Detailed information for compound 326808

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 402.909 | Formula: C23H26ClFNO2-
  • H donors: 1 H acceptors: 2 LogP: 4.61 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)C(=O)CCCN1C2CCC1CC(C2)(O)c1ccccc1.[Cl-]
  • InChi: 1S/C23H26FNO2.ClH/c24-19-10-8-17(9-11-19)22(26)7-4-14-25-20-12-13-21(25)16-23(27,15-20)18-5-2-1-3-6-18;/h1-3,5-6,8-11,20-21,27H,4,7,12-16H2;1H/p-1
  • InChiKey: RMASMVQBPUHBKK-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.007 0.0092
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0511 0.0658
Brugia malayi follicle stimulating hormone receptor 0.0027 0.0154 0.0326
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0271 0.0202
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0271 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0524 0.0578
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0154 0.0326
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0265 0.0412
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0524 0.0674
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0154 0.0197
Schistosoma mansoni hypothetical protein 0.0052 0.0436 0.0558
Schistosoma mansoni cpg binding protein 0.0031 0.0203 0.0259
Schistosoma mansoni amine GPCR 0.0027 0.0154 0.0195
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0265 0.0412
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0271 0.1718
Onchocerca volvulus 0.0027 0.016 0.001
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0068 0.0146
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0265 0.0338
Onchocerca volvulus 0.048 0.5303 0.7358
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0154 0.0169
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0339 0.0321
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0034 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0154 0.0195
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0154 0.0331
Schistosoma mansoni hypothetical protein 0.0027 0.0154 0.0195
Brugia malayi GnHR receptor homolog 0.0027 0.0154 0.0326
Brugia malayi Dopamine receptor protein 1 0.0027 0.0154 0.0326
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0524 0.9586
Loa Loa (eye worm) intermediate filament protein 0.0027 0.016 0.0345
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Brugia malayi hypothetical protein 0.0027 0.0154 0.0326
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0544 0.0697
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0154 0.0326
Schistosoma mansoni hypothetical protein 0.0027 0.0154 0.0195
Echinococcus multilocularis jumonji domain containing protein 0.0083 0.0788 0.0869
Brugia malayi CXXC zinc finger family protein 0.0029 0.0184 0.0393
Echinococcus multilocularis cpg binding protein 0.0031 0.0203 0.0224
Loa Loa (eye worm) inositol-1 0.0037 0.0271 0.0583
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0154 0.0195
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0265 0.0247
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0271 0.0253
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0265 0.0412
Mycobacterium ulcerans hypothetical protein 0.0287 0.3112 0.6421
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0154 0.0195
Schistosoma mansoni cpg binding protein 0.0029 0.0184 0.0234
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0154 0.0326
Schistosoma mansoni lamin 0.0027 0.016 0.0203
Schistosoma mansoni ap endonuclease 0.0019 0.007 0.0087
Brugia malayi Pre-SET motif family protein 0.0422 0.4642 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0433 0.0478
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0154 0.0326
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0433 0.0555
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.016 0.0345
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0894 1 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0247 0.0531
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0154 0.0169
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0154 0.0195
Schistosoma mansoni hypothetical protein 0.0698 0.7776 1
Schistosoma mansoni hypothetical protein 0.0027 0.0154 0.0195
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0091 0.0485
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0068 0.0085
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0304 0.0216
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0544 0.07
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0024 0.0006
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0154 0.0331
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0016 0.0035
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0059 0.0041
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0068 0.0085
Brugia malayi sulfakinin receptor protein 0.0027 0.0154 0.0326
Onchocerca volvulus 0.0037 0.0265 0.0159
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0179 0.0227
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Brugia malayi Pre-SET motif family protein 0.0061 0.0544 0.1168
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0071 0.0023
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0154 0.0331
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0154 0.0169
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0154 0.0197
Mycobacterium ulcerans transglutaminase family protein 0.0287 0.3112 0.6421
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0271 0.1718
Echinococcus granulosus intermediate filament protein 0.0027 0.016 0.0206
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0194 0.2057 0.2268
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0685 0.0879
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0027 0.0154 0.0195
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.1247 0.1604
