TDR Targets

Basic information

Technical information

TDR Targets ID: 35666
Name: 2-[5-(4-cyanobenzoyl)-1-methylpyrrol-2-yl]-N- [2,4-dichloro-3-[(2-methylquinolin-8-yl)oxyme thyl]phenyl]-N-methylacetamide
MW: 597.491 | Formula: C33H26Cl2N4O3
H donors: 0 H acceptors: 4 LogP: 6.44 Rotable bonds: 9
Rule of 5 violations (Lipinski): 2
SMILES: N#Cc1ccc(cc1)C(=O)c1ccc(n1C)CC(=O)N(c1ccc(c(c1Cl)COc1cccc2c1nc(C)cc2)Cl)C
InChi: 1S/C33H26Cl2N4O3/c1-20-7-10-22-5-4-6-29(32(22)37-20)42-19-25-26(34)14-16-27(31(25)35)39(3)30(40)17-24-13-15-28(38(24)2)33(41)23-11-8-21(18-36)9-12-23/h4-16H,17,19H2,1-3H3
InChiKey: XDSJSAQKNVFGCS-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

2-[5-(4-cyanobenzoyl)-1-methyl-pyrrol-2-yl]-N-[2,4-dichloro-3-[(2-methyl-8-quinolyl)oxymethyl]phenyl]-N-methyl-acetamide
2-[5-[(4-cyanophenyl)-oxomethyl]-1-methyl-2-pyrrolyl]-N-[2,4-dichloro-3-[(2-methyl-8-quinolyl)oxymethyl]phenyl]-N-methylacetamide
2-[5-(4-cyanophenyl)carbonyl-1-methyl-pyrrol-2-yl]-N-[2,4-dichloro-3-[(2-methylquinolin-8-yl)oxymethyl]phenyl]-N-methyl-ethanamide

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	bradykinin receptor B2	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	bradykinin receptor B2	391 aa	354 aa	19.2 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	neuropeptide Y receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	serotonin transporter b	0.0147	0.0488	0.0488
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0087	0.0241	0.0241
Echinococcus multilocularis	cathepsin L	0.0048	0.008	0.008
Brugia malayi	Serotonin receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Brugia malayi	G protein-coupled receptor F59B2.13	0.0087	0.0241	0.0241
Trypanosoma cruzi	cysteine peptidase, putative	0.0082	0.0218	0.0257
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	ctsf protein	0.0082	0.0218	0.0218
Echinococcus multilocularis	serotonin receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	fibroinase	0.0082	0.0218	0.0218
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0048	0.008	0.0074
Schistosoma mansoni	hypothetical protein	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0048	0.0078	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0087	0.0241	0.0241
Schistosoma mansoni	hypothetical protein	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	cathepsin b	0.0438	0.1686	0.1686
Schistosoma mansoni	cellular tumor antigen P53	0.0048	0.0078	0.0078
Onchocerca volvulus		0.0035	0.0025	0.0025
Echinococcus granulosus	tm gpcr rhodopsin	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus granulosus	neuropeptide s receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus granulosus	neuropeptide receptor A26	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0087	0.0241	0.0241
Brugia malayi	Dopamine receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0147	0.0488	0.0488
Brugia malayi	G-protein coupled receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Brugia malayi	Cathepsin L-like precursor	0.0082	0.0218	0.0218
Loa Loa (eye worm)	TYRA-2 protein	0.0087	0.0241	0.0241
Echinococcus granulosus	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Onchocerca volvulus		0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Onchocerca volvulus		0.0087	0.0241	0.0241
Trichomonas vaginalis	set domain proteins, putative	0.0229	0.0826	1
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0048	0.008	0.0695
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Brugia malayi	Dopamine receptor protein 2	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0082	0.0218	0.0218
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0082	0.0218	0.0218
Schistosoma mansoni	amine GPCR	0.0087	0.0241	0.0241
Onchocerca volvulus	Vesicular acetylcholine transporter homolog	0.2455	1	1
Schistosoma mansoni	hypothetical protein	0.0033	0.0017	0.0017
Mycobacterium leprae	conserved hypothetical protein	0.0035	0.0025	0.5
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0082	0.0218	0.2419
Echinococcus granulosus	beta LACTamase domain containing family member	0.0035	0.0025	0.0025
Brugia malayi	follicle stimulating hormone receptor	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0082	0.0218	0.0218
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0124	0.0124
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0082	0.0218	0.2419
