Detailed information for compound 663992

Basic information

Technical information
  • TDR Targets ID: 663992
  • Name: ethyl 1-[3-(2-fluorophenoxy)-2-hydroxypropyl] piperidine-4-carboxylate
  • MW: 325.375 | Formula: C17H24FNO4
  • H donors: 1 H acceptors: 2 LogP: 2.13 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C1CCN(CC1)CC(COc1ccccc1F)O
  • InChi: 1S/C17H24FNO4/c1-2-22-17(21)13-7-9-19(10-8-13)11-14(20)12-23-16-6-4-3-5-15(16)18/h3-6,13-14,20H,2,7-12H2,1H3
  • InChiKey: RWRZJJBYRKFBNJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ethyl 1-[3-(2-fluorophenoxy)-2-hydroxy-propyl]piperidine-4-carboxylate
  • 1-[3-(2-fluorophenoxy)-2-hydroxypropyl]-4-piperidinecarboxylic acid ethyl ester
  • 1-[3-(2-fluorophenoxy)-2-hydroxy-propyl]isonipecotic acid ethyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus voltage dependent calcium channel 0.0108 0.3154 0.3968
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0108 0.3154 0.4485
Brugia malayi hypothetical protein 0.0015 0.0138 0.0184
Echinococcus multilocularis chromobox protein 2 0.0036 0.081 0.1019
Echinococcus multilocularis transient receptor potential gamma protein 0.0108 0.3154 0.3968
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0085 0.2396 0.3323
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0426 0.1221
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0426 0.1221
Trichomonas vaginalis chromobox protein, putative 0.0218 0.6721 0.6706
Loa Loa (eye worm) hypothetical protein 0.017 0.5148 0.7137
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0108 0.3154 0.3968
Schistosoma mansoni lamin 0.002 0.0316 0.0438
Loa Loa (eye worm) RecQ helicase 0.0023 0.0389 0.0529
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Schistosoma mansoni hypothetical protein 0.0108 0.3154 0.4374
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0686 0.0951
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0686 0.1989
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0108 0.3154 0.4374
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0073 0.0092
Leishmania major hypothetical protein, conserved 0.0108 0.3154 1
Schistosoma mansoni hypothetical protein 0.0116 0.341 0.4729
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0052 0.1326 0.1878
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0108 0.3154 0.4485
Schistosoma mansoni calcium-activated potassium channel 0.0108 0.3154 0.4374
Echinococcus granulosus GPCR family 2 0.0054 0.1392 0.1751
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Brugia malayi cation channel family protein 0.0108 0.3154 0.4485
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.081 0.2394
Loa Loa (eye worm) hypothetical protein 0.0055 0.1423 0.1964
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0108 0.3154 0.3968
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0108 0.3154 0.4374
Echinococcus multilocularis chromobox protein 1 0.0218 0.6721 0.8455
Entamoeba histolytica hypothetical protein 0.0036 0.081 0.0767
Brugia malayi chromobox protein homolog 3 0.0122 0.3615 0.5143
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.081 0.0767
Plasmodium vivax heterochromatin protein 1, putative 0.0036 0.081 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0108 0.3154 0.3968
Toxoplasma gondii transporter, cation channel family protein 0.0108 0.3154 1
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0108 0.3154 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0042 0.1009 0.1269
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.081 0.0767
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0178 0.5424 0.7519
Echinococcus multilocularis short transient receptor potential channel 6 0.0108 0.3154 0.3968
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0108 0.3154 0.3968
Echinococcus granulosus Chromo domain 0.0036 0.081 0.1019
Brugia malayi hypothetical protein 0.0024 0.0426 0.0595
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Schistosoma mansoni transient receptor potential channel 0.0108 0.3154 0.4374
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0108 0.3154 0.3968
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Brugia malayi Importin beta-1 subunit 0.0022 0.0362 0.0504
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0671 0.0845
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0108 0.3154 0.4485
Loa Loa (eye worm) hypothetical protein 0.0036 0.081 0.1114
Brugia malayi follicle stimulating hormone receptor 0.0178 0.5424 0.7722
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0108 0.3154 0.4485
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0085 0.2396 0.3014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 1 1
Schistosoma mansoni polycystin 1-related 0.0015 0.0138 0.0191
Echinococcus granulosus snurportin 1 0.0233 0.721 0.9071
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0389 0.0344
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Loa Loa (eye worm) hypothetical protein 0.0033 0.071 0.0975
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0233 0.721 1
