Detailed information for compound 578609

Basic information

Technical information
  • TDR Targets ID: 578609
  • Name: 2-(benzenesulfonyl)guanidine
  • MW: 199.23 | Formula: C7H9N3O2S
  • H donors: 2 H acceptors: 2 LogP: -0.03 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=NS(=O)(=O)c1ccccc1)N
  • InChi: 1S/C7H9N3O2S/c8-7(9)10-13(11,12)6-4-2-1-3-5-6/h1-5H,(H4,8,9,10)
  • InChiKey: BRSRNTJGTDYRFT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(phenylsulfonyl)guanidine
  • 2-besylguanidine
  • 2-phenylsulfonylguanidine
  • N-(Aminoiminomethyl)benzenesulphonamide
  • EINECS 224-512-0
  • AIDS-018489
  • AIDS018489
  • N-(Diamino-methylene)benzenesulfonamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.002 0.0132 0.0337
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.017 0.0196
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0086 0.0013
Onchocerca volvulus 0.0026 0.021 0.057
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0111 0.5
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0111 0.0234
Treponema pallidum hypothetical protein 0.0279 0.3353 1
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0132 0.0359
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0537 0.1457
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.021 0.057
Leishmania major GTP-binding protein, putative 0.0022 0.0161 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0132 0.0132
Echinococcus granulosus pyruvate kinase 0.0018 0.0107 0.0107
Loa Loa (eye worm) apoptosis regulator protein 0.0164 0.193 0.4921
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0279 0.3353 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0817
Trichomonas vaginalis dullard protein, putative 0.0012 0.0033 0.0484
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.032 0.0869
Brugia malayi nuclear hormone receptor 0.002 0.0132 0.0359
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0086 0.2232
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0132 0.0359
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Schistosoma mansoni importin beta-1 0.003 0.0261 0.0261
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0086 0.0233
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.002 0.0132 0.0337
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.004 0.004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0059 0.0059
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0132 0.0132
Mycobacterium tuberculosis Conserved hypothetical protein 0.0316 0.3817 1
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0187 0.5614
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0817
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0161 0.0436
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0324 0.3923 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0086 0.2232
Echinococcus granulosus pyruvate kinase 0.0035 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0089 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0817
Brugia malayi Cathepsin L-like precursor 0.0016 0.0086 0.0233
Echinococcus granulosus cathepsin l1 0.0016 0.0086 0.0086
Chlamydia trachomatis pyruvate kinase 0.0035 0.032 1
Schistosoma mansoni cpg binding protein 0.0057 0.0592 0.0592
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0132 0.0359
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0218
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0059 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0817
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0132 0.0132
Schistosoma mansoni nuclear hormone receptor 0.002 0.0132 0.0132
Onchocerca volvulus 0.002 0.0132 0.0359
Schistosoma mansoni apoptosis regulator bax 0.0164 0.193 0.193
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0812 1 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0086 0.0159
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0261 0.1905
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0187 0.0478
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0164 0.193 0.193
Brugia malayi Cathepsin L-like precursor 0.0016 0.0086 0.0233
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0059 0.0059
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0084 0.0933 0.1229
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0053 0.0537 0.1368
Schistosoma mansoni hypothetical protein 0.0017 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.002 0.0132 0.0337
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0161 0.041
Leishmania major cathepsin L-like protease 0.0062 0.0658 0.0854
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0438 0.0438
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0279 0.3353 1
Leishmania major cathepsin L-like protease 0.0016 0.0086 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0132 0.0337
Onchocerca volvulus 0.005 0.0504 0.1369
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0086 0.0218
Echinococcus granulosus FTZ F1 alpha 0.002 0.0132 0.0132
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0132 0.0337
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0132 0.0132
Schistosoma mansoni cpg binding protein 0.006 0.0633 0.0633
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0189 0.0213
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0132 0.0132
Leishmania major cathepsin L-like protease 0.0016 0.0086 0.0072
Entamoeba histolytica cysteine protease, putative 0.0016 0.0086 0.2235
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0161 0.0385
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0111 0.0111
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0014 0.0038
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0132 0.0132
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0086 0.2232
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0081 0.0065
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0592 0.151
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0132 0.0359
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0438 0.0438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0079
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0132 0.0132
Loa Loa (eye worm) pyruvate kinase 0.0035 0.032 0.0816
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0111 0.2711
