Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glutathione S transferase | 0.0103 | 0.075 | 0.4467 |
Mycobacterium ulcerans | hypothetical protein | 0.0182 | 0.1765 | 1 |
Echinococcus multilocularis | glutathione S transferase | 0.014 | 0.1221 | 1 |
Onchocerca volvulus | Lactoylglutathione lyase homolog | 0.0787 | 0.9548 | 1 |
Mycobacterium tuberculosis | Conserved protein TB27.3 | 0.0182 | 0.1765 | 1 |
Echinococcus multilocularis | glutathione S transferase | 0.014 | 0.1221 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0182 | 0.1765 | 1 |
Schistosoma mansoni | glutathione-S-transferase | 0.014 | 0.1221 | 0.6097 |
Mycobacterium ulcerans | glyoxalase GloA | 0.0182 | 0.1765 | 1 |
Echinococcus granulosus | glutathione s transferase mu | 0.014 | 0.1221 | 0.1492 |
Plasmodium falciparum | glyoxalase I | 0.0182 | 0.1765 | 0.152 |
Echinococcus multilocularis | glutathione S transferase | 0.0103 | 0.075 | 0.4467 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0182 | 0.1765 | 1 |
Mycobacterium tuberculosis | Cadmium inducible protein CadI | 0.0182 | 0.1765 | 1 |
Echinococcus granulosus | glutathione S transferase | 0.0103 | 0.075 | 0.0666 |
Schistosoma mansoni | 4-hydroxyphenylpyruvate dioxygenase | 0.0182 | 0.1765 | 1 |
Onchocerca volvulus | Putative protein | 0.0182 | 0.1765 | 0.1727 |
Brugia malayi | lactoylglutathione lyase | 0.0787 | 0.9548 | 0.9531 |
Schistosoma mansoni | gynecophoral canal protein | 0.0182 | 0.1765 | 1 |
Onchocerca volvulus | 0.0103 | 0.075 | 0.0648 | |
Mycobacterium ulcerans | hypothetical protein | 0.0182 | 0.1765 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0182 | 0.1765 | 1 |
Echinococcus multilocularis | glutathione s transferase mu | 0.014 | 0.1221 | 1 |
Brugia malayi | 4-hydroxyphenylpyruvate dioxygenase family protein | 0.0182 | 0.1765 | 0.1448 |
Trichomonas vaginalis | glutaminyl-tRNA synthetase, putative | 0.0103 | 0.075 | 0.2723 |
Mycobacterium ulcerans | biphenyl-2,3-diol 1,2-dioxygenase | 0.0182 | 0.1765 | 1 |
Loa Loa (eye worm) | 4-hydroxyphenylpyruvate dioxygenase | 0.0182 | 0.1765 | 0.1448 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.9548 | 0.9531 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0182 | 0.1765 | 1 |
Plasmodium vivax | glutathione S-transferase, putative | 0.014 | 0.1221 | 0.0926 |
Trypanosoma cruzi | lactoylglutathione lyase-like protein, putative | 0.0787 | 0.9548 | 1 |
Leishmania major | glyoxalase I,trypanothione-dependent glyoxalase I | 0.0787 | 0.9548 | 1 |
Plasmodium falciparum | glyoxalase I | 0.0787 | 0.9548 | 1 |
Brugia malayi | Glutathione S-transferase 4 | 0.0103 | 0.075 | 0.0394 |
Plasmodium vivax | glyoxalase I, putative | 0.0787 | 0.9548 | 1 |
Plasmodium falciparum | glutathione S-transferase | 0.014 | 0.1221 | 0.0926 |
Mycobacterium ulcerans | hypothetical protein | 0.0182 | 0.1765 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0182 | 0.1765 | 1 |
Echinococcus multilocularis | glutathione S transferase | 0.014 | 0.1221 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0182 | 0.1765 | 1 |
Toxoplasma gondii | glyoxalase family protein | 0.0182 | 0.1765 | 0.152 |
Mycobacterium ulcerans | hypothetical protein | 0.0182 | 0.1765 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.075 | 0.0394 |
Echinococcus multilocularis | prostaglandin H2 D isomerase | 0.014 | 0.1221 | 1 |
Toxoplasma gondii | glyoxalase I, putative | 0.0787 | 0.9548 | 1 |
Schistosoma mansoni | GST class-mu | 0.014 | 0.1221 | 0.6097 |
Loa Loa (eye worm) | hypothetical protein | 0.0822 | 1 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0182 | 0.1765 | 1 |
Trypanosoma brucei | hydroxyacylglutathione hydrolase, putative | 0.0074 | 0.037 | 0.5 |
Echinococcus multilocularis | glutathione S-transferase | 0.014 | 0.1221 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0182 | 0.1765 | 1 |
Echinococcus granulosus | glutathione S transferase | 0.014 | 0.1221 | 0.1492 |
Schistosoma mansoni | Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) | 0.014 | 0.1221 | 0.6097 |
Mycobacterium ulcerans | glyoxalase GloA | 0.0182 | 0.1765 | 1 |
Echinococcus granulosus | glutathione S transferase Mu 1 | 0.0517 | 0.6071 | 1 |
Trypanosoma cruzi | lactoylglutathione lyase-like protein, putative | 0.0787 | 0.9548 | 1 |
Echinococcus granulosus | prostaglandin H2 D isomerase | 0.014 | 0.1221 | 0.1492 |
Plasmodium vivax | glyoxalase I, putative | 0.0182 | 0.1765 | 0.152 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.