Detailed information for compound 1663750

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2422.9 | Formula: C110H216N6O50
  • H donors: 4 H acceptors: 4 LogP: -4.56 Rotable bonds: 154
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCNc1nc(C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)c(nc1C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)NCCC
  • InChi: 1S/C110H216N6O50/c1-5-7-111-107-105(109(117)113-9-11-121-17-19-125-25-27-129-33-35-133-41-43-137-49-51-141-57-59-145-65-67-149-73-75-153-81-83-157-89-91-161-97-99-165-103-101-163-95-93-159-87-85-155-79-77-151-71-69-147-63-61-143-55-53-139-47-45-135-39-37-131-31-29-127-23-21-123-15-13-119-3)116-108(112-8-6-2)106(115-107)110(118)114-10-12-122-18-20-126-26-28-130-34-36-134-42-44-138-50-52-142-58-60-146-66-68-150-74-76-154-82-84-158-90-92-162-98-100-166-104-102-164-96-94-160-88-86-156-80-78-152-72-70-148-64-62-144-56-54-140-48-46-136-40-38-132-32-30-128-24-22-124-16-14-120-4/h5-104H2,1-4H3,(H,111,115)(H,112,116)(H,113,117)(H,114,118)
  • InChiKey: CNEOAIUAGNAMQB-UHFFFAOYSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0047 0.0257 0.0257
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0033 0.0152 0.0152
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0595 0.0822
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0029 0.0122 0.0122
Echinococcus granulosus neuropeptide receptor 0.0029 0.0122 0.0168
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0268 0.037
Onchocerca volvulus DNA ligase 3 homolog 0.0016 0.0028 0.0039
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0148 0.0148
Schistosoma mansoni neuropeptide receptor 0.0029 0.0122 0.0167
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0023
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0033 0.0148 0.0204
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0016 0.0023 0.5
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0016 0.0028 0.0005
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0088 0.2785
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Brugia malayi hypothetical protein 0.0016 0.0023 0.0023
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0025 0.0092 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0148 0.1001 0.1381
Loa Loa (eye worm) hypothetical protein 0.0325 0.2316 0.2316
Toxoplasma gondii calcium binding egf domain-containing protein 0.0033 0.0152 0.1291
Toxoplasma gondii kringle domain-containing protein 0.0044 0.0231 0.2074
Onchocerca volvulus 0.0025 0.0092 0.0127
Loa Loa (eye worm) hypothetical protein 0.0033 0.0148 0.0148
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0079 0.0489 0.0467
Brugia malayi hypothetical protein 0.0029 0.0122 0.0122
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni egf-like domain protein 0.0033 0.0152 0.021
Echinococcus multilocularis snurportin 1 0.0323 0.2303 0.318
Echinococcus granulosus G protein coupled receptor 139 0.0029 0.0122 0.0168
Trypanosoma brucei DNA repair protein, putative 0.0016 0.0028 0.0005
Echinococcus multilocularis G-protein coupled receptor, putative 0.0029 0.0122 0.0168
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0148 0.1001 0.1381
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0323 0.2303 0.2303
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0122 0.0168
Echinococcus multilocularis orexin receptor type 2 0.0029 0.0122 0.0168
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0148 0.1001 0.1001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0595 0.0821
Leishmania major C-8 sterol isomerase-like protein 0.1361 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0122 0.0168
Onchocerca volvulus 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Plasmodium vivax importin-beta 2, putative 0.003 0.013 0.4598
Brugia malayi Tnks protein 0.0074 0.0455 0.0455
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0071 1
Schistosoma mansoni biogenic amine receptor 0.0029 0.0122 0.0167
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0029 0.0122 0.0122
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0122 0.0122
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.009 0.0067
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0122 0.0168
Echinococcus granulosus g protein coupled receptor 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0029 0.0122 0.0167
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0033 0.0148 0.0203
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0092 0.0126
Echinococcus multilocularis tankyrase 0.0075 0.0461 0.0636
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0071 0.2067
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Brugia malayi WGR domain containing protein 0.0135 0.091 0.091
Onchocerca volvulus 0.0044 0.0231 0.0319
Echinococcus multilocularis G protein coupled receptor 139 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0152 0.0152
Echinococcus multilocularis fibrillin 1 0.0033 0.0152 0.021
Loa Loa (eye worm) TK/ROR protein kinase 0.0044 0.0231 0.0231
Echinococcus granulosus allatostatin A receptor 0.0029 0.0122 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0122 0.0167
Entamoeba histolytica hypothetical protein 0.0019 0.0045 0.0246
