Detailed information for compound 702341

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 414.478 | Formula: C20H22N4O4S
  • H donors: 1 H acceptors: 4 LogP: 1.5 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCc1cnc2c(c1SCC(=O)Nc1cccc(c1)C)c(=O)n(c(=O)n2C)C
  • InChi: 1S/C20H22N4O4S/c1-12-6-5-7-14(8-12)22-15(25)11-29-17-13(10-28-4)9-21-18-16(17)19(26)24(3)20(27)23(18)2/h5-9H,10-11H2,1-4H3,(H,22,25)
  • InChiKey: ZLPIRMAFTVQJGC-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.003 0.0448 0.0404
Loa Loa (eye worm) hypothetical protein 0.0064 0.1097 0.3982
Brugia malayi hypothetical protein 0.0031 0.0465 0.1945
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0039 0.0616 0.5125
Schistosoma mansoni cpg binding protein 0.0029 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Loa Loa (eye worm) hypothetical protein 0.0015 0.015 0.0543
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0031 0.0461 0.3554
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0455 0.2547
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.003 0.0439 0.0584
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Mycobacterium tuberculosis Conserved protein 0.0064 0.1097 0.0982
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0712 0.0712
Chlamydia trachomatis lysine--tRNA ligase 0.0022 0.0287 0.0228
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0064 0.1097 0.0982
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0455 0.2547
Brugia malayi hypothetical protein 0.013 0.239 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.015 0.0543
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0099 0.1788 0.2382
Loa Loa (eye worm) latrophilin receptor protein 2 0.0027 0.0388 0.1407
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0022 0.0287 0.2621
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.003 0.0436 0.2437
Loa Loa (eye worm) phosphatidylinositol 3 0.0013 0.0111 0.0404
Onchocerca volvulus 0.0028 0.0394 0.1174
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0128 0.017
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0008 0.0016 0.0031
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.003 0.0436 0.058
Trypanosoma brucei glucose transporter 1E 0.0031 0.0455 0.4152
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0064 0.1097 0.1097
Plasmodium falciparum calcium-dependent protein kinase 5 0.003 0.0448 0.0404
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0064 0.1097 0.0982
Leishmania major protein kinase, putative 0.003 0.0448 0.3416
Echinococcus granulosus solute carrier family 22 0.0014 0.0128 0.017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Echinococcus granulosus calcium dependent protein kinase 0.0028 0.0411 0.0548
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0455 0.4152
Loa Loa (eye worm) phosphatidylinositol 3 0.0039 0.0616 0.2238
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.003 0.0448 0.1626
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.031 0.1736
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0039 0.0616 0.0821
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0184 0.1675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0422 0.2358
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0039 0.0616 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0022 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0128 0.0715
Echinococcus granulosus lysyl tRNA synthetase 0.0022 0.0287 0.0383
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0015 0.0152 0.2473
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0099 0.1788 0.2382
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.003 0.0439 0.1835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0422 0.2358
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0128 0.0464
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0128 0.0128
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Schistosoma mansoni hypothetical protein 0.0027 0.0388 0.0388
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.003 0.0439 0.0439
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Giardia lamblia Prolyl-tRNA synthetase 0.003 0.0436 0.6304
Trypanosoma brucei glucose transporter, putative 0.0031 0.0455 0.4152
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0099 0.1788 0.2382
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0712 0.2979
Schistosoma mansoni protein kinase 0.003 0.0448 0.0448
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0018 0.0216 0.1967
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.003 0.0448 0.0596
Toxoplasma gondii ABC1 family protein 0.0064 0.1097 0.2064
Onchocerca volvulus 0.0064 0.1097 0.4283
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0712 0.0948
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.003 0.0439 0.2453
Trypanosoma brucei glucose transporter, putative 0.0031 0.0455 0.4152
Schistosoma mansoni transcription factor LCR-F1 0.0031 0.0465 0.0465
Plasmodium falciparum calcium-dependent protein kinase 1 0.003 0.0448 0.0404
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0128 0.017
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Leishmania major glucose transporter, lmgt3 0.0031 0.0455 0.3492
Brugia malayi Sugar transporter family protein 0.0014 0.0128 0.0535
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0987 0.0987
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.0287 0.1608
