Detailed information for compound 562317

Basic information

Technical information
  • TDR Targets ID: 562317
  • Name: 2-(aminomethyl)-4-tert-butyl-6-iodo-phenol hy drochloride
  • MW: 341.616 | Formula: C11H17ClINO
  • H donors: 2 H acceptors: 1 LogP: 4.1 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCc1cc(cc(c1O)I)C(C)(C)C.Cl
  • InChi: 1S/C11H16INO.ClH/c1-11(2,3)8-4-7(6-13)10(14)9(12)5-8;/h4-5,14H,6,13H2,1-3H3;1H
  • InChiKey: HJCYVBBGVRHXKR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(aminomethyl)-4-tert-butyl-6-iodophenol hydrochloride

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Loa Loa (eye worm) ACC-1 protein 0.0082 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0082 0.0123 0.0123
Loa Loa (eye worm) tubulin alpha 2 0.012 0.2491 0.2491
Plasmodium falciparum alpha tubulin 1 0.0174 0.59 0.4682
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0082 0.0123 0.0123
Brugia malayi Cytochrome P450 family protein 0.0138 0.367 0.367
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0082 0.0123 0.0123
Echinococcus granulosus tubulin alpha 1C chain 0.0174 0.59 0.59
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0082 0.0123 0.0123
Giardia lamblia Beta tubulin 0.023 0.9432 1
Echinococcus granulosus beta tubulin 0.023 0.9432 0.9432
Brugia malayi Tubulin alpha-2 chain 0.0174 0.59 0.59
Plasmodium falciparum alpha tubulin 2 0.0174 0.59 0.4682
Echinococcus granulosus Tubulin alpha 1 chain 0.0174 0.59 0.59
Echinococcus multilocularis Tubulin alpha 1 chain 0.0174 0.59 0.59
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0082 0.0123 0.0123
Schistosoma mansoni nAChR subunit 0.0082 0.0123 0.0123
Trypanosoma cruzi cytochrome P450, putative 0.0138 0.367 0.3319
Leishmania major beta tubulin 0.023 0.9432 1
Brugia malayi Cation transporter family protein 0.0082 0.0123 0.0123
Trypanosoma brucei beta tubulin 0.023 0.9432 1
Onchocerca volvulus Putative nachr subunit 0.0082 0.0123 0.0564
Echinococcus multilocularis tubulin, beta 4A class IVa 0.023 0.9432 0.9432
Loa Loa (eye worm) tubulin gamma chain 0.0124 0.2791 0.2791
Loa Loa (eye worm) CYP4Cod1 0.0138 0.367 0.367
Brugia malayi Tubulin gamma chain 0.0124 0.2791 0.2791
Brugia malayi tubulin alpha-2 chain 0.0174 0.59 0.59
Loa Loa (eye worm) BEN-1 protein 0.023 0.9432 0.9432
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Echinococcus granulosus Tubulin beta 2C chain 0.023 0.9432 0.9432
Trypanosoma brucei beta tubulin 0.0124 0.2791 0.23
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0123 0.0123
Echinococcus granulosus glycine receptor subunit beta 0.0082 0.0123 0.0123
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0082 0.0123 0.0123
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0082 0.0123 0.0123
Loa Loa (eye worm) alpha-tubulin 0.0174 0.59 0.59
Echinococcus granulosus beta tubulin 0.023 0.9432 0.9432
Brugia malayi alpha-tubulin 0.0174 0.59 0.59
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0239 1 1
Echinococcus granulosus tubulin alpha 0.0124 0.2791 0.2791
Echinococcus granulosus tubulin gamma 1 chain 0.0124 0.2791 0.2791
Onchocerca volvulus 0.0082 0.0123 0.0564
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Brugia malayi tubulin alpha chain - mouse 0.0174 0.59 0.59
Trichomonas vaginalis tubulin gamma chain, putative 0.0124 0.2791 0.1672
Loa Loa (eye worm) hypothetical protein 0.0103 0.1458 0.1458
Leishmania major beta tubulin 0.023 0.9432 1
Loa Loa (eye worm) hypothetical protein 0.012 0.2491 0.2491
Giardia lamblia Beta tubulin 0.023 0.9432 1
Brugia malayi excitatory GABA receptor EXP-1A 0.0082 0.0123 0.0123
Loa Loa (eye worm) tubulin alpha-3 chain 0.0103 0.1458 0.1458
Loa Loa (eye worm) ACC-1 protein 0.0082 0.0123 0.0123