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0111 0.3064
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0504 0.0504
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0132 0.0337
Loa Loa (eye worm) hypothetical protein 0.0023 0.017 0.0434
Brugia malayi ecdysteroid receptor 0.002 0.0132 0.0359
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0036
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0081 0.0081
Schistosoma mansoni intermediate filament proteins 0.0026 0.021 0.021
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0081 0.0144
Echinococcus multilocularis snurportin 1 0.0324 0.3923 0.3923
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0014 0.0014
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0012 0.0033 0.0484
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0089 0.0089
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0086 0.0086
Echinococcus granulosus cpg binding protein 0.006 0.0633 0.0633
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.004 0.004
Toxoplasma gondii cathepsin CPL 0.0016 0.0086 0.0441
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0132 0.0132
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0111 0.0234
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0107 0.0618
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0132 0.0132
Echinococcus granulosus GPCR family 2 0.0017 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.002 0.0132 0.0337
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0102 0.0102
Brugia malayi hypothetical protein 0.0305 0.3682 1
Brugia malayi AMP-binding enzyme family protein 0.0023 0.017 0.0463
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0086 0.0233
Loa Loa (eye worm) hypothetical protein 0.0026 0.0204 0.052
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0329 0.0895
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0084 0.0933 0.1229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0249
Echinococcus granulosus snurportin 1 0.0324 0.3923 0.3923
Toxoplasma gondii hypothetical protein 0.0097 0.1087 0.882
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0161 0.1069
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.0059 0.0059
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0102 0.026
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0438 0.1117
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0817
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0132 0.0132
Brugia malayi Cathepsin L-like precursor 0.0016 0.0086 0.0233
Brugia malayi AMP-binding enzyme family protein 0.0023 0.017 0.0463
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0132 0.0359
Brugia malayi RNA, U transporter 1 0.0086 0.0959 0.2603
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0132 0.0359
Loa Loa (eye worm) hypothetical protein 0.0023 0.017 0.0434
Brugia malayi cathepsin L-like precursor 0.0011 0.0018 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0817
Entamoeba histolytica hypothetical protein 0.0035 0.032 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0132 0.0132
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0086 0.2232
Loa Loa (eye worm) hypothetical protein 0.0035 0.032 0.0816
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0164 0.193 0.193
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0791 0.9744 0.9744
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0132 0.0359
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0086 0.2232
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.032 0.0869
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Echinococcus granulosus cathepsin l1 0.0011 0.0018 0.0018
Mycobacterium ulcerans pyruvate kinase 0.0035 0.032 0.0598
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0438 0.0438
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0132 0.0132
Trypanosoma brucei mitochondrial DNA polymerase beta 0.06 0.7353 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0438 0.0438
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0098 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0817
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0081 0.0081
Schistosoma mansoni hypothetical protein 0.0324 0.3923 0.3923
Echinococcus multilocularis cysteine protease 0.0016 0.0086 0.0086
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0098 0.0194
Loa Loa (eye worm) hypothetical protein 0.003 0.0261 0.0664
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0817
Loa Loa (eye worm) ctsf protein 0.0016 0.0086 0.0218
Trichomonas vaginalis helicase, putative 0.0013 0.0043 0.0817
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0284 0.3418 0.4624
Echinococcus multilocularis pyruvate kinase 0.0028 0.0228 0.0228
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0279 0.3353 0.8757
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0089 0.0242
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0018 0.005
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0086 0.0072
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0086 0.0218
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0111 0.3064
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0086 0.0013
Onchocerca volvulus 0.0016 0.0086 0.0233
Onchocerca volvulus 0.0057 0.0592 0.1609
Echinococcus granulosus intermediate filament protein 0.0026 0.021 0.021
Echinococcus multilocularis pyruvate kinase 0.0018 0.0107 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0132 0.0337
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0086 0.0086
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.017 0.0188
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0111 0.0106
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0537 0.1457
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0438 0.1191
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0086 0.0159
Schistosoma mansoni hypothetical protein 0.0164 0.193 0.193
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0086 0.2235
Onchocerca volvulus 0.0016 0.0086 0.0233
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0036
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0012 0.0033 0.0484
Entamoeba histolytica hypothetical protein 0.0035 0.032 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0086 0.2232
