Detailed information for compound 784169

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 320.181 | Formula: C15H14BrNO2
  • H donors: 1 H acceptors: 1 LogP: 3.89 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(C=Nc2ccc(cc2)C)cc(c1O)Br
  • InChi: 1S/C15H14BrNO2/c1-10-3-5-12(6-4-10)17-9-11-7-13(16)15(18)14(8-11)19-2/h3-9,18H,1-2H3/b17-9+
  • InChiKey: FPJYXRVLXXYZOX-RQZCQDPDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii ABC1 family protein 0.0038 0.0211 0.0143
Loa Loa (eye worm) histone methyltransferase 0.0023 0.009 0.009
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0141
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0055
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0051 0.0051
Brugia malayi beta-lactamase 0.0038 0.0211 0.0211
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0103 0.0103
Brugia malayi MH1 domain containing protein 0.0018 0.0051 0.0051
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0069 0.0069
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0209 0.0141
Schistosoma mansoni hypothetical protein 0.0068 0.0441 0.0441
Echinococcus multilocularis Smad4 0.0018 0.0051 0.0051
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0051 0.0051
Plasmodium vivax protein-S-isoprenylcysteine O-methyltransferase, putative 0.1295 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0103 0.0112
Brugia malayi hypothetical protein 0.007 0.0462 0.0462
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.026 0.026
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0209 0.0209
Echinococcus multilocularis smad 0.0018 0.0051 0.0051
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0103 0.0034
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0209 0.0209
Brugia malayi Ets-domain containing protein 0.0076 0.0506 0.0506
Entamoeba histolytica hypothetical protein 0.007 0.0462 0.0396
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.033 0.0276
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0211 0.0143
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0211 0.0211
Entamoeba histolytica prenyl cysteine carboxyl methyltransferase, putative 0.1295 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0055
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0565 0.4318 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0103 0.013
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0024 0.0103 0.0103
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0069 0.5
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0093 0.0639 0.0639
Trichomonas vaginalis set domain proteins, putative 0.0729 0.5591 0.558
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0211 0.0143
Echinococcus granulosus microtubule associated protein 2 0.0764 0.5869 0.5869
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0069 0.005
Schistosoma mansoni hypothetical protein 0.0886 0.6818 0.6818
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0061 0.0061
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.0441 0.0441
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0055 0.5
Brugia malayi follicle stimulating hormone receptor 0.0237 0.1762 0.1762
Loa Loa (eye worm) hypothetical protein 0.0214 0.1581 0.1581
Loa Loa (eye worm) hypothetical protein 0.0065 0.042 0.042
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.1295 1 1
Echinococcus granulosus cpg binding protein 0.0066 0.0427 0.0427
Schistosoma mansoni hypothetical protein 0.0146 0.1053 0.1053
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.181 0.4126
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0069 0.0045
Giardia lamblia Isoprenylcysteine carboxyl methyltransferase 0.1295 1 1
Onchocerca volvulus 0.0104 0.0721 0.1125
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0211 0.0211
Schistosoma mansoni cellular tumor antigen P53 0.0104 0.0721 0.0721
Brugia malayi Smad1 0.0018 0.0051 0.0051
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.064 0.4903 0.4903
Echinococcus granulosus Smad4 0.0018 0.0051 0.0051
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0103 0.0112
Trypanosoma cruzi prenyl protein specific carboxyl methyltransferase, putative 0.1295 1 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0103 0.0103
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.1295 1 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0103 0.0034
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.001 0.001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0103 0.0034
Schistosoma mansoni protein-s-isoprenylcysteine o-methyltransferase 0.1295 1 1
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0211 0.0365
Echinococcus multilocularis 0.1295 1 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0069 0.0032
Trichomonas vaginalis esterase, putative 0.0038 0.0211 0.0187
Mycobacterium ulcerans lipase LipD 0.0038 0.0211 0.0365
Brugia malayi Ets-domain containing protein 0.0076 0.0506 0.0506
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0051 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0639 0.0639
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.01 0.01
Brugia malayi beta-lactamase family protein 0.0038 0.0211 0.0211
Schistosoma mansoni cpg binding protein 0.0066 0.0427 0.0427
Schistosoma mansoni inositol monophosphatase 0.0038 0.0209 0.0209
Echinococcus granulosus dnaJ subfamily B 0.0886 0.6818 0.6818
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.0441 0.0441
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0462 0.0462
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0055
Brugia malayi MH1 domain containing protein 0.0018 0.0051 0.0051
Onchocerca volvulus 0.0062 0.0399 0.0539
Loa Loa (eye worm) transcription factor SMAD2 0.0257 0.1917 0.1917
