Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | sterol regulatory element binding protein | 0.0045 | 0.0035 | 0.0076 |
Echinococcus granulosus | geminin | 0.0175 | 0.0431 | 0.0932 |
Mycobacterium tuberculosis | Probable peptidoglycan hydrolase | 0.0523 | 0.1483 | 1 |
Loa Loa (eye worm) | matrixin family protein | 0.0952 | 0.2783 | 0.9146 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.005 | 0.0052 | 0.0292 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0039 | 0.0019 | 0.0019 |
Echinococcus granulosus | glycogen phosphorylase | 0.1007 | 0.2948 | 0.6374 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0009 | 0.0029 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.023 | 0.0597 | 0.4026 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.005 | 0.0052 | 0.0137 |
Brugia malayi | CHE-14 protein | 0.0045 | 0.0035 | 0.0115 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0039 | 0.0019 | 0.0035 |
Brugia malayi | Matrixin family protein | 0.1038 | 0.3042 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1007 | 0.2948 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.005 | 0.0052 | 0.0137 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0076 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0014 | 0.0045 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.1007 | 0.2948 | 0.9691 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0009 | 0.006 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0131 | 0.0405 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0012 | 0.001 |
Toxoplasma gondii | exonuclease III APE | 0.0039 | 0.0019 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0039 | 0.0019 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.025 | 0.0657 | 0.216 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1007 | 0.2948 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0036 | 0.0007 | 0.0049 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0009 | 0.003 |
Brugia malayi | Matrixin family protein | 0.0429 | 0.12 | 0.3943 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.005 | 0.0052 | 0.0351 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0012 | 0.2733 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.005 | 0.0052 | 0.0292 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0052 | 0.0058 | 0.0197 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.0105 | 0.0219 | 0.0705 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0009 | 0.006 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0149 | 0.035 | 0.035 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.0116 | 0.0382 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0039 | 0.0019 | 0.0063 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0012 | 0.004 |
Onchocerca volvulus | 0.0429 | 0.12 | 0.405 | |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0104 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0429 | 0.12 | 0.3943 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.0105 | 0.0219 | 0.0705 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0009 | 0.0029 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0131 | 0.0405 |
Echinococcus multilocularis | protein patched | 0.0045 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0609 | 0.1743 | 0.5898 | |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0012 | 0.2733 |
Brugia malayi | carbohydrate phosphorylase | 0.1007 | 0.2948 | 0.9691 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0105 | 0.0216 | 0.0711 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0076 | 0.0131 | 0.0283 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.025 | 0.0657 | 0.1421 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0009 | 0.006 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0039 | 0.0019 | 0.0042 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.005 | 0.0052 | 0.0292 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0039 | 0.0019 | 0.2397 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0038 | 0.0014 | 0.0031 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.003 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.12 | 0.3943 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1007 | 0.2948 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0104 | 0.0215 | 0.0465 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0009 | 0.006 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0012 | 0.001 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0012 | 0.004 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0039 | 0.0019 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1007 | 0.2948 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.0186 | 0.0403 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0038 | 0.0014 | 0.4459 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0014 | 0.0045 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0106 | 0.022 | 0.0746 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0009 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0014 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0058 | 0.0191 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0105 | 0.0216 | 0.0711 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0054 | 0.0184 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0009 | 0.006 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.005 | 0.0052 | 0.0351 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0009 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0216 | 0.0711 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0066 | 0.0216 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0052 | 0.0351 |
Giardia lamblia | Glycogen phosphorylase | 0.1007 | 0.2948 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.005 | 0.0052 | 0.0137 |
Brugia malayi | Matrixin family protein | 0.0429 | 0.12 | 0.3943 |
Schistosoma mansoni | survival motor neuron protein | 0.0051 | 0.0054 | 0.0184 |
Brugia malayi | Matrixin family protein | 0.0429 | 0.12 | 0.3943 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0039 | 0.0019 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.1007 | 0.2948 | 0.6374 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.0186 | 0.0613 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0748 | 0.2166 | 0.2166 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0051 | 0.0054 | 0.0178 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.005 | 0.0052 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.003 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0009 | 0.0029 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0036 | 0.0007 | 0.0049 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1007 | 0.2948 | 0.2948 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.003 | 0.0103 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0952 | 0.2783 | 0.9436 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.005 | 0.0052 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0431 | 0.1461 |
Onchocerca volvulus | 0.005 | 0.0052 | 0.0147 | |
Schistosoma mansoni | glycogen phosphorylase | 0.1007 | 0.2948 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0035 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0523 | 0.1483 | 0.4874 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0435 | 0.1218 | 0.4107 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0009 | 0.0019 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0131 | 0.0405 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0009 | 0.006 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.0269 | 0.0886 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0104 | 0.0215 | 0.0707 |
Echinococcus multilocularis | expressed conserved protein | 0.0098 | 0.0196 | 0.0196 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0186 | 0.0632 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0039 | 0.0019 | 0.013 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0431 | 0.1461 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.12 | 0.3943 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0009 | 0.0029 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.005 | 0.0052 | 0.0292 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0039 | 0.0019 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0014 | 0.0045 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.1007 | 0.2948 | 0.2948 |
