Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | lysine--tRNA ligase, putative | 0.0093 | 0.0297 | 0.0249 |
Plasmodium falciparum | calcium-dependent protein kinase 2 | 0.0128 | 0.0448 | 0.0307 |
Schistosoma mansoni | glucose transporter | 0.0059 | 0.0146 | 0.0098 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Trypanosoma cruzi | hexose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0905 | 0.3837 | 1 |
Mycobacterium leprae | Possible lysyl-tRNA synthetase 2 LysX | 0.0093 | 0.0297 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0437 | 0.2549 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0905 | 0.3837 | 1 |
Leishmania major | prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative | 0.0146 | 0.0527 | 0.0481 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0048 | 0.0282 |
Onchocerca volvulus | 0.005 | 0.0108 | 0.6068 | |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0418 | 0.1713 | 0.4463 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0905 | 0.3837 | 1 |
Brugia malayi | Sugar transporter family protein | 0.0059 | 0.0146 | 0.0134 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0048 | 0.0036 |
Echinococcus granulosus | solute carrier family 22 | 0.0059 | 0.0146 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Leishmania major | myo-inositol/proton symporter (MIT) | 0.0059 | 0.0146 | 0.0098 |
Schistosoma mansoni | lysyl-tRNA synthetase | 0.0093 | 0.0297 | 0.0249 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0055 | 0.0129 | 0.0336 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.2319 | 1 | 1 |
Toxoplasma gondii | sugar transporter ST2 | 0.0059 | 0.0146 | 0.0098 |
Trichomonas vaginalis | conserved hypothetical protein | 0.013 | 0.0455 | 0.1073 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type | 0.0128 | 0.0448 | 0.1167 |
Trypanosoma brucei | glucose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Brugia malayi | Major Facilitator Superfamily protein | 0.0059 | 0.0146 | 0.0134 |
Trichomonas vaginalis | sugar transporter, putative | 0.013 | 0.0455 | 0.1073 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0048 | 0.0282 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.2319 | 1 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.01 | 0.0052 |
Plasmodium vivax | sugar transporter, putative | 0.0059 | 0.0146 | 0.0098 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.2319 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Trichomonas vaginalis | prolyl-tRNA synthetase, putative | 0.0125 | 0.0437 | 0.1025 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0048 | 0.01 | 0.026 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0905 | 0.3837 | 1 |
Schistosoma mansoni | protein kinase | 0.0128 | 0.0448 | 0.0402 |
Echinococcus granulosus | solute carrier family 22 | 0.0059 | 0.0146 | 0.038 |
Trypanosoma brucei | glucose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Schistosoma mansoni | lamin | 0.0052 | 0.0118 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0048 | 0.0282 |
Echinococcus multilocularis | lamin | 0.0052 | 0.0118 | 0.0308 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.2319 | 1 | 1 |
Brugia malayi | Major Facilitator Superfamily protein | 0.0059 | 0.0146 | 0.0134 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Chlamydia trachomatis | lysine--tRNA ligase | 0.0093 | 0.0297 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0418 | 0.1713 | 0.1672 |
Brugia malayi | lysyl-tRNA synthetase | 0.0093 | 0.0297 | 0.0285 |
Trypanosoma brucei | glucose transporter 1E | 0.013 | 0.0455 | 0.0409 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0418 | 0.1713 | 0.4463 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.01 | 0.0088 |
Echinococcus granulosus | solute carrier family 22 | 0.0059 | 0.0146 | 0.038 |
Schistosoma mansoni | intermediate filament proteins | 0.0052 | 0.0118 | 0.007 |
Echinococcus multilocularis | solute carrier family 22 | 0.0059 | 0.0146 | 0.038 |
Trypanosoma cruzi | prolyl-tRNA synthetase, putative | 0.0146 | 0.0527 | 0.0481 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Onchocerca volvulus | 0.0052 | 0.0118 | 0.7175 | |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Trypanosoma brucei | glucose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0418 | 0.1713 | 0.1672 |
Trypanosoma cruzi | hexose transporter, putative | 0.0059 | 0.0146 | 0.0098 |
Toxoplasma gondii | calcium-dependent protein kinase CDPK2B | 0.0128 | 0.0448 | 0.0402 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0905 | 0.3837 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0059 | 0.0146 | 0.0098 |
Trypanosoma cruzi | hexose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.2319 | 1 | 1 |
