Detailed information for compound 910913

Basic information

Technical information
  • TDR Targets ID: 910913
  • Name: butyl 4-methyl-2-oxo-6-[2-(phenylmethoxy)phen yl]-3,6-dihydro-1H-pyrimidine-5-carboxylate
  • MW: 394.464 | Formula: C23H26N2O4
  • H donors: 2 H acceptors: 2 LogP: 3.73 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCOC(=O)C1=C(C)NC(=O)NC1c1ccccc1OCc1ccccc1
  • InChi: 1S/C23H26N2O4/c1-3-4-14-28-22(26)20-16(2)24-23(27)25-21(20)18-12-8-9-13-19(18)29-15-17-10-6-5-7-11-17/h5-13,21H,3-4,14-15H2,1-2H3,(H2,24,25,27)
  • InChiKey: HHZBEFMPOCTCBR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-methyl-2-oxo-6-[2-(phenylmethoxy)phenyl]-3,6-dihydro-1H-pyrimidine-5-carboxylic acid butyl ester
  • 4-[2-(benzyloxy)phenyl]-2-keto-6-methyl-3,4-dihydro-1H-pyrimidine-5-carboxylic acid butyl ester
  • AG-690/09695061
  • BAS 00381617

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0042
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.023 0.0841
Loa Loa (eye worm) carboxylesterase 0.0011 0.0012 0.0043
Brugia malayi hypothetical protein 0.0022 0.0106 0.0389
Schistosoma mansoni hypothetical protein 0.0031 0.0193 0.0707
Brugia malayi Carboxylesterase family protein 0.0066 0.0511 0.1871
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0282 0.1034
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0042
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0106 0.0389
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0067 0.0521 0.0521
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0556 1
Onchocerca volvulus 0.0029 0.017 0.0623
Loa Loa (eye worm) hypothetical protein 0.0146 0.1236 0.4529
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0106 0.0106
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0556 0.2037
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0193 0.0707
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.01 0.1619
Brugia malayi CHE-14 protein 0.0042 0.0292 0.1071
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0293
Schistosoma mansoni BC026374 protein (S09 family) 0.0011 0.0012 0.0043
Loa Loa (eye worm) TAR-binding protein 0.0085 0.0679 0.2487
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0065 0.5
Trichomonas vaginalis spcc417.12 protein, putative 0.0011 0.0012 0.0001
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0106 0.0106
Schistosoma mansoni tar DNA-binding protein 0.0085 0.0679 0.2487
Onchocerca volvulus 0.0022 0.0106 0.0389
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0106 0.0106
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0106 0.0106
Echinococcus granulosus g protein coupled receptor 0.0022 0.0106 0.0106
Echinococcus multilocularis vesicular acetylcholine transporter 0.0311 0.2729 0.2729
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0556 0.2037
Echinococcus granulosus neuroligin 0.0011 0.0012 0.0012
Loa Loa (eye worm) carboxylesterase 0.0011 0.0012 0.0043
Schistosoma mansoni cpg binding protein 0.003 0.0185 0.0677
Loa Loa (eye worm) hypothetical protein 0.0123 0.1026 0.3759
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0106 0.0106
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.1182 0.1182
Brugia malayi TAR-binding protein 0.0085 0.0679 0.2487
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0106 0.0389
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0529 0.1937
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.01 0.0366
Brugia malayi chromobox protein homolog 3 0.0038 0.0257 0.0941
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0106 0.0389
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis sex peptide receptor 0.0022 0.0106 0.0106
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Onchocerca volvulus 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Onchocerca volvulus 0.0022 0.0106 0.0389
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0039 0.0136
Brugia malayi Heterochromatin protein 1 0.0068 0.0529 0.1937
Brugia malayi hypothetical protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.01 0.5
Schistosoma mansoni neuropeptide receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0106 0.0106
Echinococcus granulosus neuropeptide receptor 0.0022 0.0106 0.0106
Entamoeba histolytica hypothetical protein 0.0035 0.023 0.2764
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0026 0.0096
Brugia malayi SET domain containing protein 0.0013 0.0027 0.0099
Echinococcus multilocularis chromobox protein 1 0.0068 0.0529 0.0529
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0106 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0106 0.0389
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0106 0.0106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.01 0.1619
Onchocerca volvulus 0.0071 0.0556 0.2037
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0106 0.0106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0366 0.6517
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0043 0.0157
Echinococcus granulosus fmrfamide receptor 0.0022 0.0106 0.0106
Entamoeba histolytica hypothetical protein 0.0035 0.023 0.2764
Echinococcus multilocularis protein patched 0.0042 0.0292 0.0292
Onchocerca volvulus 0.0011 0.0012 0.0043
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.01 0.1619
Brugia malayi hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis protein dispatched 1 0.0048 0.0346 0.0346
Brugia malayi CXXC zinc finger family protein 0.0029 0.017 0.0623
Brugia malayi hypothetical protein 0.0035 0.023 0.0841
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0106 0.0389
Schistosoma mansoni hypothetical protein 0.0041 0.0279 0.1021
Schistosoma mansoni tar DNA-binding protein 0.0085 0.0679 0.2487
Brugia malayi neuropeptide F receptor 0.0022 0.0106 0.0389
