Detailed information for compound 1642130

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1718.68 | Formula: C82H106Cl2N10O26
  • H donors: 20 H acceptors: 18 LogP: 1.67 Rotable bonds: 25
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCCCCCCN[C@@]1(C)C[C@H](O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)CO)Oc2c3Oc4ccc(cc4Cl)[C@@H](O)[C@@H](NC(=O)[C@@H](CC(C)C)NC)C(=O)N[C@H](C(=O)N[C@@H]4c(c3)cc2Oc2ccc(cc2Cl)[C@@H](O[C@@H]2O[C@@H](C)[C@H]([C@@](C2)(C)N)O)[C@@H]2NC(=O)[C@H](NC4=O)c3ccc(c(c3)c3c(O)cc(cc3[C@@H](NC2=O)C(=O)O)O)O)CC(=O)N)O[C@H]([C@H]1O)C
  • InChi: 1S/C82H106Cl2N10O26/c1-9-10-11-12-13-14-15-22-88-82(7)33-58(114-37(5)72(82)104)119-70-67(102)66(101)55(34-95)117-80(70)120-69-53-27-41-28-54(69)116-52-21-18-40(26-46(52)84)68(118-57-32-81(6,86)71(103)36(4)113-57)64-78(110)92-62(79(111)112)44-29-42(96)30-50(98)59(44)43-24-38(16-19-49(43)97)60(75(107)94-64)91-76(108)61(41)90-74(106)48(31-56(85)99)89-77(109)63(93-73(105)47(87-8)23-35(2)3)65(100)39-17-20-51(115-53)45(83)25-39/h16-21,24-30,35-37,47-48,55,57-58,60-68,70-72,80,87-88,95-98,100-104H,9-15,22-23,31-34,86H2,1-8H3,(H2,85,99)(H,89,109)(H,90,106)(H,91,108)(H,92,110)(H,93,105)(H,94,107)(H,111,112)/t36-,37-,47+,48-,55+,57-,58-,60+,61+,62+,63+,64-,65+,66+,67-,68+,70+,71+,72+,80-,81-,82-/m0/s1
  • InChiKey: YTPWPEGAWFMAOM-IHWGOTMWSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable lipase LipE 0.0029 0.0089 0.0113
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0159 0.2522 0.2522
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0089 0.0089
Leishmania major heat shock protein 83-1 0.0558 1 1
Toxoplasma gondii thioredoxin reductase 0.0071 0.0873 0.0873
Loa Loa (eye worm) hypothetical protein 0.0114 0.1668 0.1593
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0112 0.1632 0.1632
Giardia lamblia Heat shock protein HSP 90-alpha 0.0444 0.7869 0.7869
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni tensin 0.0159 0.2522 0.2522
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0114 0.1668 0.1668
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0444 0.7869 1
Schistosoma mansoni pyruvate dehydrogenase 0.0114 0.1668 0.1668
Brugia malayi Tyrosine-protein kinase PR2 0.0112 0.1632 0.1632
Loa Loa (eye worm) TK protein kinase 0.0112 0.1632 0.1557
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0112 0.1632 0.1632
Echinococcus granulosus integrin linked protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0861 0.0861
Loa Loa (eye worm) TK protein kinase 0.0112 0.1632 0.1557
Brugia malayi Tensin 0.0159 0.2522 0.2522
Loa Loa (eye worm) SH2 domain-containing protein 0.0159 0.2522 0.2455
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Leishmania major heat shock protein 83-1 0.0558 1 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0114 0.1668 0.212
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.1632 0.1632
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0114 0.1668 0.1668
Onchocerca volvulus 0.0112 0.1632 0.3408
Loa Loa (eye worm) TK protein kinase 0.0112 0.1632 0.1557
Schistosoma mansoni hypothetical protein 0.0159 0.2522 0.2522
Echinococcus granulosus tyrosine protein kinase Src42A 0.0159 0.2522 0.2522
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1857 0.1857
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0114 0.1668 0.212
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0112 0.1632 0.1557
Leishmania major trypanothione reductase 0.0071 0.0873 0.0873
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis transfer RNA-Thr 0.0112 0.1632 0.1632
Trypanosoma brucei heat shock protein, putative 0.0558 1 1
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni GTPase activating protein 0.0159 0.2522 0.2522
Treponema pallidum heat shock protein 90 0.0444 0.7869 1
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.1632 0.1632
Schistosoma mansoni cellular tumor antigen P53 0.0046 0.0391 0.0391
Onchocerca volvulus 0.0159 0.2522 0.5373
Loa Loa (eye worm) TK/EGFR protein kinase 0.0112 0.1632 0.1557
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0112 0.1632 0.1557
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Brugia malayi latrophilin 2 splice variant baaae 0.013 0.1981 0.1981
Echinococcus multilocularis tensin 0.0159 0.2522 0.2522
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trypanosoma cruzi protein kinase, putative 0.0112 0.1632 0.1632
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0861 0.0861
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Brugia malayi Cytochrome P450 family protein 0.0057 0.0603 0.0603
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0114 0.1668 0.212
Loa Loa (eye worm) TK/RYK protein kinase 0.0112 0.1632 0.1557
Trypanosoma cruzi DNA topoisomerase II, putative 0.0114 0.1668 0.1668
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0159 0.2522 0.2522
Echinococcus granulosus activated cdc42 kinase 1 0.0112 0.1632 0.1632
Echinococcus multilocularis insulin receptor 0.0112 0.1632 0.1632
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0162 0.2584 0.3283
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0271 0.4616 0.4616
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni tyrosine kinase 0.0271 0.4616 0.4616
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0159 0.2522 0.2522
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0159 0.2522 0.2455
Echinococcus multilocularis tyrosine protein kinase pr2 0.0112 0.1632 0.1632
Brugia malayi hypothetical protein 0.0271 0.4616 0.4616
Loa Loa (eye worm) TK/FER protein kinase 0.0271 0.4616 0.4568
Echinococcus multilocularis tyrosine protein kinase Abl 0.0271 0.4616 0.4616
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Leishmania major heat shock protein 83-1 0.0558 1 1
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Loa Loa (eye worm) hypothetical protein 0.0046 0.0391 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.1632 0.1632
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0159 0.2522 0.2522
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0271 0.4616 0.4616
Mycobacterium ulcerans heat shock protein 90 0.0444 0.7869 1
Mycobacterium tuberculosis Probable two component sensor kinase 0.0114 0.1668 0.212
Mycobacterium tuberculosis Conserved protein 0.0029 0.0089 0.0113
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Echinococcus granulosus tyrosine kinase 0.0271 0.4616 0.4616
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0112 0.1632 0.1632
Echinococcus granulosus protein tyrosine kinase 0.0112 0.1632 0.1632
Echinococcus granulosus tyrosine protein kinase Fyn 0.0271 0.4616 0.4616
Echinococcus granulosus tyrosine protein kinase pr2 0.0112 0.1632 0.1632
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0271 0.4616 0.4616
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.3824 0.3824
Brugia malayi beta-lactamase family protein 0.0029 0.0089 0.0089
