Detailed information for compound 584617

Basic information

Technical information
  • TDR Targets ID: 584617
  • Name: 2-(2-chlorophenyl)-6-hydroxy-2-(methylamino)c yclohexanone
  • MW: 253.725 | Formula: C13H16ClNO2
  • H donors: 2 H acceptors: 2 LogP: 2.01 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC1(CCCC(C1=O)O)c1ccccc1Cl
  • InChi: 1S/C13H16ClNO2/c1-15-13(8-4-7-11(16)12(13)17)9-5-2-3-6-10(9)14/h2-3,5-6,11,15-16H,4,7-8H2,1H3
  • InChiKey: WAXHSFGMMWDOAE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2-chlorophenyl)-6-hydroxy-2-(methylamino)cyclohexan-1-one
  • 6-hydroxyketamine
  • 2-(2-chlorophenyl)-6-hydroxy-2-methylaminocyclohexan-1-one
  • 2-(2-chlorophenyl)-6-hydroxy-2-methylamino-cyclohexan-1-one
  • 2-(2-chlorophenyl)-6-hydroxy-2-methylamino-1-cyclohexanone
  • 81395-75-7
  • Cyclohexanone, 2-(2-chlorophenyl)-6-hydroxy-2-(methylamino)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Onchocerca volvulus 0.0061 0.0211 0.4907
Trichomonas vaginalis glucose transporter, putative 0.0061 0.0211 0.0894
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0133 0.0606 0.0903
Schistosoma mansoni survival motor neuron protein 0.0097 0.0407 0.0544
Echinococcus multilocularis glycyl tRNA synthetase 0.0024 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0032 0.0049 0.0163
Trypanosoma cruzi hexose transporter 0.0135 0.0615 0.8651
Leishmania major myo-inositol/proton symporter (MIT) 0.0061 0.0211 0.288
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0152 0.071 1
Brugia malayi Sugar transporter family protein 0.0061 0.0211 0.0817
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0133 0.0606 0.081
Schistosoma mansoni hypothetical protein 0.0435 0.2261 0.3024
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0133 0.0606 0.0597
Echinococcus multilocularis solute carrier family 22 0.0061 0.0211 0.0282
Brugia malayi major facilitator superfamily protein 0.0061 0.0211 0.0817
Chlamydia trachomatis proline--tRNA ligase 0.0046 0.0128 0.2978
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0133 0.0606 0.081
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0153 0.0144
Loa Loa (eye worm) sugar transporter 0.0061 0.0211 0.0817
Brugia malayi hypothetical protein 0.0061 0.0211 0.0817
Echinococcus multilocularis lysyl tRNA synthetase 0.0097 0.0408 0.0545
Schistosoma mansoni hypothetical protein 0.0097 0.0407 0.0544
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trichomonas vaginalis sugar transport protein, putative 0.0061 0.0211 0.0894
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0133 0.0606 0.2415
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0133 0.0606 0.0903
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0153 0.205
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0131 0.0591 0.2355
Onchocerca volvulus 0.0097 0.0407 0.9672
Brugia malayi hypothetical protein 0.0035 0.0069 0.0243
Plasmodium falciparum lysine--tRNA ligase 0.0097 0.0408 0.0399
Brugia malayi hypothetical protein 0.0033 0.0055 0.0185
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0061 0.0211 0.506
Loa Loa (eye worm) hypothetical protein 0.0133 0.0606 0.2415
Brugia malayi hypothetical protein 0.0061 0.0211 0.0817
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0049 0.0163
Loa Loa (eye worm) hypothetical protein 0.0106 0.0457 0.1812
Entamoeba histolytica hypothetical protein 0.0097 0.0408 0.6683
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0211 0.0894
Schistosoma mansoni lysyl-tRNA synthetase 0.0097 0.0408 0.0545
Schistosoma mansoni sugar transporter 0.0061 0.0211 0.0282
Leishmania major hypothetical protein, conserved 0.0061 0.0211 0.288
Trichomonas vaginalis sugar transporter, putative 0.0135 0.0615 0.269
Echinococcus granulosus solute carrier family 22 0.0061 0.0211 0.0282
Echinococcus multilocularis synaptic vesicle 2 protein 0.0061 0.0211 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.0615 0.269
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0061 0.0211 1
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Treponema pallidum prolyl-tRNA synthetase 0.0046 0.0128 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0061 0.0211 0.2874
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0435 0.2261 0.3024
Plasmodium falciparum proline--tRNA ligase 0.0152 0.071 0.0701
Trypanosoma brucei glucose transporter, putative 0.0135 0.0615 0.8651
Loa Loa (eye worm) hypothetical protein 0.0131 0.0591 0.2355