Echinococcus granulosus	somatostatin receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0025	0.0025
Echinococcus granulosus	fmrfamide receptor	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0082	0.0218	0.0218
Echinococcus granulosus	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0087	0.0241	0.0241
Echinococcus multilocularis	G protein coupled receptor 139	0.0087	0.0241	0.0241
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	neuropeptide receptor	0.0087	0.0241	0.0241
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0087	0.0241	0.0241
Brugia malayi	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0087	0.0241	0.0241
Brugia malayi	Serotonin receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	amine GPCR	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Leishmania major	cathepsin L-like protease	0.0082	0.0218	0.0257
Onchocerca volvulus		0.0087	0.0241	0.0241
Trypanosoma cruzi	cysteine proteinase, putative	0.0048	0.008	0.0074
Echinococcus granulosus	allatostatin A receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	cathepsin B	0.0153	0.0512	0.0512
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0438	0.1686	0.1686
Echinococcus multilocularis	cathepsin L cysteine protease	0.0082	0.0218	0.0218
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Brugia malayi	Papain family cysteine protease containing protein	0.0048	0.008	0.008
Loa Loa (eye worm)	hypothetical protein	0.0438	0.1686	0.1686
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0048	0.008	0.0074
Brugia malayi	Cathepsin L-like precursor	0.0082	0.0218	0.0218
Trypanosoma cruzi	cysteine peptidase, putative	0.0048	0.008	0.0074
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Trypanosoma cruzi	cysteine proteinase, putative	0.0048	0.008	0.0074
Echinococcus granulosus	vesicular acetylcholine transporter	0.2455	1	1
Schistosoma mansoni	neuropeptide receptor	0.0087	0.0241	0.0241
Brugia malayi	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Entamoeba histolytica	cysteine proteinase, putative	0.0059	0.0124	0.3182
Schistosoma mansoni	neuropeptide F-like receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0087	0.0241	0.0241
Brugia malayi	RE15519p	0.0087	0.0241	0.0241
Echinococcus multilocularis	neuropeptides capa receptor	0.0087	0.0241	0.0241
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0147	0.0488	0.0488
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0124	0.0124
Entamoeba histolytica	cysteine proteinase, putative	0.0082	0.0218	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0082	0.0218	0.2419
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus granulosus	cathepsin b	0.0438	0.1686	0.1686
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0438	0.1686	0.1686
Schistosoma mansoni	myosin xvIII	0.0087	0.0241	0.0241
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Schistosoma mansoni	opsin-like receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0087	0.0241	0.0241
Brugia malayi	G protein-coupled receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	neuropeptide F receptor	0.0087	0.0241	0.0241
Toxoplasma gondii	cathepsin B	0.0153	0.0512	1
Onchocerca volvulus		0.0087	0.0241	0.0241
Mycobacterium ulcerans	esterase/lipase LipP	0.0035	0.0025	0.5
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0048	0.008	0.008
Loa Loa (eye worm)	transcription factor SMAD2	0.0116	0.0357	0.0357
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0153	0.0512	0.0646
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0087	0.0241	0.0241
Leishmania major	cathepsin L-like protease	0.0082	0.0218	0.0257
Echinococcus multilocularis	neuropeptide receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0087	0.0241	0.0241
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0048	0.008	0.008
Echinococcus multilocularis	somatostatin receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	neuropeptides capa receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0048	0.008	0.008
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0035	0.0025	0.0025
Onchocerca volvulus		0.0059	0.0124	0.0124
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0035	0.0025	0.0025
Echinococcus multilocularis	sex peptide receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	serotonin transporter	0.0147	0.0488	0.0488
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Echinococcus granulosus	neuropeptide receptor	0.0087	0.0241	0.0241
