Detailed information for compound 1289969

Basic information

Technical information
  • TDR Targets ID: 1289969
  • Name: MLS000773525
  • MW: 259.218 | Formula: C12H9N3O4
  • H donors: 2 H acceptors: 4 LogP: 0.8 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(nn1)C(=O)Nc1ccc2c(c1)OCO2
  • InChi: 1S/C12H9N3O4/c16-11-4-2-8(14-15-11)12(17)13-7-1-3-9-10(5-7)19-6-18-9/h1-5H,6H2,(H,13,17)(H,15,16)
  • InChiKey: FRWZAXMXHLMKMU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(1,3-benzodioxol-5-yl)-6-oxo-1H-pyridazine-3-carboxamide
  • N-(1,3-benzodioxol-5-yl)-6-keto-1H-pyridazine-3-carboxamide
  • SDCCGMLS-0065757.P001
  • SMR000364230
  • T0513-2699
  • ZINC03263962

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0037 0.0102 0.0967
Brugia malayi isocitrate dehydrogenase 0.0017 0.0022 0.002
Loa Loa (eye worm) nuclear factor I 0.0018 0.0026 0.0031
Toxoplasma gondii ABC1 family protein 0.0037 0.0102 1
Brugia malayi RNA, U transporter 1 0.009 0.0319 0.0654
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0102 0.0902
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0047 0.4589
Brugia malayi MH2 domain containing protein 0.0033 0.0087 0.0159
Brugia malayi Pre-SET motif family protein 0.0213 0.0819 0.1719
Echinococcus granulosus smad 0.0033 0.0087 0.0184
Entamoeba histolytica hypothetical protein 0.0146 0.0547 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0087 0.0184
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0102 0.1083
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0022 0.2114
Plasmodium vivax importin-beta 2, putative 0.0032 0.0081 0.7943
Schistosoma mansoni smad1 5 8 and 0.0033 0.0087 0.0184
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0053 0.5192
Loa Loa (eye worm) hypothetical protein 0.0037 0.0102 0.0191
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0102 1
Schistosoma mansoni hypothetical protein 0.0083 0.029 0.0615
Onchocerca volvulus 0.0037 0.0102 0.0967
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0102 0.0902
Loa Loa (eye worm) hypothetical protein 0.0037 0.0102 0.0191
Schistosoma mansoni smad1 5 8 and 0.0033 0.0087 0.0184
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0047 1
Onchocerca volvulus 0.0031 0.0076 0.0691
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0056 0.06
Loa Loa (eye worm) hypothetical protein 0.1166 0.47 1
Echinococcus granulosus importin subunit beta 1 0.0032 0.0081 0.0172
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0087 0.0184
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0076 0.0162
Brugia malayi Calcitonin receptor-like protein seb-1 0.0262 0.102 0.2146
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.0547 0.0547
Schistosoma mansoni hypothetical protein 0.0339 0.1331 0.2827
Entamoeba histolytica hypothetical protein 0.0146 0.0547 1
Leishmania major hypothetical protein, conserved 0.0037 0.0102 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0056 0.06
Brugia malayi Neuronal symmetry protein 1 0.1168 0.4708 1
Mycobacterium tuberculosis Conserved protein 0.0037 0.0102 0.0902
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0083 0.029 0.029
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0047 0.0074
Entamoeba histolytica hypothetical protein 0.0026 0.0056 0.1029
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0339 0.1331 0.2813
Loa Loa (eye worm) hypothetical protein 0.0262 0.102 0.2149
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0102 0.0586
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0083 0.029 0.029
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0102 0.0902
Echinococcus multilocularis snurportin 1 0.0339 0.1331 0.1331
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0053 0.3903
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.0911 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0353 0.1391 1
Brugia malayi Importin beta-1 subunit 0.0032 0.0081 0.0146
Schistosoma mansoni Smad4 0.0015 0.0012 0.0026
Loa Loa (eye worm) hypothetical protein 0.0037 0.0102 0.0191
Loa Loa (eye worm) hypothetical protein 0.0083 0.029 0.0592
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0081 0.7943
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0053 0.5192
Mycobacterium ulcerans beta-lactamase 0.0037 0.0102 0.5
Echinococcus granulosus snurportin 1 0.0339 0.1331 0.2827
Brugia malayi MH1 domain containing protein 0.0018 0.0026 0.0031
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0047 0.0047
Schistosoma mansoni smad1 5 8 and 0.0033 0.0087 0.0184
Echinococcus granulosus Smad4 0.0033 0.0087 0.0184
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0022 0.2114
