Detailed information for compound 227793

Basic information

Technical information
  • TDR Targets ID: 227793
  • Name: methyl 5-[6-(dimethylamino)-1-(4-methoxy-3-me thoxycarbonyl-5-methylphenyl)-6-oxohex-1-enyl ]-2-methoxy-3-methylbenzoate
  • MW: 497.58 | Formula: C28H35NO7
  • H donors: 0 H acceptors: 3 LogP: 4.88 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1cc(cc(c1OC)C)C(=CCCCC(=O)N(C)C)c1cc(C)c(c(c1)C(=O)OC)OC
  • InChi: 1S/C28H35NO7/c1-17-13-19(15-22(25(17)33-5)27(31)35-7)21(11-9-10-12-24(30)29(3)4)20-14-18(2)26(34-6)23(16-20)28(32)36-8/h11,13-16H,9-10,12H2,1-8H3
  • InChiKey: ZKYNQXWZCSUVDN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • methyl 5-[6-(dimethylamino)-1-(4-methoxy-3-methoxycarbonyl-5-methyl-phenyl)-6-oxo-hex-1-enyl]-2-methoxy-3-methyl-benzoate
  • 5-[6-(dimethylamino)-1-(4-methoxy-3-methoxycarbonyl-5-methylphenyl)-6-oxohex-1-enyl]-2-methoxy-3-methylbenzoic acid methyl ester
  • 5-[1-(3-carbomethoxy-4-methoxy-5-methyl-phenyl)-6-(dimethylamino)-6-keto-hex-1-enyl]-2-methoxy-3-methyl-benzoic acid methyl ester
  • methyl 5-[6-dimethylamino-1-(4-methoxy-3-methoxycarbonyl-5-methylphenyl)-6-oxohex-1-enyl]-2-methoxy-3-methylbenzoate
  • methyl 5-[6-dimethylamino-1-(4-methoxy-3-methoxycarbonyl-5-methyl-phenyl)-6-oxo-hex-1-enyl]-2-methoxy-3-methyl-benzoate
  • 5-[6-dimethylamino-1-(4-methoxy-3-methoxycarbonyl-5-methylphenyl)-6-oxohex-1-enyl]-2-methoxy-3-methylbenzoic acid methyl ester
  • 5-[1-(3-carbomethoxy-4-methoxy-5-methyl-phenyl)-6-dimethylamino-6-keto-hex-1-enyl]-2-methoxy-3-methyl-benzoic acid methyl ester
  • AIDS-165212
  • Alkenyldiarylmethanes (ADAM) 29a
  • AIDS165212
  • Methyl 5-{5-(N,N-dimethylcarbamoyl)-1-[3-methyl-4-methoxy-5-(methoxycarbonyl)phenyl]pent-1-enyl}-3--methyl-2-methoxybenzoate

