Detailed information for compound 932069

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 474.395 | Formula: C26H26Cl2FNO2
  • H donors: 1 H acceptors: 1 LogP: 7.32 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)C[C@@H](c1ccccc1F)[C@@H](NC(=O)C(Oc1ccc(cc1)Cl)(C)C)C
  • InChi: 1S/C26H26Cl2FNO2/c1-17(30-25(31)26(2,3)32-21-14-12-20(28)13-15-21)23(22-6-4-5-7-24(22)29)16-18-8-10-19(27)11-9-18/h4-15,17,23H,16H2,1-3H3,(H,30,31)/t17-,23+/m0/s1
  • InChiKey: UAQZEOXBFRPEBY-GAJHUEQPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cannabinoid receptor 2 (macrophage) Starlite/ChEMBL References
Homo sapiens cannabinoid receptor 1 (brain) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus activin receptor type 0.0288 0.1828 0.1828
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0355 0.2287 0.2287
Giardia lamblia G2/mitotic-specific cyclin B 0.0132 0.0765 1
Schistosoma mansoni nAChR subunit 0.0513 0.3367 0.3832
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0513 0.3367 0.3367
Schistosoma mansoni neuropeptide receptor 0.0042 0.0146 0.0166
Plasmodium vivax importin-beta 2, putative 0.0033 0.0089 0.4222
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0094 0.0887
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0294 0.1872 0.1872
Echinococcus multilocularis G protein coupled receptor 139 0.0546 0.3587 0.3587
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0513 0.3367 0.3367
Brugia malayi hypothetical protein 0.0042 0.0146 0.0146
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0088 0.046 0.5859
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0042 0.0146 0.0146
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0032 0.0079 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0146 0.0166
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0053 0.2213
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0132 0.0765 1
Echinococcus multilocularis glycine receptor subunit beta 0.0513 0.3367 0.3367
Loa Loa (eye worm) TK protein kinase 0.0067 0.032 0.032
Onchocerca volvulus 0.0042 0.0146 0.0146
Brugia malayi Kringle domain containing protein 0.0051 0.0211 0.0211
Echinococcus granulosus neuropeptides capa receptor 0.0042 0.0146 0.0146
Schistosoma mansoni twik family of potassium channels-related 0.0032 0.0079 0.009
Leishmania major cyclin 0.0132 0.0765 1
Echinococcus granulosus G protein coupled receptor kinase 1 0.0082 0.0419 0.0419
Brugia malayi Trypsin family protein 0.0029 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0077 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Echinococcus granulosus tyrosine protein kinase Fyn 0.0074 0.0369 0.0369
Echinococcus granulosus integrin alpha ps 0.0033 0.0089 0.0089
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Echinococcus multilocularis g protein coupled receptor 0.0042 0.0146 0.0146
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0055 0.0238 0.0238
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0074 0.0369 0.0369
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0237 0.1479 0.1479
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0237 0.1479 0.1479
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0067 0.032 0.032
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0243 0.152 0.152
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Schistosoma mansoni cyclin B 0.0132 0.0765 0.087
Brugia malayi follicle stimulating hormone receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0042 0.0146 0.0146
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0042 0.0146 0.0146
Entamoeba histolytica protein kinase, putative 0.006 0.0269 0.1427
Brugia malayi G-protein coupled receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0132 0.0765 0.0765
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Onchocerca volvulus Cirhin homolog 0.0097 0.0523 0.0523
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Brugia malayi Transforming growth factor beta like domain containing protein 0.0064 0.0302 0.0302
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0042 0.0146 0.0166
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Echinococcus multilocularis beta adrenergic receptor kinase 0.0091 0.0483 0.0483
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0327 0.2091 0.2091
Schistosoma mansoni amine GPCR 0.0042 0.0146 0.0166
Brugia malayi AKH receptor 0.0042 0.0146 0.0146
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0065 0.0306 0.0306
Brugia malayi Tachykinin-like peptides receptor 99D 0.0042 0.0146 0.0146
Schistosoma mansoni protein kinase 0.0633 0.4183 0.476
Schistosoma mansoni hypothetical protein 0.0026 0.0042 0.0047
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0032 0.0079 0.0079
Loa Loa (eye worm) integrin alpha pat-2 0.0239 0.1493 0.1493
Schistosoma mansoni acetylcholine receptor-related 0.0237 0.1479 0.1683
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0032 0.0079 0.0675
Onchocerca volvulus 0.0032 0.0079 0.0079
Brugia malayi G-protein coupled receptor 0.0042 0.0146 0.0146
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0074 0.0369 0.0369
Echinococcus multilocularis g-protein coupled receptor 0.0042 0.0146 0.0146
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0042 0.0146 0.0146
Echinococcus granulosus geminin 0.0188 0.1145 0.1145
Onchocerca volvulus 0.0042 0.0146 0.0146
Echinococcus multilocularis tyrosine protein kinase Srms 0.0067 0.032 0.032
Trichomonas vaginalis cyclins, putative 0.0132 0.0765 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0042 0.0146 0.0166
Leishmania major importin beta-1 subunit, putative 0.0027 0.0046 0.0316
Brugia malayi Dopamine receptor 0.0042 0.0146 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0032 0.0079 0.0079
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0513 0.3367 0.3367
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0051 0.0211 0.0211
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0079 0.0675
Echinococcus granulosus cyclins 0.0055 0.0238 0.0238
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0094 0.0887
Echinococcus granulosus neuropeptide FF receptor 2 0.0042 0.0146 0.0146
Schistosoma mansoni integrin alpha-ps 0.0069 0.0336 0.0383
Toxoplasma gondii kringle domain-containing protein 0.0051 0.0211 1
Schistosoma mansoni hypothetical protein 0.0051 0.0211 0.024
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0032 0.0079 0.0675
Echinococcus granulosus G protein coupled receptor 139 0.0042 0.0146 0.0146
Schistosoma mansoni neurotransmitter gated ion channel 0.0237 0.1479 0.1683
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0042 0.0146 0.0166
