Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.0662 | 0.2378 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0018 | 0.0102 | 0.0102 |
Trypanosoma brucei | L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative | 0.0071 | 0.0729 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0038 | 0.0344 | 0.1236 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0662 | 0.0662 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0662 | 0.0662 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0068 | 0.0691 | 0.9421 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.2783 | 0.2783 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0662 | 0.0662 |
Mycobacterium ulcerans | D-amino acid oxidase Aao | 0.0849 | 1 | 1 |
Mycobacterium ulcerans | glycerol-3-phosphate dehydrogenase GlpD2 | 0.0071 | 0.0729 | 0.0652 |
Brugia malayi | dihydrofolate reductase family protein | 0.0177 | 0.1992 | 0.7157 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0476 | 0.0476 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0102 | 0.0367 |
Plasmodium falciparum | FAD-dependent glycerol-3-phosphate dehydrogenase, putative | 0.0071 | 0.0729 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0102 | 0.0367 |
Trypanosoma brucei | cytochrome P450, putative | 0.0017 | 0.0082 | 0.0104 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0076 | 0.0272 |
Brugia malayi | dimethylglycine dehydrogenase, mitochondrial precursor, putative | 0.0071 | 0.0729 | 0.2618 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0102 | 0.0102 |
Entamoeba histolytica | anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative | 0.0071 | 0.0729 | 1 |
Trypanosoma cruzi | L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative | 0.0071 | 0.0729 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0038 | 0.0344 | 0.1236 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0102 | 0.0367 |
Plasmodium vivax | FAD-dependent glycerol-3-phosphate dehydrogenase, putative | 0.0071 | 0.0729 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0068 | 0.0694 | 0.9475 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0068 | 0.0691 | 0.9421 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0102 | 0.0367 |
Toxoplasma gondii | FAD-dependent glycerol-3-phosphate dehydrogenase | 0.0071 | 0.0729 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0102 | 0.0102 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0068 | 0.0694 | 0.9082 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0102 | 0.0367 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.0662 | 0.2378 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0076 | 0.0076 |
Giardia lamblia | Glycerol-3-phosphate dehydrogenase | 0.0071 | 0.0729 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0102 | 0.0367 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0102 | 0.0367 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0102 | 0.0367 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0102 | 0.0367 |
Mycobacterium ulcerans | D-amino acid oxidase Aao | 0.0071 | 0.0729 | 0.0652 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0102 | 0.0367 |
Brugia malayi | Cytochrome P450 family protein | 0.0017 | 0.0082 | 0.0296 |
Trypanosoma brucei | electron transfer flavoprotein-ubiquinone oxidoreductase, putative | 0.0071 | 0.0729 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0017 | 0.0082 | 0.0082 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0038 | 0.0344 | 0.1236 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0102 | 0.0102 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0102 | 0.0367 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0146 | 0.1629 | 0.5854 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0068 | 0.0694 | 0.2495 |
Schistosoma mansoni | NAD dehydrogenase | 0.0071 | 0.0729 | 0.0729 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0476 | 0.1712 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0102 | 0.0367 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0398 | 0.1431 |
Onchocerca volvulus | Putative fad oxidoreductase | 0.0071 | 0.0729 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0102 | 0.0102 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0102 | 0.0367 |
Mycobacterium ulcerans | glycerol-3-phosphate dehydrogenase | 0.0071 | 0.0729 | 0.0652 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.0386 | 0.0386 |
Schistosoma mansoni | glycerol-3-phosphate dehydrogenase | 0.0071 | 0.0729 | 0.0729 |
Onchocerca volvulus | Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial homolog | 0.0071 | 0.0729 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0076 | 0.0272 |
Trypanosoma cruzi | glycerol-3-phosphate dehydrogenase (FAD-dependent), putative | 0.0071 | 0.0729 | 1 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0039 | 0.0354 | 0.1271 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0398 | 0.4942 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0102 | 0.0367 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0068 | 0.0694 | 0.9475 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0068 | 0.0691 | 0.9421 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0068 | 0.0691 | 0.9421 |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0102 | 0.0367 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.0662 | 0.0662 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0102 | 0.0102 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0177 | 0.1992 | 1 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0071 | 0.0729 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0146 | 0.1629 | 0.1629 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0076 | 0.0272 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0068 | 0.0694 | 0.0694 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0076 | 0.0272 |