Echinococcus granulosus orexin receptor type 2 0.0022 0.0106 0.0106
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0065 0.097
Schistosoma mansoni tar DNA-binding protein 0.0085 0.0679 0.2487
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.003 0.0181 0.0663
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Onchocerca volvulus 0.0022 0.0106 0.0389
Brugia malayi hypothetical protein 0.0022 0.0106 0.0389
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0106 0.0389
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0292 0.0292
Echinococcus multilocularis muscleblind protein 1 0.0146 0.1236 0.1236
Onchocerca volvulus 0.0022 0.0106 0.0389
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0181 0.0181
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.01 0.1619
Schistosoma mansoni hypothetical protein 0.0022 0.0106 0.0389
Schistosoma mansoni neuroligin 3 (S09 family) 0.0011 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0556 0.69
Schistosoma mansoni hypothetical protein 0.0022 0.0106 0.0389
Echinococcus granulosus carboxylesterase 5A 0.0066 0.0511 0.0511
Brugia malayi hypothetical protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Onchocerca volvulus 0.0123 0.1026 0.3759
Schistosoma mansoni biogenic amine receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis GPCR, family 2 0.0031 0.0193 0.0193
Echinococcus granulosus chromobox protein 2 0.0011 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0022 0.0106 0.0389
Brugia malayi vesicular acetylcholine transporter unc-17 0.0311 0.2729 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.017 0.0623
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.01 0.1619
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0106 0.0106
Echinococcus multilocularis chromobox protein 2 0.0011 0.0012 0.0012
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0106 0.0106
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.0106 0.0389
Brugia malayi hypothetical protein 0.0022 0.0106 0.0389
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0067 0.0521 0.1909
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.01 0.1619
Onchocerca volvulus 0.0022 0.0106 0.0389
Brugia malayi CHD4 protein 0.0013 0.0026 0.0096
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.01 0.1619
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0556 1
Echinococcus granulosus expressed conserved protein 0.0092 0.0746 0.0746
Brugia malayi G protein-coupled receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0106 0.0106
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0393 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0106 0.0389
Schistosoma mansoni myosin xvIII 0.0022 0.0106 0.0389
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0106 0.0389
Onchocerca volvulus 0.0011 0.0012 0.0043
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0106 0.0106
Brugia malayi putative neuropeptide receptor 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0257 0.1223
Brugia malayi RNA binding protein 0.0085 0.0679 0.2487
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0011 0.0012 0.0001
Onchocerca volvulus 0.0022 0.0106 0.0389
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0106 0.0389
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0106 0.0389
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0106 0.0389
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0181 0.0181
Onchocerca volvulus 0.0022 0.0106 0.0389
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.01 0.2206
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0106 0.0106
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0556 1
Echinococcus granulosus serotonin receptor 0.0022 0.0106 0.0106
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0106 0.0106
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0257 0.0941
Schistosoma mansoni amine GPCR 0.0022 0.0106 0.0389
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.01 0.5
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0106 0.0106
Echinococcus multilocularis expressed protein 0.0017 0.0065 0.0065
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.01 0.5
Brugia malayi AKH receptor 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0293
Loa Loa (eye worm) hypothetical protein 0.0053 0.0393 0.1439
Brugia malayi hypothetical protein 0.0022 0.0106 0.0389
Onchocerca volvulus 0.0011 0.0012 0.0043
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.01 0.1619
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0106 0.0389
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.01 0.1619
Onchocerca volvulus 0.0022 0.0106 0.0389
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0193 0.0193
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0012 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0293
Loa Loa (eye worm) hypothetical protein 0.0042 0.0292 0.1071
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0106 0.0389
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0053 0.0393 0.1439
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.01 0.0366
Onchocerca volvulus 0.0022 0.0106 0.0389
Onchocerca volvulus 0.003 0.0182 0.0667
Loa Loa (eye worm) hypothetical protein 0.0066 0.0511 0.1871
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0065 0.5
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.01 0.1619
Loa Loa (eye worm) RNA binding protein 0.0085 0.0679 0.2487
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0106 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0052 0.0378 0.1386
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0074 0.1135
Onchocerca volvulus 0.0022 0.0106 0.0389
Brugia malayi Carboxylesterase family protein 0.0011 0.0012 0.0043
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0106 0.0106
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0311 0.2729 1