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0271 0.4616 0.4616
Echinococcus granulosus SH2 motif 0.0159 0.2522 0.2522
Echinococcus multilocularis activated cdc42 kinase 1 0.0112 0.1632 0.1632
Leishmania major heat shock protein 83-1 0.0558 1 1
Plasmodium falciparum protein kinase, putative 0.0112 0.1632 0.1632
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0159 0.2522 0.2522
Toxoplasma gondii STE kinase 0.0112 0.1632 0.1632
Echinococcus granulosus ephrin type A receptor 4 A 0.0112 0.1632 0.1632
Trypanosoma brucei heat shock protein, putative 0.0558 1 1
Mycobacterium leprae Probable two-component sensor kinase 0.0114 0.1668 0.203
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Entamoeba histolytica ankyrin repeat protein 0.0112 0.1632 0.1353
Echinococcus granulosus retinal guanylyl cyclase 2 0.0112 0.1632 0.1632
Trypanosoma cruzi heat shock protein 90, putative 0.0444 0.7869 0.7869
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.019 0.3112 0.3112
Loa Loa (eye worm) hypothetical protein 0.0114 0.1668 0.1593
Entamoeba histolytica protein kinase, putative 0.0159 0.2522 0.2272
Echinococcus multilocularis kinase suppressor of Ras 1 0.0112 0.1632 0.1632
Loa Loa (eye worm) TK/ROR protein kinase 0.0112 0.1632 0.1557
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Leishmania major heat shock protein 83-1 0.0558 1 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0271 0.4616 0.4616
Trypanosoma cruzi PAB1-binding protein , putative 0.0039 0.0271 0.0271
Plasmodium falciparum endoplasmin, putative 0.0342 0.5955 0.5955
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0159 0.2522 0.2522
Echinococcus multilocularis beta LACTamase domain containing family member 0.0029 0.0089 0.0089
Brugia malayi Protein kinase domain containing protein 0.0271 0.4616 0.4616
Brugia malayi SH2 domain containing protein 0.0271 0.4616 0.4616
Echinococcus granulosus activin receptor type 0.0112 0.1632 0.1632
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0114 0.1668 0.1668
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0112 0.1632 0.1632
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0746 0.0746
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0112 0.1632 0.1632
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0114 0.1668 0.212
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0029 0.0089 0.0089
Echinococcus multilocularis FL cytokine receptor 0.0112 0.1632 0.1632
Entamoeba histolytica tyrosin kinase, putative 0.0112 0.1632 0.1353
Loa Loa (eye worm) TK/FER protein kinase 0.0271 0.4616 0.4568
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0029 0.0089 0.0113
Trichomonas vaginalis penicillin-binding protein, putative 0.0029 0.0089 0.0089
Trichomonas vaginalis sensor histidine kinase, putative 0.0114 0.1668 0.1668
Brugia malayi hypothetical protein 0.0039 0.0271 0.0271
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0444 0.7869 0.7869
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0114 0.1668 0.1668
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Echinococcus granulosus tyrosine kinase 0.0271 0.4616 0.4616
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0114 0.1668 0.1668
Trichomonas vaginalis TK family protein kinase 0.0112 0.1632 0.1632
Brugia malayi hypothetical protein 0.0112 0.1632 0.1632
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0114 0.1668 0.212
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0159 0.2522 0.2455
Mycobacterium ulcerans two component sensor kinase MprB 0.0114 0.1668 0.212
Onchocerca volvulus 0.0159 0.2522 0.5373
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Echinococcus granulosus tumor protein p63 0.0311 0.5371 0.5371
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0159 0.2522 0.5373
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.1632 0.1632
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0114 0.1668 0.212
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Echinococcus granulosus epidermal growth factor receptor 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.1632 0.1632
Brugia malayi cytokine inducible SH2-containing protein 5 0.0159 0.2522 0.2522
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus granulosus hypothetical protein 0.0159 0.2522 0.2522
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Mycobacterium tuberculosis Conserved protein 0.0029 0.0089 0.0113
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.1632 0.1557
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0271 0.4616 0.4616
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0271 0.4616 0.4616
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis receptor histidine kinase, putative 0.0114 0.1668 0.1668
Entamoeba histolytica ankyrin repeat protein 0.0112 0.1632 0.1353
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0114 0.1668 0.212
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Chlamydia trachomatis DNA gyrase subunit B 0.0114 0.1668 1
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0114 0.1668 0.1668
Echinococcus granulosus heat shock protein 90 0.0444 0.7869 0.7869
Echinococcus multilocularis protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) TK/FER protein kinase 0.0271 0.4616 0.4568
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0112 0.1632 0.1632
Echinococcus granulosus retinal guanylyl cyclase 2 0.0112 0.1632 0.1632
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0159 0.2522 0.2522
Leishmania major heat shock protein 83-1 0.0558 1 1
Mycobacterium tuberculosis Conserved protein 0.0114 0.1668 0.212
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0159 0.2522 0.5373
Brugia malayi hypothetical protein 0.0112 0.1632 0.1632
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0114 0.1668 0.1668
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0124 0.1857 0.1784
Echinococcus multilocularis tar DNA binding protein 0.0124 0.1857 0.1857
Giardia lamblia Protein 21.1 0.0112 0.1632 0.1632
Loa Loa (eye worm) TAR-binding protein 0.0124 0.1857 0.1784
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0159 0.2522 0.2522
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0089 0.0089
Echinococcus multilocularis tyrosine protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1857 0.1857
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Plasmodium vivax endoplasmin, putative 0.0558 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0271 0.4616 0.4616
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0271 0.4616 0.4616
Brugia malayi bone morphogenetic protein type 1 receptor 0.0112 0.1632 0.1632
Brugia malayi SH2 domain containing protein 0.0159 0.2522 0.2522
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0271 0.4616 0.4616
Mycobacterium ulcerans hypothetical protein 0.0029 0.0089 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Brugia malayi TAR-binding protein 0.0124 0.1857 0.1857
