Detailed information for compound 1038740

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 290.743 | Formula: C12H19ClN2O4
  • H donors: 2 H acceptors: 5 LogP: 2.2 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(C(=O)O)CCCCCCn1cncc1.Cl
  • InChi: 1S/C12H18N2O4.ClH/c15-11(16)10(12(17)18)5-3-1-2-4-7-14-8-6-13-9-14;/h6,8-10H,1-5,7H2,(H,15,16)(H,17,18);1H
  • InChiKey: RYLQBNSYDNIPLF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens thromboxane A synthase 1 (platelet) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei cytochrome P450, putative thromboxane A synthase 1 (platelet) 534 aa 498 aa 21.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) follicle stimulating hormone receptor 0.001 0.0003 0.0006
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Plasmodium vivax importin-beta 2, putative 0.003 0.0252 0.4183
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.001 0.0003 0.0006
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0081 0.0867 0.0897
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0037
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.001 0.0003 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0447 0.0462
Schistosoma mansoni ran 0.0022 0.0154 0.0159
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0263 0.0272
Leishmania major importin beta-1 subunit, putative 0.0025 0.0182 0.0058
Schistosoma mansoni biogenic amine receptor 0.001 0.0003 0.0003
Echinococcus multilocularis snurportin 1 0.0324 0.3835 0.3835
Schistosoma mansoni amine GPCR 0.001 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0131 0.1478 0.1529
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0263 0.0263
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0239 0.0178
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0336 0.0682
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0182 0.0058
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0309 0.0309
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0348 0.036
Echinococcus multilocularis neuropeptides capa receptor 0.001 0.0003 0.0003
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0081 0.0867 0.0867
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0133 0.0133
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0103 0.0208
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0133 0.027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.027
Echinococcus granulosus importin subunit beta 1 0.003 0.0252 0.026
Onchocerca volvulus 0.0011 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Loa Loa (eye worm) carboxylesterase 0.0066 0.0693 0.1405
Leishmania major serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 0.0413 0.4928 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0309 0.112
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0081 0.0867 0.0867
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0003 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.001 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Schistosoma mansoni amine GPCR 0.001 0.0003 0.0003
Echinococcus multilocularis nAChR subunit 0.0081 0.0867 0.0867
Schistosoma mansoni biogenic amine receptor 0.001 0.0003 0.0003
Echinococcus multilocularis sex peptide receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0597 0.1211
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0133 0.0138
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0011 0.0018 0.0019
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0603 1
Echinococcus granulosus g protein coupled receptor 0.001 0.0003 0.0003
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0042 0.0043
Onchocerca volvulus 0.0059 0.0597 0.1211
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0133 0.027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0133 0.027
Brugia malayi Cation transporter family protein 0.0081 0.0867 0.176
Schistosoma mansoni hypothetical protein 0.001 0.0003 0.0003
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0081 0.0867 0.0897
Echinococcus granulosus neuropeptide FF receptor 2 0.001 0.0003 0.0003
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0252 0.0869
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0336 0.0682
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0309 0.7871
Loa Loa (eye worm) acetyltransferase 0.0141 0.1603 0.3253
Onchocerca volvulus Putative nachr subunit 0.0081 0.0867 0.176
Onchocerca volvulus 0.001 0.0003 0.0006
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0014 0.0015
Brugia malayi hypothetical protein 0.0037 0.0336 0.0682
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0133 0.0138
Onchocerca volvulus 0.0037 0.0336 0.0682
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0603 0.2251
Schistosoma mansoni hypothetical protein 0.042 0.5013 0.5186
Onchocerca volvulus 0.001 0.0003 0.0006
Onchocerca volvulus 0.0035 0.0309 0.0627
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0003 0.0003
Echinococcus granulosus neuroligin 0.0011 0.0018 0.0019
Schistosoma mansoni neuropeptide receptor 0.001 0.0003 0.0003
Onchocerca volvulus 0.001 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0035 0.0309 0.0627
Entamoeba histolytica hypothetical protein 0.0025 0.0182 0.1073
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0081 0.0867 0.176
Mycobacterium ulcerans beta-lactamase 0.0035 0.0309 0.4974
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0011 0.0018 0.0018
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0348 0.1272
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0014 0.0029
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0511
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0133 0.0133
Schistosoma mansoni hypothetical protein 0.0197 0.2284 0.2363
Brugia malayi larval opioid receptor 0.001 0.0003 0.0006
Schistosoma mansoni myosin xvIII 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni nAChR subunit 0.0081 0.0867 0.0897
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0037 0.0336 0.0682