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0069 0.0092
Trichomonas vaginalis glucose transporter, putative 0.0135 0.0615 0.269
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Onchocerca volvulus 0.0061 0.0211 0.4907
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0133 0.0606 0.2415
Echinococcus granulosus Sugar transporter ERD6 protein 0.0061 0.0211 0.0282
Echinococcus granulosus lysyl tRNA synthetase 0.0097 0.0408 0.0545
Schistosoma mansoni lysyl-tRNA synthetase 0.0097 0.0408 0.0545
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Brugia malayi glycyl-tRNA synthetase 0.0024 0.001 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0131 0.0591 0.0791
Leishmania major glucose transporter/membrane transporter D2, putative 0.0135 0.0615 0.8652
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Trypanosoma brucei glucose transporter, putative 0.0135 0.0615 0.8651
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0152 0.071 0.106
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0131 0.0591 0.2355
Brugia malayi Major Facilitator Superfamily protein 0.0061 0.0211 0.0817
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0049 0.0163
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0061 0.0211 0.6335
Echinococcus granulosus solute carrier family 22 0.0061 0.0211 0.0282
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Echinococcus multilocularis General substrate transporter 0.0374 0.1926 0.2575
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0425 0.1682
Entamoeba histolytica hypothetical protein 0.0035 0.0069 0.1006
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0425 0.1682
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0153 0.205
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0024 0.001 0.0019
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0061 0.0211 0.0201
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0435 0.2261 0.3024
Trypanosoma brucei glucose transporter, putative 0.0135 0.0615 0.8651
Entamoeba histolytica protein kinase, putative 0.0133 0.0606 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0133 0.0606 0.081
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0131 0.0591 0.0791
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0069 0.0092
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0133 0.0606 0.081
Plasmodium falciparum calcium-dependent protein kinase 2 0.0133 0.0606 0.0597
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0133 0.0606 0.081
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0435 0.2261 0.3024
Leishmania major glucose transporter, lmgt2 0.0135 0.0615 0.8652
Schistosoma mansoni hypothetical protein 0.0032 0.0049 0.0066
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0024 0.001 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0606 0.081
Leishmania major protein kinase, putative 0.0133 0.0606 0.8519
Onchocerca volvulus 0.0061 0.0211 0.4907
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0024 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0435 0.2261 1
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0211 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Brugia malayi lysyl-tRNA synthetase 0.0097 0.0408 0.1614
Echinococcus multilocularis calcium dependent protein kinase 0.0125 0.0561 0.075
Giardia lamblia Prolyl-tRNA synthetase 0.0131 0.0591 1
Schistosoma mansoni sugar transporter 0.0061 0.0211 0.0282
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0024 0.001 0.001
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Toxoplasma gondii facilitative glucose transporter GT1 0.0435 0.2261 0.3408
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0153 0.205
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Entamoeba histolytica hypothetical protein 0.0035 0.0069 0.1006
Brugia malayi Sugar transporter family protein 0.0435 0.2261 0.9111
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0049 0.0066
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0131 0.0591 0.0791
Trichomonas vaginalis sugar transporter, putative 0.0135 0.0615 0.269
Loa Loa (eye worm) hypothetical protein 0.0068 0.0251 0.0978
Echinococcus multilocularis GPCR, family 2 0.0032 0.0049 0.0066
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0133 0.0606 0.081
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0152 0.071 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0703 0.373 0.5632
