Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | smad | 0.0009 | 0.004 | 0.004 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Brugia malayi | Smad1 | 0.0009 | 0.004 | 0.004 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.004 | 0.004 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Onchocerca volvulus | 0.0041 | 0.0574 | 0.172 | |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.004 | 0.004 |
Brugia malayi | Matrixin family protein | 0.0056 | 0.0821 | 0.0821 |
Loa Loa (eye worm) | malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0043 | 0.0043 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.001 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0821 | 0.0821 |
Onchocerca volvulus | 0.0079 | 0.1215 | 0.3638 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0115 | 0.1822 | 0.1822 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0047 | 0.0671 | 0.0671 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0043 | 0.000000000075023 |
Brugia malayi | SWIRM domain containing protein | 0.0041 | 0.0574 | 0.0574 |
Echinococcus granulosus | L lactate dehydrogenase | 0.0365 | 0.6066 | 0.6066 |
Leishmania major | malate dehydrogenase, putative | 0.0596 | 1 | 1 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0041 | 0.0574 | 0.0534 |
Schistosoma mansoni | malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Plasmodium falciparum | lactate dehydrogenase, putative | 0.0232 | 0.3813 | 0.3787 |
Trypanosoma cruzi | glycosomal malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0041 | 0.0574 | 0.0534 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.004 | 0.004 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.001 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0574 | 0.0574 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0041 | 0.0574 | 0.0534 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.1198 | 0.1198 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.2683 | 0.2683 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0056 | 0.0821 | 0.0821 |
Brugia malayi | Protein kinase domain containing protein | 0.0047 | 0.0671 | 0.0671 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.001 | 0.0049 | 0.0146 |
Echinococcus granulosus | lactate dehydrogenase a | 0.0596 | 1 | 1 |
Echinococcus granulosus | L lactate dehydrogenase B chain | 0.0596 | 1 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0043 | 0.0043 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.004 | 0.004 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.2351 | 0.2351 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.004 | 0.004 |
Loa Loa (eye worm) | matrixin family protein | 0.0134 | 0.2158 | 0.2158 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.1215 | 0.1215 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0036 | 0.0493 | 0.0493 |
Trypanosoma cruzi | glycosomal malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.004 | 0.004 |
Brugia malayi | hypothetical protein | 0.001 | 0.0049 | 0.0049 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0144 | 0.0102 |
Trypanosoma brucei | cytosolic malate dehydrogenase | 0.0232 | 0.3813 | 1 |
Schistosoma mansoni | amine oxidase | 0.0041 | 0.0574 | 0.0574 |
Echinococcus multilocularis | 0.0045 | 0.0647 | 0.0647 | |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0043 | 0.0043 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0079 | 0.1212 | 0.1212 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.004 | 0.004 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0079 | 0.1212 | 0.1212 |
Echinococcus multilocularis | GPCR, family 2 | 0.0036 | 0.0493 | 0.0493 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.004 | 0.004 |
Entamoeba histolytica | malate dehydrogenase, putative | 0.0596 | 1 | 1 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0047 | 0.0671 | 0.0671 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.004 | 0.004 |
Brugia malayi | Matrixin family protein | 0.0056 | 0.0821 | 0.0821 |
Onchocerca volvulus | Matrilysin homolog | 0.0123 | 0.1969 | 0.5896 |
Leishmania major | glycosomal malate dehydrogenase | 0.0232 | 0.3813 | 0.3756 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0041 | 0.0574 | 0.0433 |
Echinococcus multilocularis | bloom syndrome protein | 0.0023 | 0.0276 | 0.0276 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0041 | 0.0574 | 0.0574 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0036 | 0.0493 | 0.0493 |
Entamoeba histolytica | recQ family helicase, putative | 0.0013 | 0.0091 | 0.0091 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0036 | 0.0493 | 0.0493 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0043 | 0.0043 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0041 | 0.0574 | 0.1506 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.2351 | 0.2351 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0139 | 0.2244 | 0.2244 |
Brugia malayi | Probable malate dehydrogenase, mitochondrial precursor | 0.0232 | 0.3813 | 0.3813 |
Schistosoma mansoni | amine oxidase | 0.0041 | 0.0574 | 0.0574 |
