Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Death domain containing protein | 0.0011 | 0.0144 | 0.0144 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0519 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0642 | 0.0642 |
Brugia malayi | nuclear hormone receptor | 0.0037 | 0.167 | 0.167 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0037 | 0.167 | 0.167 |
Onchocerca volvulus | 0.0013 | 0.0251 | 0.1011 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.167 | 0.167 |
Leishmania major | cathepsin L-like protease | 0.0013 | 0.0251 | 0.0863 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0037 | 0.167 | 0.2718 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0114 | 0.6142 | 0.8321 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0013 | 0.0251 | 0.0148 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0066 | 0.3302 | 0.5375 |
Echinococcus granulosus | jun protein | 0.0066 | 0.3302 | 0.5375 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Onchocerca volvulus | 0.0013 | 0.0251 | 0.1011 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.167 | 0.167 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0018 | 0.0519 | 0.0519 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0018 | 0.0519 | 0.0519 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0251 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0136 | 0.7381 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0018 | 0.0519 | 0.0703 |
Schistosoma mansoni | nuclear receptor | 0.0018 | 0.0519 | 0.0703 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0018 | 0.0519 | 0.0845 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0037 | 0.167 | 0.2718 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0037 | 0.167 | 0.167 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0519 | 0.0703 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0018 | 0.0519 | 0.0845 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0013 | 0.0251 | 0.5 |
Brugia malayi | hypothetical protein | 0.002 | 0.0642 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0037 | 0.167 | 0.2108 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0037 | 0.167 | 0.167 |
Schistosoma mansoni | netrin receptor unc5 | 0.0011 | 0.0144 | 0.0195 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0037 | 0.167 | 0.167 |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.005 | 0.005 |
Onchocerca volvulus | 0.0018 | 0.0519 | 0.2089 | |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.005 | 0.005 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0037 | 0.167 | 0.167 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0642 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0037 | 0.167 | 0.2262 |
Echinococcus granulosus | FTZ F1 alpha | 0.0037 | 0.167 | 0.2718 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0018 | 0.0519 | 0.0518 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Plasmodium vivax | vivapain-2 | 0.0013 | 0.0251 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0642 | 0.0642 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0519 | 0.0845 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.002 | 0.0642 | 0.1045 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.005 | 0.2386 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0013 | 0.0251 | 0.0251 |
Brugia malayi | Protein kinase domain containing protein | 0.0011 | 0.0144 | 0.0144 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0251 | 0.0251 |
Echinococcus multilocularis | Ankyrin | 0.0011 | 0.0149 | 0.0008 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0013 | 0.0251 | 0.0251 |
Schistosoma mansoni | jun-related protein | 0.0053 | 0.2588 | 0.3506 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.002 | 0.0642 | 0.0642 |
Echinococcus granulosus | cathepsin l1 | 0.0013 | 0.0251 | 0.0409 |
Onchocerca volvulus | Cathepsin F homolog | 0.0013 | 0.0251 | 0.1011 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0181 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0018 | 0.0519 | 0.0518 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0018 | 0.0519 | 0.0519 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0013 | 0.0251 | 0.0251 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0037 | 0.167 | 0.2108 |
Onchocerca volvulus | 0.0013 | 0.0251 | 0.1011 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.2588 | 0.3506 |
Leishmania major | cysteine peptidase A (CPA) | 0.0013 | 0.0251 | 0.0863 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0018 | 0.0519 | 0.2089 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0037 | 0.167 | 0.2108 |
Brugia malayi | hypothetical protein | 0.002 | 0.0642 | 0.0642 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.001 | 0.005 | 0.005 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0037 | 0.167 | 0.167 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0018 | 0.0519 | 0.0845 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0251 | 0.0251 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Toxoplasma gondii | cathepsin CPL | 0.0013 | 0.0251 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.167 | 0.167 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0066 | 0.3302 | 0.4363 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Brugia malayi | nuclear receptor NHR-67 | 0.0018 | 0.0519 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0037 | 0.167 | 0.167 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0013 | 0.0251 | 0.0148 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0098 | 0.5203 | 0.8471 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2483 | 0.2483 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0037 | 0.167 | 0.2718 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0011 | 0.0144 | 0.000000052255 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0098 | 0.5203 | 0.6991 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0037 | 0.167 | 0.2262 |