Trypanosoma cruzi | hexose transporter | 0.013 | 0.0455 | 0.0409 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0905 | 0.3837 | 1 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.2319 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0059 | 0.0146 | 0.0258 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.2319 | 1 | 1 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.2319 | 1 | 1 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Plasmodium vivax | CDK-related protein kinase 6, putative | 0.1774 | 0.7627 | 0.7615 |
Plasmodium vivax | calcium-dependent protein kinase 4, putative | 0.0128 | 0.0448 | 0.0402 |
Leishmania major | prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative | 0.0146 | 0.0527 | 0.0481 |
Brugia malayi | hypothetical protein | 0.0059 | 0.0146 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.01 | 0.0583 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0418 | 0.1713 | 0.4463 |
Plasmodium falciparum | calcium-dependent protein kinase 1 | 0.0128 | 0.0448 | 0.0307 |
Plasmodium vivax | hexose transporter | 0.0418 | 0.1713 | 0.1672 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0048 | 0.0282 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.2319 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0048 | 0.0282 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trypanosoma brucei | glucose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Schistosoma mansoni | protein kinase | 0.0128 | 0.0448 | 0.0402 |
Trypanosoma brucei | glucose transporter 2A | 0.013 | 0.0455 | 0.0409 |
Trypanosoma brucei | myo-inositol/proton symporter (MIT) | 0.0059 | 0.0146 | 0.0098 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type | 0.0128 | 0.0448 | 0.1167 |
Schistosoma mansoni | protein kinase | 0.0128 | 0.0448 | 0.0402 |
Loa Loa (eye worm) | MBCTL1 | 0.0055 | 0.0129 | 0.0753 |
Trypanosoma cruzi | lysyl-tRNA synthetase, putative | 0.0093 | 0.0297 | 0.0249 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trypanosoma cruzi | hexose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Toxoplasma gondii | protein kinase, putative | 0.1181 | 0.504 | 0.5016 |
Toxoplasma gondii | lysine-tRNA ligase | 0.0093 | 0.0297 | 0.0249 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Plasmodium falciparum | protein kinase 7 | 0.1181 | 0.504 | 0.4967 |
Mycobacterium ulcerans | prolyl-tRNA synthetase | 0.0044 | 0.0083 | 0.0035 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Toxoplasma gondii | transporter, major facilitator family protein | 0.0059 | 0.0146 | 0.0098 |
Schistosoma mansoni | sugar transporter | 0.0059 | 0.0146 | 0.0098 |
Giardia lamblia | Prolyl-tRNA synthetase | 0.0125 | 0.0437 | 1 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.1713 | 0.4392 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Trichomonas vaginalis | glucose transporter, putative | 0.013 | 0.0455 | 0.1073 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0048 | 0.01 | 0.026 |
Brugia malayi | Major Facilitator Superfamily protein | 0.0059 | 0.0146 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0048 | 0.0282 |
Echinococcus multilocularis | glutamyl tRNA synthetase cytoplasmic | 0.0125 | 0.0437 | 0.1138 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0059 | 0.0146 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0437 | 0.2549 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type 1 | 0.0128 | 0.0448 | 0.1167 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Echinococcus multilocularis | tumor protein p63 | 0.0341 | 0.1378 | 0.3592 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trypanosoma cruzi | hexose transporter, putative | 0.0071 | 0.0199 | 0.0151 |
Plasmodium falciparum | calcium-dependent protein kinase 4 | 0.0128 | 0.0448 | 0.0307 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.2319 | 1 | 1 |
Brugia malayi | intermediate filament protein | 0.0052 | 0.0118 | 0.0106 |
Schistosoma mansoni | lysyl-tRNA synthetase | 0.0093 | 0.0297 | 0.0249 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0418 | 0.1713 | 0.4463 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0048 | 0.01 | 0.0583 |
Trypanosoma brucei | lysyl-tRNA synthetase, putative | 0.0093 | 0.0297 | 0.0249 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0128 | 0.0448 | 0.1167 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Onchocerca volvulus | 0.0052 | 0.0118 | 0.7175 | |
Schistosoma mansoni | glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) | 0.0125 | 0.0437 | 0.039 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0114 | 0.0667 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0905 | 0.3837 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0052 | 0.0118 | 0.0308 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0059 | 0.0146 | 0.0258 |
Echinococcus multilocularis | lamin dm0 | 0.0052 | 0.0118 | 0.0308 |
Brugia malayi | bifunctional aminoacyl-tRNA synthetase | 0.0125 | 0.0437 | 0.0425 |
Echinococcus multilocularis | lysyl tRNA synthetase | 0.0093 | 0.0297 | 0.0773 |
