TDR Targets

Basic information

Technical information

TDR Targets ID: 1151186
Name: 5-chloro-6-[2-(hydroxymethyl)piperidin-1-yl]- 1H-pyrimidine-2,4-dione
MW: 259.689 | Formula: C10H14ClN3O3
H donors: 3 H acceptors: 5 LogP: 1.47 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: OCC1CCCCN1c1nc(O)nc(c1Cl)O
InChi: 1S/C10H14ClN3O3/c11-7-8(12-10(17)13-9(7)16)14-4-2-1-3-6(14)5-15/h6,15H,1-5H2,(H2,12,13,16,17)
InChiKey: IGALYJIIRQUAQH-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

5-chloro-6-[2-(hydroxymethyl)-1-piperidyl]-1H-pyrimidine-2,4-dione
5-chloro-6-[2-(hydroxymethyl)-1-piperidinyl]-1H-pyrimidine-2,4-dione
5-chloro-6-(2-methylol-1-piperidyl)uracil

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Toxoplasma gondii	histone lysine methyltransferase SET1	0.011	0.0304	0.0417
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.003	0.0042	0.0042
Brugia malayi	CXXC zinc finger family protein	0.0057	0.0131	0.0131
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0094	0.0253	0.0253
Echinococcus granulosus	microtubule associated protein 2	0.1501	0.4897	0.4897
Echinococcus multilocularis	TGF beta signal transducer SmadC	0.0026	0.0028	0.0028
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0042	0.0042
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0094	0.0253	0.0253
Plasmodium vivax	farnesyltransferase beta subunit, putative	0.0907	0.2936	0.2936
Echinococcus multilocularis	geranylgeranyl transferase type I beta subunit	0.0549	0.1752	0.1752
Echinococcus granulosus	dnaJ subfamily B	0.0816	0.2634	0.2634
Trypanosoma cruzi	protein farnesyltransferase, putative	0.0907	0.2936	1
Brugia malayi	Prenyltransferase and squalene oxidase repeat family protein	0.0549	0.1752	0.1752
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0019	0.0004	0.0004
Mycobacterium tuberculosis	Halimadienyl diphosphate synthase	0.0377	0.1187	0.2376
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0042	0.0042
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0065	0.0158	0.0158
Plasmodium falciparum	protein farnesyltransferase subunit alpha	0.3047	1	1
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0031	0.0031
Toxoplasma gondii	prenyltransferase and squalene oxidase repeat-containing protein	0.0281	0.0869	0.1193
Schistosoma mansoni	hypothetical protein	0.0065	0.0158	0.0158
Plasmodium vivax	prenyltransferase alpha subunit, putative	0.3047	1	1
Echinococcus granulosus	cpg binding protein	0.0061	0.0142	0.0142
Echinococcus granulosus	thymidine phosphorylase	0.1531	0.4995	0.4995
Trypanosoma cruzi	protein farnesyltransferase alpha subunit, putative	0.0822	0.2655	0.9045
Trypanosoma cruzi	protein farnesyltransferase alpha subunit, putative	0.0822	0.2655	0.9045
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.003	0.0042	0.0058
Schistosoma mansoni	TGF-beta signal transducer Smad2	0.0026	0.0028	0.0028
Echinococcus multilocularis	lamin dm0	0.0056	0.0126	0.0126
Loa Loa (eye worm)	prenyltransferase and squalene oxidase repeat family protein	0.0907	0.2936	0.2936
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0094	0.0253	0.0253
Onchocerca volvulus		0.0108	0.0297	0.0977
Echinococcus multilocularis	thymidine phosphorylase	0.1531	0.4995	0.4995
Plasmodium falciparum	geranylgeranyl transferase type-2 subunit alpha, putative	0.0822	0.2655	0.2655
Brugia malayi	MH1 domain containing protein	0.0026	0.0028	0.0028
Trichomonas vaginalis	geranylgeranyl transferase type beta subunit, putative	0.0907	0.2936	0.2399
Schistosoma mansoni	hypothetical protein	0.0141	0.0408	0.0408
Leishmania major	protein farnesyltransferase alpha subunit, putative	0.0822	0.2655	0.9045
Brugia malayi	Pre-SET motif family protein	0.003	0.0042	0.0042
Echinococcus multilocularis	dnaJ subfamily B	0.0816	0.2634	0.2634
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0056	0.0126	0.0126
Echinococcus multilocularis	protein prenyltransferase alpha subunit	0.0822	0.2655	0.2655
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0057	0.0131	0.0131
Echinococcus multilocularis	Smad4	0.0026	0.0028	0.0028
Echinococcus multilocularis	mothers against decapentaplegic 5	0.0026	0.0028	0.0028
Schistosoma mansoni	protein farnesyltransferase subunit beta	0.0907	0.2936	0.2936