Schistosoma mansoni peptide (allatostatin)-like receptor 0.001 0.0003 0.0003
Brugia malayi TAR-binding protein 0.0131 0.1478 0.2999
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0003 0.0003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0182 0.442
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0133 0.027
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis g protein coupled receptor 0.001 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0003 0.0003
Brugia malayi hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis nAChR subunit 0.0043 0.0412 0.0412
Echinococcus multilocularis glycine receptor subunit beta 0.0081 0.0867 0.0867
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0131 0.1478 0.1529
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0603 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0309 0.112
Schistosoma mansoni hypothetical protein 0.0031 0.0263 0.0272
Schistosoma mansoni ap endonuclease 0.0038 0.0348 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0677
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0263 0.0533
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0133 0.027
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0003 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0133 0.0138
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0447 0.0907
Echinococcus multilocularis fmrfamide receptor 0.001 0.0003 0.0003
Onchocerca volvulus 0.0081 0.0867 0.176
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.001 0.0003 0.0003
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0081 0.0867 0.0867
Loa Loa (eye worm) TYRA-2 protein 0.001 0.0003 0.0006
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0239 0.0178
Brugia malayi Tachykinin-like peptides receptor 99D 0.001 0.0003 0.0006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0447 0.0447
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0133 0.0138
Echinococcus granulosus alpha 1A adrenergic receptor 0.001 0.0003 0.0003
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0081 0.0867 0.176
Schistosoma mansoni hypothetical protein 0.0324 0.3835 0.3967
Schistosoma mansoni hypothetical protein 0.0197 0.2284 0.2363
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0239 0.0178
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0182 0.442
Schistosoma mansoni hypothetical protein 0.004 0.0373 0.0386
Echinococcus multilocularis g protein coupled receptor 0.001 0.0003 0.0003
Onchocerca volvulus 0.001 0.0003 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0003 0.0003
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0133 0.0133
Toxoplasma gondii exonuclease III APE 0.0038 0.0348 0.173
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0081 0.0867 0.176
Echinococcus granulosus peptide allatostatin:somatostatin 0.001 0.0003 0.0003
Brugia malayi ecdysteroid receptor 0.0021 0.0133 0.027
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0706 0.1432
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0014 0.0029
Echinococcus multilocularis muscleblind protein 1 0.0159 0.1826 0.1826
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0037
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0348 0.8939
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0133 0.0138
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0336 0.0682
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.027
Schistosoma mansoni tar DNA-binding protein 0.0131 0.1478 0.1529
Echinococcus multilocularis cpg binding protein 0.0062 0.0637 0.0637
Brugia malayi G-protein coupled receptor 0.001 0.0003 0.0006
Schistosoma mansoni nAChR subunit 0.0081 0.0867 0.0897
Mycobacterium ulcerans hypothetical protein 0.0035 0.0309 0.4974
Onchocerca volvulus 0.001 0.0003 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0677
Schistosoma mansoni nAChR subunit 0.0037 0.0336 0.0348
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0348 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0081 0.0867 0.0897
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.027
Mycobacterium ulcerans lipase LipD 0.0035 0.0309 0.4974
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.001 0.0003 0.0003
Brugia malayi Serotonin receptor 0.001 0.0003 0.0006
Echinococcus granulosus tachykinin peptides receptor 99D 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0037
Echinococcus granulosus dnaJ subfamily B 0.042 0.5013 0.5186
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Schistosoma mansoni histamine h1 receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0159 0.1826 0.3706
Brugia malayi Cation transporter family protein 0.0081 0.0867 0.176
Echinococcus granulosus cpg binding protein 0.0062 0.0637 0.0659
Loa Loa (eye worm) hypothetical protein 0.0413 0.4928 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0309 0.7871
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0133 0.027
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.001 0.0003 0.0003
Schistosoma mansoni family S10 non-peptidase homologue (S10 family) 0.0413 0.4928 0.5098
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0412 0.0427
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0867 0.176
Echinococcus granulosus snurportin 1 0.0324 0.3835 0.3967
Echinococcus multilocularis serotonin receptor 0.001 0.0003 0.0003
Brugia malayi nuclear receptor NHR-88 0.0021 0.0133 0.027
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0447 0.0447
Onchocerca volvulus 0.0175 0.2024 0.4107
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0037 0.0336 0.0336
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0677
Trypanosoma brucei serine peptidase, Clan SC, Family S10 0.0413 0.4928 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0133 0.027
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0154 0.0312
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0081 0.0867 0.176
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0133 0.0133