Loa Loa (eye worm) hypothetical protein 0.0262 0.1651 0.1651
Onchocerca volvulus 0.0042 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0083 0.0428 0.0487
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0042 0.0146 0.0146
Echinococcus multilocularis TGF beta receptor type 1 0.0633 0.4183 0.4183
Schistosoma mansoni twik family of potassium channels-related 0.0032 0.0079 0.009
Schistosoma mansoni ran 0.0024 0.0029 0.0033
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0058 0.0066
Onchocerca volvulus 0.0237 0.1479 0.1479
Onchocerca volvulus 0.0513 0.3367 0.3367
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0053 0.2499
Brugia malayi hypothetical protein 0.0042 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0066 0.0312 0.0355
Leishmania major calcium/potassium channel (CAKC), putative 0.0032 0.0079 0.0756
Brugia malayi G protein-coupled receptor 0.0042 0.0146 0.0146
Echinococcus multilocularis activin receptor type 0.0288 0.1828 0.1828
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0089
Mycobacterium ulcerans ion transport protein 0.0032 0.0079 1
Entamoeba histolytica hypothetical protein 0.004 0.0134 0.0646
Echinococcus granulosus tyrosine protein kinase Fyn 0.0074 0.0369 0.0369
Trichomonas vaginalis cyclin B, putative 0.0132 0.0765 1
Echinococcus granulosus calcium activated potassium channel variant 0.0032 0.0079 0.0079
Plasmodium falciparum cyclin 0.0055 0.0238 1
Echinococcus multilocularis cyclins 0.0055 0.0238 0.0238
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0042 0.0146 0.0166
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0146 0.0166
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Echinococcus granulosus fmrfamide receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Entamoeba histolytica hypothetical protein 0.0277 0.175 1
Loa Loa (eye worm) cyclin domain-containing protein 0.0055 0.0238 0.0238
Echinococcus granulosus tyrosine protein kinase Src42A 0.0065 0.0306 0.0306
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0146 0.0166
Schistosoma mansoni serine-type protease inhibitor 0.1307 0.8787 1
Echinococcus multilocularis twik family of potassium channels 0.0032 0.0079 0.0079
Echinococcus multilocularis glycoprotein Antigen 5 0.0029 0.0058 0.0058
Brugia malayi hypothetical protein 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0042 0.0146 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Trypanosoma cruzi ion transport protein, putative 0.0032 0.0079 0.0675
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Brugia malayi Calcitonin receptor-like protein seb-1 0.0262 0.1651 0.1651
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0146 0.0166
Loa Loa (eye worm) latrophilin receptor protein 2 0.0083 0.0428 0.0428
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0237 0.1479 0.1479
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0513 0.3367 0.3832
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0042 0.0146 0.0166
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0042 0.0146 0.0166
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Echinococcus multilocularis Mastin 0.0029 0.0058 0.0058
Brugia malayi hypothetical protein 0.0042 0.0146 0.0146
Brugia malayi hypothetical protein 0.0029 0.0058 0.0058
Echinococcus multilocularis nAChR subunit 0.0277 0.175 0.175
Loa Loa (eye worm) hypothetical protein 0.0232 0.1444 0.1444
Onchocerca volvulus 0.0042 0.0146 0.0146
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0094 0.0887
Entamoeba histolytica hypothetical protein 0.0027 0.0046 0.0136
Echinococcus multilocularis integrin alpha 3 0.0119 0.0673 0.0673
Schistosoma mansoni neuropeptide F-like receptor 0.0042 0.0146 0.0166
Onchocerca volvulus 0.1031 0.6901 0.6901
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) ACC-1 protein 0.0513 0.3367 0.3367
Echinococcus multilocularis tyrosine protein kinase HCK 0.006 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Schistosoma mansoni biogenic amine (5HT) receptor 0.0042 0.0146 0.0166
Echinococcus granulosus tyrosine protein kinase Src42A 0.0074 0.0369 0.0369
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0042 0.0146 0.0146
Echinococcus granulosus potassium channel subfamily K 8 0.0032 0.0079 0.0079
Echinococcus granulosus tyrosine protein kinase HCK 0.006 0.0269 0.0269
Echinococcus granulosus beta catenin 0.0098 0.0528 0.0528
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0237 0.1479 0.1479
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0262 0.1651 0.1651
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0032 0.0079 0.0079
Schistosoma mansoni tyrosine kinase 0.0074 0.0369 0.042
Onchocerca volvulus 0.0051 0.0211 0.0211
Echinococcus multilocularis serotonin receptor 0.0042 0.0146 0.0146
Echinococcus granulosus integrin alpha 3 0.0119 0.0673 0.0673
Brugia malayi hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0244 0.1528 0.1528
Schistosoma mansoni calcium-activated potassium channel 0.0032 0.0079 0.009
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0513 0.3367 0.3367
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0058 0.0066
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0058
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0046 0.0231
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0513 0.3367 0.3367
Onchocerca volvulus 0.0042 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0042 0.0146 0.0166
Onchocerca volvulus 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0277 0.175 0.175
Onchocerca volvulus 0.0029 0.0058 0.0058
Trichomonas vaginalis cyclin B, putative 0.0132 0.0765 1
Trichomonas vaginalis cyclins, putative 0.009 0.0479 0.6119
Echinococcus multilocularis potassium channel subfamily K 0.0032 0.0079 0.0079
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0032 0.0079 0.0079
Onchocerca volvulus 0.0032 0.0079 0.0079
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0634 0.4189 0.4189
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0029 0.0058 0.0066
Loa Loa (eye worm) neuropeptide F receptor 0.0042 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.004 0.0134 0.0153
Entamoeba histolytica Ran family GTPase 0.0024 0.0029 0.0037
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0277 0.175 0.175
Echinococcus granulosus tachykinin peptides receptor 99D 0.0042 0.0146 0.0146
Schistosoma mansoni tyrosine kinase 0.0074 0.0369 0.042
Echinococcus granulosus glycine receptor subunit beta 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0513 0.3367 0.3367
Onchocerca volvulus 0.0266 0.1676 0.1676
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Echinococcus multilocularis neuroendocrine convertase 2 0.0091 0.048 0.048