Echinococcus granulosus | bloom syndrome protein | 0.0023 | 0.0276 | 0.0276 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.004 | 0.004 |
Mycobacterium ulcerans | malate dehydrogenase | 0.0232 | 0.3813 | 0.3526 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0146 | 0.236 | 0.236 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0043 | 0.0043 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.004 | 0.004 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.1207 | 0.1207 |
Echinococcus multilocularis | L lactate dehydrogenase | 0.0365 | 0.6066 | 0.6066 |
Echinococcus multilocularis | L lactate dehydrogenase B chain | 0.0596 | 1 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0036 | 0.0493 | 0.0493 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.001 | 0.0049 | 0.0049 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0023 | 0.0276 | 0.0724 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0493 | 0.0493 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0202 | 0.3306 | 0.3306 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.1198 | 0.1198 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0113 | 0.1795 | 0.4708 |
Mycobacterium leprae | PROBABLE HYDROLASE | 0.0068 | 0.1027 | 0.1396 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Echinococcus granulosus | malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.001 | 0.0049 | 0.0049 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0541 | 0.9063 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.2351 | 0.2351 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0493 | 0.0493 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.001 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0821 | 0.0821 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0582 | 0.9759 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0574 | 0.0574 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Schistosoma mansoni | dishevelled | 0.001 | 0.0049 | 0.0049 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.001 | 0.0049 | 0.0049 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.001 | 0.0049 | 0.0049 |
Brugia malayi | Matrixin family protein | 0.0056 | 0.0821 | 0.0821 |
Schistosoma mansoni | L-lactate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0115 | 0.1822 | 0.1822 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0574 | 0.0574 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.001 | 0.0049 | 0.0049 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0041 | 0.0574 | 0.0574 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0023 | 0.0276 | 0.0276 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0574 | 0.0433 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0574 | 0.0433 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0036 | 0.0493 | 0.0493 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0146 | 0.236 | 0.236 |
Echinococcus granulosus | malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.1879 | 0.1879 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.2683 | 0.2683 |
Plasmodium vivax | lactate/malate dehydrogenase, putative | 0.0232 | 0.3813 | 0.3721 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0091 | 0.0238 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.1198 | 0.1198 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0041 | 0.0574 | 0.0574 |
Trypanosoma cruzi | cytosolic malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Toxoplasma gondii | lactate dehydrogenase LDH1 | 0.0596 | 1 | 1 |
Onchocerca volvulus | 0.001 | 0.0049 | 0.0146 | |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0078 | 0.1207 | 0.1207 |
Brugia malayi | Matrixin family protein | 0.0056 | 0.0821 | 0.0821 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Leishmania major | mitochondrial malate dehydrogenase | 0.0232 | 0.3813 | 0.3756 |
Trypanosoma cruzi | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0041 | 0.0574 | 0.0574 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0041 | 0.0574 | 0.0534 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0115 | 0.1822 | 0.1822 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.001 | 0.0049 | 0.0049 |
Toxoplasma gondii | hypothetical protein | 0.001 | 0.0049 | 0.0006 |
Schistosoma mansoni | tyrosine kinase | 0.0146 | 0.236 | 0.236 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.001 | 0.0049 | 0.0049 |
Onchocerca volvulus | 0.0056 | 0.0821 | 0.2459 | |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.2351 | 0.2351 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.001 | 0.0049 | 0.0049 |
Schistosoma mansoni | L-lactate dehydrogenase | 0.0596 | 1 | 1 |
Echinococcus granulosus | cytosolic malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0113 | 0.1795 | 0.4708 |
Schistosoma mansoni | malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Wolbachia endosymbiont of Brugia malayi | malate dehydrogenase | 0.0596 | 1 | 0.5 |
Entamoeba histolytica | malate dehydrogenase,cytoplasmic, putative | 0.0232 | 0.3813 | 0.3813 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.334 | 0.334 |