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0048	0.008	0.0074
Leishmania major	cysteine peptidase A (CPA)	0.0082	0.0218	0.0257
Onchocerca volvulus		0.0147	0.0488	0.0488
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	g protein coupled receptor	0.0087	0.0241	0.0241
Leishmania major	cathepsin L-like protease	0.0082	0.0218	0.0257
Onchocerca volvulus		0.0087	0.0241	0.0241
Schistosoma mansoni	amine GPCR	0.0087	0.0241	0.0241
Trypanosoma cruzi	cysteine peptidase, putative	0.0082	0.0218	0.0257
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0082	0.0218	1
Mycobacterium ulcerans	hypothetical protein	0.0035	0.0025	0.5
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0082	0.0218	0.2419
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0153	0.0512	0.0512
Plasmodium vivax	vivapain-2	0.0082	0.0218	1
Leishmania major	cathepsin L-like protease	0.0082	0.0218	0.0257
Echinococcus granulosus	neuropeptide Y receptor	0.0087	0.0241	0.0241
Brugia malayi	Cathepsin L-like precursor	0.0082	0.0218	0.0218
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0082	0.0218	0.0218
Brugia malayi	Cathepsin L-like precursor	0.0059	0.0124	0.0124
Echinococcus multilocularis	neuropeptide receptor A26	0.0087	0.0241	0.0241
Schistosoma mansoni	hypothetical protein	0.0087	0.0241	0.0241
Leishmania major	cathepsin L-like protease	0.0082	0.0218	0.0257
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Brugia malayi	G-protein coupled receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	sodium/chloride dependent transporter	0.0147	0.0488	0.0488
Trypanosoma cruzi	cysteine peptidase, putative	0.0082	0.0218	0.0257
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0059	0.0124	0.0124
Brugia malayi	Pre-SET motif family protein	0.0201	0.0711	0.0711
Plasmodium vivax	vivapain-2	0.0082	0.0218	1
Echinococcus granulosus	biogenic amine 5HT receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	g protein coupled receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0035	0.0025	0.0025
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0025	0.0025
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Schistosoma mansoni	vesicular acetylcholine transporter	0.2455	1	1
Echinococcus multilocularis	tumor protein p63	0.0327	0.1228	0.1228
Brugia malayi	GnHR receptor homolog	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Brugia malayi	Cathepsin L-like precursor	0.0082	0.0218	0.0218
Echinococcus multilocularis	serotonin receptor	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Brugia malayi	cathepsin B-like cysteine proteinase	0.0438	0.1686	0.1686
Echinococcus multilocularis	cysteine protease	0.0082	0.0218	0.0218
Giardia lamblia	Cathepsin B precursor	0.0153	0.0512	0.5
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	cathepsin l1	0.0082	0.0218	0.0218
Loa Loa (eye worm)	hypothetical protein	0.1258	0.5066	0.5066
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0025	0.0025
Trypanosoma cruzi	cysteine peptidase, putative	0.0082	0.0218	0.0257
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0087	0.0241	0.0241
Echinococcus multilocularis	allatostatin A receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0087	0.0241	0.0241
Echinococcus multilocularis	cathepsin L cysteine protease	0.0082	0.0218	0.0218
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0082	0.0218	0.0218
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0025	0.0025
Echinococcus multilocularis	dro:myosuppressin receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0082	0.0218	0.2419
Schistosoma mansoni	biogenic amine receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	neuropeptide s receptor	0.0087	0.0241	0.0241
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0438	0.1686	0.2202
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0087	0.0241	0.0241
Toxoplasma gondii	ABC1 family protein	0.0035	0.0025	0.048
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus granulosus	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Schistosoma mansoni	neuropeptide receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	neuropeptide F receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0025	0.0025
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0087	0.0241	0.0241
Brugia malayi	cathepsin L-like precursor	0.0059	0.0124	0.0124
Plasmodium vivax	vivapain-1	0.0048	0.008	0.3675