Mycobacterium ulcerans transmembrane cation transporter 0.0032 0.0079 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0277 0.175 0.1992
Echinococcus granulosus alpha 1A adrenergic receptor 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0029 0.0058 0.0058
Onchocerca volvulus 0.0026 0.0042 0.0042
Echinococcus granulosus neuroendocrine convertase 2 0.0091 0.048 0.048
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0026 0.0042 0.0042
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0513 0.3367 0.3367
Schistosoma mansoni amine GPCR 0.0042 0.0146 0.0166
Entamoeba histolytica cyclin, putative 0.0055 0.0238 0.1248
Schistosoma mansoni integrin alpha 0.0155 0.092 0.1047
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0032 0.0079 0.0079
Brugia malayi RNA, U transporter 1 0.0095 0.0508 0.0508
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0034 0.0094 0.0107
Schistosoma mansoni importin beta-1 0.0033 0.0089 0.0101
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Schistosoma mansoni amine GPCR 0.0042 0.0146 0.0166
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0237 0.1479 0.1479
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0513 0.3367 0.3367
Schistosoma mansoni hypothetical protein 0.0083 0.0428 0.0487
Echinococcus multilocularis neuropeptide receptor A26 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Toxoplasma gondii hypothetical protein 0.0042 0.0147 0.6963
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Echinococcus granulosus twik family of potassium channels 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Echinococcus multilocularis GPCR, family 2 0.0083 0.0428 0.0428
Schistosoma mansoni alpha-1 adrenergic receptor 0.0042 0.0146 0.0166
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0513 0.3367 0.3367
Schistosoma mansoni adenoreceptor 0.0042 0.0146 0.0166
Trichomonas vaginalis cyclin B, putative 0.0132 0.0765 1
Echinococcus granulosus g protein coupled receptor 0.0042 0.0146 0.0146
Echinococcus granulosus glycoprotein Antigen 5 0.0029 0.0058 0.0058
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0067 0.032 0.032
Echinococcus multilocularis neuropeptides capa receptor 0.0042 0.0146 0.0146
Echinococcus granulosus Furin 1 0.0034 0.0094 0.0094
Echinococcus multilocularis cyclins 0.0055 0.0238 0.0238
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.1485 1 1
Onchocerca volvulus 0.0032 0.0079 0.0079
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0513 0.3367 0.3367
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Loa Loa (eye worm) GABA receptor subunit 0.0277 0.175 0.175
Brugia malayi SRC-1 0.0074 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Brugia malayi hypothetical protein 0.0042 0.0146 0.0146
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0053 0.0321
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0089 0.4176
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0513 0.3367 0.3367
Echinococcus granulosus glycine receptor subunit beta 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Trichomonas vaginalis cyclin B, putative 0.0055 0.0238 0.2843
Plasmodium vivax potassium channel, putative 0.0032 0.0079 0.3731
Echinococcus multilocularis fmrfamide receptor 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0026 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0355 0.2287 0.2603
Brugia malayi Importin beta-1 subunit 0.0033 0.0089 0.0089
Schistosoma mansoni biogenic amine receptor 0.0042 0.0146 0.0166
Brugia malayi RE15519p 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0089
Echinococcus multilocularis glycine receptor subunit beta 0.0513 0.3367 0.3367
Brugia malayi Trypsin-like protease protein 5 0.0029 0.0058 0.0058
Schistosoma mansoni twik family of potassium channels-related 0.0032 0.0079 0.009
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0237 0.1479 0.1479
Schistosoma mansoni neuropeptide F-like receptor 0.0042 0.0146 0.0166
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0032 0.0079 0.009
Onchocerca volvulus 0.0277 0.175 0.175
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Giardia lamblia Furin precursor putative serine protease 0.0028 0.0052 0.0315
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0042 0.0146 0.0146
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0079 0.0675
Echinococcus multilocularis integrin alpha ps 0.0069 0.0336 0.0336
Brugia malayi endoprotease bli-4 precursor 0.0144 0.0846 0.0846
Echinococcus granulosus cyclins 0.0055 0.0238 0.0238
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0042 0.0146 0.0146
Loa Loa (eye worm) neuropeptide F receptor 0.0042 0.0146 0.0146
Brugia malayi neuropeptide F receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Schistosoma mansoni amine GPCR 0.0042 0.0146 0.0166
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0032 0.0079 0.0325
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Onchocerca volvulus 0.0029 0.0058 0.0058
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.1485 1 1
Schistosoma mansoni neuropeptide receptor 0.0546 0.3587 0.4082
Echinococcus granulosus hypothetical protein 0.0042 0.0146 0.0146
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0085 0.0446 0.0446
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0074 0.0369 0.0369
Trichomonas vaginalis cyclin B, putative 0.0132 0.0765 1
Schistosoma mansoni hypothetical protein 0.0083 0.0428 0.0487
Echinococcus granulosus neuropeptide receptor 0.0546 0.3587 0.3587
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0513 0.3367 0.3367
Brugia malayi proprotein convertase 2 0.0091 0.048 0.048
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Echinococcus multilocularis protein will die slowly 0.0066 0.0312 0.0312
Schistosoma mansoni serine-type protease inhibitor 0.1307 0.8787 1
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0032 0.0079 0.0079
Echinococcus granulosus nAChR subunit 0.0513 0.3367 0.3367
Brugia malayi hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Brugia malayi putative neuropeptide receptor NPR1 0.0042 0.0146 0.0146
Leishmania major hypothetical protein, conserved 0.0032 0.0079 0.0756
Echinococcus multilocularis neuropeptide receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0277 0.175 0.175
Onchocerca volvulus Neuropeptide F receptor homolog 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) G-protein coupled receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) WD40 repeat protein 0.0066 0.0312 0.0312
Onchocerca volvulus 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Schistosoma mansoni twik family of potassium channels-related 0.0032 0.0079 0.009
