Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | fucosidase alpha L 1 tissue | 0.0423 | 0.2637 | 0.4822 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.0479 | 0.0379 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0423 | 0.2637 | 0.5 |
Schistosoma mansoni | beta-galactosidase | 0.0522 | 0.3474 | 0.6694 |
Trichomonas vaginalis | glycoside hydrolases, putative | 0.0131 | 0.0155 | 0.0194 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.0256 | 0.1218 | 0.1126 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.0578 | 0.072 |
Loa Loa (eye worm) | glycosyl hydrolase family 2 | 0.0417 | 0.2585 | 0.2507 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0696 | 0.4953 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0696 | 0.4953 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0159 | 0.04 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0522 | 0.3474 | 0.3406 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0757 | 0.5469 | 0.6807 |
Brugia malayi | manba-prov protein | 0.0245 | 0.1131 | 0.4346 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.0578 | 0.072 |
Trichomonas vaginalis | glycoside hydrolase, putative | 0.1059 | 0.8034 | 1 |
Trichomonas vaginalis | beta-glucosidase, putative | 0.0131 | 0.0155 | 0.0194 |
Brugia malayi | Cytochrome P450 family protein | 0.0124 | 0.0104 | 0.0354 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.0578 | 0.072 |
Trichomonas vaginalis | beta-hexosaminidase B, putative | 0.017 | 0.049 | 0.061 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0275 | 0.138 | 0.1718 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0275 | 0.138 | 0.129 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0275 | 0.138 | 0.5316 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.0578 | 0.072 |
Trichomonas vaginalis | beta-galactosidase, putative | 0.0757 | 0.5469 | 0.6807 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0275 | 0.138 | 0.1718 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.019 | 0.0661 | 0.0822 |
Toxoplasma gondii | melibiase subfamily protein | 0.0169 | 0.0479 | 0.5 |
Echinococcus granulosus | beta hexosaminidase subunit alpha | 0.017 | 0.049 | 0.0025 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0696 | 0.4953 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.0578 | 0.072 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.017 | 0.049 | 0.061 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.0578 | 0.072 |
Brugia malayi | Beta-glucuronidase precursor | 0.0396 | 0.2412 | 0.9325 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.017 | 0.049 | 0.061 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0275 | 0.138 | 0.1718 |
Echinococcus multilocularis | beta galactosidase | 0.0522 | 0.3474 | 0.6694 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.0256 | 0.1218 | 0.4685 |
Echinococcus granulosus | beta galactosidase | 0.0522 | 0.3474 | 0.6694 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.018 | 0.0578 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0329 | 0.0228 |
Loa Loa (eye worm) | beta-glucuronidase | 0.0396 | 0.2412 | 0.2332 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.0578 | 0.072 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0275 | 0.138 | 0.1718 |
Echinococcus multilocularis | beta hexosaminidase subunit alpha | 0.017 | 0.049 | 0.0025 |
Schistosoma mansoni | alpha-l-fucosidase | 0.0256 | 0.1218 | 0.1651 |
Entamoeba histolytica | beta-galactosidase, putative | 0.0511 | 0.3387 | 0.5 |
Trichomonas vaginalis | beta-mannosidase, putative | 0.0245 | 0.1131 | 0.1407 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0159 | 0.04 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.019 | 0.0661 | 0.0822 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.017 | 0.049 | 0.061 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0275 | 0.138 | 0.1718 |
Schistosoma mansoni | hypothetical protein | 0.0568 | 0.3869 | 0.7577 |
Brugia malayi | Melibiase family protein | 0.0169 | 0.0479 | 0.1813 |
Brugia malayi | Glycosyl hydrolases family 2, sugar binding domain containing protein | 0.0417 | 0.2585 | 1 |
Schistosoma mansoni | beta-mannosidase | 0.0245 | 0.1131 | 0.1456 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0169 | 0.0479 | 0.0596 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0423 | 0.2637 | 0.4822 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0275 | 0.138 | 0.1718 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.