Detailed information for compound 1467579

Basic information

Technical information
  • TDR Targets ID: 1467579
  • Name: 2-[(4-methoxyphenyl)methylamino]-N-(3-sulfamo ylphenyl)acetamide
  • MW: 349.405 | Formula: C16H19N3O4S
  • H donors: 3 H acceptors: 3 LogP: 0.73 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)CNCC(=O)Nc1cccc(c1)S(=O)(=O)N
  • InChi: 1S/C16H19N3O4S/c1-23-14-7-5-12(6-8-14)10-18-11-16(20)19-13-3-2-4-15(9-13)24(17,21)22/h2-9,18H,10-11H2,1H3,(H,19,20)(H2,17,21,22)
  • InChiKey: SZIWVIWCUKRPAC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(4-methoxybenzyl)amino]-N-(3-sulfamoylphenyl)acetamide
  • 2-[(4-methoxyphenyl)methylamino]-N-(3-sulfamoylphenyl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0391 0.4234
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0176 0.4876 0.4876
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0837 0.1285
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0515 0.1041
Schistosoma mansoni tar DNA-binding protein 0.0067 0.174 0.174
Loa Loa (eye worm) hypothetical protein 0.0036 0.0837 0.0829
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0391 0.0786
Loa Loa (eye worm) hypothetical protein 0.0097 0.2602 0.2596
Schistosoma mansoni hypothetical protein 0.0011 0.0118 0.0118
Echinococcus granulosus traf and tnf receptor associated protein 0.0007 0.0009 0.0009
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0007 0.0009 0.0009
Leishmania major hypothetical protein, conserved 0.0036 0.0837 0.0829
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0857 0.1743
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0857 0.0857
Echinococcus multilocularis neutral sphingomyelinase 0.0007 0.0009 0.0009
Schistosoma mansoni importin beta-1 0.0028 0.0605 0.0605
Leishmania major importin beta-1 subunit, putative 0.0023 0.0452 0.0444
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0623 0.0615
Entamoeba histolytica Ran family GTPase 0.0021 0.0391 0.2119
Schistosoma mansoni hypothetical protein 0.0031 0.0683 0.0683
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0515 0.0507
Schistosoma mansoni ap endonuclease 0.0037 0.0857 0.0857
Entamoeba histolytica hypothetical protein 0.0023 0.0452 0.2455
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0391 0.0383
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0353 1 1
Schistosoma mansoni tar DNA-binding protein 0.0067 0.174 0.174
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.6458 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0837 0.1285
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0391 0.0391
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0353 1 1
Echinococcus granulosus carbonic anhydrase II 0.0353 1 1
Loa Loa (eye worm) acetyltransferase 0.0144 0.3942 0.3937
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0051 0.0051
Echinococcus multilocularis carbonic anhydrase II 0.0353 1 1
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0605 0.0605
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0007 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0837 0.0829
Schistosoma mansoni hypothetical protein 0.017 0.4703 0.4703
Trypanosoma brucei carbonic anhydrase-like protein 0.0353 1 1
Loa Loa (eye worm) hypothetical protein 0.0166 0.4588 0.4584
Toxoplasma gondii Erv1 / Alr family protein 0.0176 0.4876 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0166 0.4588 0.4584
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0166 0.4588 0.4584
Leishmania major carbonic anhydrase-like protein 0.0353 1 1
Echinococcus multilocularis carbonic anhydrase 0.0166 0.4588 0.4588
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.1814 0.1814
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0515 0.0507
Echinococcus granulosus tar DNA binding protein 0.0067 0.174 0.174
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0683 0.0675
Onchocerca volvulus Sulfhydryl oxidase homolog 0.0028 0.0602 0.7162
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0837 0.0837
Echinococcus multilocularis geminin 0.017 0.4703 0.4703
Schistosoma mansoni hypothetical protein 0.0066 0.1714 0.1714
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0007 0.0009 0.0009
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0166 0.4588 0.4584
Schistosoma mansoni ran 0.0021 0.0391 0.0391
Plasmodium vivax importin-beta 2, putative 0.0028 0.0605 0.1226
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0391 0.0786
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0857 0.1315
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.3942 0.3942
Echinococcus multilocularis muscleblind protein 0.0145 0.3971 0.3971
Loa Loa (eye worm) hypothetical protein 0.0145 0.3971 0.3966
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0007 0.0009 0.0009
Brugia malayi hypothetical protein 0.0025 0.0515 0.0507
