Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.1821 | 0.4556 | 0.4547 |
Leishmania major | phosphatidylinositol 4-kinase alpha, putative | 0.028 | 0.0455 | 0.044 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3084 | 0.7918 | 0.7918 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0458 | 0.0927 | 0.0927 |
Loa Loa (eye worm) | phosphatidylinositol kinase | 0.026 | 0.04 | 0.0385 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0386 | 0.0736 | 0.0721 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.3866 | 1 | 1 |
Echinococcus granulosus | phosphatidylinositol 4 kinase alpha | 0.028 | 0.0455 | 0.044 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1337 | 0.3267 | 0.3267 |
Trichomonas vaginalis | phosphatidylinositol 4-kinase, putative | 0.028 | 0.0455 | 0.0455 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3291 | 0.8469 | 0.8469 |
Trypanosoma cruzi | phosphatidylinositol kinase, putative | 0.026 | 0.04 | 0.0385 |
Loa Loa (eye worm) | phosphatidylinositol 4-kinase type 3 alpha isoform 1 | 0.028 | 0.0455 | 0.044 |
Plasmodium falciparum | phosphatidylinositol 3-kinase | 0.028 | 0.0455 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.1337 | 0.3267 | 0.3256 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.075 | 0.1706 | 0.1693 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 3, putative | 0.026 | 0.04 | 0.0385 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0322 | 0.0566 | 0.0551 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.0637 | 0.1404 | 0.1391 |
Trypanosoma brucei | phosphatidylinositol 4-kinase alpha, putative | 0.028 | 0.0455 | 0.044 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3084 | 0.7918 | 0.7918 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2108 | 0.5319 | 0.5319 |
Plasmodium vivax | phosphatidylinositol 3- and 4-kinase, putative | 0.026 | 0.04 | 0.8757 |
Plasmodium falciparum | phosphatidylinositol 3- and 4-kinase, putative | 0.026 | 0.04 | 0.8757 |
Echinococcus granulosus | serine protein kinase ATM | 0.075 | 0.1706 | 0.1693 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.075 | 0.1706 | 0.1706 |
Echinococcus multilocularis | DNA dependent protein kinase catalytic subunit | 0.0526 | 0.1109 | 0.1095 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2108 | 0.5319 | 0.5319 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2887 | 0.7393 | 0.7393 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.028 | 0.0455 | 0.044 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.3866 | 1 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0322 | 0.0566 | 0.0566 |
Toxoplasma gondii | phosphatidylinositol 3- and 4-kinase | 0.028 | 0.0455 | 0.0078 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.026 | 0.04 | 0.04 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0117 | 0.0021 | 0.0005 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2509 | 0.6387 | 0.6387 |
Loa Loa (eye worm) | hypothetical protein | 0.0779 | 0.1782 | 0.1769 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.049 | 0.1014 | 0.1014 |
Echinococcus granulosus | PIK kinase FAT and Armadillo domain containing protein | 0.0575 | 0.124 | 0.1226 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0128 | 0.0049 | 0.0033 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.1326 | 0.3237 | 0.3226 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0394 | 0.0757 | 0.0757 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1039 | 0.2474 | 0.2474 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.028 | 0.0455 | 0.044 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2305 | 0.5845 | 0.5845 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.026 | 0.04 | 0.04 |
Giardia lamblia | GTOR | 0.3866 | 1 | 1 |
Giardia lamblia | Phosphoinositide-3-kinase, class 3 | 0.0302 | 0.0511 | 0.0496 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.1337 | 0.3267 | 0.3256 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0322 | 0.0566 | 0.0551 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.3866 | 1 | 1 |
Entamoeba histolytica | protein kinase rad3, putative | 0.075 | 0.1706 | 0.1693 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0117 | 0.0021 | 0.0005 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.1378 | 0.3376 | 0.3366 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2312 | 0.5861 | 0.5861 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1326 | 0.3237 | 0.3237 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.1378 | 0.3376 | 0.3366 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0322 | 0.0566 | 0.0566 |
Echinococcus multilocularis | serine protein kinase ATM | 0.075 | 0.1706 | 0.1693 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0322 | 0.0566 | 0.0566 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.3866 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0386 | 0.0736 | 0.0721 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0344 | 0.0625 | 0.061 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0117 | 0.0021 | 0.0005 |
Echinococcus multilocularis | 0.026 | 0.04 | 0.0385 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0835 | 0.1932 | 0.1932 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.0198 | 0.0235 | 0.0219 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.3866 | 1 | 1 |
Entamoeba histolytica | phosphatidylinositol 4-kinase, putative | 0.028 | 0.0455 | 0.044 |
Leishmania major | hypothetical protein, conserved | 0.0354 | 0.0652 | 0.0637 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.1378 | 0.3376 | 0.3366 |
