TDR Targets

Basic information

Technical information

TDR Targets ID: 667818
Name: ZINC01134549
MW: 350.273 | Formula: C16H16BrNOS
H donors: 1 H acceptors: 1 LogP: 4.76 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: O=C(Nc1cc(C)cc(c1)C)CSc1ccc(cc1)Br
InChi: 1S/C16H16BrNOS/c1-11-7-12(2)9-14(8-11)18-16(19)10-20-15-5-3-13(17)4-6-15/h3-9H,10H2,1-2H3,(H,18,19)
InChiKey: UMOLAKXYZHUFDP-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0198	0.1164	0.1164
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Echinococcus granulosus	arachidonate 5 lipoxygenase	0.0115	0.0567	0.0567
Schistosoma mansoni	lipoxygenase	0.0081	0.0316	0.0316
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Echinococcus granulosus	Receptor type tyrosine protein phosphatase O	0.0053	0.0118	0.0118
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Echinococcus multilocularis	ectonucleotide	0.0198	0.1164	0.1164
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Mycobacterium leprae	hypothetical protein	0.0037	0	0.5
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0053	0.0118	0.0118
Plasmodium falciparum	GPI ethanolamine phosphate transferase 3, putative	0.0037	0	0.5
Echinococcus multilocularis	protein tyrosine phosphatase n9	0.0053	0.0118	0.0118
Schistosoma mansoni	protein tyrosine phosphatase	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Schistosoma mansoni	receptor protein tyrosine phosphatase r (pcptp1)	0.0053	0.0118	0.0118
Entamoeba histolytica	Pten 3-phosphoinositide phosphatase, putative	0.0053	0.0118	0.0231
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0053	0.0118	0.0118
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0053	0.0118	0.0118
Echinococcus multilocularis		0.0053	0.0118	0.0118
Echinococcus granulosus	neuropeptide s receptor	0.0453	0.3004	0.3004
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0061	0.0174	0.0174
Trypanosoma brucei	DNA polymerase eta, putative	0.0045	0.0058	0.0417
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Schistosoma mansoni	protein tyrosine phosphatase	0.0053	0.0118	0.0118
Loa Loa (eye worm)	phosphotyrosine protein phosphatase	0.0745	0.5119	0.5119
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Brugia malayi	Low molecular weight phosphotyrosine protein phosphatase containing protein	0.0745	0.5119	0.5119
Echinococcus multilocularis	dna polymerase eta	0.0045	0.0058	0.0058
Loa Loa (eye worm)	thrombospondin type 1 domain-containing protein	0.0507	0.3399	0.3399
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Schistosoma mansoni	protein tyrosine phosphatase non-receptor type nt1	0.1421	1	1
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0053	0.0118	0.0118
Leishmania major	DNA polymerase eta, putative	0.0045	0.0058	0.0417
Onchocerca volvulus		0.0507	0.3399	0.664
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Echinococcus granulosus	lysosomal alpha glucosidase	0.0164	0.0916	0.0916
Brugia malayi	Type I phosphodiesterase / nucleotide pyrophosphatase family protein	0.0235	0.1431	0.1431
Schistosoma mansoni	hypothetical protein	0.0507	0.3399	0.3399
Echinococcus multilocularis	lysosomal alpha glucosidase	0.0164	0.0916	0.0916
Schistosoma mansoni	protein-tyrosine phosphatase non-receptor type nt5	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Trypanosoma cruzi	tyrosine specific protein phosphatase, putative	0.0053	0.0118	0.0452
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	protein-tyrosine phosphatase 1	0.0053	0.0118	0.0118
Echinococcus granulosus	Endonuclease G	0.0141	0.0753	0.0753
Trypanosoma cruzi	DNA/RNA non-specific endonuclease protein-like, putative	0.0141	0.0753	0.5206
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Brugia malayi	hypothetical protein	0.0053	0.0118	0.0118
Echinococcus multilocularis	receptor type tyrosine protein phosphatase H	0.0053	0.0118	0.0118
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0235	0.1431	0.1431
Trypanosoma cruzi	DNA/RNA non-specific endonuclease protein-like, putative	0.0141	0.0753	0.5206
Brugia malayi	Protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Brugia malayi	hypothetical protein	0.0053	0.0118	0.0118
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Trypanosoma cruzi	endonuclease G, putative	0.0141	0.0753	0.5206
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Echinococcus granulosus	Receptor type tyrosine protein phosphatase O	0.0053	0.0118	0.0118
Schistosoma mansoni	alpha-glucosidase	0.0141	0.0751	0.0751
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0053	0.0118	0.0118
Brugia malayi	Protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Onchocerca volvulus		0.0053	0.0118	0.0231
Brugia malayi	hypothetical protein	0.0053	0.0118	0.0118
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0053	0.0118	0.0118
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Echinococcus granulosus	geminin	0.0336	0.2162	0.2162
