Detailed information for compound 586170

Basic information

Technical information
  • TDR Targets ID: 586170
  • Name: 1-(4-iodanylphenyl)-N-isopropyl-propan-2-amin e hydrochloride
  • MW: 335.645 | Formula: C12H19ClIN
  • H donors: 1 H acceptors: 0 LogP: 4.44 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(Cc1ccc(cc1)[123I])NC(C)C.Cl
  • InChi: 1S/C12H18IN.ClH/c1-9(2)14-10(3)8-11-4-6-12(13)7-5-11;/h4-7,9-10,14H,8H2,1-3H3;1H/i13-4;
  • InChiKey: AFLDFEASYWNJGX-FOHXBPHZSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-(4-iodanylphenyl)-N-isopropyl-2-propanamine hydrochloride
  • 1-(4-iodanylphenyl)-N-propan-2-yl-propan-2-amine hydrochloride
  • [2-(4-iodanylphenyl)-1-methyl-ethyl]-isopropyl-amine hydrochloride
  • 1-(4-iodanylphenyl)-N-propan-2-ylpropan-2-amine hydrochloride
  • Iofetamine hydrochloride I 123
  • Iofetamine hydrochloride I 123 (USAN)
  • N-Isopropyl-p-iodoamphetamine (123I) hydrochloride
  • N-Isopropyl-p-iodoamphetamine (123I) hydrochloride (JAN)
  • Spectamine
  • Spectamine (TN)
  • M-123
  • Ro-23-1507/001
  • Spectamine A
  • MOLI000983
  • D01570

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis insulin receptor 0.0129 0.0686 0.0671
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0065 0.022 0.0214
Echinococcus granulosus geminin 0.0205 0.1224 0.1219
Brugia malayi Protein kinase domain containing protein 0.0129 0.0686 0.0686
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0065 0.022 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1993 0.5328
Loa Loa (eye worm) hypothetical protein 0.0146 0.0807 0.0807
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0065 0.022 0.0204
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Brugia malayi Protein-tyrosine phosphatase 0.0065 0.022 0.022
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0065 0.022 0.0214
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0065 0.022 0.0214
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0237
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0065 0.022 0.0214
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Onchocerca volvulus 4.1 G protein, putative homolog 0.0065 0.022 0.0555
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Echinococcus granulosus Endonuclease G 0.0041 0.0049 0.0043
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Schistosoma mansoni hypothetical protein 0.0205 0.1224 0.1224
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0065 0.022 0.0204
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0048 0.0105 0.0105
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Schistosoma mansoni neuropeptide receptor 0.021 0.1259 0.1259
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1993 0.5328
Onchocerca volvulus 0.0068 0.0243 0.0618
Onchocerca volvulus 0.0065 0.022 0.0555
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0068 0.0243 0.0243
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0074 0.0287 0.0287
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0549 0.3692 1
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0549 0.3692 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0068 0.0243 0.0243
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0065 0.022 0.022
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0074 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0068 0.0243 0.0243
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1993 0.5328
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0057 0.0167 0.016
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0228
Schistosoma mansoni pcd6 interacting protein-related 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0074 0.0287 0.0281
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0065 0.022 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1224 0.3214
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1429 1 1
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0065 0.022 0.1854
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0065 0.022 0.0204
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0065 0.022 0.1854
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1224 0.3214
Echinococcus multilocularis epidermal growth factor receptor 0.0059 0.018 0.0164
Schistosoma mansoni tyrosine kinase 0.0059 0.018 0.018
Schistosoma mansoni hypothetical protein 0.0205 0.1224 0.1224
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0549 0.3692 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0074 0.0287 0.0272
Brugia malayi Protein-tyrosine phosphatase 1 0.0065 0.022 0.022
Trichomonas vaginalis set domain proteins, putative 0.0286 0.1808 0.4819
Onchocerca volvulus 0.0065 0.022 0.0555
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0016 0.0016
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0065 0.022 0.1854
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0228
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0112 0.0112
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Schistosoma mansoni tyrosine kinase 0.0058 0.0172 0.0172
Brugia malayi hypothetical protein 0.0065 0.022 0.022
Trichomonas vaginalis pten, drome, putative 0.0065 0.022 0.0452
Schistosoma mansoni tyrosine kinase 0.0059 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0057 0.0167 0.0167
Echinococcus granulosus neuropeptide receptor 0.021 0.1259 0.1254
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1224 0.3214
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0016 0.0016
Echinococcus granulosus ectonucleotide 0.0057 0.0167 0.016
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1429 1 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0065 0.022 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.1303 0.3431