Echinococcus multilocularis natriuretic peptide receptor 1 0.0112 0.1632 0.1632
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Echinococcus multilocularis SHC transforming protein 3 0.0159 0.2522 0.2522
Loa Loa (eye worm) TK/FER protein kinase 0.0271 0.4616 0.4568
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0271 0.4616 0.4568
Schistosoma mansoni shc transforming protein 0.0159 0.2522 0.2522
Plasmodium falciparum DNA topoisomerase 2 0.0114 0.1668 0.1668
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Plasmodium falciparum thioredoxin reductase 0.0071 0.0873 0.0873
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0114 0.1668 0.1668
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0112 0.1632 0.1632
Echinococcus multilocularis tyrosine protein kinase csk 0.0112 0.1632 0.1632
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0114 0.1668 0.1668
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.1632 0.1557
Brugia malayi Variant SH3 domain containing protein 0.0159 0.2522 0.2522
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0861 0.0861
Echinococcus multilocularis SH2 motif 0.0159 0.2522 0.2522
Brugia malayi RNA binding protein 0.0124 0.1857 0.1857
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0114 0.1668 0.212
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) pigment dispersing factor receptor c 0.019 0.3112 0.305
Schistosoma mansoni heat shock protein 0.0558 1 1
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Leishmania major protein kinase, putative 0.0112 0.1632 0.1632
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis integrin linked protein kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis endoplasmin 0.0444 0.7869 0.7869
Entamoeba histolytica tyrosin kinase, putative 0.0112 0.1632 0.1353
Leishmania major heat shock protein 83-1 0.0558 1 1
Brugia malayi integrin-linked kinase 0.0112 0.1632 0.1632
Schistosoma mansoni tyrosine kinase 0.0271 0.4616 0.4616
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0112 0.1632 0.1632
Mycobacterium ulcerans beta-lactamase 0.0029 0.0089 0.0113
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.006 0.0668 0.0668
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0159 0.2522 0.2455
Loa Loa (eye worm) SH2 domain-containing protein 0.0159 0.2522 0.2455
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Trypanosoma cruzi heat shock protein 85, putative 0.0558 1 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0271 0.4616 0.4616
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Trichomonas vaginalis penicillin-binding protein, putative 0.0029 0.0089 0.0089
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.018 0.2923 0.3715
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Loa Loa (eye worm) SH2 domain-containing protein 0.0159 0.2522 0.2455
Loa Loa (eye worm) TK protein kinase 0.0112 0.1632 0.1557
Loa Loa (eye worm) TK/Met protein kinase 0.0112 0.1632 0.1557
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Trichomonas vaginalis heat shock protein, putative 0.0342 0.5955 0.5955
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0112 0.1632 0.1632
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni hypothetical protein 0.013 0.1981 0.1981
Loa Loa (eye worm) TK/FER protein kinase 0.0271 0.4616 0.4568
Plasmodium vivax DNA gyrase subunit B, putative 0.0114 0.1668 0.1668
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0271 0.4616 0.4437
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1857 0.1857
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Trypanosoma brucei Heat shock protein 83, putative 0.0558 1 1
Brugia malayi beta-lactamase family protein 0.0029 0.0089 0.0089
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0112 0.1632 0.1632
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0114 0.1668 0.1668
Echinococcus multilocularis receptor type guanylyl cyclase 0.0112 0.1632 0.1632
Brugia malayi SH2 domain containing protein 0.0159 0.2522 0.2522
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0271 0.4616 0.4616
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0114 0.1668 0.1668
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0162 0.2584 0.3206
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0112 0.1632 0.1632
Loa Loa (eye worm) TK/FER protein kinase 0.0271 0.4616 0.4568
Loa Loa (eye worm) TK/FER protein kinase 0.0271 0.4616 0.4568
Echinococcus multilocularis c src tyrosine kinase 0.0271 0.4616 0.4616
Leishmania major heat shock protein 83-1 0.0558 1 1
Echinococcus multilocularis 0.0159 0.2522 0.2522
Schistosoma mansoni suppressor of cytokine signaling 0.0159 0.2522 0.2522
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0271 0.4616 0.4616
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0271 0.4616 0.4616
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) TK/ALK protein kinase 0.0112 0.1632 0.1557
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) endoplasmin 0.0558 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Mycobacterium tuberculosis Probable hydrolase 0.0029 0.0089 0.0113
Loa Loa (eye worm) TK/FER protein kinase 0.0271 0.4616 0.4568
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0112 0.1632 0.1632
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0029 0.0089 0.0113
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0114 0.1668 0.1668
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) TK protein kinase 0.0112 0.1632 0.1557
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0114 0.1668 0.212
Echinococcus granulosus kinase suppressor of Ras 1 0.0112 0.1632 0.1632
Echinococcus granulosus heat shock protein 90 0.0558 1 1
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Giardia lamblia Kinase, NEK 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Onchocerca volvulus 0.0159 0.2522 0.5373
Brugia malayi heat shock protein 90 0.0558 1 1
Entamoeba histolytica receptor protein kinase, putative 0.0112 0.1632 0.1353
Echinococcus multilocularis epidermal growth factor receptor 0.0112 0.1632 0.1632
Plasmodium falciparum heat shock protein 90 0.0558 1 1
Onchocerca volvulus 0.0112 0.1632 0.3408
Brugia malayi Hsp90 protein 0.0228 0.3824 0.3824
Trichomonas vaginalis endoplasmin, putative 0.0342 0.5955 0.5955
Echinococcus granulosus protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0112 0.1632 0.1557
Plasmodium falciparum tyrosine kinase-like protein 0.0112 0.1632 0.1632
Schistosoma mansoni hypothetical protein 0.0042 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.006 0.0668 0.0668
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0029 0.0089 0.0089
Schistosoma mansoni heat shock protein 0.0558 1 1
Schistosoma mansoni heat shock protein 0.0228 0.3824 0.3824
Loa Loa (eye worm) hypothetical protein 0.0039 0.0271 0.0184
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0159 0.2522 0.2522
Brugia malayi MH2 domain containing protein 0.0305 0.5257 0.5257
