TDR Targets

Basic information

Technical information

TDR Targets ID: 342567
Name: 2-amino-7-methoxy-4-(3-nitrophenyl)-4H-chrome ne-3-carbonitrile
MW: 323.303 | Formula: C17H13N3O4
H donors: 1 H acceptors: 3 LogP: 3.09 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc2c(c1)OC(=C(C2c1cccc(c1)[N+](=O)[O-])C#N)N
InChi: 1S/C17H13N3O4/c1-23-12-5-6-13-15(8-12)24-17(19)14(9-18)16(13)10-3-2-4-11(7-10)20(21)22/h2-8,16H,19H2,1H3
InChiKey: XZVMSUCGEVBBHO-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

2-amino-7-methoxy-4-(3-nitrophenyl)-4H-1-benzopyran-3-carbonitrile
2-azanyl-7-methoxy-4-(3-nitrophenyl)-4H-chromene-3-carbonitrile

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0205	0.457	0.457
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0211	0.0211
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Echinococcus granulosus	geminin	0.0167	0.3625	0.3625
Toxoplasma gondii	5'-nucleotidase, C-terminal domain-containing protein	0.0268	0.6145	1
Trypanosoma cruzi	tyrosine specific protein phosphatase, putative	0.0021	0.0001	0.0235
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Brugia malayi	hypothetical protein	0.0021	0.0001	0.0001
Schistosoma mansoni	pcd6 interacting protein-related	0.0021	0.0001	0.0001
Echinococcus multilocularis		0.0021	0.0001	0.0001
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Trypanosoma cruzi	tyrosine specific protein phosphatase, putative	0.0021	0.0001	0.0235
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0021	0.0001	0.0001
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0021	0.0001	0.0001
Loa Loa (eye worm)	glutaminase	0.0269	0.6166	0.6166
Brugia malayi	Protein-tyrosine phosphatase 1	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0029	0.0211	0.0211
Brugia malayi	hypothetical protein	0.0021	0.0001	0.0001
Entamoeba histolytica	Pten 3-phosphoinositide phosphatase, putative	0.0021	0.0001	0.0002
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0021	0.0001	0.0001
Giardia lamblia	Protein tyrosine phosphatase	0.0021	0.0001	0.0006
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0021	0.0001	0.0001
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0021	0.0001	0.0001
Echinococcus granulosus	protein tyrosine phosphatase n9	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Treponema pallidum	5'-nucleotidase (ushA)	0.0268	0.6145	0.5
Plasmodium vivax	SET domain protein, putative	0.0029	0.0211	1
Brugia malayi	protein-tyrosine phosphatase Lar-like precursor, putative	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Trypanosoma cruzi	tyrosine specific protein phosphatase, putative	0.0021	0.0001	0.0235
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Toxoplasma gondii	HEAT repeat-containing protein	0.0028	0.0186	0.0303
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0287	0.6626	1
Trichomonas vaginalis	glutaminase, putative	0.0269	0.6166	1
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Brugia malayi	Importin beta-1 subunit	0.0028	0.0186	0.0186
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0029	0.0211	0.0211
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0021	0.0001	0.0001
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0021	0.0001	0.0001
Echinococcus multilocularis	receptor type tyrosine protein phosphatase H	0.0021	0.0001	0.0001
Echinococcus multilocularis	geminin	0.0167	0.3625	0.3625
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Echinococcus granulosus	Receptor type tyrosine protein phosphatase O	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Onchocerca volvulus		0.0233	0.5273	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0029	0.0211	0.0211
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Leishmania major	tyrosine specific protein phosphatase, putative	0.0021	0.0001	0.0235
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Leishmania major	importin beta-1 subunit, putative	0.0023	0.0053	1
Schistosoma mansoni	protein tyrosine phosphatase	0.0021	0.0001	0.0001
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Echinococcus granulosus	Receptor type tyrosine protein phosphatase O	0.0021	0.0001	0.0001
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Schistosoma mansoni	receptor protein tyrosine phosphatase	0.0287	0.6626	0.6626
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0186	0.0186
Brugia malayi	Dual specificity protein phosphatase CDC14B	0.0021	0.0001	0.0001
Schistosoma mansoni	protein tyrosine phosphatase non-receptor type nt1	0.0423	1	1
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0423	1	1
Trypanosoma brucei	importin beta-1 subunit, putative	0.0028	0.0186	1
Schistosoma mansoni	hypothetical protein	0.0303	0.7008	0.7008
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Echinococcus multilocularis	snurportin 1	0.0303	0.7008	0.7008
Echinococcus granulosus	histone lysine methyltransferase setb	0.0029	0.0211	0.0211
Trichomonas vaginalis	pten, drome, putative	0.0021	0.0001	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0029	0.0211	0.0343
Schistosoma mansoni	hypothetical protein	0.0167	0.3625	0.3625
Echinococcus multilocularis	hypothetical protein	0.0021	0.0001	0.0001
Schistosoma mansoni	23-cyclic-nucleotide 2-phosphodiesterase	0.0268	0.6145	0.6145
Entamoeba histolytica	hypothetical protein	0.0023	0.0053	0.008
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0021	0.0001	0.0001
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Brugia malayi	Pre-SET motif family protein	0.0205	0.457	0.457
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0021	0.0001	0.0001
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Schistosoma mansoni	23-cyclic-nucleotide 2-phosphodiesterase	0.0267	0.6126	0.6126
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Echinococcus granulosus	importin subunit beta 1	0.0028	0.0186	0.0186
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0029	0.0211	0.0211
Brugia malayi	RNA, U transporter 1	0.0081	0.1486	0.1486
Schistosoma mansoni	receptor protein tyrosine phosphatase n (ia2)	0.0021	0.0001	0.0001
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0423	1	1
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0023	0.0053	0.0086
Brugia malayi	glutaminase DH11.1	0.0269	0.6166	0.6166
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Brugia malayi	hypothetical protein	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Toxoplasma gondii	5'-nucleotidase, C-terminal domain-containing protein	0.011	0.2224	0.362
Loa Loa (eye worm)	protein-tyrosine-phosphatase	0.0021	0.0001	0.0001
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0303	0.7008	0.7008
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0021	0.0001	0.0001
Schistosoma mansoni	protein tyrosine phosphatase	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0021	0.0001	0.0001
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Trypanosoma brucei	protein tyrosine phosphatase 1	0.0021	0.0001	0.0067
Brugia malayi	hypothetical protein	0.0021	0.0001	0.0001
Schistosoma mansoni	receptor protein tyrosine phosphatase r (pcptp1)	0.0021	0.0001	0.0001
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0021	0.0001	0.0001
Schistosoma mansoni	protein-tyrosine phosphatase non-receptor type nt5	0.0021	0.0001	0.0001
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0021	0.0001	0.0001
Schistosoma mansoni	hypothetical protein	0.0167	0.3625	0.3625
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Leishmania major	protein-tyrosine phosphatase 1-like protein	0.0021	0.0001	0.0235
Schistosoma mansoni	rgs-gaip interacting protein gipc	0.0021	0.0001	0.0001
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase 1	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Schistosoma mansoni	protein-tyrosine phosphatase n9	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Trichomonas vaginalis	importin beta-1, putative	0.0023	0.0053	0.0086
Giardia lamblia	Hypothetical protein	0.011	0.2205	1
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0287	0.6626	0.6626
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Trypanosoma brucei	importin beta-1 subunit, putative	0.0028	0.0186	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0029	0.0211	0.0211
Echinococcus granulosus	snurportin 1	0.0303	0.7008	0.7008
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0029	0.0211	0.0211
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Schistosoma mansoni	non-receptor protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Plasmodium vivax	importin-beta 2, putative	0.0028	0.0186	0.8822
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	dual specificity protein phosphatase CDC14B	0.0021	0.0001	0.0001
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Mycobacterium ulcerans	glutaminase	0.0269	0.6166	0.5
Echinococcus multilocularis	importin subunit beta 1	0.0028	0.0186	0.0186
Echinococcus granulosus	receptor type tyrosine protein phosphatase zeta	0.0287	0.6626	0.6626
Onchocerca volvulus		0.0029	0.0211	0.0398
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein tyrosine phosphatase	0.0021	0.0001	0.0001
Brugia malayi	Pre-SET motif family protein	0.0029	0.0211	0.0211
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0021	0.0001	0.0001
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0021	0.0001	0.0001
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0028	0.0184	0.0184
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0423	1	1
Brugia malayi	Protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Trichomonas vaginalis	set domain proteins, putative	0.0233	0.5273	0.8553
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0021	0.0001	0.0001
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0023	0.0053	0.0086
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0021	0.0001	0.0001
Echinococcus granulosus	receptor type tyrosine protein phosphatase zeta	0.0021	0.0001	0.0001
Brugia malayi	hypothetical protein	0.0021	0.0001	0.0001
Schistosoma mansoni	protein tyrosine phosphatase	0.0021	0.0001	0.0001
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0021	0.0001	0.0001
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0021	0.0001	0.0001
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Echinococcus multilocularis	protein tyrosine phosphatase n9	0.0021	0.0001	0.0001
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0021	0.0001	0.0002
Loa Loa (eye worm)	glutaminase 2	0.0269	0.6166	0.6166
Schistosoma mansoni	receptor protein tyrosine phosphatase n (ia2)	0.0021	0.0001	0.0001
Plasmodium falciparum	importin beta, putative	0.0028	0.0186	1
Trypanosoma cruzi	importin beta-1 subunit, putative	0.0023	0.0053	1
Schistosoma mansoni	glutaminase	0.0269	0.6166	0.6166
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0021	0.0001	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0001	0.0001
Schistosoma mansoni	importin beta-1	0.0028	0.0186	0.0186

