Detailed information for compound 1635411

Basic information

Technical information
  • TDR Targets ID: 1635411
  • Name: 5-(5-sulfinopentylsulfanyldisulfanyl)pentane- 1-sulfinic acid
  • MW: 366.604 | Formula: C10H22O4S5
  • H donors: 2 H acceptors: 4 LogP: 1.84 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 1
  • SMILES: OS(=O)CCCCCSSSCCCCCS(=O)O
  • InChi: 1S/C10H22O4S5/c11-18(12)9-5-1-3-7-15-17-16-8-4-2-6-10-19(13)14/h1-10H2,(H,11,12)(H,13,14)
  • InChiKey: IHKYEXFUJIUKGT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-(5-sulfinopentylthio)disulfanylpentane-1-sulfinic acid
  • AIDS-156505
  • AIDS156505
  • NCI60_007251
  • NSC624192 (SODIUM SALT)
  • 1-Pentanesulfinic acid, 5,5'-(1,3-trisulfanediyl)bis-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0092 0.0079 0.0079
Loa Loa (eye worm) phosphatidylinositol 3 0.1447 0.3351 0.3351
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.034 0.0678 0.0658
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.4202 1 1
Echinococcus granulosus serine protein kinase ATM 0.0813 0.182 0.1754
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.032 0.0631 0.0523
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.4202 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.2503 0.5899 0.589
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0281 0.0536 0.0516
Trichomonas vaginalis PIKK family atypical protein kinase 0.1129 0.2583 0.2566
Schistosoma mansoni phosphatidylinositol 4-kinase 0.03 0.0583 0.0508
Echinococcus multilocularis fk506 binding protein 0.0106 0.0114 0.0036
Loa Loa (eye worm) hypothetical protein 0.0624 0.1364 0.1364
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.03 0.0583 0.0572
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0106 0.0114 0.0114
Loa Loa (eye worm) AGC/AKT protein kinase 0.0068 0.0022 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0268 0.019
Loa Loa (eye worm) phosphatidylinositol 3 0.0281 0.0536 0.0536
Trichomonas vaginalis PIKK family atypical protein kinase 0.2727 0.6439 0.6432
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0532 0.1141 0.1141
Loa Loa (eye worm) hypothetical protein 0.0848 0.1904 0.1904
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0408 0.0843 0.0823
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0188 0.031 0.0299
Trichomonas vaginalis PIKK family atypical protein kinase 0.1437 0.3325 0.3311
Entamoeba histolytica protein kinase rad3, putative 0.0813 0.182 0.181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0281 0.0536 0.0516
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0813 0.182 0.1754
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0281 0.0536 0.0536
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.03 0.0583 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.4202 1 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.034 0.0678 0.0668
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0281 0.0536 0.0707
Trichomonas vaginalis PIKK family atypical protein kinase 0.3136 0.7427 0.7421
Trichomonas vaginalis PIKK family atypical protein kinase 0.2288 0.538 0.537
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0534 0.1146 0.1076
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0813 0.182 0.182
Entamoeba histolytica hypothetical protein 0.0281 0.0536 0.0525
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1447 0.3351 0.3337
Trichomonas vaginalis PIKK family atypical protein kinase 0.335 0.7945 0.7941
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.03 0.0583 0.0771
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0639 0.14 0.1331
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.034 0.0678 0.0668
Trichomonas vaginalis PIKK family atypical protein kinase 0.2288 0.538 0.537
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0281 0.0536 0.8998
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1447 0.3351 0.3274
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.03 0.0583 0.0508
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.4202 1 1
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.03 0.0583 0.0583
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0281 0.0536 0.0461
Trichomonas vaginalis fk506-binding protein, putative 0.0106 0.0114 0.0093
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.03 0.0583 0.0771
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.03 0.0583 0.0508
Trichomonas vaginalis PIKK family atypical protein kinase 0.3578 0.8494 0.8491
Trichomonas vaginalis PIKK family atypical protein kinase 0.335 0.7945 0.7941
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0281 0.0536 0.0525
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.03 0.0583 0.0474
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.198 0.4637 0.4626
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0281 0.0536 0.0516
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.04 0.0824 0.0751
Trypanosoma cruzi hypothetical protein, conserved 0.009 0.0074 0.0074
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0469 0.0989 0.0969
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0156 0.0233 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.2503 0.5899 0.589
Trichomonas vaginalis PIKK family atypical protein kinase 0.0281 0.0536 0.0516
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0106 0.0114 0.0114
Entamoeba histolytica hypothetical protein 0.0281 0.0536 0.0525
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.034 0.0678 0.0668
Entamoeba histolytica hypothetical protein 0.0429 0.0893 0.0883
Loa Loa (eye worm) hypothetical protein 0.0532 0.1141 0.1141
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0106 0.0114 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.2284 0.5372 0.5362
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0281 0.0536 0.8998
Brugia malayi FAT domain containing protein 0.0624 0.1364 0.1354
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.03 0.0583 0.0572
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.03 0.0583 0.0508
Trichomonas vaginalis PIKK family atypical protein kinase 0.2512 0.5921 0.5912
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0624 0.1364 0.1295