Plasmodium vivax | hypothetical protein | 0.026 | 0.04 | 0.8757 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0575 | 0.124 | 0.124 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.1378 | 0.3376 | 0.3366 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.3866 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1326 | 0.3237 | 0.3237 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.026 | 0.04 | 0.5 |
Echinococcus granulosus | serine:threonine protein kinase SMG1 | 0.075 | 0.1706 | 0.1693 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3084 | 0.7918 | 0.7918 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.1378 | 0.3376 | 0.3366 |
Leishmania major | phosphatidylinositol 4-kinase, putative | 0.026 | 0.04 | 0.0385 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.075 | 0.1706 | 0.1693 |
Loa Loa (eye worm) | hypothetical protein | 0.075 | 0.1706 | 0.1693 |
Giardia lamblia | Hypothetical protein | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2108 | 0.5319 | 0.5319 |
Trichomonas vaginalis | conserved hypothetical protein | 0.049 | 0.1014 | 0.1014 |
Echinococcus multilocularis | phosphatidylinositol 4 kinase alpha | 0.028 | 0.0455 | 0.044 |
Echinococcus granulosus | phosphatidylinositol 4 kinase beta | 0.026 | 0.04 | 0.0385 |
Entamoeba histolytica | hypothetical protein | 0.0416 | 0.0816 | 0.0801 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2887 | 0.7393 | 0.7393 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3866 | 1 | 1 |
Toxoplasma gondii | FATC domain-containing protein | 0.075 | 0.1706 | 0.1867 |
Schistosoma mansoni | hypothetical protein | 0.026 | 0.04 | 0.0385 |
Schistosoma mansoni | phosphatidylinositol 4-kinase type-II | 0.026 | 0.04 | 0.0385 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0322 | 0.0566 | 0.0551 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.075 | 0.1706 | 0.1693 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0458 | 0.0927 | 0.0912 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3084 | 0.7918 | 0.7918 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.026 | 0.04 | 0.0385 |
Onchocerca volvulus | 0.026 | 0.04 | 0.5 | |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.028 | 0.0455 | 0.0455 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2312 | 0.5861 | 0.5861 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0595 | 0.1294 | 0.128 |
Schistosoma mansoni | hypothetical protein | 0.0575 | 0.124 | 0.1226 |
Brugia malayi | phosphatidylinositol 4-kinase, catalytic, alpha polypeptide | 0.028 | 0.0455 | 0.044 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0458 | 0.0927 | 0.0912 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.3087 | 0.7926 | 0.7923 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0322 | 0.0566 | 0.0551 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0115 | 0.0016 | 0.0016 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2305 | 0.5845 | 0.5845 |
Plasmodium vivax | hypothetical protein, conserved | 0.026 | 0.04 | 0.8757 |
Schistosoma mansoni | phosphatidylinositol 3-kinase class | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2105 | 0.5311 | 0.5311 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0128 | 0.0049 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.049 | 0.1014 | 0.1 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0416 | 0.0816 | 0.0801 |
Plasmodium vivax | phosphatidylinositol 4-kinase, putative | 0.026 | 0.04 | 0.8757 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase vps34-like | 0.0322 | 0.0566 | 0.0551 |
Onchocerca volvulus | 0.026 | 0.04 | 0.5 | |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0386 | 0.0736 | 0.0721 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.3866 | 1 | 1 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.3866 | 1 | 1 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.0115 | 0.0016 | 0.5 |
Toxoplasma gondii | non-specific serine/threonine protein kinase | 0.0835 | 0.1932 | 0.219 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.3866 | 1 | 1 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase, putative | 0.026 | 0.04 | 0.0385 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0637 | 0.1404 | 0.1391 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0458 | 0.0927 | 0.0912 |
Plasmodium falciparum | phosphatidylinositol 4-kinase | 0.026 | 0.04 | 0.8757 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0761 | 0.1735 | 0.1735 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.3087 | 0.7926 | 0.7923 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.0637 | 0.1404 | 0.1391 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase, putative | 0.026 | 0.04 | 0.0385 |
Echinococcus granulosus | Phosphatidylinositol 4 kinase type 2 beta | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2887 | 0.7393 | 0.7393 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2594 | 0.6613 | 0.6613 |
Trichomonas vaginalis | immunophilin, putative | 0.0115 | 0.0016 | 0.0016 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.075 | 0.1706 | 0.1693 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2887 | 0.7393 | 0.7393 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.026 | 0.04 | 0.0385 |
Echinococcus granulosus | Phosphatidylinositol 4 kinase type 2 beta | 0.026 | 0.04 | 0.0385 |
Entamoeba histolytica | phosphatidylinositol-4,5-bisphosphate 3-kinase, putative | 0.028 | 0.0455 | 0.044 |
Toxoplasma gondii | phosphatidylinositol 3- and 4-kinase | 0.028 | 0.0455 | 0.0078 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.026 | 0.04 | 0.0385 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.028 | 0.0455 | 0.044 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3866 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.026 | 0.04 | 0.04 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.026 | 0.04 | 0.04 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2887 | 0.7393 | 0.7393 |