Echinococcus multilocularis short transient receptor potential channel 6 0.0108 0.3154 0.3968
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.3154 0.4374
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.071 0.2069
Plasmodium vivax hypothetical protein, conserved 0.0036 0.081 1
Plasmodium falciparum importin beta, putative 0.0022 0.0362 0.3915
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0903 0.1252
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0108 0.3154 0.4374
Loa Loa (eye worm) helicase 0.0036 0.081 0.1114
Loa Loa (eye worm) hypothetical protein 0.0032 0.0686 0.0941
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.3154 0.3968
Schistosoma mansoni two-pore calcium channel 0.0108 0.3154 0.4374
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Loa Loa (eye worm) hypothetical protein 0.002 0.0304 0.041
Schistosoma mansoni chromobox protein 0.0036 0.081 0.1124
Schistosoma mansoni voltage-gated ion channel 0.0108 0.3154 0.4374
Trichomonas vaginalis chromobox protein, putative 0.0036 0.081 0.0767
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0151 0.1059
Echinococcus granulosus sodium and chloride dependent glycine 0.0052 0.1326 0.1668
Trichomonas vaginalis chromobox protein, putative 0.0036 0.081 0.0767
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0108 0.3154 1
Schistosoma mansoni vesicular amine transporter 0.0108 0.3154 0.4374
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Loa Loa (eye worm) voltage-gated calcium channel 0.0108 0.3154 0.4367
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Loa Loa (eye worm) heterochromatin protein 1 0.0218 0.6721 0.932
Echinococcus granulosus two pore calcium channel protein 2 0.0108 0.3154 0.3968
Toxoplasma gondii transporter, cation channel family protein 0.0108 0.3154 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.081 0.0767
Onchocerca volvulus 0.0036 0.081 0.0851
Echinococcus granulosus TRP transient receptor potential channel 0.0108 0.3154 0.3968
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0108 0.3154 0.4374
Brugia malayi jmjC domain containing protein 0.0104 0.3034 0.4314
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0122 0.3615 0.4401
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0108 0.3154 0.3968
Echinococcus multilocularis voltage dependent calcium channel 0.0108 0.3154 0.3968
Loa Loa (eye worm) hypothetical protein 0.0037 0.0868 0.1193
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.3154 0.4374
Echinococcus granulosus geminin 0.0128 0.3814 0.4798
Echinococcus multilocularis tumor protein p63 0.0256 0.7949 1
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0108 0.3154 0.3968
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0085 0.2396 0.3323
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0426 0.4787
Schistosoma mansoni lipoxygenase 0.0042 0.1009 0.1399
Loa Loa (eye worm) hypothetical protein 0.0096 0.2759 0.382
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0054 0.1392 0.1973
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0108 0.3154 0.3968
Loa Loa (eye worm) hypothetical protein 0.0052 0.1326 0.1829
Schistosoma mansoni chromobox protein 0.0218 0.6721 0.9321
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0108 0.3154 0.4367
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.081 0.1124
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0234 0.0325
Schistosoma mansoni lipoxygenase 0.0015 0.0138 0.0191
Trichomonas vaginalis hypothetical protein 0.0036 0.081 0.0767
Schistosoma mansoni hypothetical protein 0.0233 0.721 1
Brugia malayi Associated with TFs and helicases family protein 0.0036 0.081 0.1144
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0108 0.3154 0.4374
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0046 0.1144 0.2312
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0108 0.3154 0.4374
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.081 0.0767
Echinococcus granulosus importin subunit beta 1 0.0022 0.0362 0.0455
Loa Loa (eye worm) hypothetical protein 0.0054 0.1392 0.1921
Echinococcus granulosus hypothetical protein 0.0108 0.3154 0.3968
Schistosoma mansoni hypothetical protein 0.0054 0.1392 0.1931
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0686 0.0863
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0052 0.1326 0.1829
Loa Loa (eye worm) hypothetical protein 0.0114 0.3356 0.4648
Echinococcus granulosus sodium channel protein 0.0108 0.3154 0.3968
Brugia malayi Cyclic-nucleotide gated cation channel 0.0108 0.3154 0.4485
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0108 0.3154 0.3968
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0108 0.3154 1
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0108 0.3154 0.3968
Loa Loa (eye worm) hypothetical protein 0.0036 0.081 0.1114
Echinococcus granulosus RUN 0.0015 0.0138 0.0173
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.3154 0.3968
Loa Loa (eye worm) hypothetical protein 0.0015 0.0138 0.018
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0108 0.3154 1
Echinococcus granulosus calcium activated potassium channel 0.0108 0.3154 0.3968