Echinococcus granulosus caspase 2 0.0115 0.2174 0.2174
Leishmania major cytochrome p450-like protein 0.0138 0.367 0.1323
Trichomonas vaginalis tubulin alpha chain, putative 0.023 0.9432 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Giardia lamblia Alpha-tubulin 0.0174 0.59 0.4682
Trypanosoma brucei beta tubulin 0.023 0.9432 1
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0082 0.0123 0.0123
Schistosoma mansoni tubulin subunit beta 0.023 0.9432 0.9432
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0082 0.0123 0.0123
Leishmania major beta tubulin 0.023 0.9432 1
Echinococcus multilocularis tubulin subunit beta 0.023 0.9432 0.9432
Trichomonas vaginalis tubulin epsilon chain, putative 0.023 0.9432 1
Trypanosoma cruzi epsilon tubulin, putative 0.0124 0.2791 0.23
Echinococcus multilocularis peroxisome assembly protein 26 0.0174 0.59 0.59
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0082 0.0123 0.0123
Echinococcus multilocularis tubulin alpha chain 0.0174 0.59 0.59
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0082 0.0123 0.0123
Plasmodium vivax tubulin beta chain, putative 0.023 0.9432 1
Loa Loa (eye worm) tubulin beta chain 0.023 0.9432 0.9432
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0082 0.0123 0.0123
Echinococcus granulosus tubulin subunit TubB 0.0174 0.59 0.59
Echinococcus multilocularis Tubulin beta 2C chain 0.023 0.9432 0.9432
Schistosoma mansoni nAChR subunit 0.0082 0.0123 0.0123
Loa Loa (eye worm) tubulin beta-4 chain 0.023 0.9432 0.9432
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0082 0.0123 0.0123
Brugia malayi Tubulin beta-1 chain 0.023 0.9432 0.9432
Schistosoma mansoni tubulin subunit alpha 0.0174 0.59 0.59
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0082 0.0123 0.0123
Entamoeba histolytica tubulin family protein 0.023 0.9432 1
Trypanosoma brucei alpha tubulin 0.0174 0.59 0.5905
Giardia lamblia Beta tubulin 0.023 0.9432 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Echinococcus granulosus tubulin epsilon chain 0.0124 0.2791 0.2791
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0082 0.0123 0.0123
Echinococcus multilocularis tubulin epsilon chain 0.0124 0.2791 0.2791
Echinococcus multilocularis tubulin gamma 1 chain 0.0124 0.2791 0.2791
Loa Loa (eye worm) alpha-tubulin isotype 2 0.012 0.2491 0.2491
Echinococcus granulosus Tubulin beta 2C chain 0.023 0.9432 0.9432
Echinococcus granulosus gamma secretase subunit aph 1 0.0239 1 1
Echinococcus multilocularis Tubulin beta 2C chain 0.023 0.9432 0.9432
Brugia malayi Cytochrome P450 family protein 0.0138 0.367 0.367
Leishmania major beta tubulin 0.023 0.9432 1
Trypanosoma brucei alpha tubulin 0.0174 0.59 0.5905
Trichomonas vaginalis tubulin epsilon chain, putative 0.0174 0.59 0.5571
Echinococcus multilocularis hypothetical protein 0.0174 0.59 0.59
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0082 0.0123 0.0123
Echinococcus multilocularis tubulin alpha chain 0.0174 0.59 0.59
Loa Loa (eye worm) tubulin alpha-2 chain 0.0174 0.59 0.59
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0082 0.0123 0.0123
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0082 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Schistosoma mansoni nAChR subunit 0.0082 0.0123 0.0123
Toxoplasma gondii alpha tubulin TUBA1 0.0174 0.59 0.4682
Echinococcus multilocularis tubulin alpha 0.0124 0.2791 0.2791
Echinococcus granulosus alpha tubulin 0.0174 0.59 0.59
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.0123 0.0123
Echinococcus multilocularis glycine receptor subunit beta 0.0082 0.0123 0.0123
Schistosoma mansoni alpha tubulin 0.0174 0.59 0.59
Echinococcus multilocularis Tubulin beta 2C chain 0.023 0.9432 0.9432