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0106 0.0106
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0067 0.0521 0.0521
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0106 0.0106
Echinococcus granulosus g protein coupled receptor 0.0022 0.0106 0.0106
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0085 0.0679 0.2487
Onchocerca volvulus 0.0022 0.0106 0.0389
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0106 0.0389
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.01 0.2318
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0042
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.01 0.044
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.023 0.023
Schistosoma mansoni chromobox protein 0.0068 0.0529 0.1937
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0067 0.0521 0.1909
Brugia malayi Muscleblind-like protein 0.0146 0.1236 0.4529
Trichomonas vaginalis ferritin, putative 0.0017 0.0065 0.0264
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0393 0.5
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0106 0.0389
Loa Loa (eye worm) acetylcholinesterase 1 0.0066 0.0511 0.1871
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.01 0.1619
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0043 0.0157
Brugia malayi hypothetical protein 0.0022 0.0106 0.0389
Brugia malayi hypothetical protein 0.0022 0.0106 0.0389
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0012 0.0042
Onchocerca volvulus 0.0022 0.0106 0.0389
Schistosoma mansoni hypothetical protein 0.0174 0.1489 0.5454
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.01 0.1619
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0556 1
Echinococcus multilocularis cpg binding protein 0.003 0.0185 0.0185
Echinococcus granulosus acetylcholinesterase 0.0066 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0038 0.0257 0.0941
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0011 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0257 0.1223
Echinococcus granulosus ferritin 0.0017 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0011 0.0012 0.0012
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0012 0.0042
Echinococcus granulosus Chromo domain 0.0011 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0556 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0106 0.0106
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0556 0.69
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0106 0.0106
Echinococcus granulosus neuropeptide receptor A26 0.0022 0.0106 0.0106
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0106 0.0106
Onchocerca volvulus 0.0011 0.0012 0.0042
Echinococcus multilocularis expressed conserved protein 0.0092 0.0746 0.0746
Brugia malayi AMP-binding enzyme family protein 0.0021 0.01 0.0366
Brugia malayi sulfakinin receptor protein 0.0022 0.0106 0.0389
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0067 0.0521 0.0521
Echinococcus multilocularis somatostatin receptor 0.0022 0.0106 0.0106
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0311 0.2729 1
Echinococcus multilocularis carboxylesterase 5A 0.0066 0.0511 0.0511
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.01 0.1619
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Brugia malayi RNA recognition motif domain containing protein 0.0085 0.0679 0.2487
Brugia malayi AMP-binding enzyme family protein 0.0021 0.01 0.0366
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0106 0.0389
Onchocerca volvulus 0.0011 0.0012 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Echinococcus multilocularis para nitrobenzyl esterase 0.0011 0.0012 0.0012
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0106 0.0389
Schistosoma mansoni hypothetical protein 0.0041 0.0279 0.1021
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0556 1
Brugia malayi hypothetical protein 0.0123 0.1026 0.3759
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.01 0.0366
Onchocerca volvulus 0.0022 0.0106 0.0389
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0026 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Schistosoma mansoni hypothetical protein 0.0011 0.0012 0.0042
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.1182 0.1182
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.01 0.2206
Onchocerca volvulus 0.0022 0.0106 0.0389
Echinococcus granulosus expressed protein 0.0017 0.0065 0.0065
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.08 0.08
Schistosoma mansoni biogenic amine receptor 0.0022 0.0106 0.0389
Brugia malayi Carboxylesterase family protein 0.0011 0.0012 0.0043
Schistosoma mansoni chromobox protein 0.0011 0.0012 0.0042
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.01 0.112
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Schistosoma mansoni gliotactin 0.0011 0.0012 0.0043
Echinococcus multilocularis chromobox protein 1 0.0068 0.0529 0.0529
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis geminin 0.0174 0.1489 0.1489
Echinococcus granulosus hypothetical protein 0.0022 0.0106 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0053 0.0393 0.1439
Schistosoma mansoni apoferritin-2 0.0017 0.0065 0.0236
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0065 0.097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0283 0.1038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Schistosoma mansoni ferritin 0.0017 0.0065 0.0236
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0393 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0193 0.0193
Schistosoma mansoni chromobox protein 0.0068 0.0529 0.1937
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0106 0.0106
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0022 0.0106 0.0389
Brugia malayi Protein cec-1. 0.0011 0.0012 0.0042