Brugia malayi	MH2 domain containing protein	0.0382	0.1203	0.1203
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.003	0.0042	0.0042
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0094	0.0253	0.0253
Schistosoma mansoni	lamin	0.0056	0.0126	0.0126
Entamoeba histolytica	Rab geranylgeranyltransferase alpha subunit, putative	0.0822	0.2655	0.1956
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0094	0.0253	0.0253
Brugia malayi	MH1 domain containing protein	0.0026	0.0028	0.0028
Entamoeba histolytica	geranylgeranyl transferase beta subunit	0.0549	0.1752	0.0967
Trichomonas vaginalis	protein farnesyltransferase alpha subunit, putative	0.0822	0.2655	0.2098
Trypanosoma cruzi	Protein prenyltransferase alpha subunit repeat, putative	0.0822	0.2655	0.9045
Mycobacterium tuberculosis	Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase)	0.1531	0.4995	1
Plasmodium falciparum	protein farnesyltransferase subunit beta	0.0907	0.2936	0.2936
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0028	0.0028
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0094	0.0253	0.0253
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0065	0.0158	0.0158
Trypanosoma brucei	protein farnesyltransferase alpha subunit, putative	0.0822	0.2655	0.9045
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0065	0.0158	0.0158
Loa Loa (eye worm)	prenyltransferase alpha subunit repeat containing protein	0.0822	0.2655	0.2655
Schistosoma mansoni	microtubule-associated protein tau	0.1501	0.4897	0.4897
Trichomonas vaginalis	protein farnesyltransferase beta subunit, putative	0.0281	0.0869	0.0176
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0094	0.0253	0.0253
Echinococcus granulosus	GPCR family 2	0.0065	0.0158	0.0158
Trichomonas vaginalis	geranylgeranyl transferase type II beta subunit, putative	0.0907	0.2936	0.2399
Plasmodium vivax	geranylgeranyltransferase, putative	0.0281	0.0869	0.0869
Plasmodium falciparum	geranylgeranyl transferase type2 beta subunit, putative	0.0281	0.0869	0.0869
Plasmodium falciparum	geranylgeranyltransferase, putative	0.0281	0.0869	0.0869
Plasmodium vivax	conserved Plasmodium protein, unknown function	0.0626	0.2008	0.2008
Brugia malayi	Prenyltransferase and squalene oxidase repeat family protein	0.0907	0.2936	0.2936
Loa Loa (eye worm)	transcription factor SMAD2	0.0382	0.1203	0.1203
Loa Loa (eye worm)	hypothetical protein	0.0207	0.0624	0.0624
Brugia malayi	MH2 domain containing protein	0.0026	0.0028	0.0028
Mycobacterium ulcerans	thymidine phosphorylase	0.1531	0.4995	1
Echinococcus granulosus	Smad4	0.0026	0.0028	0.0028
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.003	0.0041	0.0041
Echinococcus granulosus	TGF beta signal transducer SmadC	0.0026	0.0028	0.0028
Onchocerca volvulus		0.0231	0.0706	0.2539
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0207	0.0624	0.0624
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0065	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0108	0.0297	0.0297
Leishmania major	geranylgeranyltransferase, putative	0.0281	0.0869	0.2962
Trypanosoma cruzi	hypothetical protein, conserved	0.0281	0.0869	0.2962
Loa Loa (eye worm)	hypothetical protein	0.0141	0.0408	0.0408
Trichomonas vaginalis	protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative	0.3047	1	1
Echinococcus granulosus	mothers against decapentaplegic 5	0.0026	0.0028	0.0028
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0123	0.0123
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0065	0.0158	0.0158
Loa Loa (eye worm)	histone methyltransferase	0.0019	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0158	0.0158
Echinococcus granulosus	cytoplasmic intermediate filament protein	0.0027	0.0031	0.0031
Loa Loa (eye worm)	MH2 domain-containing protein	0.0382	0.1203	0.1203
Brugia malayi	Intermediate filament tail domain containing protein	0.0056	0.0126	0.0126
Leishmania major	farnesyltransferase beta subunit	0.0907	0.2936	1
Trypanosoma cruzi	geranylgeranyl transferase type II beta subunit, putative	0.0281	0.0869	0.2962
Schistosoma mansoni	smad1 5 8 and	0.0026	0.0028	0.0028
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0028	0.0034	0.0034
Trypanosoma cruzi	hypothetical protein, conserved	0.0822	0.2655	0.9045