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0013 0.0111 0.0148
Echinococcus multilocularis lysyl tRNA synthetase 0.0022 0.0287 0.0383
Brugia malayi Sugar transporter family protein 0.0014 0.0128 0.0535
Trichomonas vaginalis penicillin-binding protein, putative 0.0064 0.1097 0.6134
Loa Loa (eye worm) beta-lactamase 0.0064 0.1097 0.3982
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0128 0.0464
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.016 0.2978 0.5603
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0455 0.4152
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0016 0.0092
Echinococcus multilocularis ubiquitin specific protease 41 0.003 0.0439 0.0584
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0086 0.1535 0.6424
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0031 0.0465 0.0619
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0436 0.0436
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0461 0.2577
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.018 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0266 0.1488
Mycobacterium leprae conserved hypothetical protein 0.0064 0.1097 0.0894
Echinococcus multilocularis solute carrier family 22 0.0014 0.0128 0.017
Toxoplasma gondii target of rapamycin (TOR), putative 0.0029 0.0422 0.0793
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0422 0.2358
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0013 0.0111 0.0465
Echinococcus multilocularis solute carrier family 22 0.0014 0.0128 0.017
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0987 0.3584
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0013 0.0111 0.1013
Echinococcus granulosus ubiquitin specific protease 41 0.003 0.0439 0.0584
Brugia malayi major facilitator superfamily protein 0.0014 0.0128 0.0535
Entamoeba histolytica protein kinase, putative 0.003 0.0448 0.7266
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0111 0.0622
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0039 0.0616 0.5619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0616 0.3447
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.015 0.0199
Echinococcus granulosus solute carrier family 22 0.0014 0.0128 0.017
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0222 0.0096
Schistosoma mansoni glucose transporter 0.0014 0.0128 0.0128
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.003 0.0436 0.1824
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0987 0.0987
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.003 0.0448 0.1874
Leishmania major lysyl-tRNA synthetase, putative 0.0022 0.0287 0.1789
Toxoplasma gondii sugar transporter ST2 0.0014 0.0128 0.0241
Plasmodium vivax lysine--tRNA ligase, putative 0.0022 0.0287 0.0201
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0039 0.0616 0.0616
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0013 0.0111 0.1013
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0013 0.0111 0.0111
Brugia malayi hypothetical protein 0.0014 0.0128 0.0535
Plasmodium vivax proline--tRNA ligase, putative 0.0035 0.0532 0.051
Toxoplasma gondii histone lysine methyltransferase SET1 0.0052 0.0874 0.1645
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0128 0.1166
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Echinococcus multilocularis lysine specific demethylase 5A 0.0056 0.0957 0.1274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.035 0.1956
Brugia malayi major facilitator superfamily protein 0.0014 0.0128 0.0535
Loa Loa (eye worm) hypothetical protein 0.0064 0.1097 0.3982
Trypanosoma cruzi target of rapamycin kinase 3 0.0031 0.0461 0.4207
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.003 0.0448 0.0843
Trypanosoma brucei glucose transporter, putative 0.0031 0.0455 0.4152
Trichomonas vaginalis esterase, putative 0.0064 0.1097 0.6134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0111 0.0622
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0039 0.0616 0.5619
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0128 0.017
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0532 0.4849
Brugia malayi F/Y-rich N-terminus family protein 0.0008 0.002 0.0085
Schistosoma mansoni sugar transporter 0.0014 0.0128 0.0128
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.016 0.2978 0.3595
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0455 0.2547
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Schistosoma mansoni protein kinase 0.003 0.0448 0.0448
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0128 0.0535
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Schistosoma mansoni hypothetical protein 0.0059 0.1004 0.1004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0064 0.1097 0.4589
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0015 0.0152 0.0025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0019 0.0234 0.131
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Plasmodium falciparum protein kinase 7 0.028 0.5315 0.6542
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0064 0.1097 0.1097
Mycobacterium tuberculosis Probable esterase LipL 0.0064 0.1097 0.0982
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0712 0.0948
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0448 0.0596
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.003 0.0448 0.0404
