Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | follicle stimulating hormone receptor | 0.0232 | 0.3708 | 0.827 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0232 | 0.3708 | 0.7308 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.0915 | 0.2041 |
Leishmania major | fucose kinase, putative | 0.0077 | 0.1017 | 0.1017 |
Trypanosoma cruzi | fucose kinase, putative | 0.0105 | 0.1498 | 0.1498 |
Brugia malayi | beta-lactamase | 0.0071 | 0.0915 | 0.2041 |
Brugia malayi | galactokinase family protein | 0.0277 | 0.4483 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0311 | 0.0311 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0087 | 0.0195 |
Trypanosoma brucei | mevalonate-diphosphate decarboxylase | 0.0077 | 0.1017 | 0.1557 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0311 | 0.0693 |
Entamoeba histolytica | galactokinase, putative | 0.0594 | 1 | 1 |
Echinococcus granulosus | diphosphomevalonate decarboxylase | 0.0077 | 0.1017 | 0.1017 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0071 | 0.0915 | 0.0915 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0071 | 0.0915 | 0.0915 |
Echinococcus multilocularis | Mevalonate galactokinase | 0.0182 | 0.2837 | 0.2837 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0183 | 0.028 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.021 | 0.3326 | 0.6555 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0311 | 0.0311 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0311 | 0.0693 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0311 | 0.0613 |
Schistosoma mansoni | ran | 0.0021 | 0.0049 | 0.009 |
Onchocerca volvulus | 0.0071 | 0.0915 | 0.1968 | |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0183 | 0.1999 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0311 | 0.0693 |
Trypanosoma cruzi | homoserine kinase | 0.0182 | 0.2837 | 0.2837 |
Trichomonas vaginalis | galactokinase, putative | 0.0077 | 0.1017 | 0.2269 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0071 | 0.0915 | 0.0915 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0311 | 0.5073 | 1 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.0087 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0915 | 0.1804 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0462 | 0.091 |
Trichomonas vaginalis | galactokinase, putative | 0.0277 | 0.4483 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0071 | 0.0915 | 0.0915 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0049 | 0.2705 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0071 | 0.0915 | 0.0915 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0049 | 0.011 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0311 | 0.0311 |
Trichomonas vaginalis | galactokinase, putative | 0.0277 | 0.4483 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0311 | 0.0311 |
Echinococcus granulosus | Mevalonate galactokinase | 0.0182 | 0.2837 | 0.2837 |
Trypanosoma cruzi | phosphomevalonate kinase protein, putative | 0.0077 | 0.1017 | 0.1017 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0244 | 0.0244 |
Brugia malayi | beta-lactamase family protein | 0.0071 | 0.0915 | 0.2041 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0057 | 0.0661 | 0.0661 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0071 | 0.0915 | 0.0915 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0915 | 0.1804 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0071 | 0.0915 | 0.1663 |
Leishmania major | homoserine kinase, putative | 0.0182 | 0.2837 | 0.2837 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0455 | 0.7584 | 0.7584 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0294 | 0.0294 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0183 | 0.0408 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0049 | 0.011 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0201 | 0.0365 |
Loa Loa (eye worm) | beta-lactamase | 0.0071 | 0.0915 | 0.1804 |
Toxoplasma gondii | GHMP kinase, N-terminal domain-containing protein | 0.0277 | 0.4483 | 1 |
Trypanosoma cruzi | mevalonate-diphosphate decarboxylase, putative | 0.0077 | 0.1017 | 0.1017 |
Leishmania major | phosphomevalonate kinase protein, putative | 0.0182 | 0.2837 | 0.2837 |
Treponema pallidum | hypothetical protein | 0.0182 | 0.2837 | 0.3276 |
Loa Loa (eye worm) | glutaminase | 0.0273 | 0.442 | 0.8713 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.0087 | 0.0087 |
