Detailed information for compound 1025753

Basic information

Technical information
  • TDR Targets ID: 1025753
  • Name: bis(3-diethylaminopropyl) fluoranthene-3,9-di carboxylate
  • MW: 516.671 | Formula: C32H40N2O4
  • H donors: 0 H acceptors: 2 LogP: 6.46 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCN(CCCOC(=O)c1ccc2c(c1)c1ccc(c3c1c2ccc3)C(=O)OCCCN(CC)CC)CC
  • InChi: 1S/C32H40N2O4/c1-5-33(6-2)18-10-20-37-31(35)23-14-15-24-25-12-9-13-26-28(17-16-27(30(25)26)29(24)22-23)32(36)38-21-11-19-34(7-3)8-4/h9,12-17,22H,5-8,10-11,18-21H2,1-4H3
  • InChiKey: DOWUOKXGWVHVGF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • fluoranthene-3,9-dicarboxylic acid bis(3-diethylaminopropyl) ester
  • 3,9-Fluoranthenedicarboxylic acid, bis[3-(diethylamino)propyl] ester
  • AIDS-192216
  • AIDS192216

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Muscleblind-like protein 0.0151 0.0548 0.145
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0179 0.0675 0.0949
Schistosoma mansoni hypothetical protein 0.0048 0.0083 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0309 0.1264 0.3142
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0179 0.0675 0.0949
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0112 0.037 0.2251
Onchocerca volvulus 0.0048 0.0083 0.0888
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.037 0.0707
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0074 0.0104
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0054 0.0111 0.2256
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0309 0.1264 0.3142
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0112 0.037 0.098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0139 0.0492 0.1086
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1602 0.7111 0.7111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0866 0.378 1
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0139 0.0492 0.1037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0139 0.0492 0.0492
Brugia malayi RNA, U transporter 1 0.0083 0.024 0.0634
Loa Loa (eye worm) hypothetical protein 0.0151 0.0548 0.0865
Loa Loa (eye worm) hypothetical protein 0.0571 0.2448 0.3862
Echinococcus granulosus serine protein kinase ATM 0.0112 0.037 0.037
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0122 0.0415 0.2641
Brugia malayi hypothetical protein 0.0237 0.0937 0.2479
Loa Loa (eye worm) hypothetical protein 0.0112 0.037 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.037 0.0707
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0054 0.0111 0.0111
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0736 0.3195 0.8452
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0139 0.0492 0.3301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0139 0.0492 1
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0866 0.378 1
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0054 0.0111 0.0156
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0179 0.0675 0.4891
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0604 0.2596 0.6773
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0139 0.0492 0.0492
Toxoplasma gondii FATC domain-containing protein 0.0112 0.037 0.5488
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.0937 0.0937
Loa Loa (eye worm) phosphatidylinositol kinase 0.0054 0.0111 0.0175
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0179 0.0675 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0112 0.037 0.0707
Loa Loa (eye worm) phosphatidylinositol 3 0.1431 0.6339 1
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0139 0.0492 1
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0415 0.083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Loa Loa (eye worm) hypothetical protein 0.0294 0.1197 0.1888
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.04 0.1676 0.4265
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0179 0.0675 0.4891
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.037 0.0707
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0169 0.0159
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0811 0.3534 0.9329
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0111 0.0293
Echinococcus multilocularis snurportin 1 0.0311 0.1273 0.1273
Loa Loa (eye worm) hypothetical protein 0.0151 0.0548 0.0865
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0122 0.0415 0.6155
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0255 0.1018 0.2471
Loa Loa (eye worm) hypothetical protein 0.0054 0.0111 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0179 0.0675 0.1537
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0111 0.0293
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0054 0.0111 0.2256
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0571 0.2448 0.6476
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0179 0.0675 0.1609
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0179 0.0675 0.4891
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0139 0.0492 0.1037
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0054 0.0111 0.0111
Echinococcus multilocularis 0.0054 0.0111 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0604 0.2596 0.6773
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Entamoeba histolytica protein kinase rad3, putative 0.0112 0.037 0.0707
Loa Loa (eye worm) phosphatidylinositol 3 0.0179 0.0675 0.1065
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0179 0.0675 0.1609
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0309 0.1264 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.037 0.0707
Echinococcus multilocularis muscleblind protein 0.0151 0.0548 0.0548
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0054 0.0111 0.2256
Onchocerca volvulus 0.0237 0.0939 1
Schistosoma mansoni hypothetical protein 0.0067 0.0169 0.0238
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0111 0.0293
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0309 0.1264 0.3142
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0074 0.0104
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0139 0.0492 0.13
Trypanosoma cruzi hypothetical protein, conserved 0.0775 0.337 0.8882
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0139 0.0492 0.0691
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0179 0.0675 0.0675
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0139 0.0492 0.0691
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0309 0.1264 0.3142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Brugia malayi Pre-SET motif family protein 0.0209 0.0809 0.2139
Schistosoma mansoni survival motor neuron protein 0.0048 0.0083 0.0117
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.0111 0.0175
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.224 1 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0179 0.0675 0.0675
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0112 0.037 0.0707
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0139 0.0492 0.1037
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0074 0.0074
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0139 0.0492 0.1037
