Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.003 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0092 | 0.1008 | 0.1667 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0016 | 0.003 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.003 | 0.0049 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0014 | 0.000000010526 | 0.000000010526 |
Echinococcus granulosus | agrin | 0.0021 | 0.0086 | 0.0209 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0046 | 0.0417 | 0.1016 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0022 | 0.0104 | 0.0104 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0182 | 0.2179 | 0.2179 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0047 | 0.0425 | 0.1034 |
Brugia malayi | ecdysteroid receptor | 0.0047 | 0.0425 | 0.0702 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0021 | 0.0086 | 0.0222 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0022 | 0.0104 | 0.0254 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0092 | 0.1008 | 0.1667 |
Echinococcus granulosus | jun protein | 0.0082 | 0.0879 | 0.2139 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0624 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0047 | 0.0425 | 0.0702 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0014 | 0.000000010526 | 0.000000025621 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0047 | 0.0425 | 0.1034 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.003 | 0.003 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0022 | 0.0104 | 0.0104 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0047 | 0.0425 | 0.0702 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0417 | 0.1016 |
Onchocerca volvulus | 0.003 | 0.021 | 0.2082 | |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0021 | 0.0086 | 0.0142 |
Echinococcus granulosus | organic anion transporting polypeptide 30B | 0.003 | 0.021 | 0.0511 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0025 | 0.0139 | 0.0229 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0417 | 0.069 |
Trypanosoma cruzi | MFS transporter, putative | 0.003 | 0.021 | 0.3029 |
Brugia malayi | secreted modular calcium-binding protein 1 | 0.0021 | 0.0086 | 0.0142 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.003 | 0.003 |
Onchocerca volvulus | 0.0047 | 0.0425 | 0.4212 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.021 | 0.0347 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0047 | 0.0425 | 0.0702 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.017 | 0.2014 | 0.2014 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.003 | 0.0049 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0047 | 0.0425 | 0.1034 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0047 | 0.0425 | 0.4212 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0047 | 0.0425 | 0.0702 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0022 | 0.0104 | 0.0104 |
Onchocerca volvulus | 0.003 | 0.021 | 0.2082 | |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.003 | 0.0049 |
Schistosoma mansoni | nuclear receptor | 0.0022 | 0.0104 | 0.0254 |
Loa Loa (eye worm) | cysteine protease | 0.0016 | 0.003 | 0.0049 |
Onchocerca volvulus | 0.0016 | 0.003 | 0.0296 | |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.068 | 0.1656 |
Echinococcus granulosus | follistatin | 0.0021 | 0.0086 | 0.0209 |
Schistosoma mansoni | agrin | 0.0021 | 0.0086 | 0.0209 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0025 | 0.0139 | 0.0338 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0139 | 0.0229 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0053 | 0.05 | 0.1218 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0047 | 0.0425 | 0.1034 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0047 | 0.0425 | 0.0702 |
Onchocerca volvulus | Cathepsin F homolog | 0.0016 | 0.003 | 0.0296 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0082 | 0.0879 | 0.0879 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0047 | 0.0425 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0139 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Echinococcus multilocularis | follistatin | 0.0021 | 0.0086 | 0.0086 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0025 | 0.0139 | 0.0338 |
Brugia malayi | SPARC precursor | 0.0021 | 0.0086 | 0.0142 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.003 | 0.0296 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.003 | 0.003 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0022 | 0.0104 | 0.0173 |
Schistosoma mansoni | tyrosinase precursor | 0.0092 | 0.1008 | 0.2454 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0417 | 0.1016 |
Loa Loa (eye worm) | ctsf protein | 0.0016 | 0.003 | 0.0049 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.003 | 0.003 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0047 | 0.0425 | 0.0425 |
Echinococcus multilocularis | geminin | 0.0331 | 0.4109 | 0.4109 |
Brugia malayi | Death domain containing protein | 0.0014 | 0.000000010526 | 0.000000017399 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.021 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0139 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0139 | 0.0229 |
Brugia malayi | ecdysone receptor | 0.0022 | 0.0104 | 0.0173 |
Onchocerca volvulus | 0.0016 | 0.003 | 0.0296 | |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0047 | 0.0425 | 0.0425 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0139 | 0.0229 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0123 | 0.1408 | 0.1408 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0022 | 0.0104 | 0.0173 |
Brugia malayi | prostaglandin transporter | 0.003 | 0.021 | 0.0347 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0016 | 0.003 | 0.0073 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0086 | 0.0142 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0047 | 0.0425 | 0.1034 |