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0043
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0012 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0106 0.0389
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0106 0.0106
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0293
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.0106 0.0389
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0106 0.0389
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0181 0.0181
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0106 0.0106
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.01 0.01
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.01 0.01
Echinococcus granulosus neuropeptide s receptor 0.0022 0.0106 0.0106
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0556 1
Entamoeba histolytica hypothetical protein 0.0035 0.023 0.2764
Brugia malayi Serotonin receptor 0.0022 0.0106 0.0389
Schistosoma mansoni hypothetical protein 0.0067 0.0521 0.1908
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0803 0.2944
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0106 0.0389
Brugia malayi Carboxylesterase family protein 0.0066 0.0511 0.1871
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0529 0.2577
Schistosoma mansoni neuropeptide receptor 0.0022 0.0106 0.0389
Echinococcus granulosus BC026374 protein S09 family 0.0011 0.0012 0.0012
Schistosoma mansoni acetylcholinesterase 0.0011 0.0012 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.01 0.1619
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0393 0.7001
Echinococcus multilocularis tar DNA binding protein 0.0085 0.0679 0.0679
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) carboxylesterase 0.0066 0.0511 0.1871
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0471 0.1725
Loa Loa (eye worm) hypothetical protein 0.0031 0.0193 0.0707
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0043
Mycobacterium ulcerans hypothetical protein 0.0071 0.0556 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0292 0.1071
Schistosoma mansoni adenoreceptor 0.0022 0.0106 0.0389
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0106 0.0389
Echinococcus multilocularis neuropeptide receptor A26 0.0022 0.0106 0.0106
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.007 0.0293
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0106 0.0106
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0556 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.007 0.0293
Schistosoma mansoni ferritin 0.0017 0.0065 0.0236
Schistosoma mansoni neuropeptide receptor 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0042
Schistosoma mansoni amine GPCR 0.0022 0.0106 0.0389
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0106 0.0389
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0556 0.2037
Schistosoma mansoni chromobox protein 0.0011 0.0012 0.0042
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0106 0.0106
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0106 0.0106
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0412 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0067 0.0521 0.0521
Loa Loa (eye worm) hypothetical protein 0.003 0.0182 0.0667
Loa Loa (eye worm) hypothetical protein 0.0053 0.0393 0.1439
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0012 0.0012
Loa Loa (eye worm) helicase 0.0011 0.0012 0.0042
Schistosoma mansoni hypothetical protein 0.0031 0.0193 0.0707
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0181 0.0663
Plasmodium vivax SET domain protein, putative 0.003 0.0181 0.4444
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis neuroligin 0.0011 0.0012 0.0012
Onchocerca volvulus 0.0021 0.01 0.0366
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0106 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0066 0.0511 0.1871
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0106 0.0389
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0012 0.0043
Echinococcus granulosus allatostatin A receptor 0.0022 0.0106 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.01 0.1619
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.01 0.1619
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0556 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0067 0.0521 0.1908
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.0106 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0106 0.0389
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0292 0.1399
Brugia malayi ORL1-like opioid receptor 0.0022 0.0106 0.0389
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0106 0.0389
Schistosoma mansoni ferritin 0.0017 0.0065 0.0236
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0106 0.0389
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0393 0.7001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0106 0.0389
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.01 0.2318
Onchocerca volvulus 0.0021 0.01 0.0366
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0193 0.0193
Brugia malayi larval opioid receptor 0.0022 0.0106 0.0389
Brugia malayi AMP-binding enzyme family protein 0.0021 0.01 0.0366
Loa Loa (eye worm) oxidoreductase 0.0021 0.01 0.0366
Echinococcus granulosus vesicular acetylcholine transporter 0.0311 0.2729 0.2729
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0106 0.0106
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0106 0.0389
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis ferritin 0.0017 0.0065 0.0065
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0106 0.0106
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0106 0.0106
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0066 0.0511 0.1871
Schistosoma mansoni tar DNA-binding protein 0.0085 0.0679 0.2487