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0455 0.4152
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0455 0.2547
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.003 0.0436 0.058
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0022 0.0082
Mycobacterium ulcerans esterase/lipase LipP 0.0064 0.1097 0.1042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0366 0.2047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0422 0.2358
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.003 0.0439 0.2453
Schistosoma mansoni glucose transport protein 0.0099 0.1788 0.1788
Schistosoma mansoni sugar transporter 0.0014 0.0128 0.0128
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0022 0.0287 0.2621
Echinococcus granulosus geminin 0.0137 0.2525 0.3363
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0407 0.7782 0.7754
Brugia malayi beta-lactamase 0.0064 0.1097 0.4589
Giardia lamblia Lysyl-tRNA synthetase 0.0022 0.0287 0.3267
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0099 0.1788 0.2382
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.015 0.0199
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0015 0.0152 0.0025
Echinococcus granulosus cpg binding protein 0.0029 0.0424 0.0565
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0016 0.0172 0.1568
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0128 0.0715
Loa Loa (eye worm) hypothetical protein 0.0086 0.1535 0.5574
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Mycobacterium tuberculosis Conserved protein 0.0064 0.1097 0.0982
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Brugia malayi Calcitonin receptor-like protein seb-1 0.0086 0.1535 0.6424
Plasmodium vivax CDK-related protein kinase 6, putative 0.0421 0.8056 1
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0521 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.015 0.0543
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0448 0.0596
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0448 0.0596
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Toxoplasma gondii protein kinase, putative 0.028 0.5315 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0056 0.0957 0.1274
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0152 0.139
Brugia malayi beta-lactamase family protein 0.0064 0.1097 0.4589
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0439 0.3999
Brugia malayi hypothetical protein 0.0014 0.0128 0.0535
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0027 0.0388 0.1621
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0448 0.0448
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0099 0.1788 0.2382
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0015 0.0152 0.139
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0532 0.4268
Entamoeba histolytica hypothetical protein 0.0031 0.0465 0.754
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0267 0.1491
Schistosoma mansoni cpg binding protein 0.0029 0.0424 0.0424
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0111 0.0622
Trypanosoma brucei sugar transporter, putative 0.0014 0.0128 0.1166
Entamoeba histolytica hypothetical protein 0.0031 0.0465 0.754
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.003 0.0448 0.0843
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0532 0.4849
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0128 0.1166
Plasmodium vivax JmjC domain containing protein 0.0015 0.015 0.0027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0015 0.0152 0.139
Loa Loa (eye worm) hypothetical protein 0.003 0.0436 0.1582
Plasmodium vivax hexose transporter 0.0099 0.1788 0.2094
Schistosoma mansoni hypothetical protein 0.0027 0.0388 0.0388
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0015 0.0152 0.0031
Onchocerca volvulus 0.0064 0.1097 0.4283
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0128 0.0241
Mycobacterium ulcerans lipase LipD 0.0064 0.1097 0.1042
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.015 0.0027
Brugia malayi hypothetical protein 0.0014 0.0128 0.0535
Loa Loa (eye worm) hypothetical protein 0.013 0.239 0.8677
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.015 0.1364
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0222 0.0096
Mycobacterium tuberculosis Conserved protein 0.0064 0.1097 0.0982
Brugia malayi latrophilin 2 splice variant baaae 0.0059 0.1004 0.4201
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.015 0.1364
Loa Loa (eye worm) hypothetical protein 0.0059 0.1004 0.3645
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0056 0.0957 0.1274
Schistosoma mansoni lysyl-tRNA synthetase 0.0022 0.0287 0.0287
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0099 0.1788 0.2382
Brugia malayi beta-lactamase family protein 0.0064 0.1097 0.4589
Loa Loa (eye worm) hypothetical protein 0.0064 0.1097 0.3982
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0058 0.0996 0.0996
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0712 0.2585
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0128 0.0715
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0027 0.0388 0.0516
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0031 0.0465 0.0619
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.003 0.0436 0.1824
Toxoplasma gondii sugar transporter ST1 0.0014 0.0128 0.0241
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.006 0.0337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0422 0.2358