Onchocerca volvulus | 0.0092 | 0.1008 | 1 | |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.05 | 0.0827 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1008 | 0.1667 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0022 | 0.0104 | 0.0254 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.003 | 0.0049 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.0022 | 0.0104 | 0.0254 |
Brugia malayi | nuclear hormone receptor | 0.0022 | 0.0104 | 0.0173 |
Loa Loa (eye worm) | fibroinase | 0.0016 | 0.003 | 0.0049 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0047 | 0.0425 | 0.0702 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0092 | 0.1008 | 0.1667 |
Onchocerca volvulus | 0.0016 | 0.003 | 0.0296 | |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.003 | 0.003 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0025 | 0.0139 | 0.0229 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0047 | 0.0425 | 0.0702 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.003 | 0.021 | 0.0347 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0047 | 0.0425 | 0.0702 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0047 | 0.0425 | 0.1034 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0046 | 0.0417 | 0.069 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0047 | 0.0425 | 0.0425 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0016 | 0.003 | 0.0049 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0047 | 0.0425 | 0.1034 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0021 | 0.0086 | 0.0222 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0072 | 0.0748 | 0.1822 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0624 | 1 |
Echinococcus granulosus | Solute carrier organic anion transporter family | 0.003 | 0.021 | 0.0511 |
Onchocerca volvulus | Putative organic anion transporter | 0.003 | 0.021 | 0.2082 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0046 | 0.0417 | 0.4139 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.021 | 0.0347 |
Brugia malayi | Uncoordinated protein 44 | 0.0014 | 0.000000010526 | 0.000000017399 |
Onchocerca volvulus | 0.0092 | 0.1008 | 1 | |
Onchocerca volvulus | 0.0021 | 0.0086 | 0.085 | |
Brugia malayi | hypothetical protein | 0.003 | 0.021 | 0.0347 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.003 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0425 | 0.0702 |
Echinococcus granulosus | cathepsin l1 | 0.0016 | 0.003 | 0.0073 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0022 | 0.0104 | 0.0173 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0047 | 0.0425 | 0.1034 |
Brugia malayi | nuclear receptor NHR-67 | 0.0022 | 0.0104 | 0.0173 |
Brugia malayi | nuclear receptor RXR | 0.0025 | 0.0139 | 0.0229 |
Loa Loa (eye worm) | kazal-type serine protease inhibitor domain-containing protein | 0.0021 | 0.0086 | 0.0142 |
Brugia malayi | nuclear hormone receptor | 0.0047 | 0.0425 | 0.0702 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.0092 | 0.1008 | 0.1667 |
Brugia malayi | nuclear receptor RXR | 0.0022 | 0.0104 | 0.0173 |
Schistosoma mansoni | thyroid hormone receptor | 0.017 | 0.2014 | 0.4903 |
Echinococcus multilocularis | Ankyrin | 0.0014 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0047 | 0.0425 | 0.1034 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0092 | 0.1008 | 0.1667 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0021 | 0.0086 | 0.0222 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0047 | 0.0425 | 0.0425 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0072 | 0.0748 | 0.0748 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1008 | 0.1667 |
Onchocerca volvulus | 0.003 | 0.021 | 0.2082 | |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0425 | 0.0702 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0016 | 0.003 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.1408 | 0.3427 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0047 | 0.0425 | 0.0425 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.003 | 0.0049 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0047 | 0.0425 | 0.0702 |
Schistosoma mansoni | hypothetical protein | 0.0331 | 0.4109 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.003 | 0.0049 |
Echinococcus granulosus | geminin | 0.0331 | 0.4109 | 1 |
Onchocerca volvulus | 0.0046 | 0.0417 | 0.4139 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0143 | 0.167 | 0.4064 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0624 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0047 | 0.0425 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0047 | 0.0425 | 0.0702 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.003 | 0.5 |
Schistosoma mansoni | nuclear receptor | 0.0022 | 0.0104 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0417 | 0.069 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0047 | 0.0425 | 0.1034 |
Schistosoma mansoni | jun-related protein | 0.0067 | 0.068 | 0.1656 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0022 | 0.0104 | 0.0254 |
Onchocerca volvulus | Putative organic anion transporter | 0.003 | 0.021 | 0.2082 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.0624 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0047 | 0.0425 | 0.0425 |
Echinococcus multilocularis | agrin | 0.0021 | 0.0086 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0425 | 0.0702 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0092 | 0.1008 | 0.1667 |
Onchocerca volvulus | 0.0092 | 0.1008 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.003 | 0.0073 |
