Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | thymidine kinase, putative | 0.0282 | 0.253 | 0.828 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0398 | 0.126 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0024 | 0.0013 | 0.0042 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0084 | 0.0595 | 0.1802 |
Mycobacterium tuberculosis | Possible maturase | 0.0024 | 0.0013 | 0.0039 |
Brugia malayi | RNase H family protein | 0.0101 | 0.0761 | 0.2491 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0024 | 0.0013 | 0.0042 |
Plasmodium vivax | DNA polymerase zeta catalytic subunit, putative | 0.0142 | 0.1167 | 0.3528 |
Trypanosoma cruzi | DNA polymerase epsilon catalytic subunit, putative | 0.0142 | 0.1167 | 0.1804 |
Trichomonas vaginalis | NeSL-1_NeSL reverse transcriptases, putative | 0.0024 | 0.0013 | 0.0042 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.0138 | 0.0438 |
Loa Loa (eye worm) | DNA-directed DNA polymerase III | 0.0336 | 0.3055 | 0.9675 |
Plasmodium falciparum | thymidylate kinase | 0.0087 | 0.0631 | 0.1689 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | DNA polymerase epsilon catalytic subunit, putative | 0.0142 | 0.1167 | 0.1167 |
Toxoplasma gondii | hypothetical protein | 0.0111 | 0.086 | 0.2475 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.0398 | 0.1302 |
Brugia malayi | DNA polymerase family B containing protein | 0.0142 | 0.1167 | 0.382 |
Echinococcus granulosus | thymidylate kinase | 0.0087 | 0.0631 | 0.2065 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0037 | 0.0138 | 0.0418 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.05 | 0.0774 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Echinococcus multilocularis | DNA polymerase alpha catalytic subunit | 0.0277 | 0.2479 | 0.8114 |
Loa Loa (eye worm) | DNA polymerase epsilon catalytic subunit | 0.0079 | 0.0551 | 0.1744 |
Entamoeba histolytica | DNA polymerase delta catalytic subunit, putative | 0.0336 | 0.3055 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0551 | 0.1744 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0037 | 0.0143 | 0.0468 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0087 | 0.0631 | 0.1965 |
Trypanosoma brucei | RNA helicase, putative | 0.1049 | 1 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.0138 | 0.0138 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0101 | 0.0761 | 0.1176 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0362 | 0.3304 | 1 |
Brugia malayi | DNA polymerase family B, exonuclease domain containing protein | 0.0142 | 0.1167 | 0.382 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Trypanosoma brucei | DNA polymerase delta catalytic subunit, putative | 0.0336 | 0.3055 | 0.3055 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Onchocerca volvulus | DNA polymerase alpha catalytic subunit homolog | 0.0347 | 0.3158 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0124 | 0.0992 | 0.0992 |
Leishmania major | DNA polymerase epsilon catalytic subunit, putative | 0.0142 | 0.1167 | 0.1804 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0093 | 0.0686 | 0.2077 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0124 | 0.0992 | 0.0992 |
Brugia malayi | RNase H family protein | 0.0101 | 0.0761 | 0.2491 |
Trichomonas vaginalis | DNA polymerase zeta catalytic subunit, putative | 0.0336 | 0.3055 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0084 | 0.0595 | 0.1802 |
Leishmania major | ribonuclease H1, putative | 0.0101 | 0.0761 | 0.1176 |
Giardia lamblia | CDC8 | 0.0087 | 0.0631 | 0.2065 |
Schistosoma mansoni | DNA polymerase delta catalytic subunit | 0.0336 | 0.3055 | 0.3055 |
Schistosoma mansoni | phosphoglucomutase | 0.0101 | 0.0761 | 0.0761 |
Echinococcus multilocularis | ribonuclease H1 | 0.0101 | 0.0761 | 0.2491 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0087 | 0.0631 | 0.3897 |
Trypanosoma cruzi | DNA polymerase zeta catalytic subunit, putative | 0.0063 | 0.0398 | 0.0615 |
Mycobacterium ulcerans | thymidylate kinase | 0.0087 | 0.0631 | 0.1909 |
Leishmania major | DNA polymerase I alpha catalytic subunit, putative | 0.0172 | 0.1458 | 0.2253 |
Brugia malayi | DNA polymerase delta catalytic subunit | 0.0336 | 0.3055 | 1 |