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0082 0.0123 0.0123
Echinococcus multilocularis Tubulin alpha 1 chain 0.0174 0.59 0.59
Trypanosoma brucei epsilon tubulin 0.0124 0.2791 0.23
Loa Loa (eye worm) hypothetical protein 0.0115 0.2174 0.2174
Onchocerca volvulus Cell death protein 3 homolog 0.0115 0.2174 1
Echinococcus multilocularis tubulin subunit TubB 0.0174 0.59 0.59
Loa Loa (eye worm) LGC-31 protein 0.0082 0.0123 0.0123
Trichomonas vaginalis tubulin beta chain, putative 0.0174 0.59 0.5571
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Echinococcus multilocularis beta tubulin 0.023 0.9432 0.9432
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0082 0.0123 0.0123
Toxoplasma gondii beta-1 tubulin, putative 0.023 0.9432 1
Echinococcus multilocularis tubulin alpha 1C chain 0.0174 0.59 0.59
Echinococcus granulosus tubulin beta 1 chain 0.023 0.9432 0.9432
Schistosoma mansoni nAChR subunit 0.0082 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Echinococcus granulosus tubulin alpha chain 0.0174 0.59 0.59
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0082 0.0123 0.0123
Toxoplasma gondii beta-tubulin, putative 0.023 0.9432 1
Echinococcus multilocularis beta tubulin 0.023 0.9432 0.9432
Echinococcus granulosus Tubulin beta 2C chain 0.023 0.9432 0.9432
Entamoeba histolytica tubulin alpha-1 chain 0.0174 0.59 0.4682
Echinococcus granulosus Tubulin alpha 1 chain 0.0174 0.59 0.59
Loa Loa (eye worm) alpha-tubulin 0.0174 0.59 0.59
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0082 0.0123 0.0123
Schistosoma mansoni tubulin subunit beta 0.023 0.9432 0.9432
Brugia malayi Cation transporter family protein 0.0082 0.0123 0.0123
Loa Loa (eye worm) cytochrome P450 family protein 0.0138 0.367 0.367
Trypanosoma cruzi tubulin gamma chain 0.0124 0.2791 0.23
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0174 0.59 0.5571
Echinococcus granulosus tubulin alpha 3 chain 0.0174 0.59 0.59
Echinococcus multilocularis glycine receptor subunit beta 0.0082 0.0123 0.0123
Leishmania major beta tubulin 0.023 0.9432 1
Leishmania major beta tubulin 0.023 0.9432 1
Onchocerca volvulus 0.0082 0.0123 0.0564
Brugia malayi Cell death protein 3 precursor 0.0115 0.2174 0.2174
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0123 0.0123
Trypanosoma cruzi epsilon tubulin, putative 0.0124 0.2791 0.23
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Echinococcus multilocularis nAChR subunit 0.0082 0.0123 0.0123
Echinococcus granulosus glycine receptor subunit beta 0.0082 0.0123 0.0123
Echinococcus multilocularis Tubulin beta 2C chain 0.023 0.9432 0.9432
Giardia lamblia Alpha-tubulin 0.0174 0.59 0.4682
Echinococcus granulosus peroxisome assembly protein 26 0.0174 0.59 0.59
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.0123 0.0123
Echinococcus granulosus Tubulin beta 2C chain 0.023 0.9432 0.9432
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0123 0.0123
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.0123 0.0123
Trichomonas vaginalis tubulin beta chain, putative 0.023 0.9432 1
Loa Loa (eye worm) tubulin alpha chain 0.0174 0.59 0.59
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0082 0.0123 0.0123
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0082 0.0123 0.0123
Trichomonas vaginalis tubulin epsilon chain, putative 0.0174 0.59 0.5571
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0082 0.0123 0.0123
Leishmania major beta tubulin 0.023 0.9432 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0082 0.0123 0.0123
Trypanosoma brucei epsilon tubulin 0.0124 0.2791 0.23
Loa Loa (eye worm) hypothetical protein 0.0099 0.1158 0.1158
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0082 0.0123 0.0123