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0086 0.0013
Trichomonas vaginalis dullard protein, putative 0.0012 0.0033 0.0484
Schistosoma mansoni hypothetical protein 0.0012 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0132 0.0337
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0132 0.0132
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0161 0.0174
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0043 0.0817
Loa Loa (eye worm) hypothetical protein 0.0023 0.017 0.0434
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0012 0.0033 0.0033
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0132 0.0359
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0086 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0132 0.0359
Trichomonas vaginalis dullard protein, putative 0.0012 0.0033 0.0484
Schistosoma mansoni hypothetical protein 0.0164 0.193 0.193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Echinococcus multilocularis pyruvate kinase 0.0018 0.0107 0.0107
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0012 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0036
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.017 0.0196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Onchocerca volvulus 0.0016 0.0086 0.0233
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0011 0.0015 0.004
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.032 0.2402
Brugia malayi AMP-binding enzyme family protein 0.0023 0.017 0.0463
Entamoeba histolytica hypothetical protein 0.0025 0.0189 0.5664
Brugia malayi intermediate filament protein 0.0026 0.021 0.057
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0012 0.0033 0.0484
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.032 1
Mycobacterium ulcerans hypothetical protein 0.0316 0.3817 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0086 0.0159
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0164 0.193 0.193
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0086 0.2235
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0043 0.0817
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0081 0.0065
Echinococcus multilocularis tumor protein p63 0.0341 0.4131 0.4131
Loa Loa (eye worm) hypothetical protein 0.0026 0.021 0.0535
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0132 0.0132
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0261 0.0311
Brugia malayi Cathepsin L-like precursor 0.0011 0.0018 0.005
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0086 0.0086
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0132 0.0132
Echinococcus multilocularis dnaJ subfamily B 0.0812 1 1
Brugia malayi steroid hormone receptor 0.002 0.0132 0.0359
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0132 0.0132
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.032 0.047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.017 0.024
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0014 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0817
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0081 0.0065
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0132 0.0132
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0132 0.0337
Leishmania major cathepsin L-like protease 0.0016 0.0086 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Echinococcus granulosus geminin 0.0336 0.4074 0.4074
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0164 0.193 0.193
Leishmania major importin beta-1 subunit, putative 0.0025 0.0189 0.0213
Trichomonas vaginalis ran, putative 0.0022 0.0161 0.4717
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0081 0.04
Toxoplasma gondii exonuclease III APE 0.0018 0.0111 0.0651
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0132 0.0337
Schistosoma mansoni hypothetical protein 0.0035 0.032 0.032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0817
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0012 0.0033 0.0033
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0132 0.0132
Echinococcus multilocularis importin subunit beta 1 0.003 0.0261 0.0261
Schistosoma mansoni hypothetical protein 0.0036 0.0329 0.0329
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0438 0.0438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Leishmania major cathepsin L-like protease 0.0016 0.0086 0.0072
Echinococcus granulosus lamin dm0 0.0026 0.021 0.021
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0817
Loa Loa (eye worm) hypothetical protein 0.0164 0.193 0.4921
Entamoeba histolytica hypothetical protein 0.0035 0.032 1
Schistosoma mansoni pyruvate kinase 0.0018 0.0107 0.0107
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0161 0.0385
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0189 0.5657
Schistosoma mansoni hypothetical protein 0.0017 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.0336 0.4074 0.4074
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.017 0.5047
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0132 0.0132
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0492 0.0627
Leishmania major cathepsin L-like protease 0.0062 0.0658 0.0854
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.032 0.0392
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0086 0.0072
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0111 0.3068
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0249
Schistosoma mansoni thyroid hormone receptor 0.002 0.0132 0.0132
Entamoeba histolytica Ran family GTPase 0.0022 0.0161 0.4723
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0161 0.0174
Schistosoma mansoni hypothetical protein 0.0017 0.0089 0.0089
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.017 0.024
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0132 0.0359
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0132 0.0132
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0107 0.0223
Schistosoma mansoni thyroid hormone receptor 0.002 0.0132 0.0132
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0012 0.0033 0.009
Brugia malayi nuclear receptor NHR-88 0.002 0.0132 0.0359
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0047
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0081 0.0065
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0103 0.1162 0.1543