Schistosoma mansoni hypothetical protein 0.0146 0.0806 0.0806
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0134 0.0134
Schistosoma mansoni tyrosine kinase 0.0058 0.0172 0.0172
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0237
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Schistosoma mansoni protein tyrosine phosphatase 0.0065 0.022 0.022
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0112 0.0112
Brugia malayi Protein kinase domain containing protein 0.0072 0.0271 0.0271
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0228
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0146 0.0807 0.0807
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0065 0.022 0.0204
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0074 0.0287 0.0272
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0237
Loa Loa (eye worm) hypothetical protein 0.0071 0.0263 0.0263
Onchocerca volvulus 0.0065 0.022 0.0555
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0139 0.0753 0.0738
Leishmania major tyrosine specific protein phosphatase, putative 0.0065 0.022 0.1854
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0549 0.3692 1
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.1303 0.3431
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1224 0.3214
Onchocerca volvulus 0.0549 0.3692 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0228
Echinococcus multilocularis Endonuclease G 0.0041 0.0049 0.0033
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0065 0.022 0.0204
Brugia malayi hypothetical protein 0.0065 0.022 0.022
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0048 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Brugia malayi hypothetical protein 0.0065 0.022 0.022
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0549 0.3692 1
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0065 0.022 0.0214
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0048 0.0105 0.0098
Echinococcus multilocularis ectonucleotide 0.0057 0.0167 0.0151
Loa Loa (eye worm) TK/INSR protein kinase 0.0129 0.0686 0.0686
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0074 0.0287 0.0272
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0065 0.022 0.022
Echinococcus multilocularis geminin 0.0205 0.1224 0.121
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.1429 1 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Loa Loa (eye worm) hypothetical protein 0.0068 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0043 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0146 0.0807 0.0807
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.038 0.2479 0.5
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0228
Echinococcus granulosus epidermal growth factor receptor 0.0059 0.018 0.0173
Leishmania major hypothetical protein, conserved 0.0169 0.097 1
Onchocerca volvulus 0.0156 0.0874 0.2335
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0549 0.3692 0.3692
Onchocerca volvulus 0.0065 0.022 0.0555
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1224 0.3214
Loa Loa (eye worm) hypothetical protein 0.0068 0.0243 0.0243
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0112 0.0112
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1993 0.5328
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0134 0.0134
Echinococcus granulosus insulin receptor 0.0129 0.0686 0.068
Onchocerca volvulus 0.0286 0.1808 0.4875
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0059 0.018 0.0173
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0065 0.022 0.0214
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0139 0.0753 0.0747
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0074 0.0287 0.0281
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0549 0.3692 1
Echinococcus multilocularis hypothetical protein 0.0065 0.022 0.0204
Schistosoma mansoni protein tyrosine phosphatase 0.0065 0.022 0.022
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Brugia malayi hypothetical protein 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Echinococcus granulosus protein tyrosine phosphatase n9 0.0065 0.022 0.0214
Schistosoma mansoni tyrosine kinase 0.0129 0.0686 0.0686
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0065 0.022 0.1854
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0065 0.022 0.022
Echinococcus granulosus epidermal growth factor receptor 0.0059 0.018 0.0173
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0065 0.022 0.0204
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0065 0.022 0.0204
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0074 0.0287 0.0281
Trypanosoma cruzi hypothetical protein, conserved 0.0169 0.097 1
Echinococcus multilocularis epidermal growth factor receptor 0.0059 0.018 0.0164
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0169 0.097 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1224 0.3214
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Brugia malayi Pre-SET motif family protein 0.0251 0.1559 0.1559
Loa Loa (eye worm) hypothetical protein 0.0211 0.1269 0.1269
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0057 0.0167 0.0151
Brugia malayi Thrombospondin type 1 domain containing protein 0.0146 0.0806 0.0806
Onchocerca volvulus 0.0065 0.022 0.0555
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0549 0.3692 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1429 1 1
Brugia malayi hypothetical protein 0.0065 0.022 0.022