Trypanosoma brucei | mevalonate kinase, putative | 0.0182 | 0.2837 | 0.4343 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0071 | 0.0915 | 0.2041 |
Mycobacterium leprae | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) | 0.0182 | 0.2837 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0201 | 0.0448 |
Onchocerca volvulus | 0.0077 | 0.1017 | 0.225 | |
Mycobacterium tuberculosis | Probable homoserine kinase ThrB | 0.0077 | 0.1017 | 0.1017 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0183 | 0.0183 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0294 | 0.0294 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.0915 | 0.0915 |
Mycobacterium leprae | Probable lipase LipE | 0.0071 | 0.0915 | 0.2586 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1017 | 0.2005 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0071 | 0.0915 | 0.14 |
Mycobacterium ulcerans | hypothetical protein | 0.0071 | 0.0915 | 0.0915 |
Schistosoma mansoni | galactokinase | 0.0277 | 0.4483 | 0.8149 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0311 | 0.1096 |
Schistosoma mansoni | mevalonate kinase | 0.0182 | 0.2837 | 0.5157 |
Trypanosoma cruzi | galactokinase, putative | 0.0517 | 0.866 | 0.866 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0462 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0915 | 0.1804 |
Leishmania major | hypothetical protein, conserved | 0.0071 | 0.0915 | 0.0915 |
Trichomonas vaginalis | importin beta-1, putative | 0.0024 | 0.0087 | 0.0195 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0201 | 0.0448 |
Trichomonas vaginalis | glutaminase, putative | 0.0273 | 0.442 | 0.986 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0294 | 0.0535 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0311 | 0.0476 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0201 | 0.0201 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0057 | 0.0661 | 0.0661 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0182 | 0.0182 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0294 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0915 | 0.1804 |
Mycobacterium ulcerans | beta-lactamase | 0.0071 | 0.0915 | 0.0915 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0087 | 0.0195 |
Schistosoma mansoni | diphosphomevalonate decarboxylase | 0.0077 | 0.1017 | 0.1849 |
Echinococcus multilocularis | diphosphomevalonate decarboxylase | 0.0077 | 0.1017 | 0.1017 |
Brugia malayi | diphosphomevalonate decarboxylase family protein | 0.0077 | 0.1017 | 0.2269 |
Trypanosoma brucei | mevalonate diphosphate decarboxylase | 0.0077 | 0.1017 | 0.1557 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0311 | 0.0693 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0071 | 0.0915 | 0.0915 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0087 | 0.0087 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0071 | 0.0915 | 0.0915 |
Onchocerca volvulus | 0.0071 | 0.0915 | 0.1968 | |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0057 | 0.0661 | 0.0661 |
Brugia malayi | Pre-SET motif family protein | 0.021 | 0.3326 | 0.7418 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0071 | 0.0915 | 0.0915 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.0915 | 0.0915 |
Mycobacterium ulcerans | glutaminase | 0.0273 | 0.442 | 0.442 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0311 | 0.0311 |
Trichomonas vaginalis | galactokinase, putative | 0.0105 | 0.1498 | 0.3341 |
Plasmodium vivax | hypothetical protein, conserved | 0.0071 | 0.0915 | 1 |
Chlamydia trachomatis | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0077 | 0.1017 | 0.5 |
Trypanosoma cruzi | galactokinase, putative | 0.0594 | 1 | 1 |
Mycobacterium ulcerans | phosphomevalonate kinase | 0.0182 | 0.2837 | 0.2837 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0462 | 0.0839 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0311 | 0.0311 |
Echinococcus granulosus | geminin | 0.0335 | 0.5502 | 0.5502 |
Trypanosoma brucei | phosphomevalonate kinase protein, putative | 0.0182 | 0.2837 | 0.4343 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 0.5502 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0077 | 0.1017 | 0.2269 |
Trypanosoma cruzi | homoserine kinase | 0.0182 | 0.2837 | 0.2837 |
Trichomonas vaginalis | galactokinase, putative | 0.0277 | 0.4483 | 1 |