Echinococcus granulosus	protein prenyltransferase alpha subunit	0.0822	0.2655	0.2655
Loa Loa (eye worm)	Smad1	0.0026	0.0028	0.0028
Echinococcus multilocularis	smad	0.0026	0.0028	0.0028
Echinococcus multilocularis	GPCR, family 2	0.0065	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0281	0.0869	0.0869
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0207	0.0624	0.0624
Leishmania major	lanosterol synthase, putative	0.0096	0.0259	0.0883
Plasmodium vivax	geranylgeranyl transferase type2 beta subunit, putative	0.0281	0.0869	0.0869
Toxoplasma gondii	hypothetical protein	0.0822	0.2655	0.3644
Echinococcus granulosus	protein farnesyltransferase subunit beta	0.0907	0.2936	0.2936
Trypanosoma cruzi	protein farnesyltransferase, putative	0.0907	0.2936	1
Echinococcus multilocularis	musashi	0.0056	0.0126	0.0126
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0019	0.0004	0.0004
Brugia malayi	cytoplasmic intermediate filament protein	0.003	0.0041	0.0041
Trypanosoma cruzi	lanosterol synthase, putative	0.0377	0.1187	0.4042
Onchocerca volvulus		0.0056	0.0126	0.0324
Trypanosoma brucei	Protein prenyltransferase alpha subunit repeat, putative	0.0822	0.2655	0.9045
Trypanosoma brucei	protein farnesyltransferase beta subunit	0.0907	0.2936	1
Loa Loa (eye worm)	MH2 domain-containing protein	0.0026	0.0028	0.0028
Schistosoma mansoni	geranylgeranyl transferase type I beta subunit	0.0549	0.1752	0.1752
Toxoplasma gondii	hypothetical protein	0.2225	0.7287	1
Trichomonas vaginalis	type I geranylgeranyltransferase beta subunit, putative	0.0907	0.2936	0.2399
Giardia lamblia	Prenyltransferase	0.0907	0.2936	0.2263
Echinococcus multilocularis	cpg binding protein	0.0061	0.0142	0.0142
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0028	0.0028
Loa Loa (eye worm)	prenyltransferase alpha subunit repeat containing protein	0.3047	1	1
Schistosoma mansoni	hypothetical protein	0.0065	0.0158	0.0158
Schistosoma mansoni	intermediate filament proteins	0.0056	0.0126	0.0126
Loa Loa (eye worm)	MH1 domain-containing protein	0.0026	0.0028	0.0028
Echinococcus granulosus	lamin dm0	0.0056	0.0126	0.0126
Schistosoma mansoni	cpg binding protein	0.0057	0.0131	0.0131
Echinococcus granulosus	intermediate filament protein	0.0056	0.0126	0.0126
Brugia malayi	Probable protein farnesyltransferase beta subunit, putative	0.0281	0.0869	0.0869
Schistosoma mansoni	cpg binding protein	0.0061	0.0142	0.0142
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0207	0.0624	0.0624
Plasmodium vivax	SET domain protein, putative	0.003	0.0042	0.0042
Trypanosoma cruzi	lanosterol synthase, putative	0.0377	0.1187	0.4042
Trypanosoma brucei	geranylgeranyl transferase type II beta subunit, putative	0.0281	0.0869	0.2962
Schistosoma mansoni	protein farnesyltransferase alpha subunit	0.3047	1	1
Echinococcus granulosus	tumor protein p63	0.0735	0.2368	0.2368
Echinococcus granulosus	geranylgeranyl transferase type I beta subunit	0.0549	0.1752	0.1752
Echinococcus granulosus	histone lysine methyltransferase setb	0.003	0.0042	0.0042
Schistosoma mansoni	hypothetical protein	0.0065	0.0158	0.0158
Echinococcus granulosus	geranylgeranyl transferase type 2 subunit alpha	0.0822	0.2655	0.2655
Trichomonas vaginalis	geranylgeranyl transferase type II beta subunit, putative	0.0907	0.2936	0.2399
Trichomonas vaginalis	geranylgeranyl transferase type I beta subunit, putative	0.0549	0.1752	0.1126
Trypanosoma brucei	hypothetical protein, conserved	0.0822	0.2655	0.9045
Trichomonas vaginalis	protein farnesyltransferase alpha subunit, putative	0.3047	1	1
Giardia lamblia	Rab geranylgeranyltransferase	0.3047	1	1
Echinococcus multilocularis	geranylgeranyl transferase type 2 subunit alpha	0.0822	0.2655	0.2655
Schistosoma mansoni	hypothetical protein	0.0065	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0281	0.0869	0.0869
Trichomonas vaginalis	protein farnesyltransferase alpha subunit, putative	0.3047	1	1
Onchocerca volvulus		0.0056	0.0126	0.0324
Brugia malayi	Pre-SET motif family protein	0.0203	0.0613	0.0613
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0094	0.0253	0.0253
Brugia malayi	MH2 domain containing protein	0.0026	0.0028	0.0028
Trichomonas vaginalis	protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative	0.2225	0.7287	0.7081