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0022 0.0022
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0022 0.0022
Mycobacterium leprae Probable lipase LipE 0.0037 0.0102 0.5
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0262 0.102 0.2149
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0022 0.0022
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0083 0.029 0.0615
Leishmania major hypothetical protein, conserved 0.0025 0.0053 0.3903
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0053 0.6536
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0053 0.6536
Echinococcus multilocularis geminin 0.0344 0.1352 0.1352
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0102 0.0216
Loa Loa (eye worm) MH2 domain-containing protein 0.0487 0.1936 0.4103
Schistosoma mansoni smad 0.0033 0.0087 0.0184
Loa Loa (eye worm) hypothetical protein 0.0032 0.0081 0.0147
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0087 0.0087
Leishmania major importin beta-1 subunit, putative 0.0026 0.0056 0.4345
Echinococcus multilocularis mothers against decapentaplegic 2 0.0015 0.0012 0.0012
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0047 0.3139
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0102 0.0216
Schistosoma mansoni protein kinase 0.1168 0.4708 1
Brugia malayi MH2 domain containing protein 0.0487 0.1936 0.4097
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1168 0.4708 1
Schistosoma mansoni hypothetical protein 0.0083 0.029 0.0615
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1168 0.4708 0.4708
Onchocerca volvulus 0.0037 0.0102 0.0967
Entamoeba histolytica hypothetical protein 0.0146 0.0547 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0262 0.102 0.2146
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0047 0.4589
Loa Loa (eye worm) hypothetical protein 0.0179 0.0682 0.1428
Loa Loa (eye worm) hypothetical protein 0.0037 0.0102 0.0191
Loa Loa (eye worm) hypothetical protein 0.0025 0.0053 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0102 0.0586
Brugia malayi beta-lactamase family protein 0.0037 0.0102 0.0191
Loa Loa (eye worm) hypothetical protein 0.0037 0.0102 0.0191
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0022 0.0046
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0102 0.0902
Schistosoma mansoni protein kinase 0.1168 0.4708 1
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.0547 0.1163
Echinococcus granulosus GPCR family 2 0.0083 0.029 0.0615
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0083 0.029 0.0591
Echinococcus multilocularis mothers against decapentaplegic 6 0.0015 0.0012 0.0012
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0047 0.0074
Entamoeba histolytica Ran family GTPase 0.0023 0.0047 0.0853
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0076 0.7478
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0102 0.1083
Trichomonas vaginalis ran, putative 0.0023 0.0047 0.0497
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0022 0.0022
Schistosoma mansoni Smad4 0.0015 0.0012 0.0026
Loa Loa (eye worm) Smad1 0.0033 0.0087 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0076 0.0162
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0102 0.0102
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0102 0.0191
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0102 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0353 0.1391 1
Schistosoma mansoni ran 0.0023 0.0047 0.0099
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0022 0.2114
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0102 0.0902
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0102 0.5
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0087 0.0184
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0102 0.5
Schistosoma mansoni hypothetical protein 0.0344 0.1352 0.2873
Trichomonas vaginalis set domain proteins, putative 0.0243 0.0939 1
Echinococcus granulosus mothers against decapentaplegic 6 0.0015 0.0012 0.0026
Brugia malayi MH1 domain containing protein 0.0033 0.0087 0.0159
Brugia malayi latrophilin 2 splice variant baaae 0.0179 0.0682 0.1426
Brugia malayi hypothetical protein 0.0146 0.0547 0.114
Mycobacterium ulcerans hypothetical protein 0.0037 0.0102 0.5
Leishmania major GTP-binding protein, putative 0.0023 0.0047 0.3139
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0081 0.7392
Loa Loa (eye worm) hypothetical protein 0.0352 0.1384 0.2926
Schistosoma mansoni ran 0.0023 0.0047 0.0099
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0022 0.2662
Mycobacterium tuberculosis Conserved protein 0.0037 0.0102 0.0902