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Trichomonas vaginalis hypothetical protein 0.0028 0.0052 0.0315
Brugia malayi Protein kinase domain containing protein 0.0053 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Brugia malayi Dopamine receptor protein 1 0.0042 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0028 0.0052 0.0059
Echinococcus multilocularis g protein coupled receptor 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0032 0.0079 0.0079
Schistosoma mansoni growth hormone secretagogue receptor 0.0042 0.0146 0.0166
Echinococcus multilocularis g protein coupled receptor 0.0042 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0179 0.1085 0.1235
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0144 0.0846 0.0846
Brugia malayi hypothetical protein 0.0243 0.152 0.152
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0513 0.3367 0.3367
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0029 0.1309
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0042 0.0146 0.0146
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0277 0.175 0.175
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0053 0.0321
Brugia malayi Trypsin family protein 0.0294 0.1872 0.1872
Echinococcus granulosus tissue type plasminogen activator 0.0051 0.0211 0.0211
Loa Loa (eye worm) acetylcholine receptor protein 0.0237 0.1479 0.1479
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0029 0.0029
Echinococcus multilocularis 0.0116 0.0656 0.0656
Plasmodium vivax potassium channel, putative 0.0032 0.0079 0.3731
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0146 0.0166
Loa Loa (eye worm) hypothetical protein 0.0277 0.175 0.175
Trypanosoma cruzi cyclin, putative 0.0132 0.0765 1
Brugia malayi hypothetical protein 0.0237 0.1479 0.1479
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0042 0.0146 0.0146
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0032 0.0079 0.0079
Schistosoma mansoni beta-catenin 0.0098 0.0528 0.0601
Echinococcus granulosus nAChR subunit 0.0277 0.175 0.175
Brugia malayi sulfakinin receptor protein 0.0042 0.0146 0.0146
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0513 0.3367 0.3367
Echinococcus granulosus serotonin receptor 0.0042 0.0146 0.0146
Echinococcus granulosus integrin alpha ps 0.0069 0.0336 0.0336
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Echinococcus granulosus somatostatin receptor 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0513 0.3367 0.3367
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0083 0.0428 0.0428
Loa Loa (eye worm) hypothetical protein 0.0028 0.0053 0.0053
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0053 0.0321
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0042 0.0146 0.0146
Echinococcus multilocularis allatostatin A receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0057 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0042
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0074 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.0277 0.175 0.175
Brugia malayi hypothetical protein 0.0042 0.0146 0.0146
Echinococcus granulosus neuropeptide receptor 0.0042 0.0146 0.0146
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0513 0.3367 0.3367
Echinococcus multilocularis neuropeptide s receptor 0.0042 0.0146 0.0146
Echinococcus granulosus anti dorsalizing morphogenetic protein 1a 0.0064 0.0302 0.0302
Onchocerca volvulus 0.0032 0.0079 0.0079
Onchocerca volvulus 0.0029 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0058
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0091 0.0483 0.0483
Schistosoma mansoni integrin alpha-ps 0.0036 0.0109 0.0124
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Leishmania major potassium channel subunit-like protein 0.0032 0.0079 0.0756
Schistosoma mansoni ran 0.0024 0.0029 0.0033
Brugia malayi Muscle positioning protein 4 0.0026 0.0042 0.0042
Onchocerca volvulus 0.0042 0.0146 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Leishmania major hypothetical protein, conserved 0.0028 0.0053 0.0406
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0132 0.0765 0.0765
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0042 0.0146 0.0146
Echinococcus multilocularis potassium channel subfamily K 8 0.0032 0.0079 0.0079
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0032 0.0079 0.0079
Echinococcus granulosus 7tm_1 domain containing protein 0.0042 0.0146 0.0146
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0237 0.1479 0.1479
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Loa Loa (eye worm) TWK-28 protein 0.0032 0.0079 0.0079
Echinococcus multilocularis neuropeptide Y receptor 0.0042 0.0146 0.0146
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0032 0.0079 0.0079
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0513 0.3367 0.3367
Trichomonas vaginalis WD repeat domain, putative 0.0066 0.0312 0.3848
Echinococcus multilocularis integrin alpha ps 0.0033 0.0089 0.0089
Echinococcus multilocularis sex peptide receptor 0.0042 0.0146 0.0146
Brugia malayi latrophilin 2 splice variant baaae 0.0179 0.1085 0.1085
Entamoeba histolytica cyclin, putative 0.0132 0.0765 0.4295
Echinococcus granulosus cyclin B 0.0132 0.0765 0.0765
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Brugia malayi hypothetical protein 0.0237 0.1479 0.1479
Echinococcus multilocularis neuropeptide FF receptor 2 0.0042 0.0146 0.0146
Echinococcus multilocularis cyclin b3 0.0055 0.0238 0.0238
Echinococcus granulosus Mastin 0.0029 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0883 0.5891 0.6704
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0237 0.1479 0.1479
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0277 0.175 0.175
Loa Loa (eye worm) hypothetical protein 0.0132 0.0765 0.0765
Plasmodium falciparum importin beta, putative 0.0033 0.0089 0.3739
Leishmania major hypothetical protein, conserved 0.0051 0.0211 0.2538
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0042 0.0146 0.0166
Plasmodium falciparum cysteine repeat modular protein 1 0.0051 0.0211 0.8855
Echinococcus multilocularis somatostatin receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0042 0.0146 0.0146
Echinococcus granulosus expressed conserved protein 0.0041 0.014 0.014
Loa Loa (eye worm) uncoordinated protein 58 0.0032 0.0079 0.0079
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0079 0.0675
Trichomonas vaginalis cyclins, putative 0.0055 0.0238 0.2843
Echinococcus multilocularis cyclin B3 1 0.0055 0.0238 0.0238
Onchocerca volvulus 0.0029 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0883 0.5891 0.5891