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.1514 0.3072
Loa Loa (eye worm) hypothetical protein 0.0066 0.0693 0.1405
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Schistosoma mansoni tar DNA-binding protein 0.0131 0.1478 0.1529
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0348 0.7528
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0059 0.0059
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0043 0.0412 0.0427
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0081 0.0867 0.176
Schistosoma mansoni biogenic amine (5HT) receptor 0.001 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0677
Echinococcus granulosus glycine receptor subunit alpha 1 0.0081 0.0867 0.0897
Brugia malayi follicle stimulating hormone receptor 0.001 0.0003 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0677
Trypanosoma brucei serine peptidase, Clan SC, Family S10 0.0413 0.4928 1
Schistosoma mansoni nAChR subunit 0.0081 0.0867 0.0897
Loa Loa (eye worm) TAR-binding protein 0.0131 0.1478 0.2999
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0252 0.0205
Onchocerca volvulus 0.0043 0.0412 0.0837
Loa Loa (eye worm) hypothetical protein 0.0043 0.0412 0.0837
Brugia malayi RNA, U transporter 1 0.0086 0.0934 0.1896
Brugia malayi beta-lactamase 0.0035 0.0309 0.0627
Echinococcus granulosus sex peptide receptor 0.001 0.0003 0.0003
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0037 0.0336 0.0682
Echinococcus granulosus allatostatin A receptor 0.001 0.0003 0.0003
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0373 0.0386
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.001 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0029 0.0239 0.0178
Brugia malayi hypothetical protein 0.001 0.0003 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0133 0.027
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0043 0.0677
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0081 0.0867 0.0897
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0003 0.0003
Echinococcus multilocularis orexin receptor type 2 0.001 0.0003 0.0003
Loa Loa (eye worm) LGC-31 protein 0.0081 0.0867 0.176
Echinococcus granulosus para nitrobenzyl esterase 0.0011 0.0018 0.0019
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.1514 0.3072
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Onchocerca volvulus 0.001 0.0003 0.0006
Echinococcus multilocularis lysosomal protective protein 0.0413 0.4928 0.4928
Loa Loa (eye worm) ACC-1 protein 0.0081 0.0867 0.176
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Onchocerca volvulus 0.0043 0.0412 0.0837
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0043 0.0412 0.0837
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0003 0.0003
Onchocerca volvulus 0.0011 0.0018 0.0037
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0309 0.4974
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Loa Loa (eye worm) RNA binding protein 0.0131 0.1478 0.2999
Trichomonas vaginalis esterase, putative 0.0035 0.0309 0.7871
Schistosoma mansoni biogenic amine (5HT) receptor 0.001 0.0003 0.0003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0133 0.0133
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0133 0.027
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0133 0.027
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0081 0.0867 0.0897
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0081 0.0867 0.0867
Brugia malayi hypothetical protein 0.0037 0.0336 0.0682
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.001 0.0003 0.0006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0447 0.0462
Onchocerca volvulus Uncharacterized serine carboxypeptidase homolog 0.0413 0.4928 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0133 0.027
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0603 0.0623
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0043 0.0412 0.0837
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0081 0.0867 0.0867
Brugia malayi neuropeptide F receptor 0.001 0.0003 0.0006
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0081 0.0867 0.176
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Onchocerca volvulus 0.001 0.0003 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0018 0.0019
Schistosoma mansoni BC026374 protein (S09 family) 0.0011 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0068 0.0706 0.1432
Brugia malayi hypothetical protein 0.0037 0.0336 0.0682
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0081 0.0867 0.176
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0081 0.0867 0.0897
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0018 0.0019
Echinococcus multilocularis tar DNA binding protein 0.0131 0.1478 0.1478
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0677
Brugia malayi Carboxylesterase family protein 0.0011 0.0018 0.0037
Brugia malayi Serine carboxypeptidase F41C3.5 precursor 0.0413 0.4928 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0373 0.0373
Loa Loa (eye worm) hypothetical protein 0.0031 0.0263 0.0533
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0037
Schistosoma mansoni lysosomal protective protein precursor (cathepsin A) (carboxypeptidase 0.0041 0.038 0.0393
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.001 0.0003 0.0003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0348 0.8323
Onchocerca volvulus 0.001 0.0003 0.0006
Echinococcus multilocularis BC026374 protein (S09 family) 0.0011 0.0018 0.0018
Echinococcus multilocularis family S10 non peptidase ue (S10 family) 0.0372 0.4429 0.4429
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0003 0.0003
Brugia malayi RNA binding protein 0.0131 0.1478 0.2999
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0081 0.0867 0.176
Brugia malayi Carboxylesterase family protein 0.0066 0.0693 0.1405
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.001 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0677
