Detailed information for compound 1172417

Basic information

Technical information
  • TDR Targets ID: 1172417
  • Name: 1-(2-pyridin-1-ium-1-ylethyl)pyridin-1-ium
  • MW: 186.253 | Formula: C12H14N2++
  • H donors: 0 H acceptors: 0 LogP: 1.61 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1cc[n+](cc1)CC[n+]1ccccc1
  • InChi: 1S/C12H14N2/c1-3-7-13(8-4-1)11-12-14-9-5-2-6-10-14/h1-10H,11-12H2/q+2
  • InChiKey: AQXSSJVLMRLLQD-UHFFFAOYSA-N  

Network

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Synonyms

  • 1-[2-(1-pyridin-1-iumyl)ethyl]pyridin-1-ium
  • ZINC00395045
  • ALD-N036746

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0112 0.0112
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.2953 0.2953
Schistosoma mansoni ferritin light chain 0.0009 0.0021 0.0021
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0071 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0455 0.0455
Brugia malayi ecdysone receptor 0.001 0.0071 0.0071
Echinococcus granulosus Niemann Pick C1 protein 0.0124 0.3957 0.3957
Brugia malayi MH2 domain containing protein 0.0117 0.3721 0.3721
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0455 0.0455
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0071 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0455 0.0455
Brugia malayi Nuclear hormone receptor E75 0.001 0.0071 0.0071
Schistosoma mansoni ferritin 0.0009 0.0021 0.0021
Echinococcus granulosus expressed protein 0.0009 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.0021 0.0455 0.0455
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0455 0.0455
Entamoeba histolytica hypothetical protein 0.0038 0.1021 0.5
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0455 0.0455
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0455 0.0455
Brugia malayi nuclear receptor RXR 0.0011 0.0112 0.0112
Entamoeba histolytica hypothetical protein 0.0038 0.1021 0.5
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0455 0.0455
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.0021 0.0455 0.0455
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0047 0.0047
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.019 0.6214 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0455 0.0455
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0047 0.0047
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0071 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0455 0.0455
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0112 0.0112
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0455 0.0455
Echinococcus multilocularis sterol regulatory element binding protein 0.0124 0.3957 0.3957
Echinococcus multilocularis Niemann Pick C1 protein 0.0124 0.3957 0.3957
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0112 0.0112
Brugia malayi nuclear hormone receptor 0.0021 0.0455 0.0455
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0047 0.0047
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0071 0.0071
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0455 0.0455
Brugia malayi hypothetical protein 0.0011 0.0112 0.0112
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.1021 0.1021
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0455 0.0455
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0009 0.0021 0.5
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0455 0.0661
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0455 0.0455
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0047 0.0047
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.2953 0.2953
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0455 0.0455
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0047 0.0047
Brugia malayi tailless protein 0.001 0.0071 0.0071
Brugia malayi nuclear hormone receptor 0.001 0.0071 0.0071
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0071 0.0071
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.2953 0.2953
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0071 0.0071
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0455 0.0455
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.0047 0.0047
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.03 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0009 0.0047 0.0047
Brugia malayi nuclear receptor RXR 0.001 0.0071 0.0071
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0047 0.0047
Treponema pallidum bacterioferrin (TpF1) 0.0009 0.0021 0.5
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.0124 0.3957 0.3957
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.03 1 0.5
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0071 0.0071
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0455 0.0455
Brugia malayi DIX domain containing protein 0.0009 0.0047 0.0047
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0071 0.0071
Schistosoma mansoni apoferritin-2 0.0009 0.0021 0.0021
Schistosoma mansoni dep domain containing protein 0.0009 0.0047 0.0047
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0071 0.0071
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0071 0.0038
Toxoplasma gondii hypothetical protein 0.0009 0.0047 0.5
Loa Loa (eye worm) DIX domain-containing protein 0.0009 0.0047 0.0047
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0009 0.0047 0.0047
Schistosoma mansoni nuclear receptor 0.001 0.0071 0.0071
Brugia malayi hypothetical protein 0.001 0.0071 0.0071
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0455 0.0455
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0112 0.0112
Echinococcus granulosus sterol regulatory element binding protein 0.0124 0.3957 0.3957
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0455 0.0455
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0021 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0009 0.0047 0.0047
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0047 0.0047
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.1463 0.1463
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0455 0.0455
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0009 0.0021 0.5
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0047 0.0047
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0455 0.0455
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0455 0.0455
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0071 0.0071
Loa Loa (eye worm) DR-78 0.001 0.0071 0.0071
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.2953 0.2953
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0047 0.0047
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.03 1 1
Loa Loa (eye worm) hypothetical protein 0.0249 0.8236 0.8236
Echinococcus multilocularis protein dispatched 1 0.0124 0.3957 0.3957
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0455 0.0455
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0047 0.0047
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.3721 0.3721
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0021 0.0455 0.0455
Brugia malayi steroid hormone receptor 0.0021 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0455 0.0455
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0455 0.0455
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0047 0.0047
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0455 0.0455