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Schistosoma mansoni glucose transporter 0.0061 0.0211 0.0282
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Toxoplasma gondii lysine-tRNA ligase 0.0097 0.0408 0.0603
Onchocerca volvulus 0.0061 0.0211 0.4907
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0054 0.0169 0.0648
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0133 0.0606 0.0597
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0131 0.0591 0.0791
Trypanosoma cruzi sugar transporter, putative 0.0061 0.0211 0.2874
Brugia malayi major facilitator superfamily protein 0.0061 0.0211 0.0817
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0082 0.0328 1
Echinococcus granulosus survival motor neuron protein 1 0.0475 0.2481 0.3317
Leishmania major glucose transporter, lmgt3 0.0135 0.0615 0.8652
Trypanosoma brucei glucose transporter, putative 0.0135 0.0615 0.8651
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0049 0.0163
Plasmodium falciparum calcium-dependent protein kinase 1 0.0133 0.0606 0.0597
Trypanosoma brucei glucose transporter 2A 0.0135 0.0615 0.8651
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0082 0.0328 1
Schistosoma mansoni sugar transporter 0.0061 0.0211 0.0282
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0097 0.0408 1
Echinococcus multilocularis survival motor neuron protein 1 0.0475 0.2481 0.3317
Onchocerca volvulus 0.0061 0.0211 0.4907
Echinococcus granulosus solute carrier family 22 0.0061 0.0211 0.0282
Leishmania major glucose transporter, lmgt1 0.0135 0.0615 0.8652
Giardia lamblia Lysyl-tRNA synthetase 0.0097 0.0408 0.6849
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Schistosoma mansoni hypothetical protein 0.0032 0.0049 0.0066
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Giardia lamblia Sugar-proton symporter 0.0061 0.0211 0.346
Toxoplasma gondii sugar transporter ST1 0.0061 0.0211 0.0305
Echinococcus granulosus General substrate transporter 0.0374 0.1926 0.2575
Loa Loa (eye worm) hypothetical protein 0.0097 0.0408 0.1614
Brugia malayi Major Facilitator Superfamily protein 0.0061 0.0211 0.0817
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0131 0.0591 0.9752
Loa Loa (eye worm) hypothetical protein 0.0475 0.2481 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0135 0.0615 0.8651
Onchocerca volvulus 0.0061 0.0211 0.4907
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0024 0.001 0.0015
Onchocerca volvulus 0.0061 0.0211 0.4907
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0152 0.071 1
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0024 0.001 0.0015
Trypanosoma brucei glucose transporter, putative 0.0135 0.0615 0.8651
Trypanosoma brucei glucose transporter, putative 0.0135 0.0615 0.8651
Schistosoma mansoni microtubule-associated protein tau 0.1387 0.7478 1
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0703 0.373 0.3724
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0024 0.001 0.001
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Onchocerca volvulus 0.0061 0.0211 0.4907
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Brugia malayi MH2 domain containing protein 0.024 0.1191 0.4781
Schistosoma mansoni hypothetical protein 0.0035 0.0069 0.0092
Plasmodium vivax hexose transporter 0.0435 0.2261 0.2253
Plasmodium falciparum mitogen-activated protein kinase 2 0.0703 0.373 0.3724
Plasmodium vivax proline--tRNA ligase, putative 0.0152 0.071 0.0701
Entamoeba histolytica hypothetical protein 0.0035 0.0069 0.1006
Trypanosoma cruzi hexose transporter, putative 0.0135 0.0615 0.8651
Onchocerca volvulus 0.0061 0.0211 0.4907
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Echinococcus multilocularis solute carrier family 22 0.0061 0.0211 0.0282
Trichomonas vaginalis glucose transporter, putative 0.0135 0.0615 0.269
Plasmodium vivax lysine--tRNA ligase, putative 0.0097 0.0408 0.0399
Trypanosoma brucei glucose transporter, putative 0.0135 0.0615 0.8651
Leishmania major hypothetical protein, conserved 0.0051 0.0153 0.2057
Trypanosoma brucei sugar transporter, putative 0.0061 0.0211 0.2874
Trypanosoma brucei glucose transporter, putative 0.0135 0.0615 0.8651
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0097 0.0408 0.1769
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0024 0.001 0.0002
Echinococcus granulosus solute carrier family 22 0.0061 0.0211 0.0282
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0131 0.0591 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0131 0.0591 0.2355