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Brugia malayi hypothetical protein 0.0237 0.1479 0.1479
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0237 0.1479 0.1479
Echinococcus granulosus tyrosine protein kinase Blk 0.0067 0.032 0.032
Echinococcus granulosus enteropeptidase 0.0029 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0036 0.0109 0.0109
Echinococcus multilocularis neuropeptides capa receptor 0.0042 0.0146 0.0146
Echinococcus multilocularis small conductance calcium activated potassium 0.0883 0.5891 0.5891
Brugia malayi excitatory GABA receptor EXP-1A 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0058
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0074 0.0369 0.0369
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0028 0.0052 0.0315
Loa Loa (eye worm) LGC-31 protein 0.0513 0.3367 0.3367
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0079 0.0675
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Schistosoma mansoni hypothetical protein 0.0029 0.0058 0.0066
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0055 0.0238 0.0238
Echinococcus granulosus beta-adrenergic receptor kinase 0.0091 0.0483 0.0483
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.1031 0.6901 0.7853
Schistosoma mansoni furin-1 (S08 family) 0.0063 0.029 0.033
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0237 0.1479 0.1479
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0513 0.3367 0.3367
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0277 0.175 0.1992
Loa Loa (eye worm) proprotein convertase 2 0.0034 0.0094 0.0094
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0074 0.0369 0.0369
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0117 0.0662 0.0662
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0029 0.1378
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0299 0.1905 0.2168
Echinococcus multilocularis tyrosine protein kinase Blk 0.0067 0.032 0.032
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0237 0.1479 0.1479
Giardia lamblia Cyclin A 0.0055 0.0238 0.2843
Onchocerca volvulus 0.0294 0.1872 0.1872
Onchocerca volvulus 0.0032 0.0079 0.0079
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0513 0.3367 0.3367
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0513 0.3367 0.3832
Leishmania major hypothetical protein, conserved 0.0032 0.0079 0.0756
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0029 0.0029
Trichomonas vaginalis cyclin A, putative 0.0132 0.0765 1
Echinococcus multilocularis fmrfamide receptor 0.0042 0.0146 0.0146
Trichomonas vaginalis cyclins, putative 0.0132 0.0765 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0023 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0237 0.1479 0.1479
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0074 0.0369 0.0369
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0244 0.1528 0.1528
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Leishmania major ion transport protein-like protein 0.0032 0.0079 0.0756
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0042 0.0146 0.0166
Echinococcus granulosus biogenic amine 5HT receptor 0.0042 0.0146 0.0146
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0483 0.055
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0513 0.3367 0.3367
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0042 0.0146 0.0146
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0032 0.0079 0.0675
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Schistosoma mansoni acetylcholine receptor subunit beta 0.0237 0.1479 0.1683
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0032 0.0079 0.0079
Echinococcus granulosus potassium channel subfamily K 8 0.0032 0.0079 0.0079
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0074 0.0369 0.0369
Echinococcus granulosus orexin receptor type 2 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Schistosoma mansoni protein kinase 0.0287 0.1821 0.2072
Schistosoma mansoni calcium-activated potassium channel 0.0032 0.0079 0.009
Echinococcus multilocularis integrin alpha ps 0.0069 0.0336 0.0336
Echinococcus multilocularis snurportin 1 0.0355 0.2287 0.2287
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0042 0.0146 0.0146
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) G-protein coupled receptor 0.0042 0.0146 0.0146
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0053 0.2213
Echinococcus multilocularis beta catenin 0.0098 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.1485 1 1
Loa Loa (eye worm) ACC-1 protein 0.0513 0.3367 0.3367
Onchocerca volvulus 0.0042 0.0146 0.0146
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0042 0.0146 0.0146
Schistosoma mansoni opsin-like receptor 0.0042 0.0146 0.0166
Schistosoma mansoni cyclins 0.0055 0.0238 0.0271
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0029 0.0058 0.0066
Trypanosoma brucei mitotic cyclin 6 0.0132 0.0765 1
Echinococcus multilocularis orexin receptor type 2 0.0042 0.0146 0.0146
Brugia malayi hypothetical protein 0.0032 0.0079 0.0079
Echinococcus multilocularis expressed conserved protein 0.0041 0.014 0.014
Onchocerca volvulus 0.1031 0.6901 0.6901
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0042 0.0146 0.0166
Loa Loa (eye worm) hypothetical protein 0.0277 0.175 0.175
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0026 0.0042 0.0042
Onchocerca volvulus 0.0032 0.0079 0.0079
Schistosoma mansoni biogenic amine receptor 0.0042 0.0146 0.0166
Echinococcus multilocularis dro:myosuppressin receptor 0.0042 0.0146 0.0146
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0029 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0089 0.0816
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0032 0.0079 0.0079
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0513 0.3367 0.3367
Schistosoma mansoni neurotransmitter gated ion channel 0.0277 0.175 0.1992
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Echinococcus multilocularis nAChR subunit 0.0513 0.3367 0.3367
Schistosoma mansoni histamine h1 receptor 0.0042 0.0146 0.0166
Echinococcus multilocularis G-protein coupled receptor, putative 0.0042 0.0146 0.0146
Schistosoma mansoni nAChR subunit 0.0237 0.1479 0.1683
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0053 0.2439
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0237 0.1479 0.1479
Echinococcus granulosus neuropeptide s receptor 0.0042 0.0146 0.0146
Giardia lamblia High cysteine membrane protein Group 2 0.0054 0.0228 0.2699
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0029 0.0029
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0094 0.0887