Echinococcus multilocularis | FAD dependent oxidoreductase domain containing protein | 0.0071 | 0.0729 | 0.2618 |
Trypanosoma cruzi | FAD dependent oxidoreductase, putative | 0.0071 | 0.0729 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0011 | 0.0018 | 0.0066 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0102 | 0.0102 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.0398 | 0.4942 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0102 | 0.0367 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.1962 | 0.1962 |
Onchocerca volvulus | Dimethylglycine dehydrogenase, mitochondrial homolog | 0.0071 | 0.0729 | 1 |
Trypanosoma brucei | glycerol-3-phosphate dehydrogenase (FAD-dependent), putative | 0.0071 | 0.0729 | 1 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0177 | 0.1992 | 0.7157 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.0398 | 0.4942 |
Schistosoma mansoni | d-amino acid oxidase | 0.0849 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0102 | 0.0367 |
Loa Loa (eye worm) | acetyltransferase | 0.0146 | 0.1629 | 0.1629 |
Brugia malayi | pyruvate dehydrogenase phosphatase regulatory subunit precursor | 0.0071 | 0.0729 | 0.2618 |
Leishmania major | cytochrome p450-like protein | 0.0017 | 0.0082 | 0.0104 |
Schistosoma mansoni | dihydrofolate reductase | 0.0177 | 0.1992 | 0.1992 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0102 | 0.0367 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0662 | 0.0662 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0076 | 0.0272 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0076 | 0.0076 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0177 | 0.1992 | 0.1992 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0011 | 0.0018 | 0.0018 |
Trypanosoma cruzi | glycerol-3-phosphate dehydrogenase (FAD-dependent), putative | 0.0071 | 0.0729 | 1 |
Schistosoma mansoni | ATP:guanidino kinase (Smc74) | 0.0071 | 0.0729 | 0.0729 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0017 | 0.0082 | 0.0082 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0177 | 0.1992 | 0.1362 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0018 | 0.0018 |
Echinococcus multilocularis | glycerol 3 phosphate dehydrogenase | 0.0071 | 0.0729 | 0.2618 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0102 | 0.0102 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0068 | 0.0691 | 0.9421 |
Trypanosoma cruzi | glycerol-3-phosphate dehydrogenase, putative | 0.0071 | 0.0729 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0102 | 0.0367 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0102 | 0.0367 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0102 | 0.0102 |
Trypanosoma cruzi | L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative | 0.0071 | 0.0729 | 1 |
Trypanosoma brucei | glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial | 0.0071 | 0.0729 | 1 |
Brugia malayi | hypothetical protein | 0.0243 | 0.2783 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0071 | 0.0729 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0102 | 0.0102 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0102 | 0.0367 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0102 | 0.0367 |
Brugia malayi | Cytochrome P450 family protein | 0.0017 | 0.0082 | 0.0296 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0076 | 0.0272 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0068 | 0.0694 | 0.2495 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0102 | 0.0367 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0017 | 0.0082 | 0.0104 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0017 | 0.0082 | 0.0082 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.0662 | 0.2378 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0076 | 0.0272 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0102 | 0.0367 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0102 | 0.0367 |
Schistosoma mansoni | fad oxidoreductase | 0.0071 | 0.0729 | 0.0729 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0011 | 0.0018 | 0.0066 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0102 | 0.0102 |
Leishmania major | hypothetical protein, conserved | 0.0071 | 0.0729 | 1 |
Brugia malayi | RE18450p | 0.0071 | 0.0729 | 0.2618 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0102 | 0.0102 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0102 | 0.0367 |
Echinococcus granulosus | geminin | 0.0174 | 0.1962 | 0.7049 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0102 | 0.0102 |
