Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0055 | 0.2272 | 0.3312 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0023 | 0.0688 | 0.1708 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0019 | 0.0453 | 0.0274 |
Loa Loa (eye worm) | fatty acid synthase | 0.0023 | 0.0659 | 0.0747 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0031 | 0.1072 | 0.1518 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0044 | 0.1687 | 0.2044 |
Toxoplasma gondii | hypothetical protein | 0.0023 | 0.0688 | 0.2084 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0016 | 0.0348 | 0.0849 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0023 | 0.0688 | 0.1708 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0033 | 0.1179 | 0.1678 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0033 | 0.1179 | 0.1408 |
Schistosoma mansoni | transient receptor potential channel | 0.0055 | 0.2272 | 0.3312 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0041 | 0.1553 | 0.6827 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0173 | 0.8046 | 1 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0034 | 0.1234 | 0.2168 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0023 | 0.0674 | 0.0776 |
Trypanosoma brucei | trypanothione reductase | 0.0041 | 0.1553 | 0.6827 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0021 | 0.06 | 0.06 |
Leishmania major | hypothetical protein, conserved | 0.0033 | 0.1179 | 0.4884 |
Mycobacterium ulcerans | lipase LipD | 0.0033 | 0.1179 | 0.1204 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.6748 | 1 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0034 | 0.1234 | 0.1234 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0093 | 0.4129 | 0.4129 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0015 | 0.0291 | 0.0066 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0033 | 0.1179 | 0.1179 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0093 | 0.4129 | 0.8823 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0034 | 0.1234 | 0.1234 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0068 | 0.2868 | 0.4201 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0023 | 0.0674 | 0.0557 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0173 | 0.8046 | 1 |
Onchocerca volvulus | 0.0033 | 0.1179 | 0.0778 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0688 | 0.0784 |
Leishmania major | hypothetical protein, conserved | 0.0023 | 0.0688 | 0.2334 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0041 | 0.1553 | 0.4999 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0033 | 0.1179 | 0.1179 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0093 | 0.4129 | 0.4129 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0024 | 0.0744 | 0.0744 |
Brugia malayi | Transient-receptor-potential like protein | 0.0031 | 0.1077 | 0.128 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0041 | 0.1553 | 0.1867 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0068 | 0.2868 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0041 | 0.1553 | 0.4999 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0014 | 0.0239 | 0.0453 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0033 | 0.1179 | 0.1204 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0081 | 0.3532 | 0.5194 |
Mycobacterium tuberculosis | Conserved protein | 0.0033 | 0.1179 | 0.1179 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0033 | 0.1179 | 0.1204 |
Brugia malayi | hypothetical protein | 0.0031 | 0.1072 | 0.1274 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1179 | 0.1398 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.094 | 0.1099 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0173 | 0.8046 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0033 | 0.1179 | 0.3576 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1179 | 0.1398 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0023 | 0.0688 | 0.2334 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.06 | 0.0683 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0033 | 0.1179 | 0.1179 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1444 | 0.173 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0024 | 0.0744 | 0.1043 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1072 | 0.1518 |
Brugia malayi | Thioredoxin reductase | 0.0041 | 0.1553 | 0.1876 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1179 | 0.1398 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0033 | 0.1179 | 0.4884 |
Brugia malayi | Probable ClpP-like protease | 0.0068 | 0.2868 | 0.3521 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0044 | 0.1722 | 0.2489 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0023 | 0.0674 | 0.0557 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0017 | 0.0355 | 0.0355 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0068 | 0.2868 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0044 | 0.1722 | 0.329 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0019 | 0.0485 | 0.0448 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0068 | 0.2868 | 1 |
Brugia malayi | beta-lactamase | 0.0033 | 0.1179 | 0.1408 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0033 | 0.1179 | 0.4884 |
Schistosoma mansoni | transient receptor potential channel | 0.0084 | 0.367 | 0.54 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0031 | 0.1072 | 0.1518 |