Giardia lamblia Grp94/Hsp90 0.0444 0.7869 0.7869
Echinococcus granulosus tyrosine protein kinase 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Loa Loa (eye worm) glutathione reductase 0.0071 0.0873 0.0791
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0112 0.1632 0.1557
Leishmania major heat shock protein 83-1 0.0558 1 1
Leishmania major heat shock protein 83-1 0.0558 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.1632 0.1632
Echinococcus multilocularis epidermal growth factor receptor 0.0112 0.1632 0.1632
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0861 0.0861
Plasmodium vivax tyrosine kinase-like protein, putative 0.0112 0.1632 0.1632
Trypanosoma brucei DNA topoisomerase ii 0.0114 0.1668 0.1668
Toxoplasma gondii heat shock protein 75, putative 0.0228 0.3824 0.3824
Trypanosoma brucei developmentally regulated phosphoprotein 0.0114 0.1668 0.1668
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trypanosoma brucei heat shock protein, putative 0.0558 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Schistosoma mansoni tyrosine kinase 0.0271 0.4616 0.4616
Brugia malayi Protein kinase domain containing protein 0.0271 0.4616 0.4616
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Echinococcus multilocularis tyrosine protein kinase shark 0.0271 0.4616 0.4616
Echinococcus granulosus SH2 motif 0.0159 0.2522 0.2522
Echinococcus granulosus tyrosine protein kinase Fyn 0.0271 0.4616 0.4616
Mycobacterium ulcerans DNA gyrase subunit B 0.0114 0.1668 0.212
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.013 0.1981 0.1909
Schistosoma mansoni endoplasmin 0.0558 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Leishmania major heat shock protein 83-1 0.0558 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.1632 0.1632
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0114 0.1668 0.1668
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Mycobacterium tuberculosis Probable esterase LipL 0.0029 0.0089 0.0113
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0159 0.2522 0.2455
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0114 0.1668 0.212
Schistosoma mansoni SH2A 0.0159 0.2522 0.2522
Brugia malayi Receptor family ligand binding region containing protein 0.0112 0.1632 0.1632
Mycobacterium tuberculosis Probable reductase 0.0162 0.2584 0.3283
Echinococcus granulosus tyrosine protein kinase HCK 0.0112 0.1632 0.1632
Mycobacterium tuberculosis Probable dehydrogenase 0.0162 0.2584 0.3283
Echinococcus granulosus tyrosine protein kinase csk 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Loa Loa (eye worm) RGC/RGC protein kinase 0.0112 0.1632 0.1557
Echinococcus granulosus tyrosine protein kinase Src64B 0.0271 0.4616 0.4616
Mycobacterium ulcerans esterase/lipase LipP 0.0029 0.0089 0.0113
Trypanosoma brucei heat shock protein 90, putative 0.0558 1 1
Mycobacterium leprae Probable two component sensor kinase MprB 0.0114 0.1668 0.203
Schistosoma mansoni hypothetical protein 0.006 0.0668 0.0668
Echinococcus granulosus natriuretic peptide receptor 1 0.0112 0.1632 0.1632
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0114 0.1668 0.3488
Entamoeba histolytica serine/threonine kinase, putative 0.0112 0.1632 0.1353
Onchocerca volvulus 0.0112 0.1632 0.3408
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0228 0.3824 0.8251
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0114 0.1668 0.212
Schistosoma mansoni tensin-related 0.0159 0.2522 0.2522
Trichomonas vaginalis protein tyrosine kinase, putative 0.0112 0.1632 0.1632
Echinococcus granulosus signal transduction protein lnk realted 0.0159 0.2522 0.2522
Echinococcus multilocularis tyrosine protein kinase Srms 0.0271 0.4616 0.4616
Leishmania major DNA topoisomerase ii 0.0114 0.1668 0.1668
Giardia lamblia Kinase, NEK 0.0112 0.1632 0.1632
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0112 0.1632 0.1353
Loa Loa (eye worm) TK/EPH protein kinase 0.0112 0.1632 0.1557
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Onchocerca volvulus 0.0112 0.1632 0.3408
Brugia malayi SH2 domain containing protein 0.0271 0.4616 0.4616
Trichomonas vaginalis heat shock protein, putative 0.0444 0.7869 0.7869
Chlamydia trachomatis DNA gyrase subunit B 0.0114 0.1668 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Schistosoma mansoni hypothetical protein 0.006 0.0668 0.0668
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Onchocerca volvulus 0.0112 0.1632 0.3408
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0114 0.1668 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0188 0.3062 0.3891
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis N chimaerin 0.0159 0.2522 0.2522
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0114 0.1668 0.1668
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Mycobacterium tuberculosis Probable oxidoreductase 0.018 0.2923 0.3715
Loa Loa (eye worm) TK protein kinase 0.0271 0.4616 0.4568
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0114 0.1668 0.1668
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0114 0.1668 0.212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Echinococcus granulosus growth factor receptor bound protein 2 0.0159 0.2522 0.2522
Loa Loa (eye worm) TK protein kinase 0.0112 0.1632 0.1557
Echinococcus multilocularis tensin 0.0159 0.2522 0.2522
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0271 0.4616 0.4616
Leishmania major heat shock protein, putative 0.0228 0.3824 0.3824
Echinococcus multilocularis heat shock protein 90 0.0558 1 1
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Loa Loa (eye worm) TK/CSK protein kinase 0.0112 0.1632 0.1557
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0029 0.0089 0.0113
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0159 0.2522 0.2522
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0112 0.1632 0.1632
Brugia malayi kinase, mitochondrial precursor 0.0114 0.1668 0.1668
Plasmodium falciparum heat shock protein 90, putative 0.0228 0.3824 0.3824
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0159 0.2522 0.2522
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Onchocerca volvulus 0.0271 0.4616 1
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Trichomonas vaginalis AGC family protein kinase 0.0112 0.1632 0.1632
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0114 0.1668 0.3488
Schistosoma mansoni tensin-related 0.0159 0.2522 0.2522
Trichomonas vaginalis heat shock protein, putative 0.0558 1 1
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Plasmodium falciparum protein kinase, putative 0.0112 0.1632 0.1632
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0114 0.1668 0.212
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0112 0.1632 0.1632
Trypanosoma cruzi DNA topoisomerase II, putative 0.0114 0.1668 0.1668
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0114 0.1668 0.203