Loa Loa (eye worm) | fibroinase | 0.0013 | 0.0251 | 0.0251 |
Onchocerca volvulus | 0.0013 | 0.0251 | 0.1011 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.167 | 0.167 |
Brugia malayi | conserved hypotetical protein | 0.0018 | 0.0519 | 0.0519 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0013 | 0.0251 | 0.034 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0037 | 0.167 | 0.2108 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0251 | 0.0251 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.002 | 0.0642 | 0.087 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0037 | 0.167 | 0.2718 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0011 | 0.0144 | 0.0144 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.167 | 0.167 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0011 | 0.0149 | 0.0202 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.005 | 0.2386 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0018 | 0.0519 | 0.0845 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0011 | 0.0144 | 0.0144 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0037 | 0.167 | 0.167 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0018 | 0.0519 | 0.2089 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0037 | 0.167 | 0.2108 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0136 | 0.7381 | 1 |
Onchocerca volvulus | 0.0013 | 0.0251 | 0.1011 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0037 | 0.167 | 0.167 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0037 | 0.167 | 0.2262 |
Echinococcus granulosus | Ankyrin | 0.0011 | 0.0149 | 0.0243 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0037 | 0.167 | 0.167 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0037 | 0.167 | 0.2108 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0144 | 0.0144 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0013 | 0.0251 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0037 | 0.167 | 0.167 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0037 | 0.167 | 0.167 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0018 | 0.0519 | 0.0519 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Leishmania major | cathepsin L-like protease | 0.005 | 0.2386 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0037 | 0.167 | 0.167 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0013 | 0.0251 | 0.034 |
Schistosoma mansoni | nuclear receptor | 0.0018 | 0.0519 | 0.0703 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0037 | 0.167 | 0.167 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0144 | 0.0195 |
Schistosoma mansoni | zinc finger protein | 0.0018 | 0.0519 | 0.0703 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0037 | 0.167 | 0.2108 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Brugia malayi | tailless protein | 0.0018 | 0.0519 | 0.0519 |
Leishmania major | cathepsin L-like protease | 0.005 | 0.2386 | 1 |
Plasmodium vivax | vivapain-2 | 0.0013 | 0.0251 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0013 | 0.0251 | 0.0148 |
Echinococcus granulosus | death domain containing protein | 0.0011 | 0.0144 | 0.0234 |
Brugia malayi | Uncoordinated protein 44 | 0.0011 | 0.0144 | 0.0144 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0018 | 0.0519 | 0.0845 |
Loa Loa (eye worm) | cysteine protease | 0.0013 | 0.0251 | 0.0251 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0037 | 0.167 | 0.2262 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0013 | 0.0251 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0037 | 0.167 | 0.167 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0018 | 0.0519 | 0.0519 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0037 | 0.167 | 0.6723 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.005 | 0.2386 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0013 | 0.0251 | 0.1011 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0037 | 0.167 | 0.167 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0013 | 0.0251 | 0.0409 |
Brugia malayi | ecdysone receptor | 0.0018 | 0.0519 | 0.0519 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0037 | 0.167 | 0.2262 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0037 | 0.167 | 0.2108 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.001 | 0.005 | 0.5 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0018 | 0.0519 | 0.0703 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3197 | 0.3197 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0045 | 0.2135 | 0.8925 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0018 | 0.0519 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.167 | 0.167 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0011 | 0.0144 | 0.0234 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Leishmania major | cathepsin L-like protease | 0.0013 | 0.0251 | 0.0863 |
Onchocerca volvulus | 0.0013 | 0.0251 | 0.1011 | |
Brugia malayi | Nuclear hormone receptor E75 | 0.0018 | 0.0519 | 0.0519 |
Brugia malayi | bZIP transcription factor family protein | 0.0066 | 0.3302 | 0.3302 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0039 | 0.1766 | 0.7348 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0057 | 0.2833 | 0.4612 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0114 | 0.6142 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0037 | 0.167 | 0.2718 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0251 | 0.0251 |
