Detailed information for compound 590826

Basic information

Technical information
  • TDR Targets ID: 590826
  • Name: 4-amino-5-chloro-2-methoxy-N-quinuclidin-3-yl -benzamide hydrate hydrochloride
  • MW: 364.267 | Formula: C15H23Cl2N3O3
  • H donors: 3 H acceptors: 2 LogP: 2.07 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(N)c(cc1C(=O)NC1CN2CCC1CC2)Cl.Cl.O
  • InChi: 1S/C15H20ClN3O2.ClH.H2O/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19;;/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20);1H;1H2
  • InChiKey: NPXXKMBXEODDAF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-amino-5-chloro-2-methoxy-N-(3-quinuclidinyl)benzamide hydrate hydrochloride
  • N-(1-azabicyclo[2.2.2]octan-8-yl)-4-azanyl-5-chloro-2-methoxy-benzamide hydrate hydrochloride
  • 4-amino-N-(1-azabicyclo[2.2.2]octan-8-yl)-5-chloro-2-methoxybenzamide hydrate hydrochloride
  • zacopride

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus peptide allatostatin:somatostatin 0.006 0.0213 0.0388
Brugia malayi hypothetical protein 0.006 0.0213 0.0388
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0085 0.0375 0.0685
Brugia malayi hypothetical protein 0.006 0.0213 0.0388
Toxoplasma gondii histone deacetylase HDAC2 0.0195 0.1086 0.1894
Echinococcus multilocularis epidermal growth factor receptor 0.0128 0.0652 0.119
Loa Loa (eye worm) hypothetical protein 0.0101 0.0479 0.0874
Leishmania major hypothetical protein, conserved 0.0312 0.1838 1
Brugia malayi putative neuropeptide receptor NPR1 0.006 0.0213 0.0388
Schistosoma mansoni nuclear receptor 0.009 0.0409 0.0719
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Schistosoma mansoni biogenic amine receptor 0.006 0.0213 0.036
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0085 0.0375 0.0658
Brugia malayi Serotonin receptor 0.0331 0.1959 0.3574
Schistosoma mansoni tyrosine kinase 0.0068 0.0265 0.0456
Echinococcus granulosus histone deacetylase 6 0.0151 0.0797 0.1455
Mycobacterium tuberculosis Isocitrate lyase Icl (isocitrase) (isocitratase) 0.1577 1 1
Toxoplasma gondii histone deacetylase HDAC5 0.0078 0.0329 0.0499
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.006 0.0213 0.0388
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0877 0.5482 1
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0077 0.0134
Loa Loa (eye worm) histone deacetylase 3 0.0195 0.1086 0.198
Brugia malayi follicle stimulating hormone receptor 0.006 0.0213 0.0388
Brugia malayi gonadotropin-releasing hormone receptor 2 0.006 0.0213 0.0388
Brugia malayi hypothetical protein 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Brugia malayi hypothetical protein 0.0062 0.0229 0.0418
Loa Loa (eye worm) hypothetical protein 0.0085 0.0375 0.0685
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0108 0.0521 0.0925
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0101 0.0479 0.0847
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.006 0.0213 0.0388
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0192 0.1062 0.1937
Schistosoma mansoni hypothetical protein 0.0877 0.5482 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.006 0.0213 0.036
Echinococcus multilocularis fmrfamide receptor 0.006 0.0213 0.0388
Chlamydia trachomatis SWIB complex protein 0.0877 0.5482 1
Schistosoma mansoni histone deacetylase 0.0195 0.1086 0.1957
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0148 0.0779 0.142
Toxoplasma gondii histone deacetylase HDAC4 0.0078 0.0329 0.0499
Onchocerca volvulus 0.0312 0.1838 0.3325
Brugia malayi Histone deacetylase 1 0.0195 0.1086 0.198
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0148 0.0779 0.142
Loa Loa (eye worm) hypothetical protein 0.0101 0.0479 0.0874
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Leishmania major hypothetical protein, conserved 0.0312 0.1838 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.009 0.0409 0.0746
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0213 0.0388
Onchocerca volvulus Bile acid receptor homolog 0.0192 0.1062 0.1904
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0213 0.0388
Echinococcus multilocularis neuropeptide Y receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Schistosoma mansoni hypothetical protein 0.006 0.0213 0.036
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0148 0.0779 0.142
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0877 0.5482 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0059 0.0078
Schistosoma mansoni fusion 0.0312 0.1838 0.3333
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Echinococcus granulosus 7TM GPCR rhodopsin 0.006 0.0213 0.0388
Brugia malayi brahma associated protein 60 kDa 0.0877 0.5482 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0062 0.0229 0.0418
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni nAChR subunit 0.0062 0.0229 0.039
Schistosoma mansoni histone deacetylase 4 5 0.0151 0.0797 0.143
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Mycobacterium tuberculosis Hypothetical protein 0.0051 0.0157 0.0048
Echinococcus granulosus somatostatin receptor 0.006 0.0213 0.0388
Echinococcus multilocularis histone deacetylase 6 0.0151 0.0797 0.1455
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.009 0.0409 0.0746
Loa Loa (eye worm) hypothetical protein 0.0192 0.1062 0.1937
Brugia malayi Pre-SET motif family protein 0.0251 0.1447 0.264
Loa Loa (eye worm) hypothetical protein 0.0073 0.0294 0.0537
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Schistosoma mansoni dihydrofolate reductase 0.0044 0.011 0.0171
Echinococcus multilocularis serotonin receptor 0.006 0.0213 0.0388
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0192 0.1062 0.1914
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Echinococcus multilocularis histone deacetylase 6 0.0151 0.0797 0.1455
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0059 0.0107
Loa Loa (eye worm) hypothetical protein 0.0192 0.1062 0.1937
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0062 0.0229 0.0418
Brugia malayi Furin-like cysteine rich region family protein 0.0128 0.0652 0.119
Onchocerca volvulus 0.006 0.0213 0.0348
Loa Loa (eye worm) hypothetical protein 0.0085 0.0375 0.0685
Echinococcus granulosus neuropeptides capa receptor 0.006 0.0213 0.0388
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0069 0.027 0.0493
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0213 0.036