Entamoeba histolytica tubulin family protein 0.023 0.9432 1
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Brugia malayi Cation transporter family protein 0.0082 0.0123 0.0123
Echinococcus granulosus glycine receptor subunit alpha 1 0.0082 0.0123 0.0123
Echinococcus multilocularis caspase 2 0.0115 0.2174 0.2174
Schistosoma mansoni gamma-secretase subunit aph-1 0.0239 1 1
Onchocerca volvulus 0.0082 0.0123 0.0564
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0123 0.0123
Trypanosoma brucei beta tubulin 0.023 0.9432 1
Toxoplasma gondii beta tubulin 0.023 0.9432 1
Trichomonas vaginalis tubulin beta chain, putative 0.0174 0.59 0.5571
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Trypanosoma brucei alpha tubulin 0.0174 0.59 0.5905
Onchocerca volvulus 0.0082 0.0123 0.0564
Trypanosoma cruzi cytochrome P450, putative 0.0138 0.367 0.3319
Leishmania major beta tubulin 0.023 0.9432 1
Trypanosoma brucei beta tubulin 0.023 0.9432 1
Leishmania major beta tubulin 0.023 0.9432 1
Trypanosoma brucei alpha tubulin 0.0174 0.59 0.5905
Echinococcus granulosus tubulin alpha chain 0.0174 0.59 0.59
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Loa Loa (eye worm) tubulin alpha 2 0.012 0.2491 0.2491
Loa Loa (eye worm) tubulin alpha chain 0.0174 0.59 0.59
Echinococcus granulosus tubulin alpha 1C chain 0.0174 0.59 0.59
Loa Loa (eye worm) hypothetical protein 0.0174 0.59 0.59
Schistosoma mansoni tubulin subunit beta 0.023 0.9432 0.9432
Echinococcus granulosus tubulin alpha 3 chain 0.0174 0.59 0.59
Echinococcus granulosus tubulin alpha chain 0.0174 0.59 0.59
Trichomonas vaginalis tubulin beta chain, putative 0.0174 0.59 0.5571
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0082 0.0123 0.0123
Schistosoma mansoni tubulin subunit beta 0.023 0.9432 0.9432
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Echinococcus multilocularis tubulin alpha chain 0.0174 0.59 0.59
Loa Loa (eye worm) tubulin beta-2A chain 0.023 0.9432 0.9432
Leishmania major beta tubulin 0.023 0.9432 1
Brugia malayi beta-tubulin, identical 0.023 0.9432 0.9432
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0082 0.0123 0.0123
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.012 0.2491 0.1296
Echinococcus multilocularis Tubulin beta 2C chain 0.023 0.9432 0.9432
Echinococcus multilocularis tubulin alpha chain 0.0174 0.59 0.59
Brugia malayi Tubulin alpha chain 0.0174 0.59 0.59
Trichomonas vaginalis tubulin, putative 0.023 0.9432 1
Loa Loa (eye worm) BEN-1 protein 0.023 0.9432 0.9432
Echinococcus granulosus nAChR subunit 0.0082 0.0123 0.0123
Schistosoma mansoni caspase-7 (C14 family) 0.0115 0.2174 0.2174
Schistosoma mansoni nAChR subunit 0.0082 0.0123 0.0123
Schistosoma mansoni tubulin subunit epsilon 0.0124 0.2791 0.2791
Loa Loa (eye worm) beta-tubulin 0.023 0.9432 0.9432
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Echinococcus multilocularis gamma secretase subunit aph 1 0.0239 1 1
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0082 0.0123 0.0123
Schistosoma mansoni tubulin subunit beta 0.023 0.9432 0.9432
Toxoplasma gondii alpha-tubulin I, putative 0.0174 0.59 0.4682
Schistosoma mansoni tubulin subunit gamma 0.0124 0.2791 0.2791
Trichomonas vaginalis tubulin epsilon chain, putative 0.023 0.9432 1
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Plasmodium vivax tubulin alpha chain, putative 0.0174 0.59 0.4682
Onchocerca volvulus 0.0082 0.0123 0.0564
Echinococcus granulosus tubulin alpha chain 0.0174 0.59 0.59
Trypanosoma brucei tubulin gamma chain 0.0124 0.2791 0.23
Leishmania major beta tubulin 0.023 0.9432 1
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0082 0.0123 0.0123