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0088 0.0088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.026 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0211 0.0143
Onchocerca volvulus 0.0038 0.0211 0.0196
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0639 0.0639
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0211 0.0382
Loa Loa (eye worm) hypothetical protein 0.0104 0.0721 0.0721
Brugia malayi MH2 domain containing protein 0.0257 0.1917 0.1917
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0209 0.0185
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0169 0.1227 0.1227
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.026 0.026
Schistosoma mansoni cpg binding protein 0.0062 0.0399 0.0399
Brugia malayi Calcitonin receptor-like protein seb-1 0.0214 0.1581 0.1581
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0103 0.0103
Toxoplasma gondii isoprenylcysteine carboxyl methyltransferase (icmt) family protein 0.1295 1 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0051 0.0051
Leishmania major prenyl protein specific carboxyl methyltransferase, putative 0.1295 1 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0441 0.0441
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0103 0.0034
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.033 0.0262
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.0441 0.0441
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0141
Mycobacterium tuberculosis Conserved protein 0.0038 0.0211 0.0382
Schistosoma mansoni ap endonuclease 0.002 0.0069 0.0069
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.033 0.0262
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0211 0.0382
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0055 0.0018
Brugia malayi hypothetical protein 0.0053 0.033 0.033
Brugia malayi Latrophilin receptor protein 2 0.0068 0.0441 0.0441
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.026 0.026
Brugia malayi CXXC zinc finger family protein 0.0062 0.0399 0.0399
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0211 0.0211
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0211 0.0187
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0051 0.0051
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0061 0.0061
Schistosoma mansoni Smad4 0.0018 0.0051 0.0051
Echinococcus multilocularis GA binding protein alpha chain 0.0076 0.0506 0.0506
Brugia malayi MH2 domain containing protein 0.0018 0.0051 0.0051
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0211 0.0382
Entamoeba histolytica hypothetical protein 0.007 0.0462 0.0396
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0211 0.0382
Loa Loa (eye worm) MH2 domain-containing protein 0.0257 0.1917 0.1917
Trypanosoma cruzi prenyl protein specific carboxyl methyltransferase, putative 0.1295 1 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0103 0.0034
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0211 0.0187
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.026 0.026
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0859 0.0795
Echinococcus multilocularis tumor protein p63 0.0708 0.5426 0.5426
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0103 0.0112
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.01 0.01
Schistosoma mansoni smad1 5 8 and 0.0018 0.0051 0.0051
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.1053 0.1053
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0069 0.0069
Echinococcus multilocularis geminin 0.0169 0.1227 0.1227
Mycobacterium ulcerans hypothetical protein 0.0565 0.4318 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.0441 0.0441
Echinococcus granulosus histone lysine methyltransferase setb 0.0093 0.0639 0.0639
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.1762 0.1762
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.033 0.0276
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0211 0.0187
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.1295 1 1
Echinococcus granulosus tumor protein p63 0.0708 0.5426 0.5426
Loa Loa (eye worm) Smad1 0.0018 0.0051 0.0051
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0211 0.0382
Mycobacterium tuberculosis Conserved protein 0.0038 0.0211 0.0382
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.0639 0.0639
Echinococcus multilocularis GPCR, family 2 0.0068 0.0441 0.0441
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0103 0.013
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0103 0.0112
Schistosoma mansoni microtubule-associated protein tau 0.0764 0.5869 0.5869
Schistosoma mansoni ets-related 0.0231 0.1711 0.1711
Plasmodium falciparum protein-S-isoprenylcysteine O-methyltransferase, putative 0.1295 1 1
Schistosoma mansoni cpg binding protein 0.0066 0.0427 0.0427
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.026 0.026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0211 0.0211
Brugia malayi Inositol-1 0.0038 0.0209 0.0209
Schistosoma mansoni gabp alpha 0.0076 0.0506 0.0506
Echinococcus granulosus protein S isoprenylcysteine O methyltransferase 0.1295 1 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0103 0.0034
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0141
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0103 0.0112
Mycobacterium ulcerans hypothetical protein 0.0024 0.0103 0.0112
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0103 0.0112
Brugia malayi beta-lactamase family protein 0.0038 0.0211 0.0211
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0211 0.0382
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0927 0.7133 0.7133
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.009 0.009