Onchocerca volvulus | Matrilysin homolog | 0.0952 | 0.2783 | 0.9436 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0009 | 0.006 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.1561 | 0.4625 | 0.4625 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0009 | 0.0029 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0012 | 0.0025 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.1561 | 0.4625 | 1 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0104 | 0.0215 | 0.0692 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0035 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0219 | 0.0719 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.005 | 0.0052 | 0.0351 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1007 | 0.2948 | 0.2948 |
Brugia malayi | AMP-binding enzyme family protein | 0.005 | 0.0052 | 0.0171 |
Loa Loa (eye worm) | matrixin family protein | 0.1038 | 0.3042 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0116 | 0.0394 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.1007 | 0.2948 | 1 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0045 | 0.0035 | 0.0115 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0039 | 0.0019 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0435 | 0.1218 | 0.4131 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0052 | 0.0171 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0186 | 0.0632 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0045 | 0.0035 | 0.0076 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0748 | 0.2166 | 0.7345 |
Onchocerca volvulus | Matrilysin homolog | 0.0429 | 0.12 | 0.405 |
Echinococcus multilocularis | protein dispatched 1 | 0.0051 | 0.0054 | 0.0054 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0012 | 0.0019 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0012 | 0.2733 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0012 | 0.0655 |
Echinococcus multilocularis | geminin | 0.0175 | 0.0431 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0052 | 0.0171 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.0186 | 0.0403 |
Brugia malayi | Matrixin family protein | 0.0429 | 0.12 | 0.3943 |
Schistosoma mansoni | glycogen phosphorylase | 0.1007 | 0.2948 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.005 | 0.0052 | 0.0292 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0045 | 0.0035 | 0.0035 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.0186 | 0.0186 |
Schistosoma mansoni | patched 1 | 0.0045 | 0.0035 | 0.0119 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.003 | 0.0103 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0012 | 0.0012 |
Echinococcus granulosus | expressed conserved protein | 0.0098 | 0.0196 | 0.0424 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0009 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0215 | 0.0707 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.025 | 0.0657 | 0.0657 |
Onchocerca volvulus | 0.0052 | 0.0058 | 0.0168 | |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0009 | 0.006 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0435 | 0.1218 | 0.4107 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0039 | 0.0019 | 0.0035 |
Brugia malayi | Hemopexin family protein | 0.0609 | 0.1743 | 0.5728 |
Schistosoma mansoni | ap endonuclease | 0.0039 | 0.0019 | 0.0065 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0039 | 0.0019 | 0.0063 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0748 | 0.2166 | 0.4682 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.0269 | 0.0886 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.005 | 0.0052 | 0.0292 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0009 | 0.0029 |
Schistosoma mansoni | hypothetical protein | 0.0609 | 0.1743 | 0.5911 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0014 | 0.0045 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0036 | 0.0007 | 0.0049 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.005 | 0.0052 | 0.0292 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.005 | 0.0052 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0009 | 0.0029 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0131 | 0.0444 |
Mycobacterium leprae | PROBABLE HYDROLASE | 0.0523 | 0.1483 | 1 |
Brugia malayi | HSF-type DNA-binding domain containing protein | 0.0105 | 0.0219 | 0.0719 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0039 | 0.0019 | 1 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0131 | 0.043 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0076 | 0.0131 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.12 | 0.3943 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.0105 | 0.0219 | 0.0705 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0009 | 0.006 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0009 | 0.003 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0149 | 0.035 | 0.0758 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0105 | 0.0216 | 0.0711 |
Entamoeba histolytica | hypothetical protein | 0.0076 | 0.0131 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0052 | 0.0171 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0036 | 0.0007 | 0.0049 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0186 | 0.0632 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0435 | 0.1218 | 0.8213 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0012 | 0.001 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0435 | 0.1218 | 0.8203 |
Echinococcus multilocularis | tumor protein p63 | 0.0357 | 0.0982 | 0.0982 |
Brugia malayi | AMP-binding enzyme family protein | 0.005 | 0.0052 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0009 | 0.0029 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.1007 | 0.2948 | 0.6374 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0012 | 0.0039 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0429 | 0.12 | 0.4068 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0009 | 0.0029 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0009 | 0.0029 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.0186 | 0.0613 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0012 | 0.0039 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0039 | 0.0019 | 0.5 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0039 | 0.0019 | 0.007 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0012 | 0.2733 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0039 | 0.0019 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0116 | 0.0382 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0523 | 0.1483 | 0.4874 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.0269 | 0.0886 |
Onchocerca volvulus | Heat shock factor protein 2 homolog | 0.0105 | 0.0219 | 0.0714 |
Echinococcus granulosus | tumor protein p63 | 0.0357 | 0.0982 | 0.2123 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.0186 | 0.0186 |
Chlamydia trachomatis | glycogen phosphorylase | 0.1007 | 0.2948 | 1 |
Mycobacterium ulcerans | hydrolase | 0.0523 | 0.1483 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0009 | 0.0029 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0038 | 0.0014 | 0.0091 |
Brugia malayi | AMP-binding enzyme family protein | 0.005 | 0.0052 | 0.0171 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.005 | 0.0052 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0009 | 0.006 |
Schistosoma mansoni | ap endonuclease | 0.0039 | 0.0019 | 0.0065 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.0435 | 0.1218 | 0.4107 |
Onchocerca volvulus | 0.0051 | 0.0054 | 0.0154 | |
Brugia malayi | hypothetical protein | 0.025 | 0.0657 | 0.216 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 1.01 ug ml-1 | Cytotoxicity against human 1A9 cells by sulforhodamine B assay | ChEMBL. | 17643301 |
ED50 (functional) | = 1.01 ug ml-1 | Cytotoxicity against human 1A9 cells by sulforhodamine B assay | ChEMBL. | 17643301 |
ED50 (functional) | = 9.79 ug ml-1 | Cytotoxicity against human KB cells by sulforhodamine B assay | ChEMBL. | 17643301 |
ED50 (functional) | = 9.79 ug ml-1 | Cytotoxicity against human KB cells by sulforhodamine B assay | ChEMBL. | 17643301 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.