Echinococcus multilocularis tubulin alpha 1C chain 0.0174 0.59 0.59
Echinococcus granulosus Tubulin alpha 1 chain 0.0174 0.59 0.59
Leishmania major beta tubulin 0.023 0.9432 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0082 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Schistosoma mansoni nAChR subunit 0.0082 0.0123 0.0123
Schistosoma mansoni tubulin subunit alpha 0.0174 0.59 0.59
Loa Loa (eye worm) cytochrome P450 family protein 0.0138 0.367 0.367
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0082 0.0123 0.0123
Leishmania major beta tubulin 0.023 0.9432 1
Schistosoma mansoni alpha tubulin 0.0174 0.59 0.59
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Trichomonas vaginalis tubulin beta chain, putative 0.0174 0.59 0.5571
Leishmania major beta tubulin 0.023 0.9432 1
Brugia malayi Tubulin alpha-2 chain 0.0174 0.59 0.59
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0138 0.367 0.5
Echinococcus granulosus Tubulin beta 2C chain 0.023 0.9432 0.9432
Leishmania major beta tubulin 0.023 0.9432 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Plasmodium falciparum tubulin beta chain 0.023 0.9432 1
Schistosoma mansoni alpha tubulin 0.0174 0.59 0.59
Leishmania major beta tubulin 0.023 0.9432 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0123 0.0123
Echinococcus multilocularis tubulin alpha chain 0.0174 0.59 0.59
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0082 0.0123 0.0123
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Onchocerca volvulus 0.0082 0.0123 0.0564
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0082 0.0123 0.0123
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0123 0.0123
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0082 0.0123 0.0123
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0082 0.0123 0.0123
Trypanosoma brucei epsilon tubulin 0.0124 0.2791 0.23
Schistosoma mansoni tubulin subunit alpha 0.0174 0.59 0.59
Trichomonas vaginalis tubulin beta chain, putative 0.0174 0.59 0.5571
Echinococcus multilocularis tubulin beta 1 chain 0.023 0.9432 0.9432
Trichomonas vaginalis tubulin gamma chain, putative 0.023 0.9432 1
Leishmania major beta tubulin 0.023 0.9432 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0124 0.2791 0.1672
Leishmania major alpha tubulin 0.0174 0.59 0.4682
Trichomonas vaginalis tubulin beta chain, putative 0.0174 0.59 0.5571
Entamoeba histolytica tubulin alpha chain, putative 0.0174 0.59 0.4682
Trypanosoma cruzi beta tubulin, putative 0.023 0.9432 1
Loa Loa (eye worm) tubulin beta-1 chain 0.023 0.9432 0.9432
Trypanosoma brucei cytochrome P450, putative 0.0138 0.367 0.3319
Trypanosoma cruzi alpha tubulin, putative 0.0174 0.59 0.5905
Echinococcus multilocularis tubulin alpha 3 chain 0.0174 0.59 0.59
Echinococcus granulosus tubulin beta 4A class IVa 0.023 0.9432 0.9432
Echinococcus multilocularis tubulin alpha 3 chain 0.0174 0.59 0.59
Plasmodium vivax tubulin alpha chain, putative 0.0174 0.59 0.4682
Leishmania major beta tubulin 0.023 0.9432 1
Schistosoma mansoni nAChR subunit 0.0082 0.0123 0.0123
Echinococcus granulosus tubulin subunit beta 0.023 0.9432 0.9432
Echinococcus granulosus tubulin alpha chain 0.0174 0.59 0.59
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0123 0.0123
Trichomonas vaginalis tubulin gamma chain, putative 0.0124 0.2791 0.1672
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0082 0.0123 0.0123
Echinococcus multilocularis Tubulin alpha 1 chain 0.0174 0.59 0.59
Schistosoma mansoni tubulin subunit beta 0.023 0.9432 0.9432
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0082 0.0123 0.0123

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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