Brugia malayi | cDNA sequence BC016226 | 0.0071 | 0.0729 | 0.2618 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0476 | 0.0476 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0146 | 0.1629 | 0.5854 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0068 | 0.0691 | 0.9421 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0102 | 0.0102 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0076 | 0.0272 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.0356 | 0.4287 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0102 | 0.0367 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0068 | 0.0694 | 0.9475 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0102 | 0.0367 |
Echinococcus multilocularis | geminin | 0.0174 | 0.1962 | 0.7049 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0243 | 0.2783 | 1 |
Echinococcus granulosus | dihydrofolate reductase | 0.0177 | 0.1992 | 0.7157 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0102 | 0.0102 |
Schistosoma mansoni | fad oxidoreductase | 0.0071 | 0.0729 | 0.0729 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.0662 | 0.2378 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0662 | 0.0662 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0729 | 0.0729 |
Loa Loa (eye worm) | glycerol-3-phosphate dehydrogenase | 0.0071 | 0.0729 | 0.0729 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0177 | 0.1992 | 0.211 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0011 | 0.0018 | 0.0018 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0011 | 0.0018 | 0.0066 |
Echinococcus granulosus | voltage gated potassium channel | 0.0011 | 0.0018 | 0.0066 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0102 | 0.0102 |
Mycobacterium tuberculosis | Possible thiamine biosynthesis oxidoreductase ThiO | 0.0071 | 0.0729 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0102 | 0.0102 |
Mycobacterium tuberculosis | Probable D-amino acid oxidase Aao | 0.0778 | 0.9157 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.1962 | 0.1962 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0102 | 0.0102 |
Trypanosoma brucei | FAD dependent oxidoreductase, putative | 0.0071 | 0.0729 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.0662 | 0.0662 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0011 | 0.0018 | 0.0066 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0102 | 0.0367 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0102 | 0.0102 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0102 | 0.0367 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0102 | 0.0367 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0283 | 0.0283 |
Brugia malayi | follicle stimulating hormone receptor | 0.0238 | 0.2723 | 0.9786 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0102 | 0.0367 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0039 | 0.0354 | 0.1271 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0142 | 0.158 | 0.5678 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0102 | 0.0102 |
Mycobacterium leprae | PROBABLE D-AMINO ACID OXIDASE AAO | 0.0849 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0102 | 0.0367 |
Echinococcus granulosus | glycerol 3 phosphate dehydrogenase | 0.0071 | 0.0729 | 0.2618 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.0386 | 0.0386 |
Leishmania major | hypothetical protein, conserved | 0.0071 | 0.0729 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0068 | 0.0694 | 0.0694 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0177 | 0.1992 | 0.1925 |
Onchocerca volvulus | 0.005 | 0.0476 | 0.5975 | |
Brugia malayi | Dihydrofolate reductase | 0.0177 | 0.1992 | 0.7157 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0729 | 0.0729 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0102 | 0.0367 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0243 | 0.2783 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0102 | 0.0102 |
Leishmania major | glycerol-3-phosphate dehydrogenase-like protein | 0.0071 | 0.0729 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0398 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0102 | 0.0367 |
Echinococcus granulosus | FAD dependent oxidoreductase domain containing protein | 0.0071 | 0.0729 | 0.2618 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.0662 | 0.0662 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0068 | 0.0694 | 0.9475 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0068 | 0.0694 | 0.2495 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0102 | 0.0102 |
Brugia malayi | RNA binding protein | 0.0065 | 0.0662 | 0.2378 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0729 | 0.0729 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0398 | 1 |
Mycobacterium ulcerans | thiamine biosynthesis oxidoreductase ThiO | 0.0071 | 0.0729 | 0.0652 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0018 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0238 | 0.2723 | 0.2723 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0102 | 0.0367 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0038 | 0.0344 | 0.0344 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0102 | 0.0367 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 20 | 0.0071 | 0.0729 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0102 | 0.0367 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0102 | 0.0102 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0017 | 0.0082 | 0.0104 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.