Brugia malayi GnHR receptor homolog 0.006 0.0213 0.0388
Brugia malayi nuclear hormone receptor 0.009 0.0409 0.0746
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Brugia malayi YY1-associated factor 2 0.0312 0.1838 0.3353
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Loa Loa (eye worm) brahma associated protein 0.0877 0.5482 1
Echinococcus multilocularis G protein coupled receptor 139 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Loa Loa (eye worm) LGC-31 protein 0.0148 0.0779 0.142
Leishmania major histone deacetylase, putative 0.0195 0.1086 0.5596
Onchocerca volvulus 0.0148 0.0779 0.1385
Schistosoma mansoni neuropeptide F-like receptor 0.006 0.0213 0.036
Loa Loa (eye worm) hypothetical protein 0.0192 0.1062 0.1937
Schistosoma mansoni neurotransmitter gated ion channel 0.0085 0.0375 0.0658
Schistosoma mansoni hypothetical protein 0.006 0.0213 0.036
Trypanosoma cruzi WLM domain containing protein, putative 0.0312 0.1838 1
Brugia malayi Steroid receptor seven-up type 2 0.0192 0.1062 0.1937
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Loa Loa (eye worm) neuropeptide F receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0312 0.1838 0.3353
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0312 0.1838 0.3192
Loa Loa (eye worm) hypothetical protein 0.0101 0.0479 0.0874
Loa Loa (eye worm) hypothetical protein 0.0192 0.1062 0.1937
Schistosoma mansoni nAChR subunit 0.0148 0.0779 0.1395
Loa Loa (eye worm) hypothetical protein 0.0195 0.1086 0.198
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0148 0.0779 0.142
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0312 0.1838 1
Trypanosoma cruzi WLM domain containing protein, putative 0.0312 0.1838 1
Chlamydia trachomatis DNA topoisomerase I 0.0877 0.5482 1
Brugia malayi Pre-SET motif family protein 0.0036 0.0059 0.0107
Echinococcus granulosus thymidylate synthase 0.0108 0.0521 0.0951
Echinococcus multilocularis SWI:SNF matrix associated 0.0877 0.5482 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0779 0.142
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0312 0.1838 0.3281
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0518 0.0413
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0312 0.1838 0.3353
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0192 0.1062 0.1937
Brugia malayi hypothetical protein 0.006 0.0213 0.0388
Toxoplasma gondii histone deacetylase HDAC3 0.0195 0.1086 0.1894
Loa Loa (eye worm) neuropeptide F receptor 0.006 0.0213 0.0388
Brugia malayi Tachykinin-like peptides receptor 99D 0.006 0.0213 0.0388
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0148 0.0779 0.142
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.013 0.0237
Echinococcus granulosus histone deacetylase 1 0.0195 0.1086 0.198
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.006 0.0213 0.0388
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0148 0.0779 0.142
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0213 0.036
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0195 0.1086 0.1975
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.006 0.0213 0.0388
Trypanosoma cruzi histone deacetylase, putative 0.0151 0.0797 0.3909
Plasmodium vivax histone deacetylase, putative 0.0151 0.0797 0.1362
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.006 0.0213 0.036
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Brugia malayi nuclear receptor NHR-88 0.0192 0.1062 0.1937
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0192 0.1062 0.1937
Onchocerca volvulus Neuropeptide F receptor homolog 0.006 0.0213 0.0348
Brugia malayi hypothetical protein 0.006 0.0213 0.0388
Onchocerca volvulus 0.0192 0.1062 0.1904
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.013 0.002
Schistosoma mansoni acetylcholine receptor-related 0.0062 0.0229 0.039
Echinococcus granulosus SWI:SNF matrix associated 0.0877 0.5482 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0192 0.1062 0.1937
Schistosoma mansoni amine GPCR 0.006 0.0213 0.036
Echinococcus multilocularis dihydrofolate reductase 0.0044 0.011 0.02
Brugia malayi hypothetical protein 0.0062 0.0229 0.0418
Brugia malayi G protein-coupled receptor 0.006 0.0213 0.0388
Schistosoma mansoni amine GPCR 0.006 0.0213 0.036
Echinococcus multilocularis g protein coupled receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0148 0.0779 0.1395
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0312 0.1838 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0375 0.0685
Mycobacterium tuberculosis Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) 0.1577 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.006 0.0213 0.036
Schistosoma mansoni tyrosine kinase 0.0069 0.027 0.0465
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0062 0.0229 0.0418
Schistosoma mansoni neuropeptide receptor 0.006 0.0213 0.036
Brugia malayi nuclear receptor NHR-88 0.009 0.0409 0.0746
Leishmania major histone deacetylase, putative 0.0151 0.0797 0.3909
Echinococcus granulosus biogenic amine 5HT receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) GABA receptor subunit 0.0085 0.0375 0.0685
Echinococcus granulosus thyroid hormone receptor alpha 0.009 0.0409 0.0746
Brugia malayi hypothetical protein 0.006 0.0213 0.0388
Brugia malayi hypothetical protein 0.009 0.0409 0.0746
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0213 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0077 0.0134
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0101 0.0479 0.0874
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Brugia malayi steroid hormone receptor 0.0192 0.1062 0.1937
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0192 0.1062 0.1904
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0062 0.0229 0.0418
Onchocerca volvulus 0.0148 0.0779 0.1385
Leishmania major hypothetical protein, conserved 0.0312 0.1838 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0192 0.1062 0.1937
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0312 0.1838 1
Onchocerca volvulus 0.006 0.0213 0.0348
Echinococcus multilocularis histone deacetylase 8 0.0078 0.0329 0.0601
Schistosoma mansoni nuclear hormone receptor 0.0192 0.1062 0.1914
Loa Loa (eye worm) follicle stimulating hormone receptor 0.006 0.0213 0.0388
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0148 0.0779 0.1395
Brugia malayi Thioredoxin reductase 0.0047 0.013 0.0237