Brugia malayi | follicle stimulating hormone receptor | 0.0228 | 0.2774 | 0.4584 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0021 | 0.0086 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.021 | 0.0347 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0182 | 0.2179 | 0.5303 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0047 | 0.0425 | 0.1034 |
Brugia malayi | nuclear receptor NHR-88 | 0.0022 | 0.0104 | 0.0173 |
Echinococcus granulosus | FTZ F1 alpha | 0.0047 | 0.0425 | 0.1034 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0118 | 0.1349 | 0.1349 |
Onchocerca volvulus | 0.0016 | 0.003 | 0.0296 | |
Onchocerca volvulus | Putative organic anion transporter | 0.003 | 0.021 | 0.2082 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0022 | 0.0104 | 0.0173 |
Onchocerca volvulus | 0.0064 | 0.0651 | 0.6458 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0047 | 0.0425 | 0.0702 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0047 | 0.0425 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0086 | 0.0142 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0016 | 0.003 | 0.0049 |
Onchocerca volvulus | 0.0022 | 0.0104 | 0.1035 | |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0053 | 0.05 | 0.1218 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0022 | 0.0104 | 0.0173 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0057 | 0.0554 | 0.8824 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0047 | 0.0425 | 0.4212 |
Entamoeba histolytica | cysteine protease, putative | 0.0016 | 0.003 | 0.5 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.003 | 0.021 | 0.0347 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.003 | 0.5 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0047 | 0.0425 | 0.1034 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.05 | 0.0827 |
Brugia malayi | tailless protein | 0.0022 | 0.0104 | 0.0173 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0651 | 0.1076 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.021 | 0.0347 |
Schistosoma mansoni | nuclear hormone receptor | 0.0047 | 0.0425 | 0.1034 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0022 | 0.0104 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Onchocerca volvulus | 0.0016 | 0.003 | 0.0296 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0022 | 0.0104 | 0.0104 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0143 | 0.167 | 0.4064 |
Onchocerca volvulus | 0.003 | 0.021 | 0.2082 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0624 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.003 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0331 | 0.4109 | 1 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0014 | 0.0002 | 0.0004 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.003 | 0.003 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0053 | 0.05 | 0.1218 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0425 | 0.0702 |
Onchocerca volvulus | 0.0092 | 0.1008 | 1 | |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0046 | 0.0417 | 0.1016 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0022 | 0.0104 | 0.0254 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0047 | 0.0425 | 0.0425 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0047 | 0.0425 | 0.0702 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0046 | 0.0417 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Toxoplasma gondii | transporter, major facilitator family protein | 0.003 | 0.021 | 0.0717 |
Schistosoma mansoni | hypothetical protein | 0.0281 | 0.3459 | 0.842 |
Brugia malayi | conserved hypotetical protein | 0.0022 | 0.0104 | 0.0173 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0425 | 0.0702 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0047 | 0.0425 | 0.0702 |
Schistosoma mansoni | nuclear hormone receptor | 0.0022 | 0.0104 | 0.0254 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.0092 | 0.1008 | 0.1667 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0022 | 0.0104 | 0.0254 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0624 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0022 | 0.0104 | 0.1035 |
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.021 | 0.254 | 1 |
Onchocerca volvulus | 0.003 | 0.021 | 0.2082 | |
Schistosoma mansoni | organic anion transporter | 0.003 | 0.021 | 0.0511 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0139 | 0.0229 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0022 | 0.0104 | 0.0254 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0016 | 0.003 | 0.0073 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0047 | 0.0425 | 0.0425 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0047 | 0.0425 | 0.0702 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0228 | 0.2774 | 0.4584 |
Echinococcus multilocularis | organic anion transporting polypeptide 30B | 0.003 | 0.021 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0086 | 0.0142 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.003 | 0.0296 |
Echinococcus granulosus | Ankyrin | 0.0014 | 0.0002 | 0.0004 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0047 | 0.0425 | 0.1034 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Loa Loa (eye worm) | sodium-independent organic anion transporter | 0.003 | 0.021 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.021 | 0.0347 |
Loa Loa (eye worm) | DR-78 | 0.0022 | 0.0104 | 0.0173 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0022 | 0.0104 | 0.0104 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0021 | 0.0086 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0086 | 0.0142 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0025 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0425 | 0.0702 |
Echinococcus multilocularis | jun protein | 0.0082 | 0.0879 | 0.0879 |