Brugia malayi Dopamine receptor protein 2 0.0042 0.0146 0.0146
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0058 0.0058
Echinococcus granulosus cyclin b3 0.0055 0.0238 0.0238
Echinococcus granulosus 7TM GPCR rhodopsin 0.0042 0.0146 0.0146
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0074 0.0369 0.0369
Brugia malayi Protein kinase domain containing protein 0.0244 0.1528 0.1528
Brugia malayi Trypsin family protein 0.0029 0.0058 0.0058
Echinococcus multilocularis enteropeptidase 0.0029 0.0058 0.0058
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0042 0.0146 0.0166
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.1485 1 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Onchocerca volvulus 0.0042 0.0146 0.0146
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.1485 1 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Trichomonas vaginalis cyclins, putative 0.0132 0.0765 1
Echinococcus granulosus twik family of potassium channels 0.0032 0.0079 0.0079
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0286 0.1814 0.1814
Echinococcus granulosus cyclin B3 1 0.0055 0.0238 0.0238
Echinococcus granulosus snurportin 1 0.0355 0.2287 0.2287
Echinococcus granulosus protein will die slowly 0.0066 0.0312 0.0312
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0513 0.3367 0.3367
Echinococcus granulosus dro:myosuppressin receptor 0.0042 0.0146 0.0146
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0032 0.0079 1
Brugia malayi GnHR receptor homolog 0.0042 0.0146 0.0146
Brugia malayi Melatonin receptor type 1A 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0079 0.0675
Echinococcus multilocularis neuropeptide receptor 0.0546 0.3587 0.3587
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Entamoeba histolytica hypothetical protein 0.004 0.0134 0.0646
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0042 0.0146 0.0146
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0094 0.0887
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0058 0.0066
Schistosoma mansoni calcium-activated potassium channel 0.0883 0.5891 0.6704
Schistosoma mansoni nAChR subunit 0.0513 0.3367 0.3832
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0083 0.0428 0.0428
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0513 0.3367 0.3367
Brugia malayi ORL1-like opioid receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0794 0.5284 0.5284
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Schistosoma mansoni opsin-like receptor 0.0042 0.0146 0.0166
Echinococcus multilocularis Furin 1 0.0034 0.0094 0.0094
Echinococcus granulosus glycine receptor subunit alpha 1 0.0513 0.3367 0.3367
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0042 0.0146 0.0146
Echinococcus granulosus cyclins 0.0055 0.0238 0.0238
Entamoeba histolytica cyclin family protein 0.0055 0.0238 0.1248
Onchocerca volvulus 0.0513 0.3367 0.3367
Echinococcus granulosus tyrosine protein kinase Lyn 0.0075 0.0377 0.0377
Echinococcus granulosus tyrosine protein kinase Fyn 0.0074 0.0369 0.0369
Onchocerca volvulus 0.0042 0.0146 0.0146
Echinococcus granulosus g-protein coupled receptor 0.0042 0.0146 0.0146
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0023 0.0023
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0032 0.0079 0.0079
Schistosoma mansoni opsin-like receptor 0.0042 0.0146 0.0166
Echinococcus granulosus transmembrane protease serine 3 0.0029 0.0058 0.0058
Schistosoma mansoni cyclin B3 0.0055 0.0238 0.0271
Brugia malayi Serotonin receptor 0.0042 0.0146 0.0146
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0023 0.5
Loa Loa (eye worm) TK protein kinase 0.006 0.0269 0.0269
Schistosoma mansoni neuropeptide f receptor 76f 0.0042 0.0146 0.0166
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0046 0.0231
Echinococcus multilocularis geminin 0.0188 0.1145 0.1145
Schistosoma mansoni biogenic amine receptor 0.0042 0.0146 0.0166
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Toxoplasma gondii ion channel protein 0.0032 0.0079 0.3681
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.1031 0.6901 0.7853
Echinococcus granulosus importin subunit beta 1 0.0033 0.0089 0.0089
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Trypanosoma cruzi ion transport protein, putative 0.0032 0.0079 0.0675
Mycobacterium ulcerans hypothetical protein 0.0029 0.0058 0.6332
Brugia malayi hypothetical protein 0.0042 0.0146 0.0146
Brugia malayi putative neuropeptide receptor 0.0042 0.0146 0.0146
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0058 0.0066
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Echinococcus granulosus tm gpcr rhodopsin 0.0042 0.0146 0.0146
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0277 0.175 0.175
Echinococcus granulosus neuropeptide receptor A26 0.0042 0.0146 0.0146
Brugia malayi bone morphogenetic protein type 1 receptor 0.0634 0.4189 0.4189
Brugia malayi SEA domain containing protein 0.0026 0.0042 0.0042
Echinococcus granulosus potassium channel subfamily K 0.0032 0.0079 0.0079
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0058
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0083 0.0428 0.0428
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0083 0.0428 0.0428
Echinococcus granulosus neuropeptide Y receptor 0.0042 0.0146 0.0146
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0032 0.0079 0.0079
Echinococcus granulosus peptide allatostatin:somatostatin 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0042 0.0146 0.0166
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Schistosoma mansoni twik family of potassium channels-related 0.0032 0.0079 0.009
Schistosoma mansoni neuropeptide receptor 0.0042 0.0146 0.0166
Echinococcus granulosus TGF-beta receptor type-1 0.0633 0.4183 0.4183
Loa Loa (eye worm) HMP-2 protein 0.0098 0.0528 0.0528
Trichomonas vaginalis cyclin B3, putative 0.0055 0.0238 0.2843
Loa Loa (eye worm) TWK-7 protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Brugia malayi Cation transporter family protein 0.0513 0.3367 0.3367
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0032 0.0079 0.0079
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0513 0.3367 0.3367
Onchocerca volvulus 0.0042 0.0146 0.0146
Brugia malayi hypothetical protein 0.0042 0.0146 0.0146
Echinococcus multilocularis cyclins 0.0055 0.0238 0.0238
Brugia malayi protein C17H12.11 0.0243 0.152 0.152
Schistosoma mansoni hypothetical protein 0.0188 0.1145 0.1303
Onchocerca volvulus 0.0066 0.0312 0.0312
Onchocerca volvulus 0.0237 0.1479 0.1479
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0042 0.0146 0.0146