Loa Loa (eye worm) nuclear receptor NHR-67 0.009 0.0409 0.0746
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0213 0.036
Trypanosoma cruzi histone deacetylase, putative 0.0151 0.0797 0.3909
Brugia malayi Nuclear hormone receptor E75 0.009 0.0409 0.0746
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0192 0.1062 0.1937
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0877 0.5482 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0213 0.0388
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0047 0.0132 0.0212
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0148 0.0779 0.142
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0195 0.1086 0.1975
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0312 0.1838 0.3353
Brugia malayi nuclear receptor RXR 0.0101 0.0479 0.0874
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0192 0.1062 0.1937
Loa Loa (eye worm) nuclear receptor nhr-7B 0.009 0.0409 0.0746
Schistosoma mansoni neuropeptide receptor 0.006 0.0213 0.036
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.006 0.0213 0.036
Trypanosoma cruzi hypothetical protein, conserved 0.0312 0.1838 1
Schistosoma mansoni tyrosine kinase 0.0068 0.0265 0.0456
Brugia malayi ORL1-like opioid receptor 0.006 0.0213 0.0388
Mycobacterium tuberculosis Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) 0.1577 1 1
Brugia malayi hypothetical protein 0.006 0.0213 0.0388
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.009 0.0409 0.0746
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0062 0.0229 0.0418
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0148 0.0779 0.142
Loa Loa (eye worm) glutathione reductase 0.0047 0.013 0.0237
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.006 0.0213 0.0388
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0877 0.5482 1
Schistosoma mansoni neuropeptide receptor 0.006 0.0213 0.036
Brugia malayi neuropeptide F receptor 0.006 0.0213 0.0388
Schistosoma mansoni growth hormone secretagogue receptor 0.006 0.0213 0.036
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0148 0.0779 0.142
Brugia malayi dihydrofolate reductase family protein 0.0044 0.011 0.02
Loa Loa (eye worm) histone deacetylase 0.0151 0.0797 0.1455
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Echinococcus multilocularis SWI:SNF matrix associated 0.0877 0.5482 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0192 0.1062 0.1937
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0779 0.142
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Brugia malayi putative neuropeptide receptor 0.006 0.0213 0.0388
Schistosoma mansoni histone deacetylase hda2 0.0151 0.0797 0.143
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0192 0.1062 0.1937
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0213 0.036
Onchocerca volvulus Histone deacetylase 10 homolog 0.0078 0.0329 0.0562
Brugia malayi chromobox protein homolog 3 0.0039 0.0077 0.014
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Echinococcus granulosus glycine receptor subunit alpha 1 0.0148 0.0779 0.142
Echinococcus granulosus histone deacetylase 6 0.0151 0.0797 0.1455
Brugia malayi Dopamine receptor protein 1 0.006 0.0213 0.0388
Leishmania major hypothetical protein, conserved 0.0312 0.1838 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0192 0.1062 0.1914
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0312 0.1838 1
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.013 0.0237
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0312 0.1838 0.3353
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0062 0.0229 0.0418
Brugia malayi nuclear hormone receptor 0.0192 0.1062 0.1937
Trichomonas vaginalis histone deacetylase, putative 0.0195 0.1086 0.1975
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0273 0.0499
Loa Loa (eye worm) hypothetical protein 0.0101 0.0479 0.0874
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0148 0.0779 0.142
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0192 0.1062 0.1914
Brugia malayi hypothetical protein 0.0121 0.0607 0.1108
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0192 0.1062 0.1914
Brugia malayi nuclear hormone receptor family member nhr-6 0.009 0.0409 0.0746
Echinococcus granulosus histone deacetylase 3 0.0195 0.1086 0.198
Schistosoma mansoni zinc finger protein 0.0312 0.1838 0.3333
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0192 0.1062 0.1937
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0062 0.0229 0.0418
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0148 0.0779 0.142
Brugia malayi hypothetical protein 0.0051 0.0157 0.0286
Echinococcus granulosus ring and YY1 binding protein 0.0312 0.1838 0.3353
Toxoplasma gondii histone deacetylase HDAC1 0.0151 0.0797 0.1362
Echinococcus multilocularis histone deacetylase 7 0.0151 0.0797 0.1455
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0148 0.0779 0.142
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.006 0.0213 0.0388
Echinococcus granulosus 7tm_1 domain containing protein 0.006 0.0213 0.0388
Echinococcus multilocularis histone deacetylase 3 0.0195 0.1086 0.198
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0192 0.1062 0.1937
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0213 0.0388
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0312 0.1838 1
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0877 0.5482 1
Schistosoma mansoni hypothetical protein 0.0877 0.5482 1
Onchocerca volvulus 0.0286 0.1671 0.302
Onchocerca volvulus 0.0233 0.133 0.2395
Echinococcus granulosus neuropeptide receptor A26 0.006 0.0213 0.0388
Trypanosoma cruzi histone deacetylase, putative 0.0078 0.0329 0.1168
Onchocerca volvulus 0.006 0.0213 0.0348
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0148 0.0779 0.142
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0213 0.036
Loa Loa (eye worm) DR-78 0.009 0.0409 0.0746
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0877 0.5482 1
Leishmania major histone deacetylase, putative 0.0151 0.0797 0.3909
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0518 0.0413
Loa Loa (eye worm) hypothetical protein 0.0192 0.1062 0.1937
Echinococcus multilocularis histone deacetylase 0.0151 0.0797 0.1455
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.006 0.0213 0.036
Loa Loa (eye worm) TK/INSR protein kinase 0.0041 0.009 0.0165
