Detailed information for compound 784169

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 320.181 | Formula: C15H14BrNO2
  • H donors: 1 H acceptors: 1 LogP: 3.89 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(C=Nc2ccc(cc2)C)cc(c1O)Br
  • InChi: 1S/C15H14BrNO2/c1-10-3-5-12(6-4-10)17-9-11-7-13(16)15(18)14(8-11)19-2/h3-9,18H,1-2H3/b17-9+
  • InChiKey: FPJYXRVLXXYZOX-RQZCQDPDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0886 0.6818 0.6818
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0103 0.0103
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0462 0.0462
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0211 0.0211
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.0441 0.0441
Toxoplasma gondii isoprenylcysteine carboxyl methyltransferase (icmt) family protein 0.1295 1 1
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0211 0.0382
Schistosoma mansoni hypothetical protein 0.0169 0.1227 0.1227
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0055
Brugia malayi Ets-domain containing protein 0.0076 0.0506 0.0506
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0103 0.0112
Brugia malayi CXXC zinc finger family protein 0.0062 0.0399 0.0399
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0141
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0061 0.0061
Brugia malayi Pre-SET motif family protein 0.0093 0.0639 0.0639
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0069 0.0069
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0088 0.0088
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0211 1
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.033 0.0276
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0103 0.0034
Echinococcus granulosus protein S isoprenylcysteine O methyltransferase 0.1295 1 1
Loa Loa (eye worm) inositol-1 0.0038 0.0209 0.0209
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0093 0.0639 0.0639
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0141
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0055
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0211 0.0187
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.033 0.0262
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0103 0.0034
Echinococcus multilocularis cpg binding protein 0.0066 0.0427 0.0427
Entamoeba histolytica hypothetical protein 0.007 0.0462 0.0396
Echinococcus multilocularis smad 0.0018 0.0051 0.0051
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0069 0.005
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0211 0.0156
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.0639 0.0639
Echinococcus granulosus GPCR family 2 0.0068 0.0441 0.0441
Echinococcus multilocularis geminin 0.0169 0.1227 0.1227
Trypanosoma cruzi prenyl protein specific carboxyl methyltransferase, putative 0.1295 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0055
Loa Loa (eye worm) MH2 domain-containing protein 0.0257 0.1917 0.1917
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.181 0.4126
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0209 0.0141
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.1295 1 1
Schistosoma mansoni ap endonuclease 0.002 0.0069 0.0069
Onchocerca volvulus 0.0093 0.0639 0.0976
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0211 0.0187
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0211 0.0382
Brugia malayi MH2 domain containing protein 0.0018 0.0051 0.0051
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0141
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0093 0.0639 0.0639
Echinococcus granulosus microtubule associated protein 2 0.0764 0.5869 0.5869
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0069 0.0069
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.033 0.0262
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0211 0.0211
Trypanosoma cruzi prenyl protein specific carboxyl methyltransferase, putative 0.1295 1 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0069 0.0032
Echinococcus granulosus mixed lineage leukemia protein mll 0.0019 0.0061 0.0061
Brugia malayi beta-lactamase family protein 0.0038 0.0211 0.0211
Onchocerca volvulus 0.0038 0.0211 0.0196
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0069 0.0045
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.0639 0.0574
Schistosoma mansoni inositol monophosphatase 0.0038 0.0209 0.0209
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0209 0.0185
Echinococcus multilocularis 0.1295 1 1
Schistosoma mansoni hypothetical protein 0.0068 0.0441 0.0441
Mycobacterium tuberculosis Conserved protein 0.0038 0.0211 0.0382
Loa Loa (eye worm) hypothetical protein 0.0146 0.1053 0.1053
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0462 0.0462
Schistosoma mansoni Smad4 0.0018 0.0051 0.0051
Echinococcus multilocularis GA binding protein alpha chain 0.0076 0.0506 0.0506
Entamoeba histolytica prenyl cysteine carboxyl methyltransferase, putative 0.1295 1 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0103 0.0034
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0069 0.5
Mycobacterium ulcerans hypothetical protein 0.0038 0.0211 0.0365
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0069 0.0069
Mycobacterium ulcerans beta-lactamase 0.0038 0.0211 0.0365
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0051 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0639 0.0639
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.1295 1 1
Brugia malayi hypothetical protein 0.007 0.0462 0.0462
Loa Loa (eye worm) hypothetical protein 0.0065 0.042 0.042
Schistosoma mansoni cellular tumor antigen P53 0.0104 0.0721 0.0721
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.01 0.01
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.0441 0.0441
