Detailed information for compound 1696996

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 384.426 | Formula: C21H24N2O5
  • H donors: 1 H acceptors: 2 LogP: 3.21 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)CCC1CNc2c1ccc(c2)OC(=O)N(c1ccc(cc1)OC)C
  • InChi: 1S/C21H24N2O5/c1-23(15-5-7-16(26-2)8-6-15)21(25)28-17-9-10-18-14(4-11-20(24)27-3)13-22-19(18)12-17/h5-10,12,14,22H,4,11,13H2,1-3H3
  • InChiKey: IWWFCVKNVCHFAV-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica P-glycoprotein 6, putative 0.0029 0.2983 0.3702
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0029 0.2983 0.279
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0714 0.0714
Schistosoma mansoni multidrug resistance protein 0.0067 0.8042 0.8042
Echinococcus multilocularis para nitrobenzyl esterase 0.0014 0.1025 0.1025
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0714 0.0714
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0029 0.2983 0.3794
Loa Loa (eye worm) hypothetical protein 0.0067 0.8042 0.8042
Entamoeba histolytica P-glycoprotein-2, putative 0.0028 0.2843 0.3529
Plasmodium vivax ABC transporter B family member 4, putative 0.0029 0.2983 0.3702
Trypanosoma brucei multidrug resistance protein E 0.0066 0.7847 1
Toxoplasma gondii ABC transporter, putative 0.0029 0.2983 0.3702
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0714 0.0714
Schistosoma mansoni BC026374 protein (S09 family) 0.0014 0.1025 0.1025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0714 0.0714
Brugia malayi hypothetical protein 0.0041 0.4587 0.4587
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0029 0.2983 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0714 0.0714
Brugia malayi ABC transporter family protein 0.0067 0.8042 0.8042
Echinococcus granulosus ATP binding cassette sub family B 0.0029 0.2983 0.2983
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.4587 0.4587
Echinococcus granulosus multidrug resistance protein 1 0.0067 0.8042 0.8042
Leishmania major pentamidine resistance protein 1 0.0066 0.7847 0.9757
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0067 0.8042 1
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0066 0.7847 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0067 0.8042 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0029 0.2983 0.2983
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0014 0.1025 0.1025
Schistosoma mansoni multidrug resistance protein 0.0067 0.8042 0.8042
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0028 0.2843 0.2843
Echinococcus granulosus ATP binding cassette sub family B 0.0029 0.2983 0.2983
Entamoeba histolytica hypothetical protein 0.0041 0.4587 0.5699
Loa Loa (eye worm) hypothetical protein 0.0011 0.0714 0.0714
Loa Loa (eye worm) hypothetical protein 0.0029 0.2983 0.2983
Echinococcus granulosus multidrug resistance protein 1 0.0067 0.8042 0.8042
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0029 0.2983 0.3702
Brugia malayi steroid hormone receptor 0.0011 0.0714 0.0714
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.4587 0.4587
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0028 0.2843 0.2591
Brugia malayi Carboxylesterase family protein 0.0014 0.1025 0.1025
Plasmodium falciparum multidrug resistance protein 1 0.0067 0.8042 1
Entamoeba histolytica P-glycoprotein-2 0.0067 0.8042 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0067 0.8042 1
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0714 0.0714
Loa Loa (eye worm) carboxylesterase 0.0014 0.1025 0.1025
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0067 0.8042 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0714 0.0714
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0714 0.0714
Entamoeba histolytica hypothetical protein 0.0041 0.4587 0.5699
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0714 0.0714
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0714 0.0714
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0714 0.0714
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0714 0.0714
Schistosoma mansoni smdr2 0.0067 0.8042 0.8042
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0067 0.8042 0.8042
Trypanosoma cruzi hypothetical protein 0.0037 0.4065 0.5175
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0066 0.7903 0.7903
Echinococcus granulosus multidrug resistance associated protein 7 0.0066 0.7847 0.7847
Giardia lamblia Multidrug resistance-associated protein 1 0.0064 0.7707 0.9721
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0714 0.0714
Echinococcus multilocularis ATP binding cassette sub family B 0.0066 0.7903 0.7903