Echinococcus multilocularis survival motor neuron protein 1 0.0253 0.2719 0.2997
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0154 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0172 0.0154
Loa Loa (eye worm) hypothetical protein 0.0019 0.0068 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0304 0.0287
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0265 0.0567
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0068 0.0087
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0154 0.0197
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0154 0.0169
Echinococcus multilocularis sex peptide receptor 0.0027 0.0154 0.0169
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0154 0.0197
Schistosoma mansoni hypothetical protein 0.0419 0.4605 0.5921
Brugia malayi AKH receptor 0.0027 0.0154 0.0326
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0154 0.0197
Schistosoma mansoni survival motor neuron protein 0.0052 0.0436 0.0558
Treponema pallidum fructose-bisphosphate aldolase 0.0894 1 1
Brugia malayi Dopamine receptor protein 2 0.0027 0.0154 0.0326
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0584 0.0748
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0544 0.0697
Onchocerca volvulus 0.0073 0.0677 0.0747
Schistosoma mansoni neuropeptide receptor 0.0027 0.0154 0.0195
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0154 0.0169
Onchocerca volvulus Alhambra homolog 0.0059 0.0524 0.053
Schistosoma mansoni hypothetical protein 0.0037 0.0269 0.0343
Plasmodium vivax SET domain protein, putative 0.0061 0.0544 1
Plasmodium falciparum phd finger protein, putative 0.0059 0.0524 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0154 0.0169
Echinococcus granulosus GPCR family 2 0.0016 0.0034 0.0044
Echinococcus multilocularis lamin dm0 0.0027 0.016 0.0177
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.1247 0.1602
Brugia malayi Serotonin receptor 0.0027 0.0154 0.0326
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0059 0.0041
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0068 0.0085
Schistosoma mansoni neuropeptide f receptor 76f 0.0027 0.0154 0.0195
Brugia malayi hypothetical protein 0.0027 0.0154 0.0326
Schistosoma mansoni amine GPCR 0.0027 0.0154 0.0195
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0154 0.0197
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0247 0.0527
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0154 0.0169
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0027 0.0154 0.0195
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0071 0.0023
Brugia malayi beta-lactamase family protein 0.0037 0.0265 0.0567
Brugia malayi G protein-coupled receptor 0.0027 0.0154 0.0326
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0265 0.0247
Mycobacterium ulcerans putative transglutaminase-like protein 0.0287 0.3112 0.6421
Echinococcus multilocularis neuropeptide receptor A26 0.0027 0.0154 0.0169
Echinococcus granulosus chromobox protein 1 0.0071 0.066 0.0849
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.1247 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0154 0.0197
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0154 0.0331
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0154 0.0169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0544 0.06
Brugia malayi hypothetical protein 0.0027 0.0154 0.0326
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0304 0.0287
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0154 0.0326
Onchocerca volvulus 0.0037 0.0265 0.0159
Brugia malayi hypothetical protein 0.0027 0.0154 0.0326
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0068 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0154 0.0169
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0154 0.0331
Brugia malayi chromobox protein homolog 3 0.004 0.0304 0.0652
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0433 0.0557
Brugia malayi hypothetical protein 0.0027 0.0154 0.0326
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0027 0.0154 0.0331
Echinococcus multilocularis neuropeptide s receptor 0.0027 0.0154 0.0169
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.007 0.0052
Schistosoma mansoni histamine h1 receptor 0.0027 0.0154 0.0195
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0068 0.0085
Echinococcus granulosus cpg binding protein 0.0031 0.0203 0.0262
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0154 0.0326
Echinococcus multilocularis lamin 0.0027 0.016 0.0177
Echinococcus granulosus chromobox protein 1 0.0071 0.066 0.0849
Entamoeba histolytica hypothetical protein 0.0037 0.0269 0.02
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0265 0.0084
Echinococcus multilocularis peregrin 0.0059 0.0524 0.0578
Brugia malayi putative neuropeptide receptor 0.0027 0.0154 0.0326
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0544 0.06
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0433 0.0555
Loa Loa (eye worm) hypothetical protein 0.0061 0.0544 0.1172
Brugia malayi AF-10 protein 0.0019 0.0071 0.0148
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0154 0.0195
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0227 0.0331
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.1247 0.2484
Mycobacterium ulcerans beta-lactamase 0.0037 0.0265 0.0412
Brugia malayi hypothetical protein 0.0027 0.0154 0.0326
Loa Loa (eye worm) jmjC domain-containing protein 0.0123 0.1242 0.2675
Trichomonas vaginalis set domain proteins, putative 0.048 0.5303 0.5294
Trichomonas vaginalis peptide N-glycanase, putative 0.0287 0.3112 0.31
Brugia malayi hypothetical protein 0.0027 0.0154 0.0326
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0154 0.0169
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0433 0.093