Echinococcus granulosus neuropeptide receptor 0.006 0.0213 0.0388
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.006 0.0213 0.036
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.0255 0.0465
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.009 0.0409 0.0708
Echinococcus granulosus serotonin receptor 0.006 0.0213 0.0388
Schistosoma mansoni TRABID protein (C64 family) 0.0312 0.1838 0.3333
Mycobacterium ulcerans isocitrate lyase AceAb 0.1577 1 1
Loa Loa (eye worm) hypothetical protein 0.0312 0.1838 0.3353
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0101 0.0479 0.0847
Echinococcus granulosus thyrotropin releasing hormone receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0148 0.0779 0.142
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Echinococcus multilocularis orexin receptor type 2 0.006 0.0213 0.0388
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0148 0.0779 0.142
Brugia malayi hypothetical protein 0.0101 0.0479 0.0874
Echinococcus multilocularis thymidylate synthase 0.0108 0.0521 0.0951
Trypanosoma cruzi histone deacetylase 1, putative 0.0195 0.1086 0.5596
Trichomonas vaginalis histone deacetylase, putative 0.0195 0.1086 0.1975
Onchocerca volvulus 0.006 0.0213 0.0348
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni histone deacetylase hda2 0.0078 0.0329 0.0573
Brugia malayi SWIB/MDM2 domain containing protein 0.0877 0.5482 1
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0062 0.0229 0.0418
Schistosoma mansoni alpha-1 adrenergic receptor 0.006 0.0213 0.036
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0148 0.0779 0.142
Echinococcus granulosus Zinc finger RanBP2 type 0.0312 0.1838 0.3353
Plasmodium vivax histone deacetylase 1, putative 0.0195 0.1086 0.1894
Schistosoma mansoni hypothetical protein 0.0877 0.5482 1
Echinococcus granulosus dihydrofolate reductase 0.0044 0.011 0.02
Brugia malayi Cytochrome P450 family protein 0.0066 0.0255 0.0465
Echinococcus multilocularis glycine receptor subunit beta 0.0148 0.0779 0.142
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0108 0.0521 0.0416
Schistosoma mansoni biogenic amine receptor 0.006 0.0213 0.036
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0101 0.0479 0.0874
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0213 0.036
Onchocerca volvulus 0.009 0.0409 0.0708
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0148 0.0779 0.142
Echinococcus granulosus glycine receptor subunit beta 0.0148 0.0779 0.142
Schistosoma mansoni nuclear hormone receptor 0.009 0.0409 0.0719
Schistosoma mansoni nuclear receptor nhr-48 0.009 0.0409 0.0719
Echinococcus multilocularis insulin receptor 0.0041 0.009 0.0165
Echinococcus multilocularis sex peptide receptor 0.006 0.0213 0.0388
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0152 0.0805 0.3953
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0213 0.0388
Echinococcus granulosus insulin receptor 0.0041 0.009 0.0165
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.006 0.0213 0.0348
Echinococcus granulosus histone deacetylase 7 0.0151 0.0797 0.1455
Brugia malayi hypothetical protein 0.0062 0.0229 0.0418
Loa Loa (eye worm) G-protein coupled receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) TYRA-2 protein 0.006 0.0213 0.0388
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0062 0.0229 0.0418
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Onchocerca volvulus 0.006 0.0213 0.0348
Onchocerca volvulus 0.006 0.0213 0.0348
Onchocerca volvulus 0.006 0.0213 0.0348
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0213 0.036
Onchocerca volvulus 0.006 0.0213 0.0348
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0096 0.0168
Brugia malayi hypothetical protein 0.0062 0.0229 0.0418
Toxoplasma gondii thioredoxin reductase 0.0047 0.013 0.0131
Echinococcus multilocularis neuropeptide receptor A26 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Leishmania major hypothetical protein, conserved 0.0312 0.1838 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.006 0.0213 0.0388
Brugia malayi orphan nuclear receptor NR2E1 0.009 0.0409 0.0746
Schistosoma mansoni hypothetical protein 0.006 0.0213 0.036
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Echinococcus granulosus histone deacetylase 0.0151 0.0797 0.1455
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.006 0.0213 0.036
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0148 0.0779 0.1395
Onchocerca volvulus 0.006 0.0213 0.0348
Echinococcus multilocularis zinc finger protein Ran binding 0.0312 0.1838 0.3353
Echinococcus granulosus hypothetical protein 0.0466 0.2833 0.5168
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.009 0.0409 0.0719
Giardia lamblia Histone deacetylase 0.0195 0.1086 0.5
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0233 0.133 0.2404
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.1447 0.264
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Brugia malayi histone deacetylase 3 (HD3) 0.0195 0.1086 0.198
Brugia malayi Dopamine receptor protein 2 0.006 0.0213 0.0388
Echinococcus granulosus orexin receptor type 2 0.006 0.0213 0.0388
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0148 0.0779 0.142
Schistosoma mansoni RAR-like nuclear receptor 0.0192 0.1062 0.1914
Brugia malayi glutathione reductase 0.0047 0.013 0.0237
Echinococcus granulosus histone deacetylase 8 0.0078 0.0329 0.0601
Echinococcus multilocularis neuropeptides capa receptor 0.006 0.0213 0.0388
Onchocerca volvulus 0.0085 0.0375 0.0646
Schistosoma mansoni nAChR subunit 0.0062 0.0229 0.039
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0148 0.0779 0.142
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0518 0.0413
Loa Loa (eye worm) histone deacetylase 7A 0.0151 0.0797 0.1455
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0213 0.036
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0213 0.0388
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.006 0.0213 0.0388
Plasmodium vivax hypothetical protein, conserved 0.0877 0.5482 1
Brugia malayi Nuclear hormone receptor-like 1 0.0192 0.1062 0.1937
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0596 0.0491
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0518 0.0413
Loa Loa (eye worm) hypothetical protein 0.0085 0.0375 0.0685
Brugia malayi Protein kinase domain containing protein 0.0041 0.009 0.0165