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0353 1 1
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0452 0.441
Loa Loa (eye worm) hypothetical protein 0.0036 0.0837 0.0829
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0007 0.0009 0.0009
Brugia malayi Muscleblind-like protein 0.0145 0.3971 0.3966
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0166 0.4588 0.4584
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.3689 0.3689
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0605 0.1226
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0166 0.4588 0.4584
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0176 0.4876 0.4872
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0837 0.1285
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.3942 0.3942
Brugia malayi beta-lactamase 0.0036 0.0837 0.0829
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0051 0.0051
Schistosoma mansoni carbonic anhydrase-related 0.0166 0.4588 0.4588
Brugia malayi quiescin Q6 0.0028 0.0602 0.0594
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0176 0.4876 0.4872
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0837 0.0829
Brugia malayi RNA, U transporter 1 0.008 0.2101 0.2095
Brugia malayi latrophilin 2 splice variant baaae 0.0066 0.1714 0.1707
Schistosoma mansoni tar DNA-binding protein 0.0067 0.174 0.174
Trichomonas vaginalis esterase, putative 0.0036 0.0837 0.8241
Brugia malayi hypothetical protein 0.0016 0.026 0.0251
Loa Loa (eye worm) hypothetical protein 0.0166 0.4588 0.4584
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0007 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.017 0.4703 0.4703
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0452 0.441
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0118 0.0118
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0837 0.8241
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.1466 0.2995
Plasmodium falciparum carbonic anhydrase 0.0166 0.4588 0.9409
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.3689 0.3689
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0515 0.1041
Loa Loa (eye worm) hepatopoietin HPO2 0.0176 0.4876 0.4872
Onchocerca volvulus 0.0029 0.0623 0.7417
Loa Loa (eye worm) hypothetical protein 0.0028 0.0605 0.0597
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0353 1 1
Schistosoma mansoni quiescin q6-related sulfhydryl oxidase 0.0028 0.0602 0.0602
Echinococcus granulosus carbonic anhydrase 0.0166 0.4588 0.4588
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0837 0.5
Plasmodium falciparum importin beta, putative 0.0028 0.0605 0.1226
Schistosoma mansoni hypothetical protein 0.0007 0.0009 0.0009
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.8456 0.8455
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0857 0.9387
Echinococcus granulosus GPCR family 2 0.0031 0.0683 0.0683
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0837 0.1285
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.3689 0.3689
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0857 0.4698
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0391 0.0786
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0683 0.0683
Onchocerca volvulus 0.0036 0.0837 1
Schistosoma mansoni tar DNA-binding protein 0.0067 0.174 0.174
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0166 0.4588 0.4584
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0135 0.3689 0.3683
Loa Loa (eye worm) hypothetical protein 0.0036 0.0837 0.0829
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0837 0.1285
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0605 0.0597
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0391 0.0383
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0515 0.1041
Schistosoma mansoni hypothetical protein 0.0031 0.0683 0.0683
Brugia malayi hypothetical protein 0.007 0.1814 0.1807
Entamoeba histolytica hypothetical protein 0.007 0.1814 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0452 0.0444
Loa Loa (eye worm) RNA binding protein 0.0067 0.174 0.1733
Trypanosoma brucei quiescin sulfhydryl oxidase 0.0028 0.0602 0.0594
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0857 0.0849
Leishmania major hypothetical protein, conserved 0.0025 0.0515 0.0507
Brugia malayi TAR-binding protein 0.0067 0.174 0.1733
Entamoeba histolytica hypothetical protein 0.007 0.1814 1
Loa Loa (eye worm) beta-lactamase 0.0036 0.0837 0.0829
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0837 0.8241
Brugia malayi Erv1 / Alr family protein 0.0028 0.0602 0.0594
Echinococcus granulosus carbonic anhydrase 0.0166 0.4588 0.4588
Entamoeba histolytica hypothetical protein 0.007 0.1814 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0097 0.2602 0.2596
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0176 0.4876 0.4876
Schistosoma mansoni cpg binding protein 0.003 0.067 0.067