Plasmodium vivax | DNA polymerase epsilon, catalytic subunit a, putative | 0.0142 | 0.1167 | 0.3528 |
Brugia malayi | DNA polymerase alpha catalytic subunit | 0.0242 | 0.2137 | 0.6993 |
Brugia malayi | RNase H family protein | 0.0101 | 0.0761 | 0.2491 |
Trichomonas vaginalis | DNA polymerase II, putative | 0.0172 | 0.1458 | 0.4771 |
Echinococcus multilocularis | DNA polymerase zeta catalytic subunit | 0.0142 | 0.1167 | 0.382 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0087 | 0.0631 | 0.2065 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.0975 |
Brugia malayi | Zinc knuckle family protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0686 | 0.647 | 0.647 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0024 | 0.0013 | 0.0042 |
Giardia lamblia | DNA polymerase delta, catalytic subunit | 0.0336 | 0.3055 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0325 | 0.2947 | 0.2947 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Echinococcus multilocularis | DNA polymerase delta catalytic subunit | 0.0336 | 0.3055 | 1 |
Plasmodium falciparum | DNA polymerase delta catalytic subunit | 0.0336 | 0.3055 | 1 |
Schistosoma mansoni | thymidylate kinase | 0.0087 | 0.0631 | 0.0631 |
Trichomonas vaginalis | DNA polymerase delta catalytic subunit, putative | 0.0142 | 0.1167 | 0.382 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.0101 | 0.0761 | 0.2379 |
Trypanosoma brucei | SLACS reverse transcriptase, putative | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma brucei | DNA polymerase zeta catalytic subunit, putative | 0.0142 | 0.1167 | 0.1167 |
Brugia malayi | Zinc knuckle family protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0084 | 0.0595 | 0.1802 |
Schistosoma mansoni | protein kinase | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0034 | 0.0115 | 0.0177 |
Plasmodium vivax | DNA polymerase alpha, putative | 0.0242 | 0.2137 | 0.6851 |
Echinococcus granulosus | dna polymerase epsilon catalytic subunit a | 0.0142 | 0.1167 | 0.382 |
Onchocerca volvulus | DNA polymerase homolog | 0.0142 | 0.1167 | 0.367 |
Plasmodium falciparum | DNA polymerase alpha catalytic subunit A | 0.0093 | 0.0688 | 0.1886 |
Onchocerca volvulus | DNA polymerase delta catalytic subunit homolog | 0.0336 | 0.3055 | 0.9673 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0067 | 0.0438 | 0.0677 |
Toxoplasma gondii | DNA polymerase family B protein | 0.0063 | 0.0398 | 0.089 |
Brugia malayi | glutathione reductase | 0.0037 | 0.0138 | 0.0452 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.0115 | 0.0177 |
Toxoplasma gondii | DNA polymerase | 0.0336 | 0.3055 | 1 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0282 | 0.253 | 0.391 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.0631 |
Plasmodium falciparum | DNA polymerase zeta catalytic subunit, putative | 0.0063 | 0.0398 | 0.089 |
Echinococcus multilocularis | hypothetical protein | 0.0115 | 0.0899 | 0.2943 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.002 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0093 | 0.0686 | 0.2077 |
Brugia malayi | reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0686 | 0.647 | 1 |
Schistosoma mansoni | DNA polymerase alpha catalytic subunit | 0.0277 | 0.2479 | 0.2479 |
Echinococcus granulosus | DNA polymerase zeta catalytic subunit | 0.0142 | 0.1167 | 0.382 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0325 | 0.2947 | 0.4555 |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.0138 | 0.0438 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0013 | 0.0013 |
Trichomonas vaginalis | reverse transcriptase [C. elegans], putative | 0.0024 | 0.0013 | 0.0042 |
Schistosoma mansoni | DNA polymerase zeta catalytic subunit | 0.0142 | 0.1167 | 0.1167 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.0138 | 0.0452 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0097 | 0.0722 | 0.1116 |
Leishmania major | DNA polymerase zeta catalytic subunit, putative | 0.0063 | 0.0398 | 0.0615 |
Giardia lamblia | DNA polymerase alpha subunit A | 0.0198 | 0.171 | 0.5596 |
Plasmodium vivax | DNA polymerase delta catalytic subunit, putative | 0.0336 | 0.3055 | 1 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.05 | 0.0774 |