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0469 0.0989 0.0969
Trypanosoma brucei target of rapamycin kinase 3, putative 0.3354 0.7954 0.7949
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0281 0.0536 0.0536
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0813 0.182 0.182
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0281 0.0536 0.0536
Trichomonas vaginalis PIKK family atypical protein kinase 0.335 0.7945 0.7941
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0106 0.0114 0.0103
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0281 0.0536 0.0516
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0281 0.0536 0.0461
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.034 0.0678 0.0658
Toxoplasma gondii FATC domain-containing protein 0.0813 0.182 0.2438
Loa Loa (eye worm) hypothetical protein 0.0068 0.0022 0.0022
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0469 0.0989 0.0969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0532 0.1141 0.1122
Trichomonas vaginalis PIKK family atypical protein kinase 0.2288 0.538 0.537
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0281 0.0536 0.0707
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0813 0.182 0.181
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0106 0.0114 0.0093
Plasmodium vivax hypothetical protein 0.0281 0.0536 0.8998
Trichomonas vaginalis PIKK family atypical protein kinase 0.3136 0.7427 0.7421
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0106 0.0114 0.0114
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0429 0.0893 0.0883
Giardia lamblia GTOR 0.4202 1 1
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.03 0.0583 0.0572
Loa Loa (eye worm) phosphatidylinositol 3 0.0281 0.0536 0.0536
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0106 0.0114 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.335 0.7945 0.7941
Schistosoma mansoni fkbp-rapamycin associated protein 0.0813 0.182 0.1754
Trichomonas vaginalis PIKK family atypical protein kinase 0.4202 1 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.1437 0.3325 0.3248
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0813 0.182 0.181
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1486 0.3445 0.3393
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0281 0.0536 0.0461
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.03 0.0583 0.0583
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0281 0.0536 0.0525
Leishmania major hypothetical protein, conserved 0.0371 0.0752 0.0645
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0106 0.0114 0.0093
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1486 0.3445 0.3445
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1486 0.3445 0.3438
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0624 0.1364 0.1295
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0361 0.0729 0.0718
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0156 0.0233 0.0222
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0281 0.0536 0.0707
Entamoeba histolytica protein kinase, putative 0.0068 0.0022 0.001
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0106 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.04 0.0824 0.0824
Loa Loa (eye worm) FKBP5 protein 0.0106 0.0114 0.0114
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0905 0.2042 0.2738
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0281 0.0536 0.8998
Loa Loa (eye worm) phosphatidylinositol 3 0.4202 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.2512 0.5921 0.5912
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1437 0.3325 0.3311
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1486 0.3445 0.3393
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0268 0.019
Trichomonas vaginalis immunophilin, putative 0.0106 0.0114 0.0093
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1486 0.3445 0.3445
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.4202 1 1
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.034 0.0678 0.0604
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.034 0.0678 0.0658
Brugia malayi Protein kinase domain containing protein 0.0068 0.0022 0.001
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0813 0.182 0.1802
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0064 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0624 0.1364 0.1345
Leishmania major phosphatidylinositol kinase, putative 0.0281 0.0536 0.0427
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0281 0.0536 0.0516
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0813 0.182 0.1754
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0469 0.0989 0.0989
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0281 0.0536 0.0461
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0106 0.0114 0.0093
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0469 0.0989 0.0989
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0106 0.0114 0.0036
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0106 0.0114 0.0093
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0106 0.0114 0.0103
Loa Loa (eye worm) hypothetical protein 0.0905 0.2042 0.2042
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.4202 1 1
Trypanosoma cruzi target of rapamycin kinase 3 0.3354 0.7954 0.7954
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0281 0.0536 0.0461
Trichomonas vaginalis PIKK family atypical protein kinase 0.2284 0.5372 0.5362
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0281 0.0536 0.0536
Trichomonas vaginalis PIKK family atypical protein kinase 0.2512 0.5921 0.5912
Trichomonas vaginalis PIKK family atypical protein kinase 0.3136 0.7427 0.7421
Toxoplasma gondii target of rapamycin (TOR), putative 0.3136 0.7427 1
Plasmodium vivax hypothetical protein, conserved 0.0281 0.0536 0.8998
Leishmania major phosphatidylinositol 3-kinase, putative 0.03 0.0583 0.0474
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.03 0.0583 0.0583
Echinococcus multilocularis 0.0281 0.0536 0.0461
Trichomonas vaginalis PIKK family atypical protein kinase 0.3136 0.7427 0.7421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0813 0.182 0.1802
