Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0612 | 0.0612 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0294 | 0.0461 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0101 | 0.4516 | 0.4925 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0903 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.2111 | 0.4565 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0019 | 0.0622 | 0.0592 |
Toxoplasma gondii | ATPase, AAA family protein | 0.0012 | 0.0294 | 0.3837 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.0012 | 0.0294 | 0.3837 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0548 | 0.0509 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.0012 | 0.0294 | 0.3837 |
Echinococcus multilocularis | geminin | 0.0199 | 0.9076 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0622 | 0.1201 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0294 | 0.0461 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0548 | 0.0509 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.1471 | 0.1537 |
Schistosoma mansoni | troponin t invertebrate | 0.0142 | 0.6433 | 0.7059 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0012 | 0.0294 | 0.0461 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.0903 | 0.1836 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.001 | 0.02 | 0.0122 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0548 | 0.0548 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0622 | 0.0592 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0007 | 0.009 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0612 | 0.0612 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.009 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.009 | 0.009 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.0903 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.5138 | 0.5138 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0012 | 0.0294 | 0.3837 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.009 | 0.009 |
Treponema pallidum | DNA ligase (lig) | 0.0012 | 0.0294 | 0.5 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0622 | 0.0592 |
Echinococcus granulosus | Smad4 | 0.001 | 0.02 | 0.0122 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.1471 | 0.1471 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.0903 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.2266 | 0.2266 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0903 | 0.0903 |
Brugia malayi | MH2 domain containing protein | 0.001 | 0.02 | 0.02 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.001 | 0.02 | 0.0122 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.0012 | 0.0294 | 0.0461 |
Onchocerca volvulus | 0.0177 | 0.8067 | 1 | |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0101 | 0.4516 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0294 | 0.0294 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0007 | 0.009 | 0.0546 |
Loa Loa (eye worm) | Smad1 | 0.001 | 0.02 | 0.02 |
Brugia malayi | Troponin family protein | 0.0115 | 0.5138 | 0.5138 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0101 | 0.4516 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0019 | 0.0622 | 0.1201 |
Brugia malayi | MH1 domain containing protein | 0.001 | 0.02 | 0.02 |
Brugia malayi | Smad1 | 0.001 | 0.02 | 0.02 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0622 | 0.0592 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.009 | 0.0546 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0903 | 1 |
Brugia malayi | hypothetical protein | 0.0177 | 0.8067 | 0.8067 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.0903 | 1 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.0012 | 0.0294 | 0.0461 |
Brugia malayi | isocitrate dehydrogenase | 0.0019 | 0.0622 | 0.0622 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.001 | 0.02 | 0.02 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0565 | 0.6071 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.0012 | 0.0294 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.009 | 0.009 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0612 | 0.6617 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0012 | 0.0294 | 0.0461 |
Onchocerca volvulus | Troponin T, skeletal muscle homolog | 0.0142 | 0.6433 | 0.7952 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.8067 | 0.8067 |
Onchocerca volvulus | Troponin I homolog | 0.0115 | 0.5138 | 0.6328 |
Brugia malayi | MH2 domain containing protein | 0.001 | 0.02 | 0.02 |
Echinococcus granulosus | smad | 0.001 | 0.02 | 0.0122 |
Echinococcus multilocularis | Smad4 | 0.001 | 0.02 | 0.0122 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0007 | 0.009 | 0.009 |
Echinococcus granulosus | troponin i | 0.0115 | 0.5138 | 0.5617 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0019 | 0.0622 | 0.0622 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0007 | 0.009 | 0.0546 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.0903 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.001 | 0.02 | 0.0122 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0101 | 0.4516 | 0.4516 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0101 | 0.4516 | 0.4925 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4516 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.001 | 0.02 | 0.0122 |
Trypanosoma brucei | polo-like protein kinase | 0.0101 | 0.4516 | 1 |
Wolbachia endosymbiont of Brugia malayi | NAD-dependent DNA ligase, Lig | 0.0012 | 0.0294 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0101 | 0.4516 | 0.4925 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0101 | 0.4516 | 1 |
Echinococcus granulosus | nibrin | 0.0012 | 0.0294 | 0.0227 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.0012 | 0.0294 | 0.251 |
Brugia malayi | topoisomerase | 0.0012 | 0.0294 | 0.0294 |
Echinococcus multilocularis | smad | 0.001 | 0.02 | 0.0122 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0294 | 0.0461 |
Echinococcus multilocularis | troponin i | 0.0115 | 0.5138 | 0.5617 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0903 | 0.0903 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0548 | 0.0509 |
Onchocerca volvulus | Troponin T, skeletal muscle homolog | 0.0068 | 0.2947 | 0.3581 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0012 | 0.0294 | 0.0461 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0548 | 0.0509 |
Echinococcus multilocularis | oncosphere protein tso22e oncosphere protein tso22d oncosphere protein tso22c oncosphere protein tso22b oncosphere protein tso22 | 0.0142 | 0.6433 | 0.7059 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0012 | 0.0294 | 0.0461 |
Brugia malayi | Isocitrate dehydrogenase | 0.0019 | 0.0622 | 0.0622 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.001 | 0.02 | 0.0122 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0019 | 0.0622 | 0.0592 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.0903 | 0.1836 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0007 | 0.009 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0612 | 0.0612 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.009 | 0.009 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0903 | 1 |
Echinococcus granulosus | oncosphere protein Tso22e | 0.0142 | 0.6433 | 0.7059 |
Schistosoma mansoni | hypothetical protein | 0.0115 | 0.5138 | 0.5617 |
Loa Loa (eye worm) | oxidoreductase | 0.0007 | 0.009 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0548 | 0.0548 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0294 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0612 | 0.0612 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.0903 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 1 | 1 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.009 | 0.0546 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0101 | 0.4516 | 0.5548 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.2111 | 0.4565 |