Schistosoma mansoni biogenic amine receptor 0.0022 0.0106 0.0389
Toxoplasma gondii propionate-CoA ligase 0.0021 0.01 0.2206
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0043
Echinococcus granulosus chromobox protein 1 0.0068 0.0529 0.0529
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0181 0.423
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0556 1
Echinococcus granulosus sex peptide receptor 0.0022 0.0106 0.0106
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0106 0.0106
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0556 1
Schistosoma mansoni hypothetical protein 0.0031 0.0193 0.0707
Schistosoma mansoni opsin-like receptor 0.0022 0.0106 0.0389
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.01 0.0366
Schistosoma mansoni amine GPCR 0.0022 0.0106 0.0389
Schistosoma mansoni hypothetical protein 0.0041 0.0279 0.1021
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.01 0.5
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0106 0.0106
Echinococcus granulosus cpg binding protein 0.003 0.0185 0.0185
Schistosoma mansoni cpg binding protein 0.0029 0.017 0.0623
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0067 0.0521 0.1909
Schistosoma mansoni patched 1 0.0042 0.0292 0.1071
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.01 0.1619
Echinococcus granulosus muscleblind protein 0.0146 0.1236 0.1236
Echinococcus multilocularis muscleblind protein 0.0146 0.1236 0.1236
Brugia malayi follicle stimulating hormone receptor 0.0022 0.0106 0.0389
Schistosoma mansoni hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis Chromo domain 0.0011 0.0012 0.0012
Brugia malayi neuropeptide F receptor 0.0022 0.0106 0.0389
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.01 0.1619
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0556 1
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.01 0.5
Schistosoma mansoni ferritin light chain 0.0017 0.0065 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0106 0.0389
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0193 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0156 0.0719
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0067 0.0521 0.1909
Onchocerca volvulus 0.0021 0.01 0.0366
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.01 0.044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0366 0.6517
Schistosoma mansoni tar DNA-binding protein 0.0085 0.0679 0.2487
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0042
Schistosoma mansoni hypothetical protein 0.0174 0.1489 0.5454
Schistosoma mansoni opsin-like receptor 0.0022 0.0106 0.0389
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0193 0.0707
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.01 0.0366
Echinococcus multilocularis neuropeptide s receptor 0.0022 0.0106 0.0106
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0293
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0814 0.2983
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0012 0.0042
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.01 0.0719
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0803 0.2944
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0292 0.0292
Echinococcus granulosus tar DNA binding protein 0.0085 0.0679 0.0679
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Schistosoma mansoni neuropeptide receptor 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0021 0.01 0.0366
Brugia malayi Melatonin receptor type 1A 0.0022 0.0106 0.0389
Entamoeba histolytica hypothetical protein 0.0035 0.023 0.2764
Onchocerca volvulus 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0021 0.01 0.0366
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.01 0.1619
Loa Loa (eye worm) hypothetical protein 0.0053 0.0393 0.1439
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.1763 0.646
Brugia malayi RE15519p 0.0022 0.0106 0.0389
Brugia malayi Carboxylesterase family protein 0.0011 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus granulosus somatostatin receptor 0.0022 0.0106 0.0106
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.01 0.1619
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.01 0.1619
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0556 0.69
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0803 0.2944
Onchocerca volvulus 0.0011 0.0012 0.0043
Echinococcus granulosus chromobox protein 1 0.0068 0.0529 0.0529
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0106 0.0106
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0012 0.0042
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0106 0.0389
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.08 0.2933
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.01 0.1619
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0106 0.0106
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.01 0.5
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0067 0.0521 0.1909
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0106 0.0106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0366 0.6517
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis serotonin receptor 0.0022 0.0106 0.0106
Brugia malayi Serotonin receptor 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0012 0.0012
Schistosoma mansoni ferritin light chain 0.0017 0.0065 0.0236
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0511 0.0511
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0106 0.0106
Brugia malayi G-protein coupled receptor 0.0022 0.0106 0.0389
Echinococcus granulosus g protein coupled receptor 0.0022 0.0106 0.0106
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0521 0.1908
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0106 0.0106
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0181 0.0663
