Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0329 | 0.7939 | 0.7939 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0906 | 0.0906 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0906 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0329 | 0.7939 | 0.7939 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0906 | 0.0798 |
Schistosoma mansoni | nuclear hormone receptor | 0.0155 | 0.3241 | 0.3186 |
Onchocerca volvulus | 0.0155 | 0.3241 | 0.3241 | |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0329 | 0.7939 | 0.7922 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0059 | 0.0634 | 0.0634 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0155 | 0.3241 | 0.3241 |
Brugia malayi | nuclear hormone receptor | 0.0155 | 0.3241 | 0.3241 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0906 | 0.0798 |
Onchocerca volvulus | 0.0155 | 0.3241 | 0.3241 | |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.0184 | 0.4029 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0329 | 0.7939 | 0.7939 |
Plasmodium falciparum | amino acid transporter, putative | 0.0069 | 0.0906 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0329 | 0.7939 | 0.7939 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0069 | 0.0906 | 0.0832 |
Brugia malayi | RNA binding protein | 0.0066 | 0.0841 | 0.0841 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0069 | 0.0906 | 0.0832 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.3744 | 0.367 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0069 | 0.0906 | 0.0906 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0329 | 0.7939 | 0.7939 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0329 | 0.7939 | 0.7939 |
Brugia malayi | nuclear receptor NHR-88 | 0.0329 | 0.7939 | 0.7939 |
Brugia malayi | nuclear receptor RXR | 0.0174 | 0.3744 | 0.3744 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.7939 | 0.7915 |
Schistosoma mansoni | single-minded | 0.0048 | 0.0335 | 0.0256 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0329 | 0.7939 | 0.7939 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0155 | 0.3241 | 0.3241 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0906 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.3744 | 0.367 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0329 | 0.7939 | 0.7939 |
Brugia malayi | hypothetical protein | 0.0174 | 0.3744 | 0.3744 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0906 | 0.0906 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0087 | 0.1396 | 0.5947 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0069 | 0.0906 | 0.0832 |
Leishmania major | cytochrome p450-like protein | 0.004 | 0.0117 | 0.5 |
Schistosoma mansoni | gabp alpha | 0.0076 | 0.1098 | 0.1025 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0155 | 0.3241 | 0.3241 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0841 | 0.0766 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.3744 | 0.367 |
Toxoplasma gondii | hypothetical protein | 0.0069 | 0.0906 | 0.5 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0122 | 0.2347 | 1 |
Brugia malayi | hypothetical protein | 0.0174 | 0.3744 | 0.3744 |
Brugia malayi | hypothetical protein | 0.0069 | 0.0906 | 0.0906 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0155 | 0.3241 | 0.3186 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0155 | 0.3241 | 0.3161 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0329 | 0.7939 | 0.7922 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.0841 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.7939 | 0.7915 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0155 | 0.3241 | 0.3241 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0155 | 0.3241 | 0.3241 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0329 | 0.7939 | 0.7939 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0069 | 0.0906 | 0.0906 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0405 | 1 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0329 | 0.7939 | 0.7915 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.2308 | 0.2217 |
Brugia malayi | ecdysteroid receptor | 0.0329 | 0.7939 | 0.7939 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.7939 | 0.7915 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.0841 | 0.0841 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0906 | 0.0798 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0174 | 0.3744 | 0.3744 |
Plasmodium vivax | amine transporter, putative | 0.0069 | 0.0906 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0329 | 0.7939 | 0.7939 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.3368 | 0.3289 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0184 | 0.4029 | 0.5 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0906 | 0.0906 |
Brugia malayi | hypothetical protein | 0.0155 | 0.3241 | 0.3241 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0155 | 0.3241 | 0.3241 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0069 | 0.0906 | 0.0832 |
Brugia malayi | hypoxia-induced factor 1 | 0.0147 | 0.3033 | 0.3033 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0076 | 0.1098 | 0.1098 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0076 | 0.1098 | 0.1098 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0069 | 0.0906 | 0.0906 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0155 | 0.3241 | 0.3241 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0329 | 0.7939 | 0.7922 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0343 | 0.0343 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0069 | 0.0906 | 0.0906 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0069 | 0.0906 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Loa Loa (eye worm) | DR-78 | 0.0155 | 0.3241 | 0.3161 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.3744 | 0.367 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0329 | 0.7939 | 0.7939 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0069 | 0.0906 | 0.0906 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0155 | 0.3241 | 0.3241 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.2816 | 0.2757 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0329 | 0.7939 | 0.7939 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0081 | 0.1236 | 0.1132 |
Brugia malayi | steroid hormone receptor | 0.0329 | 0.7939 | 0.7939 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0329 | 0.7939 | 0.7915 |