Toxoplasma gondii | lactate dehydrogenase LDH2 | 0.0596 | 1 | 1 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0204 | 0.334 | 1 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.001 | 0.0049 | 0.0049 |
Schistosoma mansoni | tyrosine kinase | 0.0079 | 0.1212 | 0.1212 |
Echinococcus multilocularis | cytosolic malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Toxoplasma gondii | malate dehydrogenase MDH | 0.0596 | 1 | 1 |
Echinococcus granulosus | lactate dehydrogenase a | 0.0596 | 1 | 1 |
Plasmodium falciparum | L-lactate dehydrogenase | 0.0596 | 1 | 1 |
Trypanosoma cruzi | mitochondrial malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0493 | 0.0493 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.001 | 0.0049 | 0.0049 |
Echinococcus multilocularis | malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Entamoeba histolytica | malate dehydrogenase, putative | 0.0232 | 0.3813 | 0.3813 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.1822 | 0.1822 |
Echinococcus granulosus | cytosolic malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Schistosoma mansoni | dep domain containing protein | 0.001 | 0.0049 | 0.0049 |
Mycobacterium leprae | PROBABLE MALATE DEHYDROGENASE MDH | 0.0232 | 0.3813 | 1 |
Leishmania major | malate dehydrogenase, putative | 0.0232 | 0.3813 | 0.3756 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0228 | 0.0186 |
Trypanosoma cruzi | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0574 | 0.0574 |
Echinococcus multilocularis | insulin receptor | 0.0047 | 0.0671 | 0.0671 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0023 | 0.0276 | 0.0724 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0091 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0049 | 0.0049 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0596 | 1 | 1 |
Schistosoma mansoni | malate dehydrogenase | 0.0596 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0493 | 0.0493 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0493 | 0.0493 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0043 | 0.0043 |
Echinococcus multilocularis | cytosolic malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0123 | 0.1969 | 0.5896 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0596 | 1 | 1 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0041 | 0.0574 | 0.1506 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1207 | 0.1207 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0146 | 0.236 | 0.236 |
Trypanosoma brucei | mitochondrial malate dehydrogenase | 0.0232 | 0.3813 | 1 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.001 | 0.0049 | 0.0049 |
Plasmodium vivax | malate dehydrogenase, putative | 0.0596 | 1 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.004 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0821 | 0.0821 |
Leishmania major | UDP-galactopyranose mutase | 0.0041 | 0.0574 | 0.0488 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.001 | 0.0049 | 0.0049 |
Echinococcus granulosus | geminin | 0.0165 | 0.2683 | 0.2683 |
Trypanosoma brucei | malate dehydrogenase-related | 0.0232 | 0.3813 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0043 | 0.0043 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Plasmodium vivax | lactate dehydrogenase | 0.0596 | 1 | 1 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.004 | 0.004 |
Schistosoma mansoni | regulator of G protein signaling | 0.001 | 0.0049 | 0.0049 |
Echinococcus multilocularis | malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Echinococcus granulosus | GPCR family 2 | 0.0036 | 0.0493 | 0.0493 |
Schistosoma mansoni | dishevelled | 0.001 | 0.0049 | 0.0049 |
Brugia malayi | Matrixin family protein | 0.0134 | 0.2158 | 0.2158 |
Echinococcus granulosus | insulin receptor | 0.0047 | 0.0671 | 0.0671 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.001 | 0.0049 | 0.0049 |
Trypanosoma cruzi | cytosolic malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Mycobacterium tuberculosis | Probable peptidoglycan hydrolase | 0.0068 | 0.1027 | 0.0533 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0582 | 0.9759 | 1 |
Echinococcus multilocularis | 0.0041 | 0.0574 | 0.0574 | |
Brugia malayi | hypothetical protein | 0.0041 | 0.0574 | 0.0574 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0041 | 0.0574 | 0.0534 |
Echinococcus multilocularis | lactate dehydrogenase protein | 0.0596 | 1 | 1 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0041 | 0.0574 | 0.0433 |
Brugia malayi | Hemopexin family protein | 0.0079 | 0.1215 | 0.1215 |
Schistosoma mansoni | malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0018 | 0.0192 | 0.0192 |
Leishmania major | malate dehydrogenase | 0.0232 | 0.3813 | 0.3756 |
Brugia malayi | Malate dehydrogenase, cytoplasmic | 0.0232 | 0.3813 | 0.3813 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0139 | 0.2244 | 0.2244 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.2351 | 0.2351 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Schistosoma mansoni | smad | 0.0009 | 0.004 | 0.004 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0041 | 0.0574 | 0.0574 |