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.3154 0.3968
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 1 1
Schistosoma mansoni aldehyde dehydrogenase 0.0046 0.1144 0.1587
Plasmodium vivax SET domain protein, putative 0.0033 0.071 0.8645
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0104 0.3034 0.3817
Echinococcus granulosus hyperpolarization activated cyclic 0.0108 0.3154 0.3968
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0319 1 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0156 0.4708 1
Echinococcus granulosus peregrin 0.0032 0.0686 0.0863
Schistosoma mansoni voltage-dependent calcium channel 0.0108 0.3154 0.4374
Schistosoma mansoni hypothetical protein 0.0032 0.0686 0.0951
Echinococcus multilocularis transfer RNA-Gly 0.0108 0.3154 0.3968
Brugia malayi cation channel family protein 0.0108 0.3154 0.4485
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0018 0.0228 0.0182
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Echinococcus multilocularis calcium activated potassium channel 0.0108 0.3154 0.3968
Loa Loa (eye worm) hypothetical protein 0.0022 0.0362 0.049
Echinococcus multilocularis hyperpolarization activated cyclic 0.0108 0.3154 0.3968
Brugia malayi hypothetical protein 0.0015 0.0152 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.081 0.0767
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0389 0.049
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0085 0.2396 0.3315
Loa Loa (eye worm) hypothetical protein 0.0122 0.3615 0.5008
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0108 0.3154 0.4485
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Loa Loa (eye worm) hypothetical protein 0.0036 0.081 0.1114
Toxoplasma gondii hypothetical protein 0.0108 0.3154 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0052 0.1326 0.1838
Echinococcus granulosus sodium leak channel non selective protein 0.0108 0.3154 0.3968
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0108 0.3154 0.3968
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0108 0.3154 0.3968
Loa Loa (eye worm) latrophilin receptor protein 2 0.0054 0.1392 0.1921
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0156 0.4708 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.081 0.0767
Echinococcus granulosus lipoxygenase domain containing protein 0.0015 0.0138 0.0173
Brugia malayi Heterochromatin protein 1 0.0218 0.6721 0.9572
Schistosoma mansoni cellular tumor antigen P53 0.0037 0.0868 0.1203
Toxoplasma gondii aldehyde dehydrogenase 0.0046 0.1144 0.3478
Brugia malayi hypothetical protein 0.0036 0.081 0.1144
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.081 0.1124
Loa Loa (eye worm) hypothetical protein 0.0036 0.081 0.1114
Echinococcus multilocularis RUN 0.0015 0.0138 0.0173
Loa Loa (eye worm) doublecortin family protein 0.0015 0.0138 0.018
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0036 0.081 0.1019
Echinococcus multilocularis importin subunit beta 1 0.0022 0.0362 0.0455
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0036 0.081 1
Echinococcus granulosus chromobox protein 1 0.0218 0.6721 0.8455
Echinococcus multilocularis potassium voltage gated channel protein 0.0108 0.3154 0.3968
Trichomonas vaginalis Heterochromatin protein, putative 0.0036 0.081 0.0767
Echinococcus granulosus tumor protein p63 0.0256 0.7949 1
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0389 0.0543
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0903 0.1252
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0108 0.3154 0.3817
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.081 0.0767
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0389 0.0344
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.03 0.3078
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0108 0.3154 0.3968
Schistosoma mansoni intermediate filament proteins 0.002 0.0316 0.0438
Echinococcus granulosus Chromobox protein 3 0.0036 0.081 0.1019
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.2458 0.2423
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0085 0.2396 0.3014
Echinococcus granulosus intermediate filament protein 0.002 0.0316 0.0397
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0054 0.1392 0.1751
Echinococcus multilocularis peregrin 0.0032 0.0686 0.0863
Loa Loa (eye worm) pigment dispersing factor receptor c 0.017 0.5148 0.7137
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0108 0.3154 0.4485
Echinococcus multilocularis lamin dm0 0.002 0.0316 0.0397
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Leishmania major hypothetical protein, conserved 0.0024 0.0426 0.1221
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0108 0.3154 0.4374
Brugia malayi CHD4 protein 0.0036 0.081 0.1144
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0018 0.0228 0.0182
Plasmodium falciparum heterochromatin protein 1 0.0036 0.081 1
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.081 0.0767
Leishmania major importin beta-1 subunit, putative 0.0018 0.0228 0.0583
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0073 0.0084