Echinococcus granulosus | FTZ F1 alpha | 0.0329 | 0.7939 | 0.7939 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0087 | 0.1396 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0329 | 0.7939 | 0.7922 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.7939 | 0.7915 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0155 | 0.3241 | 0.3241 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0155 | 0.3241 | 0.3241 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0069 | 0.0906 | 0.0906 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0155 | 0.3241 | 0.3186 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.0841 | 0.0841 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0329 | 0.7939 | 0.7939 |
Trypanosoma cruzi | cytochrome P450, putative | 0.004 | 0.0117 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0081 | 0.0081 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0329 | 0.7939 | 0.7922 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0343 | 0.0343 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0329 | 0.7939 | 0.7939 |
Trypanosoma brucei | cytochrome P450, putative | 0.004 | 0.0117 | 0.5 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0069 | 0.0906 | 0.0832 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.1098 | 0.1098 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0069 | 0.0906 | 0.0906 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0069 | 0.0906 | 0.0832 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0155 | 0.3241 | 0.3241 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0906 | 0.0798 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0155 | 0.3241 | 0.3241 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.004 | 0.0117 | 0.0499 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0155 | 0.3241 | 0.3241 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0906 | 0.0798 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0062 | 0.0729 | 0.3105 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0048 | 0.0335 | 0.0256 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0155 | 0.3241 | 0.3161 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0329 | 0.7939 | 0.7915 |
Brugia malayi | hypothetical protein | 0.016 | 0.3368 | 0.3368 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0329 | 0.7939 | 0.7939 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0343 | 0.0264 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0069 | 0.0906 | 0.0832 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0841 | 0.0766 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0329 | 0.7939 | 0.7915 |
Brugia malayi | PAS domain containing protein | 0.0048 | 0.0335 | 0.0335 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0906 | 0.0798 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0329 | 0.7939 | 0.7915 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0155 | 0.3241 | 0.3161 |
Brugia malayi | hypothetical protein | 0.0135 | 0.2689 | 0.2689 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0069 | 0.0906 | 0.0906 |
Loa Loa (eye worm) | serotonin transporter b | 0.0405 | 1 | 1 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0405 | 1 | 1 |
Brugia malayi | ecdysone receptor | 0.0155 | 0.3241 | 0.3241 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0172 | 0.3685 | 0.3685 |
Onchocerca volvulus | 0.0069 | 0.0906 | 0.0906 | |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.3744 | 0.367 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0343 | 0.0264 |
Brugia malayi | Cytochrome P450 family protein | 0.004 | 0.0117 | 0.0117 |
Brugia malayi | tailless protein | 0.0155 | 0.3241 | 0.3241 |
Brugia malayi | nuclear receptor NHR-67 | 0.0155 | 0.3241 | 0.3241 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0329 | 0.7939 | 0.7939 |
Brugia malayi | hypothetical protein | 0.0155 | 0.3241 | 0.3241 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0906 | 0.0798 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0155 | 0.3241 | 0.3241 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0155 | 0.3241 | 0.3241 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0062 | 0.0729 | 0.3105 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0155 | 0.3241 | 0.3241 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0329 | 0.7939 | 0.7922 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0343 | 0.0343 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0329 | 0.7939 | 0.7922 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0174 | 0.3744 | 0.3693 |
Onchocerca volvulus | 0.0329 | 0.7939 | 0.7939 | |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0329 | 0.7939 | 0.7939 |
Onchocerca volvulus | 0.0135 | 0.2689 | 0.2689 | |
Loa Loa (eye worm) | hypothetical protein | 0.0405 | 1 | 1 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0076 | 0.1098 | 0.0993 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0069 | 0.0906 | 0.0832 |
Schistosoma mansoni | thyroid hormone receptor | 0.0329 | 0.7939 | 0.7922 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Schistosoma mansoni | jun-related protein | 0.0139 | 0.2816 | 0.2757 |
Brugia malayi | Cytochrome P450 family protein | 0.0081 | 0.1236 | 0.1236 |
Echinococcus granulosus | jun protein | 0.0172 | 0.3685 | 0.3685 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0329 | 0.7939 | 0.7939 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0329 | 0.7939 | 0.7915 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0081 | 0.0081 |
Trypanosoma cruzi | cytochrome P450, putative | 0.004 | 0.0117 | 0.5 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0184 | 0.4029 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.3557 | 0.3481 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0174 | 0.3744 | 0.3744 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0174 | 0.3744 | 0.3744 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0174 | 0.3744 | 0.3744 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0343 | 0.0228 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0329 | 0.7939 | 0.7939 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0155 | 0.3241 | 0.3241 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0343 | 0.0343 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0329 | 0.7939 | 0.7939 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0841 | 0.0766 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0329 | 0.7939 | 0.7939 |
Brugia malayi | Cytochrome P450 family protein | 0.004 | 0.0117 | 0.0117 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0329 | 0.7939 | 0.7922 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0081 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0069 | 0.0906 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.0841 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Schistosoma mansoni | ets-related | 0.023 | 0.5275 | 0.5237 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.0841 | 0.0841 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0081 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0172 | 0.3685 | 0.3685 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0147 | 0.3033 | 0.295 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0155 | 0.3241 | 0.3241 |