Trypanosoma brucei	low molecular weight protein tyrosine phosphatase, putative	0.023	0.1393	1
Loa Loa (eye worm)	protein-tyrosine-phosphatase	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Schistosoma mansoni	endonuclease related	0.0141	0.0753	0.0753
Onchocerca volvulus		0.0053	0.0118	0.0231
Schistosoma mansoni	receptor protein tyrosine phosphatase n (ia2)	0.0053	0.0118	0.0118
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Toxoplasma gondii	DNA/RNA non-specific endonuclease	0.0141	0.0753	1
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0053	0.0118	0.0231
Loa Loa (eye worm)	hypothetical protein	0.0235	0.1431	0.1431
Echinococcus granulosus	receptor type tyrosine protein phosphatase zeta	0.0053	0.0118	0.0118
Brugia malayi	hypothetical protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0058	0.0058
Onchocerca volvulus		0.0053	0.0118	0.0231
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0053	0.0118	0.0118
Trypanosoma brucei	endonuclease G, putative	0.0141	0.0753	0.5406
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Onchocerca volvulus		0.0053	0.0118	0.0231
Trypanosoma cruzi	tyrosine specific protein phosphatase, putative	0.0053	0.0118	0.0452
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0053	0.0118	0.0118
Mycobacterium ulcerans	phosphotyrosine protein phosphatase PtpA	0.0745	0.5119	1
Echinococcus multilocularis	hypothetical protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0053	0.0118	0.0118
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0053	0.0118	0.0118
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0745	0.5119	1
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0053	0.0118	0.0118
Trypanosoma cruzi	tyrosine specific protein phosphatase, putative	0.0053	0.0118	0.0452
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0235	0.1431	0.2796
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Leishmania major	tyrosine specific protein phosphatase, putative	0.0053	0.0118	0.085
Giardia lamblia	Protein tyrosine phosphatase	0.0053	0.0118	0.0231
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0745	0.5119	1
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0198	0.1164	0.1164
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Brugia malayi	Protein-tyrosine phosphatase 1	0.0053	0.0118	0.0118
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Giardia lamblia	Low molecular weight protein-tyrosine-phosphatase	0.0745	0.5119	1
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0061	0.0174	0.0174
Echinococcus multilocularis	neuropeptide receptor A26	0.0453	0.3004	0.3004
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Leishmania major	hypothetical protein, conserved	0.023	0.1393	1
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0053	0.0118	0.0118
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Schistosoma mansoni	hypothetical protein	0.0336	0.2162	0.2162
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.1421	1	1
Echinococcus granulosus	neuropeptide receptor A26	0.0453	0.3004	0.3004
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0235	0.1431	0.1431
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.0794	0.5469	0.5469
Loa Loa (eye worm)	hypothetical protein	0.0235	0.1431	0.1431
Schistosoma mansoni	lipoxygenase	0.0115	0.0567	0.0567
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Loa Loa (eye worm)	dual specificity protein phosphatase CDC14B	0.0053	0.0118	0.0118
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0053	0.0118	0.0118
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0745	0.5119	1
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0745	0.5119	1
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0745	0.5119	1
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.1421	1	1
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0198	0.1164	0.1164
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.1421	1	1
Schistosoma mansoni	receptor protein tyrosine phosphatase	0.0053	0.0118	0.0118
Brugia malayi	ImpB/MucB/SamB family protein	0.0045	0.0058	0.0058
Brugia malayi	protein-tyrosine phosphatase Lar-like precursor, putative	0.0053	0.0118	0.0118
Schistosoma mansoni	DNA polymerase eta	0.0045	0.0058	0.0058
Onchocerca volvulus		0.0053	0.0118	0.0231
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Echinococcus granulosus	protein tyrosine phosphatase n9	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0053	0.0118	0.0231
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Echinococcus multilocularis	geminin	0.0336	0.2162	0.2162
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Schistosoma mansoni	aldehyde dehydrogenase	0.0061	0.0174	0.0174
Trypanosoma brucei	protein tyrosine phosphatase 1	0.0053	0.0118	0.085
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Leishmania major	DNA/RNA non-specific endonuclease-like protein	0.0141	0.0753	0.5406
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.023	0.1393	0.2549