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0281 0.0536 0.8998
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.03 0.0583 0.0563
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1486 0.3445 0.3393
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.4202 1 1
Echinococcus multilocularis Zinc finger, PHD finger 0.03 0.0583 0.0508
Leishmania major hypothetical protein, unknown function 0.0281 0.0536 0.0427
Trichomonas vaginalis PIKK family atypical protein kinase 0.3136 0.7427 0.7421
Schistosoma mansoni hypothetical protein 0.0281 0.0536 0.0461
Onchocerca volvulus 0.0281 0.0536 0.5
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0281 0.0536 0.0525
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0106 0.0114 0.5
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0639 0.14 0.1331
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.3354 0.7954 0.793
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0156 0.0233 0.0233
Entamoeba histolytica hypothetical protein 0.0813 0.182 0.181
Trichomonas vaginalis PIKK family atypical protein kinase 0.3136 0.7427 0.7421
Trichomonas vaginalis PIKK family atypical protein kinase 0.2819 0.6662 0.6655
Mycobacterium leprae conserved hypothetical protein 0.0281 0.0536 0.5
Entamoeba histolytica hypothetical protein 0.0281 0.0536 0.0525
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0639 0.14 0.1331
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0145 0.0209 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0905 0.2042 0.2025
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.4202 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0823 0.1845 0.1827
Loa Loa (eye worm) hypothetical protein 0.0281 0.0536 0.0536
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0469 0.0989 0.0978
Giardia lamblia Phosphatidylinositol 4-kinase 0.0281 0.0536 0.0427
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.034 0.0678 0.0658
Loa Loa (eye worm) phosphatidylinositol kinase 0.0281 0.0536 0.0536
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0106 0.0114 0.0114
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.04 0.0824 0.0814
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0281 0.0536 0.0536
Trichomonas vaginalis PIKK family atypical protein kinase 0.4202 1 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.4202 1 1
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0281 0.0536 0.8998
Trichomonas vaginalis PIKK family atypical protein kinase 0.1437 0.3325 0.3311
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0813 0.182 0.1754
Trichomonas vaginalis PIKK family atypical protein kinase 0.1447 0.3351 0.3337
Mycobacterium tuberculosis Conserved hypothetical protein 0.0281 0.0536 0.5
Echinococcus multilocularis serine protein kinase ATM 0.0813 0.182 0.1754
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0281 0.0536 0.0525
Loa Loa (eye worm) phosphatidylinositol 3 0.0281 0.0536 0.0536
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.4202 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.2284 0.5372 0.5362
Leishmania major phosphatidylinositol kinase related protein, putative 0.0281 0.0536 0.0427
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0145 0.0209 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.2288 0.538 0.537
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0281 0.0536 0.0461
Trichomonas vaginalis PIKK family atypical protein kinase 0.335 0.7945 0.7941
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0534 0.1146 0.1076
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0281 0.0536 0.0461
Trichomonas vaginalis PIKK family atypical protein kinase 0.0813 0.182 0.1802
Giardia lamblia Hypothetical protein 0.0281 0.0536 0.0427
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0369 0.0747 0.0641
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0106 0.0114 0.5
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.017 0.0269 0.0257
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0469 0.0989 0.0978
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.04 0.0824 0.0751
Loa Loa (eye worm) hypothetical protein 0.0135 0.0184 0.0184
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0106 0.0114 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.3136 0.7427 0.7421
Loa Loa (eye worm) hypothetical protein 0.0813 0.182 0.182
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.03 0.0583 0.0508
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0156 0.0233 0.0156
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.03 0.0583 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0532 0.1141 0.1122
Loa Loa (eye worm) phosphatidylinositol 3 0.0599 0.1304 0.1304
Loa Loa (eye worm) phosphatidylinositol 3 0.0281 0.0536 0.0536
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.03 0.0583 0.0563
Trichomonas vaginalis PIKK family atypical protein kinase 0.1437 0.3325 0.3311
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0106 0.0114 0.0103
Entamoeba histolytica protein kinase, putative 0.0068 0.0022 0.001
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.4202 1 1
Schistosoma mansoni immunophilin 0.0106 0.0114 0.0036
Leishmania major phosphatidylinositol 4-kinase, putative 0.0281 0.0536 0.0427
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0106 0.0114 0.0036
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0408 0.0843 0.0823
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.1756 0.4097 0.4084
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0281 0.0536 0.0461
Schistosoma mansoni immunophilin 0.0106 0.0114 0.0036
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0823 0.1845 0.1836
Trichomonas vaginalis PIKK family atypical protein kinase 0.1437 0.3325 0.3311
Schistosoma mansoni hypothetical protein 0.0624 0.1364 0.1295
Plasmodium falciparum phosphatidylinositol 3-kinase 0.03 0.0583 1
Onchocerca volvulus 0.0281 0.0536 0.5
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.034 0.0678 0.0678
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.03 0.0583 0.0563
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.4202 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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