Brugia malayi F/Y-rich N-terminus family protein 0.0017 0.0099 0.0269
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Brugia malayi hypothetical protein 0.0011 0.0014 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0086 0.2232
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0132 0.0359
Leishmania major cathepsin L-like protease 0.0016 0.0086 0.0072
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0012 0.0033 0.0484
Echinococcus multilocularis cysteine protease 0.0016 0.0086 0.0086
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0012 0.0033 0.0084
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0261 0.0311
Loa Loa (eye worm) hypothetical protein 0.002 0.0132 0.0337
Echinococcus multilocularis lamin dm0 0.0026 0.021 0.021
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0111 0.0111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0086 0.2232
Echinococcus granulosus pyruvate kinase 0.0018 0.0107 0.0107
Plasmodium vivax pyruvate kinase, putative 0.0035 0.032 0.0865
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0933 0.1229
Brugia malayi nuclear receptor RXR 0.0011 0.0014 0.0038
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0161 0.4449
Schistosoma mansoni pyruvate kinase 0.0035 0.032 0.032
Onchocerca volvulus 0.0305 0.3682 1
Echinococcus granulosus lamin 0.0026 0.021 0.021
Echinococcus multilocularis GPCR, family 2 0.0017 0.0089 0.0089
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0658 0.0854
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0164 0.193 0.193
Loa Loa (eye worm) hypothetical protein 0.002 0.0132 0.0337
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.017 0.0196
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0089 0.0089
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0081 0.0206
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0107 0.0223
Plasmodium vivax importin-beta 2, putative 0.003 0.0261 0.0686
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0249
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0189 0.5657
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0111 0.0282
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0438 0.0438
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0086 0.0233
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.017 0.0188
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.1389 0.1389
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0187 0.0478
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Brugia malayi Cathepsin L-like precursor 0.0016 0.0086 0.0233
Loa Loa (eye worm) hypothetical protein 0.0013 0.004 0.0103
Onchocerca volvulus 0.0026 0.021 0.057
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.017 0.0196
Leishmania major mitochondrial DNA polymerase beta 0.06 0.7353 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0081 0.0081
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0537 0.1368
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.032 0.0869
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0111 0.0106
Brugia malayi Cathepsin L-like precursor 0.0016 0.0086 0.0233
Leishmania major pyruvate kinase 0.0035 0.032 0.0392
Schistosoma mansoni pyruvate kinase 0.0035 0.032 0.032
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0132 0.0132
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0111 0.0106
Leishmania major cathepsin L-like protease 0.0062 0.0658 0.0854
Echinococcus granulosus tumor protein p63 0.0341 0.4131 0.4131
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0088
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0132 0.0359
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0132 0.0337
Brugia malayi CXXC zinc finger family protein 0.0057 0.0592 0.1609
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0086 0.2232
Schistosoma mansoni hypothetical protein 0.0017 0.0089 0.0089
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0081 0.0081
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0081 0.0081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0817
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0249
Echinococcus multilocularis cpg binding protein 0.006 0.0633 0.0633
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0086 0.2232
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0132 0.0359
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0132 0.0359
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0438 0.0438
Schistosoma mansoni ran 0.0022 0.0161 0.0161
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.06 0.7353 1
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.032 1
Echinococcus granulosus pyruvate kinase 0.0018 0.0107 0.0107
Echinococcus granulosus pyruvate kinase 0.0035 0.032 0.032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0132 0.0337
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0014 0.0038
Echinococcus multilocularis pyruvate kinase 0.0035 0.032 0.032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0086 0.0233
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.06 0.7353 1
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0081 0.04
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0089 0.0089
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0658 0.0854
Schistosoma mansoni hypothetical protein 0.0164 0.193 0.193
Loa Loa (eye worm) intermediate filament protein 0.0026 0.021 0.0535
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0086 0.2232
Leishmania major pyruvate kinase 0.0035 0.032 0.0392
Loa Loa (eye worm) fibroinase 0.0016 0.0086 0.0218
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0012 0.0033 0.0484
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0014 0.0014
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.032 0.064
Echinococcus granulosus importin subunit beta 1 0.003 0.0261 0.0261
Loa Loa (eye worm) cysteine protease 0.0016 0.0086 0.0218
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.017 0.5047
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0089 0.0242
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0933 0.1229
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0132 0.0359
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0591 0.0762
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0132 0.0359