Schistosoma mansoni | sugar transporter | 0.0059 | 0.0146 | 0.0098 |
Brugia malayi | Calcium/calmodulin-dependent protein kinase type II alpha chain | 0.0128 | 0.0448 | 0.0436 |
Plasmodium falciparum | mitogen-activated protein kinase 2 | 0.0676 | 0.2835 | 0.2729 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0048 | 0.01 | 0.0052 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0048 | 0.01 | 0.5275 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0418 | 0.1713 | 0.4463 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Toxoplasma gondii | calcium-dependent protein kinase CDPK3 | 0.0128 | 0.0448 | 0.0402 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0052 | 0.0118 | 0.0106 |
Leishmania major | glucose transporter, lmgt2 | 0.013 | 0.0455 | 0.0409 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0118 | 0.0691 |
Leishmania major | glucose transporter, lmgt1 | 0.013 | 0.0455 | 0.0409 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0418 | 0.1713 | 0.4463 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0128 | 0.0448 | 0.0402 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.2319 | 1 | 1 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.0108 | 0.006 |
Loa Loa (eye worm) | calcium/calmodulin-dependent protein kinase ID | 0.0128 | 0.0448 | 0.2615 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Toxoplasma gondii | prolyl-tRNA synthetase (ProRS) | 0.0146 | 0.0527 | 0.0481 |
Trichomonas vaginalis | sugar transporter, putative | 0.013 | 0.0455 | 0.1073 |
Onchocerca volvulus | Putative transporter | 0.0059 | 0.0146 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0059 | 0.0146 | 0.0258 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0055 | 0.0129 | 0.0336 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Onchocerca volvulus | 0.0048 | 0.01 | 0.5275 | |
Mycobacterium tuberculosis | Lysyl-tRNA synthetase 2 LysX | 0.0079 | 0.0235 | 0.0188 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.01 | 0.0088 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Brugia malayi | Cam kinase protein 1 | 0.0128 | 0.0448 | 0.0436 |
Trichomonas vaginalis | sugar transport protein, putative | 0.0059 | 0.0146 | 0.0258 |
Plasmodium falciparum | calcium-dependent protein kinase 3 | 0.0128 | 0.0448 | 0.0307 |
Schistosoma mansoni | sugar transporter | 0.0059 | 0.0146 | 0.0098 |
Plasmodium falciparum | proline--tRNA ligase | 0.0146 | 0.0527 | 0.0387 |
Entamoeba histolytica | protein kinase, putative | 0.0128 | 0.0448 | 0.0427 |
Entamoeba histolytica | prolyl-tRNA synthetase, putative | 0.0125 | 0.0437 | 0.0395 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Plasmodium falciparum | lysine--tRNA ligase | 0.0093 | 0.0297 | 0.0153 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0905 | 0.3837 | 0.3808 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0048 | 0.01 | 0.026 |
Plasmodium vivax | proline--tRNA ligase, putative | 0.0146 | 0.0527 | 0.0481 |
Schistosoma mansoni | lamin | 0.0052 | 0.0118 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Toxoplasma gondii | sugar transporter ST1 | 0.0059 | 0.0146 | 0.0098 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trichomonas vaginalis | glucose transporter, putative | 0.013 | 0.0455 | 0.1073 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trypanosoma cruzi | sugar transporter, putative | 0.0059 | 0.0146 | 0.0098 |
Echinococcus granulosus | lysyl tRNA synthetase | 0.0093 | 0.0297 | 0.0773 |
Trypanosoma brucei | sugar transporter, putative | 0.0059 | 0.0146 | 0.0098 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0048 | 0.0126 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0048 | 0.0036 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0028 | 0.0012 | 0.0071 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.2319 | 1 | 1 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.2319 | 1 | 1 |
Mycobacterium ulcerans | integral membrane transport protein | 0.0059 | 0.0146 | 0.0098 |
Plasmodium vivax | calcium-dependent protein kinase 3, putative | 0.0128 | 0.0448 | 0.0402 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0128 | 0.0448 | 0.1055 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0048 | 0.0126 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trypanosoma brucei | glucose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Trichomonas vaginalis | glucose transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0418 | 0.1713 | 0.4463 |
Mycobacterium tuberculosis | Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) | 0.0079 | 0.0235 | 0.0188 |
Echinococcus multilocularis | synaptic vesicle 2 protein | 0.0059 | 0.0146 | 0.038 |
Echinococcus granulosus | synaptic vesicle 2 protein | 0.0059 | 0.0146 | 0.038 |
Brugia malayi | hypothetical protein | 0.0059 | 0.0146 | 0.0134 |
Brugia malayi | major facilitator superfamily protein | 0.0059 | 0.0146 | 0.0134 |