Schistosoma mansoni hypothetical protein 0.0016 0.0034 0.0041
Brugia malayi Serotonin receptor 0.0027 0.0154 0.0326
Schistosoma mansoni hypothetical protein 0.0027 0.0154 0.0195
Brugia malayi jmjC domain containing protein 0.0019 0.0068 0.0142
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0034 0.0037
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0016 0.0031
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.007 0.015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0068 0.0146
Giardia lamblia Hypothetical protein 0.0287 0.3112 0.3064
Echinococcus multilocularis musashi 0.0027 0.016 0.0177
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0154 0.0197
Loa Loa (eye worm) hypothetical protein 0.0037 0.0265 0.0571
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.007 0.0039
Echinococcus granulosus sex peptide receptor 0.0027 0.0154 0.0197
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0154 0.0331
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0154 0.0169
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0339 0.0321
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0154 0.0197
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0524 0.387
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0068 0.0075
Entamoeba histolytica hypothetical protein 0.0037 0.0269 0.02
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0894 1 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0154 0.0169
Mycobacterium tuberculosis Conserved protein 0.0037 0.0265 0.0412
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0433 0.0555
Loa Loa (eye worm) hypothetical protein 0.0051 0.043 0.0926
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0271 0.0348
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0265 0.0247
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0154 0.0169
Schistosoma mansoni intermediate filament proteins 0.0027 0.016 0.0203
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0154 0.0326
Schistosoma mansoni chromobox protein 0.0071 0.066 0.0847
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0154 0.0169
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0685 0.0879
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0154 0.0169
Mycobacterium leprae Conserved hypothetical protein 0.0287 0.3112 0.6298
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0154 0.0197
Brugia malayi PHD-finger family protein 0.0059 0.0524 0.1125
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0068 0.0075
Echinococcus granulosus orexin receptor type 2 0.0027 0.0154 0.0197
Brugia malayi Heterochromatin protein 1 0.0071 0.066 0.1419
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0027 0.0154 0.0195
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0154 0.0197
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0068 0.0075
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Schistosoma mansoni biogenic amine receptor 0.0027 0.0154 0.0195
Schistosoma mansoni hypothetical protein 0.0016 0.0034 0.0041
Brugia malayi hypothetical protein 0.0027 0.0154 0.0326
Brugia malayi jmjC domain containing protein 0.0073 0.0685 0.1472
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0339 0.0265
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0071 0.0135
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0002 0.0002
Mycobacterium tuberculosis Conserved hypothetical protein 0.0287 0.3112 0.6421
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0271 0.0253
Brugia malayi neuropeptide F receptor 0.0027 0.0154 0.0326
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0034 0.0068
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0154 0.0195
Schistosoma mansoni growth hormone secretagogue receptor 0.0027 0.0154 0.0195
Schistosoma mansoni inositol monophosphatase 0.0037 0.0271 0.0345
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0198 0.0422
Echinococcus granulosus neuropeptide receptor 0.0027 0.0154 0.0197
Schistosoma mansoni opsin-like receptor 0.0027 0.0154 0.0195
Giardia lamblia Fructose-bisphosphate aldolase 0.0894 1 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0894 1 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0265 0.0412
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0194 0.2057 0.2646
Onchocerca volvulus 0.0029 0.0184 0.0044
Loa Loa (eye worm) hypothetical protein 0.0059 0.0524 0.1129
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0154 0.0197
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0265 0.0412
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0154 0.0197
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0034 0.0044
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0154 0.0169
Mycobacterium tuberculosis Conserved protein 0.0287 0.3112 0.6421
Brugia malayi Bromodomain containing protein 0.0059 0.0524 0.1125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0154 0.0169
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0154 0.0197
Echinococcus multilocularis serotonin receptor 0.0027 0.0154 0.0169
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0269 0.0346
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0265 0.0412
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0265 0.0292
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.007 0.0146
Brugia malayi Inositol-1 0.0037 0.0271 0.0579
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0812 0.9073 1
Schistosoma mansoni neuropeptide receptor 0.0027 0.0154 0.0195
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0154 0.0195
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0269 0.0343
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0154 0.0197
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0154 0.0169
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0544 0.0697
Toxoplasma gondii exonuclease III APE 0.0019 0.007 0.0016