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0037
Echinococcus multilocularis dro:myosuppressin receptor 0.001 0.0003 0.0003
Echinococcus granulosus tar DNA binding protein 0.0131 0.1478 0.1529
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Trichomonas vaginalis helicase, putative 0.0013 0.0043 0.0677
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0133 0.0138
Loa Loa (eye worm) hypothetical protein 0.0099 0.1087 0.2206
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0239 0.3629
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0447 0.0907
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis glycine receptor subunit beta 0.0081 0.0867 0.0867
Loa Loa (eye worm) hypothetical protein 0.0159 0.1826 0.3706
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0677
Schistosoma mansoni cpg binding protein 0.0062 0.0637 0.0659
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0037 0.0336 0.0348
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.027
Onchocerca volvulus 0.001 0.0003 0.0006
Echinococcus granulosus hypothetical protein 0.001 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0035 0.0309 0.0325
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0103 0.0106
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0309 0.6636
Brugia malayi Dopamine receptor 0.001 0.0003 0.0006
Echinococcus granulosus acetylcholinesterase 0.0066 0.0693 0.0717
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0037 0.0336 0.0682
Loa Loa (eye worm) hypothetical protein 0.0043 0.0412 0.0837
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0003 0.0003
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0081 0.0867 0.176
Brugia malayi AKH receptor 0.001 0.0003 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0003 0.0003
Echinococcus multilocularis neuroligin 0.0011 0.0018 0.0018
Brugia malayi Muscleblind-like protein 0.0159 0.1826 0.3706
Schistosoma mansoni tar DNA-binding protein 0.0131 0.1478 0.1529
Echinococcus multilocularis fmrfamide receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni nAChR subunit 0.0081 0.0867 0.0897
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0447 0.0462
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0133 0.027
Brugia malayi hypothetical protein 0.0037 0.0336 0.0682
Echinococcus multilocularis geminin 0.0197 0.2284 0.2284
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0693 0.0693
Onchocerca volvulus 0.001 0.0003 0.0006
Echinococcus multilocularis para nitrobenzyl esterase 0.0011 0.0018 0.0018
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0348 1
Brugia malayi hypothetical protein 0.004 0.0373 0.0758
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0081 0.0867 0.176
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0309 0.112
Loa Loa (eye worm) ACC-1 protein 0.0081 0.0867 0.176
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0388 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0867 0.176
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0003 0.0003
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0133 0.027
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0309 0.112
Loa Loa (eye worm) hypothetical protein 0.0043 0.0412 0.0837
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0867 0.176
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0037
Loa Loa (eye worm) carboxylesterase 0.0011 0.0018 0.0037
Brugia malayi nuclear hormone receptor 0.0021 0.0133 0.027
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0131 0.1478 0.2999
Brugia malayi Importin beta-1 subunit 0.003 0.0252 0.0511
Schistosoma mansoni neurotransmitter gated ion channel 0.0037 0.0336 0.0348
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0447 0.0462
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0133 0.0138
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.027
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0081 0.0867 0.0867
Schistosoma mansoni cpg binding protein 0.0059 0.0597 0.0617
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0003 0.0003
Brugia malayi Dopamine receptor protein 2 0.001 0.0003 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0133 0.027
Brugia malayi gonadotropin-releasing hormone receptor 2 0.001 0.0003 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0677
Schistosoma mansoni nAChR subunit 0.0081 0.0867 0.0897
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.001 0.0003 0.0003
Onchocerca volvulus 0.0081 0.0867 0.176
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0133 0.027
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0003 0.0003
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0037 0.0336 0.0348
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0081 0.0867 0.0867
Echinococcus multilocularis importin subunit beta 1 0.003 0.0252 0.0252
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0133 0.0138
Echinococcus multilocularis serotonin receptor 0.001 0.0003 0.0003
Schistosoma mansoni neuropeptide F-like receptor 0.001 0.0003 0.0003
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0133 0.0138
Echinococcus granulosus neuropeptides capa receptor 0.001 0.0003 0.0003
Echinococcus granulosus carboxylesterase 5A 0.0066 0.0693 0.0717
Echinococcus granulosus neuropeptide s receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis g protein coupled receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Brugia malayi hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni hypothetical protein 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0239 0.0484
Onchocerca volvulus 0.001 0.0003 0.0006
Schistosoma mansoni opsin-like receptor 0.001 0.0003 0.0003
Plasmodium falciparum importin beta, putative 0.003 0.0252 0.5025
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0081 0.0867 0.0897
Schistosoma mansoni importin beta-1 0.003 0.0252 0.026
Brugia malayi nuclear receptor RXR 0.0011 0.0014 0.0029
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0014 0.0015