Onchocerca volvulus 0.0041 0.0282 0.1034
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0511 0.0511
Onchocerca volvulus 0.0021 0.01 0.0366
Onchocerca volvulus 0.0022 0.0106 0.0389
Echinococcus granulosus geminin 0.0174 0.1489 0.1489
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.01 0.0719
Schistosoma mansoni apoferritin-2 0.0017 0.0065 0.0236
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0106 0.0106
Brugia malayi hypothetical protein 0.0011 0.0012 0.0043
Brugia malayi hypothetical protein 0.0011 0.0012 0.0042
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0071 0.0556 0.2037
Schistosoma mansoni hypothetical protein 0.0031 0.0193 0.0707
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0043
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.08 1
Brugia malayi Dopamine receptor protein 2 0.0022 0.0106 0.0389
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0193 0.0707
Loa Loa (eye worm) hypothetical protein 0.0071 0.0556 0.2037
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0292 0.0292
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0042
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.01 0.1619
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0098 0.08 0.2933
Schistosoma mansoni hypothetical protein 0.0041 0.0279 0.1021
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0012 0.0042
Onchocerca volvulus 0.0233 0.2018 0.7395
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0283 0.1354
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0156 0.0719
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0106 0.0106
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0556 1
Trichomonas vaginalis set domain proteins, putative 0.0233 0.2018 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.01 0.1619
Brugia malayi GnHR receptor homolog 0.0022 0.0106 0.0389
Schistosoma mansoni opsin-like receptor 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0099 0.0803 0.2944
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.01 0.1619
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0106 0.0106
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0065 0.097
Schistosoma mansoni vesicular acetylcholine transporter 0.0311 0.2729 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.01 0.1619
Schistosoma mansoni amine GPCR 0.0022 0.0106 0.0389
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0165 0.0165
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.01 0.1619
Schistosoma mansoni amine GPCR 0.0022 0.0106 0.0389
Brugia malayi Pre-SET motif family protein 0.0205 0.1763 0.646
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0556 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.08 0.08
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0026 0.0026
Brugia malayi Dopamine receptor 0.0022 0.0106 0.0389
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0106 0.0389
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0106 0.0106
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.01 0.1619
Schistosoma mansoni hypothetical protein 0.0035 0.023 0.0841
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0106 0.0106
Brugia malayi AMP-binding enzyme family protein 0.0021 0.01 0.0366
Brugia malayi hypothetical protein 0.0022 0.0106 0.0389
Loa Loa (eye worm) histone methyltransferase 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0146 0.1236 0.4529
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.01 0.0719
Echinococcus granulosus acetylcholinesterase 0.0066 0.0511 0.0511
Brugia malayi Carboxylesterase family protein 0.0011 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus granulosus neuropeptide receptor 0.0022 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus multilocularis BC026374 protein (S09 family) 0.0011 0.0012 0.0012
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0012 0.0042
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0106 0.0389
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0106 0.0389
Onchocerca volvulus 0.0011 0.0012 0.0043
Schistosoma mansoni histamine h1 receptor 0.0022 0.0106 0.0389
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0071 0.0556 0.2037
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0181 0.0663
Schistosoma mansoni cpg binding protein 0.003 0.0185 0.0677
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0106 0.0389
Echinococcus multilocularis serotonin receptor 0.0022 0.0106 0.0106
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0283 0.1354
Brugia malayi Pre-SET motif family protein 0.003 0.0181 0.0663
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0529 0.2577
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0293
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1114 1 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0106 0.0106
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0106 0.0106
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0106 0.0106
Schistosoma mansoni ferritin 0.0017 0.0065 0.0236
Brugia malayi Dopamine receptor protein 1 0.0022 0.0106 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0106 0.0389
Echinococcus granulosus para nitrobenzyl esterase 0.0011 0.0012 0.0012
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0366 0.6517
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus granulosus GPCR family 2 0.0031 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0022 0.0106 0.0389
Echinococcus granulosus Chromobox protein 3 0.0011 0.0012 0.0012
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0106 0.0106
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0065 0.097
Brugia malayi G-protein coupled receptor 0.0022 0.0106 0.0389
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0106 0.0106

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.