Leishmania major | lysyl-tRNA synthetase, putative | 0.0093 | 0.0297 | 0.0249 |
Mycobacterium ulcerans | lysyl-tRNA synthetase | 0.0093 | 0.0297 | 0.0249 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Plasmodium vivax | calcium-dependent protein kinase 1, putative | 0.0128 | 0.0448 | 0.0402 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0905 | 0.3837 | 1 |
Echinococcus multilocularis | solute carrier family 22 | 0.0059 | 0.0146 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0048 | 0.0282 |
Brugia malayi | major facilitator superfamily protein | 0.0059 | 0.0146 | 0.0134 |
Giardia lamblia | Lysyl-tRNA synthetase | 0.0093 | 0.0297 | 0.5182 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Trypanosoma brucei | glucose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Echinococcus granulosus | tumor protein p63 | 0.0341 | 0.1378 | 0.3592 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0905 | 0.3837 | 1 |
Leishmania major | glucose transporter, lmgt3 | 0.013 | 0.0455 | 0.0409 |
Loa Loa (eye worm) | major facilitator superfamily transporter | 0.0059 | 0.0146 | 0.0852 |
Toxoplasma gondii | cell-cycle-associated protein kinase MAPK, putative | 0.0676 | 0.2835 | 0.2801 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0194 | 0.0734 | 0.1913 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0297 | 0.1731 |
Trypanosoma brucei | calcium/calmodulin-dependent protein kinase, putative | 0.0128 | 0.0448 | 0.0402 |
Toxoplasma gondii | calcium-dependent protein kinase CDPK2A | 0.0128 | 0.0448 | 0.0402 |
Trichomonas vaginalis | lysyl-tRNA synthetase, putative | 0.0093 | 0.0297 | 0.0655 |
Brugia malayi | Sugar transporter family protein | 0.0059 | 0.0146 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Mycobacterium ulcerans | lysyl-tRNA synthetase | 0.0093 | 0.0297 | 0.0249 |
Loa Loa (eye worm) | sugar transporter | 0.0418 | 0.1713 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0052 | 0.0118 | 0.0691 |
Schistosoma mansoni | sugar transporter | 0.0059 | 0.0146 | 0.0098 |
Echinococcus multilocularis | General substrate transporter | 0.0359 | 0.1456 | 0.3795 |
Trichomonas vaginalis | myo-inositol transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Brugia malayi | Sugar transporter family protein | 0.0418 | 0.1713 | 0.1703 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Trypanosoma brucei | glucose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0108 | 0.0628 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0059 | 0.0146 | 0.0258 |
Plasmodium vivax | calcium-dependent protein kinase, putative | 0.0128 | 0.0448 | 0.0402 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase type | 0.0128 | 0.0448 | 0.1167 |
Schistosoma mansoni | glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) | 0.0125 | 0.0437 | 0.039 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0418 | 0.1713 | 0.4463 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0334 | 0.195 |
Mycobacterium leprae | Probable prolyl tRNA synthetase ProS | 0.0125 | 0.0437 | 0.039 |
Schistosoma mansoni | hypothetical protein | 0.0418 | 0.1713 | 0.1672 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Leishmania major | dihydroorotate dehydrogenase | 0.2319 | 1 | 1 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.013 | 0.0455 | 0.0409 |
Plasmodium falciparum | calcium-dependent protein kinase 5 | 0.0128 | 0.0448 | 0.0307 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Mycobacterium ulcerans | sugar-transport integral membrane protein SugI | 0.0059 | 0.0146 | 0.0098 |
Trypanosoma brucei | bifunctional aminoacyl-tRNA synthetase, putative | 0.0146 | 0.0527 | 0.0481 |
Trypanosoma cruzi | prolyl-tRNA synthetase, putative | 0.0146 | 0.0527 | 0.0481 |
Echinococcus granulosus | General substrate transporter | 0.0359 | 0.1456 | 0.3795 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0055 | 0.0129 | 0.0117 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0052 | 0.0118 | 0.0691 |
Loa Loa (eye worm) | CAMK/CAMK2 protein kinase | 0.0128 | 0.0448 | 0.2615 |
Toxoplasma gondii | sugar transporter ST3 | 0.0059 | 0.0146 | 0.0098 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Loa Loa (eye worm) | bifunctional aminoacyl-tRNA synthetase | 0.0051 | 0.0114 | 0.0666 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0055 | 0.0129 | 0.0336 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0786 | 0.3317 | 0.8644 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0055 | 0.0129 | 0.0081 |
Leishmania major | protein kinase, putative | 0.0128 | 0.0448 | 0.0402 |
Trichomonas vaginalis | conserved hypothetical protein | 0.013 | 0.0455 | 0.1073 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0048 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0128 | 0.0448 | 0.1167 |
Trichomonas vaginalis | lysyl-tRNA synthetase, putative | 0.0082 | 0.0246 | 0.0523 |