Schistosoma mansoni	hypothetical protein	0.0816	0.2634	0.2634
Schistosoma mansoni	cpg binding protein	0.0061	0.0142	0.0142
Trypanosoma cruzi	hypothetical protein, conserved	0.0281	0.0869	0.2962
Toxoplasma gondii	Rab geranylgeranyl transferase type II beta subunit, putative	0.0281	0.0869	0.1193
Echinococcus multilocularis	lamin	0.0056	0.0126	0.0126
Giardia lamblia	Rab geranylgeranyltransferase	0.0822	0.2655	0.1956
Echinococcus granulosus	protein farnesyltransferase alpha subunit	0.3047	1	1
Brugia malayi	F/Y-rich N-terminus family protein	0.0019	0.0003	0.0003
Echinococcus multilocularis	Rab geranylgeranyltransferase, beta subunit	0.0281	0.0869	0.0869
Brugia malayi	intermediate filament protein	0.0056	0.0126	0.0126
Brugia malayi	Latrophilin receptor protein 2	0.0065	0.0158	0.0158
Schistosoma mansoni	smad1 5 8 and	0.0026	0.0028	0.0028
Schistosoma mansoni	Smad4	0.0026	0.0028	0.0028
Loa Loa (eye worm)	hypothetical protein	0.3047	1	1
Schistosoma mansoni	geranylgeranyl transferase type I beta subunit	0.0549	0.1752	0.1752
Echinococcus multilocularis	tumor protein p63	0.0735	0.2368	0.2368
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0123	0.0347	0.0347
Plasmodium vivax	protein prenyltransferase alpha subunit, putative	0.0822	0.2655	0.2655
Schistosoma mansoni	smad	0.0026	0.0028	0.0028
Mycobacterium leprae	Probable anthranilate phosphoribosyltransferase TrpD	0.0432	0.1368	0.5
Brugia malayi	Protein prenyltransferase alpha subunit repeat containing protein	0.0822	0.2655	0.2655
Loa Loa (eye worm)	hypothetical protein	0.003	0.0042	0.0042
Schistosoma mansoni	smad1 5 8 and	0.0026	0.0028	0.0028
Loa Loa (eye worm)	intermediate filament protein	0.0056	0.0126	0.0126
Trypanosoma brucei	Protein prenyltransferase alpha subunit repeat, putative	0.0822	0.2655	0.9045
Trichomonas vaginalis	geranylgeranyl transferase type I beta subunit, putative	0.0907	0.2936	0.2399
Echinococcus multilocularis	protein farnesyltransferase subunit beta	0.0907	0.2936	0.2936
Brugia malayi	latrophilin 2 splice variant baaae	0.0141	0.0408	0.0408
Loa Loa (eye worm)	prenyltransferase and squalene oxidase repeat family protein	0.0549	0.1752	0.1752
Brugia malayi	Smad1	0.0026	0.0028	0.0028
Entamoeba histolytica	protein farnesyltransferase beta subunit, putative	0.0907	0.2936	0.2263
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0822	0.2655	0.2655
Trypanosoma brucei	lanosterol synthase	0.0377	0.1187	0.4042
Echinococcus granulosus	lamin	0.0056	0.0126	0.0126
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0042	0.0042
Mycobacterium tuberculosis	Probable anthranilate phosphoribosyltransferase TrpD	0.0432	0.1368	0.2739
Schistosoma mansoni	cellular tumor antigen P53	0.0108	0.0297	0.0297
Schistosoma mansoni	lamin	0.0056	0.0126	0.0126
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0065	0.0158	0.0158
Onchocerca volvulus		0.0057	0.0131	0.0341
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0094	0.0253	0.0253
Trichomonas vaginalis	protein farnesyltransferase beta subunit, putative	0.0281	0.0869	0.0176
Toxoplasma gondii	prenyltransferase and squalene oxidase repeat-containing protein	0.0907	0.2936	0.4029
Echinococcus multilocularis	cytoplasmic intermediate filament protein	0.0027	0.0031	0.0031
Trypanosoma cruzi	hypothetical protein, conserved	0.0822	0.2655	0.9045
Onchocerca volvulus		0.0822	0.2655	1
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0203	0.0613	0.0613
Entamoeba histolytica	protein farnesyltransferase alpha subunit, putative	0.3047	1	1
Echinococcus multilocularis	microtubule associated protein 2	0.1501	0.4897	0.4897
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.003	0.0042	0.0042
Echinococcus granulosus	smad	0.0026	0.0028	0.0028
Schistosoma mansoni	geranylgeranyl transferase type II beta subunit	0.0281	0.0869	0.0869
Echinococcus multilocularis	protein farnesyltransferase alpha subunit	0.3047	1	1
Trichomonas vaginalis	geranylgeranyl transferase type II beta subunit, putative	0.0907	0.2936	0.2399
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0126	0.0126

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL1189378

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1151186