Loa Loa (eye worm) hypothetical protein 0.0011 0.0714 0.0714
Leishmania major ABC-thiol transporter 0.0066 0.7847 0.9757
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0029 0.2983 0.3702
Plasmodium falciparum multidrug resistance-associated protein 1 0.0029 0.2983 0.3702
Schistosoma mansoni acetylcholinesterase 0.0014 0.1025 0.1025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0714 0.0714
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0714 0.0714
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0714 0.0714
Echinococcus granulosus BC026374 protein S09 family 0.0014 0.1025 0.1025
Loa Loa (eye worm) hypothetical protein 0.0014 0.1025 0.1025
Entamoeba histolytica ATP-binding cassette protein, putative 0.0066 0.7847 0.9757
Echinococcus granulosus multidrug resistance protein 1 0.0039 0.4399 0.4399
Loa Loa (eye worm) ABC transporter 0.0029 0.2983 0.2983
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0067 0.8042 1
Echinococcus granulosus ATP binding cassette sub family G 0.0006 0.0009 0.0009
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0029 0.2983 1
Schistosoma mansoni multidrug resistance protein 0.0066 0.7847 0.7847
Brugia malayi Carboxylesterase family protein 0.0014 0.1025 0.1025
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0067 0.8042 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0714 0.0714
Brugia malayi ABC transporter family protein 0.0029 0.2983 0.2983
Echinococcus granulosus multidrug resistance protein 1 0.0039 0.4399 0.4399
Entamoeba histolytica ATP-binding cassette protein, putative 0.0066 0.7847 0.9757
Schistosoma mansoni multidrug resistance protein 0.0029 0.2983 0.2983
Echinococcus granulosus multidrug resistance protein 1 0.0067 0.8042 0.8042
Brugia malayi multidrug resistance related protein 1 0.0066 0.7847 0.7847
Echinococcus granulosus para nitrobenzyl esterase 0.0014 0.1025 0.1025
Entamoeba histolytica P-glycoprotein 5, putative 0.0067 0.8042 1
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0066 0.7847 1
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0714 0.0714
Plasmodium vivax multidrug resistance protein 1, putative 0.0067 0.8042 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0714 0.0714
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0029 0.2983 0.5
Brugia malayi ABC transporter transmembrane region family protein 0.0028 0.2843 0.2843
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0029 0.2983 0.3702
Brugia malayi ABC transporter family protein 0.0029 0.2983 0.2983
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0714 0.0714
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0714 0.0714
Echinococcus multilocularis multidrug resistance associated protein 4 0.0037 0.4065 0.4065
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0029 0.2983 0.3794
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0029 0.2983 0.5
Echinococcus multilocularis ATP binding cassette sub family B 0.0029 0.2983 0.2983
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0714 0.0714
Plasmodium falciparum ABC transporter B family member 3, putative 0.0029 0.2983 0.3702
Plasmodium vivax ABC transporter B family member 3, putative 0.0029 0.2983 0.3702
Entamoeba histolytica multidrug resistance protein, putative 0.0066 0.7847 0.9757
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0067 0.8042 0.8042
Entamoeba histolytica P-glycoprotein 5, putative 0.0028 0.2843 0.3529
Plasmodium vivax ABC transporter B family member 5, putative 0.0029 0.2983 0.3702
Schistosoma mansoni hypothetical protein 0.0041 0.4587 0.4587
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0067 0.8042 1
Entamoeba histolytica P-glycoprotein-2 0.0067 0.8042 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0714 0.0714
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0082 1 1
Echinococcus multilocularis carboxylesterase 5A 0.0082 1 1
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0029 0.2983 0.3702
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0067 0.8042 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.1025 0.1025
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0066 0.7847 0.9757
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0029 0.2983 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0067 0.8042 0.8042
Onchocerca volvulus 0.0014 0.1025 0.0425
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0714 0.0714
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0067 0.8042 0.8042
Loa Loa (eye worm) hypothetical protein 0.0028 0.2843 0.2843