Echinococcus granulosus lamin dm0 0.0027 0.016 0.0206
Schistosoma mansoni hypothetical protein 0.0059 0.0524 0.0672
Schistosoma mansoni amine GPCR 0.0027 0.0154 0.0195
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0154 0.0169
Brugia malayi Melatonin receptor type 1A 0.0027 0.0154 0.0326
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0002 0.0003
Brugia malayi PHD-finger family protein 0.0021 0.009 0.0189
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0544 0.4037
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Loa Loa (eye worm) hypothetical protein 0.004 0.0304 0.0656
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0154 0.0169
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0154 0.0197
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0265 0.0412
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.1247 0.2484
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0087 0.0112
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0154 0.0197
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0154 0.0197
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0265 0.0338
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0154 0.0195
Onchocerca volvulus 0.0643 0.7152 1
Mycobacterium tuberculosis Conserved protein 0.0037 0.0265 0.0412
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Brugia malayi Thioredoxin family protein 0.0287 0.3112 0.6703
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0154 0.0169
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0422 0.4642 1
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.0685 0.0881
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus g protein coupled receptor 0.0027 0.0154 0.0197
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0265 0.973
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.1247 0.2484
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0184 0.0397
Echinococcus granulosus allatostatin A receptor 0.0027 0.0154 0.0197
Schistosoma mansoni cpg binding protein 0.0031 0.0203 0.0259
Loa Loa (eye worm) hypothetical protein 0.0021 0.009 0.0193
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0154 0.0169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0154 0.0195
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0154 0.0197
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0271 0.0298
Schistosoma mansoni chromobox protein 0.0071 0.066 0.0847
Echinococcus multilocularis somatostatin receptor 0.0027 0.0154 0.0169
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0271 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0437 0.4809 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0154 0.0169
Loa Loa (eye worm) hypothetical protein 0.0102 0.1006 0.2166
Mycobacterium tuberculosis Hypothetical protein 0.0287 0.3112 0.6421
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0154 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0024 0.0006
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0436 0.0934
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0034 0.0044
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.1247 0.1375
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0894 1 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0073 0.0677 0.0868
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.1247 0.2484
Echinococcus multilocularis serotonin receptor 0.0027 0.0154 0.0169
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0154 0.0195
Brugia malayi jmjC domain containing protein 0.0194 0.2057 0.4429
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0027 0.0154 0.0195
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0265 0.0247
Echinococcus multilocularis chromobox protein 1 0.0071 0.066 0.0728
Echinococcus granulosus dnaJ subfamily B 0.0419 0.4605 0.5922
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.007 0.0041
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0154 0.0169
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0894 1 1
Echinococcus granulosus neuropeptide receptor 0.0027 0.0154 0.0197
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0068 0.0085
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0027 0.0154 0.0195
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0437 0.4809 1
Echinococcus granulosus neuropeptide s receptor 0.0027 0.0154 0.0197
Giardia lamblia PHD finger protein 15 0.0059 0.0524 0.0458
Leishmania major hypothetical protein, conserved 0.0037 0.0265 0.1671
Onchocerca volvulus 0.0052 0.0436 0.0403
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0059 0.0041
Mycobacterium ulcerans hypothetical protein 0.0037 0.0265 0.0412
Toxoplasma gondii ABC1 family protein 0.0037 0.0265 0.1671
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0265 0.973
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0894 1 1
Echinococcus granulosus somatostatin receptor 0.0027 0.0154 0.0197
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0154 0.0169
Mycobacterium leprae Probable lipase LipE 0.0037 0.0265 0.0084
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0265 0.0412
Mycobacterium tuberculosis Conserved hypothetical protein 0.0287 0.3112 0.6421
Brugia malayi hypothetical protein 0.0253 0.2719 0.5856
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.0091 0.0506
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0027 0.0154 0.0195
Trichomonas vaginalis chromobox protein, putative 0.0071 0.066 0.0643
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0027 0.0154 0.0195
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.007 0.0052
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0154 0.0197
Onchocerca volvulus 0.0027 0.016 0.001
Schistosoma mansoni biogenic amine receptor 0.0027 0.0154 0.0195
Brugia malayi RE15519p 0.0027 0.0154 0.0326