Echinococcus multilocularis G protein coupled receptor 139 0.001 0.0003 0.0003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0309 0.032
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0154 0.0312
Loa Loa (eye worm) hypothetical protein 0.0035 0.0309 0.0627
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0309 0.0325
Schistosoma mansoni amine GPCR 0.001 0.0003 0.0003
Brugia malayi Melatonin receptor type 1A 0.001 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.1087 0.2206
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Trypanosoma cruzi serine peptidase, Clan SC, Family S10, putative 0.0413 0.4928 1
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0133 0.0138
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0345 0.9846
Schistosoma mansoni nAChR subunit 0.0081 0.0867 0.0897
Entamoeba histolytica hypothetical protein 0.004 0.0373 0.8491
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.1603 0.1603
Schistosoma mansoni neuropeptide receptor 0.001 0.0003 0.0003
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.001 0.0003 0.0003
Onchocerca volvulus 0.001 0.0003 0.0006
Brugia malayi excitatory GABA receptor EXP-1A 0.0081 0.0867 0.176
Echinococcus granulosus family S10 non peptidase ue S10 family 0.0372 0.4429 0.4582
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0309 0.7871
Echinococcus granulosus dro:myosuppressin receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Mycobacterium tuberculosis Conserved protein 0.0035 0.0309 0.112
Loa Loa (eye worm) hypothetical protein 0.0043 0.0412 0.0837
Echinococcus granulosus G protein coupled receptor 139 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.027
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0133 0.0138
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0309 0.4974
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0081 0.0867 0.0897
Brugia malayi GnHR receptor homolog 0.001 0.0003 0.0006
Loa Loa (eye worm) melatonin receptor type 1A 0.001 0.0003 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0133 0.027
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0412 0.0837
Schistosoma mansoni nAChR subunit 0.0081 0.0867 0.0897
Loa Loa (eye worm) hypothetical protein 0.0066 0.0693 0.1405
Brugia malayi Cation transporter family protein 0.0081 0.0867 0.176
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0309 0.7871
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0031 0.0263 0.0272
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0154 0.0159
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.01 0.0202
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni cpg binding protein 0.0062 0.0637 0.0659
Schistosoma mansoni acetylcholinesterase 0.0011 0.0018 0.0019
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0133 0.0133
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0345 0.7412
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0603 0.0623
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0003 0.0003
Schistosoma mansoni ap endonuclease 0.0038 0.0348 0.036
Echinococcus granulosus neuropeptide receptor A26 0.001 0.0003 0.0003
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0345 0.9846
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0037 0.0336 0.0682
Trichomonas vaginalis ran, putative 0.0022 0.0154 0.3669
Schistosoma mansoni growth hormone secretagogue receptor 0.001 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0003 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0447 0.0462
Brugia malayi putative neuropeptide receptor 0.001 0.0003 0.0006
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0263 0.0263
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0348 0.5
Brugia malayi steroid hormone receptor 0.0021 0.0133 0.027
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Echinococcus granulosus neuropeptide Y receptor 0.001 0.0003 0.0003
Echinococcus multilocularis neuropeptide receptor 0.001 0.0003 0.0003
Schistosoma mansoni amine GPCR 0.001 0.0003 0.0003
Schistosoma mansoni neuroligin 3 (S09 family) 0.0011 0.0018 0.0019
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0348 0.5
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0182 0.442
Loa Loa (eye worm) neuropeptide F receptor 0.001 0.0003 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0003 0.0003
Brugia malayi MH2 domain containing protein 0.0134 0.1514 0.3072
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0133 0.0138
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0014 0.0015
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0133 0.027
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0309 0.112
Brugia malayi hypothetical protein 0.001 0.0003 0.0006
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0081 0.0867 0.0897
Schistosoma mansoni hypothetical protein 0.001 0.0003 0.0003
Echinococcus multilocularis neuropeptide FF receptor 2 0.001 0.0003 0.0003
Onchocerca volvulus 0.0021 0.0133 0.027
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0309 0.5
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0309 0.7871
Loa Loa (eye worm) carboxylesterase 0.0011 0.0018 0.0037
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0677
Echinococcus multilocularis biogenic amine (5HT) receptor 0.001 0.0003 0.0003
Echinococcus granulosus orexin receptor type 2 0.001 0.0003 0.0003
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0175 0.2024 0.4107
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.0003 0.0003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0309 0.032
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus granulosus g protein coupled receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0348 0.0707
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0133 0.0138
Echinococcus granulosus BC026374 protein S09 family 0.0011 0.0018 0.0019
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0388 0.2078
Loa Loa (eye worm) acetylcholinesterase 1 0.0066 0.0693 0.1405