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 reverse transcriptase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni hypothetical protein Get druggable targets OG5_139608 All targets in OG5_139608
Plasmodium yoelii integrase-related Get druggable targets OG5_139608 All targets in OG5_139608
Trypanosoma congolense RNA helicase, putative Get druggable targets OG5_139608 All targets in OG5_139608
Trypanosoma brucei RNA helicase, putative Get druggable targets OG5_139608 All targets in OG5_139608
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0181 0.1463
Loa Loa (eye worm) hypothetical protein 0.0031 0.0211 0.074
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0363 0.1108
Mycobacterium ulcerans hypothetical protein 0.0041 0.0363 0.5446
Echinococcus granulosus lamin dm0 0.0031 0.0211 0.021
Brugia malayi Doublecortin family protein 0.002 0.005 0.0174
Schistosoma mansoni lamin 0.0031 0.0211 0.021
Mycobacterium tuberculosis Conserved protein 0.0041 0.0363 0.1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0666 1
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0211 0.074
Loa Loa (eye worm) hypothetical protein 0.0041 0.0363 0.1274
Loa Loa (eye worm) hypothetical protein 0.0034 0.0263 0.0923
Trichomonas vaginalis ribonuclease H1, putative 0.0027 0.0151 0.0462
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0666 1
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0459 0.1612
Schistosoma mansoni rab6-interacting 0.002 0.005 0.0049
Schistosoma mansoni kinesin eg-5 0.0027 0.0152 0.0152
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0363 0.1108
Mycobacterium tuberculosis Conserved protein 0.0041 0.0363 0.1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0429 0.0429
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.1358 0.3744
Trypanosoma brucei unspecified product 0.0029 0.0185 0.1494
Trypanosoma cruzi ribonuclease H1, putative 0.0027 0.0151 0.3295
Brugia malayi Thioredoxin reductase 0.0047 0.0459 0.1612
Mycobacterium tuberculosis Conserved protein 0.0041 0.0363 0.1
Mycobacterium tuberculosis Probable reductase 0.0108 0.1358 0.3744
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0459 0.0459
Echinococcus multilocularis microtubule associated protein 2 0.0693 1 1
Trypanosoma brucei ingi protein (ORF1) 0.0029 0.0185 0.1494
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0429 0.0429
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.1358 0.3744
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.02 0.02
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.1358 0.8478
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0497 0.1746
Mycobacterium ulcerans beta-lactamase 0.0041 0.0363 0.5446
Loa Loa (eye worm) hypothetical protein 0.005 0.0497 0.1746
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.2846 1
Schistosoma mansoni lamin 0.0031 0.0211 0.021
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.02 0.4358
Plasmodium vivax SET domain protein, putative 0.003 0.02 0.4358
Giardia lamblia Ribonuclease H 0.0027 0.0151 0.9945
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0181 0.3943
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0429 0.0429
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0211 0.074
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0459 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0 0.5
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0429 0.0429
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0429 0.1508
Schistosoma mansoni hypothetical protein 0.002 0.005 0.0049
Schistosoma mansoni hypothetical protein 0.01 0.1236 0.1236
Brugia malayi RNase H family protein 0.0027 0.0151 0.0532
Onchocerca volvulus Ribonuclease H1 homolog 0.0027 0.0151 0.0316
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0459 0.1265
Brugia malayi hypothetical protein 0.002 0.005 0.0174
Schistosoma mansoni polycystin 1-related 0.002 0.005 0.0049
Brugia malayi beta-lactamase 0.0041 0.0363 0.1274
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0174
Brugia malayi Kinesin motor domain containing protein 0.0027 0.0152 0.0535
Onchocerca volvulus 0.0031 0.0211 0.05
Toxoplasma gondii ribonuclease HI protein 0.0027 0.0151 0.3295
Echinococcus multilocularis lamin 0.0031 0.0211 0.021
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.1358 0.3744
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0181 0.3943
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0363 0.1
Loa Loa (eye worm) hypothetical protein 0.003 0.02 0.0703
Toxoplasma gondii thioredoxin reductase 0.0047 0.0459 1
Onchocerca volvulus 0.0041 0.0363 0.0971
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0666 0.2339
Schistosoma mansoni hypothetical protein 0.0179 0.2404 0.2404
Loa Loa (eye worm) doublecortin family protein 0.002 0.005 0.0174
Brugia malayi Pre-SET motif family protein 0.003 0.02 0.0703
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.1358 0.3744
Trypanosoma cruzi ribonuclease H1, putative 0.0027 0.0151 0.3295
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0363 0.1274
Trichomonas vaginalis set domain proteins, putative 0.0238 0.3273 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0576 0.0576
Plasmodium falciparum glutathione reductase 0.0047 0.0459 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0429 0.1508
Brugia malayi beta-lactamase family protein 0.0041 0.0363 0.1274
Echinococcus granulosus RUN 0.002 0.005 0.0049
Loa Loa (eye worm) beta-lactamase 0.0041 0.0363 0.1274
Brugia malayi RNase H family protein 0.0027 0.0151 0.0532
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0666 0.0666
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0429 0.0429
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0185 0.1494
Loa Loa (eye worm) glutathione reductase 0.0047 0.0459 0.1612
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0576 0.0576
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0363 0.1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.1358 0.3744
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0262 0.3627 1
Brugia malayi hypothetical protein 0.0019 0.0031 0.0108
Plasmodium falciparum kinesin-5 0.0027 0.0152 0.3314
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0429 0.0429
Onchocerca volvulus 0.0238 0.3273 1
Schistosoma mansoni microtubule-associated protein tau 0.0693 1 1
Echinococcus granulosus kinesin family 1 0.0206 0.2799 0.2799
Trypanosoma brucei ingi protein (ORF1) 0.0029 0.0185 0.1494
Echinococcus multilocularis musashi 0.0031 0.0211 0.021
Echinococcus multilocularis RUN 0.002 0.005 0.0049
Echinococcus multilocularis kinesin family 1 0.0206 0.2799 0.2799
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0363 0.1
Schistosoma mansoni intermediate filament proteins 0.0031 0.0211 0.021
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.02 0.02
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0027 0.0151 1
Brugia malayi MH2 domain containing protein 0.0119 0.1511 0.5309
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0174
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0666 0.0666
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0363 0.0362