Echinococcus multilocularis | Solute carrier organic anion transporter family | 0.003 | 0.021 | 0.021 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0022 | 0.0104 | 0.1035 |
Onchocerca volvulus | 0.0016 | 0.003 | 0.0296 | |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0047 | 0.0425 | 0.0702 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0047 | 0.0425 | 0.0702 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Schistosoma mansoni | tyrosinase precursor | 0.0092 | 0.1008 | 0.2454 |
Schistosoma mansoni | thyroid hormone receptor | 0.017 | 0.2014 | 0.4903 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0047 | 0.0425 | 0.0702 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0002 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0425 | 0.0702 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0049 | 0.0452 | 0.7098 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Onchocerca volvulus | 0.0016 | 0.003 | 0.0296 | |
Loa Loa (eye worm) | steroid hormone receptor | 0.0047 | 0.0425 | 0.0702 |
Brugia malayi | steroid hormone receptor | 0.0047 | 0.0425 | 0.0702 |
Brugia malayi | Protein kinase domain containing protein | 0.0014 | 0.000000010526 | 0.000000017399 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0022 | 0.0104 | 0.0173 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0014 | 0.000000010526 | 0.000000025621 |
Schistosoma mansoni | follistatin | 0.0021 | 0.0086 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0021 | 0.0086 | 0.0142 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0016 | 0.003 | 0.5 |
Schistosoma mansoni | organic anion transporter | 0.003 | 0.021 | 0.0511 |
Loa Loa (eye worm) | tyrosinase 1 | 0.0092 | 0.1008 | 0.1667 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0022 | 0.0104 | 0.0254 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0624 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.003 | 0.0049 |
Brugia malayi | bZIP transcription factor family protein | 0.0082 | 0.0879 | 0.1453 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0139 | 0.0229 |
Echinococcus multilocularis | expressed protein | 0.0021 | 0.0086 | 0.0086 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0082 | 0.0879 | 0.2139 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0047 | 0.0425 | 0.1034 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0025 | 0.0139 | 0.0229 |
Toxoplasma gondii | protease inhibitor PI2 | 0.0021 | 0.0086 | 0.0222 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Onchocerca volvulus | 0.0022 | 0.0104 | 0.1035 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0047 | 0.0425 | 0.0702 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0053 | 0.05 | 0.05 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0425 | 0.0702 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.05 | 0.0827 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.085 | 0.1405 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0047 | 0.0425 | 0.0702 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0417 | 0.069 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0025 | 0.0139 | 0.0338 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0123 | 0.1408 | 0.3427 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0047 | 0.0425 | 0.0702 |
Brugia malayi | ShTK domain containing protein | 0.0092 | 0.1008 | 0.1667 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.003 | 0.0073 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0022 | 0.0104 | 0.0173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0047 | 0.0425 | 0.4212 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0624 | 0.5 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0022 | 0.0104 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0104 | 0.0173 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0053 | 0.05 | 0.05 |
Schistosoma mansoni | coup transcription factor | 0.0047 | 0.0425 | 0.1034 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0481 | 0.605 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Loa Loa (eye worm) | STAT protein | 0.0481 | 0.605 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0022 | 0.0104 | 0.0254 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.003 | 0.021 | 0.0347 |
Brugia malayi | hypothetical protein | 0.003 | 0.021 | 0.0347 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0046 | 0.0417 | 0.1016 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0047 | 0.0425 | 0.0702 |
Loa Loa (eye worm) | agrin synaptic family protein | 0.0021 | 0.0086 | 0.0142 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0022 | 0.0104 | 0.0254 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0021 | 0.0086 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.021 | 0.0347 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0046 | 0.0417 | 0.0417 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.003 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0047 | 0.0425 | 0.1034 |
Schistosoma mansoni | nuclear hormone receptor | 0.0022 | 0.0104 | 0.0254 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 80 % | Inhibition of human recombinant ATX at 1 uM after 16 hrs | ChEMBL. | 17257836 |
Inhibition (binding) | = 80 % | Inhibition of human recombinant ATX at 10 uM after 16 hrs | ChEMBL. | 17257836 |
Inhibition (binding) | = 80 % | Inhibition of human recombinant ATX at 100 uM after 16 hrs | ChEMBL. | 17257836 |
Inhibition (binding) | = 80 % | Inhibition of human recombinant ATX at 1 uM after 16 hrs | ChEMBL. | 17257836 |
Inhibition (binding) | = 80 % | Inhibition of human recombinant ATX at 10 uM after 16 hrs | ChEMBL. | 17257836 |
Inhibition (binding) | = 80 % | Inhibition of human recombinant ATX at 100 uM after 16 hrs | ChEMBL. | 17257836 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.