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni alpha-1 adrenergic receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Onchocerca volvulus 0.0011 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0309 0.112
Onchocerca volvulus 0.001 0.0003 0.0006
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.001 0.0003 0.0003
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.001 0.0003 0.0003
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0037 0.0336 0.0682
Brugia malayi Carboxylesterase family protein 0.0011 0.0018 0.0037
Trypanosoma cruzi serine carboxypeptidase (CBP1), putative 0.0413 0.4928 1
Schistosoma mansoni gliotactin 0.0011 0.0018 0.0019
Echinococcus granulosus nAChR subunit 0.0081 0.0867 0.0897
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0.0003 0.0003
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0603 0.094
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0003 0.0003
Brugia malayi neuropeptide F receptor 0.001 0.0003 0.0006
Echinococcus granulosus g-protein coupled receptor 0.001 0.0003 0.0003
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0603 0.0603
Brugia malayi hypothetical protein 0.001 0.0003 0.0006
Echinococcus granulosus 7tm_1 domain containing protein 0.001 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0133 0.027
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0037
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0081 0.0867 0.176
Echinococcus multilocularis GPCR, family 2 0.0031 0.0263 0.0263
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0133 0.027
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0133 0.0138
Echinococcus granulosus somatostatin receptor 0.001 0.0003 0.0003
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0059 0.0061
Onchocerca volvulus 0.0037 0.0336 0.0682
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0133 0.027
Onchocerca volvulus 0.0035 0.0309 0.0627
Onchocerca volvulus Neuropeptide F receptor homolog 0.001 0.0003 0.0006
Schistosoma mansoni acetylcholine receptor subunit beta 0.0037 0.0336 0.0348
Echinococcus granulosus GPCR family 2 0.0031 0.0263 0.0272
Onchocerca volvulus 0.001 0.0003 0.0006
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0133 0.0138
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0059 0.0061
Brugia malayi putative neuropeptide receptor NPR1 0.001 0.0003 0.0006
Brugia malayi G-protein coupled receptor 0.001 0.0003 0.0006
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0309 0.0627
Entamoeba histolytica hypothetical protein 0.004 0.0373 0.8491
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Echinococcus granulosus fmrfamide receptor 0.001 0.0003 0.0003
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0309 0.112
Brugia malayi Cytochrome P450 family protein 0.0026 0.0201 0.0408
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.001 0.0003 0.0006
Brugia malayi hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni coup transcription factor 0.0021 0.0133 0.0138
Echinococcus multilocularis g-protein coupled receptor 0.001 0.0003 0.0003
Onchocerca volvulus 0.0081 0.0867 0.176
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0037 0.0336 0.0336
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0059 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0133 0.027
Schistosoma mansoni neuropeptide F-like receptor 0.001 0.0003 0.0003
Brugia malayi hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis somatostatin receptor 0.001 0.0003 0.0003
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.001 0.0003 0.0003
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0309 0.112
Echinococcus granulosus glycine receptor subunit beta 0.0081 0.0867 0.0897
Loa Loa (eye worm) hypothetical protein 0.0035 0.0309 0.0627
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0081 0.0867 0.0897
Onchocerca volvulus 0.0037 0.0336 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0677
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.1555 0.1609
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0059 0.0059
Brugia malayi hypothetical protein 0.0011 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0603 0.399
Schistosoma mansoni neuropeptide receptor 0.001 0.0003 0.0003
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0133 0.0138
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0081 0.0867 0.0867
Echinococcus granulosus glycine receptor subunit alpha 1 0.0081 0.0867 0.0897
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0133 0.0133
Echinococcus granulosus microtubule associated protein 2 0.0801 0.9666 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0133 0.027
Brugia malayi Serotonin/octopamine receptor family protein 7 0.001 0.0003 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.1603 0.3253
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0324 0.3835 0.7782
Schistosoma mansoni opsin-like receptor 0.001 0.0003 0.0003
Brugia malayi hypothetical protein 0.0037 0.0336 0.0682
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0081 0.0867 0.176
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0239 0.0754
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0003 0.0003
Brugia malayi hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis G-protein coupled receptor, putative 0.001 0.0003 0.0003
Loa Loa (eye worm) neuropeptide F receptor 0.001 0.0003 0.0006
Echinococcus multilocularis allatostatin A receptor 0.001 0.0003 0.0003
Echinococcus multilocularis tachykinin peptides receptor 99D 0.001 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0133 0.027
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0309 0.0325
Echinococcus multilocularis neuropeptide s receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0043 0.0412 0.0837
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0.0003 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0603 0.0623
Schistosoma mansoni neurotransmitter gated ion channel 0.0037 0.0336 0.0348