Activities

Activity type	Activity value	Assay description	Source	Reference
EC50 (functional)	= 1.051	Induction of apoptosis in human T47D cells	ChEMBL.	17870538
EC50 (functional)	= 0.089 uM	Effective concentration against human breast cancer T47D cell line apoptosis inducing activity was measured by using cell and caspase-based HTS assay	ChEMBL.	16143530
EC50 (functional)	= 0.089 uM	Effective concentration against human breast cancer T47D cell line apoptosis inducing activity was measured by using cell and caspase-based HTS assay	ChEMBL.	16143530
EC50 (functional)	= 0.17 uM	Effective concentration against human non-small cell lung cancer H1299 cells inducing apoptosis, activity was measured by cell and caspase-based HTS assay	ChEMBL.	16143530
EC50 (functional)	= 0.17 uM	Effective concentration against human non-small cell lung cancer H1299 cells inducing apoptosis, activity was measured by cell and caspase-based HTS assay	ChEMBL.	16143530
Log (1/C) (functional)	= 7.05	Induction of apoptosis in human HL60 B cells	ChEMBL.	17658263
log(1/EC50) (functional)	= 1.051	Induction of apoptosis in human T47D cells	ChEMBL.	17870538

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Homo sapiens	ChEMBL23	16143530

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

PubChem: 9966982

Bibliographic References

3 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 342567