Schistosoma mansoni | fkbp-rapamycin associated protein | 0.075 | 0.1706 | 0.1693 |
Echinococcus granulosus | phosphatidylinositol 3 kinase catalytic subunit | 0.028 | 0.0455 | 0.044 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.1378 | 0.3376 | 0.3366 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.2887 | 0.7393 | 1 |
Echinococcus multilocularis | Phosphatidylinositol 4 kinase type 2 beta | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2312 | 0.5861 | 0.5861 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2105 | 0.5311 | 0.5311 |
Entamoeba histolytica | hypothetical protein | 0.026 | 0.04 | 0.0385 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2887 | 0.7393 | 0.7393 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.3866 | 1 | 1 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.3087 | 0.7926 | 0.7923 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.1932 | 0.1919 |
Plasmodium vivax | phosphatidylinositol 4-kinase, putative | 0.026 | 0.04 | 0.8757 |
Loa Loa (eye worm) | hypothetical protein | 0.0575 | 0.124 | 0.1226 |
Entamoeba histolytica | hypothetical protein | 0.075 | 0.1706 | 0.1693 |
Giardia lamblia | Phosphatidylinositol 4-kinase | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.0458 | 0.0927 | 0.0927 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0458 | 0.0927 | 0.0912 |
Brugia malayi | phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative | 0.0179 | 0.0186 | 0.0171 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0322 | 0.0566 | 0.0551 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.026 | 0.04 | 0.0385 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.3866 | 1 | 1 |
Plasmodium vivax | phosphatidylinositol 3-kinase, putative | 0.028 | 0.0455 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0394 | 0.0757 | 0.0757 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.1617 | 0.4014 | 0.4004 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1326 | 0.3237 | 0.3237 |
Entamoeba histolytica | Phosphatidylinositol 3- and 4-kinase family | 0.0761 | 0.1735 | 0.1722 |
Echinococcus multilocularis | PIK kinase, FAT and Armadillo domain containing protein | 0.0575 | 0.124 | 0.1226 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.028 | 0.0455 | 0.0455 |
Mycobacterium leprae | conserved hypothetical protein | 0.026 | 0.04 | 0.5 |
Brugia malayi | FAT domain containing protein | 0.0575 | 0.124 | 0.1226 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1326 | 0.3237 | 0.3237 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.3866 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.04 | 0.0385 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.028 | 0.0455 | 0.044 |
Schistosoma mansoni | phosphatidylinositol 4-kinase | 0.028 | 0.0455 | 0.044 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) | 0.0115 | 0.0016 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.075 | 0.1706 | 0.1706 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2887 | 0.7393 | 0.7393 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.049 | 0.1014 | 0.1 |
Echinococcus multilocularis | Zinc finger, PHD finger | 0.028 | 0.0455 | 0.044 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.075 | 0.1706 | 0.1693 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0386 | 0.0736 | 0.0721 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0115 | 0.0016 | 0.0016 |
Giardia lamblia | Phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.0352 | 0.0646 | 0.0631 |
Entamoeba histolytica | hypothetical protein | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.0458 | 0.0927 | 0.0927 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0117 | 0.0021 | 0.0005 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3866 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2105 | 0.5311 | 0.5311 |
Leishmania major | phosphatidylinositol kinase, putative | 0.026 | 0.04 | 0.0385 |
Echinococcus multilocularis | Phosphatidylinositol 4 kinase type 2 beta | 0.026 | 0.04 | 0.0385 |
Echinococcus granulosus | DNA dependent protein kinase catalytic subunit | 0.0526 | 0.1109 | 0.1095 |
Leishmania major | hypothetical protein, unknown function | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.0115 | 0.0016 | 0.0016 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2108 | 0.5319 | 0.5319 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.026 | 0.04 | 0.0385 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3084 | 0.7918 | 0.7918 |
Trypanosoma brucei | phosphatidylinositol 3-kinase catalytic subunit, putative | 0.026 | 0.04 | 0.0385 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.1326 | 0.3237 | 0.3226 |
Echinococcus multilocularis | serine:threonine protein kinase SMG1 | 0.075 | 0.1706 | 0.1693 |
Entamoeba histolytica | hypothetical protein | 0.026 | 0.04 | 0.0385 |
Schistosoma mansoni | phosphatidylinositol 4-kinase | 0.026 | 0.04 | 0.0385 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.075 | 0.1706 | 0.1693 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.1337 | 0.3267 | 0.3256 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ratio (binding) | = 0.29 | Inhibition of MBI-D-resistant Magnaporthe oryzae SW (OYU-1) scytalone dehydratase Val75Met mutant assessed as metabolism ratio of scytalone at 75 nM at 30 degC in presence of 50 mM PIPES | ChEMBL. | No reference |
Ratio (binding) | = 0.36 | Inhibition of wild type Magnaporthe oryzae Hoku-1 scytalone dehydratase assessed as metabolism ratio of scytalone at 75 nM at 30 degC in presence of 50 mM PIPES | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.