Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Adenosine A1 receptor | Starlite/ChEMBL | References |
Rattus norvegicus | Adenosine A2 receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glycoprotein 3 alpha L fucosyltransferase | 0.0174 | 0 | 0.5 |
Echinococcus multilocularis | glycoprotein 3 alpha L fucosyltransferase | 0.0174 | 0 | 0.5 |
Echinococcus multilocularis | glycoprotein 3 alpha L fucosyltransferase | 0.0174 | 0 | 0.5 |
Echinococcus multilocularis | glycoprotein 3 alpha L fucosyltransferase | 0.0174 | 0 | 0.5 |
Echinococcus granulosus | glycoprotein 3 alpha L fucosyltransferase | 0.0174 | 0 | 0.5 |
Echinococcus granulosus | alpha13fucosyltransferase | 0.0174 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.041 | 1 | 1 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.041 | 1 | 1 |
Echinococcus granulosus | glycoprotein 3 alpha L fucosyltransferase | 0.0174 | 0 | 0.5 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.041 | 1 | 1 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.041 | 1 | 1 |
Echinococcus multilocularis | glycoprotein 3 alpha L fucosyltransferase | 0.0174 | 0 | 0.5 |
Brugia malayi | alpha1,3-fucosyltransferase homologue | 0.041 | 1 | 0.5 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.041 | 1 | 1 |
Onchocerca volvulus | Alpha 1,3 fucosyltransferase homolog | 0.0174 | 0 | 0.5 |
Echinococcus granulosus | glycoprotein 3 alpha L fucosyltransferase | 0.0174 | 0 | 0.5 |
Schistosoma mansoni | alpha(13)fucosyltransferase | 0.041 | 1 | 1 |
Loa Loa (eye worm) | fucosyl transferase | 0.041 | 1 | 1 |
Echinococcus multilocularis | alpha(13)fucosyltransferase | 0.0174 | 0 | 0.5 |
Echinococcus multilocularis | alpha(13)fucosyltransferase | 0.0174 | 0 | 0.5 |
Echinococcus granulosus | glycoprotein 3 alpha L fucosyltransferase | 0.0174 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 56.2 nM | Binding affinity against adenosine A2 receptor in rat brain using [3H]- CGS 21680 as radioligand | ChEMBL. | 8496902 |
Ki (binding) | = 56.2 nM | Binding affinity against adenosine A2 receptor in rat brain using [3H]- CGS 21680 as radioligand | ChEMBL. | 8496902 |
Ki (binding) | = 272 nM | Affinity against Adenosine A1 receptor in rat brain using [3H]- PIA as radioligand | ChEMBL. | 8496902 |
Ki (binding) | = 272 nM | Affinity against Adenosine A1 receptor in rat brain using [3H]- PIA as radioligand | ChEMBL. | 8496902 |
Ratio (binding) | = 4.8 | Ratio between Ki of adenosine A1 receptor to that of adenosine A2 receptor | ChEMBL. | 8496902 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.