Onchocerca volvulus 0.002 0.0316 0.0225
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.071 0.0985
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0108 0.3154 0.3968
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.081 0.0767
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.2458 0.2423
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 1 1
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0686 0.0941
Brugia malayi ion channel NompC 0.0108 0.3154 0.4485
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Trichomonas vaginalis chromobox protein, putative 0.0132 0.3916 0.3888
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0108 0.3154 0.4485
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0013 0.0073 0.0092
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.081 0.0767
Schistosoma mansoni hypothetical protein 0.0054 0.1392 0.1931
Brugia malayi isocitrate dehydrogenase 0.0013 0.0073 0.0092
Brugia malayi hypothetical protein 0.0108 0.3154 0.4485
Schistosoma mansoni chromobox protein 0.0036 0.081 0.1124
Echinococcus multilocularis two pore calcium channel protein 2 0.0108 0.3154 0.3968
Plasmodium vivax multidomain scavenger receptor, putative 0.0015 0.0138 0.088
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0108 0.3154 0.4374
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0085 0.2396 0.3014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.081 0.0767
Echinococcus granulosus bloom syndrome protein 0.0023 0.0389 0.049
Trichomonas vaginalis importin beta-1, putative 0.0018 0.0228 0.0182
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0108 0.3154 0.3968
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.3154 0.3968
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.071 0.0894
Echinococcus multilocularis snurportin 1 0.0233 0.721 0.9071
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0108 0.3154 0.3968
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0132 0.3916 0.4782
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.081 0.1114
Plasmodium vivax importin-beta 2, putative 0.0022 0.0362 0.3915
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.081 0.2394
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0108 0.3154 0.3968
Giardia lamblia Fructose-bisphosphate aldolase 0.0319 1 1
Brugia malayi latrophilin 2 splice variant baaae 0.0116 0.341 0.485
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Loa Loa (eye worm) hypothetical protein 0.0015 0.0138 0.018
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.081 0.1019
Schistosoma mansoni loxhd1 0.0015 0.0138 0.0191
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Loa Loa (eye worm) voltage-gated potassium channel 0.0108 0.3154 0.4367
Loa Loa (eye worm) voltage-gated potassium channel 0.0108 0.3154 0.4367
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0108 0.3154 0.3968
Echinococcus granulosus lamin 0.002 0.0316 0.0397
Loa Loa (eye worm) isocitrate dehydrogenase 0.0013 0.0073 0.009
Echinococcus multilocularis sodium and chloride dependent glycine 0.0052 0.1326 0.1668
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.071 0.0985
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0042 0.1009 0.1269
Schistosoma mansoni ryanodine receptor related 0.0108 0.3154 0.4374
Onchocerca volvulus 0.0036 0.081 0.0851
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0054 0.1392 0.1751
Brugia malayi olfactory channel protein osm-9 0.0108 0.3154 0.4485
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Loa Loa (eye worm) ion channel NompC 0.0108 0.3154 0.4367
Onchocerca volvulus 0.0259 0.8039 1
Echinococcus granulosus two pore calcium channel protein 1 0.0108 0.3154 0.3968
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0013 0.0073 0.0084
Echinococcus multilocularis potassium voltage gated channel protein 0.0108 0.3154 0.3968
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0108 0.3154 0.3968
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.3154 0.3968
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.081 0.0767
Brugia malayi Bromodomain containing protein 0.0032 0.0686 0.0966
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0108 0.3154 0.3968
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Echinococcus multilocularis hyperpolarization activated cyclic 0.0108 0.3154 0.3968
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0426 0.4787
Brugia malayi Calcitonin receptor-like protein seb-1 0.017 0.5148 0.7329
Onchocerca volvulus Alhambra homolog 0.0032 0.0686 0.0694
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0108 0.3154 0.3968
Toxoplasma gondii HEAT repeat-containing protein 0.0022 0.0362 0.0937
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0104 0.3034 0.3817
Loa Loa (eye worm) hypothetical protein 0.002 0.0316 0.0427
Onchocerca volvulus 0.0108 0.3154 0.3817
Toxoplasma gondii hypothetical protein 0.0108 0.3154 1
Echinococcus multilocularis ryanodine receptor 44f 0.0108 0.3154 0.3968
Loa Loa (eye worm) hypothetical protein 0.0052 0.1326 0.1829
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.3154 0.3968