Trypanosoma cruzi | galactokinase-like protein, putative | 0.0517 | 0.866 | 0.866 |
Leishmania major | fucose kinase, putative | 0.0077 | 0.1017 | 0.1017 |
Trichomonas vaginalis | galactokinase, putative | 0.0277 | 0.4483 | 1 |
Trypanosoma cruzi | galactokinase, putative | 0.0594 | 1 | 1 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0057 | 0.0661 | 0.1475 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0458 | 0.7634 | 0.7634 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.0915 | 0.2041 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0915 | 0.1804 |
Echinococcus granulosus | neuropeptide s receptor | 0.0458 | 0.7634 | 0.7634 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0071 | 0.0915 | 0.2041 |
Wolbachia endosymbiont of Brugia malayi | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0182 | 0.2837 | 1 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0049 | 0.011 |
Trypanosoma brucei | galactokinase-like protein, putative | 0.0395 | 0.6534 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0071 | 0.0915 | 0.0915 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.2837 | 0.5593 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0462 | 0.0462 |
Schistosoma mansoni | glutaminase | 0.0273 | 0.442 | 0.8034 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0049 | 0.0049 |
Toxoplasma gondii | GHMP kinase, putative | 0.0182 | 0.2837 | 0.6329 |
Giardia lamblia | Mevalonate kinase | 0.0182 | 0.2837 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0915 | 0.1804 |
Onchocerca volvulus | 0.0239 | 0.383 | 1 | |
Echinococcus multilocularis | galactokinase | 0.0594 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0294 | 0.0294 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0183 | 0.0183 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0462 | 0.0839 |
Brugia malayi | mevalonate kinase family protein | 0.0182 | 0.2837 | 0.6329 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0049 | 0.0049 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0183 | 0.028 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0057 | 0.0661 | 0.0661 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0183 | 0.0332 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0458 | 0.7634 | 0.7634 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0049 | 0.0049 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0071 | 0.0915 | 0.1663 |
Trypanosoma cruzi | fucose kinase, putative | 0.0105 | 0.1498 | 0.1498 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0462 | 0.0462 |
Trypanosoma cruzi | phosphomevalonate kinase protein, putative | 0.0077 | 0.1017 | 0.1017 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.0915 | 0.0915 |
Trichomonas vaginalis | set domain proteins, putative | 0.0239 | 0.383 | 0.8542 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0053 | 0.0595 | 0.1173 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | galactokinase | 0.0277 | 0.4483 | 0.8837 |
Loa Loa (eye worm) | glutaminase 2 | 0.0273 | 0.442 | 0.8713 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0057 | 0.0661 | 0.0661 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0049 | 0.0541 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0201 | 0.0365 |
Leishmania major | mevalonate kinase, putative | 0.0182 | 0.2837 | 0.2837 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0294 | 0.0657 |
Mycobacterium ulcerans | mevalonate kinase, Erg12 | 0.0182 | 0.2837 | 0.2837 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0049 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.2326 | 0.4585 |
Trypanosoma cruzi | mevalonate kinase, putative | 0.0182 | 0.2837 | 0.2837 |
Trichomonas vaginalis | diphosphomevalonate decarboxylase, putative | 0.0077 | 0.1017 | 0.2269 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0294 | 0.0535 |
Echinococcus multilocularis | N acetylgalactosamine kinase | 0.0277 | 0.4483 | 0.4483 |
Mycobacterium ulcerans | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0182 | 0.2837 | 0.2837 |
Onchocerca volvulus | 0.0071 | 0.0915 | 0.1968 | |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0311 | 0.0693 |
Leishmania major | mevalonate-diphosphate decarboxylase, putative | 0.0077 | 0.1017 | 0.1017 |
Echinococcus multilocularis | geminin | 0.0335 | 0.5502 | 0.5502 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0183 | 0.0408 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0458 | 0.7634 | 0.7634 |