Echinococcus granulosus poly (ADP ribose) polymerase 0.0039 0.0196 0.0271
Loa Loa (eye worm) hypothetical protein 0.0033 0.0148 0.0148
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0122 0.0167
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0079 0.0489 0.0675
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Entamoeba histolytica Ran family GTPase 0.0022 0.0071 0.0546
Schistosoma mansoni ran 0.0022 0.0071 0.0097
Echinococcus granulosus Tolloid protein 1 0.0033 0.0152 0.021
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0029 0.0122 0.0168
Brugia malayi G protein-coupled receptor F59B2.13 0.0029 0.0122 0.0122
Plasmodium falciparum amino acid transporter, putative 0.0025 0.0092 0.2949
Brugia malayi neuropeptide F receptor 0.0029 0.0122 0.0122
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0122 0.0168
Schistosoma mansoni importin beta-1 0.003 0.013 0.0179
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0029 0.0122 0.0122
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0122 0.0167
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0122 0.0167
Echinococcus granulosus g-protein coupled receptor 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0092
Echinococcus granulosus alpha 1A adrenergic receptor 0.0029 0.0122 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0122 0.0167
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0186 0.0257
Loa Loa (eye worm) hypothetical protein 0.0148 0.1001 0.1001
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0016 0.0023 0.5
Loa Loa (eye worm) solute carrier family 6 member 4 0.0148 0.1001 0.1001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.0688 0.0688
Brugia malayi Trypsin-like protease protein 5 0.0033 0.0148 0.0148
Echinococcus granulosus snurportin 1 0.0323 0.2303 0.318
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Onchocerca volvulus 0.0033 0.0148 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0122 0.0167
Schistosoma mansoni hypothetical protein 0.0049 0.0268 0.0369
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0092 0.0092
Brugia malayi Fibulin-1 precursor 0.0033 0.0152 0.0152
Brugia malayi Trypsin family protein 0.0033 0.0148 0.0148
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0033 0.0148 0.0203
Entamoeba histolytica hypothetical protein 0.0038 0.0186 0.184
Brugia malayi Serotonin receptor 0.0432 0.3111 0.3111
Echinococcus multilocularis sex peptide receptor 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.009 0.2851
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0122 0.0167
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0268 0.0268
Brugia malayi hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni neuropeptide receptor 0.0029 0.0122 0.0167
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0016 0.0023 0.0000077793
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0122 0.0168
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Plasmodium falciparum plasmepsin I 0.0047 0.0257 1
Brugia malayi hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni neuropeptide receptor 0.0029 0.0122 0.0167
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0595 0.0595
Echinococcus granulosus serotonin transporter 0.0148 0.1001 0.1382
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0092 0.0127
Schistosoma mansoni ran 0.0022 0.0071 0.0097
Echinococcus granulosus vesicular acetylcholine transporter 0.0989 0.7242 1
Brugia malayi AKH receptor 0.0029 0.0122 0.0122
Echinococcus granulosus enteropeptidase 0.0033 0.0148 0.0204
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0029 0.0122 0.0168
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0092 0.0092
Brugia malayi putative neuropeptide receptor 0.0029 0.0122 0.0122
Echinococcus multilocularis Mastin 0.0033 0.0148 0.0204
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0079 0.0489 0.0674
Echinococcus granulosus orexin receptor type 2 0.0029 0.0122 0.0168
Onchocerca volvulus 0.0029 0.0122 0.0168
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0029 0.0122 0.0167
Loa Loa (eye worm) hypothetical protein 0.0033 0.0152 0.0152
Schistosoma mansoni sodium-dependent amino acid transporter 0.0025 0.0092 0.0126
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.009 0.0067
Echinococcus multilocularis serotonin receptor 0.0029 0.0122 0.0168
Schistosoma mansoni hypothetical protein 0.0029 0.0122 0.0167
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Schistosoma mansoni biogenic amine receptor 0.0029 0.0122 0.0167
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0029 0.0122 0.0167
Echinococcus granulosus 7tm_1 domain containing protein 0.0029 0.0122 0.0168
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0122 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0933
Schistosoma mansoni opsin-like receptor 0.0029 0.0122 0.0167
Echinococcus multilocularis neuropeptide s receptor 0.0029 0.0122 0.0168
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0122 0.0167
Echinococcus multilocularis glycoprotein Antigen 5 0.0033 0.0148 0.0204
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0016 0.0023 0.0023
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0135 0.091 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Onchocerca volvulus 0.0029 0.0122 0.0168