Echinococcus granulosus	biogenic amine 5HT receptor	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0082	0.0218	0.2419
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Loa Loa (eye worm)	melatonin receptor type 1A	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0087	0.0241	0.0241
Echinococcus multilocularis	g protein coupled receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	7tm_1 domain containing protein	0.0087	0.0241	0.0241
Brugia malayi	Melatonin receptor type 1A	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0082	0.0218	0.0218
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0087	0.0241	0.0241
Mycobacterium leprae	Probable lipase LipE	0.0035	0.0025	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0087	0.0241	0.0241
Leishmania major	cathepsin L-like protease	0.0082	0.0218	0.0257
Entamoeba histolytica	cysteine protease, putative	0.0082	0.0218	1
Echinococcus granulosus	serotonin receptor	0.0087	0.0241	0.0241
Brugia malayi	latrophilin 2 splice variant baaae	0.0033	0.0017	0.0017
Echinococcus granulosus	cysteine protease	0.0048	0.008	0.008
Plasmodium vivax	hypothetical protein, conserved	0.0035	0.0025	0.1124
Toxoplasma gondii	cathepsin CPL	0.0082	0.0218	0.4267
Onchocerca volvulus	Cathepsin F homolog	0.0082	0.0218	0.0218
Echinococcus granulosus	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0087	0.0241	0.0241
Trypanosoma cruzi	cysteine protease, putative	0.0048	0.008	0.0074
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Giardia lamblia	Cathepsin B precursor	0.0153	0.0512	0.5
Schistosoma mansoni	cathepsin F (C01 family)	0.0082	0.0218	0.0218
Onchocerca volvulus	Cathepsin L homolog	0.0082	0.0218	0.0218
Onchocerca volvulus		0.0087	0.0241	0.0241
Brugia malayi	beta-lactamase family protein	0.0035	0.0025	0.0025
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0124	0.0124
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.0124	0.1244
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0087	0.0241	0.0241
Schistosoma mansoni	amine GPCR	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Schistosoma mansoni	cathepsin F (C01 family)	0.0059	0.0124	0.0124
Mycobacterium ulcerans	lipase LipD	0.0035	0.0025	0.5
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0082	0.0218	0.0218
Echinococcus granulosus	neuropeptide FF receptor 2	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0488	0.0488
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0035	0.0025	0.0025
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0082	0.0218	0.2419
Trypanosoma cruzi	cruzipain precursor, putative	0.0082	0.0218	0.0257
Echinococcus multilocularis	cysteine protease	0.0082	0.0218	0.0218
Onchocerca volvulus		0.0229	0.0826	0.0826
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Brugia malayi	AKH receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0488	0.0488
Brugia malayi	Papain family cysteine protease containing protein	0.0048	0.008	0.008
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0087	0.0241	0.0241
Brugia malayi	hypothetical protein	0.0087	0.0241	0.0241
Leishmania major	C-8 sterol isomerase-like protein	0.1865	0.7569	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0082	0.0218	0.2419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Schistosoma mansoni	neuropeptide receptor	0.0087	0.0241	0.0241
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Onchocerca volvulus		0.0087	0.0241	0.0241
Echinococcus multilocularis	g-protein coupled receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0087	0.0241	0.0241
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0087	0.0241	0.0241
Echinococcus multilocularis	neuropeptide Y receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	fmrfamide receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0953	0.381	0.381
Echinococcus multilocularis	neuropeptide Y receptor	0.0087	0.0241	0.0241
Trypanosoma brucei	C-8 sterol isomerase, putative	0.1865	0.7569	1
Echinococcus granulosus	cathepsin L	0.0048	0.008	0.008
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0082	0.0218	0.2419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Brugia malayi	hypothetical protein	0.0087	0.0241	0.0241
Brugia malayi	hypothetical protein	0.0087	0.0241	0.0241
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0153	0.0512	0.0646
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Brugia malayi	Cathepsin L-like precursor	0.0082	0.0218	0.0218