Brugia malayi jmjC domain containing protein 0.0058 0.0987 0.413
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0015 0.0152 0.0553
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0013 0.0111 0.0148
Schistosoma mansoni jumonji domain containing protein 0.0015 0.015 0.015
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0086 0.1535 0.5574
Plasmodium falciparum protein kinase 6 0.0421 0.8056 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0712 0.0712
Trypanosoma brucei glucose transporter, putative 0.0031 0.0455 0.4152
Echinococcus multilocularis General substrate transporter 0.0085 0.1517 0.202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0266 0.1488
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0027 0.0388 0.0516
Schistosoma mansoni hypothetical protein 0.0137 0.2525 0.2525
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.031 0.1736
Entamoeba histolytica hypothetical protein 0.0022 0.0287 0.4664
Schistosoma mansoni hypothetical protein 0.0137 0.2525 0.2525
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0267 0.1491
Echinococcus multilocularis solute carrier family 22 0.0014 0.0128 0.017
Brugia malayi Cam kinase protein 1 0.003 0.0448 0.1874
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0015 0.0152 0.0502
Echinococcus granulosus phd:f box containing protein 0.0015 0.015 0.0199
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0455 0.4152
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0394 0.1429
Brugia malayi jmjC domain containing protein 0.0015 0.015 0.0626
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0039 0.0616 0.5125
Schistosoma mansoni jumonji domain containing protein 0.0056 0.0957 0.0957
Brugia malayi lysyl-tRNA synthetase 0.0022 0.0287 0.1203
Plasmodium falciparum mitogen-activated protein kinase 2 0.016 0.2978 0.3595
Entamoeba histolytica hypothetical protein 0.0031 0.0465 0.754
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0267 0.1491
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0012 0.0094 0.0342
Plasmodium vivax calcium-dependent protein kinase, putative 0.003 0.0448 0.0404
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0064 0.1097 0.3982
Schistosoma mansoni lysyl-tRNA synthetase 0.0022 0.0287 0.0287
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0022 0.0287 0.0228
Trypanosoma cruzi hexose transporter 0.0031 0.0455 0.4152
Mycobacterium tuberculosis Probable lipase LipD 0.0064 0.1097 0.0982
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0439 0.3999
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0128 0.0067
Brugia malayi jmjC domain containing protein 0.0015 0.015 0.0626
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0015 0.0152 0.0419
Loa Loa (eye worm) hypothetical protein 0.0064 0.1097 0.3982
Schistosoma mansoni hypothetical protein 0.0027 0.0388 0.0388
Mycobacterium ulcerans hypothetical protein 0.0064 0.1097 0.1042
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0521 1 1
Plasmodium falciparum calcium-dependent protein kinase 3 0.003 0.0448 0.0404
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0015 0.0152 0.0092
Leishmania major hypothetical protein, conserved 0.0014 0.0128 0.017
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0532 0.4268
Echinococcus granulosus solute carrier family 22 0.0014 0.0128 0.017
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.015 0.0199
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.015 0.0543
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0015 0.0152 0.0203
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0448 0.0596
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0128 0.0535
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0439 0.3999
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.003 0.0439 0.6362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0461 0.2577
Leishmania major glucose transporter, lmgt2 0.0031 0.0455 0.3492
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0022 0.0287 0.0066
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.0987 0.1315
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0039 0.0616 0.5619
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Echinococcus granulosus dnaJ subfamily B 0.0393 0.7509 1
Toxoplasma gondii exonuclease III APE 0.0015 0.0152 0.0287
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0015 0.0152 0.0031
Echinococcus multilocularis cpg binding protein 0.0029 0.0424 0.0565
Schistosoma mansoni protein kinase 0.003 0.0448 0.0448
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0448 0.0596
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0422 0.2358
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0128 0.0715
Schistosoma mansoni ap endonuclease 0.0015 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.003 0.0436 0.1582
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Mycobacterium tuberculosis Probable lipase LipE 0.0064 0.1097 0.0982
Onchocerca volvulus 0.013 0.239 1
Entamoeba histolytica protein kinase, putative 0.003 0.0448 0.7266
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Schistosoma mansoni hypothetical protein 0.0393 0.7509 0.7509
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0448 0.0596
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.003 0.0439 0.0584
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0128 0.0715