Trypanosoma brucei trypanothione reductase 0.0071 0.0873 0.0873
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0112 0.1632 0.1632
Leishmania major hypothetical protein, conserved 0.0029 0.0089 0.0089
Entamoeba histolytica serine/threonine kinase, putative 0.0112 0.1632 0.1353
Trypanosoma cruzi Heat shock protein 83, putative 0.0558 1 1
Echinococcus multilocularis protein kinase 0.0112 0.1632 0.1632
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0114 0.1668 0.1668
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Loa Loa (eye worm) TK/ACK protein kinase 0.0112 0.1632 0.1557
Echinococcus multilocularis SH2 motif 0.0159 0.2522 0.2522
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Echinococcus granulosus tyrosine protein kinase csk 0.0112 0.1632 0.1632
Brugia malayi hypothetical protein 0.0159 0.2522 0.2522
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Echinococcus multilocularis tyrosine protein kinase Blk 0.0271 0.4616 0.4616
Loa Loa (eye worm) TK/INSR protein kinase 0.0112 0.1632 0.1557
Echinococcus granulosus tyrosine kinase 0.0112 0.1632 0.1632
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0444 0.7869 1
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0112 0.1632 0.1632
Echinococcus multilocularis signal transduction protein lnk realted 0.0159 0.2522 0.2522
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0114 0.1668 0.1668
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Brugia malayi SRC-1 0.0271 0.4616 0.4616
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Giardia lamblia Heat shock protein HSP 90-alpha 0.0558 1 1
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0112 0.1632 0.1632
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0444 0.7869 0.7869
Schistosoma mansoni ephrin receptor 0.0112 0.1632 0.1632
Leishmania major heat shock protein 83-1 0.0558 1 1
Entamoeba histolytica heat shock protein 90, putative 0.0558 1 1
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0159 0.2522 0.2522
Toxoplasma gondii DNA topoisomerase 2, putative 0.0114 0.1668 0.1668
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.1632 0.1557
Schistosoma mansoni tyrosine kinase 0.0271 0.4616 0.4616
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0159 0.2522 0.2522
Trichomonas vaginalis heat shock protein, putative 0.0444 0.7869 0.7869
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0114 0.1668 0.212
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0159 0.2522 0.2522
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus granulosus SH2 domain containing adapter protein F 0.0159 0.2522 0.2522
Mycobacterium tuberculosis Possible two component sensor kinase 0.0114 0.1668 0.212
Entamoeba histolytica serine/threonine kinase, putative 0.0112 0.1632 0.1353
Schistosoma mansoni hypothetical protein 0.006 0.0668 0.0668
Brugia malayi Calcitonin receptor-like protein seb-1 0.019 0.3112 0.3112
Onchocerca volvulus 0.0271 0.4616 1
Loa Loa (eye worm) TK/FAK protein kinase 0.0112 0.1632 0.1557
Onchocerca volvulus 0.0271 0.4616 1
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0159 0.2522 0.2522
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Leishmania major cathepsin L-like protease 0.0071 0.0861 0.0861
Brugia malayi hypothetical protein 0.0025 0.0011 0.0011
Leishmania major cathepsin L-like protease 0.0071 0.0861 0.0861
Trypanosoma cruzi heat shock protein 90, putative 0.0558 1 1
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1857 0.1857
Echinococcus granulosus NCK adaptor protein 0.0159 0.2522 0.2522
Brugia malayi STAT protein, DNA binding domain containing protein 0.0159 0.2522 0.2522
Trypanosoma brucei heat shock protein, putative 0.0558 1 1
Echinococcus granulosus suppressor of cytokine signaling 6 0.0159 0.2522 0.2522
Brugia malayi tRNA modification GTPase TrmE family protein 0.0159 0.2522 0.2522
Mycobacterium ulcerans putative regultory protein 0.0114 0.1668 0.212
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0271 0.4616 0.4616
Echinococcus multilocularis ephrin type A receptor 4 A 0.0112 0.1632 0.1632
Onchocerca volvulus 0.0046 0.0391 0.0667
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0112 0.1632 0.1632
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0112 0.1632 0.1632
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0112 0.1632 0.1557
Entamoeba histolytica serine/threonine kinase, putative 0.0112 0.1632 0.1353
Schistosoma mansoni suppressor of cytokine signaling 0.0159 0.2522 0.2522
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0114 0.1668 0.212
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.018 0.2923 0.3643
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus granulosus expressed conserved protein 0.0159 0.2522 0.2522
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Echinococcus multilocularis NCK adaptor protein 0.0159 0.2522 0.2522
Brugia malayi ephrin receptor 1 precursor 0.0112 0.1632 0.1632
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0114 0.1668 0.1668
Entamoeba histolytica tyrosin kinase, putative 0.0112 0.1632 0.1353
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0271 0.4616 0.4616
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0114 0.1668 0.212
Echinococcus multilocularis SH2 motif 0.0159 0.2522 0.2522
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0112 0.1632 0.1632
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0412 0.0412
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Giardia lamblia Kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus granulosus epidermal growth factor receptor 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Onchocerca volvulus 0.0271 0.4616 1
Entamoeba histolytica serine/threonine kinase, putative 0.0112 0.1632 0.1353
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0271 0.4616 0.4616
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Trypanosoma brucei heat shock protein, putative 0.0558 1 1
Echinococcus multilocularis activin receptor type 0.0112 0.1632 0.1632
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0114 0.1668 0.212
Brugia malayi Protein kinase domain containing protein 0.0271 0.4616 0.4616
Schistosoma mansoni tensin 0.0159 0.2522 0.2522
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0112 0.1632 0.1632
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Brugia malayi Variant SH3 domain containing protein 0.0159 0.2522 0.2522
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0114 0.1668 0.1668
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Echinococcus granulosus tyrosine protein kinase Srms 0.0271 0.4616 0.4616
Brugia malayi SH2 domain containing protein 0.0159 0.2522 0.2522
Trypanosoma cruzi protein kinase, putative 0.0112 0.1632 0.1632
Onchocerca volvulus 0.0112 0.1632 0.3408
Toxoplasma gondii ABC1 family protein 0.0029 0.0089 0.0089
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni protein tyrosine kinase 0.0112 0.1632 0.1632