Brugia malayi	putative neuropeptide receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0087	0.0241	0.0241
Onchocerca volvulus		0.0087	0.0241	0.0241
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0438	0.1686	0.1686
Echinococcus granulosus	dro:myosuppressin receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0035	0.0025	0.0025
Schistosoma mansoni	histamine h1 receptor	0.0087	0.0241	0.0241
Brugia malayi	MH2 domain containing protein	0.0116	0.0357	0.0357
Echinococcus multilocularis	g protein coupled receptor	0.0087	0.0241	0.0241
Giardia lamblia	Cathepsin B precursor	0.0153	0.0512	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0048	0.008	0.0695
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0087	0.0241	0.0241
Loa Loa (eye worm)	norepinephrine transporter	0.0147	0.0488	0.0488
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.0124	0.1244
Loa Loa (eye worm)	G-protein coupled receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0059	0.0124	0.0132
Loa Loa (eye worm)	vesicular acetylcholine transporter unc-17	0.2455	1	1
Plasmodium vivax	vivapain-3	0.0048	0.008	0.3675
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0048	0.008	0.008
Echinococcus granulosus	tm gpcr rhodopsin	0.0087	0.0241	0.0241
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	beta-lactamase	0.0035	0.0025	0.0025
Schistosoma mansoni	biogenic amine receptor	0.0087	0.0241	0.0241
Brugia malayi	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0488	0.0488
Brugia malayi	hypothetical protein	0.1258	0.5066	0.5066
Brugia malayi	hypothetical protein	0.0087	0.0241	0.0241
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0087	0.0241	0.0241
Mycobacterium ulcerans	beta-lactamase	0.0035	0.0025	0.5
Echinococcus granulosus	cathepsin b	0.0438	0.1686	0.1686
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0087	0.0241	0.0241
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus granulosus	tumor protein p63	0.0327	0.1228	0.1228
Onchocerca volvulus		0.0087	0.0241	0.0241
Echinococcus granulosus	sex peptide receptor	0.0087	0.0241	0.0241
Treponema pallidum	sodium- and chloride- dependent transporter	0.0147	0.0488	0.5
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0082	0.0218	0.0218
Echinococcus granulosus	g protein coupled receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0025	0.0025
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.1865	0.7569	0.7569
Brugia malayi	Papain family cysteine protease containing protein	0.0082	0.0218	0.0218
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0035	0.0025	0.0025
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0438	0.1686	0.1686
Loa Loa (eye worm)	hypothetical protein	0.0082	0.0218	0.0218
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0082	0.0218	0.2419
Brugia malayi	neuropeptide F receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	orexin receptor type 2	0.0087	0.0241	0.0241
Schistosoma mansoni	amine GPCR	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0153	0.0512	0.6081
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0048	0.008	0.008
Echinococcus granulosus	cathepsin l1	0.0059	0.0124	0.0124
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0087	0.0241	0.0241
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	growth hormone secretagogue receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	adenoreceptor	0.0087	0.0241	0.0241
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0087	0.0241	0.0241
Loa Loa (eye worm)	solute carrier family 6 member 4	0.0147	0.0488	0.0488
Entamoeba histolytica	cysteine proteinase, putative	0.0082	0.0218	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Echinococcus granulosus	serotonin transporter	0.0147	0.0488	0.0488
Leishmania major	cathepsin L-like protease	0.0082	0.0218	0.0257
Echinococcus granulosus	neuropeptides capa receptor	0.0087	0.0241	0.0241
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0153	0.0512	0.0646
Brugia malayi	hypothetical protein	0.0087	0.0241	0.0241
Brugia malayi	sulfakinin receptor protein	0.1258	0.5066	0.5066
Onchocerca volvulus	Cathepsin L homolog	0.0082	0.0218	0.0218
Loa Loa (eye worm)	MH2 domain-containing protein	0.0116	0.0357	0.0357
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0087	0.0241	0.0241
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Trypanosoma cruzi	C-8 sterol isomerase, putative	0.1865	0.7569	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0087	0.0241	0.0241