Brugia malayi | glutathione reductase | 0.0041 | 0.1553 | 0.1876 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0014 | 0.0239 | 0.0231 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2868 | 0.3514 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0023 | 0.0674 | 0.0557 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0031 | 0.1072 | 0.1518 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0015 | 0.0291 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1179 | 0.1398 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0173 | 0.8046 | 1 |
Echinococcus granulosus | geminin | 0.0146 | 0.6748 | 1 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0019 | 0.0453 | 0.0274 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0033 | 0.1179 | 0.1204 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0023 | 0.0674 | 0.0881 |
Mycobacterium ulcerans | thioesterase TesA | 0.0019 | 0.0485 | 0.0315 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0093 | 0.4129 | 0.4129 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0022 | 0.0639 | 0.0639 |
Trichomonas vaginalis | esterase, putative | 0.0033 | 0.1179 | 0.1204 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0068 | 0.2868 | 0.3367 |
Onchocerca volvulus | 0.0033 | 0.1179 | 0.0778 | |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.6748 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0033 | 0.1179 | 0.1678 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0044 | 0.1722 | 0.2489 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0023 | 0.0688 | 0.0913 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0068 | 0.2868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.1077 | 0.1271 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0041 | 0.1553 | 0.2237 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0023 | 0.0674 | 0.0674 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0033 | 0.1179 | 0.1204 |
Loa Loa (eye worm) | beta-lactamase | 0.0033 | 0.1179 | 0.1398 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0014 | 0.0239 | 0.0273 |
Mycobacterium leprae | conserved hypothetical protein | 0.0033 | 0.1179 | 0.2042 |
Brugia malayi | beta-lactamase family protein | 0.0033 | 0.1179 | 0.1408 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0044 | 0.1722 | 0.1722 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0084 | 0.367 | 0.54 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0023 | 0.0674 | 0.0674 |
Mycobacterium ulcerans | polyketide synthase | 0.0024 | 0.0744 | 0.0647 |
Onchocerca volvulus | 0.004 | 0.1512 | 0.1225 | |
Plasmodium vivax | glutathione reductase, putative | 0.0041 | 0.1553 | 0.4999 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.06 | 0.0673 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0023 | 0.0688 | 0.2334 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1179 | 0.1398 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0068 | 0.2868 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0041 | 0.1553 | 0.1867 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0033 | 0.1179 | 0.1179 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0093 | 0.4129 | 0.4129 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0023 | 0.0688 | 0.1709 |
Mycobacterium tuberculosis | Conserved protein | 0.0033 | 0.1179 | 0.1179 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0084 | 0.367 | 0.54 |
Mycobacterium tuberculosis | Conserved protein | 0.0033 | 0.1179 | 0.1179 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1179 | 0.1398 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0019 | 0.0468 | 0.0468 |
Brugia malayi | beta-lactamase family protein | 0.0033 | 0.1179 | 0.1408 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0033 | 0.1179 | 0.1179 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0024 | 0.0744 | 0.0744 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0041 | 0.1553 | 0.1553 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0044 | 0.1722 | 0.1722 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0055 | 0.2272 | 0.3312 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0053 | 0.2164 | 0.2465 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0055 | 0.2272 | 0.3312 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0014 | 0.0239 | 0.0273 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0053 | 0.2164 | 0.2465 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0033 | 0.1179 | 0.1398 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0023 | 0.0688 | 0.2334 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0033 | 0.1179 | 0.1678 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0024 | 0.0744 | 0.1043 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0173 | 0.8046 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0033 | 0.1179 | 0.2042 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0033 | 0.1179 | 0.1204 |
Brugia malayi | MH2 domain containing protein | 0.0104 | 0.4681 | 0.5789 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0033 | 0.1179 | 0.1204 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0068 | 0.2868 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0104 | 0.4641 | 0.4641 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0014 | 0.0239 | 0.0453 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0081 | 0.3532 | 0.5194 |