Echinococcus multilocularis neuropeptide receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) nuclear hormone receptor 0.009 0.0409 0.0746
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Echinococcus multilocularis g protein coupled receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Onchocerca volvulus 0.0148 0.0779 0.1385
Plasmodium vivax glutathione reductase, putative 0.0047 0.013 0.0131
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0312 0.1838 0.3353
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.013 0.0131
Brugia malayi thymidylate synthase 0.0108 0.0521 0.0951
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0779 0.142
Echinococcus granulosus nuclear receptor 2DBD gamma 0.009 0.0409 0.0746
Schistosoma mansoni neuropeptide F-like receptor 0.006 0.0213 0.036
Loa Loa (eye worm) ACC-1 protein 0.0148 0.0779 0.142
Onchocerca volvulus 0.0108 0.0521 0.0914
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni thyroid hormone receptor 0.0192 0.1062 0.1914
Loa Loa (eye worm) hypothetical protein 0.0192 0.1062 0.1937
Echinococcus granulosus FTZ F1 alpha 0.0192 0.1062 0.1937
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0213 0.0388
Trypanosoma brucei histone deacetylase 2 0.0078 0.0329 0.1168
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0152 0.0805 0.1262
Brugia malayi histone deacetylase 1 (HD1) 0.0195 0.1086 0.198
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.006 0.0213 0.0388
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0152 0.0805 0.3953
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0213 0.0388
Echinococcus multilocularis neuropeptide s receptor 0.006 0.0213 0.0388
Brugia malayi brahma associated protein 60 kDa 0.0877 0.5482 1
Schistosoma mansoni amine GPCR 0.006 0.0213 0.036
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0148 0.0779 0.142
Onchocerca volvulus 0.0085 0.0375 0.0646
Brugia malayi G-protein coupled receptor 0.006 0.0213 0.0388
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0192 0.1062 0.1937
Brugia malayi histone deacetylase 11 0.0078 0.0329 0.0601
Onchocerca volvulus 0.0312 0.1838 0.3325
Schistosoma mansoni myosin xvIII 0.006 0.0213 0.036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0213 0.036
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0877 0.5482 1
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0148 0.0779 0.142
Echinococcus granulosus glycine receptor subunit beta 0.0148 0.0779 0.142
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.005 0.0091
Brugia malayi G protein-coupled receptor F59B2.13 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Loa Loa (eye worm) melatonin receptor type 1A 0.006 0.0213 0.0388
Onchocerca volvulus Protein ultraspiracle homolog 0.0192 0.1062 0.1904
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0779 0.142
Trypanosoma cruzi hypothetical protein, conserved 0.0312 0.1838 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.006 0.0213 0.036
Echinococcus granulosus biogenic amine 5HT receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0085 0.0375 0.0685
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0077 0.0099
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0041 0.009 0.0165
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni retinoic acid receptor RXR 0.0192 0.1062 0.1914
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0148 0.0779 0.142
Echinococcus granulosus g protein coupled receptor 0.006 0.0213 0.0388
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0779 0.142
Schistosoma mansoni histone deacetylase 4 5 0.0151 0.0797 0.143
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0101 0.0479 0.0874
Echinococcus granulosus neuropeptide Y receptor 0.006 0.0213 0.0388
Trypanosoma brucei hypothetical protein, conserved 0.0312 0.1838 1
Schistosoma mansoni nuclear hormone receptor 0.009 0.0409 0.0719
Plasmodium vivax histone deacetylase, putative 0.0078 0.0329 0.0499
Echinococcus granulosus neuropeptide FF receptor 2 0.006 0.0213 0.0388
Schistosoma mansoni RNA binding protein 0.0312 0.1838 0.3333
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0192 0.1062 0.1914
Brugia malayi Cation transporter family protein 0.0148 0.0779 0.142
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.006 0.0213 0.0388
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0192 0.1062 0.1937
Onchocerca volvulus 0.006 0.0213 0.0348
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0312 0.1838 0.3353
Loa Loa (eye worm) hypothetical protein 0.0078 0.0329 0.0601
Echinococcus granulosus zinc finger protein Ran binding 0.0312 0.1838 0.3353
Loa Loa (eye worm) hypothetical protein 0.0073 0.0294 0.0537
Schistosoma mansoni nAChR subunit 0.0148 0.0779 0.1395
Echinococcus multilocularis tachykinin peptides receptor 99D 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0148 0.0779 0.142
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0059 0.0078
Plasmodium vivax histone deacetylase 2, putative 0.0151 0.0797 0.1362
Echinococcus granulosus nAChR subunit 0.0148 0.0779 0.142
Schistosoma mansoni tyrosine kinase 0.0068 0.0265 0.0456
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0312 0.1838 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0148 0.0779 0.142
Brugia malayi conserved hypotetical protein 0.009 0.0409 0.0746
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Loa Loa (eye worm) G-protein coupled receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) histone deacetylase 1 0.0195 0.1086 0.198
Echinococcus multilocularis histone deacetylase 6 0.0151 0.0797 0.1455
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.006 0.0213 0.0388
Schistosoma mansoni hypothetical protein 0.0312 0.1838 0.3333
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0195 0.1086 0.1975
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0157 0.028
Plasmodium falciparum histone deacetylase 1 0.0195 0.1086 0.1786
Loa Loa (eye worm) hypothetical protein 0.0316 0.1863 0.3398
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0312 0.1838 0.3353
Echinococcus multilocularis histone deacetylase 1 0.0195 0.1086 0.198
Brugia malayi Nuclear hormone receptor E75 0.009 0.0409 0.0746
Echinococcus granulosus g protein coupled receptor 0.006 0.0213 0.0388
Brugia malayi neuropeptide F receptor 0.006 0.0213 0.0388
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0148 0.0779 0.142
Brugia malayi Heterochromatin protein 1 0.0069 0.0273 0.0499