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0087	0.0241	0.0241
Echinococcus granulosus	g protein coupled receptor	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0082	0.0218	0.0218
Brugia malayi	Cathepsin L-like precursor	0.0082	0.0218	0.0218
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0223	0.0798	1
Brugia malayi	putative neuropeptide receptor NPR1	0.0087	0.0241	0.0241
Brugia malayi	ERG2 and Sigma1 receptor like protein	0.1865	0.7569	0.7569
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Brugia malayi	beta-lactamase family protein	0.0035	0.0025	0.0025
Echinococcus multilocularis	fmrfamide receptor	0.0087	0.0241	0.0241
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0035	0.0025	0.0025
Schistosoma mansoni	opsin-like receptor	0.0087	0.0241	0.0241
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0082	0.0218	0.2419
Schistosoma mansoni	hypothetical protein	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0087	0.0241	0.0241
Brugia malayi	Cathepsin L-like precursor	0.0059	0.0124	0.0124
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0048	0.008	0.008
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	orexin receptor type 2	0.0087	0.0241	0.0241
Loa Loa (eye worm)	cysteine protease	0.0082	0.0218	0.0218
Brugia malayi	Dopamine receptor protein 1	0.0087	0.0241	0.0241
Leishmania major	cathepsin L-like protease	0.0082	0.0218	0.0257
Echinococcus granulosus	7TM GPCR rhodopsin	0.0087	0.0241	0.0241
Schistosoma mansoni	cathepsin F (C01 family)	0.0082	0.0218	0.0218
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0035	0.0025	0.5
Echinococcus granulosus	cathepsin L cysteine protease	0.0048	0.008	0.008
Onchocerca volvulus		0.0082	0.0218	0.0218
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0087	0.0241	0.0241
Brugia malayi	hypothetical protein	0.0087	0.0241	0.0241
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0087	0.0241	0.0241
Brugia malayi	larval opioid receptor	0.0087	0.0241	0.0241
Echinococcus granulosus	neuropeptides capa receptor	0.0087	0.0241	0.0241
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0078	0.0078
Schistosoma mansoni	neuropeptide receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	vesicular acetylcholine transporter	0.2455	1	1
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Echinococcus granulosus	tm gpcr rhodopsin	0.0087	0.0241	0.0241
Echinococcus granulosus	G protein coupled receptor 139	0.0087	0.0241	0.0241
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0082	0.0218	0.0218
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0087	0.0241	0.0241
Echinococcus granulosus	g-protein coupled receptor	0.0087	0.0241	0.0241
Echinococcus multilocularis	cathepsin b	0.0438	0.1686	0.1686
Plasmodium vivax	unspecified product	0.0048	0.008	0.3675
Echinococcus multilocularis	neuropeptide receptor	0.0087	0.0241	0.0241
Brugia malayi	ORL1-like opioid receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Schistosoma mansoni	neuropeptide f receptor 76f	0.0087	0.0241	0.0241
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0082	0.0218	1
Loa Loa (eye worm)	G-protein coupled receptor	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0241	0.0241
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0082	0.0218	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0082	0.0218	0.2419
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0082	0.0218	0.0257
Schistosoma mansoni	opsin-like receptor	0.0087	0.0241	0.0241
Brugia malayi	neuropeptide F receptor	0.0087	0.0241	0.0241
Onchocerca volvulus		0.0082	0.0218	0.0218
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0201	0.0711	0.0711
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0087	0.0241	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0048	0.008	0.008
Schistosoma mansoni	biogenic amine receptor	0.0087	0.0241	0.0241
Brugia malayi	beta-lactamase	0.0035	0.0025	0.0025
Schistosoma mansoni	neuropeptide F-like receptor	0.0087	0.0241	0.0241

Activities

Activity type	Activity value	Assay description	Source	Reference
Ki (binding)	= 23 nM	Binding affinity towards human bradykinin receptor B2	ChEMBL.	12657278
Ki (binding)	= 23 nM	Binding affinity towards human bradykinin receptor B2	ChEMBL.	12657278

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

PubChem: 15952860

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 35666