Plasmodium falciparum plasmepsin II 0.0047 0.0257 1
Schistosoma mansoni opsin-like receptor 0.0029 0.0122 0.0167
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0122 0.0168
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0088 0.2785
Plasmodium falciparum plasmepsin VI 0.0047 0.0257 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus granulosus neuropeptide FF receptor 2 0.0029 0.0122 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0122 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0933
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0047 0.0257 0.0355
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0092 0.0127
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0122 0.0168
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0029 0.0122 0.0167
Entamoeba histolytica hypothetical protein 0.0038 0.0186 0.184
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0092 0.0092
Echinococcus multilocularis nibrin 0.0016 0.0023 0.0031
Echinococcus granulosus Mastin 0.0033 0.0148 0.0204
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0122 0.0168
Onchocerca volvulus 0.0029 0.0122 0.0168
Onchocerca volvulus 0.0029 0.0122 0.0168
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0025 0.0092 0.0127
Schistosoma mansoni hypothetical protein 0.0029 0.0122 0.0167
Echinococcus multilocularis somatostatin receptor 0.0029 0.0122 0.0168
Echinococcus multilocularis neuropeptide FF receptor 2 0.0029 0.0122 0.0168
Echinococcus multilocularis serotonin transporter 0.0148 0.1001 0.1382
Brugia malayi hypothetical protein 0.0029 0.0122 0.0122
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0025 0.0092 0.0127
Plasmodium falciparum cysteine repeat modular protein 1 0.0044 0.0231 0.8893
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus granulosus poly (ADP ribose) polymerase 0.002 0.0051 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0933
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus granulosus fmrfamide receptor 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0148 0.1001 0.1001
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0059 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1361 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.003 0.013 0.013
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0717 0.5221 0.7209
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0033 0.0148 0.0204
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0071 0.0071
Loa Loa (eye worm) trypsin family protein 0.0033 0.0148 0.0148
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Schistosoma mansoni hypothetical protein 0.0049 0.0268 0.0369
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0595 0.0822
Brugia malayi hypothetical protein 0.0033 0.0148 0.0148
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0092 0.0688
Schistosoma mansoni hypothetical protein 0.0049 0.0268 0.0369
Onchocerca volvulus 0.0325 0.2316 0.3198
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0092 0.0126
Schistosoma mansoni tankyrase 0.0075 0.0461 0.0636
Echinococcus granulosus transmembrane protease serine 3 0.0033 0.0148 0.0204
Leishmania major hypothetical protein, conserved 0.0025 0.009 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0933
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0029 0.0122 0.0122
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0016 0.0023 0.0000077793
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Brugia malayi hypothetical protein 0.0029 0.0122 0.0122
Trichomonas vaginalis ran, putative 0.0022 0.0071 0.2068
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0092 0.2949
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0047 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0044 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) TYRA-2 protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) MH2 domain-containing protein 0.0106 0.0688 0.0688
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0029 0.0122 0.0168
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0122 0.0122
Echinococcus multilocularis dro:myosuppressin receptor 0.0029 0.0122 0.0168
Brugia malayi MH2 domain containing protein 0.0106 0.0688 0.0688
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0023
Onchocerca volvulus 0.0029 0.0122 0.0168
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0122 0.0168
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0071 0.0098
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.013 0.0108
Echinococcus granulosus poly (ADP ribose) polymerase 0.002 0.0051 0.0071
Entamoeba histolytica zinc finger protein, putative 0.0019 0.0045 0.0246
Schistosoma mansoni hypothetical protein 0.0323 0.2303 0.3179
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0595 0.0595
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0038 0.019 0.0262
Loa Loa (eye worm) hypothetical protein 0.0325 0.2316 0.2316
Echinococcus multilocularis allatostatin A receptor 0.0029 0.0122 0.0168
Trichomonas vaginalis replication factor C large subunit, putative 0.0016 0.0023 0.0000077793
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0071 0.2067