Schistosoma mansoni biogenic amine receptor 0.006 0.0213 0.036
Toxoplasma gondii ran binding protein 0.0312 0.1838 0.3281
Brugia malayi Serotonin receptor 0.006 0.0213 0.0388
Schistosoma mansoni chromobox protein 0.0069 0.0273 0.0471
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Loa Loa (eye worm) thymidylate synthase 0.0108 0.0521 0.0951
Echinococcus granulosus glycine receptor subunit alpha 1 0.0148 0.0779 0.142
Loa Loa (eye worm) hypothetical protein 0.0085 0.0375 0.0685
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0085 0.0375 0.0658
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.006 0.0213 0.0388
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0192 0.1062 0.1937
Loa Loa (eye worm) histone deacetylase 11 0.0078 0.0329 0.0601
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0192 0.1062 0.1937
Echinococcus multilocularis FTZ F1 alpha 0.0192 0.1062 0.1937
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0148 0.0779 0.142
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0148 0.0779 0.142
Loa Loa (eye worm) hypothetical protein 0.0085 0.0375 0.0685
Echinococcus granulosus G protein coupled receptor 139 0.006 0.0213 0.0388
Brugia malayi nuclear receptor NHR-67 0.009 0.0409 0.0746
Schistosoma mansoni nAChR subunit 0.0148 0.0779 0.1395
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0148 0.0779 0.142
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0213 0.0388
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.006 0.0213 0.036
Brugia malayi Nuclear hormone receptor-like 1 0.0101 0.0479 0.0874
Loa Loa (eye worm) hypothetical protein 0.0036 0.0059 0.0107
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Schistosoma mansoni hypothetical protein 0.006 0.0213 0.036
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0213 0.0388
Echinococcus multilocularis serotonin receptor 0.006 0.0213 0.0388
Schistosoma mansoni nAChR subunit 0.0148 0.0779 0.1395
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0148 0.0779 0.142
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0152 0.0805 0.1376
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Loa Loa (eye worm) TK/EGFR protein kinase 0.0128 0.0652 0.119
Leishmania major histone deacetylase, putative 0.0195 0.1086 0.5596
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Echinococcus multilocularis Nuclear hormone receptor HR96 0.009 0.0409 0.0746
Mycobacterium ulcerans thymidylate synthase 0.0108 0.0521 0.0416
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0192 0.1062 0.1937
Echinococcus multilocularis fmrfamide receptor 0.006 0.0213 0.0388
Echinococcus multilocularis g-protein coupled receptor 0.006 0.0213 0.0388
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0596 0.0491
Echinococcus multilocularis g protein coupled receptor 0.006 0.0213 0.0388
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0192 0.1062 0.1937
Echinococcus multilocularis thyroid hormone receptor alpha 0.0192 0.1062 0.1937
Brugia malayi Serotonin/octopamine receptor family protein 7 0.006 0.0213 0.0388
Brugia malayi larval opioid receptor 0.006 0.0213 0.0388
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0192 0.1062 0.1937
Echinococcus multilocularis chromobox protein 1 0.0069 0.0273 0.0499
Echinococcus granulosus g-protein coupled receptor 0.006 0.0213 0.0388
Mycobacterium leprae Isocitrate lyase 0.0739 0.4595 0.4535
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Echinococcus granulosus sex peptide receptor 0.006 0.0213 0.0388
Schistosoma mansoni brg-1 associated factor 0.0877 0.5482 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.013 0.0237
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0041 0.009 0.0165
Loa Loa (eye worm) ACC-1 protein 0.0148 0.0779 0.142
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0085 0.0375 0.0685
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0192 0.1062 0.1914
Echinococcus granulosus ecdysone induced protein 78C 0.0192 0.1062 0.1937
Brugia malayi G-protein coupled receptor 0.006 0.0213 0.0388
Echinococcus multilocularis neuropeptide FF receptor 2 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0596 0.0491
Brugia malayi tailless protein 0.009 0.0409 0.0746
Echinococcus granulosus neuropeptide s receptor 0.006 0.0213 0.0388
Echinococcus granulosus neuropeptide Y receptor 0.006 0.0213 0.0388
Trypanosoma brucei histone deacetylase 1 0.0195 0.1086 0.5596
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0096 0.0134
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.009 0.0409 0.0719
Onchocerca volvulus 0.0233 0.133 0.2395
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0192 0.1062 0.1937
Entamoeba histolytica histone deacetylase, putative 0.0195 0.1086 1
Brugia malayi hypothetical protein 0.009 0.0409 0.0746
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.006 0.0213 0.0388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0213 0.036
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0213 0.0388
Schistosoma mansoni adenoreceptor 0.006 0.0213 0.036
Brugia malayi hypothetical protein 0.0101 0.0479 0.0874
Brugia malayi RE15519p 0.006 0.0213 0.0388
Onchocerca volvulus Putative nachr subunit 0.0148 0.0779 0.1385
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.009 0.0409 0.0746
Echinococcus multilocularis Nuclear hormone receptor HR96 0.009 0.0409 0.0746
Schistosoma mansoni neuropeptide receptor 0.006 0.0213 0.036
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Onchocerca volvulus 0.009 0.0409 0.0708
Schistosoma mansoni tyrosine kinase 0.0041 0.009 0.0136
Loa Loa (eye worm) hypothetical protein 0.0171 0.0927 0.1691
Echinococcus multilocularis neuropeptide receptor 0.006 0.0213 0.0388
Echinococcus granulosus neuropeptides capa receptor 0.006 0.0213 0.0388
Brugia malayi sulfakinin receptor protein 0.006 0.0213 0.0388
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0192 0.1062 0.1937
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0148 0.0779 0.1395
Trypanosoma brucei histone deacetylase 3 0.0151 0.0797 0.3909
Schistosoma mansoni acetylcholine receptor subunit beta 0.0062 0.0229 0.039
Schistosoma mansoni nAChR subunit 0.0148 0.0779 0.1395
Schistosoma mansoni coup transcription factor 0.0192 0.1062 0.1914
Trichomonas vaginalis histone deacetylase, putative 0.0195 0.1086 0.1975
Echinococcus granulosus alpha 1A adrenergic receptor 0.006 0.0213 0.0388
