Detailed information for compound 1128523

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 410.491 | Formula: C17H26N6O4S
  • H donors: 6 H acceptors: 4 LogP: -0.63 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: SCC(=O)N[C@H](C(=O)N[C@H](C(=O)N)CCCNC(=N)N)Cc1ccc(cc1)O
  • InChi: 1S/C17H26N6O4S/c18-15(26)12(2-1-7-21-17(19)20)23-16(27)13(22-14(25)9-28)8-10-3-5-11(24)6-4-10/h3-6,12-13,24,28H,1-2,7-9H2,(H2,18,26)(H,22,25)(H,23,27)(H4,19,20,21)/t12-,13-/m0/s1
  • InChiKey: YQDPQKFAQMPBML-STQMWFEESA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Pseudolysin Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0038 0.0141 0.115
Echinococcus granulosus intermediate filament protein 0.0085 0.0625 0.0594
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0096 0.6844
Loa Loa (eye worm) hypothetical protein 0.0046 0.0224 0.0585
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0075 0.0519 0.572
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0113 0.0907 0.0877
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0141 0.0236
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0141 0.0368
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0113 0.0907 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0175 0.0143
Loa Loa (eye worm) intermediate filament protein 0.0085 0.0625 0.1632
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0033 0.0087
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.0862 0.225
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0096 0.0161
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0221 0.0578
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0143 0.1571
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0141 0.0236
Echinococcus multilocularis lamin 0.0085 0.0625 0.0594
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0224 0.1829
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0136 0.01
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0136 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0224 0.1668
Giardia lamblia Kinase, PLK 0.0113 0.0907 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0113 0.0907 0.7406
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0143 0.0674
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0143 0.1571
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0326 0.2908
Echinococcus granulosus lysosomal alpha glucosidase 0.0171 0.1499 0.1471
Echinococcus granulosus neuropeptide receptor A26 0.1006 1 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0136 0.5578
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0141 0.0654
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0141 0.0159
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0512 0.1336
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0175 0.0143
Onchocerca volvulus Huntingtin homolog 0.0144 0.1225 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0113 0.0907 0.2369
Loa Loa (eye worm) hypothetical protein 0.0085 0.0625 0.1632
Echinococcus multilocularis chromobox protein 1 0.0082 0.0591 0.056
Loa Loa (eye worm) heterochromatin protein 1 0.0082 0.0591 0.1544
Onchocerca volvulus 0.0085 0.0625 0.5103
Loa Loa (eye worm) hypothetical protein 0.004 0.0159 0.0416
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0106 0.0073
Onchocerca volvulus 0.0099 0.0764 0.6237
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0141 0.0108
Mycobacterium leprae Probable lipase LipE 0.0038 0.0141 1
Trichomonas vaginalis chromobox protein, putative 0.0082 0.0591 0.6146
Schistosoma mansoni inositol monophosphatase 0.0037 0.0136 0.0577
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0143 0.0674
Echinococcus granulosus GPCR family 2 0.0034 0.0106 0.0073
Mycobacterium ulcerans lipase LipD 0.0038 0.0141 1
Brugia malayi MH2 domain containing protein 0.04 0.383 1
Mycobacterium ulcerans hypothetical protein 0.0038 0.0141 1
Schistosoma mansoni hypothetical protein 0.0034 0.0106 0.0405
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0141 0.0236
Loa Loa (eye worm) follicle stimulating hormone receptor 0.024 0.2196 0.5733
Schistosoma mansoni inositol monophosphatase 0.0037 0.0136 0.0577
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0143 0.0179
Brugia malayi beta-lactamase 0.0038 0.0141 0.0368
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0106 0.0073
Loa Loa (eye worm) hypothetical protein 0.0084 0.0609 0.1591
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0519 0.5013
Brugia malayi MH1 domain containing protein 0.0027 0.0033 0.0087
Brugia malayi chromobox protein homolog 3 0.0046 0.0224 0.0585
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0519 0.5013
Brugia malayi MH1 domain containing protein 0.0027 0.0033 0.0087
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0106 0.0276
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0136 0.1503
Loa Loa (eye worm) inositol-1 0.0037 0.0136 0.0356
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0136 0.01
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0033 0.0087
Toxoplasma gondii ABC1 family protein 0.0038 0.0141 0.8862
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0141 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.0862 0.225
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0141 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0113 0.0907 0.2369
Leishmania major hypothetical protein, conserved 0.0038 0.0141 0.1553