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0685 0.1476
Brugia malayi SET domain containing protein 0.0015 0.0016 0.0029
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0068 0.0087
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Brugia malayi jmjC domain containing protein 0.0019 0.0068 0.0142
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0059 0.0041
Trichomonas vaginalis esterase, putative 0.0037 0.0265 0.0247
Echinococcus granulosus fmrfamide receptor 0.0027 0.0154 0.0197
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0433 0.0478
Brugia malayi G-protein coupled receptor 0.0027 0.0154 0.0326
Schistosoma mansoni hypothetical protein 0.0698 0.7776 1
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0265 0.414
Echinococcus granulosus peregrin 0.0059 0.0524 0.0674
Mycobacterium tuberculosis Conserved protein 0.0037 0.0265 0.0412
Echinococcus granulosus neuropeptide receptor A26 0.0027 0.0154 0.0197
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0894 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0154 0.0169
Echinococcus granulosus lamin 0.0027 0.016 0.0206
Schistosoma mansoni ap endonuclease 0.0019 0.007 0.0087
Brugia malayi jmjC domain containing protein 0.0019 0.0068 0.0142
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0027 0.0154 0.0195
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0154 0.0326
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0265 0.0341
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus g protein coupled receptor 0.0027 0.0154 0.0197
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0154 0.0195
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus g protein coupled receptor 0.0027 0.0154 0.0197
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0068 0.0146
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.007 0.0077
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Schistosoma mansoni hypothetical protein 0.0287 0.3112 0.4001
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0154 0.0197
Echinococcus granulosus hypothetical protein 0.0027 0.0154 0.0197
Schistosoma mansoni hypothetical protein 0.0016 0.0034 0.0041
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0894 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0154 0.0197
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0154 0.0331
Mycobacterium ulcerans hypothetical protein 0.0287 0.3112 0.6421
Schistosoma mansoni inositol monophosphatase 0.0037 0.0271 0.0345
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.066 0.1423
Echinococcus granulosus geminin 0.0698 0.7776 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0034 0.0073
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0437 0.4809 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0059 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0154 0.0195
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0154 0.0169
Schistosoma mansoni amine GPCR 0.0027 0.0154 0.0195
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0269 0.0296
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0154 0.0197
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0524 0.1129
Brugia malayi hypothetical protein 0.0037 0.0269 0.0575
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0059 0.0041
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.2499 0.5127
Echinococcus multilocularis Transglutaminase 0.0287 0.3112 0.3431
Brugia malayi jmjC domain containing protein 0.0019 0.0068 0.0142
Onchocerca volvulus 0.0037 0.0265 0.0159
Trichomonas vaginalis chromobox protein, putative 0.0071 0.066 0.0643
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0172 0.0154
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.1247 0.1602
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0433 0.0934
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0068 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0154 0.0169
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0068 0.0087
Schistosoma mansoni myosin xvIII 0.0027 0.0154 0.0195
Schistosoma mansoni jumonji domain containing protein 0.0154 0.1604 0.206
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0154 0.0331
Brugia malayi intermediate filament protein 0.0027 0.016 0.0341
Echinococcus granulosus survival motor neuron protein 1 0.0253 0.2719 0.3497
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Giardia lamblia Transglutaminase/protease, putative 0.0287 0.3112 0.3064
Echinococcus multilocularis chromobox protein 1 0.0071 0.066 0.0728
Echinococcus multilocularis geminin 0.0698 0.7776 0.8571
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0154 0.0169
Mycobacterium tuberculosis Long conserved protein 0.0287 0.3112 0.6421
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0154 0.0169
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0154 0.0331
Loa Loa (eye worm) hypothetical protein 0.0037 0.0265 0.0571
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0154 0.0169
Brugia malayi hypothetical protein 0.0027 0.0154 0.0326
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0508 0.3733
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.1247 1
Schistosoma mansoni adenoreceptor 0.0027 0.0154 0.0195
Schistosoma mansoni amine GPCR 0.0027 0.0154 0.0195
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Loa Loa (eye worm) hypothetical protein 0.0037 0.0265 0.0571
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0154 0.0169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus multilocularis dnaJ subfamily B 0.0419 0.4605 0.5076
Schistosoma mansoni biogenic amine receptor 0.0027 0.0154 0.0195
Schistosoma mansoni neuropeptide receptor 0.0027 0.0154 0.0195
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0433 0.0557
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.043 0.0922