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0025 0.0092 0.0127
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0268 0.037
Echinococcus granulosus 7TM GPCR rhodopsin 0.0029 0.0122 0.0168
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0088 0.0065
Onchocerca volvulus 0.0029 0.0122 0.0168
Loa Loa (eye worm) serotonin transporter b 0.0148 0.1001 0.1001
Echinococcus granulosus poly (ADP ribose) polymerase 0.002 0.0051 0.0071
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0029 0.0122 0.0167
Echinococcus granulosus replication factor c subunit 1 0.0016 0.0023 0.0031
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0148 0.1001 0.1001
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0122 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0933
Brugia malayi hypothetical protein 0.0025 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Brugia malayi sulfakinin receptor protein 0.0029 0.0122 0.0122
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0047 0.0257 0.0355
Echinococcus multilocularis vesicular acetylcholine transporter 0.0989 0.7242 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0029 0.0122 0.0122
Brugia malayi WGR domain containing protein 0.0079 0.0489 0.0489
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0033 0.0152 0.0152
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.009 0.2851
Entamoeba histolytica hypothetical protein 0.0025 0.0088 0.0735
Brugia malayi putative neuropeptide receptor NPR1 0.0029 0.0122 0.0122
Plasmodium falciparum plasmepsin IV 0.0047 0.0257 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0696 0.5065 0.5065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Brugia malayi DKFZp564C0469 protein 0.0016 0.0023 0.0023
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0151 0.1027 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0092
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0122 0.0168
Plasmodium falciparum importin beta, putative 0.003 0.013 0.4598
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.013 0.1072
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0016 0.0023 0.0000020531
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Entamoeba histolytica hypothetical protein 0.0019 0.0045 0.0246
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0029 0.0122 0.0122
Echinococcus granulosus neuropeptide receptor 0.0029 0.0122 0.0168
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0092 0.0126
Brugia malayi larval opioid receptor 0.0029 0.0122 0.0122
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0029 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0033 0.0148 0.0203
Schistosoma mansoni amine GPCR 0.0029 0.0122 0.0167
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni poly [ADP-ribose] polymerase 0.006 0.035 0.0483
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0033 0.0152 0.0152
Onchocerca volvulus 0.0029 0.0122 0.0168
Brugia malayi Kringle domain containing protein 0.0044 0.0231 0.0231
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0071 0.0098
Mycobacterium ulcerans hypothetical protein 0.0033 0.0148 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0092 0.0127
Echinococcus granulosus neuropeptide receptor A26 0.0029 0.0122 0.0168
Brugia malayi hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni chromosome transmission fidelity factor 0.0016 0.0023 0.0031
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0029 0.0122 0.0122
Brugia malayi hypothetical protein 0.0016 0.0024 0.0024
Echinococcus granulosus tankyrase 0.0075 0.0461 0.0636
Plasmodium vivax aspartyl proteinase, putative 0.0047 0.0257 1
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0122 0.0168
Loa Loa (eye worm) norepinephrine transporter 0.0148 0.1001 0.1001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0047 0.0257 0.0354
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0092 0.0688
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni DNA ligase IV 0.0016 0.0023 0.0031
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.105 0.105
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0268 0.037
Schistosoma mansoni neuropeptide f receptor 76f 0.0029 0.0122 0.0167
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0033 0.0152 0.0152
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0595 0.0822
Brugia malayi hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni cathepsin D (A01 family) 0.0047 0.0257 0.0354
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0122 0.0168
Plasmodium vivax plasmepsin IV, putative 0.0047 0.0257 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0029 0.0122 0.0168
Brugia malayi G-protein coupled receptor 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0016 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0096 0.0618 0.0618
Schistosoma mansoni topbp1 0.0016 0.0023 0.0031
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0044 0.0231 0.8893
Onchocerca volvulus 0.0033 0.0148 0.0204
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0268 0.037
Brugia malayi Importin beta-1 subunit 0.003 0.013 0.013
Brugia malayi G protein-coupled receptor 0.0029 0.0122 0.0122
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0122 0.0168