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0141 0.0602
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0075 0.0519 0.0487
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0075 0.0519 0.572
Loa Loa (eye worm) hypothetical protein 0.0038 0.0141 0.0368
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.026 0.2119
Schistosoma mansoni alpha glucosidase 0.0038 0.0143 0.0611
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0326 0.2908
Entamoeba histolytica serine/threonine protein kinase, putative 0.0113 0.0907 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0519 0.5264
Loa Loa (eye worm) hypothetical protein 0.0038 0.0141 0.0368
Mycobacterium tuberculosis Possible exported protein 0.0612 0.5982 1
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0136 0.0104
Trypanosoma cruzi polo-like protein kinase, putative 0.0113 0.0907 1
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0141 0.0654
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0054 0.0304 0.0794
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0907 1
Onchocerca volvulus 0.0038 0.0141 0.115
Loa Loa (eye worm) Smad1 0.0027 0.0033 0.0087
Brugia malayi Smad1 0.0027 0.0033 0.0087
Loa Loa (eye worm) hypothetical protein 0.0144 0.1225 0.3199
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0304 0.1516
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0141 1
Schistosoma mansoni hypothetical protein 0.0034 0.0106 0.0405
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0907 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0519 0.1355
Loa Loa (eye worm) hypothetical protein 0.0036 0.0123 0.0321
Brugia malayi hypothetical protein 0.0144 0.1225 0.3199
Brugia malayi MH2 domain containing protein 0.0027 0.0033 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0143 0.0179
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0106 0.0276
Mycobacterium tuberculosis Conserved protein 0.0038 0.0141 0.0236
Loa Loa (eye worm) hypothetical protein 0.0109 0.0862 0.225
Mycobacterium tuberculosis Conserved protein 0.0038 0.0141 0.0236
Schistosoma mansoni hypothetical protein 0.0203 0.1822 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0304 0.1516
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0141 0.0654
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0143 0.0372
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0143 0.0674
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0141 0.0108
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0075 0.0519 0.2716
Onchocerca volvulus Huntingtin homolog 0.0144 0.1225 1
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0106 0.0276
Trichomonas vaginalis chromobox protein, putative 0.0082 0.0591 0.6146
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0141 1
Loa Loa (eye worm) hepatopoietin HPO2 0.0037 0.0129 0.0336
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0907 1
Leishmania major hypothetical protein, conserved 0.0037 0.0129 0.1417
Brugia malayi intermediate filament protein 0.0085 0.0625 0.1632
Brugia malayi Heterochromatin protein 1 0.0082 0.0591 0.1544
Trypanosoma cruzi polo-like protein kinase, putative 0.0113 0.0907 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0143 0.0674
Echinococcus granulosus lamin dm0 0.0085 0.0625 0.0594
Schistosoma mansoni hypothetical protein 0.0074 0.0512 0.2676
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0129 0.5
Loa Loa (eye worm) hypothetical protein 0.004 0.0159 0.0416
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0141 0.0236
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0054 0.0304 0.0272
Echinococcus multilocularis geminin 0.0203 0.1822 0.1795
Loa Loa (eye worm) hypothetical protein 0.0074 0.0512 0.1336
Schistosoma mansoni lamin 0.0085 0.0625 0.331
Loa Loa (eye worm) hypothetical protein 0.0038 0.0141 0.0368
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0136 0.0598
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0141 0.0159
Schistosoma mansoni hypothetical protein 0.0203 0.1822 1
Brugia malayi Inositol-1 0.0037 0.0136 0.0356
Schistosoma mansoni chromobox protein 0.0082 0.0591 0.312
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0085 0.0625 0.1632
Mycobacterium ulcerans beta-lactamase 0.0038 0.0141 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0054 0.0304 0.0272
Echinococcus multilocularis neuropeptide s receptor 0.1006 1 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0171 0.1499 0.3915
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0221 0.0578
Schistosoma mansoni kinase 0.0057 0.0341 0.1721
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0143 0.0372
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0143 0.0674
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0907 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0075 0.0519 0.0487
Brugia malayi Glycosyl hydrolases family 31 protein 0.0171 0.1499 0.3915
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0907 1
Echinococcus granulosus chromobox protein 1 0.0082 0.0591 0.056
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0143 0.0674
Mycobacterium tuberculosis Conserved protein 0.0038 0.0141 0.0236
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0519 0.5013
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0106 0.0073
Echinococcus multilocularis lamin dm0 0.0085 0.0625 0.0594
Loa Loa (eye worm) hypothetical protein 0.0038 0.0141 0.0368
Echinococcus granulosus ubiquitin specific protease 41 0.0075 0.0519 0.0487