Brugia malayi | hypothetical protein | 0.0068 | 0.2947 | 0.2947 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.009 | 0.009 |
Loa Loa (eye worm) | troponin T | 0.0068 | 0.2947 | 0.2947 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0565 | 0.6071 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.014 | 0.6321 | 0.6321 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0548 | 0.0509 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0903 | 0.1836 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0294 | 0.0294 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0903 | 0.1836 |
Schistosoma mansoni | troponin I | 0.0115 | 0.5138 | 0.5617 |
Schistosoma mansoni | hypothetical protein | 0.0199 | 0.9076 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1471 | 0.1471 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0903 | 0.0903 |
Brugia malayi | Troponin T | 0.0068 | 0.2947 | 0.2947 |
Schistosoma mansoni | Smad4 | 0.001 | 0.02 | 0.0122 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0294 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0294 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2947 | 0.2947 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0548 | 0.0509 |
Loa Loa (eye worm) | troponin | 0.0068 | 0.2947 | 0.2947 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0019 | 0.0622 | 1 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0012 | 0.0294 | 0.0461 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.0903 | 1 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0294 | 0.0294 |
Schistosoma mansoni | troponin I | 0.0115 | 0.5138 | 0.5617 |
Schistosoma mansoni | smad | 0.001 | 0.02 | 0.0122 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0012 | 0.0294 | 0.0461 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0903 | 0.1836 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0565 | 0.6071 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0622 | 0.0592 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.001 | 0.02 | 0.02 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4516 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0019 | 0.0622 | 0.0592 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0903 | 0.0903 |
Loa Loa (eye worm) | troponin I | 0.0115 | 0.5138 | 0.5138 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0007 | 0.009 | 0.009 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.009 | 0.0546 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0612 | 0.9817 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.014 | 0.6321 | 0.6321 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.0012 | 0.0294 | 0.0294 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0007 | 0.009 | 0.0546 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.001 | 0.02 | 0.0122 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4516 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0294 | 0.0461 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0548 | 0.0548 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0019 | 0.0622 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0612 | 1 |
Giardia lamblia | Kinase, PLK | 0.0101 | 0.4516 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.009 | 0.009 |
Schistosoma mansoni | topbp1 | 0.0012 | 0.0294 | 0.0227 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0019 | 0.0622 | 0.673 |
Echinococcus granulosus | replication factor c subunit 1 | 0.0012 | 0.0294 | 0.0227 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0019 | 0.0622 | 0.1201 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0101 | 0.4516 | 0.4516 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0622 | 0.1201 |
Brugia malayi | Troponin I | 0.0115 | 0.5138 | 0.5138 |
Brugia malayi | Troponin T | 0.0068 | 0.2947 | 0.2947 |
Schistosoma mansoni | DNA ligase IV | 0.0012 | 0.0294 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0294 | 0.0294 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0182 | 0.8281 | 0.9115 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.001 | 0.02 | 0.0122 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.0012 | 0.0294 | 0.0227 |
Echinococcus multilocularis | nibrin | 0.0012 | 0.0294 | 0.0227 |
Brugia malayi | MH2 domain containing protein | 0.014 | 0.6321 | 0.6321 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.0012 | 0.0294 | 0.251 |
Schistosoma mansoni | troponin I | 0.0115 | 0.5138 | 0.5617 |
Onchocerca volvulus | 0.0012 | 0.0294 | 0.0256 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4516 | 1 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.0012 | 0.0294 | 0.0461 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0612 | 0.6421 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0612 | 0.9817 |
Brugia malayi | DKFZp564C0469 protein | 0.0012 | 0.0294 | 0.0294 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.0903 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.0903 | 0.1836 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0294 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0294 | 0.0294 |
Echinococcus granulosus | geminin | 0.0199 | 0.9076 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0565 | 0.6071 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0294 | 0.0461 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0019 | 0.0622 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0101 | 0.4516 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.5138 | 0.5138 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0903 | 0.0903 |
Schistosoma mansoni | smad1 5 8 and | 0.001 | 0.02 | 0.0122 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.2266 | 0.2266 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4516 | 1 |
Onchocerca volvulus | 0.0025 | 0.0903 | 0.1019 | |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0548 | 0.0509 |
Schistosoma mansoni | topbp1 | 0.0012 | 0.0294 | 0.0227 |
Schistosoma mansoni | troponin I | 0.0115 | 0.5138 | 0.5617 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.009 | 0.009 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4516 | 1 |
Brugia malayi | MH1 domain containing protein | 0.001 | 0.02 | 0.02 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.0903 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0294 | 0.0294 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0007 | 0.009 | 0.0546 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0622 | 0.1201 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.0012 | 0.0294 | 0.0227 |
Entamoeba histolytica | hypothetical protein | 0.0012 | 0.0294 | 0.0461 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.009 | 0.0546 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0903 | 0.0903 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4516 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0019 | 0.0622 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0612 | 0.0612 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.009 | 0.0546 |
Schistosoma mansoni | kinase | 0.0052 | 0.2173 | 0.2318 |
Brugia malayi | Troponin T | 0.0068 | 0.2947 | 0.2947 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0548 | 0.0509 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0182 | 0.8281 | 0.9115 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.0903 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0548 | 0.0548 |
Schistosoma mansoni | hypothetical protein | 0.0199 | 0.9076 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.