Trichomonas vaginalis esterase, putative 0.0038 0.0211 0.0187
Brugia malayi Pre-SET motif family protein 0.064 0.4903 0.4903
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.026 0.026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.026 0.026
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0103 0.0034
Echinococcus granulosus cpg binding protein 0.0066 0.0427 0.0427
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0019 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.007 0.0462 0.0462
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0069 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0639 0.0639
Brugia malayi MH1 domain containing protein 0.0018 0.0051 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0103 0.0103
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0051 0.0051
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.064 0.4903 0.4903
Brugia malayi beta-lactamase 0.0038 0.0211 0.0211
Mycobacterium ulcerans hypothetical protein 0.0024 0.0103 0.0112
Brugia malayi Latrophilin receptor protein 2 0.0068 0.0441 0.0441
Loa Loa (eye worm) fli-1 protein 0.0231 0.1711 0.1711
Brugia malayi Inositol-1 0.0038 0.0209 0.0209
Brugia malayi Smad1 0.0018 0.0051 0.0051
Schistosoma mansoni ets-related 0.0231 0.1711 0.1711
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0135 0.0969 0.0969
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.0441 0.0441
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0076 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0214 0.1581 0.1581
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0103 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0639 0.0639
Schistosoma mansoni gabp alpha 0.0076 0.0506 0.0506
Schistosoma mansoni cpg binding protein 0.0066 0.0427 0.0427
Schistosoma mansoni hypothetical protein 0.0068 0.0441 0.0441
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0211 0.0211
Schistosoma mansoni inositol monophosphatase 0.0038 0.0209 0.0209
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0051 0.0051
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.009 0.009
Loa Loa (eye worm) histone methyltransferase 0.0023 0.009 0.009
Mycobacterium tuberculosis Conserved protein 0.0038 0.0211 0.0382
Loa Loa (eye worm) hypothetical protein 0.0024 0.0103 0.0103
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.026 0.026
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0141
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0051 0.0051
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0103 0.0112
Leishmania major hypothetical protein, conserved 0.0053 0.033 0.0262
Brugia malayi Fli-1 protein 0.0231 0.1711 0.1711
Schistosoma mansoni cpg binding protein 0.0062 0.0399 0.0399
Echinococcus granulosus histone lysine methyltransferase setb 0.0093 0.0639 0.0639
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0859 0.0795
Schistosoma mansoni protein-s-isoprenylcysteine o-methyltransferase 0.1295 1 1
Loa Loa (eye worm) transcription factor SMAD2 0.0257 0.1917 0.1917
Leishmania major prenyl protein specific carboxyl methyltransferase, putative 0.1295 1 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0103 0.0103
Entamoeba histolytica hypothetical protein 0.007 0.0462 0.0396
Plasmodium vivax protein-S-isoprenylcysteine O-methyltransferase, putative 0.1295 1 1
Echinococcus granulosus GA binding protein alpha chain 0.0076 0.0506 0.0506
Brugia malayi beta-lactamase family protein 0.0038 0.0211 0.0211
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0211 0.0382
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0055
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0211 0.0382
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0211 0.0365
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0211 0.0143
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0051 0.0051
Echinococcus multilocularis dnaJ subfamily B 0.0886 0.6818 0.6818
Loa Loa (eye worm) beta-lactamase 0.0038 0.0211 0.0211
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0211 0.0143
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0178 0.6938
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.026 0.026
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0103 0.013
Echinococcus multilocularis tumor protein p63 0.0708 0.5426 0.5426
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.009 0.009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0462 0.0462
Loa Loa (eye worm) hypothetical protein 0.0104 0.0721 0.0721
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0209 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0103 0.0103
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0211 0.0211
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.033 0.0276
Onchocerca volvulus 0.0038 0.0211 0.0196
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.033 0.0276
Entamoeba histolytica hypothetical protein 0.007 0.0462 0.0396
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0211 0.0187
Plasmodium falciparum protein-S-isoprenylcysteine O-methyltransferase, putative 0.1295 1 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0211 0.0382
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0211
Echinococcus multilocularis Smad4 0.0018 0.0051 0.0051
Schistosoma mansoni hypothetical protein 0.0024 0.01 0.01
Echinococcus multilocularis microtubule associated protein 2 0.0764 0.5869 0.5869
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0214 0.1581 0.1581
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.033 0.0262
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.1053 0.1053
Echinococcus multilocularis GPCR, family 2 0.0068 0.0441 0.0441
Giardia lamblia Isoprenylcysteine carboxyl methyltransferase 0.1295 1 1