Brugia malayi MH2 domain containing protein 0.0033 0.0087 0.0159
Plasmodium vivax SET domain protein, putative 0.0031 0.0076 0.7478
Onchocerca volvulus 0.0243 0.0939 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0102 0.1083
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0053 0.0229
Schistosoma mansoni hypothetical protein 0.0083 0.029 0.0615
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0102 0.0902
Schistosoma mansoni Smad4 0.0033 0.0087 0.0184
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0087 0.0159
Schistosoma mansoni hypothetical protein 0.0146 0.0547 0.1163
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0076 0.0162
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0056 0.0254
Brugia malayi Smad1 0.0033 0.0087 0.0159
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0056 0.06
Loa Loa (eye worm) STE/STE11/ASK protein kinase 0.0353 0.1391 0.2941
Plasmodium falciparum importin beta, putative 0.0032 0.0081 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0102 0.0216
Brugia malayi MH1 domain containing protein 0.0018 0.0026 0.0031
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0022 0.002
Brugia malayi MH1 domain containing protein 0.0033 0.0087 0.0159
Brugia malayi beta-lactamase family protein 0.0037 0.0102 0.0191
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0053 0.0229
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0076 0.0162
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0102 0.0191
Loa Loa (eye worm) hypothetical protein 0.0037 0.0102 0.0191
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0076 0.0076
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.0547 0.1163
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0102 0.1083
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0022 0.0046
Echinococcus granulosus mothers against decapentaplegic 2 0.0015 0.0012 0.0026
Trichomonas vaginalis esterase, putative 0.0037 0.0102 0.1083
Echinococcus multilocularis GPCR, family 2 0.0083 0.029 0.029
Schistosoma mansoni hypothetical protein 0.0083 0.029 0.0615
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0076 0.0137
Echinococcus multilocularis smad 0.0033 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.0179 0.0682 0.1448
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0071 0.0152
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0102 0.0902
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0083 0.029 0.0615
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0047 0.0099
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0076 0.0162
Mycobacterium ulcerans lipase LipD 0.0037 0.0102 0.5
Loa Loa (eye worm) transcription factor SMAD2 0.0487 0.1936 0.4103
Echinococcus granulosus geminin 0.0344 0.1352 0.2873
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0102 1
Brugia malayi hypothetical protein 0.0016 0.0017 0.001
Schistosoma mansoni smad 0.0015 0.0012 0.0026
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0213 0.0819 0.1722
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0047 0.0184
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0022 0.002
Echinococcus multilocularis Smad4 0.0033 0.0087 0.0087
Loa Loa (eye worm) latrophilin receptor protein 2 0.0083 0.029 0.0592
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0087 0.0087
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0081 0.7392
Schistosoma mansoni hypothetical protein 0.0344 0.1352 0.2873
Loa Loa (eye worm) beta-lactamase 0.0037 0.0102 0.0191
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0047 0.5778
Brugia malayi Latrophilin receptor protein 2 0.0083 0.029 0.0591
Brugia malayi Pre-SET motif family protein 0.0031 0.0076 0.0136
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0102 0.1083
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0087 0.0159
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0076 0.0076
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0081 0.0081
Schistosoma mansoni importin beta-1 0.0032 0.0081 0.0172
Mycobacterium tuberculosis Conserved protein 0.0037 0.0102 0.0902
Entamoeba histolytica hypothetical protein 0.0146 0.0547 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0047 0.0184
Brugia malayi hypothetical protein 0.0025 0.0053 0.0087
Brugia malayi beta-lactamase 0.0037 0.0102 0.0191

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.3753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.3489 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 21.3313 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) = 89.1251 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 89.1251 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.