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0027 0.0388 0.0516
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.0521 1 1
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0128 0.1166
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0455 0.4152
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.003 0.0448 0.4083
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.003 0.0439 0.0584
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0128 0.0535
Toxoplasma gondii facilitative glucose transporter GT1 0.0099 0.1788 0.3365
Mycobacterium leprae Probable lipase LipE 0.0064 0.1097 0.0894
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0128 0.017
Mycobacterium ulcerans sugar transporter 0.0014 0.0128 0.0067
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0039 0.0616 0.0821
Trypanosoma brucei glucose transporter, putative 0.0031 0.0455 0.4152
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0448 0.0596
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.003 0.0448 0.0843
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0306 0.1711
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0128 0.1166
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0712 0.0712
Trypanosoma cruzi hypothetical protein, conserved 0.0064 0.1097 1
Brugia malayi jmjC domain containing protein 0.0015 0.015 0.0626
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.003 0.0436 0.0218
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.003 0.0436 0.7071
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0712 0.0948
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0267 0.1491
Loa Loa (eye worm) hypothetical protein 0.0015 0.015 0.0543
Echinococcus multilocularis phd:f box containing protein 0.0015 0.015 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0532 0.4849
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0128 0.0715
Loa Loa (eye worm) sugar transporter 0.0014 0.0128 0.0464
Plasmodium vivax hypothetical protein, conserved 0.0064 0.1097 0.1222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0306 0.1711
Echinococcus granulosus General substrate transporter 0.0085 0.1517 0.202
Trypanosoma brucei glucose transporter, putative 0.0031 0.0455 0.4152
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0439 0.2453
Echinococcus multilocularis GPCR, family 2 0.0027 0.0388 0.0516
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0505 0.2825
Leishmania major glucose transporter, lmgt1 0.0031 0.0455 0.3492
Mycobacterium tuberculosis Probable hydrolase 0.0064 0.1097 0.0982
Leishmania major hypothetical protein, conserved 0.0015 0.015 0.0391
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0128 0.0715
Echinococcus multilocularis solute carrier family 22 0.0014 0.0128 0.017
Giardia lamblia GTOR 0.0039 0.0616 1
Schistosoma mansoni sugar transporter 0.0014 0.0128 0.0128
Brugia malayi Sugar transporter family protein 0.0099 0.1788 0.7482
Schistosoma mansoni cpg binding protein 0.0028 0.0394 0.0394
Plasmodium falciparum calcium-dependent protein kinase 4 0.003 0.0448 0.0404
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0455 0.3492
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Trypanosoma brucei glucose transporter, putative 0.0031 0.0455 0.4152
Loa Loa (eye worm) hypothetical protein 0.0064 0.1097 0.3982
Loa Loa (eye worm) hypothetical protein 0.003 0.0439 0.1592
Echinococcus granulosus beta LACTamase domain containing family member 0.0064 0.1097 0.1461
Schistosoma mansoni phd/f-box containing protein 0.0015 0.015 0.015
Echinococcus granulosus GPCR family 2 0.0027 0.0388 0.0516
Loa Loa (eye worm) sugar transporter 0.0099 0.1788 0.6492
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.003 0.0439 0.3322
Trypanosoma cruzi hypothetical protein, conserved 0.0064 0.1097 1
Trichomonas vaginalis D-aminoacylase, putative 0.0064 0.1097 0.6134
Brugia malayi jmjC domain containing protein 0.0056 0.0957 0.4002
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0128 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.031 0.1736
Trypanosoma brucei glucose transporter 2A 0.0031 0.0455 0.4152
Trichomonas vaginalis CAMK family protein kinase 0.003 0.0448 0.2504
Mycobacterium ulcerans beta-lactamase 0.0064 0.1097 0.1042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0111 0.0622
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.015 0.015
Trichomonas vaginalis penicillin-binding protein, putative 0.0064 0.1097 0.6134
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0461 0.2577
Echinococcus multilocularis calcium dependent protein kinase 0.0028 0.0411 0.0548
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.015 0.0282
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.015 0.0282
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0013 0.0111 0.1013
Toxoplasma gondii lysine-tRNA ligase 0.0022 0.0287 0.0541
Echinococcus granulosus solute carrier family 22 0.0014 0.0128 0.017
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.015 0.1364
Loa Loa (eye worm) hypothetical protein 0.0064 0.1097 0.3982
Treponema pallidum replicative DNA helicase (dnaB) 0.0521 1 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.015 0.0199
Loa Loa (eye worm) hypothetical protein 0.0008 0.0016 0.006
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0455 0.2547
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0035 0.0532 0.1001