Echinococcus multilocularis | solute carrier family 22 | 0.0059 | 0.0146 | 0.038 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Loa Loa (eye worm) | sugar transporter | 0.0059 | 0.0146 | 0.0852 |
Echinococcus multilocularis | solute carrier family 22 | 0.0059 | 0.0146 | 0.038 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Echinococcus multilocularis | musashi | 0.0052 | 0.0118 | 0.0308 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0905 | 0.3837 | 1 |
Echinococcus multilocularis | calcium dependent protein kinase | 0.012 | 0.0413 | 0.1077 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0055 | 0.0129 | 0.0336 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0048 | 0.0282 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Plasmodium vivax | mitogen-activated protein kinase 2, putative | 0.0676 | 0.2835 | 0.2801 |
Echinococcus granulosus | Sugar transporter ERD6 protein | 0.0059 | 0.0146 | 0.038 |
Echinococcus granulosus | calcium dependent protein kinase | 0.012 | 0.0413 | 0.1077 |
Loa Loa (eye worm) | major facilitator superfamily transporter | 0.0059 | 0.0146 | 0.0852 |
Plasmodium falciparum | hexose transporter | 0.0418 | 0.1713 | 0.159 |
Schistosoma mansoni | nuclear transcription factor X-box binding 1 (nfx1) | 0.0059 | 0.0146 | 0.0098 |
Mycobacterium leprae | Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) | 0.0079 | 0.0235 | 0.0188 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0232 | 0.0903 | 0.0859 |
Echinococcus granulosus | glutamyl tRNA synthetase cytoplasmic | 0.0125 | 0.0437 | 0.1138 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0128 | 0.0448 | 0.1167 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Mycobacterium ulcerans | sugar transporter | 0.0059 | 0.0146 | 0.0098 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase type | 0.0128 | 0.0448 | 0.1167 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Mycobacterium tuberculosis | Probable conserved integral membrane transport protein | 0.0059 | 0.0146 | 0.0098 |
Trypanosoma cruzi | glucose transporter, putative | 0.0059 | 0.0146 | 0.0098 |
Echinococcus multilocularis | Sugar transporter ERD6 protein | 0.0059 | 0.0146 | 0.038 |
Plasmodium falciparum | protein kinase 6 | 0.1774 | 0.7627 | 0.7592 |
Trypanosoma brucei | glucose transporter, putative | 0.013 | 0.0455 | 0.0409 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0146 | 0.0852 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0905 | 0.3837 | 1 |
Brugia malayi | hypothetical protein | 0.0059 | 0.0146 | 0.0134 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.01 | 0.0052 |
Schistosoma mansoni | glucose transport protein | 0.0418 | 0.1713 | 0.1672 |
Schistosoma mansoni | hypothetical protein | 0.0297 | 0.1183 | 0.1141 |
Entamoeba histolytica | protein kinase, putative | 0.0128 | 0.0448 | 0.0427 |
Schistosoma mansoni | glucose transport protein | 0.0418 | 0.1713 | 0.1672 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0129 | 0.0753 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0905 | 0.3837 | 0.383 |
Echinococcus granulosus | lamin dm0 | 0.0052 | 0.0118 | 0.0308 |
Brugia malayi | Bifunctional aminoacyl-tRNA synthetase | 0.0125 | 0.0437 | 0.0425 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Mycobacterium tuberculosis | Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) | 0.0059 | 0.0146 | 0.0098 |
Treponema pallidum | prolyl-tRNA synthetase | 0.0044 | 0.0083 | 0.5 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0194 | 0.0734 | 0.1913 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.0448 | 0.2615 |
Trichomonas vaginalis | sugar transporter, putative | 0.013 | 0.0455 | 0.1073 |
Mycobacterium ulcerans | fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT | 0.0059 | 0.0146 | 0.0098 |
Echinococcus granulosus | solute carrier family 22 | 0.0059 | 0.0146 | 0.038 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Onchocerca volvulus | 0.0059 | 0.0146 | 1 | |
Echinococcus granulosus | lamin | 0.0052 | 0.0118 | 0.0308 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0048 | 0.01 | 0.026 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0048 | 0.0036 |
Trichomonas vaginalis | sugar transporter, putative | 0.0059 | 0.0146 | 0.0258 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -5.562 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.45 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.204 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.116 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.871 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.858 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.83 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.755 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.754 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.747 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.702 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.