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0455 0.0455
Schistosoma mansoni zinc finger protein 0.001 0.0071 0.0071
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Brugia malayi hypothetical protein 0.0249 0.8236 0.8236
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.3721 0.3721
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.0021 0.5
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0047 0.0047
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.1021 0.1021
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0455 0.0455
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0455 0.0455
Echinococcus multilocularis ferritin 0.0009 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0009 0.0047 0.0047
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0112 0.0112
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0124 0.3957 0.3957
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.2953 0.2953
Brugia malayi nuclear receptor NHR-88 0.001 0.0071 0.0071
Entamoeba histolytica hypothetical protein 0.0038 0.1021 0.5
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.03 1 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0455 0.0455
Schistosoma mansoni nuclear hormone receptor 0.001 0.0071 0.0071
Schistosoma mansoni ferritin 0.0009 0.0021 0.0021
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.03 1 0.5
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Schistosoma mansoni nuclear receptor 0.001 0.0071 0.0071
Brugia malayi conserved hypotetical protein 0.001 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0021 0.0455 0.0455
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Schistosoma mansoni nuclear hormone receptor 0.001 0.0071 0.0071
Brugia malayi hypothetical protein 0.0011 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0038 0.1021 0.1021
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0455 0.0455
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0455 0.0455
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0021 0.0455 0.0455
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0141 0.4547 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0455 0.0455
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0112 0.0112
Schistosoma mansoni patched 1 0.0124 0.3957 0.3957
Brugia malayi hypothetical protein 0.0009 0.0047 0.0047
Brugia malayi N-terminal motif family protein 0.019 0.6214 0.6214
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.0021 0.5
Brugia malayi Nuclear hormone receptor E75 0.001 0.0071 0.0071
Schistosoma mansoni ferritin 0.0009 0.0021 0.0021
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0071 0.0071
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0047 0.0047
Schistosoma mansoni coup transcription factor 0.0021 0.0455 0.0455
Onchocerca volvulus 0.0021 0.0455 0.0661
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.03 1 0.5
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0455 0.0455
Schistosoma mansoni dishevelled 0.0009 0.0047 0.0047
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0455 0.0455
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0455 0.0455
Onchocerca volvulus 0.0051 0.1463 0.2297
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0455 0.0455
Echinococcus multilocularis survival motor neuron protein 1 0.0249 0.8236 0.8236
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0141 0.4547 1
Onchocerca volvulus 0.001 0.0071 0.0038
Brugia malayi CHE-14 protein 0.0124 0.3957 0.3957
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.03 1 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0124 0.3957 0.3957
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0071 0.0071
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0455 0.0455
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0455 0.0455
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0455 0.0455
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.2953 0.2953
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0455 0.0455
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.1021 0.1021
Loa Loa (eye worm) hypothetical protein 0.019 0.6214 0.6214
Schistosoma mansoni hypothetical protein 0.0051 0.1463 0.1463
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0071 0.0071
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0455 0.0661
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.2953 0.2953
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0455 0.0455
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0071 0.0071
Brugia malayi hypothetical protein 0.0009 0.0047 0.0047
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0455 0.0455
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0455 0.0661
Schistosoma mansoni apoferritin-2 0.0009 0.0021 0.0021
Echinococcus multilocularis expressed protein 0.0009 0.0021 0.0021
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Onchocerca volvulus 0.001 0.0071 0.0038
Brugia malayi ecdysteroid receptor 0.0021 0.0455 0.0455
Brugia malayi nuclear receptor NHR-67 0.001 0.0071 0.0071
Echinococcus granulosus Protein patched homolog 1 0.0124 0.3957 0.3957
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0455 0.0455
Echinococcus granulosus ferritin 0.0009 0.0021 0.0021
Schistosoma mansoni ferritin 0.0009 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0455 0.0455
Echinococcus granulosus survival motor neuron protein 1 0.0249 0.8236 0.8236
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0071 0.0071
Brugia malayi hypothetical protein 0.0038 0.1021 0.1021
Brugia malayi nuclear receptor NHR-88 0.0021 0.0455 0.0455
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0071 0.0071
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0141 0.4547 0.5
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0071 0.0071
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0071 0.0071
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0455 0.0455
Entamoeba histolytica hypothetical protein 0.0038 0.1021 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.2953 0.2953
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0141 0.4547 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.2953 0.2953
Loa Loa (eye worm) hypothetical protein 0.03 1 1
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0047 0.0047
Brugia malayi hypothetical protein 0.001 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.3957 0.8696
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0455 0.0455
Echinococcus multilocularis protein patched 0.0124 0.3957 0.3957
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0455 0.0455
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.03 1 1
Schistosoma mansoni dishevelled 0.0009 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0047 0.0047
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0011 0.0112 0.0112
Schistosoma mansoni survival motor neuron protein 0.0051 0.1463 0.1463
Schistosoma mansoni ferritin light chain 0.0009 0.0021 0.0021
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0071 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0455 0.0455
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.001 0.0071 0.0071

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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