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0114 0.1668 0.212
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0112 0.1632 0.1557
Loa Loa (eye worm) TK/FER protein kinase 0.0271 0.4616 0.4568
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0089 0.0089
Trypanosoma cruzi heat shock protein 85, putative 0.0558 1 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0271 0.4616 0.4616
Plasmodium vivax hypothetical protein, conserved 0.0114 0.1668 0.1668
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0444 0.7869 1
Schistosoma mansoni vav2 0.0159 0.2522 0.2522
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Echinococcus granulosus tyrosine protein kinase Blk 0.0271 0.4616 0.4616
Onchocerca volvulus Tyrosine kinase homolog 0.0112 0.1632 0.3408
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Plasmodium vivax heat shock protein 86, putative 0.0558 1 1
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0112 0.1632 0.1632
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.006 0.0668 0.0668
Loa Loa (eye worm) RNA binding protein 0.0124 0.1857 0.1784
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0271 0.4616 0.4616
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Schistosoma mansoni hypothetical protein 0.0159 0.2522 0.2522
Brugia malayi Raf kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Trichomonas vaginalis STE family protein kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Plasmodium vivax protein kinase, putative 0.0112 0.1632 0.1632
Loa Loa (eye worm) serine/threonine protein kinase 0.0112 0.1632 0.1557
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.006 0.0668 0.0668
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0114 0.1668 0.212
Brugia malayi RhoGAP domain containing protein 0.0159 0.2522 0.2522
Echinococcus granulosus tyrosine protein kinase ABL1 0.0271 0.4616 0.4616
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0112 0.1632 0.1353
Trichomonas vaginalis heat shock protein, putative 0.0228 0.3824 0.3824
Echinococcus granulosus raf serine:threonine protein kinase 0.0112 0.1632 0.1632
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0114 0.1668 0.212
Onchocerca volvulus 0.0159 0.2522 0.5373
Loa Loa (eye worm) protein kinase domain-containing protein 0.0112 0.1632 0.1557
Schistosoma mansoni tyrosine protein kinase 0.0112 0.1632 0.1632
Leishmania major heat shock protein 83-1 0.0558 1 1
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0114 0.1668 0.3488
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0114 0.1668 0.212
Schistosoma mansoni survival motor neuron protein 0.0047 0.0412 0.0412
Trypanosoma cruzi PAB1-binding protein , putative 0.0039 0.0271 0.0271
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Echinococcus granulosus heat shock protein 0.0558 1 1
Leishmania major cathepsin L-like protease 0.0071 0.0861 0.0861
Loa Loa (eye worm) STAT protein 0.0159 0.2522 0.2455
Echinococcus granulosus insulin receptor 0.0112 0.1632 0.1632
Echinococcus multilocularis thioredoxin glutathione reductase 0.0072 0.0881 0.0881
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0112 0.1632 0.1632
Mycobacterium ulcerans two component regulator - sensor kinase 0.0114 0.1668 0.212
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.1632 0.1557
Echinococcus granulosus receptor type guanylyl cyclase 0.0112 0.1632 0.1632
Echinococcus granulosus GPCR family 2 0.006 0.0668 0.0668
Schistosoma mansoni tensin 0.0159 0.2522 0.2522
Echinococcus granulosus tyrosine protein kinase Src42A 0.0271 0.4616 0.4616
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.1632 0.1632
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Echinococcus granulosus c src tyrosine kinase 0.0271 0.4616 0.4616
Echinococcus multilocularis protein tyrosine kinase 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Trypanosoma brucei heat shock protein, putative 0.0558 1 1
Brugia malayi SH2 domain containing protein 0.0159 0.2522 0.2522
Brugia malayi Furin-like cysteine rich region family protein 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Plasmodium vivax tyrosine kinase-like protein, putative 0.0112 0.1632 0.1632
Echinococcus multilocularis SH2 domain containing protein 7 0.0159 0.2522 0.2522
Loa Loa (eye worm) TK protein kinase 0.0112 0.1632 0.1557
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Echinococcus multilocularis heat shock protein 90 0.0444 0.7869 0.7869
Schistosoma mansoni growth factor receptor-bound protein 0.0159 0.2522 0.2522
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0112 0.1632 0.1632
Schistosoma mansoni endoplasmin 0.0558 1 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0271 0.4616 0.4616
Echinococcus multilocularis tyrosine protein kinase csk 0.0112 0.1632 0.1632
Onchocerca volvulus 0.0112 0.1632 0.3408
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0162 0.2584 0.3283
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Echinococcus multilocularis tyrosine kinase 0.0271 0.4616 0.4616
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Echinococcus granulosus endoplasmin 0.0444 0.7869 0.7869
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.1632 0.1632
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.1632 0.1557
Brugia malayi Variant SH3 domain containing protein 0.0159 0.2522 0.2522
Loa Loa (eye worm) SRC-1 0.0271 0.4616 0.4568
Leishmania major heat shock protein 83-1 0.0558 1 1
Echinococcus multilocularis protein KINase family member (kin 25) 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Loa Loa (eye worm) TOPoisomerase family member 0.0114 0.1668 0.1593
Loa Loa (eye worm) thioredoxin reductase 0.0071 0.0873 0.0791
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0114 0.1668 0.1668
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0228 0.3824 0.3824
Trypanosoma brucei heat shock protein, putative 0.0558 1 1
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0228 0.3824 0.3618
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Loa Loa (eye worm) TK/FER protein kinase 0.0271 0.4616 0.4568
Loa Loa (eye worm) heat shock protein 90 0.0558 1 1
Trichomonas vaginalis protein kinase atn1, putative 0.0112 0.1632 0.1632
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.0603 0.0518
Echinococcus multilocularis raf serine:threonine protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) latrophilin receptor protein 2 0.006 0.0668 0.0585
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.3824 0.3824
Echinococcus granulosus tensin 0.0159 0.2522 0.2522
Toxoplasma gondii heat shock protein 90, putative 0.0558 1 1
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Schistosoma mansoni hypothetical protein 0.0112 0.1632 0.1632
Plasmodium falciparum ataxin-2 like protein, putative 0.0039 0.0271 0.0271
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0159 0.2522 0.2522