Loa Loa (eye worm) hypothetical protein 0.0066 0.1714 0.1707
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0857 0.0857
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0857 1
Brugia malayi CXXC zinc finger family protein 0.0029 0.0623 0.0615
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0515 0.1041
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0353 1 1
Leishmania major hypothetical protein, conserved 0.0176 0.4876 0.4872
Schistosoma mansoni nocturnin 0.0007 0.0009 0.0009
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0176 0.4876 1
Schistosoma mansoni carbonic anhydrase-related 0.0166 0.4588 0.4588
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0857 0.8438
Brugia malayi Importin beta-1 subunit 0.0028 0.0605 0.0597
Schistosoma mansoni cpg binding protein 0.003 0.067 0.067
Schistosoma mansoni hypothetical protein 0.0031 0.0683 0.0683
Schistosoma mansoni carbonic anhydrase-related 0.0166 0.4588 0.4588
Loa Loa (eye worm) Erv1/Alr family protein 0.0028 0.0602 0.0594
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0837 0.0829
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0837 0.1285
Brugia malayi Augmenter of liver regeneration 0.0176 0.4876 0.4872
Loa Loa (eye worm) hypothetical protein 0.0031 0.0683 0.0675
Echinococcus granulosus neutral sphingomyelinase 0.0007 0.0009 0.0009
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.174 0.1733
Schistosoma mansoni ap endonuclease 0.0037 0.0857 0.0857
Toxoplasma gondii Erv1 / Alr family protein 0.0028 0.0602 0.1219
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0007 0.0009 0.0009
Schistosoma mansoni synaptojanin 0.0007 0.0009 0.0009
Schistosoma mansoni cript-related 0.0007 0.0009 0.0009
Schistosoma mansoni synaptojanin 0.0007 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0837 0.0829
Trypanosoma cruzi quiescin sulfhydryl oxidase, putative 0.0028 0.0602 0.0594
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0837 0.8241
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0857 0.0849
Echinococcus multilocularis muscleblind protein 1 0.0145 0.3971 0.3971
Brugia malayi beta-lactamase family protein 0.0036 0.0837 0.0829
Schistosoma mansoni transcription factor LCR-F1 0.007 0.1814 0.1814
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.1814 0.1814
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0391 0.0383
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0683 0.0683
Loa Loa (eye worm) TAR-binding protein 0.0067 0.174 0.1733
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.3942 0.3937
Toxoplasma gondii hypothetical protein 0.0166 0.4588 0.9409
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.3689 0.3689
Schistosoma mansoni hypothetical protein 0.0031 0.0683 0.0683
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0912 0.5004
Loa Loa (eye worm) quiescin Q6 0.0028 0.0602 0.0594
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0912 1
Schistosoma mansoni hypothetical protein 0.007 0.1814 0.1814
Schistosoma mansoni carbon catabolite repressor protein 0.0007 0.0009 0.0009
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0857 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.3689 0.3689
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0515 0.0507
Brugia malayi Calcitonin receptor-like protein seb-1 0.0097 0.2602 0.2596
Loa Loa (eye worm) hypothetical protein 0.0025 0.0515 0.0507
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0857 0.0849
Mycobacterium tuberculosis Conserved protein 0.0036 0.0837 0.1285
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0602 0.1219
Schistosoma mansoni cpg binding protein 0.0029 0.0623 0.0623
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0857 0.5
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.3826 0.3826
Loa Loa (eye worm) hypothetical protein 0.0028 0.0602 0.0594
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0857 0.0849
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0857 0.1743
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0837 0.8241
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0837 0.0829
Echinococcus multilocularis synaptojanin 1 0.0007 0.0009 0.0009
Echinococcus multilocularis traf and tnf receptor associated protein 0.0007 0.0009 0.0009
Trichomonas vaginalis ran, putative 0.0021 0.0391 0.3806
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0837 0.0837
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0353 1 1
Echinococcus granulosus sulfhydryl oxidase 1 0.0028 0.0602 0.0602
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0047 0.0039
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0176 0.4876 0.4872
Echinococcus granulosus importin subunit beta 1 0.0028 0.0605 0.0605
Echinococcus granulosus synaptojanin 1 0.0007 0.0009 0.0009
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0176 0.4876 1