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0549 0.3692 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Brugia malayi Pre-SET motif family protein 0.0036 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0065 0.022 0.0204
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0065 0.022 0.0214
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1224 0.3214
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0041 0.0049 1
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1993 0.5328
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0237
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Onchocerca volvulus 0.0146 0.0806 0.2149
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.1993 0.5328
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Schistosoma mansoni tyrosine kinase 0.0129 0.0686 0.0686
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0065 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.005 0.0112 0.0112
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0068 0.0243 0.0243
Onchocerca volvulus 0.0068 0.0243 0.0618
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.1993 0.1993
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0065 0.022 0.0214
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0549 0.3692 0.3692
Trypanosoma brucei protein tyrosine phosphatase 1 0.0065 0.022 0.1854
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0065 0.022 0.0204
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0065 0.022 0.0204
Brugia malayi Protein-tyrosine phosphatase 0.022 0.1336 0.1336
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0549 0.3692 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0074 0.0287 0.0272
Echinococcus multilocularis 0.0065 0.022 0.0204
Onchocerca volvulus 0.0065 0.022 0.0555
Loa Loa (eye worm) TK/EGFR protein kinase 0.0059 0.018 0.018
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0065 0.022 0.0214
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0065 0.022 0.0204
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0068 0.0243 0.0243
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0065 0.022 0.022
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.1559 0.1559
Onchocerca volvulus 0.0065 0.022 0.0555
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0065 0.022 0.0204
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0048 0.0105 0.0089
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0228
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0146 0.0806 0.0806
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0169 0.097 0.2515
Onchocerca volvulus 0.0065 0.022 0.0555
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0074 0.0287 0.0287
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.1224 0.3287
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0074 0.0287 0.0272
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0016 0.001
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Schistosoma mansoni endonuclease related 0.0041 0.0049 0.0049
Brugia malayi endonuclease G, mitochondrial precursor 0.0041 0.0049 0.0049
Onchocerca volvulus 0.0065 0.022 0.0555
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0065 0.022 0.022
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0065 0.022 0.0214
Onchocerca volvulus 0.0065 0.022 0.0555
Trypanosoma cruzi hypothetical protein, conserved 0.0169 0.097 1
Plasmodium vivax SET domain protein, putative 0.0036 0.0016 0.5
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0074 0.0287 0.0272
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.022 0.022
Schistosoma mansoni tyrosine kinase 0.0058 0.0172 0.0172
Schistosoma mansoni tyrosine kinase 0.0059 0.018 0.018
Onchocerca volvulus 0.0065 0.022 0.0555
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0169 0.097 0.2515
Echinococcus multilocularis neuropeptide receptor 0.021 0.1259 0.1246
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0549 0.3692 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0074 0.0287 0.0287
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0074 0.0287 0.0281
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0074 0.0287 0.0287
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0068 0.0243 0.0237
Echinococcus multilocularis G protein coupled receptor 139 0.021 0.1259 0.1246
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Onchocerca volvulus 0.0065 0.022 0.0555
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0016 0.0016
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.1993 0.1993
Onchocerca volvulus 0.0065 0.022 0.0555
Schistosoma mansoni protein tyrosine phosphatase 0.0074 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Loa Loa (eye worm) protein tyrosine phosphatase 0.0065 0.022 0.022
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0074 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0065 0.022 0.0214
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0065 0.022 0.0214
Brugia malayi Furin-like cysteine rich region family protein 0.0059 0.018 0.018
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0065 0.022 0.0204
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0065 0.022 0.022
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0068 0.0243 0.0243
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.022 0.022
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0065 0.022 0.0204
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0065 0.022 0.022
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0065 0.022 0.0204
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0065 0.022 0.022
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0065 0.022 0.0214

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.