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Schistosoma mansoni signal transduction protein lnk-related 0.0159 0.2522 0.2522
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Onchocerca volvulus 0.0112 0.1632 0.3408
Brugia malayi Sex muscle abnormal protein 5 0.0159 0.2522 0.2522
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0159 0.2522 0.2522
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0112 0.1632 0.1632
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Trypanosoma cruzi heat shock protein 85, putative 0.0558 1 1
Leishmania major protein kinase, putative 0.0112 0.1632 0.1632
Echinococcus granulosus tyrosine protein kinase Lyn 0.0271 0.4616 0.4616
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis heat shock protein 70 0.0112 0.1632 0.1632
Trypanosoma cruzi heat shock protein 85, putative 0.0444 0.7869 0.7869
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Echinococcus granulosus beta LACTamase domain containing family member 0.0029 0.0089 0.0089
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0114 0.1668 0.1668
Onchocerca volvulus 0.0159 0.2522 0.5373
Leishmania major heat shock protein 83-1 0.0558 1 1
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Schistosoma mansoni ephrin receptor 0.0112 0.1632 0.1632
Entamoeba histolytica DNA topoisomerase II, putative 0.0114 0.1668 0.139
Mycobacterium tuberculosis Probable lipase LipD 0.0029 0.0089 0.0113
Brugia malayi Variant SH3 domain containing protein 0.0159 0.2522 0.2522
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0159 0.2522 0.2522
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0089 0.0089
Toxoplasma gondii LsmAD domain-containing protein 0.0039 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.1632 0.1632
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0159 0.2522 0.2522
Echinococcus granulosus SH2 domain containing protein 7 0.0159 0.2522 0.2522
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Entamoeba histolytica serine/threonine kinase, putative 0.0112 0.1632 0.1353
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0029 0.0089 0.0089
Loa Loa (eye worm) RGC/RGC protein kinase 0.0112 0.1632 0.1557
Brugia malayi Thioredoxin reductase 0.0071 0.0873 0.0873
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0114 0.1668 0.212
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0112 0.1632 0.1557
Brugia malayi SH2 domain containing protein 0.0159 0.2522 0.2522
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0323 0.0323
Plasmodium vivax heat shock protein 90, putative 0.0228 0.3824 0.3824
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0114 0.1668 0.1593
Leishmania major hypothetical protein, conserved 0.0039 0.0271 0.0271
Echinococcus multilocularis GPCR, family 2 0.006 0.0668 0.0668
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0112 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Schistosoma mansoni protein kinase 0.0112 0.1632 0.1632
Trypanosoma brucei PAB1-binding protein , putative 0.0039 0.0271 0.0271
Loa Loa (eye worm) TK/ABL protein kinase 0.0271 0.4616 0.4568
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Echinococcus multilocularis heat shock protein 0.0558 1 1
Giardia lamblia Pms1-like protein 0.0114 0.1668 0.1668
Trypanosoma cruzi heat shock protein, putative 0.0228 0.3824 0.3824
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0112 0.1632 0.1632
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Echinococcus multilocularis tumor protein p63 0.0311 0.5371 0.5371
Onchocerca volvulus 0.0159 0.2522 0.5373
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni adapter molecule crk 0.0159 0.2522 0.2522
Echinococcus granulosus tyrosine protein kinase Fyn 0.0271 0.4616 0.4616
Echinococcus granulosus tyrosine protein kinase shark 0.0271 0.4616 0.4616
Trichomonas vaginalis DNA topoisomerase II, putative 0.0114 0.1668 0.1668
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0112 0.1632 0.1632
Echinococcus granulosus SHC transforming protein 3 0.0159 0.2522 0.2522
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0112 0.1632 0.1632
Loa Loa (eye worm) heat shock protein 75 0.0228 0.3824 0.3769
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Schistosoma mansoni nck2/grb4 0.0159 0.2522 0.2522
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Entamoeba histolytica receptor protein kinase, putative 0.0112 0.1632 0.1353
Plasmodium vivax DNA topoisomerase II, putative 0.0114 0.1668 0.1668
Schistosoma mansoni tyrosine kinase 0.0271 0.4616 0.4616
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trypanosoma cruzi heat shock protein 90, putative 0.0329 0.5713 0.5713
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0114 0.1668 0.203
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0323 0.0323
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0112 0.1632 0.1632
Trypanosoma brucei protein kinase, putative 0.0112 0.1632 0.1632
Schistosoma mansoni growth factor receptor-bound protein 0.0159 0.2522 0.2522
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0029 0.0089 0.0113
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0112 0.1632 0.3408
Brugia malayi beta-lactamase 0.0029 0.0089 0.0089
Loa Loa (eye worm) TK/DDR protein kinase 0.0112 0.1632 0.1557
Loa Loa (eye worm) TK protein kinase 0.0112 0.1632 0.1557
Echinococcus multilocularis tyrosine protein kinase csk 0.0112 0.1632 0.1632
Trypanosoma brucei Pseudokinase, putative 0.0112 0.1632 0.1632
Plasmodium falciparum glutathione reductase 0.0071 0.0873 0.0873
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1857 0.1857
Leishmania major developmentally regulated phosphoprotein-like protein 0.0114 0.1668 0.1668
Brugia malayi RNA recognition motif domain containing protein 0.0124 0.1857 0.1857
Leishmania major mitochondrial DNA topoisomerase II 0.0114 0.1668 0.1668
Entamoeba histolytica SH2 domain containing protein 0.0159 0.2522 0.2272
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Plasmodium falciparum heat shock protein 90, putative 0.0228 0.3824 0.3824
Leishmania major hypothetical protein, conserved 0.0114 0.1668 0.1668
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Echinococcus granulosus thioredoxin glutathione reductase 0.0072 0.0881 0.0881
Brugia malayi Protein kinase domain containing protein 0.0271 0.4616 0.4616
Echinococcus granulosus tar DNA binding protein 0.0124 0.1857 0.1857
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.018 0.2923 0.3715
Brugia malayi SH2 domain containing protein 0.0159 0.2522 0.2522
Echinococcus granulosus retinal guanylyl cyclase 2 0.0112 0.1632 0.1632
Leishmania major heat shock protein 83-1 0.0558 1 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0112 0.1632 0.1632
Schistosoma mansoni serine/threonine RGC 0.0112 0.1632 0.1632
Toxoplasma gondii protein kinase domain-containing protein 0.0112 0.1632 0.1632
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0162 0.2584 0.3283