Onchocerca volvulus | 0.0018 | 0.0519 | 0.2089 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Loa Loa (eye worm) | DR-78 | 0.0018 | 0.0519 | 0.0519 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.002 | 0.0642 | 0.0689 |
Leishmania major | cathepsin L-like protease | 0.0013 | 0.0251 | 0.0863 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0037 | 0.167 | 0.167 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0037 | 0.167 | 0.167 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0037 | 0.167 | 0.2262 |
Leishmania major | cathepsin L-like protease | 0.005 | 0.2386 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0642 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0642 | 0.0642 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0642 | 0.087 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.167 | 0.167 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0011 | 0.0144 | 0.0195 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0013 | 0.0251 | 0.0148 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0018 | 0.0519 | 0.0519 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0013 | 0.0251 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0037 | 0.167 | 0.167 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0057 | 0.2833 | 0.3715 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Leishmania major | cathepsin L-like protease | 0.0013 | 0.0251 | 0.0863 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0519 | 0.0518 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0251 | 0.0251 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0037 | 0.167 | 0.2718 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0037 | 0.167 | 0.167 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0037 | 0.167 | 0.167 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0013 | 0.0251 | 0.0148 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0037 | 0.167 | 0.167 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0136 | 0.7381 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0037 | 0.167 | 0.2262 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.005 | 0.2386 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0519 | 0.0519 |
Echinococcus multilocularis | jun protein | 0.0066 | 0.3302 | 0.4363 |
Onchocerca volvulus | Cathepsin L homolog | 0.0013 | 0.0251 | 0.1011 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0037 | 0.167 | 0.6723 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0642 | 0.0642 |
Onchocerca volvulus | 0.0051 | 0.2483 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0013 | 0.0251 | 0.0863 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0013 | 0.0251 | 0.0409 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0149 | 0.0149 |
Onchocerca volvulus | Netrin receptor homolog | 0.0011 | 0.0144 | 0.0579 |
Brugia malayi | nuclear receptor RXR | 0.0018 | 0.0519 | 0.0519 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.005 | 0.2386 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0013 | 0.0251 | 0.0148 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0018 | 0.0519 | 0.0518 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0251 | 0.0251 |
Onchocerca volvulus | 0.0013 | 0.0251 | 0.1011 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0519 | 0.0703 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0018 | 0.0519 | 0.0703 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.5203 | 0.7049 |
Brugia malayi | nuclear receptor NHR-88 | 0.0037 | 0.167 | 0.167 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0037 | 0.167 | 0.2262 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0095 | 0.4992 | 0.6698 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.001 | 0.005 | 0.005 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0011 | 0.0144 | 0.0234 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0013 | 0.0251 | 0.0251 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0037 | 0.167 | 0.2718 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0013 | 0.0251 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0037 | 0.167 | 0.2262 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0037 | 0.167 | 0.167 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0037 | 0.167 | 0.6723 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0519 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.167 | 0.167 |
Schistosoma mansoni | nuclear hormone receptor | 0.0037 | 0.167 | 0.2262 |
Onchocerca volvulus | 0.0037 | 0.167 | 0.6723 | |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0018 | 0.0519 | 0.0519 |
Brugia malayi | ecdysteroid receptor | 0.0037 | 0.167 | 0.167 |
Loa Loa (eye worm) | CYP4Cod1 | 0.001 | 0.005 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0251 | 0.0251 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0642 | 0.0642 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0013 | 0.0251 | 1 |
Brugia malayi | steroid hormone receptor | 0.0037 | 0.167 | 0.167 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0018 | 0.0519 | 0.0518 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0037 | 0.167 | 0.167 |
Leishmania major | cathepsin L-like protease | 0.0013 | 0.0251 | 0.0863 |
Brugia malayi | nuclear receptor RXR | 0.002 | 0.0642 | 0.0642 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | 0 | Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNL | ChEMBL. | 17461565 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.