Loa Loa (eye worm) hypothetical protein 0.0014 0.1025 0.1025
Entamoeba histolytica ATP-binding cassette protein, putative 0.0066 0.7847 0.9757
Echinococcus multilocularis ATP binding cassette sub family B 0.0029 0.2983 0.2983
Echinococcus multilocularis ATP binding cassette sub family G 0.0006 0.0009 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0714 0.0714
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0067 0.8042 1
Echinococcus granulosus acetylcholinesterase 0.0082 1 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0714 0.0714
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0067 0.8042 0.8042
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0014 0.1025 0.1025
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0067 0.8042 1
Plasmodium vivax ABC transporter B family member 6, putative 0.0029 0.2983 0.3702
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0714 0.0714
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0714 0.0714
Loa Loa (eye worm) hypothetical protein 0.0011 0.0714 0.0714
Onchocerca volvulus 0.0067 0.8042 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0714 0.0714
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0029 0.2983 1
Schistosoma mansoni multidrug resistance protein 0.0066 0.7847 0.7847
Entamoeba histolytica hypothetical protein 0.0041 0.4587 0.5699
Loa Loa (eye worm) hypothetical protein 0.0066 0.7847 0.7847
Plasmodium vivax ABC transporter B family member 7, putative 0.0029 0.2983 0.3702
Toxoplasma gondii ABC transporter family protein 0.0029 0.2983 0.3702
Brugia malayi Carboxylesterase family protein 0.0082 1 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0714 0.0714
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0714 0.0714
Loa Loa (eye worm) hypothetical protein 0.0066 0.7847 0.7847
Loa Loa (eye worm) hypothetical protein 0.0011 0.0714 0.0714
Echinococcus multilocularis BC026374 protein (S09 family) 0.0014 0.1025 0.1025
Brugia malayi ABC transporter 0.0028 0.2843 0.2843
Loa Loa (eye worm) ABC transporter 0.0029 0.2983 0.2983
Loa Loa (eye worm) hypothetical protein 0.0011 0.0714 0.0714
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0014 0.1025 0.1025
Leishmania major p-glycoprotein e 0.0066 0.7847 0.9757
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0066 0.7847 0.7847
Loa Loa (eye worm) hypothetical protein 0.0064 0.7707 0.7707
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0029 0.2983 0.3702
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0714 0.0714
Trichomonas vaginalis abcb9, putative 0.0067 0.8042 1
Echinococcus multilocularis multidrug resistance protein 1 0.0067 0.8042 0.8042
Entamoeba histolytica P-glycoprotein-1 0.0067 0.8042 1
Echinococcus granulosus acetylcholinesterase 0.0082 1 1
Entamoeba histolytica P-glycoprotein-5 0.0067 0.8042 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0039 0.4399 0.4809
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0714 0.0714
Giardia lamblia MRP-like ABC transporter 0.0066 0.7847 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.1025 0.1025
Schistosoma mansoni multidrug resistance protein 0.0028 0.2843 0.2843
Echinococcus multilocularis acetylcholinesterase 0.0082 1 1
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0714 0.0714
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0067 0.8042 1
Trichomonas vaginalis ABC transporter, putative 0.0067 0.8042 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0029 0.2983 0.279
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0067 0.8042 1
Plasmodium falciparum ABC transporter B family member 5, putative 0.0029 0.2983 0.3702
Brugia malayi ABC transporter 0.0029 0.2983 0.2983
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0067 0.8042 1
Echinococcus granulosus ATP binding cassette sub family G 0.0006 0.0009 0.0009
Brugia malayi hypothetical protein 0.0014 0.1025 0.1025
Onchocerca volvulus 0.0014 0.1025 0.0425
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0067 0.8042 0.8042
Loa Loa (eye worm) hypothetical protein 0.0011 0.0714 0.0714
Onchocerca volvulus 0.0014 0.1025 0.0425
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0029 0.2983 0.3702
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0029 0.2983 0.3702
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0029 0.2983 0.3794
Loa Loa (eye worm) multidrug resistance protein 3 0.0067 0.8042 0.8042
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0067 0.8042 0.8042
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0714 0.0714
Onchocerca volvulus 0.0014 0.1025 0.0425
Loa Loa (eye worm) carboxylesterase 0.0014 0.1025 0.1025