Entamoeba histolytica prenyl cysteine carboxyl methyltransferase, putative 0.1295 1 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0209 0.0185
Schistosoma mansoni hypothetical protein 0.0068 0.0441 0.0441
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0178 0.0305
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.0639 0.0574
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0211 0.0156
Mycobacterium ulcerans beta-lactamase 0.0038 0.0211 0.0365
Loa Loa (eye worm) fli-1 protein 0.0231 0.1711 0.1711
Mycobacterium ulcerans hypothetical protein 0.0038 0.0211 0.0365
Echinococcus granulosus smad 0.0018 0.0051 0.0051
Brugia malayi Fli-1 protein 0.0231 0.1711 0.1711
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0211 0.0365
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0135 0.0969 0.0969
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0103 0.0112
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.026 0.026
Entamoeba histolytica hypothetical protein 0.007 0.0462 0.0396
Brugia malayi hypothetical protein 0.0034 0.0182 0.0182
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0209 0.0185
Onchocerca volvulus 0.0093 0.0639 0.0976
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0209 1
Mycobacterium leprae Probable lipase LipE 0.0038 0.0211 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0211 0.0211
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0211 0.0187
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0211 0.0187
Schistosoma mansoni hypothetical protein 0.007 0.0462 0.0462
Schistosoma mansoni hypothetical protein 0.0068 0.0441 0.0441
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0146 0.1053 0.1053
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.009 0.009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.026 0.026
Entamoeba histolytica hypothetical protein 0.007 0.0462 0.0396
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0141
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0069 0.0045
Schistosoma mansoni smad1 5 8 and 0.0018 0.0051 0.0051
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0019 0.0061 0.0061
Onchocerca volvulus 0.0038 0.0211 0.0196
Trypanosoma brucei prenyl protein specific carboxyl methyltransferase 0.1295 1 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0462 0.0462
Brugia malayi MH2 domain containing protein 0.0018 0.0051 0.0051
Schistosoma mansoni hypothetical protein 0.0068 0.0441 0.0441
Schistosoma mansoni ap endonuclease 0.002 0.0069 0.0069
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0076 0.0506 0.0506
Onchocerca volvulus 0.0729 0.5591 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0209 0.036
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0399 0.0399
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0214 0.1581 0.1581
Echinococcus multilocularis microtubule associated protein 2 0.0764 0.5869 0.5869
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0211 0.0382
Echinococcus granulosus geminin 0.0169 0.1227 0.1227
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0211 0.0211
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0069 0.0014
Loa Loa (eye worm) protein-S isoprenylcysteine O-methyltransferase 0.1295 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0093 0.0639 0.0639
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0024 0.0103 0.0103
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0051 0.0051
Leishmania major hypothetical protein, conserved 0.0053 0.033 0.0262
Plasmodium vivax SET domain protein, putative 0.0093 0.0639 0.0587
Echinococcus granulosus mixed lineage leukemia protein mll 0.0019 0.0061 0.0061
Schistosoma mansoni smad 0.0018 0.0051 0.0051
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.0441 0.0441
Schistosoma mansoni hypothetical protein 0.0169 0.1227 0.1227
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.026 0.026
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0209 0.0141
Leishmania major hypothetical protein, conserved 0.0038 0.0211 0.0143
Schistosoma mansoni hypothetical protein 0.0024 0.01 0.01
Brugia malayi Pre-SET motif family protein 0.0093 0.0639 0.0639
Onchocerca volvulus 0.0038 0.0211 0.0196
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0178 0.6938
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.033 0.0262
Echinococcus multilocularis dnaJ subfamily B 0.0886 0.6818 0.6818
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0088 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0069 0.0014
Mycobacterium tuberculosis Conserved protein 0.0038 0.0211 0.0382
Echinococcus granulosus GA binding protein alpha chain 0.0076 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0053 0.033 0.033
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0211 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0462 0.0462
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.0441 0.0441
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0639 0.0639
Echinococcus multilocularis cpg binding protein 0.0066 0.0427 0.0427
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.033 0.0262
Schistosoma mansoni smad1 5 8 and 0.0018 0.0051 0.0051
Loa Loa (eye worm) beta-lactamase 0.0038 0.0211 0.0211
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0214 0.1581 0.1581
Loa Loa (eye worm) inositol-1 0.0038 0.0209 0.0209
Brugia malayi Pre-SET motif family protein 0.064 0.4903 0.4903
Echinococcus granulosus GPCR family 2 0.0068 0.0441 0.0441
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0093 0.0639 0.0639
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.033 0.0276
Schistosoma mansoni inositol monophosphatase 0.0038 0.0209 0.0209

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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