Echinococcus multilocularis GPCR, family 2 0.0054 0.1392 0.1751
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0686 0.831
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.3154 0.3968
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0013 0.0073 0.0084
Brugia malayi hypothetical protein 0.0015 0.0138 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.3615 0.3585
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.081 0.0767
Onchocerca volvulus 0.0096 0.2759 0.3318
Onchocerca volvulus 0.002 0.0316 0.0225
Echinococcus granulosus lipoxygenase domain containing protein 0.0015 0.0138 0.0173
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.081 0.0767
Brugia malayi Transient-receptor-potential like protein 0.0108 0.3154 0.4485
Schistosoma mansoni hypothetical protein 0.0036 0.081 0.1124
Brugia malayi intermediate filament protein 0.002 0.0316 0.0438
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.081 0.1124
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0046 0.1144 0.144
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0108 0.3154 0.4485
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0108 0.3154 0.4485
Schistosoma mansoni jumonji domain containing protein 0.0083 0.2339 0.3244
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.3154 0.4374
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0108 0.3154 0.4374
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0108 0.3154 1
Echinococcus multilocularis lamin 0.002 0.0316 0.0397
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0903 0.1242
Schistosoma mansoni hypothetical protein 0.0128 0.3814 0.5289
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.081 0.0767
Trypanosoma cruzi importin beta-1 subunit, putative 0.0018 0.0228 0.0583
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.081 0.0767
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.071 0.0985
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Brugia malayi Isocitrate dehydrogenase 0.0013 0.0073 0.0092
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0426 0.1146
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Loa Loa (eye worm) hypothetical protein 0.0036 0.081 0.1114
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 1 1
Echinococcus multilocularis sodium channel protein 0.0108 0.3154 0.3968
Echinococcus multilocularis Chromo domain 0.0036 0.081 0.1019
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0108 0.3154 0.3968
Schistosoma mansoni hypothetical protein 0.0128 0.3814 0.5289
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.3154 0.3968
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0156 0.4708 0.5
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0108 0.3154 0.3968
Schistosoma mansoni aldehyde dehydrogenase 0.0046 0.1144 0.1587
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0036 0.081 0.2394
Brugia malayi jmjC domain containing protein 0.0039 0.0903 0.1276
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.3154 0.3968
Brugia malayi Latrophilin receptor protein 2 0.0054 0.1392 0.1973
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.081 0.1019
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0085 0.2396 0.3405
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0073 0.0084
Brugia malayi voltage-dependent calcium channel 0.0108 0.3154 0.4485
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0145 0.0234
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0013 0.0073 0.0101
Echinococcus granulosus voltage gated potassium channel 0.0108 0.3154 0.3968
Brugia malayi Pre-SET motif family protein 0.0227 0.7021 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Treponema pallidum fructose-bisphosphate aldolase 0.0319 1 0.5
Entamoeba histolytica hypothetical protein 0.0036 0.081 0.0767
Plasmodium vivax hypothetical protein, conserved 0.0036 0.081 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0073 0.0092
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0108 0.3154 0.3968
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.3154 0.4374
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0108 0.3154 0.4485
Brugia malayi Doublecortin family protein 0.0015 0.0138 0.0184
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0108 0.3154 0.3968
Echinococcus multilocularis sodium and chloride dependent glycine 0.0052 0.1326 0.1668
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0108 0.3154 0.3968
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0686 0.0863
Echinococcus multilocularis shaker cognate 0.0108 0.3154 0.3968
Echinococcus multilocularis Chromobox protein 3 0.0036 0.081 0.1019
Entamoeba histolytica hypothetical protein 0.0036 0.081 0.0767
Echinococcus granulosus jumonji domain containing protein 0.0044 0.109 0.1371
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.081 0.0767
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0108 0.3154 0.4374
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0108 0.3154 0.4485
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.081 0.0767
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.109 0.1371
