Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0923 | 0.5765 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0038 | 0.0169 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0172 | 0.0298 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0145 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0023 | 0.004 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.0154 | 0.0152 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0019 | 0.0008 | 0.0014 |
Plasmodium vivax | plasmepsin IV, putative | 0.0019 | 0.0008 | 0.0156 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0097 | 0.0505 | 1 |
Echinococcus multilocularis | expressed conserved protein | 0.0091 | 0.047 | 0.0468 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.0331 | 0.1994 | 0.3456 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0097 | 0.0505 | 0.0872 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0038 | 0.0061 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0008 | 0.001 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0038 | 0.07 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0025 | 0.0045 | 0.0042 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0097 | 0.0505 | 0.995 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.0154 | 0.0264 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0038 | 0.0169 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.0154 | 0.0264 |
Echinococcus granulosus | expressed conserved protein | 0.0091 | 0.047 | 0.0811 |
Plasmodium falciparum | plasmepsin IX | 0.0019 | 0.0008 | 0.0156 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0264 | 0.0454 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0507 | 0.088 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0019 | 0.0008 | 0.0111 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0466 | 0.2858 | 0.4955 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0025 | 0.0045 | 0.0074 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0019 | 0.0008 | 0.001 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.0264 | 0.0513 |
Trypanosoma brucei | oligopeptidase b | 0.0367 | 0.2226 | 0.3858 |
Leishmania major | oligopeptidase b | 0.0367 | 0.2226 | 0.3858 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0025 | 0.0045 | 0.0074 |
Echinococcus multilocularis | protein dispatched 1 | 0.0048 | 0.0192 | 0.0189 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0139 | 0.0773 | 0.0771 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.0154 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0505 | 0.0876 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0019 | 0.0008 | 0.001 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0097 | 0.0507 | 0.0877 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0008 | 0.0014 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0264 | 0.1187 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0826 | 0.5149 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0264 | 0.0454 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0019 | 0.0008 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0154 | 0.0268 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0038 | 0.0061 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0019 | 0.0008 | 0.001 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0002 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0008 | 0.0014 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0019 | 0.0008 | 0.001 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0038 | 0.0061 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0097 | 0.0505 | 0.0872 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0097 | 0.0505 | 0.0872 |
Plasmodium falciparum | plasmepsin X | 0.0019 | 0.0008 | 0.0156 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0019 | 0.0008 | 0.001 |
Toxoplasma gondii | acylaminoacyl-peptidase, putative | 0.0097 | 0.0505 | 0.0872 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0264 | 0.1187 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0097 | 0.0505 | 0.0872 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0019 | 0.0008 | 0.001 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0172 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0038 | 0.0065 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0097 | 0.0505 | 0.0503 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0038 | 0.0065 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0045 | 0.0845 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0019 | 0.0008 | 0.001 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0097 | 0.0505 | 0.0872 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0097 | 0.0505 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0038 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0008 | 0.0014 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.0154 | 0.0264 |
Plasmodium falciparum | plasmepsin I | 0.0019 | 0.0008 | 0.0156 |
Brugia malayi | Angiotensin-converting enzyme family protein | 0.0161 | 0.0917 | 0.1587 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0002 | 0.0004 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.0154 | 0.0268 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0097 | 0.0505 | 0.0872 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0038 | 0.0169 |
Trypanosoma cruzi | oligopeptidase b | 0.0367 | 0.2226 | 0.3858 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0097 | 0.0505 | 0.0872 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0019 | 0.0008 | 0.001 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0038 | 0.0061 |
Trypanosoma brucei | prolyl oligopeptidase, putative | 0.0367 | 0.2226 | 0.3858 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0172 | 0.0169 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0019 | 0.0008 | 0.0014 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0172 | 0.0294 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0923 | 0.5765 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0097 | 0.0507 | 0.0877 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0097 | 0.0505 | 0.0872 |
Plasmodium vivax | plasmepsin V, putative | 0.0019 | 0.0008 | 0.0156 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0097 | 0.0505 | 0.0872 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0 | 0.5 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0038 | 0.07 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0139 | 0.0773 | 0.1337 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0097 | 0.0505 | 0.0503 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0038 | 0.0169 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0172 | 0.0294 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0038 | 0.07 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0097 | 0.0505 | 0.0872 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0019 | 0.0008 | 0.001 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0097 | 0.0505 | 0.995 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0097 | 0.0505 | 0.0872 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0172 | 0.0294 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0264 | 0.0454 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0019 | 0.0008 | 0.001 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0038 | 0.0061 |
Trypanosoma brucei | Alpha/beta hydrolase domain-containing protein | 0.0097 | 0.0505 | 0.0872 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0097 | 0.0507 | 1 |
Leishmania major | oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein | 0.0367 | 0.2226 | 0.3858 |
Plasmodium falciparum | plasmepsin III | 0.0019 | 0.0008 | 0.0156 |