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0436 0.0436
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0099 0.1788 0.2382
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Echinococcus multilocularis dnaJ subfamily B 0.0393 0.7509 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0031 0.0461 0.4207
Schistosoma mansoni hypothetical protein 0.0099 0.1788 0.1788
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0461 0.2577
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0022 0.003
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0455 0.2547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0266 0.1488
Trypanosoma brucei glucose transporter, putative 0.0031 0.0455 0.4152
Brugia malayi CXXC zinc finger family protein 0.0028 0.0394 0.1646
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0064 0.1097 0.1042
Loa Loa (eye worm) hypothetical protein 0.0022 0.0287 0.1044
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.1788 1
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0521 1 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0064 0.1097 0.1461
Toxoplasma gondii sugar transporter ST3 0.0014 0.0128 0.0241
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.003 0.0439 0.0584
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0015 0.0152 0.0203
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0022 0.0287 0.0228
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.015 0.015
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.003 0.0439 0.7117
Echinococcus multilocularis geminin 0.0137 0.2525 0.3363
Trichomonas vaginalis ap endonuclease, putative 0.0015 0.0152 0.0852
Plasmodium falciparum proline--tRNA ligase 0.0035 0.0532 0.051
Trichomonas vaginalis ap endonuclease, putative 0.0015 0.0152 0.0852
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0128 0.0067
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0039 0.0616 1
Plasmodium falciparum calcium-dependent protein kinase 2 0.003 0.0448 0.0404
Plasmodium falciparum lysine--tRNA ligase 0.0022 0.0287 0.0201
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0455 0.4152
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0039 0.0616 0.5619
Schistosoma mansoni hypothetical protein 0.0027 0.0388 0.0388
Schistosoma mansoni glucose transport protein 0.0099 0.1788 0.1788
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0422 0.2358
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Leishmania major hypothetical protein, conserved 0.0064 0.1097 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.015 0.0543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0461 0.2577
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Brugia malayi exodeoxyribonuclease III family protein 0.0015 0.0152 0.0638
Schistosoma mansoni hypothetical protein 0.0031 0.0465 0.0465
Loa Loa (eye worm) hypothetical protein 0.003 0.0448 0.1626
Schistosoma mansoni glucose transport protein 0.0099 0.1788 0.1788
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0039 0.0616 0.2579
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0327 0.1188
Onchocerca volvulus 0.0064 0.1097 0.4283
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0099 0.1788 0.2382
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.018 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0111 0.0622
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0712 0.0948
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0616 0.3447
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0128 0.0067
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.015 0.0199
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0128 0.0715
Trichomonas vaginalis D-aminoacylase, putative 0.0064 0.1097 0.6134
Loa Loa (eye worm) hypothetical protein 0.0014 0.0128 0.0464
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.003 0.0448 0.0404
Brugia malayi Latrophilin receptor protein 2 0.0027 0.0388 0.1621
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0128 0.0715
Schistosoma mansoni ap endonuclease 0.0015 0.0152 0.0152
Schistosoma mansoni sugar transporter 0.0014 0.0128 0.0128
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0027 0.0388 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0455 0.2547
Brugia malayi jmjC domain containing protein 0.0015 0.015 0.0626
Loa Loa (eye worm) twinkle helicase 0.0149 0.2754 1
Schistosoma mansoni protein phosphatase 2C 0.0015 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0388 0.1407
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.003 0.0448 0.1626
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0064 0.1097 0.0982
Plasmodium falciparum hexose transporter 0.0099 0.1788 0.2094
Trichomonas vaginalis D-aminoacylase, putative 0.0064 0.1097 0.6134
Schistosoma mansoni Replicative DNA helicase 0.0521 1 1
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.015 0.0199
Entamoeba histolytica hypothetical protein 0.0031 0.0465 0.754
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0013 0.0111 0.1013
Treponema pallidum exodeoxyribonuclease (exoA) 0.0015 0.0152 0.0092
Trypanosoma brucei hypothetical protein, conserved 0.0064 0.1097 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.003 0.0439 0.0439
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0616 0.3447

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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