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0081 0.0867 0.0897
Echinococcus multilocularis neuropeptide Y receptor 0.001 0.0003 0.0003
Brugia malayi Carboxylesterase family protein 0.0011 0.0018 0.0037
Echinococcus multilocularis muscleblind protein 0.0159 0.1826 0.1826
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Brugia malayi Carboxylesterase family protein 0.0011 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Onchocerca volvulus 0.0011 0.0018 0.0037
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0388 1
Onchocerca volvulus 0.0035 0.0309 0.0627
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.001 0.0003 0.0003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0133 0.0138
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.001 0.0003 0.0006
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0133 0.0138
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.001 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0867 0.176
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0348 0.0348
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0867 0.176
Brugia malayi hypothetical protein 0.0011 0.0014 0.0029
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0103 0.0103
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0388 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0081 0.0867 0.0897
Schistosoma mansoni hypothetical protein 0.0031 0.0263 0.0272
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0693 0.0693
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0867 0.176
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0263 0.0533
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0677
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0133 0.027
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0043 0.0412 0.0837
Echinococcus granulosus acetylcholinesterase 0.0066 0.0693 0.0717
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0348 0.0408
Brugia malayi RE15519p 0.001 0.0003 0.0006
Schistosoma mansoni hypothetical protein 0.0068 0.0706 0.073
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0029
Schistosoma mansoni family S10 unassigned peptidase (S10 family) 0.0413 0.4928 0.5098
Loa Loa (eye worm) acetylcholine receptor protein 0.0037 0.0336 0.0682
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0133 0.027
Echinococcus granulosus geminin 0.0197 0.2284 0.2363
Onchocerca volvulus 0.001 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0029
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis neuropeptide receptor 0.001 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0133 0.027
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0309 0.0627
Onchocerca volvulus 0.0011 0.0018 0.0037
Onchocerca volvulus 0.001 0.0003 0.0006
Echinococcus multilocularis dnaJ subfamily B 0.042 0.5013 0.5013
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0037 0.0336 0.0336
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0309 0.032
Schistosoma mansoni neuropeptide receptor 0.001 0.0003 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0003 0.0003
Brugia malayi beta-lactamase family protein 0.0035 0.0309 0.0627
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0239 0.436
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0043 0.0677
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0388 0.0401
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0348 0.0408
Schistosoma mansoni hypothetical protein 0.0031 0.0263 0.0272
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.1087 0.2206
Echinococcus granulosus g protein coupled receptor 0.001 0.0003 0.0003
Echinococcus multilocularis neuropeptides capa receptor 0.001 0.0003 0.0003
Brugia malayi hypothetical protein 0.0029 0.0239 0.0484
Entamoeba histolytica hypothetical protein 0.004 0.0373 0.8491
Loa Loa (eye worm) G-protein coupled receptor 0.001 0.0003 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0003 0.0003
Brugia malayi RNA recognition motif domain containing protein 0.0131 0.1478 0.2999
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.027
Brugia malayi Dopamine receptor protein 1 0.001 0.0003 0.0006
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0263 0.0533
Echinococcus multilocularis neuropeptide Y receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.001 0.0003 0.0006
Schistosoma mansoni opsin-like receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0029
Schistosoma mansoni ran 0.0022 0.0154 0.0159
Echinococcus granulosus neuropeptide Y receptor 0.001 0.0003 0.0003
Echinococcus granulosus lysosomal protective protein 0.0413 0.4928 0.5098
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0081 0.0867 0.176
Schistosoma mansoni amine GPCR 0.001 0.0003 0.0003
Schistosoma mansoni nAChR subunit 0.0037 0.0336 0.0348
Toxoplasma gondii ABC1 family protein 0.0035 0.0309 0.1379
Echinococcus granulosus serotonin receptor 0.001 0.0003 0.0003
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0309 0.0627
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0388 0.2078
Brugia malayi G protein-coupled receptor 0.001 0.0003 0.0006
Loa Loa (eye worm) GABA receptor subunit 0.0043 0.0412 0.0837
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0066 0.0693 0.0717
Brugia malayi CXXC zinc finger family protein 0.0059 0.0597 0.1211
Mycobacterium leprae Probable lipase LipE 0.0035 0.0309 0.5
Brugia malayi Carboxylesterase family protein 0.0066 0.0693 0.1405
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.001 0.0003 0.0003
Echinococcus granulosus neuropeptides capa receptor 0.001 0.0003 0.0003
Brugia malayi beta-lactamase family protein 0.0035 0.0309 0.0627
Brugia malayi hypothetical protein 0.001 0.0003 0.0006
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0081 0.0867 0.176
Schistosoma mansoni acetylcholine receptor-related 0.0037 0.0336 0.0348
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.1399 0.1447
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0252 0.0205