Schistosoma mansoni | nuclear receptor | 0.0155 | 0.3241 | 0.3186 |
Brugia malayi | nuclear hormone receptor | 0.0329 | 0.7939 | 0.7939 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0081 | 0.5 |
Brugia malayi | conserved hypotetical protein | 0.0155 | 0.3241 | 0.3241 |
Loa Loa (eye worm) | hypothetical protein | 0.0405 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0329 | 0.7939 | 0.7922 |
Onchocerca volvulus | 0.0069 | 0.0906 | 0.0906 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0155 | 0.3241 | 0.3186 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0069 | 0.0906 | 0.0832 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0081 | 0.0081 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0069 | 0.0906 | 0.0832 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.0841 | 0.0733 |
Plasmodium vivax | hypothetical protein, conserved | 0.0069 | 0.0906 | 0.5 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0069 | 0.0906 | 0.0832 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0329 | 0.7939 | 0.7915 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0329 | 0.7939 | 0.7939 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0329 | 0.7939 | 0.7939 |
Schistosoma mansoni | zinc finger protein | 0.0155 | 0.3241 | 0.3186 |
Schistosoma mansoni | nuclear receptor | 0.0155 | 0.3241 | 0.3186 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0906 | 0.0798 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.7939 | 0.7915 |
Onchocerca volvulus | 0.0069 | 0.0906 | 0.0906 | |
Onchocerca volvulus | Bile acid receptor homolog | 0.0329 | 0.7939 | 0.7939 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0841 | 0.0766 |
Schistosoma mansoni | nuclear hormone receptor | 0.0329 | 0.7939 | 0.7922 |
Brugia malayi | hypothetical protein | 0.0285 | 0.675 | 0.675 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.7939 | 0.7915 |
Schistosoma mansoni | coup transcription factor | 0.0329 | 0.7939 | 0.7922 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Brugia malayi | Fli-1 protein | 0.023 | 0.5275 | 0.5275 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0841 | 0.0766 |
Echinococcus multilocularis | serotonin transporter | 0.0405 | 1 | 1 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0405 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0329 | 0.7939 | 0.7939 |
Loa Loa (eye worm) | fli-1 protein | 0.023 | 0.5275 | 0.5219 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0405 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0329 | 0.7939 | 0.7939 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0081 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0329 | 0.7939 | 0.7915 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0155 | 0.3241 | 0.3241 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0329 | 0.7939 | 0.7939 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0069 | 0.0906 | 0.0906 |
Brugia malayi | nuclear receptor NHR-88 | 0.0155 | 0.3241 | 0.3241 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0329 | 0.7939 | 0.7939 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0329 | 0.7939 | 0.7939 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0405 | 1 | 1 |
Echinococcus multilocularis | jun protein | 0.0172 | 0.3685 | 0.3685 |
Schistosoma mansoni | lipoxygenase | 0.0059 | 0.0634 | 0.0557 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0155 | 0.3241 | 0.3186 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.7939 | 0.7915 |
Plasmodium falciparum | transporter, putative | 0.0069 | 0.0906 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0329 | 0.7939 | 0.7939 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0155 | 0.3241 | 0.3241 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0329 | 0.7939 | 0.7939 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0906 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0329 | 0.7939 | 0.7939 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0343 | 0.0264 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0329 | 0.7939 | 0.7922 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0329 | 0.7939 | 0.7939 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.0841 | 0.0841 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0906 | 0.0798 |
Echinococcus granulosus | serotonin transporter | 0.0405 | 1 | 1 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.1098 | 0.1098 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3241 | 0.3161 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0174 | 0.3744 | 0.3693 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0329 | 0.7939 | 0.7939 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0059 | 0.0634 | 0.0634 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0329 | 0.7939 | 0.7939 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0174 | 0.3744 | 0.367 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0055 | 0.0524 | 0.2231 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0069 | 0.0906 | 0.0906 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0069 | 0.0906 | 0.0906 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0801 | 0.0692 |
Onchocerca volvulus | 0.0405 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0405 | 1 | 1 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0087 | 0.1396 | 0.5947 |
Brugia malayi | nuclear receptor RXR | 0.0155 | 0.3241 | 0.3241 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.7939 | 0.7915 |
Brugia malayi | bZIP transcription factor family protein | 0.0172 | 0.3685 | 0.3685 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0329 | 0.7939 | 0.7939 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0069 | 0.0906 | 0.0906 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Diet (functional) | < 47 % | In vivo Triglyceride lowering activity at a dose of 0.10 % of the diet | ChEMBL. | 6604818 |
Diet (functional) | < 58 % | In vivo Triglyceride lowering activity at dose as 0.03 % of the diet | ChEMBL. | 6604818 |
Diet (functional) | < 69 % | In vivo Triglyceride lowering activity at dose as 0.01 % of the diet | ChEMBL. | 6604818 |
Diet (functional) | < 82 % | In vivo sterol lowering activity at dose of 0.10 % of the diet | ChEMBL. | 6604818 |
Diet (functional) | = 90 % | In vivo sterol lowering activity, dosed as 0.03 % of the diet | ChEMBL. | 6604818 |
Diet (functional) | = 100 % | In vivo Sterol lowering activity at dose as 0.01% of the diet | ChEMBL. | 6604818 |
Inhibition (binding) | = 12 % | In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase | ChEMBL. | 6604818 |
Inhibition (binding) | = 12 % | In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase | ChEMBL. | 6604818 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.