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0426 0.1221
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.081 0.0767
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.3154 0.4374
Brugia malayi Pre-SET motif family protein 0.0033 0.071 0.1001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0054 0.1392 0.1751
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0108 0.3154 0.3968
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0108 0.3154 0.3968
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0085 0.2396 0.3323
Echinococcus granulosus transient receptor potential gamma protein 0.0108 0.3154 0.3968
Echinococcus granulosus shaker cognate 0.0108 0.3154 0.3968
Echinococcus granulosus voltage dependent calcium channel 0.0108 0.3154 0.3968
Echinococcus granulosus sodium and chloride dependent glycine 0.0052 0.1326 0.1668
Schistosoma mansoni 60S ribosomal protein L21 0.0108 0.3154 0.4374
Schistosoma mansoni lamin 0.002 0.0316 0.0438
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 1 1
Echinococcus granulosus voltage gated hydrogen channel 1 0.0108 0.3154 0.3968
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0108 0.3154 0.3968
Echinococcus multilocularis isocitrate dehydrogenase 0.0013 0.0073 0.0092
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.3154 0.3968
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0013 0.0073 0.0092
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0046 0.1144 0.3533
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Loa Loa (eye worm) hypothetical protein 0.0036 0.081 0.1114
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.3154 0.3968
Echinococcus granulosus short transient receptor potential channel 6 0.0108 0.3154 0.3968
Leishmania major hypothetical protein, unknown function 0.0108 0.3154 1
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.3615 0.3585
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.081 0.0767
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0108 0.3154 0.4485
Echinococcus multilocularis sodium leak channel non selective protein 0.0108 0.3154 0.3968
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.3154 0.3968
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.003 0.0041
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0903 0.1136
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.071 0.0894
Echinococcus multilocularis potassium voltage gated channel protein 0.0108 0.3154 0.3968
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.017 0.5148 0.7329
Echinococcus granulosus voltage gated potassium channel 0.0108 0.3154 0.3968
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0108 0.3154 0.3968
Brugia malayi Intermediate filament tail domain containing protein 0.002 0.0316 0.0438
Schistosoma mansoni hypothetical protein 0.0015 0.0138 0.0191
Schistosoma mansoni rab6-interacting 0.0015 0.0138 0.0191
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0036 0.081 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0108 0.3154 0.3968
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.071 0.0894
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0046 0.1144 0.144
Echinococcus multilocularis two pore calcium channel protein 1 0.0108 0.3154 0.3968
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0108 0.3154 0.3968
Loa Loa (eye worm) hypothetical protein 0.0036 0.081 0.1114
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0108 0.3154 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.081 0.0767
Echinococcus multilocularis geminin 0.0128 0.3814 0.4798
Entamoeba histolytica hypothetical protein 0.0018 0.0228 0.0182
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0108 0.3154 0.3817
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0108 0.3154 0.4374
Schistosoma mansoni hypothetical protein 0.0054 0.1392 0.1931
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0227 0.7021 0.9737
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0426 0.4787
Echinococcus granulosus potassium large conductance calcium activated 0.0108 0.3154 0.3968
Schistosoma mansoni transient receptor potential channel 0.0108 0.3154 0.4374
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0903 0.1136
Trichomonas vaginalis set domain proteins, putative 0.0259 0.8039 0.803
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.3154 0.3968
Loa Loa (eye worm) ryanodine receptor 0.0108 0.3154 0.4367
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.3154 0.3968
Trichomonas vaginalis chromobox protein, putative 0.0218 0.6721 0.6706
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0108 0.3154 0.3122
Echinococcus granulosus chromobox protein 2 0.0036 0.081 0.1019
Echinococcus multilocularis chromobox protein 1 0.0218 0.6721 0.8455
Brugia malayi M-phase phosphoprotein, mpp8 0.0036 0.081 0.1144
Echinococcus granulosus lamin dm0 0.002 0.0316 0.0397
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.003 0.0031
Schistosoma mansoni transient receptor potential channel 0.0108 0.3154 0.4374
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0036 0.081 0.1019