Trichomonas vaginalis | DNA polymerase alpha catalytic subunit, putative | 0.0172 | 0.1458 | 0.4771 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0024 | 0.0013 | 0.0042 |
Chlamydia trachomatis | thymidylate kinase | 0.0087 | 0.0631 | 0.5 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Echinococcus granulosus | ribonuclease H1 | 0.0101 | 0.0761 | 0.2491 |
Schistosoma mansoni | thymidylate kinase | 0.0087 | 0.0631 | 0.0631 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0686 | 0.647 | 1 |
Echinococcus multilocularis | dna polymerase epsilon catalytic subunit a | 0.0142 | 0.1167 | 0.382 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0282 | 0.253 | 0.828 |
Trypanosoma brucei | Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.05 | 0.0774 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | thymidine kinase | 0.0282 | 0.253 | 0.253 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.2065 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.05 | 0.0774 |
Echinococcus multilocularis | thymidylate kinase | 0.0087 | 0.0631 | 0.2065 |
Trypanosoma brucei | unspecified product | 0.0124 | 0.0992 | 0.0992 |
Schistosoma mansoni | DNA polymerase alpha catalytic subunit | 0.007 | 0.046 | 0.046 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Toxoplasma gondii | DNA polymerase (pol2) superfamily protein | 0.0242 | 0.2137 | 0.6851 |
Toxoplasma gondii | thymidylate kinase | 0.0087 | 0.0631 | 0.1689 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0282 | 0.253 | 0.391 |
Entamoeba histolytica | DNA polymerase zeta catalytic subunit, putative | 0.0063 | 0.0398 | 0.1302 |
Trypanosoma brucei | SLACS retrotransposable element (part), putative | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.0899 | 0.2847 |
Trichomonas vaginalis | DNA polymerase alpha catalytic subunit, putative | 0.0142 | 0.1167 | 0.382 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0097 | 0.0722 | 0.1116 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.0631 |
Schistosoma mansoni | DNA polymerase gamma | 0.0115 | 0.0899 | 0.0899 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | DNA polymerase epsilon catalytic subunit, putative | 0.0142 | 0.1167 | 0.1804 |
Trypanosoma cruzi | DNA polymerase delta catalytic subunit, putative | 0.0336 | 0.3055 | 0.4722 |
Onchocerca volvulus | DNA polymerase epsilon catalytic subunit A homolog | 0.0142 | 0.1167 | 0.367 |
Trypanosoma brucei | ribonuclease H1 | 0.0101 | 0.0761 | 0.0761 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0118 | 0.0927 | 0.1434 |
Schistosoma mansoni | phosphoglucomutase | 0.0101 | 0.0761 | 0.0761 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.2065 |
Brugia malayi | thymidylate kinase | 0.0087 | 0.0631 | 0.2065 |
Toxoplasma gondii | DNA polymerase family B protein | 0.0142 | 0.1167 | 0.3528 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0101 | 0.0761 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.0631 | 0.0631 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Schistosoma mansoni | DNA polymerase epsilon catalytic subunit | 0.0142 | 0.1167 | 0.1167 |
Trypanosoma cruzi | DNA polymerase delta catalytic subunit, putative | 0.0257 | 0.2286 | 0.3533 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0101 | 0.0761 | 0.1176 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0013 | 0.0042 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0084 | 0.0595 | 0.1802 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0097 | 0.0722 | 0.0722 |
Echinococcus granulosus | DNA polymerase delta catalytic subunit | 0.0336 | 0.3055 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0097 | 0.0722 | 0.1116 |
Trichomonas vaginalis | DNA polymerase alpha catalytic subunit, putative | 0.0079 | 0.0551 | 0.1802 |
Giardia lamblia | Thymidine kinase | 0.0282 | 0.253 | 0.828 |
Plasmodium falciparum | DNA polymerase epsilon catalytic subunit A, putative | 0.0079 | 0.0551 | 0.1414 |