Giardia lamblia Hypothetical protein 0.0032 0.0079 0.0675
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0058
Echinococcus multilocularis cyclin B 0.0132 0.0765 0.0765
Schistosoma mansoni twik family of potassium channels-related 0.0032 0.0079 0.009
Loa Loa (eye worm) hypothetical protein 0.0277 0.175 0.175
Brugia malayi Serotonin receptor 0.0042 0.0146 0.0146
Onchocerca volvulus Putative nachr subunit 0.1485 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0042 0.0146 0.0146
Brugia malayi Cation transporter family protein 0.0513 0.3367 0.3367
Echinococcus multilocularis cyclins 0.0055 0.0238 0.0238
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0042 0.0146 0.0146
Brugia malayi G protein-coupled receptor F59B2.13 0.0042 0.0146 0.0146
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0042 0.0146 0.0166
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0513 0.3367 0.3367
Loa Loa (eye worm) DOMON domain-containing protein 0.0026 0.0042 0.0042
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0088 0.046 0.5859
Brugia malayi celfurPC protein 0.0116 0.0656 0.0656
Brugia malayi Cyclin, N-terminal domain containing protein 0.0132 0.0765 0.0765
Onchocerca volvulus 0.1031 0.6901 0.6901
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0144 0.0846 0.0963
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0237 0.1479 0.1479
Echinococcus granulosus cyclins 0.0055 0.0238 0.0238
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0094 0.0887
Echinococcus granulosus tyrosine protein kinase Src64B 0.0074 0.0369 0.0369
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0042 0.0146 0.0146
Brugia malayi larval opioid receptor 0.0042 0.0146 0.0146
Brugia malayi hypothetical protein 0.004 0.0134 0.0134
Entamoeba histolytica hypothetical protein 0.004 0.0134 0.0646
Echinococcus multilocularis neuropeptide Y receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Brugia malayi Armadillo/beta-catenin-like repeat family protein 0.0098 0.0528 0.0528
Schistosoma mansoni nAChR subunit 0.0513 0.3367 0.3832
Onchocerca volvulus 0.0032 0.0079 0.0079
Toxoplasma gondii ion channel protein 0.0032 0.0079 0.3681
Loa Loa (eye worm) hypothetical protein 0.1031 0.6901 0.6901
Onchocerca volvulus 0.0042 0.0146 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Brugia malayi neuroendocrine convertase 1 precursor 0.0091 0.048 0.048
Loa Loa (eye worm) hypothetical protein 0.1031 0.6901 0.6901
Onchocerca volvulus 0.0024 0.0023 0.0023
Schistosoma mansoni nAChR subunit 0.0513 0.3367 0.3832
Echinococcus multilocularis twik family of potassium channels 0.0032 0.0079 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0238 0.2843
Echinococcus multilocularis anti dorsalizing morphogenetic protein 1a 0.0064 0.0302 0.0302
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0032 0.0079 0.0675
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Brugia malayi Latrophilin receptor protein 2 0.0083 0.0428 0.0428
Brugia malayi protein-tyrosine kinase 0.0067 0.032 0.032
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0513 0.3367 0.3367
Brugia malayi Trypsin family protein 0.0029 0.0058 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0146 0.0166
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0294 0.1872 0.213
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0046 0.0231
Schistosoma mansoni hypothetical protein 0.0083 0.0428 0.0487
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0058 0.0066
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0042 0.0146 0.0146
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0042 0.0146 0.0146
Trypanosoma cruzi CYC2-like cyclin, putative 0.0132 0.0765 1
Echinococcus multilocularis serotonin receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0029 0.0058 0.0058
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0042 0.0146 0.0146
Schistosoma mansoni amine GPCR 0.0042 0.0146 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0134 0.0153
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0023 0.5
Schistosoma mansoni hypothetical protein 0.0042 0.0146 0.0166
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Echinococcus granulosus g protein coupled receptor 0.0042 0.0146 0.0146
Plasmodium falciparum potassium channel 0.0032 0.0079 0.3304
Plasmodium falciparum potassium channel 0.0032 0.0079 0.3304
Schistosoma mansoni twik family of potassium channels-related 0.0032 0.0079 0.009
Echinococcus multilocularis cyclins 0.0055 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0083 0.0428 0.0428
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0088 0.046 0.046
Loa Loa (eye worm) bone morphogenic protein 6 0.0064 0.0302 0.0302
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0134 0.0134
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0032 0.0079 0.0079
Brugia malayi Cyclin, N-terminal domain containing protein 0.0055 0.0238 0.0238
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0029 0.0058 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0211 0.2472
Schistosoma mansoni biogenic amine (5HT) receptor 0.0042 0.0146 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Trichomonas vaginalis cyclin D, putative 0.0055 0.0238 0.2843
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0028 0.0052 0.0315
Schistosoma mansoni hypothetical protein 0.0042 0.0146 0.0166
Schistosoma mansoni nAChR subunit 0.0513 0.3367 0.3832
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0042
Echinococcus granulosus tyrosine kinase 0.0067 0.032 0.032
Brugia malayi neuropeptide F receptor 0.0042 0.0146 0.0146
Schistosoma mansoni calcium-activated potassium channel 0.062 0.4092 0.4657
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) melatonin receptor type 1A 0.0042 0.0146 0.0146
Echinococcus granulosus allatostatin A receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) endoprotease bli-4 0.0144 0.0846 0.0846
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0028 0.0052 0.0315
Loa Loa (eye worm) hypothetical protein 0.0293 0.1863 0.1863
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0513 0.3367 0.3367
Schistosoma mansoni nAChR subunit 0.0513 0.3367 0.3832
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0051 0.0211 1
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0032 0.0079 0.0079
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0023
Echinococcus granulosus sex peptide receptor 0.0042 0.0146 0.0146
Echinococcus granulosus neuropeptide Y receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Echinococcus multilocularis cyclins 0.0055 0.0238 0.0238