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.006 0.0213 0.0388
Onchocerca volvulus 0.006 0.0213 0.0348
Echinococcus granulosus histone deacetylase 6 0.0151 0.0797 0.1455
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.006 0.0213 0.036
Echinococcus granulosus nuclear receptor nhr 48 0.009 0.0409 0.0746
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0192 0.1062 0.1937
Trypanosoma cruzi histone deacetylase 1, putative 0.0195 0.1086 0.5596
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0192 0.1062 0.1937
Echinococcus multilocularis dro:myosuppressin receptor 0.006 0.0213 0.0388
Plasmodium falciparum histone deacetylase, putative 0.0151 0.0797 0.1248
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0192 0.1062 0.1937
Echinococcus multilocularis G-protein coupled receptor, putative 0.006 0.0213 0.0388
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0312 0.1838 0.3353
Onchocerca volvulus 0.0062 0.0229 0.0379
Echinococcus granulosus glycine receptor subunit alpha 1 0.0148 0.0779 0.142
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0192 0.1062 0.1937
Schistosoma mansoni amine GPCR 0.006 0.0213 0.036
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0148 0.0779 0.142
Loa Loa (eye worm) hypothetical protein 0.003 0.0023 0.0041
Echinococcus granulosus nAChR subunit 0.0085 0.0375 0.0685
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0108 0.0521 0.0416
Onchocerca volvulus 0.006 0.0213 0.0348
Trichomonas vaginalis set domain proteins, putative 0.0286 0.1671 0.3044
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0213 0.0388
Echinococcus multilocularis 0.004 0.0082 0.0149
Loa Loa (eye worm) hypothetical protein 0.0312 0.1838 0.3353
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni histone deacetylase 0.0195 0.1086 0.1957
Brugia malayi excitatory GABA receptor EXP-1A 0.0148 0.0779 0.142
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0051 0.0157 0.016
Loa Loa (eye worm) hypothetical protein 0.0192 0.1062 0.1937
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Echinococcus granulosus fmrfamide receptor 0.006 0.0213 0.0388
Brugia malayi Dopamine receptor 0.006 0.0213 0.0388
Schistosoma mansoni neurotransmitter gated ion channel 0.0062 0.0229 0.039
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0518 0.0413
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Onchocerca volvulus 0.006 0.0213 0.0348
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0085 0.0375 0.0685
Echinococcus multilocularis ecdysone induced protein 78C 0.0192 0.1062 0.1937
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0192 0.1062 0.1937
Loa Loa (eye worm) hypothetical protein 0.0101 0.0479 0.0874
Loa Loa (eye worm) hypothetical protein 0.0039 0.0077 0.014
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0273 0.0492
Trichomonas vaginalis conserved hypothetical protein 0.0877 0.5482 1
Brugia malayi Cation transporter family protein 0.0233 0.133 0.2426
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni amine GPCR 0.006 0.0213 0.036
Plasmodium falciparum histone deacetylase 2 0.0151 0.0797 0.1248
Echinococcus multilocularis glycine receptor subunit beta 0.0148 0.0779 0.142
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0596 0.0491
Brugia malayi hypothetical protein 0.006 0.0213 0.0388
Trypanosoma brucei histone deacetylase 4 0.0151 0.0797 0.3909
Echinococcus multilocularis nAChR subunit 0.0148 0.0779 0.142
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0192 0.1062 0.1937
Schistosoma mansoni tyrosine kinase 0.0069 0.027 0.0465
Trypanosoma brucei hypothetical protein, conserved 0.0312 0.1838 1
Brugia malayi Histone deacetylase family protein 0.0151 0.0797 0.1455
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0273 0.0492
Loa Loa (eye worm) acetylcholine receptor protein 0.0062 0.0229 0.0418
Echinococcus granulosus chromobox protein 1 0.0069 0.0273 0.0499
Schistosoma mansoni opsin-like receptor 0.006 0.0213 0.036
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0213 0.0388
Schistosoma mansoni zinc finger protein 0.009 0.0409 0.0719
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Brugia malayi photoreceptor-specific nuclear receptor 0.0192 0.1062 0.1937
Onchocerca volvulus 0.006 0.0213 0.0348
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0096 0.0168
Brugia malayi hypothetical protein 0.0062 0.0229 0.0418
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.009 0.0409 0.0708
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.009 0.0409 0.0746
Echinococcus multilocularis nuclear receptor nhr 48 0.009 0.0409 0.0746
Onchocerca volvulus 0.0062 0.0229 0.0379
Echinococcus multilocularis SWI:SNF matrix associated 0.0877 0.5482 1
Schistosoma mansoni histone deacetylase 1 2 3 0.0078 0.0329 0.0573
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0059 0.0078
Schistosoma mansoni opsin-like receptor 0.006 0.0213 0.036
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.006 0.0213 0.0388
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0192 0.1062 0.1937
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0192 0.1062 0.1937
Echinococcus granulosus dro:myosuppressin receptor 0.006 0.0213 0.0388
Brugia malayi nuclear receptor RXR 0.009 0.0409 0.0746
Brugia malayi nuclear hormone receptor family member odr-7 0.009 0.0409 0.0746
Echinococcus granulosus g protein coupled receptor 0.006 0.0213 0.0388
Schistosoma mansoni hypothetical protein 0.0051 0.0158 0.026
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Echinococcus granulosus allatostatin A receptor 0.006 0.0213 0.0388
Onchocerca volvulus 0.006 0.0213 0.0348
Loa Loa (eye worm) hypothetical protein 0.0192 0.1062 0.1937
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Loa Loa (eye worm) hypothetical protein 0.0085 0.0375 0.0685
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0192 0.1062 0.1937
Trichomonas vaginalis histone deacetylase, putative 0.0195 0.1086 0.1975
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni peptide (allatostatin)-like receptor 0.006 0.0213 0.036
Echinococcus multilocularis neuropeptide Y receptor 0.006 0.0213 0.0388
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0213 0.0388
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0192 0.1062 0.1937
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0148 0.0779 0.142
Echinococcus multilocularis somatostatin receptor 0.006 0.0213 0.0388