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0235	0.1431	0.1431
Brugia malayi	Glycosyl hydrolases family 31 protein	0.0164	0.0916	0.0916
Onchocerca volvulus		0.0053	0.0118	0.0231
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Schistosoma mansoni	ectonucleotide pyrophosphatase/phosphodiesterase	0.0235	0.1431	0.1431
Brugia malayi	Thrombospondin type 1 domain containing protein	0.0507	0.3399	0.3399
Loa Loa (eye worm)	glycosyl hydrolase family 31 protein	0.0164	0.0916	0.0916
Loa Loa (eye worm)	hypothetical protein	0.0235	0.1431	0.1431
Echinococcus granulosus	dna polymerase eta	0.0045	0.0058	0.0058
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0053	0.0118	0.0118
Mycobacterium tuberculosis	Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase)	0.0516	0.3459	1
Onchocerca volvulus		0.0053	0.0118	0.0231
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0053	0.0118	0.0118
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Echinococcus granulosus	ectonucleotide	0.0198	0.1164	0.1164
Echinococcus multilocularis	lysosomal alpha glucosidase	0.0164	0.0916	0.0916
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.023	0.1393	0.2549
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0745	0.5119	1
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0053	0.0118	0.0118
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0061	0.0174	0.1248
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Schistosoma mansoni	rgs-gaip interacting protein gipc	0.0053	0.0118	0.0118
Schistosoma mansoni	hypothetical protein	0.0336	0.2162	0.2162
Leishmania major	protein-tyrosine phosphatase 1-like protein	0.0053	0.0118	0.085
Trypanosoma brucei	endonuclease G, putative	0.0141	0.0753	0.5406
Brugia malayi	Dual specificity protein phosphatase CDC14B	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Schistosoma mansoni	protein-tyrosine phosphatase n9	0.0053	0.0118	0.0118
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0061	0.0174	0.034
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0745	0.5119	1
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Onchocerca volvulus		0.0235	0.1431	0.2796
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0053	0.0118	0.0231
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Trypanosoma cruzi	hypothetical protein, conserved	0.023	0.1393	1
Echinococcus multilocularis	Endonuclease G	0.0141	0.0753	0.0753
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0745	0.5119	1
Brugia malayi	hypothetical protein	0.0053	0.0118	0.0118
Schistosoma mansoni	non-receptor protein-tyrosine phosphatase	0.0053	0.0118	0.0118
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0745	0.5119	1
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0053	0.0118	0.0118
Echinococcus multilocularis	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Echinococcus granulosus	receptor type tyrosine protein phosphatase zeta	0.0053	0.0118	0.0118
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0053	0.0118	0.0118
Trypanosoma brucei	endonuclease G, putative	0.0141	0.0753	0.5406
Schistosoma mansoni	aldehyde dehydrogenase	0.0061	0.0174	0.0174
Onchocerca volvulus		0.0053	0.0118	0.0231
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Echinococcus granulosus	ectonucleotide pyrophosphatase:phosphodiesterase	0.0235	0.1431	0.1431
Onchocerca volvulus		0.0053	0.0118	0.0231
Onchocerca volvulus		0.0053	0.0118	0.0231
Schistosoma mansoni	receptor protein tyrosine phosphatase n (ia2)	0.0053	0.0118	0.0118
Trypanosoma cruzi	hypothetical protein, conserved	0.023	0.1393	1
Echinococcus multilocularis	arachidonate 5 lipoxygenase	0.0115	0.0567	0.0567
Echinococcus multilocularis	neuropeptide s receptor	0.0453	0.3004	0.3004
Brugia malayi	endonuclease G, mitochondrial precursor	0.0141	0.0753	0.0753
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	protein tyrosine phosphatase	0.0053	0.0118	0.0118
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0061	0.0174	0.034
Trypanosoma cruzi	endonuclease G, putative	0.0141	0.0753	0.5206
Leishmania major	endonuclease G, putative	0.0141	0.0753	0.5406
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Onchocerca volvulus		0.0095	0.0417	0.0815
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0061	0.0174	0.034
Schistosoma mansoni	pcd6 interacting protein-related	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Schistosoma mansoni	alpha-glucosidase	0.0141	0.0751	0.0751
Onchocerca volvulus		0.0053	0.0118	0.0231
Onchocerca volvulus	4.1 G protein, putative homolog	0.0053	0.0118	0.0231
Schistosoma mansoni	protein tyrosine phosphatase	0.0053	0.0118	0.0118
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0053	0.0118	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0118	0.0118
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0053	0.0118	0.0118

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 667818