Schistosoma mansoni hypothetical protein 0.0038 0.0186 0.0256
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0595 0.0822
Schistosoma mansoni hypothetical protein 0.0033 0.0148 0.0203
Brugia malayi topoisomerase 0.0016 0.0023 0.0023
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0047 0.0257 1
Entamoeba histolytica hypothetical protein 0.0019 0.0045 0.0246
Echinococcus multilocularis g-protein coupled receptor 0.0029 0.0122 0.0168
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0071 0.0071
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0595 0.0821
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0092
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0092 0.0126
Brugia malayi hypothetical protein 0.0029 0.0122 0.0122
Echinococcus granulosus hypothetical protein 0.0029 0.0122 0.0168
Leishmania major GTP-binding protein, putative 0.0022 0.0071 0.0043
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0029 0.0122 0.0167
Toxoplasma gondii aspartyl protease ASP1 0.0047 0.0257 0.2332
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Toxoplasma gondii calcium binding egf domain-containing protein 0.0033 0.0152 0.1291
Echinococcus multilocularis serotonin receptor 0.0029 0.0122 0.0168
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0033 0.0148 0.0203
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0029 0.0122 0.0167
Brugia malayi hypothetical protein 0.0025 0.0092 0.0092
Brugia malayi Pax transcription activation domain interacting protein 0.0016 0.0023 0.0023
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0122 0.0168
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Onchocerca volvulus 0.0025 0.0092 0.0127
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Echinococcus granulosus importin subunit beta 1 0.003 0.013 0.018
Echinococcus granulosus tissue type plasminogen activator 0.0044 0.0231 0.0319
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0025 0.0092 0.0127
Schistosoma mansoni adenoreceptor 0.0029 0.0122 0.0167
Echinococcus granulosus sex peptide receptor 0.0029 0.0122 0.0168
Echinococcus granulosus WGR domain containing protein 0.0039 0.0196 0.0271
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0122 0.0167
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Onchocerca volvulus 0.0029 0.0122 0.0168
Trypanosoma brucei C-8 sterol isomerase, putative 0.1361 1 1
Brugia malayi hypothetical protein 0.0029 0.0122 0.0122
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0122 0.0168
Schistosoma mansoni biogenic amine receptor 0.0029 0.0122 0.0167
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0092 0.0127
Brugia malayi RE15519p 0.0029 0.0122 0.0122
Onchocerca volvulus 0.0029 0.0122 0.0168
Echinococcus multilocularis GPCR, family 2 0.0049 0.0268 0.037
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0122 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0933
Trypanosoma brucei poly(adp-ribose) polymerase 0.0079 0.0489 0.0467
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0092 0.0092
Onchocerca volvulus Tankyrase homolog 0.0068 0.0411 0.0568
Echinococcus multilocularis replication factor c subunit 1 0.0016 0.0023 0.0031
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0029 0.0122 0.0122
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0029 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0105 0.0688 0.0949
Brugia malayi Trypsin family protein 0.0033 0.0148 0.0148
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0029 0.0122 0.0168
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0092 0.0126
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni opsin-like receptor 0.0029 0.0122 0.0167
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Schistosoma mansoni hypothetical protein 0.0049 0.0268 0.0369
Onchocerca volvulus 0.0029 0.0122 0.0168
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0135 0.091 0.1257
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0325 0.2316 0.3198
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0325 0.2316 0.3198
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0029 0.0122 0.0168
Entamoeba histolytica hypothetical protein 0.0038 0.0186 0.184
Loa Loa (eye worm) hypothetical protein 0.0049 0.0268 0.0268
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0033 0.0152 0.0152
Echinococcus granulosus nibrin 0.0016 0.0023 0.0031
Brugia malayi Dopamine receptor protein 2 0.0029 0.0122 0.0122
Schistosoma mansoni amine GPCR 0.0029 0.0122 0.0167
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0025 0.0092 0.0127
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0122 0.0167
Loa Loa (eye worm) hypothetical protein 0.0033 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0105 0.0688 0.0688
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Onchocerca volvulus 0.0029 0.0122 0.0168
Onchocerca volvulus 0.0033 0.0148 0.0204
Echinococcus granulosus g protein coupled receptor 0.0029 0.0122 0.0168
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0033 0.0152 0.021
Brugia malayi Serotonin receptor 0.0029 0.0122 0.0122
Leishmania major importin beta-1 subunit, putative 0.0025 0.0088 0.006
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.005 0.0273 0.0273