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.0809 0.1276
Loa Loa (eye worm) phosphatidylinositol 3 0.0179 0.0675 0.1065
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0139 0.0492 0.1037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0124 0.0036
Giardia lamblia GTOR 0.0179 0.0675 0.3292
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.037 0.0707
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0179 0.0675 0.1609
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0054 0.0111 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0571 0.2448 0.2448
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0179 0.0675 0.1537
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0112 0.037 0.037
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0179 0.0675 0.1537
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1602 0.7111 1
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0225 0.0883 0.4509
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0139 0.0492 0.1037
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0179 0.0675 0.4891
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0112 0.037 0.0707
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0433 0.1824 1
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0067 0.0169 0.0169
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0813 0.3543 0.3543
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0139 0.0492 0.7284
Mycobacterium tuberculosis Conserved hypothetical protein 0.0054 0.0111 0.5
Schistosoma mansoni fkbp-rapamycin associated protein 0.0112 0.037 0.0521
Trichomonas vaginalis PIKK family atypical protein kinase 0.0122 0.0415 0.083
Echinococcus granulosus snurportin 1 0.0311 0.1273 0.1273
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0054 0.0111 0.0156
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.0111 0.0175
Trichomonas vaginalis set domain proteins, putative 0.0237 0.0939 0.2257
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0112 0.037 0.037
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0309 0.1264 0.3142
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0309 0.1264 0.1777
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0179 0.0675 0.0675
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0695 0.3008 0.7895
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0866 0.378 1
Schistosoma mansoni hypothetical protein 0.0054 0.0111 0.0156
Echinococcus multilocularis muscleblind protein 1 0.0151 0.0548 0.0548
Plasmodium vivax hypothetical protein 0.0054 0.0111 0.2256
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0057 0.0124 0.0036
Leishmania major hypothetical protein, conserved 0.0829 0.3617 1
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0866 0.378 1
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0139 0.0492 0.0775
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0139 0.0492 0.0492
Entamoeba histolytica hypothetical protein 0.0112 0.037 0.0707
Loa Loa (eye worm) hypothetical protein 0.0057 0.0124 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0054 0.0111 0.1643
Toxoplasma gondii target of rapamycin (TOR), putative 0.0179 0.0675 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0169 0.0267
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0179 0.0675 0.1609
Onchocerca volvulus 0.0054 0.0111 0.1181
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0866 0.378 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0074 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trypanosoma cruzi target of rapamycin kinase 3 0.0179 0.0675 0.1537
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0074 0.0074
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0054 0.0111 0.1643
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0309 0.1264 0.3343
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0309 0.1264 0.3142
Mycobacterium leprae conserved hypothetical protein 0.0054 0.0111 0.5
Leishmania major phosphatidylinositol 3-kinase, putative 0.0179 0.0675 0.1609
Entamoeba histolytica hypothetical protein 0.0695 0.3008 0.7895
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.0111 0.0175
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0054 0.0111 0.1643
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0311 0.1273 0.2008
Loa Loa (eye worm) hypothetical protein 0.0122 0.0415 0.0655
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0179 0.0675 0.4891
Schistosoma mansoni hypothetical protein 0.0311 0.1273 0.179
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0074 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.037 0.0707
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0083 0.0221
Echinococcus multilocularis Zinc finger, PHD finger 0.0139 0.0492 0.0492
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.0111 0.0175
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0074 0.0074
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0074 0.0117
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0139 0.0492 0.1037
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0179 0.0675 0.1537
Loa Loa (eye worm) phosphatidylinositol 3 0.0255 0.1018 0.1605
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0571 0.2448 0.2448
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0054 0.0111 0.0111
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0074 0.0195
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0054 0.0111 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0112 0.037 0.0521
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.0937 0.0937
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0124 0.0036
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0866 0.378 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0179 0.0675 0.1785
Onchocerca volvulus 0.0054 0.0111 0.1181
Plasmodium vivax hypothetical protein, conserved 0.0054 0.0111 0.2256
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0179 0.0675 0.1785
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0054 0.0111 0.0156
Echinococcus multilocularis serine protein kinase ATM 0.0112 0.037 0.037
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1602 0.7111 0.7111
Leishmania major phosphatidylinositol 3-kinase, putative 0.0139 0.0492 0.1086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.037 0.0707
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0112 0.037 0.098
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0179 0.0675 0.1537
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0179 0.0675 0.1537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0067 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0237 0.0937 0.1478
Echinococcus granulosus muscleblind protein 0.0151 0.0548 0.0548
Brugia malayi FAT domain containing protein 0.0067 0.0169 0.0447
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0139 0.0492 0.7284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.037 0.0707
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0866 0.378 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0179 0.0675 0.1537

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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