Schistosoma mansoni protein kinase 0.0133 0.0606 0.081
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0153 0.0144
Mycobacterium ulcerans integral membrane transport protein 0.0061 0.0211 0.506
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Schistosoma mansoni sugar transporter 0.0061 0.0211 0.0282
Trypanosoma brucei THT1 - hexose transporter, putative 0.0135 0.0615 0.8651
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0425 0.1682
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Plasmodium falciparum calcium-dependent protein kinase 3 0.0133 0.0606 0.0597
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0153 0.0217
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Schistosoma mansoni protein kinase 0.0133 0.0606 0.081
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0133 0.0606 0.081
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0131 0.0591 0.2583
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0133 0.0606 0.2415
Onchocerca volvulus 0.0061 0.0211 0.4907
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Loa Loa (eye worm) sugar transporter 0.0435 0.2261 0.9111
Plasmodium vivax sugar transporter, putative 0.0061 0.0211 0.0201
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Loa Loa (eye worm) major facilitator superfamily transporter 0.0061 0.0211 0.0817
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0133 0.0606 0.081
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0211 0.0894
Leishmania major lysyl-tRNA synthetase, putative 0.0097 0.0408 0.5693
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0435 0.2261 0.3024
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Schistosoma mansoni hypothetical protein 0.0068 0.0251 0.0335
Trypanosoma cruzi hexose transporter, putative 0.0074 0.028 0.386
Schistosoma mansoni hypothetical protein 0.0032 0.0049 0.0066
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0024 0.001 0.0002
Onchocerca volvulus 0.0061 0.0211 0.4907
Brugia malayi Sugar transporter family protein 0.0061 0.0211 0.0817
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0407 0.1609
Brugia malayi Major Facilitator Superfamily protein 0.0061 0.0211 0.0817
Plasmodium falciparum protein kinase 7 0.123 0.6615 0.6612
Toxoplasma gondii transporter, major facilitator family protein 0.0061 0.0211 0.0305
Trypanosoma brucei glucose transporter 1E 0.0135 0.0615 0.8651
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0133 0.0606 0.0903
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0211 0.0894
Plasmodium falciparum calcium-dependent protein kinase 5 0.0133 0.0606 0.0597
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0069 0.0092
Plasmodium vivax calcium-dependent protein kinase, putative 0.0133 0.0606 0.0597
Entamoeba histolytica hypothetical protein 0.0035 0.0069 0.1006
Onchocerca volvulus 0.0061 0.0211 0.4907
Trypanosoma cruzi glucose transporter, putative 0.0061 0.0211 0.2874
Echinococcus granulosus GPCR family 2 0.0032 0.0049 0.0066
Schistosoma mansoni glucose transport protein 0.0435 0.2261 0.3024
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Schistosoma mansoni hypothetical protein 0.0032 0.0049 0.0066
Plasmodium vivax CDK-related protein kinase 6, putative 0.1847 1 1
Echinococcus multilocularis solute carrier family 22 0.0061 0.0211 0.0282
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Mycobacterium ulcerans sugar transporter 0.0061 0.0211 0.506
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0435 0.2261 0.3024
Brugia malayi hypothetical protein 0.0475 0.2481 1
Echinococcus granulosus synaptic vesicle 2 protein 0.0061 0.0211 0.0282
Brugia malayi hypothetical protein 0.0061 0.0211 0.0817
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0435 0.2261 0.3024
Trichomonas vaginalis sugar transporter, putative 0.0135 0.0615 0.269
Onchocerca volvulus 0.0061 0.0211 0.4907
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0061 0.0211 0.0282
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Echinococcus multilocularis solute carrier family 22 0.0061 0.0211 0.0282
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Toxoplasma gondii sugar transporter ST2 0.0061 0.0211 0.0305
Echinococcus granulosus tumor protein p63 0.0679 0.3598 0.4811
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0002
Onchocerca volvulus 0.0099 0.042 1
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0606 0.2648