Echinococcus multilocularis carbonic anhydrase 0.0166 0.4588 0.4588
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0135 0.3689 0.3683
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0837 0.1285
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.3689 0.3689
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0683 0.0683
Onchocerca volvulus 0.0036 0.0837 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0837 0.0829
Onchocerca volvulus Sulfhydryl oxidase homolog 0.0028 0.0602 0.7162
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0605 0.0597
Entamoeba histolytica hypothetical protein 0.007 0.1814 1
Echinococcus granulosus cpg binding protein 0.003 0.067 0.067
Echinococcus granulosus carbonic anhydrase 0.0166 0.4588 0.4588
Echinococcus multilocularis sulfhydryl oxidase 1 0.0028 0.0602 0.0602
Onchocerca volvulus Sulfhydryl oxidase homolog 0.0028 0.0602 0.7162
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.174 0.1733
Echinococcus multilocularis tar DNA binding protein 0.0067 0.174 0.174
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0051 0.0042
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0837 0.8241
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.1014 1
Schistosoma mansoni carbonic anhydrase 0.0166 0.4588 0.4588
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.1014 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0837 0.0837
Loa Loa (eye worm) hypothetical protein 0.0028 0.0602 0.0594
Toxoplasma gondii Erv1 / Alr family protein 0.0176 0.4876 1
Echinococcus multilocularis carbonic anhydrase 0.0166 0.4588 0.4588
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0837 0.0837
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0391 0.0383
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.3689 0.3689
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0857 0.8438
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0028 0.0602 0.1219
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0097 0.2602 0.2596
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0391 0.0383
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.1553 0.1553
Toxoplasma gondii ABC1 family protein 0.0036 0.0837 0.1702
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0118 0.0118
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0837 0.1285
Leishmania major GTP-binding protein, putative 0.0021 0.0391 0.0383
Trypanosoma cruzi quiescin sulfhydryl oxidase, putative 0.0028 0.0602 0.0594
Brugia malayi beta-lactamase family protein 0.0036 0.0837 0.0829
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0683 0.0675
Echinococcus granulosus muscleblind protein 0.0145 0.3971 0.3971
Echinococcus multilocularis deoxyribonuclease 1 2 0.0007 0.0009 0.0009
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.1014 0.1014
Echinococcus multilocularis GPCR, family 2 0.0031 0.0683 0.0683
Mycobacterium leprae Probable lipase LipE 0.0036 0.0837 0.5
Echinococcus multilocularis cpg binding protein 0.003 0.067 0.067
Schistosoma mansoni hypothetical protein 0.03 0.8456 0.8456
Loa Loa (eye worm) hypothetical protein 0.0145 0.3971 0.3966
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0391 0.0391
Echinococcus granulosus geminin 0.017 0.4703 0.4703
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.1014 0.2065
Schistosoma mansoni tar DNA-binding protein 0.0067 0.174 0.174
Echinococcus granulosus snurportin 1 0.03 0.8456 0.8456
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0176 0.4876 0.4872
Brugia malayi RNA binding protein 0.0067 0.174 0.1733
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0683 0.0683
Toxoplasma gondii exonuclease III APE 0.0037 0.0857 0.1743
Echinococcus multilocularis snurportin 1 0.03 0.8456 0.8456
Onchocerca volvulus 0.0036 0.0837 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0837 0.1285
Schistosoma mansoni hypothetical protein 0.0166 0.4588 0.4588
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.1014 0.2065
Schistosoma mansoni neutral sphingomyelinase 0.0007 0.0009 0.0009
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0857 0.0849
Loa Loa (eye worm) hypothetical protein 0.0166 0.4588 0.4584
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.1014 0.2065
Loa Loa (eye worm) hypothetical protein 0.0036 0.0837 0.0829
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0837 0.1702
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0912 0.1857
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0683 0.0675
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0857 0.0849
Loa Loa (eye worm) carbonic anhydrase 3 0.0353 1 1
Schistosoma mansoni ran 0.0021 0.0391 0.0391
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0452 0.441
Loa Loa (eye worm) hypothetical protein 0.0036 0.0837 0.0829

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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