Schistosoma mansoni twik family of potassium channels-related 0.0032 0.0079 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Echinococcus granulosus biogenic amine 5HT receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) TK/ROR protein kinase 0.0053 0.0225 0.0225
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0029 0.0058 0.0058
Onchocerca volvulus 0.0026 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Echinococcus granulosus cyclins 0.0055 0.0238 0.0238
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0042 0.0146 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0146 0.0166
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.1485 1 1
Schistosoma mansoni neuropeptide receptor 0.0042 0.0146 0.0166
Echinococcus multilocularis tissue type plasminogen activator 0.0051 0.0211 0.0211
Echinococcus multilocularis calcium activated potassium channel variant 0.0032 0.0079 0.0079
Brugia malayi hypothetical protein 0.0042 0.0146 0.0146
Entamoeba histolytica hypothetical protein 0.004 0.0134 0.0646
Brugia malayi hypothetical protein 0.0237 0.1479 0.1479
Loa Loa (eye worm) TYRA-2 protein 0.0042 0.0146 0.0146
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Brugia malayi Cyclin, N-terminal domain containing protein 0.0132 0.0765 0.0765
Trypanosoma brucei calcium-activated potassium channel, putative 0.0032 0.0079 0.0675
Giardia lamblia Hypothetical protein 0.0055 0.0238 0.2843
Loa Loa (eye worm) hypothetical protein 0.0277 0.175 0.175
Entamoeba histolytica cyclin family protein 0.0055 0.0238 0.1248
Loa Loa (eye worm) SRC-1 0.0074 0.0369 0.0369
Leishmania major GTP-binding protein, putative 0.0024 0.0029 0.0087
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0117 0.0662 0.0662
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0032 0.0079 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Echinococcus granulosus GPCR family 2 0.0083 0.0428 0.0428
Echinococcus granulosus small conductance calcium activated potassium 0.0883 0.5891 0.5891
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0146 0.0166
Trypanosoma cruzi cyclin 6, putative 0.0132 0.0765 1
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0032 0.0079 0.0675
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0088 0.046 0.046
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0023
Onchocerca volvulus 0.0277 0.175 0.175
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Brugia malayi hypothetical protein 0.0028 0.0053 0.0053
Loa Loa (eye worm) trypsin family protein 0.0029 0.0058 0.0058
Brugia malayi Integrin alpha pat-2 precursor 0.0155 0.092 0.092
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0146 0.0166
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0079 0.0675
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0074 0.0369 0.0369
Echinococcus granulosus g protein coupled receptor 0.0042 0.0146 0.0146
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0146 0.0146
Echinococcus granulosus TGF beta receptor type 1 0.0633 0.4183 0.4183
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Echinococcus multilocularis potassium channel subfamily K 8 0.0032 0.0079 0.0079
Echinococcus granulosus furin 0.0144 0.0846 0.0846
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.1485 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0079 0.0675
Schistosoma mansoni myosin xvIII 0.0042 0.0146 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0483 0.055
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0029 0.1221
Echinococcus granulosus neuropeptides capa receptor 0.0042 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0237 0.1479 0.1479
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Echinococcus multilocularis transmembrane protease serine 3 0.0029 0.0058 0.0058
Trichomonas vaginalis cyclins, putative 0.0132 0.0765 1
Schistosoma mansoni nAChR subunit 0.0237 0.1479 0.1683
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Echinococcus multilocularis cyclins 0.0055 0.0238 0.0238
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0046 0.0231
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0262 0.1651 0.1651
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0074 0.0369 0.0369
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0089 0.0816
Schistosoma mansoni hypothetical protein 0.0188 0.1145 0.1303
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0122 0.0693 0.0693
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0513 0.3367 0.3832
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0079
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0042 0.0146 0.0166
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0513 0.3367 0.3367
Schistosoma mansoni neurotransmitter gated ion channel 0.0237 0.1479 0.1683
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0052 0.0315
Onchocerca volvulus 0.0042 0.0146 0.0146
Schistosoma mansoni nAChR subunit 0.0513 0.3367 0.3832
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.1485 1 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0058 0.0066
Brugia malayi Cation transporter family protein 0.1031 0.6901 0.6901
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0042 0.0146 0.0146
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0513 0.3367 0.3832
Trichomonas vaginalis cyclin D, putative 0.0055 0.0238 0.2843
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0277 0.175 0.175
Echinococcus granulosus glycine receptor subunit alpha 1 0.0513 0.3367 0.3367
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0513 0.3367 0.3367
Brugia malayi Will die slowly protein 0.0066 0.0312 0.0312
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0042 0.0146 0.0166
Schistosoma mansoni hypothetical protein 0.0033 0.0089 0.0102
Loa Loa (eye worm) hypothetical protein 0.0294 0.1872 0.1872
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0032 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0146
Brugia malayi hypothetical protein 0.0237 0.1479 0.1479
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0083 0.0428 0.0428
Echinococcus granulosus glycine receptor subunit alpha 1 0.0513 0.3367 0.3367
Loa Loa (eye worm) hypothetical protein 0.0179 0.1085 0.1085
Trypanosoma cruzi cyclin, putative 0.0132 0.0765 1
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0082 0.0419 0.0419

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 12 nM Inhibition of [3H]CP55940 binding to human recombinant CB1 receptor in CHO cells ChEMBL. 17181138
IC50 (binding) = 410 nM Inhibition of [3H]CP55940 binding to human recombinant CB2 receptor in CHO cells ChEMBL. 17181138

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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