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.3154 0.3968
Brugia malayi Valyl-tRNA synthetase 0.0036 0.081 0.1144
Schistosoma mansoni hypothetical protein 0.0054 0.1392 0.1931
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0108 0.3154 0.4374
Plasmodium falciparum LCCL domain-containing protein 0.0015 0.0138 0.088
Echinococcus granulosus ryanodine receptor 44f 0.0108 0.3154 0.3968
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.3154 0.4374
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0085 0.2396 0.3014
Schistosoma mansoni voltage-gated cation channel 0.0108 0.3154 0.4374
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.081 0.0767
Echinococcus multilocularis voltage dependent calcium channel 0.0108 0.3154 0.3968
Echinococcus granulosus short transient receptor potential channel 6 0.0108 0.3154 0.3968
Onchocerca volvulus 0.0037 0.0868 0.0924
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.3154 0.3968
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0108 0.3154 0.4485
Echinococcus multilocularis conserved hypothetical protein 0.0108 0.3154 0.3968
Schistosoma mansoni transient receptor potential channel 4 0.0108 0.3154 0.4374
Trypanosoma brucei importin beta-1 subunit, putative 0.0022 0.0362 0.1014
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.002 0.0316 0.0427
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0108 0.3154 0.4485
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0108 0.3154 0.3968
Brugia malayi PHD-finger family protein 0.0032 0.0686 0.0966
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Loa Loa (eye worm) intermediate filament protein 0.002 0.0316 0.0427
Brugia malayi Protein cec-1. 0.0036 0.081 0.1144
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0073 0.0084
Echinococcus granulosus Polycystic kidney disease protein 0.0015 0.0138 0.0173
Trichomonas vaginalis chromobox protein, putative 0.0036 0.081 0.0767
Trypanosoma brucei importin beta-1 subunit, putative 0.0022 0.0362 0.1014
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.1785 0.2466
Echinococcus granulosus chromobox protein 1 0.0218 0.6721 0.8455
Schistosoma mansoni sodium/chloride dependent transporter 0.0052 0.1326 0.1838
Echinococcus multilocularis lipoxygenase domain containing protein 0.0015 0.0138 0.0173
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.081 0.1124
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0108 0.3154 0.3968
Toxoplasma gondii transporter, cation channel family protein 0.0108 0.3154 1
Brugia malayi SET domain containing protein 0.0037 0.0849 0.1199
Loa Loa (eye worm) calcium channel 0.0108 0.3154 0.4367
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0108 0.3154 0.4485
Brugia malayi RNA, U transporter 1 0.0062 0.1667 0.2365
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0686 0.1989
Onchocerca volvulus 0.0068 0.1867 0.2189
Echinococcus multilocularis lipoxygenase domain containing protein 0.0015 0.0138 0.0173
Echinococcus multilocularis musashi 0.002 0.0316 0.0397
Schistosoma mansoni importin beta-1 0.0022 0.0362 0.0501
Echinococcus multilocularis voltage gated potassium channel 0.0108 0.3154 0.3968
Echinococcus multilocularis potassium large conductance calcium activated 0.0108 0.3154 0.3968
Echinococcus multilocularis voltage gated potassium channel 0.0108 0.3154 0.3968
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0073 0.0092
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0108 0.3154 0.4367
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0108 0.3154 0.3122
Schistosoma mansoni chromobox protein 0.0218 0.6721 0.9321
Loa Loa (eye worm) voltage-dependent calcium channel 0.0108 0.3154 0.4367
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 1 1
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0108 0.3154 0.4367
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0108 0.3154 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0054 0.1392 0.1751
Trichomonas vaginalis chromobox protein, putative 0.0132 0.3916 0.3888
Schistosoma mansoni rab6-interacting 0.0015 0.0138 0.0191
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.3154 0.3968
Echinococcus multilocularis Polycystic kidney disease protein 0.0015 0.0138 0.0173
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.081 0.0767
Loa Loa (eye worm) hypothetical protein 0.0108 0.3154 0.4367
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.081 0.0767
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0036 0.081 0.1144
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0068 0.1867 0.2589
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0108 0.3154 0.3968
Loa Loa (eye worm) hypothetical protein 0.0116 0.341 0.4723
Echinococcus multilocularis potassium voltage gated channel protein 0.0108 0.3154 0.3968
Plasmodium falciparum phd finger protein, putative 0.0032 0.0686 0.831
Loa Loa (eye worm) hypothetical protein 0.0024 0.0426 0.058
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.081 0.0767

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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