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0714 0.0714
Mycobacterium ulcerans carboxylesterase, LipT 0.0014 0.1025 0.3418
Plasmodium falciparum multidrug resistance-associated protein 2 0.0029 0.2983 0.3702
Trichomonas vaginalis taga, putative 0.0067 0.8042 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.1025 0.1025
Loa Loa (eye worm) multidrug resistance-associated protein 0.0038 0.4204 0.4204
Echinococcus multilocularis ATP binding cassette sub family G 0.0006 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.2843 0.2591
Trichomonas vaginalis ABC transporter, putative 0.0067 0.8042 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0714 0.0714
Echinococcus granulosus neuroligin 0.0014 0.1025 0.1025
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.4587 0.4587
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0006 0.0009 0.0009
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0067 0.8042 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0714 0.0714
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0714 0.0714
Trichomonas vaginalis ABC transporter, putative 0.0067 0.8042 1
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0066 0.7847 0.9757
Leishmania major p-glycoprotein 0.0067 0.8042 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0066 0.7847 1
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0029 0.2983 0.5
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0714 0.0714
Plasmodium falciparum multidrug resistance protein 2 0.0029 0.2983 0.3702
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0067 0.8042 1
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0066 0.7847 0.9757
Echinococcus multilocularis 0.0029 0.2983 0.2983
Entamoeba histolytica hypothetical protein 0.0066 0.7847 0.9757
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0714 0.0714
Entamoeba histolytica ABC transporter, putative 0.0066 0.7847 0.9757
Loa Loa (eye worm) hypothetical protein 0.0066 0.7903 0.7903
Plasmodium falciparum ABC transporter B family member 7, putative 0.0029 0.2983 0.3702
Trypanosoma cruzi multidrug resistance protein E, putative 0.0066 0.7847 1
Echinococcus granulosus carboxylesterase 5A 0.0082 1 1
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0029 0.2983 0.3702
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0029 0.2983 0.3702
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0028 0.2843 0.2591
Loa Loa (eye worm) hypothetical protein 0.0011 0.0714 0.0714
Brugia malayi P-glycoprotein-like protein 0.0029 0.2983 0.2983
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0714 0.0714
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0029 0.2983 0.2983
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0714 0.0714
Entamoeba histolytica ATP-binding cassette protein, putative 0.0066 0.7847 0.9757
Echinococcus granulosus ATP binding cassette sub family B 0.0028 0.2843 0.2843
Brugia malayi ABC transporter transmembrane region family protein 0.0066 0.7847 0.7847
Echinococcus multilocularis ATP binding cassette sub family G 0.0006 0.0009 0.0009
Schistosoma mansoni multidrug resistance protein 0.0067 0.8042 0.8042
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0714 0.0714
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0714 0.0714
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0014 0.1025 0.1025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0714 0.0714
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0029 0.2983 0.3702
Echinococcus granulosus multidrug resistance associated protein 1 0.0066 0.7847 0.7847
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0067 0.8042 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0067 0.8042 1
Echinococcus multilocularis multidrug resistance protein 1 0.0067 0.8042 0.8042
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0067 0.8042 1
Brugia malayi nuclear receptor NHR-88 0.0011 0.0714 0.0714
Loa Loa (eye worm) hypothetical protein 0.0014 0.1025 0.1025
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0067 0.8042 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0714 0.0714
Brugia malayi Carboxylesterase family protein 0.0014 0.1025 0.1025
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0028 0.2843 0.2591
Echinococcus multilocularis acetylcholinesterase 0.0082 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0067 0.8042 1
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0029 0.2983 0.5
Echinococcus multilocularis ATP binding cassette sub family B 0.0029 0.2983 0.2983
Brugia malayi nuclear hormone receptor 0.0011 0.0714 0.0714