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.009 0.0067
Schistosoma mansoni growth hormone secretagogue receptor 0.0029 0.0122 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0933
Echinococcus granulosus biogenic amine 5HT receptor 0.0757 0.5522 0.7625
Onchocerca volvulus 0.0148 0.1001 0.1382
Leishmania major hypothetical protein, conserved 0.0044 0.0231 0.0204
Echinococcus granulosus somatostatin receptor 0.0029 0.0122 0.0168
Echinococcus granulosus poly adp ribose polymerase 2 0.0079 0.0489 0.0675
Echinococcus multilocularis Tolloid protein 1 0.0033 0.0152 0.021
Echinococcus granulosus peptide allatostatin:somatostatin 0.0029 0.0122 0.0168
Brugia malayi GnHR receptor homolog 0.0029 0.0122 0.0122
Onchocerca volvulus Arrow homolog 0.0033 0.0152 0.021
Loa Loa (eye worm) hypothetical protein 0.0033 0.0152 0.0152
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0092 0.0127
Schistosoma mansoni amine GPCR 0.0029 0.0122 0.0167
Treponema pallidum sodium- and chloride- dependent transporter 0.0148 0.1001 1
Brugia malayi Protein kinase domain containing protein 0.0044 0.0231 0.0231
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.105 0.105
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0122 0.0167
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0092 0.0688
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0122 0.0168
Echinococcus granulosus glycoprotein Antigen 5 0.0033 0.0148 0.0204
Onchocerca volvulus 0.0292 0.2074 0.2864
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0092
Onchocerca volvulus 0.0029 0.0122 0.0168
Echinococcus granulosus serotonin receptor 0.0029 0.0122 0.0168
Entamoeba histolytica hypothetical protein 0.002 0.0051 0.032
Entamoeba histolytica hypothetical protein 0.0019 0.0045 0.0246
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0029 0.0122 0.0167
Loa Loa (eye worm) tnks protein 0.0069 0.0418 0.0418
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Plasmodium falciparum transporter, putative 0.0025 0.0092 0.2949
Schistosoma mansoni hypothetical protein 0.015 0.1017 0.1403
Brugia malayi Melatonin receptor type 1A 0.0029 0.0122 0.0122
Brugia malayi Dopamine receptor 0.0029 0.0122 0.0122
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0071 0.0049
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0989 0.7242 1
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0231 0.0209
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0092 0.0126
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0033 0.0148 0.0203
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.009 0.2851
Echinococcus granulosus laminin 0.0033 0.0152 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0933
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.105 0.105
Echinococcus granulosus poly ADP ribose polymerase 1 0.0135 0.091 0.1257
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0122 0.0168
Toxoplasma gondii hypothetical protein 0.0025 0.0092 0.0688
Brugia malayi follicle stimulating hormone receptor 0.0029 0.0122 0.0122
Echinococcus multilocularis enteropeptidase 0.0033 0.0148 0.0204
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0122 0.0167
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0268 0.0268
Brugia malayi G-protein coupled receptor 0.0029 0.0122 0.0122
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0122 0.0168
Brugia malayi hypothetical protein 0.0038 0.0186 0.0186
Brugia malayi Calcium binding EGF domain containing protein 0.0033 0.0152 0.0152
Schistosoma mansoni alpha-1 adrenergic receptor 0.0029 0.0122 0.0167
Loa Loa (eye worm) melatonin receptor type 1A 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus multilocularis tissue type plasminogen activator 0.0044 0.0231 0.0319
Echinococcus granulosus g protein coupled receptor 0.0029 0.0122 0.0168
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0268 0.0268
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.009 0.0665
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni cathepsin D (A01 family) 0.0047 0.0257 0.0354
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0092 0.0127
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0045 0.0933
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0595 0.0821
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0122 0.0167
Brugia malayi EGF-like domain containing protein 0.0013 0.0000071194 0.0000071194
Entamoeba histolytica hypothetical protein 0.0038 0.0186 0.184
Onchocerca volvulus 0.0016 0.0023 0.0031
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0033 0.0148 0.0203
Loa Loa (eye worm) transcription factor SMAD2 0.0106 0.0688 0.0688
Echinococcus multilocularis geminin 0.015 0.1017 0.1404
Schistosoma mansoni myosin xvIII 0.0029 0.0122 0.0167
Echinococcus multilocularis transmembrane protease serine 3 0.0033 0.0148 0.0204
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0757 0.5522 0.7625
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.009
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0047 0.0257 0.2332
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0029 0.0122 0.0168
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0092 0.0126
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0186 0.0256