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.043 0.0926
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0271 0.0253
Loa Loa (eye worm) hypothetical protein 0.0037 0.0265 0.0571
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.007 0.0092
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0154 0.0195
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0154 0.0169
Brugia malayi beta-lactamase family protein 0.0037 0.0265 0.0567
Schistosoma mansoni lamin 0.0027 0.016 0.0203
Echinococcus multilocularis GPCR, family 2 0.0016 0.0034 0.0037
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0265 0.0412
Echinococcus multilocularis lysine specific demethylase 5A 0.0072 0.0666 0.0734
Brugia malayi G-protein coupled receptor 0.0027 0.0154 0.0326
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0265 0.973
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0154 0.0169
Schistosoma mansoni neuropeptide receptor 0.0027 0.0154 0.0195
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0265 0.0571
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0154 0.0195
Entamoeba histolytica hypothetical protein 0.0037 0.0269 0.02
Schistosoma mansoni hypothetical protein 0.0035 0.0247 0.0315
Schistosoma mansoni hypothetical protein 0.0019 0.0071 0.0088
Entamoeba histolytica hypothetical protein 0.0037 0.0269 0.02
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0059 0.0041
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0154 0.0169
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0524 0.387
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Schistosoma mansoni alpha-1 adrenergic receptor 0.0027 0.0154 0.0195
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.007 0.0092
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.043 0.0922
Onchocerca volvulus 0.0031 0.0206 0.0076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0154 0.0169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0154 0.0197
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.007 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0154 0.0169
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0154 0.0197
Brugia malayi larval opioid receptor 0.0027 0.0154 0.0326
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0894 1 1
Echinococcus granulosus serotonin receptor 0.0027 0.0154 0.0197
Brugia malayi neuropeptide F receptor 0.0027 0.0154 0.0326
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0271 1
Brugia malayi ORL1-like opioid receptor 0.0027 0.0154 0.0326
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Loa Loa (eye worm) hypothetical protein 0.0253 0.2719 0.5858
Mycobacterium ulcerans lipase LipD 0.0037 0.0265 0.0412
Schistosoma mansoni hypothetical protein 0.0016 0.0034 0.0041
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0154 0.0331
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0271 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus phd:f box containing protein 0.0019 0.0068 0.0087
Brugia malayi hypothetical protein 0.0027 0.0154 0.0326
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0154 0.0197
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0154 0.0169
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0034 0.0068
Loa Loa (eye worm) hypothetical protein 0.0031 0.0206 0.0445
Loa Loa (eye worm) beta-lactamase 0.0037 0.0265 0.0571
Echinococcus granulosus Transglutaminase 0.0287 0.3112 0.4002
Brugia malayi Dopamine receptor 0.0027 0.0154 0.0326
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0265 0.0247
Loa Loa (eye worm) hypothetical protein 0.0027 0.016 0.0345
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0271 0.0424
Schistosoma mansoni opsin-like receptor 0.0027 0.0154 0.0195
Loa Loa (eye worm) hypothetical protein 0.0037 0.0265 0.0571
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0524 0.0672
Echinococcus granulosus jumonji domain containing protein 0.0083 0.0788 0.1014
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.016 0.0341
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0059 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0154 0.0197
Schistosoma mansoni opsin-like receptor 0.0027 0.0154 0.0195
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0154 0.0197
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0154 0.0169
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0154 0.0195
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0154 0.0195
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.007 0.009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0155 0.0333
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0087 0.0096
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0071 0.0135
Mycobacterium leprae Conserved hypothetical protein 0.0287 0.3112 0.6298
Loa Loa (eye worm) hypothetical protein 0.0027 0.0154 0.0331
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0154 0.0197
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0073
Loa Loa (eye worm) hypothetical protein 0.0037 0.0265 0.0571
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0154 0.0197
Brugia malayi beta-lactamase 0.0037 0.0265 0.0567
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0154 0.0197
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0154 0.0195

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 2.3 nM Binding affinity for dopamine D2 receptor ChEMBL. 15501032
Ki (binding) = 3.2 nM Binding affinity for dopamine D3 receptor ChEMBL. 15501032
Ki (binding) = 19.1 nM Binding affinity for dopamine D4 receptor ChEMBL. 15501032
Ratio (binding) = 0.12 Binding affinity for dopamine D2 receptor to that of dopamine D4 receptor ChEMBL. 15501032

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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