Echinococcus granulosus glycine receptor subunit alpha 1 0.0081 0.0867 0.0897
Brugia malayi sulfakinin receptor protein 0.001 0.0003 0.0006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0.0003 0.0003
Onchocerca volvulus 0.0081 0.0867 0.176
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0412 0.0837
Trypanosoma brucei serine peptidase, Clan SC, Family S10 0.0413 0.4928 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0133 0.0138
Brugia malayi hypothetical protein 0.0175 0.2024 0.4107
Trypanosoma cruzi serine peptidase, Clan SC, Family S10, putative 0.0413 0.4928 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0043 0.0677
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0081 0.0867 0.176
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0133 0.0133
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0.0003 0.0003
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0348 0.0408
Schistosoma mansoni hypothetical protein 0.001 0.0003 0.0003
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0263 0.0272
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.027
Echinococcus granulosus 7TM GPCR rhodopsin 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0043 0.0412 0.0837
Schistosoma mansoni neuropeptide f receptor 76f 0.001 0.0003 0.0003
Echinococcus granulosus glycine receptor subunit beta 0.0081 0.0867 0.0897
Onchocerca volvulus 0.0081 0.0867 0.176
Echinococcus granulosus neuropeptide receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0043 0.0412 0.0837
Loa Loa (eye worm) hypothetical protein 0.0043 0.0412 0.0837
Schistosoma mansoni adenoreceptor 0.001 0.0003 0.0003
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0348 0.5649
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0081 0.0867 0.0867
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.1279 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.001 0.0003 0.0006
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0081 0.0867 0.176
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.1603 0.1658
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Brugia malayi ORL1-like opioid receptor 0.001 0.0003 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0.0003 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0603 1
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0348 0.0707
Echinococcus granulosus muscleblind protein 0.0159 0.1826 0.1889
Brugia malayi hypothetical protein 0.001 0.0003 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0309 0.0325
Echinococcus granulosus nAChR subunit 0.0043 0.0412 0.0427
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0348 0.8939
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0029
Brugia malayi G protein-coupled receptor F59B2.13 0.001 0.0003 0.0006
Brugia malayi hypothetical protein 0.0011 0.0014 0.0029
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0309 0.112
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.1087 0.2206
Schistosoma mansoni hypothetical protein 0.0013 0.0042 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0133 0.0138
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0239 0.436
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0081 0.0867 0.0867
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.001 0.0003 0.0003
Echinococcus granulosus neuropeptide receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0014 0.0029
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Schistosoma mansoni biogenic amine receptor 0.001 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0043 0.0412 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.2614 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0133 0.0138
Loa Loa (eye worm) beta-lactamase 0.0035 0.0309 0.0627
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0003 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0043 0.0677
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0081 0.0867 0.0897
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0081 0.0867 0.0897
Onchocerca volvulus 0.001 0.0003 0.0006
Trypanosoma cruzi serine carboxypeptidase (CBP1), putative 0.0413 0.4928 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.001 0.0003 0.0003
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0309 0.0627
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Onchocerca volvulus 0.0081 0.0867 0.176
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0348 0.0408
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0003 0.0003
Brugia malayi hypothetical protein 0.0019 0.0112 0.0227
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0201 0.0408
Entamoeba histolytica hypothetical protein 0.004 0.0373 0.8491
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.176
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0011 0.0018 0.0019
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0373 0.0386
Echinococcus multilocularis neuropeptide receptor A26 0.001 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0133 0.027
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.001 0.0003 0.0006
Echinococcus multilocularis carboxylesterase 5A 0.0066 0.0693 0.0693
Brugia malayi Serotonin receptor 0.001 0.0003 0.0006
Schistosoma mansoni neurotransmitter gated ion channel 0.0043 0.0412 0.0427
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.001 0.0003 0.0003
Echinococcus multilocularis microtubule associated protein 2 0.0801 0.9666 0.9666
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0042 0.0042
Echinococcus multilocularis alpha 1A adrenergic receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0336 0.0682
Loa Loa (eye worm) hypothetical protein 0.0035 0.0309 0.0627
Schistosoma mansoni microtubule-associated protein tau 0.0801 0.9666 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 550 nM Inhibitory activity against human thromboxane synthetase ChEMBL. 7199088

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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