Plasmodium vivax | hypothetical protein, conserved | 0.0097 | 0.0505 | 1 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0367 | 0.2226 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0038 | 0.0073 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0097 | 0.0505 | 1 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0097 | 0.0505 | 0.0872 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0097 | 0.0507 | 0.0505 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0038 | 0.0073 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0097 | 0.0505 | 0.0876 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0367 | 0.2226 | 1 |
Trypanosoma brucei | serine peptidase, clan SC, family S9A-like protein | 0.0367 | 0.2226 | 0.3858 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0097 | 0.0505 | 0.995 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0008 | 0.001 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0923 | 0.5765 | 1 |
Plasmodium falciparum | plasmepsin VI | 0.0019 | 0.0008 | 0.0156 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0019 | 0.0008 | 0.0014 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0038 | 0.0169 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0038 | 0.0169 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0025 | 0.0045 | 0.0074 |
Echinococcus granulosus | prolyl endopeptidase | 0.0923 | 0.5765 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0097 | 0.0505 | 0.0863 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0097 | 0.0505 | 0.995 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0097 | 0.0505 | 0.0872 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0025 | 0.0045 | 0.0074 |
Toxoplasma gondii | hypothetical protein | 0.0097 | 0.0505 | 0.0872 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0019 | 0.0008 | 0.001 |
Onchocerca volvulus | 0.0023 | 0.0038 | 0.0052 | |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0097 | 0.0505 | 0.0503 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0097 | 0.0505 | 0.0872 |
Echinococcus granulosus | serine protein kinase ATM | 0.0025 | 0.0045 | 0.0074 |
Plasmodium falciparum | plasmepsin VII | 0.0019 | 0.0008 | 0.0156 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0121 | 0.0656 | 0.1135 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0172 | 0.0294 |
Toxoplasma gondii | FATC domain-containing protein | 0.0025 | 0.0045 | 0.0074 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0019 | 0.0008 | 0.001 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.0161 | 0.0917 | 0.159 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.0154 | 0.0152 |
Plasmodium falciparum | peptidase, putative | 0.0097 | 0.0505 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0154 | 0.3022 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0214 | 0.0371 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0097 | 0.0505 | 0.0872 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0019 | 0.0008 | 0.0156 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0019 | 0.0008 | 0.001 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0097 | 0.0505 | 1 |
Plasmodium vivax | aspartyl protease, putative | 0.0019 | 0.0008 | 0.0156 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0172 | 0.0294 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0097 | 0.0505 | 0.995 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0097 | 0.0505 | 0.0872 |
Loa Loa (eye worm) | hypothetical protein | 0.0923 | 0.5765 | 1 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0097 | 0.0505 | 0.995 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0264 | 0.1187 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0923 | 0.5765 | 0.5764 |
Mycobacterium tuberculosis | Probable peptidase | 0.0367 | 0.2226 | 0.4323 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0099 | 0.0517 | 0.0893 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0264 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0505 | 0.0876 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0097 | 0.0505 | 1 |
Brugia malayi | Pepsin A precursor | 0.0019 | 0.0008 | 0.001 |
Plasmodium falciparum | plasmepsin II | 0.0019 | 0.0008 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.078 | 0.1353 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0334 | 0.0579 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0021 | 0.0023 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0145 | 0.0247 |
Trypanosoma brucei | prolyl endopeptidase | 0.0923 | 0.5765 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0923 | 0.5765 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.0923 | 0.5765 | 1 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0097 | 0.0505 | 0.0876 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0019 | 0.0008 | 0.0006 |
Plasmodium falciparum | plasmepsin IV | 0.0019 | 0.0008 | 0.0156 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0367 | 0.2226 | 0.3858 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0145 | 0.0247 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0038 | 0.0169 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0172 | 0.0294 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0923 | 0.5765 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0264 | 0.0454 |
Plasmodium vivax | aspartyl protease, putative | 0.0019 | 0.0008 | 0.0156 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0019 | 0.0008 | 0.0156 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0097 | 0.0505 | 0.0872 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0019 | 0.0008 | 0.001 |
Toxoplasma gondii | aspartyl protease | 0.0019 | 0.0008 | 0.001 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0367 | 0.2226 | 0.3858 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0019 | 0.0008 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0145 | 0.0247 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0019 | 0.0008 | 0.001 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0045 | 0.0841 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0019 | 0.0008 | 0.001 |
Plasmodium vivax | aspartyl protease, putative | 0.0019 | 0.0008 | 0.0156 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0097 | 0.0505 | 0.0872 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0097 | 0.0505 | 0.0872 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0038 | 0.0169 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0264 | 0.0454 |
Plasmodium falciparum | plasmepsin V | 0.0019 | 0.0008 | 0.0156 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0367 | 0.2226 | 0.4323 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0019 | 0.0008 | 0.0156 |
Trypanosoma cruzi | oligopeptidase b | 0.0367 | 0.2226 | 0.3858 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0038 | 0.0065 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0019 | 0.0008 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.1548 | 0.2685 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0923 | 0.5765 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Damage score (functional) | = 1.06 | Tested for its effect on hippocampal neuronal damage in gerbils activity | ChEMBL. | 2170646 |
Damage score (functional) | < 1.14 | Tested for its effect on Hypoxia induced neuronal damage | ChEMBL. | 2170646 |
IC50 (functional) | = 270 nM | Inhibitory concentration of the compound for [3H]-PCP binding to rat brain homogenate relative to PCP | ChEMBL. | 7310819 |
Relative potency (functional) | = 1 | Ability of the compound to displace 7.0 nM [3H]-PCP binding to rat brain homogenate relative to PCP (IC50= 270 nM) | ChEMBL. | 7310819 |
Relative potency (functional) | = 1 | Relative potency of the compound was determined in the rat discriminative stimulus assay, expressed as mg of PCP (= 1.0 mg of compound) | ChEMBL. | 7310819 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.