Brugia malayi ecdysteroid receptor 0.0011 0.0714 0.0714
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0066 0.7847 0.9757
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0714 0.0714
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0029 0.2983 0.3794
Loa Loa (eye worm) ABC transporter 0.0029 0.2983 0.2983
Loa Loa (eye worm) hypothetical protein 0.0082 1 1
Giardia lamblia ABC transporter, putative 0.0066 0.7847 1
Schistosoma mansoni multidrug resistance protein 0.0066 0.7847 0.7847
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0067 0.8042 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.8042 0.8042
Loa Loa (eye worm) carboxylesterase 0.0082 1 1
Schistosoma mansoni gliotactin 0.0014 0.1025 0.1025
Brugia malayi multidrug resistance protein 3 0.0067 0.8042 0.8042
Echinococcus granulosus multidrug resistance associated protein 4 0.0037 0.4065 0.4065
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0714 0.0714
Giardia lamblia Multidrug resistance-associated protein 1 0.0066 0.7847 1
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0066 0.7847 1
Entamoeba histolytica hypothetical protein 0.0041 0.4587 0.5699
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0714 0.0714
Trichomonas vaginalis ABC transporter, putative 0.0067 0.8042 1
Plasmodium falciparum ABC transporter B family member 6, putative 0.0029 0.2983 0.3702
Trypanosoma brucei p-glycoprotein 0.0066 0.7847 1
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0029 0.2983 0.2983
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0014 0.1025 0.1025
Loa Loa (eye worm) acetylcholinesterase 1 0.0082 1 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0714 0.0714
Echinococcus multilocularis neuroligin 0.0014 0.1025 0.1025
Plasmodium falciparum ABC transporter B family member 4, putative 0.0029 0.2983 0.3702
Echinococcus multilocularis multidrug resistance protein 1 0.0039 0.4399 0.4399
Brugia malayi hypothetical protein 0.0029 0.2983 0.2983
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0066 0.7847 1
Entamoeba histolytica P-glyco protein 6, putative 0.0067 0.8042 1
Brugia malayi ABC transporter transmembrane region family protein 0.0029 0.2983 0.2983
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0067 0.8042 0.8042
Trichomonas vaginalis abcb9, putative 0.0067 0.8042 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0029 0.2983 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0067 0.8042 0.8042
Echinococcus granulosus ATP binding cassette sub family G 0.0006 0.0009 0.0009
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0029 0.2983 0.279
Loa Loa (eye worm) hypothetical protein 0.0014 0.1025 0.1025
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0714 0.0714
Trichomonas vaginalis abcb9, putative 0.0067 0.8042 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0066 0.7847 0.9757
Entamoeba histolytica P-glycoprotein-2, putative 0.0067 0.8042 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0067 0.8042 1
Brugia malayi ABC transporter family protein 0.0029 0.2983 0.2983
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0714 0.0714
Echinococcus multilocularis multidrug resistance associated protein 1 0.0066 0.7847 0.7847
Schistosoma mansoni neuroligin 3 (S09 family) 0.0014 0.1025 0.1025
Entamoeba histolytica P-glycoprotein 6, putative 0.0029 0.2983 0.3702
Plasmodium vivax multidrug resistance protein 2, putative 0.0029 0.2983 0.3702
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0067 0.8042 0.8042
Onchocerca volvulus 0.0014 0.1025 0.0425
Schistosoma mansoni coup transcription factor 0.0011 0.0714 0.0714
Echinococcus multilocularis multidrug resistance associated protein 7 0.0066 0.7847 0.7847
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0067 0.8042 0.5
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0714 0.0714
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0067 0.8042 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0067 0.8042 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0067 0.8042 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0029 0.2983 0.3702
Schistosoma mansoni multidrug resistance protein 0.0066 0.7847 0.7847
Schistosoma mansoni smdr1 0.0029 0.2983 0.2983
Loa Loa (eye worm) hypothetical protein 0.0011 0.0714 0.0714
Brugia malayi Carboxylesterase family protein 0.0014 0.1025 0.1025
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0067 0.8042 1
Loa Loa (eye worm) hypothetical protein 0.0082 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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