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0081 0.0065
Loa Loa (eye worm) hypothetical protein 0.005 0.0504 0.1285
Loa Loa (eye worm) pyruvate kinase 0.0035 0.032 0.0816
Trypanosoma brucei pyruvate kinase 1 0.0035 0.032 0.0392
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.032 0.032
Schistosoma mansoni coup transcription factor 0.002 0.0132 0.0132
Schistosoma mansoni ap endonuclease 0.0018 0.0111 0.0111
Onchocerca volvulus 0.0016 0.0086 0.0233
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0018 0.0018
Schistosoma mansoni ran 0.0022 0.0161 0.0161
Schistosoma mansoni cpg binding protein 0.006 0.0633 0.0633
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0132 0.0359
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0284 0.3418 0.4624
Mycobacterium ulcerans hypothetical protein 0.0023 0.017 0.0196
Loa Loa (eye worm) pyruvate kinase 0.0035 0.032 0.0816
Brugia malayi hypothetical protein 0.0035 0.032 0.0868
Echinococcus multilocularis geminin 0.0336 0.4074 0.4074
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0279 0.3353 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0081 0.0144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0132 0.0359
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0086 0.0013
Onchocerca volvulus 0.0016 0.0086 0.0233
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0088
Schistosoma mansoni ap endonuclease 0.0018 0.0111 0.0111
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0036 0.0329 0.084
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0058 0.0147
Loa Loa (eye worm) hypothetical protein 0.0305 0.3682 0.9386
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0161 0.0174
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0098 0.0194
Plasmodium falciparum pyruvate kinase 0.0035 0.032 0.0865
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0102 0.0102
Brugia malayi isocitrate dehydrogenase 0.0016 0.0081 0.0219
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0132 0.0132
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0081 0.0081
Echinococcus multilocularis musashi 0.0026 0.021 0.021
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.032 0.032
Onchocerca volvulus 0.0016 0.0086 0.0233
Echinococcus multilocularis pyruvate kinase 0.0035 0.032 0.032
Onchocerca volvulus 0.0011 0.0018 0.005
Toxoplasma gondii histone lysine methyltransferase SET1 0.0108 0.1228 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0132 0.0132
Entamoeba histolytica hypothetical protein 0.0035 0.032 1
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0081 0.0219
Echinococcus multilocularis pyruvate kinase 0.0018 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.002 0.0132 0.0337
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0189 0.5657
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0089 0.0089
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0111 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0086 0.2232
Onchocerca volvulus 0.0016 0.0086 0.0233
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0014 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0817
Giardia lamblia Pyruvate kinase 0.0018 0.0107 0.2574
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0284 0.3418 0.4624
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0111 0.0301
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0047
Onchocerca volvulus 0.0023 0.017 0.0463
Echinococcus granulosus CTD small phosphatase protein like 0.0012 0.0033 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0817
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0132 0.0359
Schistosoma mansoni lamin 0.0026 0.021 0.021
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.017 0.0188
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.0059 0.0059
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.017 0.0196
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.017 0.0196
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0081 0.0081
Echinococcus multilocularis 0.0012 0.0033 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0658 0.0854
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0089 0.0227
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0658 0.0854
Plasmodium falciparum importin beta, putative 0.003 0.0261 0.0686
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0086 0.0086
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0132 0.0132
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.032 0.0869
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.032 0.0392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Brugia malayi Importin beta-1 subunit 0.003 0.0261 0.0708
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0058 0.0157
Plasmodium vivax vivapain-2 0.0016 0.0086 0.0159
Brugia malayi Cathepsin L-like precursor 0.0016 0.0086 0.0233
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0164 0.193 0.5243
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0036
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0111 0.008
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.032 0.0392
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0086 0.0086
Plasmodium vivax vivapain-2 0.0016 0.0086 0.0159
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.017 0.0196
Brugia malayi Cathepsin L-like precursor 0.0011 0.0018 0.005
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0111 0.0106
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0249
Schistosoma mansoni lamin 0.0026 0.021 0.021
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.032 0.0869
Giardia lamblia Pyruvate kinase 0.0035 0.032 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0817
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0658 0.0854
Echinococcus multilocularis lamin 0.0026 0.021 0.021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.017 0.5047
Schistosoma mansoni hypothetical protein 0.0336 0.4074 0.4074
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.021 0.0535
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0279 0.3353 0.8751
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0132 0.0132
Brugia malayi hypothetical protein 0.0011 0.0014 0.0038
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0012 0.0033 0.0033

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.