Trypanosoma brucei glucosidase, putative 0.0038 0.0143 0.0179
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0141 0.0159
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0304 0.1516
Schistosoma mansoni lamin 0.0085 0.0625 0.331
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0143 0.011
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.1499 0.1471
Loa Loa (eye worm) beta-lactamase 0.0038 0.0141 0.0368
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0143 0.0674
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0113 0.0907 0.0877
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0519 0.5264
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0136 0.0598
Trichomonas vaginalis chromobox protein, putative 0.005 0.026 0.2102
Brugia malayi MH2 domain containing protein 0.0027 0.0033 0.0087
Loa Loa (eye worm) hypothetical protein 0.0038 0.0141 0.0368
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0141 0.0368
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0136 0.9675
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0141 0.0236
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0519 0.5264
Loa Loa (eye worm) hypothetical protein 0.0034 0.0106 0.0276
Schistosoma mansoni alpha-glucosidase 0.0147 0.1257 0.684
Trichomonas vaginalis chromobox protein, putative 0.005 0.026 0.2102
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0907 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0075 0.0519 0.0487
Onchocerca volvulus 0.0038 0.0141 0.115
Echinococcus multilocularis ubiquitin specific protease 41 0.0075 0.0519 0.0487
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0143 0.011
Schistosoma mansoni hypothetical protein 0.0034 0.0106 0.0405
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0075 0.0519 0.1355
Echinococcus multilocularis chromobox protein 1 0.0082 0.0591 0.056
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0136 0.1503
Brugia malayi beta-lactamase family protein 0.0038 0.0141 0.0368
Echinococcus granulosus lamin 0.0085 0.0625 0.0594
Brugia malayi follicle stimulating hormone receptor 0.024 0.2196 0.5733
Loa Loa (eye worm) hypothetical protein 0.0144 0.1225 0.3199
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0242 0.2218 0.3707
Echinococcus granulosus chromobox protein 1 0.0082 0.0591 0.056
Echinococcus multilocularis musashi 0.0085 0.0625 0.0594
Trypanosoma brucei polo-like protein kinase 0.0113 0.0907 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0141 0.0602
Onchocerca volvulus 0.0036 0.0123 0.1003
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0143 0.0674
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0075 0.0519 0.2716
Brugia malayi Augmenter of liver regeneration 0.0037 0.0129 0.0336
Trichomonas vaginalis esterase, putative 0.0038 0.0141 0.0654
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.0862 0.225
Echinococcus granulosus geminin 0.0203 0.1822 0.1795
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0143 0.1571
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0075 0.0519 0.0487
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0106 0.0073
Echinococcus multilocularis GPCR, family 2 0.0034 0.0106 0.0073
Schistosoma mansoni alpha-glucosidase 0.0147 0.1257 0.684
Schistosoma mansoni intermediate filament proteins 0.0085 0.0625 0.331
Schistosoma mansoni chromobox protein 0.0082 0.0591 0.312
Loa Loa (eye worm) MH2 domain-containing protein 0.04 0.383 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0136 0.01
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0141 0.0236
Echinococcus multilocularis neuropeptide receptor A26 0.1006 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0907 0.4888
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0037 0.0129 0.0096
Loa Loa (eye worm) hypothetical protein 0.0041 0.0175 0.0458
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0054 0.0304 0.0794
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0224 0.1668
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0136 0.0598
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0141 0.0654
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0141 0.0236
Schistosoma mansoni hypothetical protein 0.0034 0.0106 0.0405
Loa Loa (eye worm) hypothetical protein 0.0038 0.0141 0.0368
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0141 0.0654
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0054 0.0304 0.0272
Onchocerca volvulus 0.0085 0.0625 0.5103
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0054 0.0304 0.0272
Brugia malayi Intermediate filament tail domain containing protein 0.0085 0.0625 0.1632
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0037 0.0129 0.0096
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0907 1
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0136 0.0104
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0143 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.1499 0.1471
Brugia malayi beta-lactamase family protein 0.0038 0.0141 0.0368
Loa Loa (eye worm) transcription factor SMAD2 0.04 0.383 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0143 0.0674

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 3 uM Inhibition of Pseudomonas aeruginosa LasB by fluorimetric assay in buffer of pH 7.2 ChEMBL. 19773163

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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