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0363 0.0362
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0211 0.074
Trypanosoma brucei RNA helicase, putative 0.01 0.1236 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.1537 0.4237
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0363 0.1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.1537 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0363 0.1274
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0363 0.5446
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0363 0.0362
Schistosoma mansoni loxhd1 0.002 0.005 0.0049
Schistosoma mansoni phosphoglucomutase 0.0027 0.0151 0.0151
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0429 0.0429
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.005 0.0049
Plasmodium falciparum LCCL domain-containing protein 0.002 0.005 0.1078
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.02 0.02
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0363 0.7903
Schistosoma mansoni phosphoglucomutase 0.0027 0.0151 0.0151
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0363 0.1108
Brugia malayi glutathione reductase 0.0047 0.0459 0.1612
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0181 0.3943
Giardia lamblia Kinesin-5 0.0027 0.0152 1
Schistosoma mansoni phosphoglucomutase 0.0027 0.0151 0.0151
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.005 0.0049
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.005 0.0049
Brugia malayi RNase H family protein 0.0027 0.0151 0.0532
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0263 0.0923
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0181 0.3943
Echinococcus multilocularis lamin dm0 0.0031 0.0211 0.021
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0363 0.1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.1537 0.4237
Echinococcus granulosus intermediate filament protein 0.0031 0.0211 0.021
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0363 0.7903
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0551 0.1936
Onchocerca volvulus 0.003 0.02 0.0467
Onchocerca volvulus 0.0031 0.0211 0.05
Leishmania major hypothetical protein, conserved 0.0029 0.0181 0.2717
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0666 1
Leishmania major ribonuclease H1, putative 0.0027 0.0151 0.2271
Loa Loa (eye worm) hypothetical protein 0.0041 0.0363 0.1274
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0184 0.0184
Leishmania major trypanothione reductase 0.0047 0.0459 0.689
Loa Loa (eye worm) hypothetical protein 0.0041 0.0363 0.1274
Mycobacterium ulcerans lipase LipD 0.0041 0.0363 0.5446
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0363 0.2934
Echinococcus granulosus ribonuclease H1 0.0027 0.0151 0.0151
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.1537 0.4237
Brugia malayi intermediate filament protein 0.0031 0.0211 0.074
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.005 0.0049
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0497 0.1746
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0363 0.1
Trypanosoma brucei ribonuclease H1 0.0027 0.0151 0.1223
Brugia malayi Pre-SET motif family protein 0.0209 0.2846 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0363 0.1274
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0 0.0001
Brugia malayi hypothetical protein 0.002 0.005 0.0174
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0363 0.7903
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.1511 0.5309
Loa Loa (eye worm) hypothetical protein 0.0029 0.0181 0.0636
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0459 1
Entamoeba histolytica kinesin, putative 0.0027 0.0152 0.5
Toxoplasma gondii ABC1 family protein 0.0041 0.0363 0.7903
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0041 0.0363 0.1274
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0666 0.1835
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0181 0.3943
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.005 0.0049
Plasmodium vivax glutathione reductase, putative 0.0047 0.0459 1
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.005 0.0049
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0459 0.0459
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0363 0.1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0497 0.1746
Schistosoma mansoni lipoxygenase 0.002 0.005 0.0049
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0363 0.0362
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.02 0.02
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0181 0.3943
Echinococcus multilocularis ribonuclease H1 0.0027 0.0151 0.0151
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0363 0.5446
Loa Loa (eye worm) hypothetical protein 0.0041 0.0363 0.1274
Leishmania major hypothetical protein, conserved 0.0041 0.0363 0.5446
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0363 0.1108
Schistosoma mansoni lipoxygenase 0.0055 0.0576 0.0576
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0029 0.0185 0.1494
Treponema pallidum ribonuclease H (rnhA) 0.0027 0.0151 1
Echinococcus granulosus lamin 0.0031 0.0211 0.021
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.02 0.02
Trichomonas vaginalis esterase, putative 0.0041 0.0363 0.1108
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.02 0.02
Onchocerca volvulus 0.0041 0.0363 0.0971
Plasmodium vivax kinesin-5 0.0027 0.0152 0.3314
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0363 0.1108
Brugia malayi hypothetical protein 0.0029 0.0181 0.0636
Trypanosoma brucei trypanothione reductase 0.0047 0.0459 0.3712
Onchocerca volvulus 0.0041 0.0363 0.0971
Toxoplasma gondii kinesin motor domain-containing protein 0.0027 0.0152 0.3314
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.1511 0.5309
Loa Loa (eye worm) hypothetical protein 0.003 0.0202 0.0711
Plasmodium falciparum thioredoxin reductase 0.0047 0.0459 1
Schistosoma mansoni hypothetical protein 0.0034 0.0263 0.0263
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.005 0.1078
Loa Loa (eye worm) kinesin-like protein KLP2 0.0027 0.0152 0.0535
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0666 0.0666
Brugia malayi beta-lactamase family protein 0.0041 0.0363 0.1274
Schistosoma mansoni rab6-interacting 0.002 0.005 0.0049

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) = 7.4 uM Concentration required for cytotoxicity against mock infected CEM-SS cells ChEMBL. 11708913
CC50 (functional) = 7.4 uM Concentration required for cytotoxicity against mock infected CEM-SS cells ChEMBL. 11708913
EC50 (functional) = 1.51 uM Inhibitory concentration for cytopathicity of HIV-1RF in CEM-SS cells ChEMBL. 11708913
IC50 (binding) = 5.65 uM Inhibitory activity against HIV-1 Reverse Transcriptase with rCdG as the template primer ChEMBL. 11708913
IC50 (binding) = 5.65 uM Inhibitory activity against HIV-1 Reverse Transcriptase with rCdG as the template primer ChEMBL. 11708913
TI (ADMET) = 4.91 Ratio of CC50/EC50 was determined ChEMBL. 11708913

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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