Leishmania major | hypothetical protein, conserved | 0.0053 | 0.2164 | 1 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0024 | 0.0744 | 0.0647 |
Onchocerca volvulus | 0.0173 | 0.8046 | 1 | |
Schistosoma mansoni | transient receptor potential channel | 0.0055 | 0.2272 | 0.3312 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0068 | 0.2868 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0023 | 0.0688 | 0.1709 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0031 | 0.1077 | 0.1526 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0104 | 0.4681 | 0.5785 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0013 | 0.0186 | 0.0186 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0104 | 0.4641 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0053 | 0.2164 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0068 | 0.2868 | 1 |
Trypanosoma brucei | low molecular weight protein tyrosine phosphatase, putative | 0.0053 | 0.2164 | 1 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0023 | 0.0674 | 0.0557 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.012 | 0.5425 | 0.5425 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0173 | 0.8046 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0093 | 0.4129 | 0.4129 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0033 | 0.1179 | 0.1179 |
Mycobacterium ulcerans | thioesterase | 0.0019 | 0.0485 | 0.0315 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0068 | 0.2868 | 0.4201 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0041 | 0.1553 | 0.2237 |
Toxoplasma gondii | ABC1 family protein | 0.0033 | 0.1179 | 0.3867 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0024 | 0.0744 | 0.1043 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0041 | 0.1583 | 0.132 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0104 | 0.4681 | 0.5785 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0176 | 0.0142 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0688 | 0.0793 |
Mycobacterium ulcerans | hypothetical protein | 0.0033 | 0.1179 | 0.1204 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0023 | 0.0674 | 0.0881 |
Onchocerca volvulus | 0.0033 | 0.1179 | 0.0778 | |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0019 | 0.0485 | 0.0485 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0014 | 0.0239 | 0.0273 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0022 | 0.0639 | 0.0639 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0019 | 0.0453 | 0.0373 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0034 | 0.1234 | 0.1274 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0104 | 0.4641 | 0.4641 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0023 | 0.0674 | 0.0674 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0014 | 0.0239 | 0.0239 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0068 | 0.2868 | 0.3367 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0024 | 0.0744 | 0.0647 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0024 | 0.0744 | 0.0744 |
Echinococcus multilocularis | geminin | 0.0146 | 0.6748 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0023 | 0.0688 | 0.2084 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0033 | 0.1179 | 0.1204 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0173 | 0.8046 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0033 | 0.1179 | 0.1204 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0033 | 0.1179 | 0.1678 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0033 | 0.1179 | 0.1179 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0031 | 0.1077 | 0.1526 |
Brugia malayi | hypothetical protein | 0.0015 | 0.0282 | 0.0285 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0053 | 0.2164 | 1 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0173 | 0.8046 | 1 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0015 | 0.0277 | 0.0589 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0023 | 0.0688 | 0.1708 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0173 | 0.8046 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0173 | 0.8046 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0068 | 0.2868 | 0.5924 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0173 | 0.8046 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.367 | 0.4518 |
Plasmodium falciparum | glutathione reductase | 0.0041 | 0.1553 | 0.4999 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0104 | 0.4641 | 0.4641 |
Mycobacterium tuberculosis | Probable reductase | 0.0093 | 0.4129 | 0.4129 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0023 | 0.0688 | 0.1709 |
Leishmania major | trypanothione reductase | 0.0041 | 0.1553 | 0.6827 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0024 | 0.0744 | 0.2288 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0055 | 0.2272 | 0.3312 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0033 | 0.1179 | 0.4884 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.2135 | 0.2595 |
Mycobacterium ulcerans | polyketide synthase | 0.0023 | 0.0674 | 0.0557 |
Toxoplasma gondii | thioredoxin reductase | 0.0041 | 0.1553 | 0.5225 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0173 | 0.8046 | 1 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0084 | 0.367 | 0.54 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0068 | 0.2868 | 0.4201 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.