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0989 0.7242 0.7242
Onchocerca volvulus Neurogenic locus notch homolog 0.0013 0.0001 0.0001
Brugia malayi RNA, U transporter 1 0.0086 0.0544 0.0544
Onchocerca volvulus 0.0029 0.0122 0.0168
Echinococcus multilocularis neuropeptide receptor A26 0.0029 0.0122 0.0168
Echinococcus multilocularis laminin 0.0033 0.0152 0.021
Trypanosoma cruzi DNA repair protein, putative 0.0016 0.0028 0.0005
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0025 0.0092 0.0092
Onchocerca volvulus 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni neuropeptide receptor 0.0029 0.0122 0.0167
Onchocerca volvulus 0.0033 0.0148 0.0204
Schistosoma mansoni hypothetical protein 0.015 0.1017 0.1403
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0122 0.0168
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0071 0.0482
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0122 0.0168
Echinococcus granulosus geminin 0.015 0.1017 0.1404
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0135 0.091 0.1256
Schistosoma mansoni hypothetical protein 0.0029 0.0122 0.0167
Plasmodium vivax amine transporter, putative 0.0025 0.0092 0.2949
Schistosoma mansoni biogenic amine (5HT) receptor 0.0757 0.5522 0.7625
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0033 0.0148 0.0204
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0092 0.0126
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0029 0.0122 0.0168
Schistosoma mansoni amine GPCR 0.0029 0.0122 0.0167
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0122 0.0167
Loa Loa (eye worm) hypothetical protein 0.0154 0.105 0.105
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0029 0.0122 0.0168
Onchocerca volvulus 0.0029 0.0122 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0122 0.0167
Schistosoma mansoni hypothetical protein 0.0029 0.0122 0.0167
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0033 0.0148 0.0203
Schistosoma mansoni vesicular acetylcholine transporter 0.0989 0.7242 1
Brugia malayi neuropeptide F receptor 0.0029 0.0122 0.0122
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0033 0.0148 0.0148
Schistosoma mansoni amine GPCR 0.0029 0.0122 0.0167
Brugia malayi vesicular acetylcholine transporter unc-17 0.0989 0.7242 0.7242
Schistosoma mansoni sodium/chloride dependent transporter 0.0025 0.0092 0.0126
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0088 0.2785
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Toxoplasma gondii hypothetical protein 0.0025 0.0092 0.0688
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Brugia malayi Trypsin family protein 0.0325 0.2316 0.2316
Brugia malayi Tachykinin-like peptides receptor 99D 0.0029 0.0122 0.0122
Onchocerca volvulus 0.0025 0.0092 0.0127
Brugia malayi ORL1-like opioid receptor 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0023
Echinococcus granulosus GPCR family 2 0.0049 0.0268 0.037
Echinococcus granulosus tachykinin peptides receptor 99D 0.0029 0.0122 0.0168
Onchocerca volvulus 0.0033 0.0148 0.0204
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0071 0.0049
Onchocerca volvulus 0.0029 0.0122 0.0168
Brugia malayi Trypsin family protein 0.0033 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0079 0.0489 0.0489
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0071 0.0049
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0186 0.0257
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0033 0.0148 0.0204
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0016 0.0028 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Schistosoma mansoni cercarial elastase (S01 family) 0.0033 0.0148 0.0203
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0122 0.0168
Schistosoma mansoni histamine h1 receptor 0.0029 0.0122 0.0167
Schistosoma mansoni topbp1 0.0016 0.0023 0.0031
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0122 0.0168
Echinococcus granulosus neuropeptide s receptor 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0148 0.0148
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.013 0.0108
Schistosoma mansoni hypothetical protein 0.0044 0.0231 0.0318
Brugia malayi Dopamine receptor protein 1 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0092
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0122 0.0122
Loa Loa (eye worm) Notch2 0.0014 0.0007 0.0007
Echinococcus multilocularis importin subunit beta 1 0.003 0.013 0.018
Brugia malayi hypothetical protein 0.0029 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.0122
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.1361 1 1
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0079 0.0489 0.0467
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0092 0.0092
Brugia malayi hypothetical protein 0.0016 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0122 0.0168
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0122 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0122 0.0167
Schistosoma mansoni sodium/chloride dependent transporter 0.0025 0.0092 0.0126
Echinococcus granulosus dro:myosuppressin receptor 0.0029 0.0122 0.0168

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

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