Echinococcus granulosus calcium dependent protein kinase 0.0125 0.0561 0.075
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.042 0.0562
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0024 0.001 0.0002
Trypanosoma brucei THT1 - hexose transporter, putative 0.0135 0.0615 0.8651
Loa Loa (eye worm) MH2 domain-containing protein 0.024 0.1191 0.4781
Loa Loa (eye worm) transcription factor SMAD2 0.024 0.1191 0.4781
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0097 0.0408 0.5689
Loa Loa (eye worm) hypothetical protein 0.0051 0.0153 0.0583
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Onchocerca volvulus 0.0061 0.0211 0.4907
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0251 0.0978
Entamoeba histolytica protein kinase, putative 0.0133 0.0606 1
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0061 0.0211 0.6335
Plasmodium falciparum hexose transporter 0.0435 0.2261 0.2253
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trypanosoma cruzi hexose transporter, putative 0.0061 0.0211 0.2874
Chlamydia trachomatis lysine--tRNA ligase 0.0097 0.0408 1
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trypanosoma cruzi hexose transporter, putative 0.0135 0.0615 0.8651
Echinococcus multilocularis microtubule associated protein 2 0.1387 0.7478 1
Leishmania major threonyl-tRNA synthetase, putative 0.0024 0.001 0.0009
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0061 0.0211 0.0282
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0152 0.071 1
Schistosoma mansoni protein kinase 0.0133 0.0606 0.081
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.0615 0.269
Schistosoma mansoni glucose transport protein 0.0435 0.2261 0.3024
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0097 0.0408 0.6852
Schistosoma mansoni glycyl-tRNA synthetase 0.0024 0.001 0.0013
Giardia lamblia Hexose transporter 0.0061 0.0211 0.346
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0133 0.0606 0.8517
Onchocerca volvulus Putative transporter 0.0061 0.0211 0.4907
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0152 0.071 1
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0061 0.0211 0.506
Toxoplasma gondii sugar transporter ST3 0.0061 0.0211 0.0305
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0097 0.0408 1
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0024 0.001 0.0013
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0133 0.0606 0.0597
Echinococcus granulosus glycyl tRNA synthetase 0.0024 0.001 0.0013
Echinococcus granulosus microtubule associated protein 2 0.1387 0.7478 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0049 0.0066
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trichomonas vaginalis myo-inositol transporter, putative 0.0061 0.0211 0.0894
Echinococcus granulosus Threonyl tRNA synthetase C 0.0024 0.001 0.0013
Plasmodium falciparum calcium-dependent protein kinase 4 0.0133 0.0606 0.0597
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0082 0.0328 0.5474
Loa Loa (eye worm) hypothetical protein 0.0099 0.042 0.1664
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Loa Loa (eye worm) hypothetical protein 0.01 0.0425 0.1682
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0046 0.0128 0.2988
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0435 0.2261 0.3024
Loa Loa (eye worm) hypothetical protein 0.0061 0.0211 0.0817
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0097 0.0408 0.5689
Loa Loa (eye worm) major facilitator superfamily transporter 0.0061 0.0211 0.0817
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0153 0.0144
Brugia malayi Cam kinase protein 1 0.0133 0.0606 0.2415
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0435 0.2261 0.3024
Toxoplasma gondii protein kinase, putative 0.123 0.6615 1
Trypanosoma cruzi hexose transporter, putative 0.0135 0.0615 0.8651
Brugia malayi hypothetical protein 0.0051 0.0153 0.0583
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0211 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0211 0.0894
Schistosoma mansoni glucose transport protein 0.0435 0.2261 0.3024
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0085 0.0342 0.1477
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0049 0.0066
Onchocerca volvulus 0.0061 0.0211 0.4907
Onchocerca volvulus 0.0061 0.0211 0.4907
Echinococcus multilocularis tumor protein p63 0.0679 0.3598 0.4811

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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