Onchocerca volvulus 0.0729 0.5591 1
Schistosoma mansoni smad1 5 8 and 0.0018 0.0051 0.0051
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0055 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.026 0.026
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0103 0.0112
Loa Loa (eye worm) hypothetical protein 0.0093 0.0639 0.0639
Entamoeba histolytica hypothetical protein 0.007 0.0462 0.0396
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0211 0.0365
Mycobacterium ulcerans lipase LipD 0.0038 0.0211 0.0365
Loa Loa (eye worm) Smad1 0.0018 0.0051 0.0051
Brugia malayi MH2 domain containing protein 0.0257 0.1917 0.1917
Schistosoma mansoni cpg binding protein 0.0066 0.0427 0.0427
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0209 0.0185
Trypanosoma brucei prenyl protein specific carboxyl methyltransferase 0.1295 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0103 0.0112
Echinococcus granulosus smad 0.0018 0.0051 0.0051
Echinococcus granulosus geminin 0.0169 0.1227 0.1227
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0209 0.0185
Brugia malayi Calcitonin receptor-like protein seb-1 0.0214 0.1581 0.1581
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.033 0.0262
Brugia malayi Ets-domain containing protein 0.0076 0.0506 0.0506
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.01 0.01
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0399 0.0399
Schistosoma mansoni smad1 5 8 and 0.0018 0.0051 0.0051
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0103 0.013
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0055 0.5
Brugia malayi hypothetical protein 0.0034 0.0182 0.0182
Echinococcus granulosus Smad4 0.0018 0.0051 0.0051
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0069 0.0045
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0565 0.4318 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0061 0.0061
Echinococcus granulosus tumor protein p63 0.0708 0.5426 0.5426
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.026 0.026
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0103 0.0112
Mycobacterium leprae Probable lipase LipE 0.0038 0.0211 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.0441 0.0441
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0103 0.0112
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0211 0.0211
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0209 0.0209
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0178 0.0305
Brugia malayi MH2 domain containing protein 0.0018 0.0051 0.0051
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0211 0.0211
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0103 0.0034
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.026 0.026
Mycobacterium tuberculosis Conserved protein 0.0038 0.0211 0.0382
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0927 0.7133 0.7133
Schistosoma mansoni hypothetical protein 0.0146 0.1053 0.1053
Toxoplasma gondii ABC1 family protein 0.0038 0.0211 0.0143
Schistosoma mansoni ap endonuclease 0.002 0.0069 0.0069
Onchocerca volvulus 0.0104 0.0721 0.1125
Mycobacterium ulcerans hypothetical protein 0.0565 0.4318 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0088 0.0602 0.0602
Brugia malayi MH1 domain containing protein 0.0018 0.0051 0.0051
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.0441 0.0441
Schistosoma mansoni microtubule-associated protein tau 0.0764 0.5869 0.5869
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0103 0.0112
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0069 0.0014
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0211 0.0382
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0211 0.0143
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0103 0.0103
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.026 0.026
Entamoeba histolytica prenyl cysteine carboxyl methyltransferase, putative 0.1295 1 1
Onchocerca volvulus 0.0062 0.0399 0.0539
Echinococcus granulosus dnaJ subfamily B 0.0886 0.6818 0.6818
Brugia malayi follicle stimulating hormone receptor 0.0237 0.1762 0.1762
Trichomonas vaginalis set domain proteins, putative 0.0729 0.5591 0.558
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.001 0.001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0214 0.1581 0.1581
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.0441 0.0441
Brugia malayi hypothetical protein 0.0053 0.033 0.033
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0209 0.036
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.1295 1 1
Loa Loa (eye worm) protein-S isoprenylcysteine O-methyltransferase 0.1295 1 1
Leishmania major hypothetical protein, conserved 0.0038 0.0211 0.0143
Schistosoma mansoni smad1 5 8 and 0.0018 0.0051 0.0051
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0068 0.0441 0.0441
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0211 0.0187
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0209 0.0141
Plasmodium vivax SET domain protein, putative 0.0093 0.0639 0.0587
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0209 0.0209
Schistosoma mansoni hypothetical protein 0.0068 0.0441 0.0441
Schistosoma mansoni smad 0.0018 0.0051 0.0051
Schistosoma mansoni hypothetical protein 0.0169 0.1227 0.1227
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0051 0.0051
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.1762 0.1762
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0211 0.0382
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0211 0.0187
Onchocerca volvulus 0.0038 0.0211 0.0196
Schistosoma mansoni hypothetical protein 0.0068 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0053 0.033 0.033

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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