Brugia malayi | beta-lactamase family protein | 0.0071 | 0.0915 | 0.2041 |
Trypanosoma brucei | homoserine kinase | 0.0182 | 0.2837 | 0.4343 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0311 | 0.0565 |
Giardia lamblia | Diphosphomevalonate decarboxylase | 0.0077 | 0.1017 | 0.3585 |
Brugia malayi | RNA, U transporter 1 | 0.0083 | 0.1115 | 0.2487 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0049 | 0.0049 |
Onchocerca volvulus | 0.0153 | 0.2326 | 0.5857 | |
Trichomonas vaginalis | mevalonate kinase, putative | 0.0077 | 0.1017 | 0.2269 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0311 | 0.0311 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0462 | 0.103 |
Trypanosoma cruzi | mevalonate-diphosphate decarboxylase, putative | 0.0077 | 0.1017 | 0.1017 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0049 | 0.0049 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0294 | 0.0294 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0201 | 0.0201 |
Mycobacterium ulcerans | galactokinase | 0.0594 | 1 | 1 |
Mycobacterium tuberculosis | Probable galactokinase GalK (galactose kinase) | 0.0594 | 1 | 1 |
Leishmania major | galactokinase-like protein | 0.0594 | 1 | 1 |
Treponema pallidum | galactokinase | 0.0517 | 0.866 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.0915 | 0.2041 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 0.5502 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0071 | 0.0915 | 0.0915 |
Mycobacterium leprae | conserved hypothetical protein | 0.0071 | 0.0915 | 0.2586 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0311 | 0.0565 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0201 | 0.0201 |
Mycobacterium ulcerans | diphosphomevalonate decarboxylase | 0.0077 | 0.1017 | 0.1017 |
Brugia malayi | hypothetical protein | 0.0153 | 0.2326 | 0.5189 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0049 | 0.0098 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0071 | 0.0915 | 0.0915 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0071 | 0.0915 | 0.0915 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0183 | 0.0361 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0057 | 0.0661 | 0.0661 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0294 | 0.0294 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0201 | 0.2194 |
Mycobacterium leprae | PROBABLE HOMOSERINE KINASE THRB | 0.0077 | 0.1017 | 0.298 |
Echinococcus granulosus | N acetylgalactosamine kinase | 0.0277 | 0.4483 | 0.4483 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0183 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0311 | 0.5073 | 0.9221 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0071 | 0.0915 | 0.2041 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0462 | 0.0839 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0201 | 0.0396 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0462 | 0.0462 |
Schistosoma mansoni | ran | 0.0021 | 0.0049 | 0.009 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0201 | 0.0365 |
Mycobacterium tuberculosis | Possible D-alpha-D-heptose-7-phosphate kinase HddA | 0.0182 | 0.2837 | 0.2837 |
Echinococcus multilocularis | snurportin 1 | 0.0311 | 0.5073 | 0.5073 |
Trichomonas vaginalis | esterase, putative | 0.0071 | 0.0915 | 0.2041 |
Brugia malayi | glutaminase DH11.1 | 0.0273 | 0.442 | 0.986 |
Mycobacterium ulcerans | lipase LipD | 0.0071 | 0.0915 | 0.0915 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0201 | 0.0365 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0057 | 0.0661 | 0.1202 |
Toxoplasma gondii | ABC1 family protein | 0.0071 | 0.0915 | 0.2041 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0071 | 0.0915 | 0.1804 |
Mycobacterium ulcerans | homoserine kinase | 0.0182 | 0.2837 | 0.2837 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0049 | 0.0174 |
Echinococcus granulosus | snurportin 1 | 0.0311 | 0.5073 | 0.5073 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 8 % | Antimalarial activity against Plasmodium berghei ANKA infected in C57BL/6J mouse assessed as parasitemia level at 5 mg/kg, po administered after 24 hrs post infection measured after 30 days in presence of 15 mg/kg of mefloquine hydrochloride relative to control | ChEMBL. | 24508128 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.