Brugia malayi Cation transporter family protein 0.0148 0.0779 0.142
Schistosoma mansoni opsin-like receptor 0.006 0.0213 0.036
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0877 0.5482 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0518 0.0413
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Brugia malayi ecdysone receptor 0.009 0.0409 0.0746
Echinococcus multilocularis neuropeptides capa receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0233 0.133 0.2426
Onchocerca volvulus 0.006 0.0213 0.0348
Brugia malayi Histone deacetylase family protein 0.0151 0.0797 0.1455
Loa Loa (eye worm) steroid hormone receptor 0.0192 0.1062 0.1937
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0192 0.1062 0.1937
Brugia malayi hypothetical protein 0.006 0.0213 0.0388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0213 0.036
Echinococcus multilocularis allatostatin A receptor 0.006 0.0213 0.0388
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0148 0.0779 0.142
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0062 0.0229 0.0418
Schistosoma mansoni tyrosine kinase 0.0041 0.009 0.0136
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0312 0.1838 0.3325
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0059 0.0107
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0312 0.1838 1
Brugia malayi ecdysteroid receptor 0.0192 0.1062 0.1937
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.006 0.0213 0.0388
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0062 0.0229 0.0418
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0213 0.0388
Schistosoma mansoni biogenic amine (5HT) receptor 0.006 0.0213 0.036
Schistosoma mansoni histamine h1 receptor 0.006 0.0213 0.036
Brugia malayi Melatonin receptor type 1A 0.006 0.0213 0.0388
Schistosoma mansoni thyroid hormone receptor 0.0192 0.1062 0.1914
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0062 0.0229 0.0418
Echinococcus multilocularis nAChR subunit 0.0085 0.0375 0.0685
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0192 0.1062 0.1937
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0062 0.0229 0.0418
Loa Loa (eye worm) dihydrofolate reductase 0.0044 0.011 0.02
Schistosoma mansoni nAChR subunit 0.0148 0.0779 0.1395
Trichomonas vaginalis histone deacetylase, putative 0.0195 0.1086 0.1975
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0213 0.0388
Echinococcus granulosus neuropeptide receptor 0.006 0.0213 0.0388
Trichomonas vaginalis histone deacetylase, putative 0.0195 0.1086 0.1975
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0192 0.1062 0.1937
Trypanosoma cruzi hypothetical protein, conserved 0.0312 0.1838 1
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0312 0.1838 0.3353
Brugia malayi hypothetical protein 0.006 0.0213 0.0388
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.006 0.0213 0.0388
Brugia malayi Nuclear hormone receptor-like 1 0.0101 0.0479 0.0874
Echinococcus multilocularis conserved hypothetical protein 0.0406 0.2446 0.4462
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0152 0.0805 0.1376
Mycobacterium ulcerans isocitrate lyase Icl 0.1577 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0213 0.0388
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0148 0.0779 0.142
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0213 0.0388
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0059 0.0107
Onchocerca volvulus 0.0312 0.1838 0.3325
Echinococcus multilocularis ring and YY1 binding protein 0.0312 0.1838 0.3353
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0779 0.142
Loa Loa (eye worm) hypothetical protein 0.0312 0.1838 0.3353
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0148 0.0779 0.142
Schistosoma mansoni nAChR subunit 0.0148 0.0779 0.1395
Trypanosoma cruzi histone deacetylase, putative 0.0151 0.0797 0.3909
Loa Loa (eye worm) hypothetical protein 0.0148 0.0779 0.142
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Mycobacterium tuberculosis Probable reductase 0.0107 0.0518 0.0413
Trypanosoma brucei histone deacetylase, putative 0.0151 0.0797 0.3909
Onchocerca volvulus 0.0233 0.133 0.2395
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.009 0.0409 0.0746
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Loa Loa (eye worm) hypothetical protein 0.0233 0.133 0.2426
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0085 0.0375 0.0685
Echinococcus multilocularis alpha 1A adrenergic receptor 0.006 0.0213 0.0388
Onchocerca volvulus 0.0062 0.0229 0.0379
Onchocerca volvulus 0.006 0.0213 0.0348
Echinococcus granulosus epidermal growth factor receptor 0.0069 0.027 0.0493
Brugia malayi Dihydrofolate reductase 0.0044 0.011 0.02
Echinococcus granulosus chromobox protein 1 0.0069 0.0273 0.0499
Schistosoma mansoni tyrosine kinase 0.0128 0.0652 0.1165
Schistosoma mansoni nuclear receptor 0.009 0.0409 0.0719
Schistosoma mansoni chromobox protein 0.0069 0.0273 0.0471
Trypanosoma cruzi histone deacetylase, putative 0.0078 0.0329 0.1168
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Echinococcus multilocularis chromobox protein 1 0.0069 0.0273 0.0499
Loa Loa (eye worm) hypothetical protein 0.009 0.0409 0.0746
Echinococcus multilocularis epidermal growth factor receptor 0.0069 0.027 0.0493
Brugia malayi AKH receptor 0.006 0.0213 0.0388
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0152 0.0805 0.3953
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0233 0.133 0.2404
Onchocerca volvulus 0.0312 0.1838 0.3325
Echinococcus granulosus Nuclear hormone receptor HR96 0.009 0.0409 0.0746
Echinococcus granulosus epidermal growth factor receptor 0.0128 0.0652 0.119
Onchocerca volvulus 0.0047 0.0132 0.02
Onchocerca volvulus 0.0877 0.5482 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0213 0.0388
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0062 0.0229 0.0418
Schistosoma mansoni steroid hormone receptor ad4bp 0.0192 0.1062 0.1914
Schistosoma mansoni neuropeptide f receptor 76f 0.006 0.0213 0.036
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.006 0.0213 0.0388
Schistosoma mansoni neurotransmitter gated ion channel 0.0062 0.0229 0.039

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF. (Class of assay: confirmatory) [Related pubchem assays: 995 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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