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0112 0.1632 0.1632
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0159 0.2522 0.2455
Onchocerca volvulus 0.0047 0.0412 0.0713
Entamoeba histolytica hypothetical protein, conserved 0.0112 0.1632 0.1353
Loa Loa (eye worm) hypothetical protein 0.019 0.3112 0.305
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Mycobacterium ulcerans lipase LipD 0.0029 0.0089 0.0113
Entamoeba histolytica hypothetical protein 0.0112 0.1632 0.1353
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0159 0.2522 0.2272
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Brugia malayi hypothetical protein 0.0042 0.0323 0.0323
Echinococcus granulosus suppressor of cytokine signaling 7 0.0159 0.2522 0.2522
Schistosoma mansoni DNA topoisomerase II 0.0114 0.1668 0.1668
Toxoplasma gondii protein kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Brugia malayi Probable DNA topoisomerase II 0.0114 0.1668 0.1668
Echinococcus multilocularis tyrosine protein kinase csk 0.0112 0.1632 0.1632
Loa Loa (eye worm) RGC/RGC protein kinase 0.0112 0.1632 0.1557
Trichomonas vaginalis esterase, putative 0.0029 0.0089 0.0089
Plasmodium vivax thioredoxin reductase, putative 0.0071 0.0873 0.0873
Echinococcus granulosus fibroblast growth factor receptor 4 0.0112 0.1632 0.1632
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0112 0.1632 0.1557
Plasmodium vivax heat shock protein, putative 0.0228 0.3824 0.3824
Plasmodium vivax ataxin-2 like protein, putative 0.0039 0.0271 0.0271
Echinococcus multilocularis tyrosine kinase 0.0112 0.1632 0.1632
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0162 0.2584 0.3283
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Schistosoma mansoni hypothetical protein 0.006 0.0668 0.0668
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0112 0.1632 0.1632
Loa Loa (eye worm) MH2 domain-containing protein 0.0305 0.5257 0.5214
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0112 0.1632 0.1632
Brugia malayi Latrophilin receptor protein 2 0.006 0.0668 0.0668
Loa Loa (eye worm) hypothetical protein 0.0112 0.1632 0.1557
Brugia malayi Guanylyl cyclase protein 23 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0114 0.1668 0.1668
Loa Loa (eye worm) hypothetical protein 0.0228 0.3824 0.3768
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0112 0.1632 0.1353
Brugia malayi SH2 domain containing protein 0.0159 0.2522 0.2522
Schistosoma mansoni hypothetical protein 0.0047 0.0412 0.0412
Loa Loa (eye worm) RGC/RGC protein kinase 0.0112 0.1632 0.1557
Loa Loa (eye worm) TK protein kinase 0.0112 0.1632 0.1557
Trichomonas vaginalis receptor histidine kinase, putative 0.0114 0.1668 0.1668
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.006 0.0668 0.0668
Plasmodium vivax glutathione reductase, putative 0.0071 0.0873 0.0873
Entamoeba histolytica tyrosin kinase, putative 0.0112 0.1632 0.1353
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0112 0.1632 0.1632
Trypanosoma brucei heat shock protein 90, putative 0.0558 1 1
Plasmodium falciparum DNA gyrase subunit B 0.0114 0.1668 0.1668
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0228 0.3824 0.3824
Loa Loa (eye worm) transcription factor SMAD2 0.0305 0.5257 0.5214
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0071 0.0873 0.1109
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.006 0.0668 0.0585
Plasmodium falciparum protein kinase, putative 0.0112 0.1632 0.1632
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0112 0.1632 0.3408
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Brugia malayi hypothetical protein 0.0228 0.3824 0.3824
Trichomonas vaginalis heat shock protein, putative 0.0444 0.7869 0.7869
Echinococcus multilocularis tyrosine protein kinase HCK 0.0112 0.1632 0.1632
Plasmodium falciparum ataxin-2 like protein, putative 0.0039 0.0271 0.0271
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.1632 0.1557
Entamoeba histolytica tyrosine kinase, putative 0.0112 0.1632 0.1353
Trypanosoma brucei heat shock protein 84, putative 0.0228 0.3824 0.3824
Trypanosoma cruzi trypanothione reductase, putative 0.0071 0.0873 0.0873
Leishmania major heat shock protein 83-1 0.0558 1 1
Entamoeba histolytica cysteine surface protein, putative 0.0112 0.1632 0.1353
Toxoplasma gondii Hsp90 domain-containing protein 0.0228 0.3824 0.3824
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0112 0.1632 0.1632
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0861 0.0861
Onchocerca volvulus 0.0271 0.4616 1
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.1632 0.1557
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.1632 0.1353
Onchocerca volvulus 0.0271 0.4616 1
Entamoeba histolytica heat shock protein 90, putative 0.0558 1 1
Echinococcus granulosus tyrosine protein kinase csk 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0112 0.1632 0.1632
Echinococcus multilocularis growth factor receptor bound protein 2 0.0159 0.2522 0.2522
Schistosoma mansoni tyrosine kinase 0.0112 0.1632 0.1632
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0112 0.1632 0.1353
Echinococcus granulosus N chimaerin 0.0159 0.2522 0.2522
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0089 0.0089
Echinococcus granulosus activated cdc42 kinase 1 0.0112 0.1632 0.1632
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Schistosoma mansoni tyrosine kinase 0.0271 0.4616 0.4616
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0114 0.1668 0.212
Entamoeba histolytica protein kinase, putative 0.0112 0.1632 0.1353
Mycobacterium tuberculosis Conserved protein 0.0029 0.0089 0.0113
Trypanosoma brucei Flagellum attachment zone protein 20 0.0112 0.1632 0.1632
Toxoplasma gondii heat shock protein HSP90 0.0558 1 1
Brugia malayi glutathione reductase 0.0071 0.0873 0.0873
Brugia malayi C-terminal src kinase protein 1 0.0112 0.1632 0.1632
Trichomonas vaginalis TKL family protein kinase 0.0112 0.1632 0.1632
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0323 0.0323
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0114 0.1668 0.1668
Loa Loa (eye worm) hypothetical protein 0.0159 0.2522 0.2455
Brugia malayi protein-tyrosine kinase 0.0271 0.4616 0.4616
Plasmodium falciparum tyrosine kinase-like protein 0.0112 0.1632 0.1632
Brugia malayi Protein kinase domain containing protein 0.0112 0.1632 0.1632
Onchocerca volvulus 0.0112 0.1632 0.3408
Leishmania major hypothetical protein, conserved 0.0112 0.1632 0.1632
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0114 0.1668 0.212
Trypanosoma brucei heat shock protein, putative 0.0558 1 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0159 0.2522 0.2522
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0159 0.2522 0.2455
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0578 0.0578

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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