Giardia lamblia | DNA polymerase epsilon, catalytic subunit | 0.0142 | 0.1167 | 0.382 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0398 | 0.126 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | DNA polymerase I alpha catalytic subunit, putative | 0.0172 | 0.1458 | 0.2253 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.05 | 0.0774 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0124 | 0.0992 | 0.0992 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0034 | 0.0115 | 0.0177 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0074 | 0.05 | 0.0774 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.0975 |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.0076 | 0.0249 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Loa Loa (eye worm) | hypothetical protein | 0.0347 | 0.3158 | 1 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Leishmania major | trypanothione reductase | 0.0037 | 0.0138 | 0.0214 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0024 | 0.0013 | 0.0042 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0101 | 0.0761 | 0.2491 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0325 | 0.2947 | 0.4555 |
Mycobacterium ulcerans | hypothetical protein | 0.0362 | 0.3304 | 1 |
Schistosoma mansoni | scy1(yeast) protein kinase-like | 0.0024 | 0.0013 | 0.0013 |
Giardia lamblia | Reverse transcriptase/endonuclease | 0.0024 | 0.0013 | 0.0042 |
Echinococcus granulosus | DNA polymerase subunit gamma | 0.0115 | 0.0899 | 0.2943 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Giardia lamblia | Ribonuclease H | 0.0101 | 0.0761 | 0.2491 |
Entamoeba histolytica | thymidine kinase, putative | 0.0282 | 0.253 | 0.828 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0551 | 0.1744 |
Leishmania major | thymidylate kinase-like protein | 0.0087 | 0.0631 | 0.0975 |
Brugia malayi | DNA polymerase I family protein | 0.0115 | 0.0899 | 0.2943 |
Mycobacterium tuberculosis | Probable reductase | 0.0084 | 0.0595 | 0.1802 |
Trichomonas vaginalis | reverse transcriptases, putative | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0058 | 0.0347 | 0.0536 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.0138 | 0.0214 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.05 | 0.0774 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0013 | 0.0013 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0037 | 0.0143 | 0.0468 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0093 | 0.0686 | 0.2077 |
Plasmodium vivax | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.1689 |
Trichomonas vaginalis | reverse transcriptases, putative | 0.0024 | 0.0013 | 0.0042 |
Echinococcus granulosus | KRAB A domain containing protein | 0.0024 | 0.0013 | 0.0042 |
Loa Loa (eye worm) | DNA polymerase epsilon catalytic subunit | 0.0063 | 0.0398 | 0.126 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Trypanosoma brucei | DNA polymerase alpha catalytic subunit | 0.0172 | 0.1458 | 0.1458 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.0076 | 0.0241 |
Brugia malayi | reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Loa Loa (eye worm) | thymidylate kinase | 0.0087 | 0.0631 | 0.1998 |
Entamoeba histolytica | DNA polymerase alpha catalytic subunit, putative | 0.0093 | 0.0688 | 0.2253 |
Brugia malayi | reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0101 | 0.0761 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0093 | 0.0686 | 1 |
Toxoplasma gondii | ribonuclease HI protein | 0.0101 | 0.0761 | 0.2135 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0087 | 0.0631 | 0.1909 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0084 | 0.0595 | 0.1802 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0282 | 0.253 | 0.828 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0024 | 0.0013 | 0.0013 |
Schistosoma mansoni | phosphoglucomutase | 0.0101 | 0.0761 | 0.0761 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Echinococcus granulosus | DNA polymerase alpha catalytic subunit | 0.0277 | 0.2479 | 0.8114 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0124 | 0.0992 | 0.0992 |
Leishmania major | thymidine kinase, putative | 0.0282 | 0.253 | 0.391 |
Leishmania major | DNA polymerase delta catalytic subunit, putative | 0.0336 | 0.3055 | 0.4722 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0686 | 0.647 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.