Trypanosoma brucei | glycosomal malate dehydrogenase | 0.0232 | 0.3813 | 1 |
Mycobacterium tuberculosis | Probable malate dehydrogenase Mdh | 0.0232 | 0.3813 | 0.3815 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0043 | 0.0043 |
Schistosoma mansoni | tyrosine kinase | 0.0047 | 0.0671 | 0.0671 |
Mycobacterium ulcerans | hydrolase | 0.0068 | 0.1027 | 0.0492 |
Giardia lamblia | Malate dehydrogenase | 0.0232 | 0.3813 | 1 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.0081 | 0.1256 | 0.1256 |
Schistosoma mansoni | tyrosine kinase | 0.0079 | 0.1212 | 0.1212 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0041 | 0.0574 | 0.0574 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Onchocerca volvulus | Matrilysin homolog | 0.0056 | 0.0821 | 0.2459 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0036 | 0.0493 | 0.0493 |
Echinococcus granulosus | lactate dehydrogenase protein | 0.0596 | 1 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0079 | 0.1212 | 0.1212 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0574 | 0.0574 |
Echinococcus multilocularis | smad | 0.0009 | 0.004 | 0.004 |
Loa Loa (eye worm) | malate dehydrogenase | 0.0232 | 0.3813 | 0.3813 |
Loa Loa (eye worm) | RecQ helicase | 0.0023 | 0.0276 | 0.0276 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.004 | 0.004 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0232 | 0.3813 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0036 | 0.0493 | 0.0493 |
Schistosoma mansoni | tyrosine kinase | 0.0047 | 0.0671 | 0.0671 |
Brugia malayi | N-terminal motif family protein | 0.0204 | 0.334 | 0.334 |
Brugia malayi | DIX domain containing protein | 0.001 | 0.0049 | 0.0049 |
Chlamydia trachomatis | malate dehydrogenase | 0.0232 | 0.3813 | 1 |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0056 | 0.0821 | 0.0821 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0043 | 0.0043 |
Brugia malayi | MH2 domain containing protein | 0.0139 | 0.2244 | 0.2244 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0041 | 0.0574 | 0.0574 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0068 | 0.1027 | 0.1027 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1027 | 0.1027 |
Schistosoma mansoni | z-protein (S1r protein) | 0.001 | 0.0049 | 0.0049 |
Leishmania major | cytosolic malate dehydrogenase | 0.0232 | 0.3813 | 0.3756 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.004 | 0.004 |
Brugia malayi | hypothetical protein | 0.001 | 0.0049 | 0.0049 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.004 | 0.004 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0596 | 1 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.004 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0574 | 0.0574 |
Plasmodium falciparum | malate dehydrogenase | 0.0596 | 1 | 1 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0146 | 0.236 | 0.236 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.2351 | 0.2351 |
Echinococcus multilocularis | geminin | 0.0165 | 0.2683 | 0.2683 |
Loa Loa (eye worm) | matrixin family protein | 0.0123 | 0.1969 | 0.1969 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0202 | 0.3306 | 0.3306 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.004 | 0.004 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0047 | 0.0671 | 0.0671 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | 0 mM | Inhibitory constant against carbonic anhydrase IV ; nt= not tested | ChEMBL. | 15357993 |
Ki (binding) | NT 0 mM | Inhibition constant of anion against human carbonic anhydrase isozyme hCA IX | ChEMBL. | 15501038 |
Ki (binding) | = 1.78 mM | Inhibition of human recombinant CA7 | ChEMBL. | 16621537 |
Ki (functional) | = 6.8 mM | Inhibitory constant against Zn-Cam (Methanosarcina thermophila) | ChEMBL. | 15357993 |
Ki (binding) | = 8.4 mM | Inhibitory constant against carbonic anhydrase I | ChEMBL. | 15357993 |
Ki (binding) | = 8.4 mM | Inhibition constant of anion against human carbonic anhydrase isozyme hCA I | ChEMBL. | 15501038 |
Ki (binding) | = 16 mM | Inhibition constant of anion against human carbonic anhydrase isozyme hCA V | ChEMBL. | 15501038 |
Ki (binding) | = 30.8 mM | Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV | ChEMBL. | 15501038 |
Ki (binding) | = 44.8 mM | Inhibitory constant against methanoarchaeon Methanobacterium thermoautotrophicum (Cab) | ChEMBL. | 15357993 |
Ki (binding) | = 63 mM | Inhibitory constant against carbonic anhydrase II | ChEMBL. | 15357993 |
Ki (binding) | = 63 mM | Inhibition constant of anion against human carbonic anhydrase isozyme hCA II | ChEMBL. | 15501038 |
Ki (binding) | = 8.4 nM | Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli | ChEMBL. | 15454240 |
Ki (binding) | = 12.6 nM | Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10 | ChEMBL. | 15454240 |
Ki (binding) | = 16 nM | Inhibitory activity against human carbonic anhydrase V expressed in Escherichia coli | ChEMBL. | 15454240 |
Ki (binding) | = 63 nM | Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli | ChEMBL. | 15454240 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
8 literature references were collected for this gene.