine specific demethylase 6a 0.0014 0.008 0.0104
Trypanosoma brucei telomerase reverse transcriptase 0.0331 0.2704 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0.0095 0.0124
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0108 0.1299
Schistosoma mansoni cpg binding protein 0.0034 0.0243 0.0648
Schistosoma mansoni ABC transporter 0.0017 0.0106 0.0282
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0009 0.0038 0.0096
Brugia malayi photoreceptor-specific nuclear receptor 0.0009 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.0038 0.0277 0.3379
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0168 0.204
Plasmodium vivax telomerase reverse transcriptase, putative 0.0331 0.2704 1
Mycobacterium leprae putative cytochrome p450 0.0007 0.0021 0.5
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0108 0.0283
Echinococcus multilocularis mitogen activated protein kinase 0.0103 0.0816 0.1091
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0108 0.0142
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.0573 0.7008
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.002 0.0131 0.0351
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0526 0.1403
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.0002 0.0005
Brugia malayi jmjC domain containing protein 0.0014 0.008 0.0107
Brugia malayi MAP kinase sur-1 0.0103 0.0816 0.1122
Echinococcus granulosus JmjC domain containing protein 4 0.0014 0.008 0.0208
Echinococcus granulosus mitogen activated protein kinase 3 0.0103 0.0816 0.2175
Brugia malayi jmjC domain containing protein 0.0055 0.0419 0.0575
Brugia malayi ABC transporter family protein 0.0017 0.0106 0.0143
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0014 0.008 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0009 0.0038 0.0049
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0038 0.0101
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.0573 0.1529
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.0573 1
Leishmania major telomerase reverse transcriptase, putative 0.0331 0.2704 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.008 0.0955
Loa Loa (eye worm) jmjC domain-containing protein 0.0014 0.008 0.0955
Brugia malayi CXXC zinc finger family protein 0.0032 0.0228 0.0311
Brugia malayi Cytochrome P450 family protein 0.0025 0.0168 0.0229
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0131 0.0173
Loa Loa (eye worm) steroid hormone receptor 0.0009 0.0038 0.044
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0423 0.058
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0038 0.0101
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.0524 0.0699
Loa Loa (eye worm) hypothetical protein 0.0009 0.0038 0.044
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.002 0.0131 0.0411
Loa Loa (eye worm) hypothetical protein 0.0009 0.0038 0.044
Echinococcus multilocularis lysine specific demethylase 5A 0.0053 0.0404 0.0539

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.